CN117427150A - Antibacterial repair composition and application thereof, antibacterial repair sanitary towel and preparation method thereof - Google Patents

Abstract

The application discloses an antibacterial repair composition and application thereof, and an antibacterial repair sanitary towel and a preparation method thereof; the antimicrobial repair composition comprises: collagen peptide: 0.8-3 parts; centella asiatica extract: 3-6 parts; yeast/rice fermentation product filtrate: 0.5-2 parts; fructus Gleditsiae Abnormalis extract: 0.5-2 parts; olive leaf extract: 1.5-4 parts. The collagen peptide, the centella asiatica extract, the saccharomycete/rice fermentation product filtrate and the olive leaf extract are selected as the antibacterial repairing composition, so that the antibacterial repairing composition has an excellent antibacterial effect, can comprehensively resist inflammation caused by skin problems and helps skin to be rapidly repaired.

Description

Antibacterial repair composition and use thereof, antibacterial repair sanitary napkin and preparation method thereof

Technical field

The present application relates to the technical field of sanitary products, specifically to an antibacterial repair composition and its use, antibacterial repair sanitary napkins and their preparation methods.

Background technique

As sanitary products used by women during menstruation, sanitary napkins are mainly made of cotton, non-woven fabrics, pulp or polymers and polymer composite paper formed by composites of the above materials. The function of sanitary napkins is to absorb the menstrual blood that comes from the vagina during menstruation.

With the progress and development of society, sanitary napkins, as female hygiene products, no longer only consider their basic uses, but other related properties have also attracted increasing attention from consumers. Due to endocrine effects during women's menstrual period, the menstrual blood produced by women during menstruation is accompanied by odor, and bacteria can easily breed on sanitary napkins, which can easily lead to infections of the reproductive system, urinary system, and other diseases.

In the existing technology, in order to achieve the sterilization function of sanitary napkins, some manufacturers will add sterilizing agents, such as nano-scale silver particles, into sanitary napkins. Some studies have shown that although silver ions have a certain sterilizing effect, long-term excessive use may pose a potential threat to the human body. Among them, long-term exposure to high concentrations of silver ions can cause damage to the skin, respiratory system, digestive system, etc.

Contents of the invention

The purpose of this application is to provide an antibacterial repair composition and its use, an antibacterial repair sanitary napkin and its preparation method.

In order to solve the above problems, this application proposes the following technical solutions:

In a first aspect, this application provides an antibacterial repair composition. In parts by weight, the antibacterial repair composition includes:

Collagen peptide: 0.8-3 parts;

Centella asiatica extract: 3-6 parts;

Yeast/rice fermentation product filtrate: 0.5-2 parts;

Honey locust extract: 0.5-2 parts;

Olive leaf extract: 1.5-4 parts.

As an embodiment, in parts by weight, the antibacterial repair composition includes:

Collagen peptide: 1.5-2.5 parts;

Centella asiatica extract: 4-6 parts;

Yeast/rice fermentation product filtrate: 1-2 parts;

Honey locust extract: 1-2 parts;

Olive leaf extract: 1.5-3.5 parts.

As a preferred embodiment, the weight ratio of the yeast/rice fermentation product filtrate and the honey locust extract is 1:1.

As an embodiment, the antibacterial repair composition further includes:

Propylene glycol: 15-20 parts; and/or

Water: 20-30 parts.

In a second aspect, the present application provides a use of the antibacterial repair composition as described in the first aspect in preparing sanitary products.

Among them, the above-mentioned sanitary products include but are not limited to wet wipes and sanitary napkins.

In a third aspect, this application provides an antibacterial repair sanitary napkin, which includes:

The main body of the sanitary napkin and the wings attached to both sides of the main body of the sanitary napkin;

The main body of the sanitary napkin is composed of a cotton soft layer, an antibacterial layer, a water-absorbent layer, a bottom layer, a release paper and a wrapping film;

Wherein, the antibacterial layer contains the antibacterial repair composition described in the first aspect.

As an embodiment, the water-absorbent layer adopts mesh non-woven fabric.

As an embodiment, the antibacterial layer uses spunlaced non-woven fabric.

As an embodiment, the preparation method of the antibacterial layer includes:

In proportion, stir and heat collagen peptides, centella asiatica extract, yeast/rice fermentation product filtrate, honey locust extract, olive leaf extract, water and/or propylene glycol to 40-50°C, and mix evenly to obtain antibacterial repair. combination;

Soak the spunlaced non-woven fabric in the antibacterial repair composition at 25-30°C for 10-15 minutes and dry it.

