CN117170445A - Online real-time supervision management and control system of chemical industry pharmacy production line environment - Google Patents
Online real-time supervision management and control system of chemical industry pharmacy production line environment Download PDFInfo
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- CN117170445A CN117170445A CN202311356236.4A CN202311356236A CN117170445A CN 117170445 A CN117170445 A CN 117170445A CN 202311356236 A CN202311356236 A CN 202311356236A CN 117170445 A CN117170445 A CN 117170445A
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- 238000004519 manufacturing process Methods 0.000 title claims abstract description 63
- 239000000126 substance Substances 0.000 title claims abstract description 47
- 238000012544 monitoring process Methods 0.000 claims abstract description 136
- 238000012545 processing Methods 0.000 claims abstract description 26
- 230000007613 environmental effect Effects 0.000 claims abstract description 18
- 238000012423 maintenance Methods 0.000 claims abstract description 13
- 230000005856 abnormality Effects 0.000 claims abstract description 7
- 238000012806 monitoring device Methods 0.000 claims description 13
- 239000002245 particle Substances 0.000 claims description 9
- 230000001580 bacterial effect Effects 0.000 claims description 6
- 238000005286 illumination Methods 0.000 claims description 6
- 241000894006 Bacteria Species 0.000 claims description 4
- 238000010276 construction Methods 0.000 claims description 4
- 238000001514 detection method Methods 0.000 claims description 4
- 201000010099 disease Diseases 0.000 claims description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 4
- 238000004659 sterilization and disinfection Methods 0.000 claims description 4
- 238000004887 air purification Methods 0.000 claims description 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 3
- 239000000428 dust Substances 0.000 claims description 3
- 239000007789 gas Substances 0.000 claims description 3
- 244000005700 microbiome Species 0.000 claims description 3
- 239000001301 oxygen Substances 0.000 claims description 3
- 229910052760 oxygen Inorganic materials 0.000 claims description 3
- 230000000737 periodic effect Effects 0.000 claims description 3
- 229920000642 polymer Polymers 0.000 claims description 3
- 230000003749 cleanliness Effects 0.000 claims description 2
- 230000007306 turnover Effects 0.000 claims description 2
- 239000003814 drug Substances 0.000 abstract description 15
- 230000005540 biological transmission Effects 0.000 abstract description 2
- 238000000034 method Methods 0.000 description 15
- 230000008569 process Effects 0.000 description 11
- 238000010586 diagram Methods 0.000 description 8
- 230000002159 abnormal effect Effects 0.000 description 3
- 230000009471 action Effects 0.000 description 3
- 239000002689 soil Substances 0.000 description 3
- 238000011161 development Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 208000035473 Communicable disease Diseases 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000010924 continuous production Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000003862 health status Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P90/00—Enabling technologies with a potential contribution to greenhouse gas [GHG] emissions mitigation
- Y02P90/02—Total factory control, e.g. smart factories, flexible manufacturing systems [FMS] or integrated manufacturing systems [IMS]
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Abstract
The invention relates to the technical field of pharmaceutical environment control and discloses an online real-time monitoring and controlling system for the environment of a chemical pharmaceutical production line, which comprises a system control center, wherein the output end of the system control center is connected with a data processing unit in a signal manner, the output end of the data processing unit is connected with a monitoring and controlling module in a signal manner, and the output end of the monitoring and controlling module is connected with an environment protection unit, an equipment monitoring unit, an environment monitoring unit, an abnormality alarm module and an environment maintenance module in a signal manner. This online real-time supervision management and control system of chemical industry pharmacy production line environment carries out detailed monitoring to the environment on the chemical industry pharmacy workshop production line to in data transmission to the data processing unit that the monitoring produced, judge after the processing of data processing unit to data, environment maintenance module can be timely carry out timely processing to the region or the equipment that have the problem after reporting to the police, thereby reduce the influence of chemical industry pharmacy workshop's environmental problem to medicine quality.
Description
Technical Field
The invention relates to the technical field of pharmaceutical environment management and control, in particular to a chemical pharmaceutical production line environment online real-time monitoring management and control system.
Background
Along with development and progress of science and technology, the chemical pharmacy also obtains quick development, the environmental requirement to chemical pharmacy production line at chemical pharmacy production's in-process is also very strict, in order to ensure that chemical pharmacy production line environment can accord with chemical pharmacy production's requirement, in the production process of medicine at the workshop, the quality of medicine and the environment of workshop are closely related, if the environment of workshop does not accord with the requirement, on the one hand can influence the production quality of current medicine, and then can't guarantee the income of medicine, on the other hand influences the continuous production of medicine, brings adverse effect for workshop manufacturer. Therefore, the environment of the chemical pharmaceutical production line needs to be monitored in the chemical pharmaceutical process.
