CN1190013A - Ointment for toothache and stomatocase - Google Patents
Ointment for toothache and stomatocase Download PDFInfo
- Publication number
- CN1190013A CN1190013A CN97118982A CN97118982A CN1190013A CN 1190013 A CN1190013 A CN 1190013A CN 97118982 A CN97118982 A CN 97118982A CN 97118982 A CN97118982 A CN 97118982A CN 1190013 A CN1190013 A CN 1190013A
- Authority
- CN
- China
- Prior art keywords
- parts
- ointment
- radix
- toothache
- stomatocase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 208000004371 toothache Diseases 0.000 title claims abstract description 13
- 239000002674 ointment Substances 0.000 title claims abstract description 9
- 239000003814 drug Substances 0.000 claims abstract description 25
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 9
- 235000010339 sodium tetraborate Nutrition 0.000 claims abstract description 8
- 229910021538 borax Inorganic materials 0.000 claims abstract description 6
- 239000004328 sodium tetraborate Substances 0.000 claims abstract description 6
- 229940079593 drug Drugs 0.000 claims description 11
- 239000007766 cera flava Substances 0.000 claims description 6
- 241000202807 Glycyrrhiza Species 0.000 claims description 2
- 239000000203 mixture Substances 0.000 abstract description 5
- 230000000694 effects Effects 0.000 abstract description 3
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 abstract 1
- 240000004670 Glycyrrhiza echinata Species 0.000 abstract 1
- 235000001453 Glycyrrhiza echinata Nutrition 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 235000017382 Glycyrrhiza lepidota Nutrition 0.000 abstract 1
- 244000299790 Rheum rhabarbarum Species 0.000 abstract 1
- 235000009411 Rheum rhabarbarum Nutrition 0.000 abstract 1
- 235000013871 bee wax Nutrition 0.000 abstract 1
- 239000012166 beeswax Substances 0.000 abstract 1
- 229940092738 beeswax Drugs 0.000 abstract 1
- 229940116229 borneol Drugs 0.000 abstract 1
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 abstract 1
- 229910052956 cinnabar Inorganic materials 0.000 abstract 1
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 abstract 1
- 229940010454 licorice Drugs 0.000 abstract 1
- 239000008159 sesame oil Substances 0.000 abstract 1
- 235000011803 sesame oil Nutrition 0.000 abstract 1
- 208000007117 Oral Ulcer Diseases 0.000 description 5
- 208000002399 aphthous stomatitis Diseases 0.000 description 5
- 208000002193 Pain Diseases 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- QQILFGKZUJYXGS-UHFFFAOYSA-N Indigo dye Chemical compound C1=CC=C2C(=O)C(C3=C(C4=CC=CC=C4N3)O)=NC2=C1 QQILFGKZUJYXGS-UHFFFAOYSA-N 0.000 description 2
- 241000283973 Oryctolagus cuniculus Species 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 239000006071 cream Substances 0.000 description 2
- 238000005469 granulation Methods 0.000 description 2
- 230000003179 granulation Effects 0.000 description 2
- 239000002085 irritant Substances 0.000 description 2
- 231100000021 irritant Toxicity 0.000 description 2
- 238000004137 mechanical activation Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000546 pharmaceutical excipient Substances 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 238000005303 weighing Methods 0.000 description 2
- -1 Calculus Bovis Chemical compound 0.000 description 1
- 235000005956 Cosmos caudatus Nutrition 0.000 description 1
- 244000293323 Cosmos caudatus Species 0.000 description 1
- 206010052359 Gingival abscess Diseases 0.000 description 1
- 241001165596 Hylotelephium erythrostictum Species 0.000 description 1
- 201000004328 Pulpitis Diseases 0.000 description 1
- 206010037464 Pulpitis dental Diseases 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 231100000215 acute (single dose) toxicity testing Toxicity 0.000 description 1
- 231100000403 acute toxicity Toxicity 0.000 description 1
- 230000007059 acute toxicity Effects 0.000 description 1
- 238000011047 acute toxicity test Methods 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 210000003038 endothelium Anatomy 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 229940037201 oris Drugs 0.000 description 1
- 201000001245 periodontitis Diseases 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 229910052957 realgar Inorganic materials 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 230000002618 waking effect Effects 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The ointment as one Chinese medicine composition is prepared with cinnabar, borax, Rhizoma Coptidis, rhubarb, Cortex Phellodendri, licorice, borneol, beeswax and sesame oil. It is used to cure toothache and stomatocase by being painted to affected part. It proved satisfactory in cure effect through clinical application.
