CN116942739A - Compound phellodendron bark liquid wet dressing combined silica gel foam dressing for treating pressure sores - Google Patents

Abstract

The invention discloses a compound phellodendron bark liquid wet dressing combined silica gel foam dressing for treating pressure sores, which relates to the technical field of medicine preparation and has the technical scheme that: the preparation method comprises wet dressing of compound phellodendron bark liquid and silica gel foam dressing, wherein the main medicinal components of the compound phellodendron bark liquid comprise fructus forsythiae, phellodendron bark, honeysuckle, dandelion and centipede; the silicone foam dressing includes a wound contact layer, a foam layer, a water barrier layer, and an outer film. Compared with the common method, the method has obvious advantages, is beneficial to improving the quality, initiative, satisfaction and qualification rate of nursing operation, has better effect and is suitable for clinical popularization.

Description

A compound Huangbai liquid wet compress combined with silicone foam dressing for the treatment of pressure ulcers

Technical field

The present invention relates to the technical field of pharmaceutical preparation, and more specifically, it relates to a compound cork solution wet compress combined with silicone foam dressing for the treatment of pressure ulcers.

Background technique

Traditional Chinese medicine believes that pressure ulcers refer to the general term for all suppurative and infectious diseases on the body surface caused by various pathogenic factors attacking the human body, including acute and chronic categories. In ancient China, pressure ulcers were used to refer to a variety of surgical diseases. In later generations, surgical pressure ulcers were mostly caused by internal invasion of poisonous pathogens, pathogenic heat burning the blood, and stagnation of qi and blood. Pressure ulcers, also known as bedsores, are caused by long-term pressure on local skin of the body, which affects blood circulation, leading to a lack of nutrition in the skin and subcutaneous tissue, resulting in damage, ulcers and even necrosis. Research shows that the current pressure ulcer rate among elderly patients is as high as 10.4%. Pressure ulcers are common in elderly patients who are bedridden in intensive care units for long periods of time. Once they occur, if follow-up care and treatment are not adequate, they can easily lead to severe ulceration and infection. Treatment for pressure ulcers usually includes regular changes in position, using a special mattress to relieve pressure, applying topical dressings to help the ulcer heal, and ensuring adequate nutritional intake.

The purpose of caring for elderly patients with severe pressure ulcers (stages III and IV) in the ward is to prolong life, relieve pain, reduce anxiety, serve patients, and provide individual comfort, and strengthen the implementation of nursing service measures, thereby comprehensively improving service quality and promoting clinical nursing. Effectiveness. Strengthening the care of elderly patients with severe pressure ulcers in intensive care units is an important means to create a healthy social environment and promote a healthy lifestyle.

The existing technology uses nursing risk management methods and means to carry out regular nursing observations during the nursing process of elderly patients with severe pressure ulcers (stages III and IV), especially around pressure ulcer prevention and nursing measures, to carry out targeted comprehensive observation and analysis and timely evaluation. The effectiveness of pressure ulcer prevention measures can be used to adjust pressure ulcer care measures in the next stage. The general treatment method is to use iodophor skin disinfectant for local disinfection followed by auxiliary phototherapy and irradiation treatment. After flushing the affected area with physiological saline, soak a sterile cotton ball with iodophor and apply it evenly 3 times, then illuminate it with a red light therapy device for 15-20 minutes, and then cover it with ordinary sterile gauze for intervention. This treatment method takes a long time to take effect, slow recovery, and can easily cause wound infection, skin ulceration, etc.

Contents of the invention

The purpose of the present invention is to provide a compound cork solution wet compress combined with silicone foam dressing for the treatment of pressure ulcers, which has good clinical therapeutic effect and is suitable for clinical promotion and application.

The above technical objectives of the present invention are achieved through the following technical solutions: a compound cork liquid wet compress combined with a silicone foam dressing for the treatment of pressure ulcers, including a compound cork liquid wet compress and a silicone foam dressing. The main medicinal ingredients include forsythia, cork, honeysuckle, dandelion and centipede; the silicone foam dressing includes a wound contact layer, a foam layer, a water-locking layer and an outer film.

The present invention is further configured as follows: the weight parts of each medicinal ingredient in the compound Cortex Phellodendron liquid are respectively 75-85 parts of Forsythia suspensa, 38-43 parts of Cortex Phellodendron, 38-43 parts of Honeysuckle, 38-43 parts of Dandelion, and 2.3-2.3 parts of Centipede. 2.5 servings.

The present invention is further configured as follows: the wound contact layer is porous soft silica gel, the foam layer is water-absorbent polyurethane, the water-locking layer is a cellulose fiber matrix carrying water-absorbent particles, and the outer film is available Thermoplastic polyurethane through which dissolved water vapor passes.

