CN110151982A - A kind of Chinese medicine composition for treating gout - Google Patents
A kind of Chinese medicine composition for treating gout Download PDFInfo
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- CN110151982A CN110151982A CN201910426936.3A CN201910426936A CN110151982A CN 110151982 A CN110151982 A CN 110151982A CN 201910426936 A CN201910426936 A CN 201910426936A CN 110151982 A CN110151982 A CN 110151982A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/02—Algae
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/346—Platycodon
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
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Abstract
The present invention relates to field of traditional Chinese medicine formula, disclose a kind of Chinese medicine composition for treating gout, it include Chinese medicine material and collagen, the Chinese medicine material includes pueraria lobata, the root of Dahurain angelica, the sophora bud, campanulaceae and seaweed, the mass parts ratio of the Chinese medicine material are as follows: 0.5~2 part of pueraria lobata, 1~2 part of the root of Dahurain angelica, 0.5~3 part of the sophora bud, 0.3~1 part and 1~3 part of seaweed of campanulaceae, it is 0.5~2 part that described collagen quality part, which is compared, the raw material of Chinese medicine preparation of the invention is mostly Chinese medicine, Chinese medicine used is to human body almost without toxicity, more damage will not be caused to human body, the active drug ingredient in human drug absorption's composition can be effectively helped using collagen, preferably play the pharmacological property of Chinese medicine material, Chinese medicine composition of the invention can effectively treat due to uric acid it is excessively high caused by gout Disease.
Description
Technical field
The present invention relates to field of traditional Chinese medicine formula, especially a kind of Chinese medicine composition for treating gout.
Background technique
Gout is a kind of disease caused by purine metabolic disturbance.Clinical manifestation is hyperuricemia and lithate knot
Characteristic acute arthritis caused by crystalline substance deposition, tophus formation, tophaceous chornic arthritis, and lithate kidney can occur
Sick, uric acid lithangiuria etc., serious person may occur in which joint disable, renal insufficiency.The prerequisite of gout morbidity is high urine
Acidaemia, therefore, hyperuricemia are the most important biochemical basis of gout, and followed by uric acid mineralization causes inflammatory reaction.With
The improvement of people's living standards, in recent years due to the change of dietary structure, the intake of alcohol especially beer class drink increases
And the reduction of muscular labor momentum, cause the disease incidence of hyperuricemia and primary gout in the trend that rises year by year, and fall ill
Age presentation becomes younger.The disease is since hypersaturated state is presented in uric acid in blood, other than causing directly to damage to bone, joint,
Kidney can be also deposited on and cause nephropathy, there are biggish danger to the harm of human health, receive the extensive pass of medical field
Note.
The product that modern medicine now treats gout can only solve anti-trioxypurine, cannot be dissolving crystallized, lead to gout recurrent exerbation,
And to kidney there is a great harm for.Anti-trioxypurine product currently on the market is all that Western medicine includes Allopurinol, Febustat, Benzbromarone
Deng, therefore, doctor trained in Western medicine means clinical treatment ventilation receive certain restrictions.
Summary of the invention
The purpose of the present invention is to provide a kind of Chinese medicine compositions for treating gout, to solve problem of the prior art.
To realize above-mentioned technical purpose and the technique effect, the invention discloses a kind of Chinese medicine groups for treating gout
Close object, which is characterized in that include Chinese medicine material and collagen, the Chinese medicine material includes pueraria lobata, the root of Dahurain angelica, the sophora bud, tangerine
Stalk and seaweed, the mass parts ratio of the Chinese medicine material are as follows: 0.5~2 part of pueraria lobata, 1~2 part of the root of Dahurain angelica, 0.5~3 part of the sophora bud, campanulaceae
0.3~1 part and 1~3 part of seaweed, it is 0.5~2 part that described collagen quality part, which is compared,.
The medicinal material function parsing of Chinese medicine composition is as follows:
Pueraria lobata is sweet, pungent, cool；Major function: expelling pathogenic factors from muscles and skin is brought down a fever, promoting eruption promotes the production of body fluid to quench thirst, the function of Shengyang Zhixie, is usually used in exterior syndrome hair
Heat, stiff nape and back, measles without adequate eruption, pyreticosis is thirsty, and the deficiency of Yin is quenched one's thirst, and heat is purged heat dysentery, splenasthenic diarrhea, and Ge Gegen can make the generation of uric acid
It reduces.
