CN118614508A - Insecticidal composition - Google Patents

Abstract

The invention relates to an insecticidal composition which contains an active ingredient of a compound shown in a formula I and a compound II, wherein the compound II is at least one selected from the group consisting of methomyl, isoprocarb, thiocyclam, cyantraniliprole, buprofezin, pymetrozine, dinotefuran, acetamiprid, thiacloprid, clothianidin, indoxacarb, abamectin, ivermectin, spirotetramat, sulfoxaflor, pyriproxyfen, diafenthiuron, bifenthrin and ethofenprox. The invention also relates to the use of the insecticidal composition for preventing or controlling pests of the aphididae, psyllidae, leafhopper, aleyrodidae and lecanidae families;

Description

Insecticidal composition

The application is a divisional application with the application number 202310210397.6 and the application date 2019, 6 and 25, and the name of the divisional application is an insecticidal composition; the parent case information of 202310210397.6 first division is: application number 201910553239.4, application date is 25 days of 2019, 6 months, and the application name is 'an insecticidal composition'.

Technical Field

The present invention relates to a pesticidal composition which is highly effective for controlling animal pests.

Background

The most typical problem in animal pest control is the need to reduce the dosage rate of the active ingredient to reduce or avoid adverse environmental or toxicological effects while still providing effective animal pest control effects.

Another difficulty with pest control is that repeated and unique use of a single pesticidal active ingredient in many cases results in a rapid selection of pests that produce natural or adaptive resistance to the active ingredient.

Due to the multiple generations and adaptation of the pests, the resistance of the pests is established in a relatively short time. There is also a need for pest control agents that have an effect on both pests and their larvae and eggs, which have superior penetration.

In addition, in pest control, there is also a need to combine knockdown activity with prolonged control time, i.e., rapid action and long-acting action.

The active ingredients of the formula I are known from WO2006/129714 and belong to Pyripropene derivatives.

Disclosure of Invention

It is an object of the present invention to provide a pesticidal composition which solves at least one of the problems such as improving biological properties, providing synergistic properties, lowering dose rates, expanding activity spectrum, combining knockdown activity with long acting effects, resistance management to delay resistance.

The present invention unexpectedly found that the combination of a compound of formula I with a compound II is effective in preventing or controlling animal pests and their larvae and eggs. Surprisingly, it has been found that the simultaneous (i.e., combined or separate) application of the active compounds of formula I and compound II or the sequential application of the compounds of formula I and compound II gives enhanced pest control effects compared to the possible control rates of the individual compounds, which unexpected effect is a true synergistic effect, not just the addition of the activities.

The invention relates to an insecticidal composition, which is realized by adopting the following technical scheme:

An insecticidal composition comprising the active ingredients of a compound of formula I and a compound II selected from one of the following compounds: the pesticide comprises the following components of methomyl, isoprocarb, thiocyclam, cyantraniliprole, buprofezin, pymetrozine, acetamiprid, thiacloprid, clothianidin, indoxacarb, abamectin, ivermectin, spirotetramat, sulfoxaflor, pyriproxyfen, dinotefuran, diafenthiuron, bifenthrin and ethofenprox.

The compound II is selected from the group consisting of methomyl and isoprocarb.

The compound II is selected from cyantraniliprole.

The compound II is selected from buprofezin.

The compound II is selected from pymetrozine.

The compound II is selected from acetamiprid, thiacloprid, clothianidin or dinotefuran.

The compound II is selected from indoxacarb.

The compound II is selected from the thiocyclam.

The compound II is selected from abamectin or ivermectin.

The compound II is selected from spirotetramat.

The compound II is selected from pyriproxyfen.

The compound II is selected from sulfoxaflor.

The compound II is selected from butyl ether urea.

The compound II is selected from bifenthrin or ethofenprox.

The weight ratio of the compound of formula I to the compound II is in the range of 10:1 to 1:150, preferably 1:5 to 1:150, preferably 1:10 to 1:100, more preferably 1:10 to 1:80, even more preferably 1:10 to 1:70, still more preferably 1:10 to 1:50, and a synergistic effect is obtained.

The weight ratio of the compounds of the formula I and the compounds of the formula II according to the invention can also be, for example 10:1,5:1,1:1,1:5,1:10、1:15、1:20、1:25、1:30、1:35、1:40、1:45、1:50、1:55、1:60、1:65、1:70、1:75、1:80、1:85、1:90、1:95、1:100、1:110、1:120、1:130、1:140、1:150.

An insecticidal composition comprising the active compounds of formula I and compound II, the weight of the compounds of formula I and compound II together comprising from 1% to 90%, preferably from 5% to 80%, more preferably from 5% to 70%, still more preferably from 5% to 60%, more preferably from 5% to 50% by weight of the insecticidal composition.

An insecticidal composition comprising the active compounds of formula I and compound II, the total weight of the compounds of formula I and compound II being the weight of the insecticidal composition and may be, for example 1%、2%、3%、4%、5%、6%、7%、8%、9%、10%、11%、12%、13%、14%、15%、16%、17%、18%、19%、20%、21%、22%、23%、24%、25%、26%、27%、28%、29%、30%、35%、40%、45%、50%、55%、60%、65%、70%、75%、80%、85%、90%.

An insecticidal composition comprising the active ingredients of a compound of formula I and a compound II, the insecticidal composition further comprising a surfactant and/or a filler.

The insecticidal composition is in the forms of emulsifiable concentrate, water suspending agent, oil suspending agent, seed treatment dry powder, seed treatment suspending agent, water dispersible granule, wettable powder, suspending agent, aerosol, coated granule, extruded granule, aqueous emulsion, microcapsule suspending agent, dry suspending agent, ultra-low volume liquid, electrostatic oil agent, gel, granule and microparticle.

The insecticidal compositions of the present invention may be applied undiluted or diluted with water.

The insecticidal composition of the present invention surprisingly exhibits extremely high activity in the treatment of plants, plant propagation material, soil in which plants are grown, for the prevention or control of pests and their larvae and eggs.

The insecticidal composition of the present invention has excellent control efficacy against pests and their larvae and eggs at low doses.

In another aspect, the invention also provides the use of a pesticidal composition for the prevention or control of pests and their larvae and eggs.

In particular, the invention provides the use of an insecticidal composition for preventing or controlling aphid, psyllidae, leafhopper, whitefly and mealybug pests.

More particularly, the invention provides a use of an insecticidal composition for preventing or controlling myzus persicae, cotton aphid, peach aphid, tea leafhopper, black tail leafhopper, white fly, pear psyllid, diaphorina citri, scale insect pest and larvae and eggs thereof.

The use of the insecticidal composition according to the invention for treating seed to prevent attack of the seed by pests.

The insecticidal composition of the present invention can be applied to seeds, plants or fruits of plants or soil where plants grow or soil suitable for plant growth.

In another aspect, the present invention also provides a method for preventing or controlling pests and their larvae and eggs, by applying the pesticidal composition of the present invention to a target useful plant, a target pest or a propagation material of an environment thereof, a target useful plant. The plant propagation material is a seedling, rootstock, nursery seedling, cutting or seed.

A method of preventing or controlling pests and their larvae and eggs by applying the pesticidal composition of the present invention to seeds, to a target useful plant or to soil in which the plant is growing or to soil suitable for plant growth.

A method of preventing or controlling pests and their larvae and eggs by applying the pesticidal composition of the present invention to soil before, after or before or after germination of seeds and/or directly to soil in contact with plant roots or soil suitable for plant growth.

A method of protecting seeds comprising contacting the seeds prior to sowing and/or after germination with a pesticidally effective amount of a pesticidal composition of the present invention.

The plants may be exemplified by: stem and leaf of plant, flower of plant, fruit of plant, etc.

The seed is selected from soybean, wheat, barley, rye, sorghum, peanut, sunflower, sugarcane, tobacco, rice, canola, kohlrabi, cabbage, beet, tomato, cowpea, carrot, cotton, and corn seeds.

A method of preventing or controlling pests comprising the separate, sequential or simultaneous application of a compound of formula I, compound II.

The pesticidal compositions of the present invention may be applied in any desired manner, such as seed coating, soil drenching and/or direct furrow application and/or foliar spray application, as well as pre-, post-, or pre-and post-emergence application.