The environment monitoring of the existing chemical pharmaceutical production line is mainly carried out on the environment on a production line of a pharmaceutical workshop in a passive and regular mode, the environment on the chemical pharmaceutical production line cannot be monitored and controlled, environmental problems in the process of chemical pharmaceutical are caused, timely discovery and treatment cannot be carried out, and accordingly the production quality of chemical pharmaceutical medicines is affected.
Disclosure of Invention
The invention aims to provide an online real-time monitoring and controlling system for the environment of a chemical pharmaceutical production line, which aims to solve the problems in the background technology.
In order to achieve the above purpose, the present invention provides the following technical solutions: the utility model provides an online real-time supervision control system of chemical industry pharmacy production line environment, includes system control center, system control center output signal is connected with data processing unit, data processing unit output signal is connected with the monitoring management and control module, monitoring management and control module output signal is connected with environmental protection unit, equipment monitoring unit, environmental monitoring unit, unusual alarm module and environmental maintenance module.
The environment monitoring unit output end signal is connected with a monitoring target, monitoring equipment and an instrument, and the monitoring target comprises: air quality monitoring module, noise monitoring module and illuminance monitoring module.
The monitoring device and instrument comprises; air monitoring equipment, noise monitoring equipment, humiture monitoring module and illumination monitoring module.
Preferably, the air monitoring module includes: oxygen content, concentration of harmful gases, dust and particle concentration.
Preferably, the air monitoring device comprises an air monitor; the noise monitoring device comprises a decibel meter, and the illuminance monitoring device comprises an illuminance meter; the temperature and humidity monitoring equipment comprises a temperature and humidity sensor.
Preferably, when the air monitoring equipment, the noise monitoring equipment, the temperature and humidity monitoring module and the illumination monitoring module are used, corresponding threshold values are formulated according to the environmental requirements of the chemical pharmaceutical production line.
Preferably, the threshold value includes: the air purification level in the workshop reaches above ISO5 level, namely the concentration of polymer particles is less than or equal to 1000 particles/m 3 The total number of microorganisms is less than or equal to 1CFU/4 hours; the maximum allowable noise is 80 db; the minimum temperature is 20 ℃, and the maximum temperature is 24 ℃; the minimum humidity is 45% and the maximum humidity is 60%.
Preferably, the signal connection of the output end of the environment protection module is provided with a personnel protection module and an external environment protection module, the personnel protection module comprises an in-out disinfection module and a disease inquiry module, and the signal connection of the output end of the external environment protection module is provided with a site selection module.
Preferably, the factors to be considered by the site selection module include: geographic location, natural environment, public facilities and infrastructure, land and construction and legal regulations and policies.
Preferably, the output end of the equipment monitoring unit is in signal connection with an equipment sanitation monitoring module, equipment noise monitoring and equipment bacteria monitoring; the equipment sanitary monitoring means that only equipment is maintained and cleaned in a designated period, so that the cleanness of pharmaceutical production equipment is ensured; the equipment noise monitoring means that the noise of the pharmaceutical equipment is monitored in the using process; the equipment bacterial monitoring refers to the periodic detection of bacterial content of pharmaceutical equipment.
Preferably, the data processing unit comprises a data receiving module, the output end of the data receiving module is in signal connection with a data sorting module, the output end of the data sorting module is in signal connection with a data judging module, and the output end of the data judging module is in signal connection with a data output module.
Preferably, the data judging module is used for comparing and judging the data information and the threshold value data when the monitoring modules monitor and control the production line environment on line in real time, if the numerical value does not exceed the threshold value, the control is passed, and if the numerical value exceeds the threshold value, the abnormality alarming module and the environment maintenance module are started.
Compared with the prior art, the invention has the beneficial effects that:
1. this online real-time supervision management and control system of chemical industry pharmacy production line environment can be respectively control the monitoring target and the check out test set and the monitoring instrument of pharmacy workshop through setting up the environmental monitoring unit to carry out detailed monitoring to the environment on the chemical industry pharmacy workshop production line, and in the data transmission to the data processing unit that will monitor the production, judge after the processing of data processing unit to data, if monitor data surpass the threshold, carry out unusual warning, environmental maintenance module can be timely carry out timely processing to the region or the equipment that have the problem after reporting to the police, thereby reduce the influence of the environmental problem of chemical industry pharmacy production workshop to medicine quality, be worth using widely.