In the fourth aspect, the present application provides a method for preparing an antibacterial repair sanitary napkin as described in the third aspect. The method for preparing the sanitary napkin includes:

After cutting according to the size, the cotton soft layer, antibacterial layer, water-absorbent layer, bottom layer, release paper and wrapping film are bonded together in order to make the main body of the sanitary napkin;

Paste the wings on both sides of the main body of the sanitary napkin to obtain a sanitary napkin.

Compared with the prior art, this application has at least the following beneficial effects:

This application uses collagen peptides, centella asiatica extract, yeast/rice fermentation product filtrate and olive leaf extract as the antibacterial repair composition, which not only has excellent antibacterial effects, but also comprehensively resists inflammation caused by skin problems. And help the skin repair quickly. The above antibacterial repair composition is applied to sanitary products and has excellent antibacterial and repair effects.

Additional aspects and advantages of the invention will be set forth in part in the description which follows, and will be obvious from the description, or may be learned by practice of the invention.

Detailed ways

In order to more fully understand the technical content of the present application, the present application will be further introduced and explained below in conjunction with specific embodiments; obviously, the described embodiments are only some of the embodiments of the present application, not all of the embodiments; based on the present application All other embodiments obtained by those skilled in the art without creative efforts shall fall within the scope of protection of this application.

For those skilled in the art, the features, beneficial effects and advantages of the present application will become apparent by reading the disclosure of this specification.

The term "mass content" herein can be expressed by the symbol "parts".

In the following scheme, the corresponding raw materials can be purchased from the market or prepared according to common knowledge known in the art.

In the examples of this application, collagen peptides were purchased from Guangdong Baiwei Biotechnology Co., Ltd., Centella asiatica extract was purchased from Shanyang Lianfeng Biotechnology Co., Ltd., and yeast/rice fermentation product filtrate was purchased from Guangzhou Zhaoyi Biotechnology Co., Ltd. company, the honey locust extract was purchased from Guangzhou Baoyi Biotechnology Co., Ltd., and the olive leaf extract was purchased from Guangzhou Shengkesi Chemical Co., Ltd.

The antibacterial repair composition of the present application is described in detail below.

antibacterial repair composition

The antibacterial repair composition of the present application includes: collagen peptides, centella asiatica extract, yeast/rice fermentation product filtrate, honey locust extract and olive leaf extract.

The Centella asiatica extract used in this application has antibacterial and anti-inflammatory effects. At the same time, Centella asiatica extract tightens the connection between the epidermis and the dermis, making the connection between the epidermis and the dermis tighter. It can help the formation of collagen in the dermis, regenerate fibrin and reconnect, thus Achieve skin repair effect.

However, the skin utilization rate of Centella asiatica extract is relatively low, and its effect is difficult to exert, especially on damaged skin. In the existing technology, some penetration enhancers are usually used to help the skin use it, such as menthol and azone, but The above-mentioned penetration enhancers are all irritating and can easily cause irritation to the skin during use.

The collagen peptides used in this application can be quickly absorbed to repair the body's skin cells, repair the skin barrier, restore skin elasticity and restore skin luster. At the same time, it can also reduce inflammatory reactions and reduce the level of inflammatory mediators in the body. .

The yeast/rice fermentation product filtrate used in this application can activate body cells and prevent rough skin; it has a small molecular weight and super permeability, can quickly penetrate the skin, promote the activation and renewal of epidermal cells, and at the same time promote the production of collagen. and the renewal of elastic fibers, thereby increasing skin elasticity.

The honey locust extract used in this application has good antibacterial effects on Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Enterobacter cloacae, Enterobacter salmonellae and Candida albicans.

The olive leaf extract used in this application not only has excellent antibacterial effects, but can also promote the production of collagen by fibroblasts, thereby increasing skin elasticity.