The present invention provides an insecticidal composition comprising a compound of formula I and a compound II as active ingredients which addresses at least one of the problems of improving biological properties, providing synergistic properties, reducing dosage rates, expanding the spectrum of activity, combining knockdown activity with long-acting action, and resistance management to delay resistance. The combination of a compound of formula I with a compound II is effective in preventing or controlling animal pests and their larvae and eggs. The simultaneous (i.e., combined or separate) application of the active compounds of formula I and compound II or the sequential application of the compounds of formula I and compound II gives enhanced pest control effects compared to the possible control rates of the individual compounds, which unexpected effects are truly synergistic effects, not just additive effects of activity.

Detailed Description

To facilitate understanding of the present invention, examples are set forth below. It will be apparent to those skilled in the art that the examples are merely to aid in understanding the invention and are not to be construed as a specific limitation thereof.

The invention discovers that: the combination of the compounds of formula I and compound II is effective in preventing or controlling pests and their larvae and eggs. Surprisingly, the pesticidal compositions of the present invention have much higher activity in controlling pests than the sum of the properties of the active compounds alone. This unexpected effect is a true synergistic effect, not just the addition of the activities.

The term "synergistic" as used herein means that the insecticidal effect of the active compound combination or composition of the invention is greater than the sum of the effects of the individual active compounds, or that the effect is superadditive.

The invention provides an insecticidal composition which contains an active compound of a formula I and a compound II, wherein the compound II is selected from one of the following compounds: the pesticide comprises the following components of methomyl, isoprocarb, thiocyclam, cyantraniliprole, buprofezin, pymetrozine, acetamiprid, thiacloprid, clothianidin, indoxacarb, abamectin, ivermectin, spirotetramat, sulfoxaflor, pyriproxyfen, dinotefuran, diafenthiuron, bifenthrin and ethofenprox.

The insecticidal composition provided by the invention contains a compound shown in a formula I and methomyl or isoprocarb.

The insecticidal composition provided by the invention contains a compound shown in a formula I and abamectin or ivermectin.

The insecticidal composition disclosed by the invention contains a compound shown in a formula I and cyantraniliprole.

The insecticidal composition provided by the invention contains a compound shown in a formula I and sulfoxaflor.

The insecticidal composition provided by the invention contains a compound shown in a formula I and spirotetramat.

The insecticidal composition provided by the invention contains a compound shown in a formula I and thiocyclam.

The insecticidal composition disclosed by the invention contains a compound shown in a formula I and buprofezin.

The insecticidal composition provided by the invention contains a compound shown in the formula I, acetamiprid, thiacloprid, clothianidin and dinotefuran.

The insecticidal composition provided by the invention contains a compound shown in a formula I and pymetrozine.

The insecticidal composition disclosed by the invention contains a compound shown in a formula I and pyriproxyfen.

The insecticidal composition disclosed by the invention contains a compound shown in a formula I and diafenthiuron.

The insecticidal composition provided by the invention contains a compound shown in a formula I and bifenthrin or ethofenprox.

The weight ratio of the compound of formula I to the compound II is 10:1-1:150, preferably 1:5-1:150, preferably 1:10-1:100, more preferably 1:10-1:80, even more preferably 1:10-1:70, still more preferably 1:10-1:50.

The weight ratio of the compounds of the formula I and the compounds of the formula II according to the invention can also be, for example 10:1,5:1,1:1,1:5,1:10、1:15、1:20、1:25、1:30、1:35、1:40、1:45、1:50、1:55、1:60、1:65、1:70、1:75、1:80、1:85、1:90、1:95、1:100、1:110、1:120、1:130、1:140、1:150.

The preparation of compound II and its action on pests is known. Can be found in THE PESTICIDE Manual, 16 th edition and other publications.

The total amount of active ingredient in the insecticidal compositions of the present invention may be selected according to specific factors to achieve the desired effect. Such as dosage form, subject to be administered, method of administration, etc.

The invention provides an insecticidal composition which contains active compounds of formula I and compound II, wherein the total weight of the compounds of formula I and the compound II accounts for 1% -90%, preferably 5% -80%, more preferably 5% -70%, still more preferably 5% -60%, and more preferably 5% -50% of the weight of the composition.

An insecticidal composition comprising the active ingredients of a compound of formula I and a compound II, the weight of the compounds of formula I and the weight of the compounds II together being the weight of the insecticidal composition and may be, for example 1%、2%、3%、4%、5%、6%、7%、8%、9%、10%、11%、12%、13%、14%、15%、16%、17%、18%、19%、20%、21%、22%、23%、24%、25%、26%、27%、28%、29%、30%、35%、40%、45%、50%、55%、60%、65%、70%、75%、80%、85%、90%.

The insecticidal compositions of the present invention may optionally comprise an auxiliary ingredient such as an agronomically acceptable surfactant and/or filler. Preferably, the auxiliary ingredient is one or a mixture of dispersing agent, wetting agent, antifreeze agent, thickening agent, defoamer, disintegrant, binder and auxiliary carrier.

According to the present invention, the term "filler" refers to a natural or synthetic organic or inorganic compound that can be combined or associated with an active compound to make it easier to apply to a subject (e.g., plants, crops or grasses). Thus, the filler is preferably inert, at least should be agronomically acceptable. The filler may be solid or liquid.

The inactive filler that may be used in the present invention may be either solid or liquid.

Examples of solid fillers that can be used include: plant material powders (e.g., soybean powder, starch, grain powder, wood powder, bark powder, sawdust, walnut shell powder, bran, cellulose powder, coconut shells, corn cob and tobacco stem particles, residues after extraction of plant essence, etc.), clays (e.g., kaolin, bentonite, acidic porcelain clay, etc.), talc, silicas (e.g., diatomaceous earth, silica sand, mica, hydrous silicic acid, calcium silicate), activated carbon, natural minerals (pumice, attapulgite, zeolite, etc.), and burned diatomaceous earth.

As the liquid filler, there may be used, for example, water, isopropyl alcohol, butanol, ethylene glycol, propylene glycol, ethyl acetate, methyl oleate, amides, dimethyl sulfoxide, minerals, vegetable oil, etc.

Surfactants which can be used for emulsifying, dispersing, solubilizing and/or wetting the active ingredient compounds include, for example, fatty alcohol polyoxyethylene ethers, polyoxyethylene alkylaryl ethers, polyoxyethylene higher fatty acid esters, phosphoric acid esters of polyoxyethylene alcohols or phenols, fatty acid esters of polyhydric alcohols, naphthalene sulfonic acid polymers, lignin sulfonates, branched copolymers of high molecular combs, butylnaphthalene sulfonates, alkylaryl sulfonates, sodium alkylsulfosuccinates, oils and fats, condensates of fatty alcohols with ethylene oxide, polyacrylates of alkyl taurates, protein hydrolysates, suitable oligosaccharides or polymers, for example based on ethylene monomers, acrylic acid, polyoxyethylene and/or polyoxypropylene alone or in combination with, for example, (poly) alcohols or (poly) amines.

For dispersing, stabilizing and adhering the active ingredient compound, adjuvants such as xanthan gum, magnesium aluminum silicate, gelatin, starch, cellulose methyl ether, polyvinyl alcohol, polyvinyl acetate and natural phospholipids (e.g., cephalin and lecithin), synthetic phospholipids, bentonite, sodium lignin sulfonate and the like can be used.

Wherein the antifreezing agent can be selected from ethylene glycol, propylene glycol, glycerol, and sorbitol. As deflocculant for suspended products, adjuvants such as naphthalene sulfonic acid polymers, polymeric phosphates, and the like can be used. As the defoaming agent, a silicone defoaming agent can be used. For improving the flowability of the solid product, adjuvants such as paraffin, stearate, alkyl phosphate and the like can be used.

Colorants that may be used, for example, inorganic pigments such as iron oxide, titanium oxide, and Prussian blue; and organic pigments/dyes such as alizarin dyes, azo dyes and metal phthalocyanine dyes; and trace elements such as iron, manganese, boron, copper, cobalt, molybdenum and zinc salts.

Optionally, other additional components may also be included, such as protective colloids, binders, thickeners, thixotropic agents, penetrating agents, stabilizers, masking agents.

