CN116059135B - Water-blocking and bacteria-blocking skin protective agent and preparation method thereof - Google Patents
Water-blocking and bacteria-blocking skin protective agent and preparation method thereof Download PDFInfo
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- CN116059135B CN116059135B CN202310354797.4A CN202310354797A CN116059135B CN 116059135 B CN116059135 B CN 116059135B CN 202310354797 A CN202310354797 A CN 202310354797A CN 116059135 B CN116059135 B CN 116059135B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/58—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
- A61K8/585—Organosilicon compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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Abstract
The invention belongs to the technical field of skin protectants, and particularly relates to a water-blocking and bacteria-blocking skin protectant and a preparation method thereof. The skin protective agent for resisting water and bacteria comprises the following raw materials in percentage by mass: 1-20% of film agent, 70-90% of volatile solvent, 1-10% of plasticizer and 1-10% of silane coupling agent; the film agent is one or more of phenylpropyl dimethyl silicon alkoxy silicate, trimethyl silicon alkoxy silicate and polymethyl silsesquioxane; the volatile solvent is one or more of siloxane and alkane; the plasticizer is one or more of linear organopolysiloxane, branched organopolysiloxane and cyclic organopolysiloxane. The invention solves the problems of poor water resistance and poor film forming flexibility of the existing skin protective agent, improves the water resistance and bacteria resistance of the product, and has good film forming flexibility.
Description
Technical Field
The invention belongs to the technical field of skin protectants, and particularly relates to a water-blocking and bacteria-blocking skin protectant and a preparation method thereof.
Background
In daily life, the skin often suffers from various wounds, forming small wounds such as bruises, cuts, etc., which are at risk of infection; in addition, for the patients suffering from the incontinence of urine and feces, urine, excrement and other excrement can soak the skin, and the soaked skin is very easy to face the risk of pressure sores under the friction action. Typically, the damaged skin is treated with a skin protectant.
Currently, commonly used skin protectants are gels and liquids. Among them, the gel-type skin protectant is used to protect the skin by applying a film on the skin surface, and is usually added with a irritating ingredient such as ethyl acetate, etc., which gives an irritating smell that is generally unacceptable to the patient, and alcohol is contained in the solvent of the gel-type skin protectant, and when used for a broken wound, severe stinging can make the patient resistant to nursing. The liquid skin protectant has certain waterproof function, can be coated in forms of wiping bars, wiping sheets and the like besides being coated in a spray form so as to meet different clinical demands, but the current liquid skin protectant has poor water resistance and flexibility and needs to be further improved.
Disclosure of Invention
The invention aims to provide a water-blocking and bacteria-blocking skin protective agent, which solves the problems of poor water blocking and poor film forming flexibility of the existing skin protective agent, improves the water-blocking and bacteria-blocking capability of products, has good film forming flexibility and provides a simple and efficient preparation method.
The invention relates to a water-blocking and bacteria-blocking skin protective agent which is prepared from the following raw materials in percentage by mass: 1-20% of film agent, 70-90% of volatile solvent, 1-10% of plasticizer and 1-10% of silane coupling agent.
In the invention, the film agent is one or two of phenylpropyl dimethyl siloxysilicate, trimethylsiloxysilicate and polymethylsilsesquioxane.
In the invention, the volatile solvent is one or two of siloxane and alkane.
Preferably, the siloxane is a linear or cyclic siloxane having 2-7 silicon atoms and has a viscosity of 0.65cst or less. Volatile silicones that can be used in the present invention include, but are not limited to: hexamethyldisiloxane, heptamethylhexyltrisiloxane, heptamethyloctyltrisiloxane, octamethyltrisiloxane, octamethylcyclotetrasiloxane, decamethyltetrasiloxane, decamethylcyclopentasiloxane, dodecamethylcyclohexasiloxane, and dodecamethylpentasiloxane.
Preferably, the alkane is an alkane having from 4 to 16 carbon atoms. Alkanes that may be used in the present invention include, but are not limited to: n-butane, cyclohexane, n-hexane, n-heptane, isooctane, isododecane, isodecane, isohexadecane.
In the present invention, the plasticizer is an organopolysiloxane from low viscosity to high viscosity, preferably one or more of a linear organopolysiloxane, a cyclic organopolysiloxane, and a branched organopolysiloxane.