This application uses collagen peptides, centella asiatica extract, yeast/rice fermentation product filtrate and olive leaf extract as the antibacterial repair composition, which not only has excellent antibacterial effects, but also comprehensively resists inflammation caused by skin problems. And help the skin repair quickly. The principle may be:

On the one hand, both collagen peptides and yeast/rice fermentation product filtrate have excellent penetration, which can quickly repair the body's skin cells, rebuild the skin barrier, promote the skin's absorption of Centella asiatica extract, thereby improving the efficiency of Centella asiatica extract. The skin utilization rate; on the other hand, Centella asiatica extract, which has significantly improved skin utilization rate, can not only participate in the bactericidal effect of honey locust extract and olive leaf extract, improve the overall bactericidal performance of the antibacterial repair composition, but also It works together with olive leaf extract, collagen peptides and yeast/rice fermentation product filtrate to further resist skin inflammation and promote collagen production and elastic fiber renewal, thereby increasing skin elasticity and repairing the skin.

The antibacterial repair composition provided by this application has the dual functions of antibacterial and skin repair.

The antibacterial repair composition provided by this application uses collagen peptides, yeast/rice fermentation product filtrate and various plant extracts, and the use process is gentle and non-irritating.

In this application, the contents of the above components in terms of parts by weight are: collagen peptide: 0.8-3 parts; Centella asiatica extract: 3-6 parts; yeast/rice fermentation product filtrate: 0.5-2 parts ;Glead extract: 0.5-2 parts; Olive leaf extract: 1.5-4 parts.

As the preferred technical solution of this application, the contents of the above components are respectively: collagen peptide: 1.5-2.5 parts; Centella asiatica extract: 4-6 parts; yeast/rice fermentation product filtrate: 1-2 parts; Glycyrrhiza lucidum Extract: 1-2 parts; Olive leaf extract: 1.5-3.5 parts.

For example, in this application:

The content of collagen peptides includes but is not limited to: 0.8 parts, 0.9 parts, 1.0 parts, 1.1 parts, 1.2 parts, 1.3 parts, 1.4 parts, 1.5 parts, 1.6 parts, 1.7 parts, 1.8 parts, 1.9 parts, 2.0 parts, 2.1 parts parts, 2.2 parts, 2.3 parts, 2.4 parts, 2.5 parts, 2.6 parts, 2.7 parts, 2.8 parts, 2.9 parts, 3.0 parts.

The content of Centella asiatica extract includes but is not limited to: 3 parts, 3.5 parts, 3.8 parts, 3.9 parts, 4 parts, 4.7 parts, 5 parts, 5.2 parts, 5.4 parts, 5.5 parts, 5.7 parts, 5.9 parts, 6 parts .

The content of yeast/rice fermentation product filtrate includes but is not limited to: 0.5 parts, 0.6 parts, 0.7 parts, 0.8 parts, 0.9 parts, 1.0 parts, 1.1 parts, 1.2 parts, 1.3 parts, 1.4 parts, 1.5 parts, 1.6 parts, 1.7 parts, 1.8 parts, 1.9 parts, 2.0 parts.

The content of soap locust extract includes but is not limited to: 0.5 parts, 0.6 parts, 0.7 parts, 0.8 parts, 0.9 parts, 1.0 parts, 1.1 parts, 1.2 parts, 1.3 parts, 1.4 parts, 1.5 parts, 1.6 parts, 1.7 parts, 1.8 parts parts, 1.9 parts, 2.0 parts.

The content of olive leaf extract includes but is not limited to: 1.5 parts, 1.6 parts, 1.7 parts, 1.8 parts, 1.9 parts, 2.0 parts, 2.1 parts, 2.2 parts, 2.3 parts, 2.4 parts, 2.5 parts, 2.6 parts, 2.7 parts, 2.8 parts, 2.9 parts, 3.0 parts, 3 parts, 3.5 parts, 3.8 parts, 3.9 parts, 4 parts.

As a more preferred technical solution of the present application, in the antibacterial repair composition, the weight ratio of the yeast/rice fermentation product filtrate and the honey locust extract is 1:1. This application has confirmed through relevant experiments that within this range, the antibacterial repair composition of this application has better antibacterial and repair effects.

Other components

In addition to the above components, the antibacterial repair composition of the present application can reasonably use other additives, such as solvents, within the scope that does not significantly damage the effect of the present application.

Wherein, the solvent may be selected from propylene glycol and/or water.

In this application, the dosage of propylene glycol is usually 15-20 parts, and the dosage of water is usually 20-30 parts.

The above-mentioned water is preferably purified water.

For example, the amount of water can be: 20 parts, 21 parts, 22 parts, 23 parts, 24 parts, 25 parts, 26 parts, 27 parts, 28 parts, 29 parts, 30 parts.