The pesticidal composition according to the present invention may be used as such or in the form of its formulation or use form prepared therefrom according to its respective physical and/or chemical properties, for example, aerosols, microcapsule suspensions, cold fogging agents, hot fogging agents, microcapsule granules, fine granules, suspension for seed treatment, ready-to-use solutions, powders, emulsifiable concentrates, oil-in-water emulsions, water-in-oil emulsions, macrogranules, microparticles, oil-dispersible powders, oil suspensions, oils, foams, pastes, seed coating agents, colloidal suspensions, suspension emulsions, aqueous solvents, suspending agents, wettable powders, soluble powders, powders and granules, water-soluble granules or tablets, water-soluble powders for seed treatment, wettable powders, natural products and synthetic substances impregnated with active ingredients, microcapsules in polymeric materials and seed-coated substances, and ultra-low volume cold fogging agents and hot fogging agents.

The preferred dosage forms of the insecticidal composition are emulsifiable concentrates, water suspending agents, oil suspending agents, seed treatment dry powder agents, seed treatment suspending agents, water dispersible granules, wettable powder agents, suspending agents, aerosol agents, coated granules, extruded granules, aqueous emulsion, microcapsule suspending agents, dry suspending agents, ultra-low volume liquid agents, electrostatic oil agents, gels, granules and microparticles.

The insecticidal compositions of the present invention may also be applied in combination with other active ingredients such as fungicides, bactericides, attractants, insecticides, acaricides, nematicides, growth regulators, herbicides, safeners, fertilizers or semiochemicals and the like.

The formulations according to the invention can be prepared by mixing the active ingredient with conventional additives in a known manner. Such as conventional extenders and solvents or diluents, emulsifiers, dispersants, and/or binders or fixatives, wetting agents, waterproofing agents, and if desired, siccatives and colorants, stabilizers, pigments, defoamers, preservatives, thickeners, water, and other processing aids.

The pesticidal composition of the present invention includes not only a concentrated commercial composition which is immediately applicable to a subject to be treated by means of a suitable apparatus such as a spraying or powdering apparatus, but also a concentrated commercial composition which is required to be diluted before application to the subject.

The insecticidal compositions of the present invention may be formulated for administration as a combination of the active ingredient compounds thereof, or as a combination of commercial preparations at appropriate dosages thereof.

The insecticidal composition of the invention has good plant compatibility and favorable isothermal animal toxicity, and is suitable for controlling harmful organisms encountered in the fields of agriculture, forestry, protection of stored products and materials and sanitation, in particular, the classes of insects (Insecta), arachnids (ARACHNIDA) and nematodes (Nematoda). They are active against species that are generally sensitive and resistant, and active against all or a single developmental stage, and also achieve the surprising "synergistic" effect of preventing or controlling pests.

The invention also provides a use of the insecticidal composition of the invention for preventing or controlling pests. The term "pest" is used herein to mean any organism that can cause a loss of the normal state of a plant. Including the insect pest class (Insecta), the arachnids (ARACHNIDA), the Nematoda class (Nematoda).

The class of insects includes lepidoptera, coleoptera, diptera, hemiptera, homoptera, hymenoptera, thysanoptera, isopoda, polyploid, cheilopoda, syndromism, thysanoptera, pachyrhizus, pinaster, orthoptera, blattaria, leather ptera, isoptera, louse.

Lepidopteran pests: the family of the borers (PYRALIDAE) such as Chilo suppressalis (chilosuppressalis (walker), triptera suppressalis (Tryporyzaincertulas (walker)), cnaphalocrocis medinalis (cnaphalocrocismedinalisGuenee), cabbage borer (hellullaundalis), pink-borer (conogethespunctiferlis), the family of the Pink-thread species (Pieridae) such as Pink cabbage (PIERIS RAPAE)), the family of the citrus ptera (papilioxuthus), the family of the white butterfly (pierisrapaecrucivora), the family of the Oryza sativa (parnaraguttata); lamp moth (ARCTIIDAE) such as fall webworm (hyphantriacunea); noctuidae (Noctuidae) such as noctuid (trichoplusiani), cabbage looper (mamestrabrassicae), beet armyworm (spodopteraexigua), prodenia litura (spodopteralitura), cotton bollworm (helicoverpaarmigera), armyworm (Pseudaletia separate), black cutworm (Agrotisipsilon); the Phantom (Tortricidae) is selected from the group consisting of Phantom tea (adoxophyesoranafasciata), phantom armeniaca (archipsfuscocureanus), phantom tea (homonamagnanima); plutellaceae (Plutellidae) such as plutella xylostella (plutellaxylotella); the family of the Fabry (GELECHIIDAE) such as pink bollworm (pectinophoragossypiella), red bollworm (Pink bollworm);

Coleopteran pests, such as: rice weevil (sitophilusoryzaelinne), citrus leaf miner (PodagricomelanigricollisChe), corn weevil (s.zeamail), grain weevil (s.granarius), great ape leaf worm (Cabbageleafbeetle), small ape leaf worm (Daikon leaf beele), flea beetle (fleabeetle), grape flea beetle (Alticachalybea), leaf beetle (phyllotretastriolata), cucumber flea beetle (Epitrixcucumeris), tobacco flea beetle (EHIRTIPENNIS), eggplant flea beetle (e.fulbulb), yellow cantaloupe (Aulacophoraindica (Gemlin), leaf beetle (Phaedoncochleariae), rice weevil (Lissorhoptrus oryzophilus), callosobruchuys chienensis, yellow meal worm (Tenebrio molitor), corn root beetle (Diabrotica VIRGIFERA VIRGIFERA), cucumber beetle (Diabrotica undecimpunctata howardi), tortoise (Anomala cuprea), red copper beetle (Anomala rufocuprea), yellow leaf beetle (Phyllotreta striolata), yellow melon (Aulacophora femoralis), potato beetle (Leptinotarsa decemlineata), rice beetle (Oulema oryzae), bostrychidae and longicoidae (Cerambycidae);

Dipteran pests, such as: rice leaf miner (agromyzaoryzae), barley leaf miner (hydrelliagriseola), gerbera leaf miner (liriomyzatrifolii), pea She Qianying (chromatomyiahorticola), tomato leaf miner (liriomyzabryoniae), gray ground seed fly (deliaplatura), shallot ground seed fly (deliaantiqua) Mediterranean fruit fly (CERATITISCAPIATAWIEDGMAN), apple fruit fly (Rhagoletispomonella), cherry fruit fly (r.

Hemipteran pests, for example: such as Aphis (APHIDIDAE), myzus (ADELGIDAE) or Rhizobiaceae (Phylloxeridae), such as Aphis tabaci (Myzus persicae), aphis gossypii (Aphis gossypii), aphis sojae (Aphis fabae), aphis zea (APHIS MAIDIS) (maize She Ya), aphis pis (Acyrthosiphon pisum), aphis solani (Aulacorthum solani), aphis faveolata (Aphis craccivora), aphis gossypii (P.faberi), The compound is prepared from the following raw materials of euphorbia lathyris (Macrosiphum euphorbiae), myzus persicae (Macrosiphum avenae), euonymus alatus (Metopolophium dirhodum), myzus gramineus Gu Yiguan (Rhopalosiphum padi), myzus gramineus (Schizaphis graminum), brassica oleracea (Brevicoryne brassicae), myzus persicae (LIPAPHIS ERYSIMI), spiraea ulpa (Aphis citricola), Rose apple aphid (Rosy APPLE APHID), aphis citricola (Eriosoma lanigerum), aphis citricola (Toxoptera aurantii) and Aphis citricola (Toxoptera citricidus), leafhopper (CICADELLIDAE), such as leafhopper (Nephotettix cincticeps); The family of planthoppers (DELPHACIDAE), such as Laodelphax striatellus (Laodelphax striatellus), brown planthopper (NILAPARVATA LUGENS), and sogatella furcifera (Sogatella furcifera); stinkbugs (Pentatomidae), such as, for example, white stinkbugs (Eysarcoris ventralis), green stinkbugs (Nezara viridula); whitefly (Aleyrodidae) such as Bemisia tabaci (Bemisia tabaci) and Bemisia tabaci (Trialeurodes vaporariorum); The compounds are selected from the group consisting of Lecanidae (DIASPIDIDAE), lecanidae (Margarodidae), lecanidae (Ortheziidae), ACLERDIAE, lecanidae (Dactylopiidae), lecanidae (Kerridae), lecanidae (Pseudocoddidae); ericeridae (Coccidae); ericeridae (Eriococcidae); lecaniaceae (Asterolecaniidae), lecaniaceae (Lecanodiaspididae); or the family of the pot (Cerococcidae), such as mealybugs of the Kangshi (Pseudococcus comstocki) and citrus mealybugs (Planococcus citri Risso); Psyllidae (PSYLLIDAE) such as pear psyllids (psyllapyrisuga), citrus psyllids (diaphorinatabaci);