The present invention also provides a method for using compound cork liquid wet compress combined with silicone foam dressing for treating pressure ulcers: use sterile gauze to take 5-10 mL of compound cork liquid (soaked gauze) and cover it on the wound surface. Sterile gauze is added to the size and then covered with a silicone foam dressing over the top.

In summary, the present invention has the following beneficial effects: treating severe pressure ulcers (stages III and IV) in elderly patients through compound cork solution wet compress combined with silicone foam dressing has obvious advantages over ordinary methods and helps to improve the quality of nursing operations. , initiative, satisfaction, and pass rate, it has good clinical treatment effect and is suitable for clinical promotion and application.

Detailed ways

In order to make the purpose, technical solutions and advantages of the present invention more clear, the present invention will be further described in detail below in conjunction with the examples. The schematic embodiments of the present invention and their descriptions are only used to explain the present invention and are not intended to serve as a qualification for the present invention. restrictions.

Example 1: 90 elderly patients (age ≥ 65 years old) with severe pressure ulcers (stages III and IV) were selected as research subjects, and different treatment methods were used to compare the curative effects.

A total of 90 elderly patients (age ≥ 65 years old) with severe pressure ulcers (stages III and IV) admitted to the intensive care unit of Dongzhimen Hospital of Beijing University of Chinese Medicine from January 2019 to December 2020 were selected as the research subjects. The average age of the patients was 75.4±1.78 years old, including 41 males with an average age of 69.4±2.78 years and 49 females with an average age of 78.2±1.78 years. According to the random number table method, they were divided into Chinese medicine group, dressing group and control group, with 30 cases in each group. The grouping situation is shown in Table 1. There was no statistically significant difference in the general information of the three groups of patients (P>0.05). The basic conditions of the research subjects are all stable. Analysis of basic diseases: 118 patients with malignant tumors, 69 patients with blood diseases, and 13 patients with other diseases.

Inclusion criteria: ① Patients are ≥65 years old; ② According to the definition and staging standards of pressure ulcers by the National Pressure Ulcer Advisory Panel (NPUAP), they meet the diagnosis of severe pressure ulcers (stages III and IV) and have received symptomatic and supportive treatment; ③ No life-threatening conditions occurred; ④ The patients and their families understood the clinical treatment plan and voluntarily participated in this clinical study. Exclusion criteria: ① Patients meet the diagnosis of severe pressure ulcers (stages III and IV) and are still receiving active supportive treatment; ② Combined with mental illness.

Table 1 Comparison of gender composition and average age of research subjects in different groups

The patients in the three groups first evaluated the wound condition. If the wound smelled bad, bacterial culture was performed before treatment. The patient's wishes should be fully considered during the treatment process, and any questions the patient has should be answered promptly.

The traditional Chinese medicine group was treated with compound Huangbai liquid wet compress combined with silicone foam dressing. After flushing the affected area with physiological saline, stack 3-5 layers of sterile gauze, soak it with compound cork solution and apply it directly to the affected area. After 10-15 minutes, replace the gauze and continue wet compressing. Repeat 3-5 times. The total time is about 45 to 90 minutes. During the wet compress process, if the patient feels irritation and pain, dilute the solution appropriately; if there is fluid leakage from the wound, wipe it with a saline cotton ball and then apply it with gauze soaked in compound cork solution. After the wet compress is completed, the affected area is covered with silicone foam dressing for intervention.

The dressing group was treated with local disinfection using iodophor skin disinfectant and then covering with silicone foam dressing. After flushing the affected area with normal saline, soak a sterile cotton ball with povidone iodine and apply it evenly 3 times, and then cover it with silicone foam dressing for intervention.

The control group was treated with local disinfection with iodophor skin disinfectant followed by auxiliary phototherapy and irradiation. After flushing the affected area with physiological saline, soak a sterile cotton ball with iodophor and apply it evenly 3 times, then illuminate it with a red light therapy device for 15-20 minutes, and then cover it with ordinary sterile gauze for intervention.

Patients in the three groups were intervened for 14 days, and the length, depth, and area of pressure ulcers were measured daily, and the pressure ulcer staging was re-evaluated on the 7th and 14th days respectively.

Example 2: Observation indicators

(1) Length, depth, and area of pressure ulcers: After one course of treatment (14 days), the changes in length, depth, and area of pressure ulcers in the three groups of patients were calculated. If the length, depth, and area of the pressure ulcer are reduced by 10% to 40%, it is basically healed; if the length, depth, and area of the pressure ulcer are reduced by 40% to 60%, it is significantly healed; if the length, depth, and area of the pressure ulcer are reduced by If it is above 60% and there is no exudate, it means that the treatment is significantly effective.

(2) Nursing satisfaction: evaluated using the nursing satisfaction questionnaire developed by our hospital. The questionnaire includes the patient's attitude, satisfaction and acceptance of pressure ulcer care (divided into very satisfied, satisfied and dissatisfied), and is evaluated after the care. The full score is 100 points, divided into very satisfied (above 90 points), relatively satisfied (70 to 90 points), and dissatisfied (below 70 points).