2. This online real-time supervision management and control system of chemical industry pharmacy production line environment is through setting up environmental protection unit, disinfects the business turn over of staff in chemical industry pharmacy workshop to detect chemical industry pharmacy production workshop staff's health status, avoid chemical industry pharmacy production workshop staff to have the phenomenon of infectious disease, thereby influence chemical industry pharmacy's medicine, in addition, through factors such as taking into account geographical position, natural environment, public facility and infrastructure, soil and building and legal regulation and policy when selecting the site in pharmacy workshop, thereby avoid the influence that external environment produced the medicine.
Drawings
FIG. 1 is a schematic diagram of a system according to the present invention;
FIG. 2 is a schematic diagram of an environmental monitoring unit according to the present invention;
FIG. 3 is a schematic diagram of a monitoring device and apparatus of the present invention;
FIG. 4 is a schematic diagram of an air quality monitoring module according to the present invention
FIG. 5 is a schematic diagram of an environmental protection unit according to the present invention;
FIG. 6 is a schematic diagram of a monitoring unit of the apparatus of the present invention;
FIG. 7 is a schematic diagram of a data processing unit according to the present invention;
fig. 8 is a schematic diagram of a data determination flow according to the present invention.
In the figure: 1. a system control center; 2. a data processing unit; 21. a data receiving module; 22. a data arrangement module; 23. a data judging module; 24. a data output module; 3. monitoring and controlling the module; 4. an abnormality alarm module; 5. an environmental maintenance module; 6. an environmental protection unit; 61. a personnel protection module; 611. entering and exiting the disinfection module; 612. a disease query module; 62. an external environment protection module; 621. a site selection module; 7. an equipment monitoring unit; 8. an environment monitoring unit; 81. monitoring a target; 811. an air quality monitoring module; 812. a noise monitoring module; 813. an illuminance monitoring module; 82. monitoring equipment and instruments; 821. monitoring equipment sanitation; 822. monitoring equipment noise; 823. and (5) monitoring bacteria of the equipment.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
The invention provides the following technical scheme:
example 1
Referring to fig. 1-3, an online real-time monitoring and controlling system for an environment of a chemical pharmaceutical production line comprises a system control center 1, wherein an output end signal of the system control center 1 is connected with a data processing unit 2, an output end signal of the data processing unit 2 is connected with a monitoring and controlling module 3, an output end signal of the monitoring and controlling module 3 is connected with an environment protection unit 6, an equipment monitoring unit 7, an environment monitoring unit 8, an abnormality alarming module 4 and an environment maintenance module 5, and the monitoring target 81, the detection equipment and the monitoring instrument of the pharmaceutical production line can be respectively controlled by the environment monitoring unit 8, so that the environment on the pharmaceutical production line of the chemical pharmaceutical production line is monitored in detail, data generated by monitoring is transmitted to the data processing unit 2, after the data processing unit 2 processes the data, abnormal alarming is carried out if the monitored data exceeds a threshold value, the environment maintenance module 5 can timely process the area or the equipment with problems after alarming, and thus the influence of the environmental problem of the pharmaceutical production line on the quality of the pharmaceutical production line is reduced.
The environment monitoring unit 8 output end signal connection has monitor target 81 and monitoring equipment and instrument 82, and monitor target 81 includes: an air quality monitoring module 811, a noise monitoring module 812 and an illuminance monitoring module 813.
The monitoring device and instrument 82 includes; air monitoring equipment, noise monitoring equipment, humiture monitoring module and illumination monitoring module.
Specifically, the air monitoring module includes: the air quality monitoring module 811 monitors various aspects of oxygen content, harmful gas content, dust and particle concentration in the production plant.
Specifically, the air monitoring device includes an air monitor; the noise monitoring device comprises a decibel meter, and the illuminance monitoring device comprises an illuminance meter; the temperature and humidity monitoring equipment comprises a temperature and humidity sensor.
Specifically, when using air monitoring equipment, noise monitoring equipment, humiture monitoring module and illumination monitoring module, corresponding threshold is formulated according to the demand of chemical industry pharmacy production line environment.