Description
The present invention relates to a kind of Chinese medicine composition, particularly a kind of ointment for toothache and stomatocase.
Oral ulcer is commonly encountered diseases, the frequently-occurring disease in the disease of cari oris mucosa, and the patient suffering can't bear, but clinical active drug is less; The toothache that causes of a variety of causes also is one of clinical dentistry common sympton in addition, and before thoroughly being treated, toothache puzzlement patient is worried waking or sleeping.
" modern stomatology magazine " 1994 the 8th the 1st phases of volume have been reported " granulation promoting adheres to and looses ", add excipient by Chinese medicine Realgar, Indigo Naturalis, Calculus Bovis, Borneolum Syntheticum, Radix Sanguisorbae and form, and through topical application, obtain significant curative effect.
Chinese patent CN1097128A discloses " a kind of toothache pain relieving Chinese medicine composition ", be to add excipient composition by Fructus Zanthoxyli, Herba Asari, the Radix Angelicae Dahuricae, Radix Saposhnikoviae, Rhizoma Atractylodis, Radix Sophorae Flavescentis to form, can treat the pain that pulpitis, periodontitis, gingival abscess, toothache and postoperative cause.
Chinese patent CN1097999A discloses a kind of " treatment oral ulcer medication-Margarita Hylotelephium erythrostictum (Miq.) H.Ohba looses "; form by Margarita, Calculus Bovis, Borneolum Syntheticum, Endothelium Corneum Gigeriae Galli, Indigo Naturalis, Galla Chinensis, dried Alumen, Borax eight flavor Chinese prescriptions; control over one hundred routine patient through executing, achieve good results.
The objective of the invention is for a kind of externally-applied ointment of not only can only have a toothache but also can treat oral ulcer is provided.
The present invention is by following conceptual design.
The weight portion proportioning of composition of medicine of the present invention is:
Cinnabaris 8-12 part Borax 8-12 part
Rhizoma Coptidis 15-20 part Radix Et Rhizoma Rhei 13-15 part
Cortex Phellodendri 15-20 part Radix Glycyrrhizae 15-20 part
Borneolum Syntheticum 25-30 part Cera Flava 30-35 part
Oleum sesami 650-700 part.
Ideal weight portion proportioning is in the drug regimen of the present invention:
10 parts of 10 parts of Boraxs of Cinnabaris
15 parts of 15 parts of Radix Et Rhizoma Rhei of Rhizoma Coptidis
20 parts in 20 portions of Radix Glycyrrhizaes of Cortex Phellodendri
30 parts in 30 parts of Cera Flava of Borneolum Syntheticum
700 parts of Oleum sesami.
Preparation method of the present invention:
Take by weighing Chinese crude drug Rhizoma Coptidis, Cortex Phellodendri, Radix Et Rhizoma Rhei, Radix Glycyrrhizae, mechanical activation comminution, sieve, get fine powder and add Oleum sesami and boil, filter the back and add the Borneolum Syntheticum, Borax, Cinnabaris and the Cera Flava that grind to fine powder and fully stir evenly the back fill, natural cooling becomes cream, and is standby.
Low, the medicine source abundance of Zhi Bei medicine cost of the present invention like this, processing technique is simple, easy to use, can treat toothache and can treat oral ulcer again, and is safe and effective.
The using method of medicine of the present invention: medicine of the present invention is coated on toothache or oral ulcer affected part, every day 1-3 time.
Cure mainly: toothache, stomatocace.
Function: antiinflammatory, pain relieving, detoxifcation, granulation promoting.
Taboo: avoid pungent food during the medication.
Medicine of the present invention carries out its conclusion of irritant experiment through study of pharmacy chamber, Hebei province's medical courses in general institute Institute of Experimental Medicine:
Medicine of the present invention reacts rabbit skin nonirritant below 200mg dosage; Below 80mg dosage,, recovered normal, and be the reversibility irritant reaction therefore in 24 hours the only indivedual flare reactions of short duration of rabbit conjunctival.