Preferably, the linear organopolysiloxane is one or more of dimethylpolysiloxane, octylpolymethylsiloxane, phenyl polytrimethylsiloxane, methylphenyl polysiloxane, methylhexyl polysiloxane, methyl hydrogen polysiloxane, dimethyl siloxane-methylphenyl siloxane copolymer.
Preferably, the cyclic organopolysiloxane is one or more of octamethyl cyclotetrasiloxane, decamethyl cyclopentasiloxane, dodecamethyl cyclotetrasiloxane, tetramethyl tetrahydrocyclotetrasiloxane, tetramethyl tetraphenyl cyclotetrasiloxane.
Preferably, the branched organopolysiloxane is one or more of methyltri (trimethylsiloxy) silane, tetra (trimethylsiloxy) silane, amino modified organopolysiloxane, pyrrolidone carboxylic acid modified organopolysiloxane.
In the invention, the silane coupling agent is one or more of vinyl triethoxysilane, vinyl trimethoxysilane, vinyl tri (beta-methoxyethoxy) silane, 3-glycidoxypropyl triethoxysilane, 3- (methacryloyloxy) propyl trimethoxysilane, aminopropyl triethoxysilane, aminopropyl trimethoxysilane, allyl triethoxysilane, allyl trimethoxysilane, N- (2-aminoethyl) -3-aminopropyl trimethoxysilane, N-aminoethyl-3-aminopropyl methyldimethoxy silane, anilinomethyl triethoxysilane and phenyl triethoxysilane.
The preparation method of the water-blocking bacteria-blocking skin protective agent comprises the following steps:
firstly mixing the film agent with the plasticizer, then adding the silane coupling agent, stirring and mixing for 10-60min at room temperature, finally adding the volatile solvent, and stirring for 5-30min at room temperature to obtain the water-blocking and bacteria-blocking skin protectant.
Compared with the prior art, the invention has the following beneficial effects:
the skin protective agent disclosed by the invention adopts the organic siloxane polymer with stronger film forming property as a film agent, improves the water-blocking and bacteria-blocking capacity of a product, adopts one or a mixture of more of siloxane or alkane as a volatile solvent, adopts linear, branched or cyclic organopolysiloxane as a plasticizer, improves the flexibility after film forming, and improves the bonding strength of the film agent and the plasticizer through a silane coupling agent, and the components interact, so that the water-blocking and bacteria-blocking capacity and the film forming flexibility of the product are improved, and the problems of poor water blocking and poor film forming flexibility of the conventional skin protective agent are solved.
Detailed Description
The invention is further illustrated below with reference to examples. The raw materials used in the examples, unless otherwise specified, were all commercially available conventional raw materials; the process used in the examples, unless otherwise specified, is conventional in the art.
The raw material formulations (in mass%) of examples 1 to 6 and comparative examples 1 to 3 are shown in Table 1.
Table 1 raw material formulations of examples 1-6 and comparative examples 1-3
Example 1
According to the raw material formula of Table 1, firstly mixing the film agent with the plasticizer, then adding the silane coupling agent, stirring and mixing for 30min at room temperature, finally adding the volatile solvent, and stirring for 15min at room temperature to obtain the water-blocking and bacteria-blocking skin protectant.
Example 2
According to the raw material formula of Table 1, firstly mixing the film agent with the plasticizer, then adding the silane coupling agent, stirring and mixing for 10min at room temperature, finally adding the volatile solvent, and stirring for 5min at room temperature to obtain the water-blocking and bacteria-blocking skin protectant.
Example 3
According to the raw material formula of Table 1, firstly mixing the film agent with the plasticizer, then adding the silane coupling agent, stirring and mixing for 20min at room temperature, finally adding the volatile solvent, and stirring for 10min at room temperature to obtain the water-blocking and bacteria-blocking skin protectant.
Example 4
According to the raw material formula of Table 1, firstly mixing the film agent with the plasticizer, then adding the silane coupling agent, stirring and mixing for 30min at room temperature, finally adding the volatile solvent, and stirring for 20min at room temperature to obtain the water-blocking and bacteria-blocking skin protectant.