Specifically, the threshold includes: the air purification level in the workshop reaches above ISO5 level, namely the concentration of polymer particles is less than or equal to 1000 particles/m 3 The total number of microorganisms is less than or equal to 1CFU/4 hours; the maximum allowable noise is 80 db; the minimum temperature is 20 ℃, and the maximum temperature is 24 ℃; the minimum humidity is 45% and the maximum humidity is 60%.
Example two
With reference to fig. 1 to 4, on the basis of the first embodiment, a personnel protection module 61 and an external environment protection module 62 are further connected to an output end signal of the environment protection module, the personnel protection module 61 includes an in-out disinfection module 611 and a disease query module 612, and a site selection module 621 is connected to an output end signal of the external environment protection module 62.
The data processing unit 2 comprises a data receiving module 21, wherein the output end of the data receiving module 21 is in signal connection with a data sorting module 22, the output end of the data sorting module 22 is in signal connection with a data judging module 23, and the output end of the data judging module 23 is in signal connection with a data output module 24.
Specifically, the site selection module 621 may consider factors including: geographic location, natural environment, public facilities and infrastructure, land and construction and legal regulations and policies.
Geographic location: the pharmaceutical production enterprises need to select a factory building with excellent geographic position, so that raw materials can be conveniently obtained, finished products can be transported, and daily operation can be conveniently carried out; in addition, the factory building position is convenient for staff to get on and off duty, so that the time for staff to commute and the inconvenience caused by inconvenient traffic are reduced.
Natural environment: the factory building of the medicine production enterprises should be built in places with relatively clean environment and no pollution. For example, it should be located far from the sites where pollution may occur, such as chemical plants, garbage disposal plants, etc. In addition, the climate conditions and the risks of natural disasters should be considered, and areas with lower risks should be selected as much as possible.
Public facilities and infrastructure: the factory building of the pharmaceutical manufacturing company should be built in a place where public facilities and infrastructure are complete, for example, close to public facilities for electric power, water supply, water discharge, communication, etc., so that these facilities can be conveniently used.
Land and construction: the factory building of medicine manufacturing enterprise needs sufficient soil and building, and the soil should be even, open, easily drainage and ventilation. The building should meet the requirements of the quality management standard of the medicine production, have sufficient space, stable and good structure and design, and adapt to the requirements of the medicine production.
Legal regulations and policies: the factory building of the medicine production enterprises should be built in a relatively stable and transparent area of laws and regulations and policies, so that uncertainty and risks encountered by the enterprises in the operation process can be reduced.
Specifically, the output end of the equipment monitoring unit 7 is in signal connection with an equipment sanitation monitoring 821 module, an equipment noise monitoring 822 and an equipment bacteria monitoring 823; the equipment sanitation monitoring 821 refers to maintenance and cleaning of only equipment at a designated period, so that the cleanliness of pharmaceutical production equipment is ensured; device noise monitoring 822 refers to monitoring noise of pharmaceutical devices during use; device bacterial monitoring 823 refers to the periodic detection of bacterial content of pharmaceutical devices.
Specifically, the data judging module 23 is configured to compare and judge the data information and the threshold value data when the monitoring modules monitor and control the production line environment online in real time, if the value does not exceed the threshold value, the control is passed, and if the value exceeds the threshold value, the abnormality alarming module 4 and the environment maintenance module 5 are started.
In the actual operation process, when the device is used, the system control center 1 can control the whole system, the environment monitoring unit 8 monitors the environment of the chemical pharmaceutical production workshop, and the equipment monitoring unit 7 monitors equipment of the production workshop; the environmental protection unit 6 monitors staff in the chemical industry pharmaceutical production workshop, and the monitoring data are transmitted to the data processing unit 2 in real time through the monitoring management and control module 3 for processing, and through inputting, arranging and judging the data, if the monitoring data exceeds a threshold value, the abnormal alarm module 4 is started to alarm, and the environment maintenance module 5 maintains and processes the abnormal point while alarming, so that the purpose of monitoring, managing and controlling the environment of the chemical industry pharmaceutical production line in real time is achieved.
It is noted that relational terms such as first and second, and the like are used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Moreover, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising one does not exclude the presence of other like elements in a process, method, article, or apparatus that comprises an element.