The dosage of propylene glycol can be: 15 parts, 16 parts, 17 parts, 18 parts, 19 parts, 20 parts, 21 parts, 22 parts, 23 parts, 24 parts, 25 parts.

The antibacterial repair composition of the present application is preferably in a liquid dosage form, that is, an antibacterial repair liquid.

Preparation

The antibacterial repair composition of the present application can be prepared using methods known in the art.

For example, the preparation method of the above-mentioned antibacterial repair composition includes:

In proportion, stir and heat collagen peptides, centella asiatica extract, yeast/rice fermentation product filtrate, honey locust extract, olive leaf extract, water and/or propylene glycol to 40-50°C, and mix evenly to obtain antibacterial repair. combination.

The antibacterial repair composition provided by this application can be used to prepare sanitary products. For example: it can be made into wet wipes or sanitary napkins.

The wet wipes and antibacterial repair sanitary napkins of this application will be introduced below.

wet wipes

The wet wipes of the present application include spunlace non-woven fabric and the above-mentioned antibacterial repair composition (antibacterial repair liquid). Specifically, the spunlace nonwoven fabric is soaked in the antibacterial repair composition at 25-30°C for 10-15 minutes to obtain the result.

Usually, the content of antibacterial repair solution in wet wipes is 75-85%, preferably 80-83%.

Therefore, the wet wipes of the present application not only have excellent antibacterial effects, but can also comprehensively resist inflammation caused by skin problems and help the skin repair quickly.

sanitary napkin

The sanitary napkin of the present application includes a main body of the sanitary napkin and wings attached to both sides of the main body of the sanitary napkin; wherein the main body of the sanitary napkin is composed of a soft cotton layer, an antibacterial layer, a water-absorbent layer, a bottom layer, a release paper and a wrapping film in order .

Among them, the antibacterial layer contains the above-mentioned antibacterial repair composition (antibacterial repair liquid).

The preparation method of the above-mentioned sanitary napkin includes:

After cutting according to the size, the cotton soft layer, antibacterial layer, water-absorbent layer, bottom layer, release paper and wrapping film are bonded together in order to make the main body of the sanitary napkin, and then the wings are pasted on both sides of the main body of the sanitary napkin to get sanitary napkin.

Among them, the water-absorbent layer is preferably mesh non-woven fabric, and the antibacterial layer is preferably spunlace non-woven fabric.

In the embodiment of the present application, the preparation method of the antibacterial layer is:

In proportion, stir and heat collagen peptides, centella asiatica extract, yeast/rice fermentation product filtrate, honey locust extract, olive leaf extract, water and/or propylene glycol to 40-50°C, and mix evenly to obtain antibacterial repair. combination;

Soak the spunlaced non-woven fabric in the antibacterial repair composition at 25-30°C for 10-15 minutes and dry it.

Therefore, the sanitary napkin of the present application not only has the care function of ordinary sanitary napkins, but also has excellent antibacterial effect. At the same time, it can comprehensively resist inflammation caused by skin problems and help the skin repair quickly.

The present application will be further described below in conjunction with examples. It should be understood that these examples are only used to illustrate the present application and are not intended to limit the scope of the present application.

In the following examples, the materials, reagents and instruments used can be purchased from commercial sources unless otherwise specified.

Example 1-Example 6

In this application, an antibacterial repair solution with the following examples was prepared, and the specific composition is shown in Table 1.

Table 1: Components and dosage (parts) of Examples 1-6

Components Example 1 Example 2 Example 3 Example 4 Example 5 Example 6 collagen peptides 0.8 1.5 2.5 3 2 3 Centella asiatica extract 6 5 4 3 4 4.5 Yeast/rice fermentation product filtrate 1 2 1.5 0.5 1 1.5 Honey Locust Extract 1 0.5 1.5 2 0.5 1 olive leaf extract 2.7 2.5 2 3 4 1.5 propylene glycol 18 18 18 18 18 18 water twenty two twenty two twenty two twenty two twenty two twenty two

Comparative Example 1-Comparative Example 5

In this application, the antibacterial repair solution of the following comparative examples was also prepared, and the specific composition is shown in Table 2.