The root of Dahurain angelica, it is acrid in flavour and warm in nature；Major function: expelling wind and clearing away cold, sensible analgesic, detumescence and apocenosis, eliminating dampness stops band, for having a headache, tooth
Bitterly, nasosinusitis, intestines wind anal fistula, leukorrhea with reddish discharge, ulcer sores, pruitus.
The sophora bud, cold nature, bitter；Major function: cooling blood and hemostasis, clearing liver-fire.For hematochezia, hemorrhoid blood, bloody flux, metrorrhagia and metrostaxis,
Haematemesis, bleeding from five sense organs or subcutaneous tissue, liver heat, red eyes, headache, dizziness.
Campanulaceae, it is pungent, it is bitter；Major function: exogenous cough, abscess of throat, lung carbuncle pyemesis, chest are controlled in open the inhibited lung-energy, eliminating the phlegm apocenosis
Full hypochondriac pain, dysentery abdominal pain.
Collagen has good biocompatibility, biodegradable and bioactivity, in vivo easily by human body
It absorbs, cellular activities and growth can be promoted, promote coagulating platelets；It is obtained in fields such as food, medicine, organizational project, cosmetics
It must be widely applied.
Seaweed, it is bitter, salty, it trembles with fear；Major function: softening hard masses, dissolving phlegm, Li Shui expel the heat-evil.Control scrofula, goiter, accumulation, oedema, foot
Gas, testiclar gall, the main ingredient of seaweed is containing alkaloids and flavones can play reduces uric acid concentration and dissolution joint urine
Acid crystal effect.
It is evidenced from the above discussion that the raw material of pharmaceutical composition of the invention is mostly Chinese medicine, above-mentioned Chinese medicine is to people
Body will not cause more damage to bear to human body, use collagen can be effective as raw material simply almost without toxicity
Help human drug absorption's composition drug molecule, the effective pharmacological property for playing Chinese medicine material reaches the effect for the treatment of gout
Fruit.
Further, the mass parts ratio of preferred Chinese medicine material are as follows: 1 part of pueraria lobata, 1 part of the root of Dahurain angelica, 1 part of the sophora bud, 1 part of campanulaceae and sea
1 part of algae, the mass parts ratio of preferred collagen is 1 part.
It is evidenced from the above discussion that preferred material quality part than can the sufficiently effective pharmacological property for playing each medicinal material, together
When enable to the pharmacological property between medicinal material not conflict with each other again, excessive side effect will not be caused to human body.
Further, the pharmaceutical composition further comprises pharmaceutically common auxiliary material, and the auxiliary material includes filler
And wetting agent, the filler be starch, dextrin, lactose, sucrose, microcrystalline cellulose, glucose, Glucosamine, mannitol,
One of calcium sulfate or calcium bisulfate are a variety of；The wetting agent is water or ethyl alcohol.
It is evidenced from the above discussion that the auxiliary material does not have physiological activity, main effect contributes to the steady of pharmaceutical composition
It is fixed, as long as the effect of filler is for packing volume to which dilution is main, convenient for the preparations shaping of pharmaceutical composition, wetting agent
Main function be the viscosity with Chinese medicine itself induce come, facilitate the bonding of drug.
Further, the mass ratio of the auxiliary material and Chinese medicine material is 10~20:1.
It is evidenced from the above discussion that the proportion of auxiliary material appropriate and main ingredient can preferably realize the carrying and medicine group of drug
Close the control of object clinically dosage.
A kind of preparation method of Chinese medicine composition that treating gout, by Chinese medicine material pueraria lobata, the root of Dahurain angelica, the sophora bud, campanulaceae and sea
Algae breaks into powdery respectively；Choose the powderous preparations collagen protein powder of collagen；By collagen protein powder and kudzu-vine root powder, angelica dahurica powder,
Sophora bud powder, balloonflower powder, seawood meal are mixed and made into powder；Powder and auxiliary material are mixed to prepare Chinese medicine composition.