Example 5
According to the raw material formula of Table 1, firstly mixing the film agent with the plasticizer, then adding the silane coupling agent, stirring and mixing for 50min at room temperature, finally adding the volatile solvent, and stirring for 25min at room temperature to obtain the water-blocking and bacteria-blocking skin protectant.
Example 6
According to the raw material formula of Table 1, firstly mixing the film agent with the plasticizer, then adding the silane coupling agent, stirring and mixing for 60min at room temperature, finally adding the volatile solvent, and stirring for 30min at room temperature to obtain the water-blocking and bacteria-blocking skin protectant.
The preparation method of comparative examples 1 to 3 is the same as that of example 1.
The skin protectants prepared in each example and comparative example were subjected to performance testing, and the test methods and results were as follows:
1. film forming time test:
uniformly applying the skin protectant liquid on filter paper with application amount of 1.0g/cm 2 The drying time of the liquid was tested as film forming time with hands or gloves as the drying point. The test results are shown in Table 2.
TABLE 2 film formation time test results
As can be seen from table 2: the skin protectants of examples 1-6 all had film formation times within 120 seconds, and the greater the plasticizer content, the longer the film formation time, and the higher the octamethyltrisiloxane content, the longer the film formation time. In the comparative example 1, no silane coupling agent is added, the components have no interaction, the solvent volatilization speed is high, and the film forming time is short; in comparative examples 2 and 3, no plasticizer and film agent were added, respectively, the solvent volatilization speed was high, and the film forming time was short.
2. And (3) water resistance performance test:
uniformly applying the skin protectant liquid on filter paper with application amount of 1.0g/cm 2 After the sample is dried (without hands or gloves), the prepared sample is used as a test sample and has no wrinkles; filling the test pool with purified water at the temperature of (21+/-2), placing the sample on the lower ring in a horizontal sliding mode, avoiding air between the surface of the water and the lower surface of the sample, covering the upper surface of the sample with dry filter paper with the area larger than the test area, placing the upper ring, and clamping by using a screw thread device; injecting water into the tube to a desired level above the surface of the sample, maintaining the hydrostatic pressure (300.+ -.10) s; the filter paper was checked for water penetration through the sample and the results were recorded. The test results are shown in Table 3.
TABLE 3 Water blocking Performance test results
As can be seen from table 3: the skin protectants of examples 1-6 exhibited water blocking properties ranging from 300 to 600mm water column, with greater amounts of film, plasticizer and silane coupling agent providing good water blocking properties. In comparative example 1, the silane coupling agent is not added, the bonding strength of the film agent and the plasticizer is weak, and the strength after film formation is poor, so that the water resistance is poor; in comparative example 2, no plasticizer is added, and toughness is not provided after film formation, so that water cannot be blocked; in comparative example 3, no film agent was added, and film formation was impossible after the solvent was volatilized, resulting in failure to block water.
3. And (3) testing the bacterial resistance:
uniformly applying the liquid on the filter paper with the application amount of 1.0g/cm 2 After the sample is dried (without hands or gloves), the prepared sample is used as a test sample and has no wrinkles; 3 samples are taken, the film forming surface of the samples faces the sampling chamber, the samples are clamped between the challenge chamber and the sampling chamber, the clamping mode is confirmed, leakage of challenge microorganisms is guaranteed not to occur, and the rest part of the samples with large area can be cut off or wrapped around the experimental device.
(1) Adding challenge microorganisms: the challenge inoculums are smeared by a sterile swab and inoculated on the outer surface of the sample through a challenge chamber port, and are smeared uniformly as much as possible;
(2) Adding a nutrient broth: filling the sampling chamber with nutrient broth in a sterile manner;
(3) Sample challenge: closing the challenge chamber port and the sampling chamber port of the test device in a proper mode, ensuring that no external pollution is generated, and placing the test device into a 26 ℃ incubator for 24 hours;
(4) Penetration microbiological examination: after a prescribed period of time, the growth of microorganisms in the nutrient broth is visually observed;
(5) Challenge microbial viability assay: after a prescribed period of time, the sterile swab was pre-moistened in sterile saline and excess water was squeezed off, the outer surface of the sample was wiped through the challenge chamber port, then inoculation was performed by wiping the surface of the nutrient agar plates, three sterile swabs were used for each sample, each sample was inoculated on three nutrient agar plates, and the swabs were rotated multiple times during this period. The nutrient agar plates were incubated at 26℃for 24h and checked for challenging microbial viability. The test results are shown in Table 4, wherein "+" indicates bacterial growth and "-" indicates no bacterial growth.