Table 2: Components and dosage (parts) of Comparative Examples 1-5

Components Comparative example 1 Comparative example 2 Comparative example 3 Comparative example 4 Comparative example 5 collagen peptides - 3 3.5 2.5 2.5 Centella asiatica extract 5.5 5 - 4.5 5 Yeast/rice fermentation product filtrate 2.5 - 2.5 1.5 1.5 Honey Locust Extract 1.5 1.5 2.5 - 2.5 olive leaf extract 2 2 3 3 - propylene glycol 18 18 18 18 18 water twenty two twenty two twenty two twenty two twenty two

The preparation method of the antibacterial repair solution of Examples 1-6 and Comparative Examples 1-5 includes the following steps:

According to the proportion, stir and heat collagen peptides, centella asiatica extract, yeast/rice fermentation product filtrate, honey locust extract, olive leaf extract, water and/or propylene glycol to 45°C, and mix evenly to obtain an antibacterial repair solution.

Effect verification

The effect of the antibacterial repair solution prepared in the above Examples 1-6 and Comparative Examples 1-5 is verified, specifically including:

Antibacterial performance test:

Soak the spunlaced non-woven fabric in the corresponding antibacterial repair solution at 25°C for 15 minutes to obtain antibacterial repair wipes.

Refer to FZ/T73023-2006 "Antibacterial Knitted Products" to measure the antibacterial performance of the above wet wipes. Test strains: Escherichia coli, Staphylococcus aureus, and Candida albicans. Among them, the antibacterial performance is expressed by the bacteriostatic rate. The test results are shown in Table 3 below.

Table 3: Antibacterial rate (%) of Examples 1-6 and Comparative Examples 1-5

Antibacterial rate Example 1 Example 2 Example 3 Example 4 Example 5 Example 6 Comparative example 1 Comparative example 2 Comparative example 3 Comparative example 4 Comparative example 5 E. coli 99.5 98.5 99.5 98.2 98.3 98.6 86.6 88.2 82.5 81.5 80.9 Staphylococcus aureus 98.6 98.2 99.8 97.4 97.3 97.8 86.7 88.5 82.7 81.3 80.7 Candida albicans 98.2 96.8 98.7 96.5 96.6 96.9 85.8 87.6 81.8 80.4 80.0

According to the test results in Table 3, Examples 1-5 of the present application selected collagen peptides, centella asiatica extract, yeast/rice fermentation product filtrate and olive leaf extract as antibacterial repair compositions, which have excellent antibacterial effects. .

Among them, in Comparative Examples 1-2, due to the lack of collagen peptides or yeast/rice fermentation product filtrate, the skin utilization rate of Centella asiatica extract was significantly reduced, which further resulted in the obvious weakening of the antibacterial effect of Comparative Examples 1-2.

In Comparative Example 3-5, the antibacterial effect of Comparative Example 3-5 was significantly weakened due to the lack of centella asiatica extract, honey locust extract or olive leaf extract. It shows that centella asiatica extract, honey locust extract and olive leaf extract have a synergistic effect on the antibacterial effect.

Centella asiatica extract skin penetration test

The Centella asiatica extract skin penetration test is based on the existing Franz diffusion cell method;

The specific experimental steps are:

The in vitro Franz diffusion cell test was conducted using the back skin of healthy male Wistar rats as a permeability barrier;

Fix the intact and undamaged skin between the receiving pool and the supply pool (where the inner layer of the skin faces the receiving pool) to ensure that there are no air bubbles between the skin and the receiving fluid;

Diffusion cell parameters: effective diffusion area is about 3.15cm ² , receiving cell volume is about 8.8mL, magnetic stirring speed is 600rpm, and the temperature of the receiving liquid is 36.0±0.1℃;

Fill the receiving pool with the release medium 1% SDS-10% ethanol-physiological saline, eliminate air bubbles, start stirring, and keep the temperature constant to (36.0±0.1)°C, and evenly apply about 1g of the sample to the skin surface (n=8);

Aspirate 0.5 mL of the receiving solution at 1, 2, 4, 6, 8, 10, and 12 hours. Immediately after sampling, add the same volume of release medium at the same temperature. Use HPLC to measure the concentration of Centella asiatica extract in the receiving solution filtered through a 0.22 μm filter membrane. Calculate the cumulative drug penetration at different times.