Coleoptera (Coleoptera) pests such as weevil (Lissorhoptrus oryzophilus), callosobruchuys chienensis, yellow meal worm (Tenebrio molitor), corn rootworm (Diabrotica VIRGIFERA VIRGIFERA), cucumber beetle (Diabrotica undecimpunctata howardi), tortoise (Anomala cuprea), red copper beetle (Anomala rufocuprea), yellow stripe beetle (Phyllotreta striolata), yellow gecko (Aulacophora femoralis), potato beetle (Leptinotarsa decemlineata), rice negative mud worm (Oulema oryzae), bostrychidae and longicoidae (Cerambycidae);

Lepidoptera (Orthopteran) pests, such as the family of the locust (ACRIDIDAE); stinkbug (megacoptapunctatissimum), lygus lucorum (eurydemarugosum), white stinkbug (eysarcorislewisi), bai Xingchun (eysarcorisparvus), lygus lucorum (nezaraviridula), origanum vulgare (plautiastali), harpachyrhizus lucorum (halymorphamista), stinkbug (cletuspunctiger), stinkbug (leptocorisachinensis), azalea stinkbug (stephantispyrioides) and lygus erythrosepalae (trigonotyluscoelestialium).

Hymenoptera (hymenoptera) pests such as yellow wing cabbage wasp (athaliarosaeruficornis), rose wasp (argepagana), black mountain ant (formica japonica), chestnut gall wasp (dryocsmuskuriphilus) and the like.

The thysanoptera (Thysanopteran) pests, such as thrips palmi (THRIPS PALMI) and thrips frankliniella occidentalis (FRANKLINIELLA OCCIDENTALIS);

Isopoda (Isopoda), for example, capejasmine fruit water lice (Oniscusasellus), pillworm (Armadilliudiumvulgare), pillworm (Porcellioscaber).

The pests of the order of the genus bipedales, for example Blaniulusguttulatus.

The genus cheilopoda, e.g., the genus centipede (GeophiluscarpophagusScutigera spp.).

Pests of the order Symphytum, for example, white pine worms (Scutigerellaimmaculata).

Pests of the order thysanoptera, for example, tuna (LEPISMASACCHARINA).

The insect pests of the order of the warhead, for example, the army acanthus (Onychiurusarmatus).

The orthoptera pests, e.g., the family cricket (Achetadomesticus), the genus back, the species falcata (Gryllotalpa spp.), the species migratory locust asian (Locustamigratoriamigratorioides), the species black locust (Melanopluss pp.), the species desert locust (Schistocercagregaria).

The blattaria pests, for example, blatta orientalis (Blattaorientalis), periplaneta americana (PERIPLANETAAMERICANA), margaritifera (Leucophaeamaderae), blatta germanica (Blattellagermanica).

The pests of the order Dermaptera, for example, forficula auricularia (Forficulaauricularia).

Isopteran pests, for example, the species rotigotermes (roticulitermes spp.).

The order nites (Anoplura, PHTHIRAPTERA), such as, for example, beasts (DAMALINIA spp.), sanguinea (haemaPinusspp.), publice (Linognathus spp.), pedicellus (pedicellus spp.), and chewing lice (Trichodectes spp.).

The arachnidae (ARACHNIDA) are pests of the order acarina. Such as Panonychus citri (panonychuscitri), tetranychus cinnabarinus (Tetranychuscinnabarinus), panonychus ulmi (panonychusulmi), tetranychus urticae (tetranychusurticae), tetranychus (tetranychusviennensis), tetranychus (oligonychusununguis), panonychus citri (eotetranychuskankitus), short-haired mite (brevipalpusphoenicis), alfalfa moss mite (bryobiapraetiosa), tetranychus (aceriatulipae), grape goiter mite (colomerusvitis), tea goiter mite (calacaruscarinatus), yellow tea mite (polyphagotarsonemuslatus), long Mao Genman (rhizoglyphusrostochiensis), white iron mite (Acarussiro), citrus goiter mite (Aceriasheldoni), goiter shi (Aculusschlechtendali), tetranychus spp), panonychus (panoneichus spp), rugosa (Phyllocoptruta spp), and short-haired mite (Brevipalpus p).

Representative organisms of the class Nematoda (Nematoda)) are selected from the group consisting of Meloidogyne (Meloidogyne spp.), heterodera (Heterodera spp.), heterodera (Globodera spp.), perforin (radopholus spp.), brachyotus (Pratylenchus spp.), long-needle nematode (Longidorus spp.), and the like. Soybean cyst nematodes (hetodera), golden-potato nematodes (golboderarostochiensis), meloidogyne incognita (meloidogyne incognita) and the like are preferred.

In particular, the pesticidal compositions of the present invention are particularly effective in preventing or controlling "sucking" pests; these include in particular the following:

Aleyrodidae family: such as Bemisia tabaci (Aleurodes brassicae), bemisia tabaci (Bemisia tabaci), trialeurodes vaporariorum (Trialeurodes vaporariorum);

Aphididae family: such as Myzus persicae (Myzus persicae), cotton aphid (Aphis gossypii), cabbage aphid (Brevicoryne brassicae), green tea leaf cryptotaenia frontal aphid (Cryptomyzus ribis), broad bean aphid (Aphis fabae), apple aphid (Aphispomi), apple cotton aphid (Eriosoma lanigerum), peach tail aphid (Hyalopterusarundinis), grape root nodule aphid (Phylloxera vastatrix), wheat long tube aphid (Macrosiphum avenae), wheat long tube aphid (Macrosiphum avenae), wheat no net long tube aphid (Metopolophium dirhodum), cereal Gu Yiguan aphid (Rhopalosiphum padi), wheat binary aphid (Schizaphis graminum);

leafhoppers (CICADELLIDAE), such as black tail leafhoppers (Nephotettix cincticeps);

psyllidae (PSYLLIDAE) such as pear psyllids (psyllapyrisuga), and citrus psyllids (diaphorinatabaci).

General family of Lecanidae: the compounds are selected from the group consisting of Lecanidae (DIASPIDIDAE), lecanidae (Margarodidae), lecanidae (Ortheziidae), ACLERDIAE, lecanidae (Dactylopiidae), lecanidae (Kerridae), lecanidae (Pseudocoddidae); ericeridae (Coccidae); ericeridae (Eriococcidae); lecaniaceae (Asterolecaniidae), lecaniaceae (Lecanodiaspididae); or the family of the pot (Cerococcidae), such as mealybugs of the kansui family (Pseudococcus comstocki) and citrus mealybugs (Planococcus citri Risso);

In particular, the insecticidal compositions of the present invention exhibit an surprising "synergistic" effect on the prevention or control of aphididae, psyllidae, leafhopper, aleyrodidae, and lecanidae pests and their larvae and eggs.

The insecticidal composition of the invention surprisingly exhibits extremely high activity in the treatment of plants, plant propagation material, plant growth soil for the prevention or control of aphididae, psyllidae, leafhopper, whitefly, lecanidae pests and their larvae and eggs.

The insecticidal composition of the present invention has excellent control efficacy against aphididae, psyllidae, leafhopper, aleyrodidae, and lecanidae pests and their larvae and eggs at low doses.

In another aspect, the invention also provides the use of an insecticidal composition for preventing or controlling aphididae, psyllidae, leafhopper, aleyrodidae, and lecanidae pests and their larvae and eggs.

The invention provides an insecticidal composition for preventing or controlling myzus persicae, cotton aphid, peach aphid, tea leafhopper, black tail leafhopper, white fly in greenhouse, pear psyllid, diaphorina citri, scale insect pest and larva and ovum thereof.