It, can be with by being mixed to prepare with the powder of raw material it is evidenced from the above discussion that by crushing medicine material
So that the mixing between raw material is more uniform, it is more advantageous to various Chinese medicines and plays and respective cure mainly function.
Further, the mesh number of powdery Chinese medicine material is 150~300 mesh.
It is evidenced from the above discussion that the powdery Chinese medicine material of 150~300 mesh can be convenient the mixed process of Chinese medicine composition,
It is also beneficial to absorption of the patient to bioactive molecule in Chinese traditional medicine composition simultaneously.
A kind of application of Chinese medicine composition that treating gout in preparation treatment gout drug, the Chinese medicine composition choosing
Customary adjuvant is added in selecting property, and routinely clinically acceptable preparation is made in technique, and the preparation includes powder, pill, piece
Agent, electuary and granule.
It is evidenced from the above discussion that facilitating taking for patient by the way that Chinese medicine composition is prepared into various preparations.
The invention has the following advantages: the raw material of Chinese medicine preparation of the invention is mostly Chinese medicine, Chinese medicine used
To human body almost without toxicity, more damage will not be caused to human body, effectively human body can be helped to inhale using collagen
The active drug ingredient in pharmaceutical composition is received, preferably plays the pharmacological property of Chinese medicine material, Chinese medicine composition of the invention can
Effective treatment due to uric acid it is excessively high caused by gout.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, with reference to embodiments, to the present invention
It is further elaborated.
Embodiment 1
Chinese medicine composition is by 1 part of kudzu-vine root powder, 1 part of angelica dahurica powder, 1 part of sophora bud powder, 1 part of balloonflower powder, 1 part of collagen protein powder and seawood meal
1 part is mixed to prepare for raw material, and powder preparation formulation is made in Chinese medicine composition.
Embodiment 2
Chinese medicine composition is by 2 parts of kudzu-vine root powder, 1 part of angelica dahurica powder, 0.5 part of sophora bud powder, 0.3 part of balloonflower powder, 1 part of collagen protein powder, sea
3 parts of algae powder and auxiliary material are mixed to prepare for raw material, and filler is starch and dextrin in auxiliary material, and wetting agent is water, and auxiliary material and Chinese medicine are former
The mass ratio of material is 10:1, and electuary dosage form is made in Chinese medicine composition.
Embodiment 3
Chinese medicine composition is by 1 part of kudzu-vine root powder, 1 part of angelica dahurica powder, 2 parts of sophora bud powder, 0.5 part of balloonflower powder, 1 part of collagen protein powder, seaweed
2 parts of powder and auxiliary material are mixed to prepare for raw material, and filler is starch and microcrystalline cellulose in auxiliary material, and wetting agent is water, and auxiliary material is in
The mass ratio of medicine raw material is 15:1, and powder preparation formulation is made in Chinese medicine composition.
Application method of the invention are as follows: warm water takes or boiled water is taken after being infused in hot water or decoction, and daily 1 dose, 7 doses as a treatment course, needs medication 1-6
The course for the treatment of.
The following are case introductions:
1, Mr. Lin, male 66 years old, suffer from serious arthritis and arthralgia due to caused by uric acid, check display joint accumulation
There is more uric acid crystal, after taking 4 courses for the treatment of of medicinal composition powders of the invention, patient articular's pain symptom is completely slow
Solution.
2, Mr. Wang, female 43 years old, suffer from gout, and each arthroncus of foot is serious, when morbidity each joint severe pain,
After taking 6 courses for the treatment of of medicinal composition powders of the invention, patient articular's pain symptom complete incidence graph, internal uric acid are returned back to just
Ordinary water is flat.
3, Liang, male, 54 years old, asymptomatic hyperuricemia, 634 μm of ol/L of physical examination uric acid took medicine group of the invention
After closing 1 course for the treatment of of object pill, 403 μm of ol/L of physical examination uric acid.
