CN115744007A - Automatic slide supplying and taking device - Google Patents
Automatic slide supplying and taking device Download PDFInfo
- Publication number
- CN115744007A CN115744007A CN202211469095.2A CN202211469095A CN115744007A CN 115744007 A CN115744007 A CN 115744007A CN 202211469095 A CN202211469095 A CN 202211469095A CN 115744007 A CN115744007 A CN 115744007A
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- Prior art keywords
- slide
- magazine
- storehouse
- door
- feeding
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- 238000001514 detection method Methods 0.000 claims abstract description 12
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- 239000011521 glass Substances 0.000 description 11
- 210000000349 chromosome Anatomy 0.000 description 8
- 238000004458 analytical method Methods 0.000 description 4
- 238000003745 diagnosis Methods 0.000 description 4
- 230000031864 metaphase Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- IAKHMKGGTNLKSZ-INIZCTEOSA-N (S)-colchicine Chemical compound C1([C@@H](NC(C)=O)CC2)=CC(=O)C(OC)=CC=C1C1=C2C=C(OC)C(OC)=C1OC IAKHMKGGTNLKSZ-INIZCTEOSA-N 0.000 description 2
- 108010047620 Phytohemagglutinins Proteins 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 210000004698 lymphocyte Anatomy 0.000 description 2
- 230000001885 phytohemagglutinin Effects 0.000 description 2
- 230000035519 G0 Phase Effects 0.000 description 1
- 230000010190 G1 phase Effects 0.000 description 1
- 208000026350 Inborn Genetic disease Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 239000006285 cell suspension Substances 0.000 description 1
- 238000003759 clinical diagnosis Methods 0.000 description 1
- 229960001338 colchicine Drugs 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 208000016361 genetic disease Diseases 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 210000003917 human chromosome Anatomy 0.000 description 1
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- 230000011278 mitosis Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
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- 210000005259 peripheral blood Anatomy 0.000 description 1
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Images
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- Investigating Or Analysing Biological Materials (AREA)
Abstract
The invention relates to an automatic slide supplying and taking device, which belongs to the field of biological detection and comprises a control device, a slide library, a plurality of slide bins and a plurality of slide clips, wherein a stepping motor and a plurality of movable seats are arranged in the slide library, the movable seats are respectively in transmission connection with the stepping motor, the slide bins are arranged on the movable seats, the slide clips are uniformly arranged on slide clip chutes in the slide bins and are detachably connected with the slide bins, a plurality of slide clamping grooves for placing slides are arranged on the slide clips, bin gates adaptive to the sizes and the shapes of the slide clips are also arranged on the slide library, and the stepping motor is electrically connected with the control device, so that the automatic supply and taking of slides can be realized, the operation time can be greatly reduced, and the working efficiency of doctors is improved.
Description
Technical Field
The invention relates to an automatic slide supplying and taking device, and belongs to the field of biological detection.
Background
Lymphocytes in peripheral blood are almost in the G0 or G1 phase and are generally not dividing. When Phytohemagglutinin (PHA) is added to the culture medium, such small lymphocytes are stimulated to be transformed into lymphoblasts and start mitosis. After short-term culture, a large number of metaphase cells can be obtained by treatment with colchicine, and after flaking, chromosomes can be clearly observed and analyzed.
In the diagnosis technology of the chromosome genetic disease, the only standard diagnosis method is the chromosome karyotype analysis technology, namely, the metaphase of the chromosome of the patient is directly shot, observed and analyzed through a microscope, and the chromosome information of the patient is judged by comparing with the ISCN international standard. In clinical diagnosis in hospitals and third-party medical laboratories, digital microscopes are often used to observe slides coated with cell suspensions, observe and photograph metaphase division items and the like of chromosomes, and then perform manual analysis or automatic software analysis on the obtained pictures. The chromosome analysis process only needs a great deal of work time of a doctor (30-50 minutes of human-computer interaction analysis/patient), and a clinician is invested in full time and can only analyze chromosome information of 10 patients every day, so that a great deal of patients are accumulated.
Therefore, a rapid, intelligent and accurate human chromosome automatic auxiliary analysis and diagnosis device for accelerating diagnosis and treatment efficiency and improving clinical service level is a technical problem to be solved by the technical personnel in the field.