The pesticidal composition of the present invention may be applied to any and all stages of development of pests, such as eggs, larvae, pupae and adults. Pests can be controlled by contacting the target pest, its food supply, habitat, breeding grounds or its locus with a pesticidally effective amount of the pesticidal composition of the present invention.

"Locus" refers to a plant, plant propagation material, soil, area, material or environment in which pests are growing or are likely to grow.

"Pesticidally effective amount" means the amount of the pesticidal composition of the present invention required to obtain an observable effect on growth, including death, prevention or removal effects, destructive effects or effects of reducing the appearance and activity of animal pests. The pesticidally effective amounts of the various pesticidal compositions used in the present invention may vary. The pesticidally effective amount of the composition will also vary depending upon the prevailing conditions such as desired pesticidal effect and duration, weather, target species, locus, mode of application, etc.

According to the invention, all plants and parts of plants can be treated. "plants" are understood here to mean all plants and plant populations such as desired and undesired wild plants or crops (including naturally occurring crops). The crop may be plants obtained by conventional breeding and optimization methods, or by biotechnological and genetic engineering methods or by combinations of these methods, including transgenic plants and plant cultivars including those which may or may not be protected by plant breeder certificates. Plant parts are understood to mean all above-and below-ground parts and plant organs such as seedlings, leaves, flowers and roots, examples which may be mentioned being leaves, needles, stems, flowers, fruit bodies, fruits and seeds and roots, tubers and rhizomes. Parts of plants also include post-harvest plants and vegetative and generative propagation material, such as seedlings, tubers, rhizomes, cuttings and seeds.

As described above, all plants and parts thereof can be treated according to the present invention. In a preferred embodiment, wild plant varieties and plant cultivars, or those obtained by conventional biological breeding methods such as crossing or protoplast fusion, and parts thereof, are treated. In a more preferred embodiment, transgenic plants and plant cultivars obtained by genetic engineering (optionally in combination with conventional methods (GENETICALLY MODIFIED ORGANISMS) and parts thereof) are treated.

According to the invention, it is particularly preferred to treat plants of plant cultivars which are in each case commercially available or in use.

The insecticidal composition according to the invention shows particularly advantageous effects when used for example in the following plants:

crops: corn, rice, wheat, barley, rye, oat, sorghum, cotton, soybean, peanut, buckwheat, beet, kohlrabi, cabbage, rapeseed, sunflower, sugarcane, tobacco, and the like.

Vegetables: solanaceae vegetables (eggplant, tomato, green pepper, chilli, potato, etc.), cucurbitaceae vegetables (cucumber, pumpkin, summer pumpkin, watermelon, melon, etc.), brassicaceous vegetables (rape, radish, turnip, horseradish, kohlrabi, cabbage, mustard, hard cauliflower, etc.), compositae vegetables (burdock, tarragon, artichoke, lettuce, etc.), liliaceae vegetables (onion, garlic, asparagus, etc.), umbelliferous vegetables (carrot, parsley, celery, parsnip, etc.), chenopodiaceae vegetables (spinach, lettuce, etc.), labiate vegetables (perilla, peppermint, basil, etc.), strawberry, sweet potato, taro, etc.

Fruit tree: pome fruits (apple, pear, japanese pear, papaya), stone fruits (peach, plum, nectarine, plum, yellow peach, apricot, prune, etc.), citrus fruits (citrus unshiu, orange, lemon, lime, grapefruit, etc.), nuts (chestnut, walnut, hazelnut, almond, cashew, etc.), berries (raspberry moss, blackberry), grape, persimmon, olive, loquat, banana, coffee, date palm, coconut, oil coconut, etc.

Trees other than fruit trees: tea, mulberry, flowering tree (azalea, camellia, hydrangea, camellia oleifera, japanese star anise, cherry, crape myrtle, cinnamomum cassia, etc.), street tree (birch, ginkgo, clove, maple, oak, poplar, cercis, sweetgum, syringwood, zelkova, japanese cypress, fir, japanese yew, juniper, pine, spruce, yew, elm, etc.), coral tree, himalayan, cedar, japanese cypress, croton, photinia serrulata, etc.

And (3) lawn: zoysia japonica (zoysia japonica, etc.), bermuda grass (bermuda grass, etc.), herba shoddy (megaly, creeping, dryland, etc.), bluegrass (prairie grass, bird grass, etc.), fescue (fescue, creeping red fescue, etc.), ryegrass (poison wheat, ryegrass, etc.), fescue, timothy grass, etc.

Other: flowers (rose, phyllostachys, chrysanthemum, platycodon grandiflorum, silk carnation, large-leaf clover, calendula, sage, petunia, verbena, tulip, gentian, lily, violet, cyclamen, orchid, bellflower, lavender, violet, kale, primula, euphorbia, daisy, orchid, begonia, etc.), biofuel plants (jatropha, safflower, camelina, switchgrass, miscanthus, reed, arundina, kenaf, cassava, willow, etc.), ornamental plants, and the like.

The insecticidal composition has good plant compatibility, and is suitable for controlling pests, especially insects, mites and nematodes, fungi, rodents, microorganisms and the like, and especially pests of Aphididae, phyllostachys, ezebra, bemisidae and Lecanidae. It is preferably applicable to foliar treatment, soil treatment and seed treatment.

In another aspect, the present invention also provides a method for preventing or controlling pests and their larvae and eggs, by applying the pesticidal composition of the present invention to a target useful plant, a target pest or a propagation material of an environment thereof, a target useful plant. It can be carried out before and after the plants, plant propagation material or the environment are infested with pests.

The term "plant propagation material" is understood to mean all plant parts, such as seeds, which are capable of reproductive capacity and which can be used for reproducing the latter, as well as plant materials such as cuttings or tubers (e.g. potatoes). Thus, plant parts as used herein include plant propagation material. Mention may be made, for example, of seeds, roots, fruits, tubers, bulbs, rhizomes and plant parts. Germinated plants to be germinated from soil or suppressed after emergence of seedlings, and effective plants. Young plants may be protected by impregnation, either entirely or partially, prior to implantation.

The plant propagation material is a seedling, rootstock, nursery seedling, cutting or seed. Seeds are preferred.

The insecticidal composition of the present invention can be applied to seeds, plants or fruits of plants or soil where plants grow or soil suitable for plant growth.

A method of protecting seeds comprising contacting the seeds prior to sowing and/or after germination with a pesticidally effective amount of a pesticidal composition of the present invention.

The plants may be exemplified by: stem and leaf of plant, flower of plant, fruit of plant, etc.

The seed is selected from soybean, wheat, barley, rye, sorghum, peanut, sunflower, sugarcane, tobacco, rice, canola, kohlrabi, cabbage, beet, tomato, cowpea, carrot, cotton, and corn seeds.

Accordingly, the present invention provides a method of protecting seeds, seedling roots and shoots from attack by soil and foliar insects comprising contacting the seeds with an effective amount of the insecticidal composition of the present invention prior to sowing and/or after pregermination.

The present invention also provides a method for controlling or preventing pests and their larvae and eggs in plant propagation material and plant organs, plant parts and/or plants grown thereafter, comprising applying the pesticidal composition of the present invention to the plant propagation material or its environment. The plant propagation material is preferably seeds.

Most damage to crop plants caused by pests occurs as early as the seeds, during storage and after the seeds are sown into the soil and during or after germination of the plants, when they are infested. This stage is particularly critical because the roots and shoots of the growing plant are particularly sensitive and even minor damage can lead to death of the whole plant. Thus, protection of seeds and germinated plants by the use of suitable compositions is of particular interest.

The invention also relates in particular to a method for protecting seeds and germinating plants from pests and their larvae and eggs by treating the seeds with the insecticidal composition according to the invention. The method of the present invention for protecting seeds and germinated plants from attack by psyllidae, phyllototaceae, leafhopper, whitefly, lecaniaceae pests and their larvae and eggs comprises a method of simultaneously treating the seeds with a compound of formula I and a compound of formula II. It also includes a method of treating the seed with a compound of formula I and a compound II at different times.

A method for preventing or controlling pests and their larvae and eggs, which comprises treating the seeds from which plants are expected to grow with a synergistically effective amount of the pesticidal composition of the present invention before sowing and/or after germination.