Medicine acute toxicity test conclusion of the present invention is: under the oral situation of the Chinese medicine compound in the medicine of the present invention, and no acute toxicity performance, safer.
Medicine of the present invention is observed 45 examples through Xinji City, Hebei province second hospital clinical and is smeared medicine in the affected part, and wherein produce effects 21 examples account for 46.6%; 20 examples that take a turn for the better account for 44.4%; Invalid 4 examples account for 8.8%, and total effective rate reaches 91%.
Below in conjunction with embodiment it is described in the present invention.
Take by weighing choosing Chinese crude drug Rhizoma Coptidis, each 150 gram of Radix Et Rhizoma Rhei after whole, Cortex Phellodendri, each 200 gram of Radix Glycyrrhizae are crossed 400 mesh sieves after the mechanical activation comminution, to the greatest extent fine powder, in rustless steel container, add Oleum sesami 7000 grams, heated and boiled was got hospital gauze and is filtered after 1 hour.Other gets in Borneolum Syntheticum 300 grams, Cinnabaris 100 grams, Borax 100 grams and the Cera Flava 300 gram adding filtered liquid medicine of grinding to smalls, fully stirs evenly, and fill is in the no neck bottle that varies in size respectively, and natural cooling becomes cream, puts in storage standby.
Claims (2)
1. ointment for toothache and stomatocase is characterized in that this ointment is to be formed by the drug regimen that following weight is divided:
Cinnabaris 8-12 part Borax 8-12 part
Rhizoma Coptidis 15-20 part Radix Et Rhizoma Rhei 13-15 part
Cortex Phellodendri 15-20 part Radix Glycyrrhizae 15-20 part
Borneolum Syntheticum 25-30 part Cera Flava 30-35 part
Oleum sesami 650-700 part
2. ointment according to claim 1 is characterized in that ideal weight portion proportioning is in this ointment medicament combination:
10 parts of 10 parts of Boraxs of Cinnabaris
15 parts of 15 parts of Radix Et Rhizoma Rhei of Rhizoma Coptidis
20 parts in 20 portions of Radix Glycyrrhizaes of Cortex Phellodendri
30 parts in 30 parts of Cera Flava of Borneolum Syntheticum
700 parts of Oleum sesami
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN97118982A CN1061553C (en) | 1997-10-22 | 1997-10-22 | Ointment for toothache and stomatocase |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN97118982A CN1061553C (en) | 1997-10-22 | 1997-10-22 | Ointment for toothache and stomatocase |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1190013A true CN1190013A (en) | 1998-08-12 |
CN1061553C CN1061553C (en) | 2001-02-07 |
Family
ID=5175107
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN97118982A Expired - Fee Related CN1061553C (en) | 1997-10-22 | 1997-10-22 | Ointment for toothache and stomatocase |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN1061553C (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101185704B (en) * | 2007-12-11 | 2011-10-12 | 叶明华 | Powder agent medicine for treating aphtha |
CN110151563A (en) * | 2019-06-21 | 2019-08-23 | 山西医科大学口腔医院 | A kind of oral cavity reconciles cream and preparation method thereof |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100408065C (en) * | 2006-04-10 | 2008-08-06 | 赵军霖 | Chinese medicinal preparation for treating stomatocace and preparation method thereof |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1085100A (en) * | 1993-07-07 | 1994-04-13 | 冯文明 | A kind of specific tooth disease medicine |
CN1055856C (en) * | 1996-05-31 | 2000-08-30 | 王邦朗 | Medicine powder for stomatopathy and throat disease and its prepn process |
CN1157154A (en) * | 1996-12-25 | 1997-08-20 | 陆建东 | Traditional Chinese medicine preparation for curing toothache |
-
1997
- 1997-10-22 CN CN97118982A patent/CN1061553C/en not_active Expired - Fee Related
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101185704B (en) * | 2007-12-11 | 2011-10-12 | 叶明华 | Powder agent medicine for treating aphtha |
CN110151563A (en) * | 2019-06-21 | 2019-08-23 | 山西医科大学口腔医院 | A kind of oral cavity reconciles cream and preparation method thereof |
Also Published As
Publication number | Publication date |
---|---|
CN1061553C (en) | 2001-02-07 |
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PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C19 | Lapse of patent right due to non-payment of the annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |