CN110013508A - A kind of Traditional Chinese medicinal liquor improving antitumor immunity - Google Patents
A kind of Traditional Chinese medicinal liquor improving antitumor immunity Download PDFInfo
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- CN110013508A CN110013508A CN201810012891.0A CN201810012891A CN110013508A CN 110013508 A CN110013508 A CN 110013508A CN 201810012891 A CN201810012891 A CN 201810012891A CN 110013508 A CN110013508 A CN 110013508A
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/344—Codonopsis
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
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Abstract
The invention discloses a kind of Traditional Chinese medicinal liquors for improving antitumor immunity; including following raw medicinal material: matsutake, medical stone, yellow wood, radix tetrastigme micro powder, mushroom, Radix Astragali, Radix Codonopsis and fructus lycii; it is preferable to use the mushrooms of Wutai, Shanxi Province for mushroom; lentinan powder is made by processing in mushroom; the matsutake with radix tetrastigme micro powder, after milled processed, the medical stone after milled processed, the yellow wood after milled processed are mixed and are dissolved in 450-550ml yellow rice wine lentinan powder respectively, and last Radix Astragali, Radix Codonopsis and fructus lycii are immersed in 450-550ml yellow rice wine.The present invention in yellow rice wine by having incorporated lentinan powder, so that Traditional Chinese medicinal liquor has effects that improve antitumor immunity, additionally by yellow wood, radix tetrastigme micro powder and medical stone has also been incorporated in yellow rice wine, so that Traditional Chinese medicinal liquor has effects that reduce blood glucose, blood lipid and blood pressure.
Description
Technical field
The present invention relates to Traditional Chinese medicinal liquor technical field more particularly to a kind of Traditional Chinese medicinal liquors for improving antitumor immunity.
Background technique
Wine is known as the title of " length of hundred medicines ", and the Traditional Chinese medicinal liquor of the Chinese medicine to keep fit and healthy and wine " molten " Yu Yiti is not only matched
System is convenient, pharmacological property is stable, safely and effectively, and because alcohol is a kind of good semi-polarity organic solvent, the various of Chinese medicine have
Effect ingredient is all soluble in wherein, and wine assisting drug, wine help medicine gesture and gives full play to its effect, improves curative effect, but in the prior art
There are no the Traditional Chinese medicinal liquors that antitumor immunity can be improved.
Therefore a kind of Traditional Chinese medicinal liquor for improving antitumor immunity is proposed.
Summary of the invention
Technical problems based on background technology, the invention proposes a kind of Traditional Chinese medicinal liquors for improving antitumor immunity.
A kind of Traditional Chinese medicinal liquor improving antitumor immunity proposed by the present invention, including following raw medicinal material: matsutake, wheat meal
Stone, yellow wood, radix tetrastigme micro powder, mushroom, Radix Astragali, Radix Codonopsis and fructus lycii, it is preferable to use the mushroom of Wutai, Shanxi Province, mushrooms for mushroom
Son through processing be made lentinan powder, lentinan powder respectively the matsutake with radix tetrastigme micro powder, after milled processed,
Medical stone after milled processed, the mixing of the yellow wood after milled processed are dissolved in 450-550ml yellow rice wine, last Radix Astragali,
Radix Codonopsis and fructus lycii are immersed in 450-550ml yellow rice wine；
Preparation method includes the following steps:
S1: mushroom of selection is cleaned, and mushroom after cleaning is successively then carried out pulverization process and drying and processing,
Mushroom after finally drying carries out aether backflow ungrease treatment, obtains the sub- powder of mushroom；
The sub- powder of mushroom described in S1: being added in the water that 15-25 times is measured by S2 first, and the temperature setting of water is 45-55
DEG C, and the reaction time of the sub- powder of mushroom and water is set as 70-90min, and precipitating is then removed using active carbon decoloring, is obtained
Supernatant；
Ethyl alcohol is added in supernatant described in S3:S2, then carries out centrifugal treating, is precipitated, it is thick that this is precipitated as lentinan
Product；
Lentinan crude product described in S4:S3 is hydrolyzed first, then obtains lentinan fine work using chromatographic column；
The distilled water that lentinan fine work first passes around 350-450ml described in S5:S4 is tentatively eluted, and is then recycled
The phosphate buffer of 70-90ml carries out gradient elution, obtains lentinan powder；
S6: by matsutake, medical stone and yellow wood be utilized respectively pulverizer carry out pulverization process, then by matsutake, medical stone, yellow wood,
Lentinan powder described in radix tetrastigme micro powder and S5 is according to following weight mixed raw material: matsutake 6-10g, wheat meal
Stone is 2-4g, yellow wood 2.4-3.6g, radix tetrastigme micro powder 3.8-4.4g, lentinan powder are 40-60g；
Mixed raw material described in S7:S6 is dissolved into the yellow rice wine of 450-550ml, then by 45-55g Radix Astragali, 45-55g Radix Codonopsis
It is immersed in yellow rice wine with 45-55g fructus lycii, obtains Traditional Chinese medicinal liquor.
Preferably, in the S1, mushroom after cleaning carries out pulverization process using pulverizer.
Preferably, in the S1, smashed mushroom carries out drying and processing using drying equipment, and drying equipment is interior
Portion's temperature setting is 80-100 DEG C.
Preferably, in the S3, ethyl alcohol is the ethanol solution of 92-96% concentration.
Preferably, in the S3, centrifugal treating is carried out to the supernatant that ethyl alcohol is added using centrifugation apparatus.
Preferably, in the S4, chromatographic column is the chromatographic column of DEAE252 model, and chromatographic column utilizes the phosphate of pH518
Buffer is balanced, and lentinan crude product is dissolved in the upper prop of phosphate buffer.
Preferably, in the S7, mixed raw material is dissolved in the yellow rice wine of 450-550ml using mixing plant.
Beneficial effects of the present invention: yellow rice wine melts in yellow rice wine on the basis of the Traditional health cares material such as Radix Astragali, Radix Codonopsis and fructus lycii
Lentinan powder is entered, so that made Traditional Chinese medicinal liquor has effects that improve antitumor immunity, has in addition also been incorporated in yellow rice wine
Yellow wood, radix tetrastigme micro powder and medical stone, so that made Traditional Chinese medicinal liquor has effects that reduce blood glucose, blood lipid and blood pressure, this
Invention not only has effects that improve antitumor immunity, and has effects that reduce blood glucose, blood lipid and blood pressure.
Specific embodiment
Combined with specific embodiments below the present invention is made further to explain.
Embodiment one
A kind of Traditional Chinese medicinal liquor for improving antitumor immunity, including following raw medicinal material: matsutake, wheat meal are proposed in the present embodiment
Stone, yellow wood, radix tetrastigme micro powder, mushroom, Radix Astragali, Radix Codonopsis and fructus lycii, it is preferable to use the mushroom of Wutai, Shanxi Province, mushrooms for mushroom
Son through processing be made lentinan powder, lentinan powder respectively the matsutake with radix tetrastigme micro powder, after milled processed,
Medical stone after milled processed, the mixing of the yellow wood after milled processed are dissolved in 450ml yellow rice wine, last Radix Astragali, Radix Codonopsis
It is immersed in 450ml yellow rice wine with fructus lycii；
Preparation method includes the following steps:
S1: mushroom of selection is cleaned, and mushroom after then cleaning carries out pulverization process using pulverizer, after crushing
Mushroom carry out drying and processing using drying equipment, and the internal temperature of drying equipment is set as 80 DEG C, after finally drying
Mushroom carries out aether backflow ungrease treatment, obtains the sub- powder of mushroom；
The sub- powder of mushroom described in S1: being added in the water of 15 times of amounts by S2 first, and the temperature setting of water is 45 DEG C, and fragrant
The reaction time of mushroom powder and water is set as 70min, and precipitating is then removed using active carbon decoloring, obtains supernatant；
The ethanol solution of 92% concentration is added in supernatant described in S3:S2, then using centrifugation apparatus to the supernatant that ethyl alcohol is added
Liquid carries out centrifugal treating, is precipitated, this is precipitated as lentinan crude product；
Lentinan crude product described in S4:S3 is hydrolyzed first, then utilizes the chromatographic column of DEAE252 model, chromatographic column
It is balanced using the phosphate buffer of pH518, and lentinan crude product is dissolved in the upper prop of phosphate buffer, obtains perfume (or spice)
Mushroom polysaccharide products；
The distilled water that lentinan fine work first passes around 350ml described in S5:S4 is tentatively eluted, and 70ml is then recycled
Phosphate buffer carry out gradient elution, obtain lentinan powder；
S6: by matsutake, medical stone and yellow wood be utilized respectively pulverizer carry out pulverization process, then by matsutake, medical stone, yellow wood,
Lentinan powder described in radix tetrastigme micro powder and S5 is according to following weight mixed raw material: matsutake 6g, medical stone
It is 60g for 2g, yellow wood 2.4g, radix tetrastigme micro powder 3.8g, lentinan powder；
Mixed raw material described in S7:S6 is dissolved into the yellow rice wine of 450-550ml using mixing plant, then by 45g Radix Astragali,
45g Radix Codonopsis and 45g fructus lycii are immersed in yellow rice wine, obtain in Traditional Chinese medicinal liquor.
Embodiment two
A kind of Traditional Chinese medicinal liquor for improving antitumor immunity, including following raw medicinal material: matsutake, wheat meal are proposed in the present embodiment
Stone, yellow wood, radix tetrastigme micro powder, mushroom, Radix Astragali, Radix Codonopsis and fructus lycii, it is preferable to use the mushroom of Wutai, Shanxi Province, mushrooms for mushroom
Son through processing be made lentinan powder, lentinan powder respectively the matsutake with radix tetrastigme micro powder, after milled processed,
Medical stone after milled processed, the mixing of the yellow wood after milled processed are dissolved in 500ml yellow rice wine, last Radix Astragali, Radix Codonopsis
It is immersed in 500ml yellow rice wine with fructus lycii；
Preparation method includes the following steps:
S1: mushroom of selection is cleaned, and mushroom after then cleaning carries out pulverization process using pulverizer, after crushing
Mushroom carry out drying and processing using drying equipment, and the internal temperature of drying equipment is set as 90 DEG C, after finally drying
Mushroom carries out aether backflow ungrease treatment, obtains the sub- powder of mushroom；
The sub- powder of mushroom described in S1: being added in the water of 20 times of amounts by S2 first, and the temperature setting of water is 50 DEG C, and fragrant
The reaction time of mushroom powder and water is set as 80min, and precipitating is then removed using active carbon decoloring, obtains supernatant；
The ethanol solution of 94% concentration is added in supernatant described in S3:S2, then using centrifugation apparatus to the supernatant that ethyl alcohol is added
Liquid carries out centrifugal treating, is precipitated, this is precipitated as lentinan crude product；
Lentinan crude product described in S4:S3 is hydrolyzed first, then utilizes the chromatographic column of DEAE252 model, chromatographic column
It is balanced using the phosphate buffer of pH518, and lentinan crude product is dissolved in the upper prop of phosphate buffer, obtains perfume (or spice)
Mushroom polysaccharide products；
The distilled water that lentinan fine work first passes around 400ml described in S5:S4 is tentatively eluted, and 80ml is then recycled
Phosphate buffer carry out gradient elution, obtain lentinan powder；
S6: by matsutake, medical stone and yellow wood be utilized respectively pulverizer carry out pulverization process, then by matsutake, medical stone, yellow wood,
Lentinan powder described in radix tetrastigme micro powder and S5 is according to following weight mixed raw material: matsutake 8g, medical stone
It is 50g for 3g, yellow wood 3g, radix tetrastigme micro powder 4.1g, lentinan powder；
Mixed raw material described in S7:S6 is dissolved into the yellow rice wine of 500ml using mixing plant, then by 50g Radix Astragali, 50g party
Ginseng and 50g fructus lycii are immersed in yellow rice wine, obtain in Traditional Chinese medicinal liquor.