The invention also relates to the use of the insecticidal composition according to the invention for treating seeds to protect said seeds and plants growing therefrom from attack by pests and their larvae and eggs.

Furthermore, the present invention relates to seeds treated with the pesticidal composition of the present invention to obtain protection from pests and their larvae and eggs.

The invention also relates to seeds treated simultaneously with the compound of formula I and the compound II. The invention also relates to seeds treated with a compound of formula I and a compound II at different times. For seeds treated with the compound of formula I and compound II at different times, the individual active compounds of the insecticidal compositions of the present invention may be present in different layers on the seed. Wherein the layers comprising the compound of formula I and the compound II may optionally be separated by an intermediate layer. The invention also relates to seeds in which the compounds of formula I and the compounds II are applied as coating components or as one or more additional layers outside the coating.

The pesticidal composition of the present invention may be applied to seeds of any physiological state. Preferably the seeds are in a sufficiently durable state so as not to be damaged during the treatment process. In general, the seed may be seed harvested from the field, removed from the plant, isolated from any cobs, stems, husks and surrounding pulp or other non-seed plant material. The seed may also preferably be biologically stable to the extent that the treatment does not cause biological damage to the seed. The application to the seeds may be treated at any time between seed harvest and seed sowing or during the sowing process. The seeds may also be germinated before or after treatment.

Seeds treated with the insecticidal composition of the present invention can be stored, managed, sown and cultivated.

Seed treatment can be accomplished by applying the compound of formula I and isoprocarb or methomyl thereto in any desired sequence or simultaneously.

Seed treatment occurs on unsown seeds, the term "unsown seeds" is intended to include seeds that are sown in the ground for any period between the time of seed harvest and the time of seed germination and growth of the plant. Preferably, the treatment occurs before sowing the seeds, whereby the sowing seeds have been pre-treated with the combination. In particular, seed coating or seed pelleting is preferred in the treatment of the combination of the invention. After treatment, the components of each combination adhere to the seed and are therefore useful for pest control.

Seed treatment methods include all methods known to those skilled in the art as suitable for treating seeds, such as seed dressing, seed coating, seed soaking, seed coating, seed multilayer coating, seed soaking, seed dusting, and seed pelleting.

The composition of the present invention may be applied to seeds, plants or fruits of plants or soil where plants are grown or soil suitable for plant growth.

The present invention also provides a method for preventing or controlling pests and their larvae and eggs, comprising applying the pesticidal composition of the present invention to seeds, to a target useful plant or to soil in which plants are grown or to soil suitable for plant growth.

In another aspect, the present invention also provides a method for preventing or controlling pests and their larvae and eggs by applying the pesticidal composition of the present invention to soil before, after or before or after germination of seeds and/or directly to soil in contact with plant roots or soil suitable for plant growth.

The present invention also provides a method of protecting plants from attack by pests and their larvae and eggs, comprising applying the pesticidal composition of the present invention to the environment, habitat or storage area in which the useful plants are grown. The environment and habitat of plant growth refer to a support body capable of rooting and growing crops, for example: soil, water, etc., concrete raw materials may be, for example, sand, pumice, vermiculite, diatomaceous earth, agar, gel-like substance, polymer substance, asbestos, wood chips, bark, etc. Soil is preferred.

The invention also provides a method of protecting plants from infestation by psyllidae, phyllototaceae, leafhopper, whitefly, lecanidae pests and their larvae and eggs, comprising the combined, separate or sequential application of the active ingredients of the compounds of formula I and of the compounds II. In the case of separate applications, the sequence generally has no influence on the result of the control measures.

A method for preventing or controlling pests and their larvae and eggs comprising the separate, sequential or simultaneous administration of a compound of formula I, compound II.

The present invention also provides a method of protecting a useful plant from attack by pests and their larvae and eggs, which comprises applying a combination comprising a compound of formula I and a compound II, in any desired order or simultaneously, on the target useful plant or its environment, the target pest or its environment, the propagation material of the target useful plant.

The insecticidal compositions of the present invention include not only ready-to-use compositions that can be applied to plants or plant propagation material with a suitable device, but also commercial concentrates that must be diluted with water prior to application.

The insecticidal compositions of the present invention may be applied undiluted or diluted with water.

The present invention provides a method for preventing or controlling pests and their larvae and eggs by applying the pesticidal composition of the present invention to a target useful plant or its environment, to propagation material of the target useful plant, other pesticides being able to be applied simultaneously with or separately from the application of the compounds of formula I and compound II, and in the case of separate application of the compounds of formula I and compound II, each other pesticide being able to be applied simultaneously with, between or after the application of the compounds of formula I and compound II.

It is common and advantageous for the pesticidal composition of the present invention to be applied generally in the following doses:

For foliar treatment: 0.1 to 10000g/ha, preferably 10 to 1000g/ha, more preferably 10 to 300g/ha, still more preferably 10 to 500g/ha;

For seed treatment: 1-1000g/100kg seed, preferably 100-1000g/100kg seed;

For soil treatment: 1-10000g/ha, preferably 10-1000g/ha.

The above dosages are merely exemplary dosages in general, and the person skilled in the art will adapt the application rate to the actual situation and need, especially according to the nature of the plant or crop to be treated and the pest situation, at the time of actual application.

Methods of treating target pests, target useful plants, or seeds, soil with the pesticidal composition of the present invention include, for example, spreading treatment, soil treatment, surface treatment, and fumigation treatment. Spreading treatments include, for example, spreading, spraying, atomizing, and particle application. Soil treatment includes, for example, soil irrigation and soil mixing. Surface treatments include, for example, coating and covering. Fumigation treatment includes, for example, covering the soil with polyethylene film after injection into the soil.

The pesticidal composition of the present invention is typically applied by the applicator to a backpack sprayer, spray can, spray aircraft or irrigation system. The insecticidal compositions of the present invention are typically formulated with water, buffers and/or other adjuvants to the desired application concentration to provide a ready-to-use spray.

Compared with the prior art, the invention has at least the following beneficial effects:

(1) The pesticidal composition of the present invention may show synergistic activity compared to the activity of the compound alone;

(2) The insecticidal composition of the present invention treats plants and plant propagation materials to a level that represents a significant improvement;

(3) The pesticidal composition of the present invention reduces infestation and attack by any undesired pests and their larvae and eggs; in particular, the aphididae, psyllidae, leafhopper, aleyrodidae, and the lecanidae pests and their larvae and eggs;

(4) The invention mixes the compound of the formula I and the compound II, solves the problems of lasting effect and quick acting property, thereby reducing the times of medicine application and lowering the labor cost;

(5) The insecticidal composition of the present invention delays the development of resistance: the two have completely different action mechanisms and action modes, and have the effects of contact killing, stomach poisoning, egg killing and egg laying rate and hatching rate reduction after combination, so that pests are more easily killed, and the generation of resistance is delayed;

(6) The insecticidal composition of the present invention exhibits high efficiency, thus reducing the dosage rate and reducing the load on the environment;

(7) The insecticidal compositions of the present invention may also be used for post-harvest protection.

Formulation examples

EXAMPLE 1 wettable powder

5% Of the compound of formula I

Fast carbofuran 20%

Calcium lignosulfonate 4%

Sodium lauryl sulfate 1%

The kaolin is complemented to 100%

Mixing the above components in proportion, grinding and pulverizing to obtain wettable powder.

EXAMPLE 2 wettable powder

5% Of the compound of formula I

Cyantraniliprole 10%

Sodium dodecyl sulfate 5%

Sodium lignin sulfonate 2%

The diatomite is complemented to 100%

Mixing the above components in proportion, grinding and pulverizing to obtain wettable powder.

EXAMPLE 3 dispersible oil suspension

5% Of the compound of formula I

Spirotetramat 20%

Fatty acid polyoxyethylene ether 5%

Modified lignin sodium sulfate 5%

1% Of organic bentonite

The soybean oil is complemented to 100%

The active components, the dispersing agent, the wetting agent, the oil and the like are uniformly mixed according to the proportion of the formula, and the oil suspending agent is obtained after grinding and/or high-speed shearing.

Example 4 emulsifiable concentrate

0.5% Of the compound of formula I

Isoprocarb 25%

Ethoxylated castor oil 3%

Calcium dodecylbenzenesulfonate 2%

N, N-dimethylformamide 30%

SOLVESSO 200 is complemented to 100%

The above components are uniformly mixed and dissolved to obtain the emulsifiable concentrate.

Example 5 emulsifiable concentrate

Compounds of formula I1%

Buprofezin 15%

Ethoxylated castor oil 3%

Calcium dodecylbenzenesulfonate 2%

N, N-dimethylformamide 15%

SOLVESSO 200 is complemented to 100%

The above components are uniformly mixed and dissolved to obtain the emulsifiable concentrate.

Example 5 Water dispersible granule

Compounds of formula I1%

Isoprocarb 50%

Modified sodium lignin sulfonate 2%

Sodium dodecyl sulfate 2%

Clay 1%

Uniformly mixing and grinding the components, adding a certain amount of water, mixing, extruding and making materials, and drying and screening to obtain the water dispersible granule.

EXAMPLE 6 aqueous suspension

5% Of the compound of formula I

Diafenthiuron 30%

Sodium lignin sulfate 10%

1% Aqueous xanthan gum solution 1%

Bentonite 1.5%

Glycerol 5%

Water make up to 100%

The components are uniformly mixed according to the proportion of the formula, and the water suspending agent is obtained after grinding and/or high-speed shearing.

Example 7 suspoemulsion

Compounds of formula I1%

Isoprocarb 25%

Dimethylformamide 25%

Ethoxylated castor oil 4%

Polystyrene phenyl ether sulfate 5%

Modified calcium lignosulfonate 3%

1% Aqueous xanthan gum solution 1%

Bentonite 1%

Glycerol 3%

Water make up to 100%

Dissolving the isoprocarb in dimethylformamide, and adding ethoxylated castor oil to obtain the emulsifiable concentrate of the isoprocarb.

Uniformly mixing a compound of the formula I, polystyrene phenyl ether sulfate, modified calcium lignosulfonate and water according to a proportion, and performing sand grinding to obtain a mixture; then, adding 1% xanthan gum aqueous solution, glycerol and bentonite into the sanded mixture to prepare the suspending agent containing the compound of the formula I.

Adding the oil phase containing the isoprocarb into the suspending agent containing the compound of the formula I to obtain the suspoemulsion.

Example 8 suspoemulsion

5% Of the compound of formula I

Avermectin 1%

SOLVESSO200 20%

Ethoxylated castor oil 3%

Sodium lignin sulfate 6%

1% Aqueous xanthan gum solution 1%

Bentonite 1%

Glycerol 3%

Water make up to 100%

Dissolving avermectin in SOLVESSO200, and adding ethoxylated castor oil to obtain avermectin emulsifiable concentrate.

Uniformly mixing a compound of the formula I, sodium lignin sulfate and water in proportion, and performing sand grinding to obtain a mixture; then, adding 1% xanthan gum aqueous solution, glycerol and bentonite into the sanded mixture to prepare the suspending agent containing the compound of the formula I.

And adding the avermectin-containing oil phase into a suspending agent containing the compound shown in the formula I to obtain the suspension emulsion.

The proportion of the above embodiments is weight percentage.

Biological test case

The intended effect of a particular combination of two active ingredients may be calculated using the so-called "Colby formula" (see S.R. Colby, "Calculating Synergistic and Antagonistic Responses of HerbicideCombinations ",Weeds 1967,15, 20-22) :

x is the control effect when using an active ingredient of the formula I in an amount of m g/ha or at a concentration of m ppm, expressed as a percentage of untreated control,

Y is the control effect when using an active ingredient compound II in an amount of n g/ha or at a concentration of n ppm, expressed as a percentage of untreated control,

E is the control effect when using the active ingredients of the formula I and of the formula II in amounts of m and n g/ha or in concentrations of m and n ppm, expressed as a percentage of untreated control,

If the actual control effect exceeds the calculated value, the lethal effect of the composition is super-additive, i.e., there is a synergistic effect.

Test example 1 cabbage aphid test

Preparing a liquid medicine: the stock solution of the compound of formula I (synthesized by the method described in WO 2006/129714) and the stock solution of the compound II (commercially available) in Table 1 (commercially available) were each dissolved in acetone to prepare a single preparation, and diluted to the desired concentration with an aqueous solution containing 0.1% Tween-80.

The method comprises the steps of taking the green peach aphids (Myzus persicae Sulzer) as tested pests, picking up cabbage vegetable fields in the Jiangsu Kunshan test lands, and selecting 30 green peach aphids with similar body colors and uniform sizes as a group for indoor test after breeding one generation on insect-free cabbages planted in an insect-proof net room.

Soaking aphid and cabbage leaf in the prepared medicinal liquid for 10 s, taking out, sucking excessive medicinal liquid with absorbent paper, and placing into plastic beaker with diameter of 6cm and height of 10 cm. After the test is finished, the mixture is transferred to a constant temperature incubator with the relative humidity of 25+/-2 ^o ℃ and the relative humidity of 60% -80% for feeding. Control treatments a blank was made with the treatment without agent. The test results were checked by the agent treatment for 72 h. If the control mortality rate is greater than 20%, the test is reworked.

The calculation method comprises the following steps:

Mortality (%) = (number of live insects before drug-number of live insects after drug)/number of live insects before drug x 100

Control effect% = ((treatment group mortality-control group mortality)/(100-control group mortality)) ×100

Table 1 test of combinations of Compounds of formula I and Compound II on the green peach aphid

Test example 2 tomato Bemisia tabaci test

Preparing a liquid medicine: the compound of formula I (synthesized by the method described in WO 2006/129714), the compound II (commercially available) in Table 2, were dissolved in acetone to prepare a single-dose mother liquor, which was then diluted to the desired concentration with an aqueous solution containing 0.1% Tween-80.

Bemisia tabaci is supplied by eastern village farm farming, a company of junsu tornado chemistry, and has no obvious resistance. Before the test, the bemisia tabaci is inoculated on greenhouse potted insect-free tomato seedlings (variety: delphinidia chinensis) planted in the insect-proof net room. When the eggs are hatched and developed to F1 generation 2-3 years old nymphs, cutting tomato leaves, microscopic examining and removing non-test insect states such as insect eggs, wherein each leaf of test nymphs is 30, and the test nymphs are ready for testing.

The bemisia tabaci and the tomato leaves are soaked in the prepared liquid medicine for 5 seconds, taken out, the excessive liquid medicine is sucked by the water absorbing paper, and the liquid medicine is placed in a plastic beaker with the diameter of 6cm and the height of 10 cm. After the test is finished, the mixture is transferred to a constant temperature incubator with the relative humidity of 25+/-2 ^o ℃ and the relative humidity of 60% -80% for feeding. Control treatments a blank was made with the treatment without agent. 72 hours after treatment, the test insects were examined under a microscope for mortality. And judging the death standard as that the insect body is shrunken and the color becomes withered and yellow.

If the control mortality rate is greater than 20%, the test is reworked.

The calculation method comprises the following steps:

Mortality (%) = (number of live insects before drug-number of live insects after drug)/number of live insects before drug x 100

Control effect% = ((treatment group mortality-control group mortality)/(100-control group mortality)) ×100

Table 2 test of combinations of compounds of formula I and compound II on tomato bemisia tabaci

Test example 3 test of a combination of Compounds of formula I and Compound II on tea leafhoppers

Preparing a liquid medicine: the compound of formula I (synthesized by the method described in WO 2006/129714), the compound II (commercially available) in Table 3, were dissolved in acetone to prepare a single-dose mother liquor, which was then diluted to the desired concentration with an aqueous solution containing 0.1% Tween-80.

Tea leafhoppers have no indoor feeding strain. The test collects tender tea leaves of tea trees, which are seriously damaged by leafhoppers, from a Zhejiang tea field nursery base, and brings the tender tea leaves back to a laboratory, and the test belongs to a composite population and takes tea leafhoppers (Empoasca flavescens Fabr) as a relatively dominant species. In this test, tea leafhoppers were used as subjects. Selecting tea leafhoppers, feeding potted tea trees in insect-raising cages, and taking F1 generation 3-year nymphs for test. Each group of experiments selected 20 healthy and active tea leafhoppers with basically consistent sizes.