Disclosure of Invention
In view of this, the invention provides an automatic slide supplying and taking device, which can realize automatic supply and taking of slides, greatly reduce operation time and improve working efficiency of doctors.
The technical scheme for solving the technical problems is as follows:
an automatic slide supplying and taking device comprises a control device, a slide library, a plurality of slide bins and a plurality of slide clamps,
be provided with step motor and a plurality of sliding seat in the slide storehouse, it is a plurality of the sliding seat respectively with the step motor transmission is connected, the slide storehouse sets up on the sliding seat, it is a plurality of the slide presss from both sides evenly to be set up on the slide spout in the slide storehouse and with the slide storehouse can be dismantled and be connected, the slide presss from both sides to have a plurality of slide draw-in grooves of placing the slide, still have on the slide storehouse with the door that the size of slide clamp and shape adapted, step motor with the controlling means electricity is connected.
On the basis of the technical scheme, the invention can be improved as follows.
Further, the inside circuit board that keeps away from in slide storehouse one side of door still is provided with, the circuit board with controlling means electricity is connected, have a plurality ofly on the circuit board with the micro-gap switch that slide holder spout quantity, position correspond, micro-gap switch's both sides have piece storehouse magnet respectively, have on the slide clamp with the piece that piece storehouse magnet corresponds presss from both sides magnet.
Further, a handle is arranged at the top of the slide bin.
Furthermore, a sheet clamp magnet is also arranged at the corresponding position of one side of the glass sheet clamp, which is far away from the sheet clamp magnet.
Further, slide storehouse lateral wall has a plurality of limiting plates, the inside wall of sliding seat has spacing track, spacing track end has the piece storehouse draw-in groove, the slide storehouse passes through the limiting plate with the piece storehouse draw-in groove with the connection can be dismantled to the sliding seat.
Further, the sliding seat is provided with a card bin on-line detection sensor clamping groove, and a card bin on-line detection sensor is arranged in the card bin on-line detection sensor clamping groove and used for detecting the state of the slide bin.
Furthermore, one side of the slide clamping groove is also provided with a sliding spring clamping seat.
Further, the device also comprises a bin gate sensor, wherein the sensor is arranged at the bin gate and used for detecting the state of the bin gate.
The beneficial effects of the invention are:
1. scanning is quick: the special mechanical structure design can enable the device to quickly load and unload the slide;
2. manpower is saved: the slide sample is not required to be taken and placed manually like the traditional mode, so that the labor is greatly saved, and the burden of doctors is relieved.
Drawings
FIG. 1 is a schematic view showing the construction of an automatic slide supplying and taking apparatus according to the present invention;
FIG. 2 is a schematic view showing the structure of the back side of the automatic slide feeder of the present invention;
FIG. 3 is a schematic view of a slide magazine configuration of the present invention;
fig. 4 is a schematic view of a glass clip structure according to the present invention.
In the drawings, the components represented by the respective reference numerals are listed below:
1. slide storehouse, 11, step motor, 12, sliding seat, 13, door, 2, slide storehouse, 21, slide holder spout, 22, handle, 23, limiting plate, 3, slide holder, 31, slide holder magnet, 32, slide spring cassette, 4, slide.
Detailed Description
The principles and features of this invention are described below in conjunction with the following drawings, which are set forth by way of illustration only and are not intended to limit the scope of the invention.
As shown in fig. 1-4, the automatic slide supplying and taking device comprises a control device, a slide library 1, a plurality of slide bins 2 and a plurality of slide holders 3, preferably, 2-6 slide bins 2 are arranged in each slide library 1, 25 slide holders 3 are arranged in each slide bin 2, and each slide holder 3 can carry 4 slides 4;
be provided with step motor 11 and a plurality of sliding seat 12 in the slide storehouse 1, the quantity of sliding seat 12 corresponds with slide storehouse 2 quantity, a plurality of sliding seats 12 are connected with step motor 11 transmission respectively, slide storehouse 2 sets up on sliding seat 12, a plurality of slide presss from both sides 3 and evenly sets up on slide clamp spout 21 in slide storehouse 2 and can dismantle with slide storehouse 2 and be connected, 3 quantity less than or equal to slide clamp spout 21 quantity of slide clamp, the slide clamp has a plurality of slide draw-in grooves of placing slide 4 on 3, 4 quantity less than or equal to slide draw-in groove quantity of slide, still have the door 13 with 3 size and the shape adaptations of slide clamp on the slide storehouse 1, step motor 11 is connected with controlling means electricity.
