CN1100944A

CN1100944A - Prepared Chinese medicine for curing tumor of digestive canal system

Info

Publication number: CN1100944A
Application number: CN 93121390
Authority: CN
Inventors: 张校苏
Original assignee: Individual
Current assignee: Individual
Priority date: 1993-12-31
Filing date: 1993-12-31
Publication date: 1995-04-05

Abstract

The present invention relates to a Chinese patent drug for curing tumor of digestive tract system. Said invention uses the Chinese medicines of leech, red sage root and sal ammoniac, etc. as main materials to act for promoting blood circulation by removing blood stasis, resolving the hard lumps and removing the focus of carcinomatosis, uses cow-bezoare and musk to act for clearing away heat and detoxicating, and uses astragalus root and ginseng to act for enriching the blood, invigorating qi and strengthening the body resistance, and at the same time adds the trace elements of germanium and selenium, etc. to act for raising antioxidation and promoting cellular metabolism. Its curative effect is good, toxicity is low and cost is cheap.

Description

Prepared Chinese medicine for curing tumor of digestive canal system

The invention belongs to a kind of Chinese patent medicine based on treatment gi system tumor.

Digestive tract cancer accounts for 60% of malignant tumor, the serious harm human health, traditional Therapeutic Method is operation, radiotherapy, chemotherapy, or several method is comprehensive, but majority had been middle and advanced stage when this class cancer was made a definite diagnosis, thus lost operative treatment opportunity, thereby many people are in the method for research Drug therapy.

It is better that the present invention aims to provide a kind of curative effect, low price, the Chinese patent medicine based on treatment gi system tumor that toxic and side effects is little.

For reaching above-mentioned purpose, the present invention adopts following prescription, and every dose of patent medicine composition of raw materials is:

Radix Ginseng 5-9g Radix Angelicae Sinensis 15-25g Radix Astragali 15-30g

Radix Rehmanniae Preparata 15-30g Fructus Aurantii Immaturus 10-20g Borneolum Syntheticum is an amount of

Exocarpium Juglandis Immaturus 10-20g Placenta Hominis 3-10g Hirudo 0.2-0.5g

Radix Salviae Miltiorrhizae 5-15g Sal Ammoniacus 0.05-0.1g Venenum Bufonis 0.1-0.2g

Scolopendra 1-3 bar Scorpio 0.3-0.5g Calculus Bovis 0.1-0.8g

Moschus 0.3-0.5g Herba Scutellariae Barbatae 15-20g Mylabris 0.1-0.2g

Rhizoma Curcumae 0.2-0.3g Radix Notoginseng 15-30g Radix Panacis Quinquefolii 0.6-0.8g

Agkistrodon 15-30g germanium 0.2-0.3g selenium 0.05-0.2g

Zinc 0.03-0.06g

Hirudo in the above-mentioned prescription, Sal Ammoniacus, Scolopendra, Scorpio, Mylabris, Agkistrodon detoxification are handled, be crushed into powder, Radix Ginseng, Radix Angelicae Sinensis, the Radix Astragali, Radix Rehmanniae Preparata, Fructus Aurantii Immaturus, Exocarpium Juglandis Immaturus, Radix Salviae Miltiorrhizae, Herba Scutellariae Barbatae, Radix Notoginseng soaked respectively to concentrate after the heating extraction be dried into powder, Placenta Hominis is soaked the concentration extraction oven dry be crushed to powder, other one-tenth is divided into powder, fully mix again, make the patent medicine of various dosage forms with conventional Chinese medicine manufacture method.

Cancer mainly is by stagnation of QI due to depression of the liver, blood stasis, the spleen-cold syndrome deficiency of vital energy, form that diaphragm is choked, regurgitation, the abdominal mass stasis of blood are gathered.The present invention adopts blood circulation promoting and blood stasis dispelling, hardness softening and stasis-eliminating, and prescription non-return, benefiting QI and nourishing blood reduces phlegm.This prescription serves as main row blood circulation promoting and blood stasis dispelling with Hirudo, Radix Salviae Miltiorrhizae, Sal Ammoniacus, Venenum Bufonis, Scolopendra, Scorpio, Mylabris etc.; knot softening the hard mass, putrefaction removing and tissue regeneration promoting disappear; play and remove cancer originally; the effect of cancer disappears; effect with row heat-clearing and toxic substances removing such as Calculus Bovis, Moschus, Herba Scutellariae Barbatae, Exocarpium Juglandis Immaturus; with row invigorating QI and bloods such as the Radix Astragali, Radix Ginseng, Placenta Hominiss; the effect of the body resistance strengthening and constitution consolidating; be equipped with germanium, selenium and other trace elements simultaneously; play the increase antioxidation, participate in cellular metabolism, the supply of blocking-up cancerous cell energy; thereby anticancer division and propagation promote the effect of body's immunity.

Above-mentioned Chinese patent medicine is used for 60 routine clinical observations, except that seriously ill weakling gives anti symptom treatment and fluid infusion nutritional support, stops other anticancer therapy, single this Chinese patent medicine of clothes, average medication 48.8 days, average dosage 0.5g * 429.5 (capsule formulation), observe as follows:

1, subjective symptom is improved: 14 example feed difficulties have alleviation in various degree in the 18 routine esophageal carcinoma, obstruct the minimizing of choking, and 19 routine abdominal distention are painful in 26 routine cardia-gastric cancer alleviates, and feed increases, and 4 routine pain disappear substantially in the 7 routine hepatocarcinoma, and the symptom improvement rate reaches 72.5%.