TABLE 4 antibacterial property test results
As can be seen from table 4: the skin protectants of examples 1-6 all have antibacterial properties. In comparative example 1, the combination strength of the film agent and the plasticizer is weak without adding the silane coupling agent, and the strength after film formation is poor, so that the antibacterial performance is poor; in comparative example 2, no plasticizer is added, and toughness is not provided after film formation, so that bacteria cannot be blocked; in comparative example 3, film forming was impossible after the solvent was volatilized without adding a film agent, resulting in failure to inhibit bacteria.
4. Durability test:
applying toluidine blue on skin surface, drying, applying skin protectant on skin surface, and covering with toluidineBlue application area, drying completely, and applying 20mg/cm (without hand or glove) 2 To the area to be tested, then the area to be tested was massaged by hand for 2s, a commercially available white dust-free cloth of a certain thickness was applied to the coated area for 5s with a force of 100g/f, and the white dust-free cloth was checked for the presence of toluidine blue, if no toluidine blue indicates that the durability of the article was good. The test results are shown in Table 5.
Table 5 durability test results
As can be seen from table 5: the skin protectants of examples 1-6 all passed the persistence test. In comparative example 1, the silane coupling agent is not added, the bonding strength of the film agent and the plasticizer is weak, the strength after film formation is poor, and the durability is poor; in comparative example 2, no plasticizer was added, and there was no toughness after film formation, resulting in poor durability; in comparative example 3, film formation was impossible after solvent evaporation without adding a film forming agent.
5. Flexibility test:
applying toluidine blue on skin surface of elbow, drying, applying skin protectant to skin surface, covering toluidine blue application area, completely drying, stretching arm for 50 times, and applying (without hand or glove) 20mg/cm 2 To the area to be tested, a commercially available white dust-free cloth of a certain thickness was applied to the coated area with a force of 100g/f for 5s, and the white dust-free cloth was checked for toluidine blue, if no toluidine blue indicates that the flexibility of the product was good. The test results are shown in Table 6.
TABLE 6 flexibility test results
As can be seen from table 6: the skin protectants of examples 1-6 all passed the flexibility test. In comparative example 1, the film agent and the plasticizer are weak in bonding strength without adding a silane coupling agent, and the flexibility after film formation is poor; in comparative example 2, no plasticizer was added, and no toughness was observed after film formation; in comparative example 3, film formation was impossible after solvent evaporation without adding a film forming agent.
Claims (4)
1. A water-blocking bacteria-blocking skin protectant, characterized in that: the material comprises the following raw materials in percentage by mass: 1-20% of film agent, 70-90% of volatile solvent, 1-10% of plasticizer and 1-10% of silane coupling agent;
the film agent is one or more of phenylpropyl dimethyl silicon alkoxy silicate, trimethyl silicon alkoxy silicate and polymethyl silsesquioxane;
the volatile solvent is one or two of siloxane and alkane; wherein the siloxane is a linear or cyclic siloxane having 2 to 7 silicon atoms; the alkane is an alkane having 4 to 16 carbon atoms;
the plasticizer is one or more of linear organopolysiloxane, branched organopolysiloxane and cyclic organopolysiloxane;
the silane coupling agent is one or more of vinyl triethoxysilane, vinyl trimethoxysilane, vinyl tri (beta-methoxyethoxy) silane, 3-glycidoxy propyl triethoxysilane, 3- (methacryloyloxy) propyl trimethoxysilane, aminopropyl triethoxysilane, aminopropyl trimethoxysilane, allyl triethoxysilane, allyl trimethoxysilane, N- (2-aminoethyl) -3-aminopropyl trimethoxysilane, N-aminoethyl-3-aminopropyl methyl dimethoxy silane, anilinomethyl triethoxysilane and phenyl triethoxysilane.
2. The water-blocking and bacteria-blocking skin protectant of claim 1, wherein: the linear organopolysiloxane is one or more of dimethyl polysiloxane, octyl polymethylsiloxane, phenyl polytrimethylsiloxane, methylphenyl polysiloxane, methyl hexyl polysiloxane, methyl hydrogen polysiloxane and dimethyl siloxane-methylphenyl siloxane copolymer;
the cyclic organopolysiloxane is one or more of octamethyl cyclotetrasiloxane, decamethyl cyclopentasiloxane, dodecamethyl cyclohexasiloxane, tetramethyl tetrahydrocyclotetrasiloxane and tetramethyl tetraphenyl cyclotetrasiloxane.
3. The water-blocking and bacteria-blocking skin protectant of claim 1, wherein: the branched organopolysiloxane is one or more of methyltri (trimethylsiloxy) silane, tetra (trimethylsiloxy) silane, amino-modified organopolysiloxane, pyrrolidone carboxylic acid-modified organopolysiloxane.
4. A method for preparing the water-blocking and bacteria-blocking skin protectant according to any one of claims 1-3, characterized in that: firstly mixing the film agent with the plasticizer, then adding the silane coupling agent, stirring and mixing for 10-60min at room temperature, finally adding the volatile solvent, and stirring for 5-30min at room temperature to obtain the water-blocking and bacteria-blocking skin protectant.
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101405345A (en) * | 2005-04-06 | 2009-04-08 | 陶氏康宁公司 | Organosiloxane compositions |
| CN101980693A (en) * | 2007-12-05 | 2011-02-23 | 莱雅公司 | Cosmetic make-up and/or care method using a siloxane resin and a non-volatile oil |
| CN103113824A (en) * | 2013-01-18 | 2013-05-22 | 中科院广州化学有限公司 | Film-forming polysiloxane emulsion and preparation method thereof |
| CN103608384A (en) * | 2011-05-30 | 2014-02-26 | 道康宁东丽株式会社 | Novel liquid organo polysiloxane and use therefor |
| CN109431862A (en) * | 2018-12-10 | 2019-03-08 | 广州艾蓓生物科技有限公司 | A kind of lasting eyeliner |
| CN113786357A (en) * | 2021-09-16 | 2021-12-14 | 广州环亚化妆品科技有限公司 | Gel with sun-proof, instant and long-acting wrinkle-smoothing effects and preparation method thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7758848B2 (en) * | 2004-10-22 | 2010-07-20 | L'oreal | Cosmetic composition containing a polyorganosiloxane polymer |
| GB0506939D0 (en) * | 2005-04-06 | 2005-05-11 | Dow Corning | Organosiloxane compositions |
| US7790148B2 (en) * | 2005-09-02 | 2010-09-07 | L'oreal | Compositions containing silicone polymer, wax and volatile solvent |
| KR102653544B1 (en) * | 2015-10-05 | 2024-04-03 | 듀폰 도레이 스페셜티 머티리얼즈 가부시키가이샤 | Oil-in-water organopolysiloxane emulsion, manufacturing method thereof, cosmetic raw materials and cosmetics |
| WO2019003898A1 (en) * | 2017-06-28 | 2019-01-03 | 東レ・ダウコーニング株式会社 | Film-forming agent for cosmetics and cosmetics containing same |
-
2023
- 2023-04-06 CN CN202310354797.4A patent/CN116059135B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101405345A (en) * | 2005-04-06 | 2009-04-08 | 陶氏康宁公司 | Organosiloxane compositions |
| CN101980693A (en) * | 2007-12-05 | 2011-02-23 | 莱雅公司 | Cosmetic make-up and/or care method using a siloxane resin and a non-volatile oil |
| CN103608384A (en) * | 2011-05-30 | 2014-02-26 | 道康宁东丽株式会社 | Novel liquid organo polysiloxane and use therefor |
| CN103113824A (en) * | 2013-01-18 | 2013-05-22 | 中科院广州化学有限公司 | Film-forming polysiloxane emulsion and preparation method thereof |
| CN109431862A (en) * | 2018-12-10 | 2019-03-08 | 广州艾蓓生物科技有限公司 | A kind of lasting eyeliner |
| CN113786357A (en) * | 2021-09-16 | 2021-12-14 | 广州环亚化妆品科技有限公司 | Gel with sun-proof, instant and long-acting wrinkle-smoothing effects and preparation method thereof |
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