Calculate the cumulative transdermal amount per unit area of Centella asiatica extract according to the following formula:

;

In the above formula: Q: Cumulative transdermal amount; S: Effective diffusion area; V: Volume of normal saline in the receiving pool; C _i : Drug concentration in the receiving solution from the first to the last sampling; C _n : Received during this sampling Concentration of drug in liquid; m ₀ : theoretical weighing volume of sample; m: actual weighing volume of sample.

The test results are shown in Table 4.

Table 4: Cumulative skin penetration of centella asiatica extract (12h)

Example 3 Comparative example 1 Comparative example 2 Cumulative permeability of Centella asiatica extract 1424μg/ ^cm2 525μg/ ^cm2 568μg/ ^cm2

According to the test results in Table 4, in the absence of either collagen peptides or yeast/rice fermentation product filtrate, the skin utilization rate of Centella asiatica extract significantly decreased, indicating that in the scheme of the present application, collagen peptides Together with the yeast/rice fermentation product filtrate, it can quickly repair the body's skin cells, rebuild the skin barrier, and promote the skin's absorption of Centella asiatica extract, thus improving the skin utilization rate of Centella asiatica extract, thereby exerting the effect of Centella asiatica extract. Antibacterial and restorative effects of grass extract.

Repair effect test

Test subjects: 110 healthy women aged 25-45, divided into 11 groups, with 10 people in each group.

Test area: face (the left face is a blank control, and the right face uses a comparative sample or example sample).

Usage: Apply once a day in the morning and evening (same dosage) and continue to use for 28 days.

Testing instrument: CK skin tester (Germany)

Test parameters: skin stratum corneum moisture, transepidermal water loss value

After 28 days, use a CK skin tester (Germany) to measure the change rate of the moisture content of the skin's stratum corneum and the change rate of transepidermal water loss. The higher the change rate of the moisture content of the skin's stratum corneum, the better the skin's moisture content; transepidermal water loss The lower the rate change rate, the better the skin barrier. The test results are shown in Table 5.

table 5:

sample set Moisture content change rate (%) Transcutaneous water loss change rate (%) Example 1 5.46 1.53 Example 2 5.55 1.45 Example 3 5.68 1.34 Example 4 5.52 1.43 Example 5 5.25 1.64 Example 6 5.26 1.66 Comparative example 1 3.02 2.89 Comparative example 2 3.15 2.75 Comparative example 3 3.55 2.08 Comparative example 4 4.46 1.87 Comparative example 5 4.35 1.91

According to the test results in Table 5, Examples 1-6 of the present application can effectively help skin by selecting collagen peptides, centella asiatica extract, yeast/rice fermentation product filtrate and olive leaf extract as antibacterial repair compositions. Quick fix.

Among them, in Comparative Examples 1-2, in the absence of collagen peptides or yeast/rice fermentation product filtrate, the skin utilization rate of Centella asiatica extract was significantly reduced. At the same time, due to the collagen peptide and yeast/rice fermentation product filtrate It itself can repair the body's skin cells and rebuild the skin barrier, thus causing the repair effect of Comparative Examples 1-2 to be significantly weakened.

In Comparative Example 3, due to the lack of Centella asiatica extract, the repair effect was significantly weakened, indicating that Centella asiatica extract, collagen peptides, and yeast/rice fermentation product filtrate have a synergistic effect in repair.

The lack of honey locust extract or olive leaf extract in Comparative Examples 4-5 also resulted in a weakening of the repair effect of Comparative Examples 4-5. It shows that the solutions of honey locust extract and olive leaf extract in this application also have an impact on the repair effect, but the overall impact is relatively small.

Security testing

1. Number of testers: 36 people in total, 18 males and 18 females; minimum age: 25 years old, maximum age: 40 years old; the average age meets the inclusion criteria.

2. Test method: Examples 1-6 are used for patch testing. Select a qualified patch tester and use the closed patch test method. Place approximately 0.020-0.025mL of the test substance into the patch tester. Apply external medical tape to the back of the subject. Remove the test substance after 24 hours. Observe skin reactions 0.5, 24, and 48 hours after removal of the patch, and record the results according to the skin reaction grading standards in the "Safety and Technical Specifications for Cosmetics" (2015 Edition). The evaluation standards are as follows in Table 6, and the test results are in Table 7.