Claims (10)
1. Chemical industry pharmacy production line environment on-line real-time supervision management and control system, including system control center (1), its characterized in that: the system comprises a system control center (1), a data processing unit (2), a monitoring control module (3), an environment protection unit (6), an equipment monitoring unit (7), an environment monitoring unit (8), an abnormality alarm module (4) and an environment maintenance module (5), wherein the output end of the system control center (1) is connected with the data processing unit (2) through signals, and the output end of the data processing unit (2) is connected with the monitoring control module (3) through signals;
the environment monitoring unit (8) output end signal connection has monitoring target (81) and monitoring equipment and instrument (82), monitoring target (81) include: an air quality monitoring module (811), a noise monitoring module (812) and an illuminance monitoring module (813);
the monitoring device and instrument (82) includes; air monitoring equipment, noise monitoring equipment, humiture monitoring module and illumination monitoring module.
2. The chemical pharmaceutical production line environment online real-time monitoring and controlling system according to claim 1, wherein: the air monitoring module includes: oxygen content, concentration of harmful gases, dust and particle concentration.
3. The chemical pharmaceutical production line environment online real-time monitoring and controlling system according to claim 1, wherein: the air monitoring device includes an air monitor; the noise monitoring device comprises a decibel meter, and the illuminance monitoring device comprises an illuminance meter; the temperature and humidity monitoring equipment comprises a temperature and humidity sensor.
4. The chemical pharmaceutical production line environment online real-time monitoring and controlling system according to claim 1, wherein: when the air monitoring equipment, the noise monitoring equipment, the temperature and humidity monitoring module and the illumination monitoring module are used, corresponding threshold values are formulated according to the environmental requirements of the chemical pharmaceutical production line.
5. The chemical pharmaceutical production line environment online real-time monitoring and controlling system according to claim 1, wherein: the threshold includes: the air purification level in the workshop reaches above ISO5 level, namely the concentration of polymer particles is less than or equal to 1000 particles/m 3 The total number of microorganisms is less than or equal to 1CFU/4 hours; the maximum allowable noise is 80 db; the minimum temperature is 20 ℃, and the maximum temperature is 24 ℃; the minimum humidity is 45% and the maximum humidity is 60%.
6. The chemical pharmaceutical production line environment online real-time monitoring and controlling system according to claim 1, wherein: the environment protection module output end signal connection has personnel protection module (61) and external environment protection module (62), personnel protection module (61) are including business turn over disinfection module (611) and disease inquiry module (612), external environment protection module (62) output end signal connection has place selection module (621).
7. The online real-time monitoring and controlling system for the environment of the chemical pharmaceutical production line according to claim 6, wherein: factors that should be considered by the site selection module (621) include: geographic location, natural environment, public facilities and infrastructure, land and construction and legal regulations and policies.
8. The chemical pharmaceutical production line environment online real-time monitoring and controlling system according to claim 1, wherein: the output end of the equipment monitoring unit (7) is in signal connection with an equipment sanitation monitoring (821) module, an equipment noise monitoring (822) module and an equipment bacteria monitoring (823) module; the equipment hygiene monitoring (821) is used for ensuring the cleanliness of pharmaceutical production equipment as long as the equipment is maintained and cleaned in a designated period; device noise monitoring (822) refers to monitoring of noise of pharmaceutical devices during use; the equipment bacterial monitoring (823) refers to the periodic detection of bacterial content of pharmaceutical equipment.
9. The chemical pharmaceutical production line environment online real-time monitoring and controlling system according to claim 1, wherein: the data processing unit (2) comprises a data receiving module (21), wherein the output end of the data receiving module (21) is in signal connection with a data sorting module (22), the output end of the data sorting module (22) is in signal connection with a data judging module (23), and the output end of the data judging module (23) is in signal connection with a data output module (24).
10. The online real-time monitoring and controlling system for the environment of the chemical pharmaceutical production line according to claim 9, wherein: the data judging module (23) is used for comparing and judging the data information and the threshold value data when the production line environment is monitored and controlled on line in real time by each monitoring module, if the numerical value does not exceed the threshold value, the control is passed, and if the numerical value exceeds the threshold value, the abnormality alarming module (4) and the environment maintenance module (5) are started.
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN117933725A (en) * | 2024-02-29 | 2024-04-26 | 连云港长久安全咨询服务有限公司 | Management method and system for chemical safety maintenance operation |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN117933725A (en) * | 2024-02-29 | 2024-04-26 | 连云港长久安全咨询服务有限公司 | Management method and system for chemical safety maintenance operation |
CN117933725B (en) * | 2024-02-29 | 2024-08-16 | 连云港长久安全咨询服务有限公司 | Management method and system for chemical safety maintenance operation |
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