(3) Incidence of inflammation around pressure ulcers and wound healing rate: After one course of treatment, the incidence of inflammation around pressure ulcers and wound healing rate of the three groups of patients were observed compared with those before treatment.

(4) Treatment recovery rate and complete treatment recovery rate: After 1 course of treatment, observe the treatment recovery rate and complete treatment recovery rate of the three groups of patients compared with before treatment.

(5) Incidence rate of nursing-related adverse events: Observe the incidence rate of nursing-related adverse events in the three groups of patients after 3 days, 7 days and 14 days of treatment, including nursing operation accidents, patient discomfort, patient complaints, etc., and record them in the observation record .

Example 3: Results

As shown in Table 2, the pressure ulcer healing conditions of the three groups of patients were significantly different before and after treatment. There was no statistically significant difference in symptoms before treatment (P>0.05). After systemic treatment, the length, depth, and area of pressure ulcers in the traditional Chinese medicine group decreased by 69%, 59%, and 61%, and the pressure ulcer length and depth in the dressing group , area reduction values (65%, 55%, 59%) were significantly better than the length, depth, and area reduction values of the control group (33%, 40%, 39%), and the differences between the three groups were statistically significant (P<0.05 ). The average onset time of significant reduction in the length, depth, and area of pressure ulcers was also significantly better in the traditional Chinese medicine group (5.7 days) and the excipient group (6.5 days) than in the control group (13.2 days) (P<0.05).

Table 2 Comparison of length, depth, and area reduction of pressure ulcers in different groups

The results of this study show that there is a significant difference in the healing of pressure ulcers between the three groups of patients before and after treatment. The onset time of pressure ulcer wound healing in the traditional Chinese medicine group and the dressing group is significantly better than that in the control group, indicating that compound Huangbai liquid wet compress combined with silicone Foam dressing treatment can significantly shorten the onset of effect and improve wound healing.

As shown in Table 3, there was no statistically significant difference in symptoms between the three groups of patients before treatment (P>0.05). After systemic treatment, the incidence of inflammation around pressure ulcers and the wound healing rate of the three groups of patients were significantly different before and after treatment. . The incidence rate of peripheral inflammation and wound healing rate of pressure ulcers in the traditional Chinese medicine group (19%, 69%) and the dressing group (25%, 55%) were significantly better than those in the control group (33%, 40%). %), the differences among the three groups were statistically significant (P<0.05).

Table 3 Comparison of the incidence of inflammation and wound healing rate around pressure ulcers in different groups

As shown in Table 4, the nursing satisfaction of the traditional Chinese medicine group and dressing group was significantly higher than that of the control group, and the difference was statistically significant (P<0.05).

Table 4 Comparison of nursing satisfaction among different groups of patients

As shown in Table 5, the incidence rate of nursing-related adverse events in the traditional Chinese medicine group (7.9%) and the incidence rate of nursing-related adverse events in the dressing group (6.5%) were lower than those in the control group (15.9%), and the differences between the three groups were statistically significant ( P<0.05).

Table 5 Incidence rates of nursing-related adverse events in different groups of wards

This specific embodiment is only an explanation of the present invention, and it is not a limitation of the present invention. Those skilled in the art can make modifications to this embodiment without creative contribution as needed after reading this specification. However, as long as the rights of the present invention are All requirements are protected by patent law.

Claims (4)

1. A compound cork liquid wet compress combined with a silicone foam dressing for the treatment of pressure ulcers, which is characterized by: comprising a compound cork liquid wet compress and a silicone foam dressing, and the main medicinal ingredients of the compound cork liquid include Forsythia suspensa and Cortex Phellodendron. , honeysuckle, dandelion and centipede; the silicone foam dressing includes a wound contact layer, a foam layer, a water-locking layer and an outer film. 2. A compound cork solution wet compress combined with silicone foam dressing for the treatment of pressure ulcers according to claim 1, characterized in that: the weight parts of each medicinal component in the compound cork solution are 75 Forsythia suspensa. -85 parts, Phellodendron 38-43 parts, Honeysuckle 38-43 parts, Dandelion 38-43 parts, Centipede 2.3-2.5 parts. 3. A compound cork solution wet compress combined with silicone foam dressing for treating pressure ulcers according to claim 1, characterized in that: the wound contact layer is porous soft silicone, and the foam layer is water-absorbent polyurethane , the water-locking layer is a cellulose fiber matrix loaded with water-absorbing particles, and the outer film is a thermoplastic polyurethane that allows soluble water vapor to pass through. 4. A method of using compound cork liquid wet compress combined with silicone foam dressing for treating pressure ulcers according to claim 1, which is characterized in that: use sterile gauze to take 5-10mL compound cork liquid and cover the wound surface On top, add or remove sterile gauze according to the size of the wound, and then cover it with silicone foam dressing.