Table 6: Grading and evaluation criteria for adverse skin reactions

Level of reaction Rating level skin reaction — 0 negative reaction ± 1 Suspicious reaction: only faint erythema + 2 Weak positive reaction (erythema reaction): erythema, infiltration, edema, and possibly papules ++ 3 Strong positive reaction (herpetic reaction): erythema, infiltration, edema, papules, herpes: reaction may extend beyond the tested area +++ 4 Extremely strong positive reaction (confluent herpetic reaction): marked erythema, severe infiltration, edema, confluent herpetic reaction: reaction beyond the tested area

Table 7: Security test results

Rating level Example 1 Example 2 Example 3 Example 4 Example 5 Example 6 0.5(h) 0 0 0 0 0 0 24(h) 0 0 0 0 0 0 48(h) 0 0 0 0 0 0

The results in Table 7 show that in the closed patch test on human skin of Examples 1-6, no positive reaction was found among 30 people. According to the "Safety Technical Specifications for Cosmetics" (2015 Edition), the test substance has no effect on this test. Batch subjects did not cause adverse skin reactions.

In summary, this application uses collagen peptides, centella asiatica extract, yeast/rice fermentation product filtrate and olive leaf extract as the antibacterial repair composition, which not only has excellent antibacterial effects, but also comprehensively resists Inflammation caused by skin problems and helps the skin repair quickly.

The technical solutions provided by the embodiments of the present application are introduced in detail above. Specific examples are used in this article to illustrate the principles and implementation methods of the embodiments of the present application. The description of the above embodiments is only applicable to help understand the embodiments of the present application. Principle; at the same time, for those of ordinary skill in the art, there will be changes in the specific implementation methods and application scope according to the embodiments of the present application. In summary, the content of this description should not be understood as a limitation of the present application.

Claims (10)

1. An antibacterial repair composition, characterized in that, in parts by weight, the antibacterial repair composition includes: Collagen peptide: 0.8-3 parts; Centella asiatica extract: 3-6 parts; Yeast/rice fermentation product filtrate: 0.5-2 parts; Honey locust extract: 0.5-2 parts; Olive leaf extract: 1.5-4 parts. 2. The antibacterial repair composition as claimed in claim 1, characterized in that, in parts by weight, the antibacterial repair composition includes: Collagen peptide: 1.5-2.5 parts; Centella asiatica extract: 4-6 parts; Yeast/rice fermentation product filtrate: 1-2 parts; Honey locust extract: 1-2 parts; Olive leaf extract: 1.5-3.5 parts. 3. The antibacterial repair composition according to claim 1 or 2, wherein the weight ratio of the yeast/rice fermentation product filtrate and the honey locust extract is 1:1. 4. The antibacterial repair composition according to claim 1 or 2, characterized in that the antibacterial repair composition further includes: Propylene glycol: 15-20 parts; and/or Water: 20-30 parts. 5. Use of the antibacterial repair composition according to any one of claims 1 to 4 in the preparation of sanitary products. 6. An antibacterial repair sanitary napkin, characterized in that the sanitary napkin includes: The main body of the sanitary napkin and the wings attached to both sides of the main body of the sanitary napkin; The main body of the sanitary napkin is composed of a cotton soft layer, an antibacterial layer, a water-absorbent layer, a bottom layer, a release paper and a wrapping film; Wherein, the antibacterial layer contains the antibacterial repair composition according to any one of claims 1-4. 7. The antibacterial repair sanitary napkin according to claim 6, wherein the water-absorbent layer is made of mesh non-woven fabric. 8. The antibacterial repair sanitary napkin according to claim 6, wherein the antibacterial layer is made of spunlaced non-woven fabric. 9. The antibacterial repair sanitary napkin according to claim 8, wherein the preparation method of the antibacterial layer includes: In proportion, stir and heat collagen peptides, centella asiatica extract, yeast/rice fermentation product filtrate, honey locust extract, olive leaf extract, water and/or propylene glycol to 40-50°C, and mix evenly to obtain antibacterial repair. combination; Soak the spunlaced non-woven fabric in the antibacterial repair composition at 25-30°C for 10-15 minutes and dry it. 10. The preparation method of the antibacterial repair sanitary napkin according to any one of claims 6 to 9, characterized in that the preparation method of the sanitary napkin includes: After cutting according to the size, the cotton soft layer, antibacterial layer, water-absorbent layer, bottom layer, release paper and wrapping film are bonded together in order to make the main body of the sanitary napkin; Paste the wings on both sides of the main body of the sanitary napkin to obtain a sanitary napkin.