2, recent objective curative effect: treatment anteroposterior diameter X line is taken the photograph sheet, B ultrasonic, the measurement contrast of endoscope and visible tumor, alleviate (CR) 1 example fully, part is alleviated (PR) 2 examples, (MR) 3 examples take a turn for the better, stable (SD) 29 examples; pathological development (PD) 25 examples are alleviated improvement rate 10%, coefficient of stabilization 48.3%; total effective rate (CR+PR+MP+SD) 58.3%; esophageal carcinoma wherein; cardia-gastric cancer effective percentage reaches 65%, intestinal cancer 50%, hepatocarcinoma; the pulmonary carcinoma effective percentage is lower; (seeing Table 1); with present curative effect preferably FUFANG TIANXIAN WAN (Changbai mountain, Jilin pharmaceutical factory) compare remission rate; improvement rate is higher than TIANXIAN WAN, but coefficient of stabilization is lower than TIANXIAN WAN (seeing Table 2).

Table 1: this Chinese patent medicine centering stage tract cancer curative effect

Table 2: this Chinese patent medicine compares with the TIANXIAN WAN curative effect

Observation to clinical toxic and side effects, after a few patients is taken, have the of short duration slight stomach discomfort, do not see the reflection of the above toxicity of II degree, the contrast peripheral blood phase change prompting hemopoietic function improvement that generally increases after the 47 routine medications, conscience function no abnormality seen meets clinical low toxicity requirement (seeing Table 3).

Table 3: this Chinese patent medicine disappears the cancer spirit to 47 routine patient's hemopoietic and the heart, liver function influence

With this Chinese patent drugs for treatment digestive tract tumor, can obtain curative effect preferably, and toxic and side effects is little, low price.

Embodiment 1: every dose of patent medicine composition of raw materials of present embodiment is:

Radix Ginseng 7g Radix Angelicae Sinensis 18g Radix Astragali 20g Radix Rehmanniae Preparata 20g

An amount of Exocarpium Juglandis Immaturus 18g of Fructus Aurantii Immaturus 13g Borneolum Syntheticum Placenta Hominis 5g

Hirudo 0.3g Radix Salviae Miltiorrhizae 8g Sal Ammoniacus 0.05g Venenum Bufonis 0.15g

2 Scorpio 0.4g of Scolopendra Calculus Bovis 0.3g Moschus 0.4g

Herba Scutellariae Barbatae 13g Mylabris 0.1g Rhizoma Curcumae 0.2g Radix Notoginseng 20g

Radix Panacis Quinquefolii 0.6g Agkistrodon 20g germanium 0.2g selenium 0.1g

Zinc 0.05g

Get material by above-mentioned every dose of patent medicine proportioning raw materials, with the Hirudo in the prescription, Scolopendra, Scorpio, Agkistrodon, Mylabris carries out detoxification with the animal method and handles, the method of promptly using feeding is with the digestive tract of these a few flavor medicines by chicken, get its Excreta, and then the digestive viscera of taking out chicken makes five poisonous creatures: scorpion, viper, centipede, house lizard, toad essence through concocting to extract with Excreta, be crushed into powder, again with Radix Ginseng, Radix Angelicae Sinensis, the Radix Astragali, Radix Rehmanniae Preparata, Fructus Aurantii Immaturus, Exocarpium Juglandis Immaturus, Radix Salviae Miltiorrhizae, Herba Scutellariae Barbatae, Radix Notoginseng is soaked respectively to concentrate after the heating extraction and is dried into powder, the Placenta Hominis oven dry is crushed to powder, all the other material compositions are pressed into powder, fully mix again, make capsule formulation.

Embodiment 2: every dose of patent medicine composition of raw materials of present embodiment is:

Radix Ginseng 9g Radix Angelicae Sinensis 23g Radix Astragali 25g Radix Rehmanniae Preparata 25g

An amount of Exocarpium Juglandis Immaturus 13g of Fructus Aurantii Immaturus 18g Borneolum Syntheticum Placenta Hominis 8g

Hirudo 0.4g Radix Salviae Miltiorrhizae 13g Sal Ammoniacus 0.1g Venenum Bufonis 0.1g

3 Scorpio 0.5g of Scolopendra Calculus Bovis 0.6g Moschus 0.5g

Herba Scutellariae Barbatae 18g Mylabris 0.2g Rhizoma Curcumae 0.3g Radix Notoginseng 25g

Radix Panacis Quinquefolii 0.8g Agkistrodon 25g germanium 0.3g selenium 0.15g

Zinc 0.04g

Concocting method is with embodiment 1.

Claims

1, the Chinese patent medicine of treatment digestive system tumor, it is characterized in that: every dose of patent medicine composition of raw materials is:

Radix Ginseng 5-9g Radix Angelicae Sinensis 15-25g Radix Astragali 15-30g

Exocarpium Juglandis Immaturus 10-20g Placenta Hominis 3-10g Hirudo 0.2-0.5g

Scolopendra 1-3 bar Scorpio 0.3-0.5g Calculus Bovis 0.1-0.8g

Moschus 0.3-0.5g Herba Scutellariae Barbatae 15-20g Mylabris 0.1-0.2g

Agkistrodon 15-30g germanium 0.2-0.3g selenium 0.05-0.2g

Zinc 0.03-0.06g

Poisonous raw material in the mentioned component after detoxification is handled, is made the Chinese patent medicine of capsule or other dosage form again with other raw material.

2, Chinese patent medicine as claimed in claim 1, it is characterized in that: it is to adopt the animal facture that the detoxification of the Hirudo in the described raw material, Scolopendra, Scorpio, Mylabris, Agkistrodon is handled, the method of promptly using feeding is with the digestive tract of these a few flavor medicines by chicken, get its Excreta, and then the digestive viscera of taking-up chicken makes five poisonous creatures: scorpion, viper, centipede, house lizard, toad essence through concocting to extract with Excreta.