Immersing tea leaves with 3-year nymphs of the tea leafhoppers to be tested in the liquid medicine, taking out after 10S, sucking the obvious excessive liquid medicine occupied by the test insects by using the filtrate, transferring the liquid medicine to fresh and nontoxic tender tea leaves, keeping the leaf stalks moist by using a moist cotton ball, placing the leaves in a culture glass jar, covering tightly, covering with a perforated cover, wrapping with gauze, and keeping air circulation. After the test is finished, the mixture is transferred to a constant temperature incubator with the relative humidity of 25+/-2 ^o ℃ and the relative humidity of 60% -80% for feeding. Control treatments a blank was made with the treatment without agent. 24 hours after treatment, the death of the test insects was investigated. The death standard of the tea lesser leafhopper nymphs is judged to be that the insect bodies shrink obviously, and no obvious crawling exists when the insect needles are touched lightly. Total number of insects and number of dead insects were recorded. And calculating the death rate and the prevention and treatment effect. If the control mortality rate is greater than 20%, the test is reworked.

The calculation method comprises the following steps:

Mortality (%) = (number of live insects before drug-number of live insects after drug)/number of live insects before drug x 100

Control effect% = ((treatment group mortality-control group mortality)/(100-control group mortality)) ×100

TABLE 3 test of combinations of Compounds of formula I and Compound II on tea leafhoppers

Test example 4 test of diaphorina citri

Preparing a liquid medicine: the compound of formula I (synthesized by the method described in WO 2006/129714), compound II in Table 4 (commercially available) were dissolved in acetone to prepare a single-dose mother liquor, which was diluted to the desired concentration with an aqueous solution containing 0.1% Tween-80.

The test insect is diaphorina citri (Diaphorina citri kuwayama). There is no indoor breeding line. In the test, branches with a large number of citrus psyllids are collected from sugar orange trees planted in a Guangxi-Lin Mou citrus orchard, the rest insect states are removed by a No. flexible writing brush in a laboratory, and only adults are left for testing. The citrus trees in the test insect source were not applied with any pesticides and fertilizers for at least one year.

Soaking fresh and tender citrus leaf with insects collected from insect source land in test liquid, taking out after 5S, air drying, placing in a culture jar, moistening the petiole with wet cotton, spreading moistening filter paper on the bottom of the culture jar, and covering with vent holes. Each group of experiments selects 15 test insects.

After the test is finished, the mixture is transferred to a constant temperature incubator with the relative humidity of 25+/-2 ^o ℃ and the relative humidity of 60% -80% for feeding. Control treatments a blank was made with the treatment without agent. 24 hours after treatment, the death of the test insects was investigated. The death standard of the adult diaphorina citri is judged to be that the insect body is obviously contracted, and no obvious climbing occurs when the insect needle is touched lightly. Total number of insects and number of dead insects were recorded. And calculating the death rate and the prevention and treatment effect. If the control mortality rate is greater than 20%, the test is reworked.

The calculation method comprises the following steps:

Mortality (%) = (number of live insects before drug-number of live insects after drug)/number of live insects before drug x 100

Control effect% = ((treatment group mortality-control group mortality)/(100-control group mortality)) ×100

TABLE 4 control of diaphorina citri by combinations of compounds of formula I and compound II

Test example 5 test of scale insects

Preparing a liquid medicine: the compound of formula I (synthesized by the method described in WO 2006/129714), and the crude compound II (commercially available) in Table 5 were dissolved in acetone to prepare a single-dose mother liquor, which was then diluted to the desired concentration with an aqueous solution containing 0.1% Tween-80.

Scale insects (Pseudococcus comstocki)) are used as test pests. The perennial vermilion breeds (25 ^o C,14 h) were used. The nymphs were selected for testing with the same breeding in the room. 100 test insects were selected for each set of experiments.

The dipping method is adopted. Cutting leaf segments of Cinnamomum zeylanicum which infest the scale insects into leaf segments with the length of about 1cm, and soaking the leaf segments in the liquid medicine for 10S. Culturing on wet cotton. After the test is finished, the mixture is transferred to a constant temperature incubator with the relative humidity of 25+/-2 ^o ℃ and the relative humidity of 60% -80% for feeding. Control treatments a blank was made with the treatment without agent. 72 hours after treatment, the death of the test insects was investigated. Under the dissecting scope, the light touch non-response was considered dead worm. And calculating the death rate and the prevention and treatment effect. If the control mortality rate is greater than 20%, the test is reworked.

The calculation method comprises the following steps:

Mortality (%) = (number of live insects before drug-number of live insects after drug)/number of live insects before drug x 100

Control effect% = ((treatment group mortality-control group mortality)/(100-control group mortality)) ×100

TABLE 5 control of scale insects by combinations of Compounds of formula I and Compound II

The test results in tables 1-5 show that the combination of compounds of formula I and compound II provides a synergistic effect on control of cabbage aphids, tomato bemisia tabaci, tea leafhoppers, citrus psyllids, and scale insects.

Claims (19)

1. An insecticidal composition comprising the active ingredients of a compound of formula I and a compound II:

Chemical formula I

；

The compound II is selected from the thiocyclam, and the weight ratio of the compound of the formula I to the compound II is 10:1-1:150.

2. The insecticidal composition according to claim 1 wherein the weight ratio of the compound of formula I to the compound of formula II is from 1:5 to 1:150.

3. The insecticidal composition according to claim 1 wherein the weight ratio of the compound of formula I to the compound of formula II is 1:10 to 1:150.

4. The insecticidal composition according to claim 1 wherein the weight ratio of the compound of formula I to the compound of formula II is 1:10 to 1:100.

5. The insecticidal composition according to claim 1 wherein the weight ratio of the compound of formula I to the compound of formula II is 1:10 to 1:80.

6. The insecticidal composition according to claim 1 wherein the weight ratio of the compound of formula I to the compound of formula II is 1:10 to 1:70.

7. The insecticidal composition according to claim 1 wherein the weight ratio of the compound of formula I to the compound of formula II is 1:10 to 1:50.

8. The insecticidal composition of claim 1, further comprising a surfactant and/or a filler.

9. A pesticidal composition according to claim 1, wherein the weight of the compounds of formula I and compound II together comprise 1-90% by weight of the pesticidal composition.

10. A pesticidal composition according to claim 1, wherein the weight of the compounds of formula I and compound II together comprise from 5% to 80% by weight of the pesticidal composition.

11. A pesticidal composition according to claim 1, wherein the weight of the compounds of formula I and compound II together comprise from 5% to 50% by weight of the pesticidal composition.

12. The insecticidal composition according to claim 1 in the form of an emulsifiable concentrate, an aqueous suspension, an oil suspension, a seed-treatment dry powder, a seed-treatment suspension, a water dispersible granule, a wettable powder, a suspoemulsion, an aerosol, a coated granule, an extruded granule, an aqueous emulsion, a microcapsule suspension-suspension, a dry suspension, an ultra-low volume liquid, an electrostatic oil, a gel, a granule, a microparticle.

13. Use of the pesticidal composition of claim 1 for preventing or controlling pests and their larvae and eggs.

14. Use of the insecticidal composition according to claim 1 for the prevention or control of pests of the aphididae, psyllidae, leafhopper, aleyrodidae and lecanidae families.

15. Use of the insecticidal composition of claim 1 for preventing or controlling myzus persicae, cotton aphid, peach aphid, tea leafhopper, black tail leafhopper, whitefly, pear psyllid, diaphorina citri, scale insect pest and larvae and eggs thereof.

16. A method for preventing or controlling pests and their larvae and eggs, characterized in that the pesticidal composition according to claim 1 is applied to a target useful plant, a target pest or its environment, propagation material of a target useful plant.

17. A method for preventing or controlling pests and their larvae and eggs, characterized in that the pesticidal composition of claim 1 is applied to seeds, to the target useful plants or to the soil in which the plants are growing or to the soil suitable for plant growth.

18. A method for preventing or controlling pests and their larvae and eggs, characterized in that the pesticidal composition of claim 1 is applied to the soil before, after or before or after germination of the seed and/or directly to the soil in contact with the plant roots or to the soil suitable for plant growth.

19. A method of protecting seeds, characterized in that the seeds are contacted with a pesticidally effective amount of the pesticidal composition of claim 1 before sowing and/or after germination.