Embodiment three
A kind of Traditional Chinese medicinal liquor for improving antitumor immunity, including following raw medicinal material: matsutake, wheat meal are proposed in the present embodiment
Stone, yellow wood, radix tetrastigme micro powder, mushroom, Radix Astragali, Radix Codonopsis and fructus lycii, it is preferable to use the mushroom of Wutai, Shanxi Province, mushrooms for mushroom
Son through processing be made lentinan powder, lentinan powder respectively the matsutake with radix tetrastigme micro powder, after milled processed,
Medical stone after milled processed, the mixing of the yellow wood after milled processed are dissolved in 550ml yellow rice wine, last Radix Astragali, Radix Codonopsis
It is immersed in 550ml yellow rice wine with fructus lycii；
Preparation method includes the following steps:
S1: mushroom of selection is cleaned, and mushroom after then cleaning carries out pulverization process using pulverizer, after crushing
Mushroom carry out drying and processing using drying equipment, and the internal temperature of drying equipment is set as 100 DEG C, after finally drying
Mushroom carries out aether backflow ungrease treatment, obtains the sub- powder of mushroom；
The sub- powder of mushroom described in S1: being added in the water of 25 times of amounts by S2 first, and the temperature setting of water is 55 DEG C, and fragrant
The reaction time of mushroom powder and water is set as 90min, and precipitating is then removed using active carbon decoloring, obtains supernatant；
The ethanol solution of 96% concentration is added in supernatant described in S3:S2, then using centrifugation apparatus to the supernatant that ethyl alcohol is added
Liquid carries out centrifugal treating, is precipitated, this is precipitated as lentinan crude product；
Lentinan crude product described in S4:S3 is hydrolyzed first, then utilizes the chromatographic column of DEAE252 model, chromatographic column
It is balanced using the phosphate buffer of pH518, and lentinan crude product is dissolved in the upper prop of phosphate buffer, obtains perfume (or spice)
Mushroom polysaccharide products；
The distilled water that lentinan fine work first passes around 450ml described in S5:S4 is tentatively eluted, and 90ml is then recycled
Phosphate buffer carry out gradient elution, obtain lentinan powder；
S6: by matsutake, medical stone and yellow wood be utilized respectively pulverizer carry out pulverization process, then by matsutake, medical stone, yellow wood,
Lentinan powder described in radix tetrastigme micro powder and S5 is according to following weight mixed raw material: matsutake 10g, medical stone
It is 40g for 4g, yellow wood 3.6g, radix tetrastigme micro powder 4.4g, lentinan powder；
Mixed raw material described in S7:S6 is dissolved into the yellow rice wine of 550ml using mixing plant, then by 55g Radix Astragali, 55g party
Ginseng and 55g fructus lycii are immersed in yellow rice wine, obtain in Traditional Chinese medicinal liquor.
The Traditional Chinese medicinal liquor of the raising antitumor immunity of Traditional Chinese medicinal liquor and embodiment one to three is compared, embodiment one to three mentions
The raising percentage of the Traditional Chinese medicinal liquor of high antitumor immunity is as follows:
By above table it is found that the antitumor immunity performance of the Traditional Chinese medicinal liquor proposed by the present invention for improving antitumor immunity, drop blood
Sugared performance, reducing blood lipid performance and blood pressure lowering performance have obtained apparent improvement, and implementing two is most preferred embodiment.
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto,
Anyone skilled in the art in the technical scope disclosed by the present invention, according to the technique and scheme of the present invention and its
Inventive concept is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.
Claims (7)
1. a kind of Traditional Chinese medicinal liquor for improving antitumor immunity, which is characterized in that including following raw medicinal material: matsutake, medical stone, Huang
Mulberry, radix tetrastigme micro powder, mushroom, Radix Astragali, Radix Codonopsis and fructus lycii, it is preferable to use the mushroom of Wutai, Shanxi Province, mushroom warps for mushroom
Cross processing be made lentinan powder, lentinan powder respectively the matsutake with radix tetrastigme micro powder, after milled processed, pass through
Medical stone after milled processed, the mixing of the yellow wood after milled processed are dissolved in 450-550ml yellow rice wine, last Radix Astragali, Radix Codonopsis
It is immersed in 450-550ml yellow rice wine with fructus lycii；
Preparation method includes the following steps:
S1: mushroom of selection is cleaned, and mushroom after cleaning is successively then carried out pulverization process and drying and processing,
Mushroom after finally drying carries out aether backflow ungrease treatment, obtains the sub- powder of mushroom；
The sub- powder of mushroom described in S1: being added in the water that 15-25 times is measured by S2 first, and the temperature setting of water is 45-55
DEG C, and the reaction time of the sub- powder of mushroom and water is set as 70-90min, and precipitating is then removed using active carbon decoloring, is obtained
Supernatant；
Ethyl alcohol is added in supernatant described in S3:S2, then carries out centrifugal treating, is precipitated, it is thick that this is precipitated as lentinan
Product；
Lentinan crude product described in S4:S3 is hydrolyzed first, then obtains lentinan fine work using chromatographic column；
The distilled water that lentinan fine work first passes around 350-450ml described in S5:S4 is tentatively eluted, and is then recycled
The phosphate buffer of 70-90ml carries out gradient elution, obtains lentinan powder；
S6: by matsutake, medical stone and yellow wood be utilized respectively pulverizer carry out pulverization process, then by matsutake, medical stone, yellow wood,
Lentinan powder described in radix tetrastigme micro powder and S5 is according to following weight mixed raw material: matsutake 6-10g, wheat meal
Stone is 2-4g, yellow wood 2.4-3.6g, radix tetrastigme micro powder 3.8-4.4g, lentinan powder are 40-60g；
Mixed raw material described in S7:S6 is dissolved into the yellow rice wine of 450-550ml, then by 45-55g Radix Astragali, 45-55g Radix Codonopsis
It is immersed in yellow rice wine with 45-55g fructus lycii, obtains Traditional Chinese medicinal liquor.
2. a kind of Traditional Chinese medicinal liquor for improving antitumor immunity according to claim 1, which is characterized in that in the S1, clearly
Mushroom after washing carries out pulverization process using pulverizer.
3. a kind of Traditional Chinese medicinal liquor for improving antitumor immunity according to claim 1, which is characterized in that in the S1, powder
Mushroom after broken carries out drying and processing using drying equipment, and the internal temperature of drying equipment is set as 80-100 DEG C.
4. a kind of Traditional Chinese medicinal liquor for improving antitumor immunity according to claim 1, which is characterized in that in the S3, second
Alcohol is the ethanol solution of 92-96% concentration.
5. a kind of Traditional Chinese medicinal liquor for improving antitumor immunity according to claim 1, which is characterized in that in the S3, benefit
Centrifugal treating is carried out to the supernatant that ethyl alcohol is added with centrifugation apparatus.
6. a kind of Traditional Chinese medicinal liquor for improving antitumor immunity according to claim 1, which is characterized in that in the S4, layer
The chromatographic column that column is DEAE252 model is analysed, chromatographic column is balanced using the phosphate buffer of pH518, and lentinan is thick
Product are dissolved in the upper prop of phosphate buffer.
7. a kind of Traditional Chinese medicinal liquor for improving antitumor immunity according to claim 1, which is characterized in that in the S7, benefit
Mixed raw material is dissolved in the yellow rice wine of 450-550ml with mixing plant.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2589967A (en) * | 2019-10-29 | 2021-06-16 | Univ Shaanxi Technology | Chinese yellow rice wine containing ingredients of mulberry leaves (morus alba L.) and silkworm pupae (bombyx mori) and production method thereof |
| CN114507581A (en) * | 2022-03-11 | 2022-05-17 | 朱建国 | Preparation of radix tetrastigme health wine for enhancing immunity |
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| CN1742783A (en) * | 2004-08-30 | 2006-03-08 | 北京阜康仁生物制药科技有限公司 | Natural medicine preparatino for tonifying Qi strengthening body resistance and preparing method |
| CN101537081A (en) * | 2009-05-04 | 2009-09-23 | 郑友 | Matsutake health-care medicinal liquor with anticancer function and human body immunizing power enhancement function |
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2018
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| CN1742783A (en) * | 2004-08-30 | 2006-03-08 | 北京阜康仁生物制药科技有限公司 | Natural medicine preparatino for tonifying Qi strengthening body resistance and preparing method |
| CN101537081A (en) * | 2009-05-04 | 2009-09-23 | 郑友 | Matsutake health-care medicinal liquor with anticancer function and human body immunizing power enhancement function |
| CN105886288A (en) * | 2016-06-06 | 2016-08-24 | 孙立民 | Agaricus blazei murill healthcare liquor and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2589967A (en) * | 2019-10-29 | 2021-06-16 | Univ Shaanxi Technology | Chinese yellow rice wine containing ingredients of mulberry leaves (morus alba L.) and silkworm pupae (bombyx mori) and production method thereof |
| GB2589967B (en) * | 2019-10-29 | 2021-10-27 | Univ Shaanxi Technology | Chinese yellow rice wine containing ingredients of mulberry leaves (morus alba L.) and silkworm pupae (bombyx mori) and production method thereof |
| CN114507581A (en) * | 2022-03-11 | 2022-05-17 | 朱建国 | Preparation of radix tetrastigme health wine for enhancing immunity |
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Application publication date: 20190716 |