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto,
In the technical scope disclosed by the present invention, any changes or substitutions that can be easily thought of by anyone skilled in the art,
It should be covered by the protection scope of the present invention.
Claims (7)
1. a kind of Chinese medicine composition for treating gout, which is characterized in that include Chinese medicine material and collagen, the Chinese medicine
Raw material includes pueraria lobata, the root of Dahurain angelica, the sophora bud, campanulaceae and seaweed, the mass parts ratio of the Chinese medicine material are as follows: 0.5~2 part of pueraria lobata, white
1~2 part of the root of Dahurian angelica, 0.5~3 part of the sophora bud, 0.3~1 part of campanulaceae and 1~3 part of seaweed, it is 0.5~2 that described collagen quality part, which is compared,
Part.
2. a kind of Chinese medicine composition for treating gout as described in claim 1, it is characterised in that: the matter of preferred Chinese medicine material
Measure part ratio are as follows: 1 part of pueraria lobata, 1 part of the root of Dahurain angelica, 1 part of the sophora bud, 1 part of campanulaceae and 1 part of seaweed, the mass parts ratio of preferred collagen are 1
Part.
3. a kind of Chinese medicine composition for treating gout as claimed in claim 1 or 2, it is characterised in that: further comprise pharmaceutically
Common auxiliary material, the auxiliary material include filler and wetting agent, and the filler is starch, dextrin, lactose, sucrose, crystallite
One of cellulose, glucose, Glucosamine, mannitol, calcium sulfate or calcium bisulfate are a variety of；The wetting agent is
Water or ethyl alcohol.
4. a kind of Chinese medicine composition for treating gout as claimed in claim 3, it is characterised in that: the auxiliary material and Chinese medicine is former
The mass ratio of material is 10~20:1.
5. the preparation method of the Chinese medicine composition of any one as claimed in claim 4 treatment gout, it is characterised in that: will in
Medicine raw material pueraria lobata, the root of Dahurain angelica, the sophora bud, campanulaceae and seaweed break into powdery respectively；Choose the powderous preparations collagen protein powder of collagen；
Collagen protein powder and kudzu-vine root powder, angelica dahurica powder, sophora bud powder, balloonflower powder, seawood meal are mixed and made into powder；Powder is mixed with auxiliary material
Chinese medicine composition is made.
6. a kind of preparation method for the Chinese medicine composition for treating gout as claimed in claim 5, it is characterised in that: the powder
The mesh number of shape Chinese medicine material is 150~300 mesh.
7. the Chinese medicine composition of any one treatment gout as described in Claims 1 to 4 is in preparation treatment gout drug
Using, it is characterised in that: the Chinese medicine composition selectively adds customary adjuvant, and routinely technique, which is made, is clinically subjected to
Preparation, the preparation includes powder, pill, tablet, electuary and granule.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201910426936.3A CN110151982A (en) | 2019-05-22 | 2019-05-22 | A kind of Chinese medicine composition for treating gout |
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| CN201910426936.3A CN110151982A (en) | 2019-05-22 | 2019-05-22 | A kind of Chinese medicine composition for treating gout |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110623182A (en) * | 2019-10-10 | 2019-12-31 | 胡洁 | Probiotic plant solid beverage for treating hyperuricemia and gout |
| CN111529575A (en) * | 2020-05-29 | 2020-08-14 | 鲁雪梅 | A pharmaceutical composition for treating gout and/or hyperuricemia, and its preparation method |
| CN111760014A (en) * | 2020-07-20 | 2020-10-13 | 厦门植喜生物科技有限公司 | A composition for reducing acid and invigorating kidney, and its preparation method |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110623182A (en) * | 2019-10-10 | 2019-12-31 | 胡洁 | Probiotic plant solid beverage for treating hyperuricemia and gout |
| CN111529575A (en) * | 2020-05-29 | 2020-08-14 | 鲁雪梅 | A pharmaceutical composition for treating gout and/or hyperuricemia, and its preparation method |
| CN111760014A (en) * | 2020-07-20 | 2020-10-13 | 厦门植喜生物科技有限公司 | A composition for reducing acid and invigorating kidney, and its preparation method |
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Application publication date: 20190823 |