In another embodiment of the present invention, a circuit board is further disposed on one side of the interior of the slide magazine 2 away from the magazine door 13, the circuit board is electrically connected to the control device, the circuit board has a plurality of micro switches corresponding to the number and positions of the slide clamp chutes 21, the two sides of the micro switches respectively have slide magazine magnets, and the slide clamp 3 has a slide clamp magnet 31 corresponding to the slide magazine magnets.
In another embodiment of the invention, the top of the slide glass bin 2 is provided with a handle 22, which is convenient for an operator to take and place the slide glass bin, when the operator places a slide glass and a slide glass clip to prepare for putting the slide glass bin on a corresponding position on the movable seat, the operator needs to hold the handle on the slide glass bin by hand, move the slide glass bin right above the movable seat, and then correspond the limiting plate on the slide glass bin to the limiting rail on the movable seat and lightly place the slide glass bin to the bottom.
In another embodiment of the present invention, slide holder 3 is also provided with a slide holder magnet 31 at a position corresponding to a side remote from slide holder magnet 31.
In another embodiment of the invention, the outer side wall of the slide chamber 2 is provided with a plurality of limiting plates 23, the inner side wall of the movable seat 12 is provided with a limiting track, the tail end of the limiting track is provided with a slide chamber clamping groove, and the slide chamber 2 is detachably connected with the movable seat 12 through the limiting plates and the slide chamber clamping grooves.
In another embodiment of the present invention, the movable seat 12 has a card slot for the slide magazine in-place detection sensor, and the card slot for the slide magazine in-place detection sensor is provided with the slide magazine in-place detection sensor for detecting the state of the slide magazine 2.
In another embodiment of the invention, one side of the slide card slot also has a slide spring retainer 32.
In another embodiment of the present invention, a door 13 sensor is further included, and the sensor is disposed at the door 13 to detect a state of the door 13.
The working principle of the invention is as follows: the method comprises the steps of placing a slide 4 in a slide clamp 3 in advance, loading the slide clamp 3 to a slide bin 2, when the slide clamp normally extends into a gap of the slide bin, enabling magnets on two sides of a microswitch in the gap of the slide bin to be opposite to two magnets on the slide clamp and attracting each other due to magnetic force, enabling the microswitch to be pressed by the slide clamp at the moment, observing that no slide clamp protrudes when sight lines are perpendicular to the side face of the slide bin, indicating that the slide clamp is correctly placed in the slide bin, placing the slide bin 2 in a slide bin 1, starting equipment, enabling a stepping motor 11 to adjust the position of a movable seat 12, enabling the slide clamp 3 to be detected to move to a bin door 13, taking out the slide clamp 3 by using a special machine, detecting, returning the slide clamp 3 after detection is finished, enabling the stepping motor 11 to work, moving the undetected slide clamp 3 to the bin door 13 again, and monitoring taking and taking information and opening and closing states of the slide clamp 3 in real time by using a sensor.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.
Claims (8)
1. An automatic slide supplying and taking device is characterized by comprising a control device, a slide library, a plurality of slide bins and a plurality of slide clamps,
be provided with step motor and a plurality of sliding seat in the slide storehouse, it is a plurality of the sliding seat respectively with the step motor transmission is connected, the slide storehouse sets up on the sliding seat, it is a plurality of the slide presss from both sides evenly to be set up on the slide spout in the slide storehouse and with the slide storehouse can be dismantled and be connected, the slide presss from both sides to have a plurality of slide draw-in grooves of placing the slide, still have on the slide storehouse with the door that the slide pressed from both sides size and shape adaptation, step motor with the controlling means electricity is connected.
2. The automatic slide supplying and taking device according to claim 1, wherein a circuit board is further disposed on a side of the interior of the slide magazine away from the magazine door, the circuit board is electrically connected to the control device, the circuit board has a plurality of micro switches corresponding to the number and positions of the slide slots, the micro switches have slide magazine magnets on both sides thereof, and the slide clips have slide clip magnets corresponding to the slide magazine magnets.
3. The automated slide feeding and retrieving device of claim 2, wherein the slide magazine top has a handle.
4. The automated slide feeding and retrieving device of claim 2, wherein a slide holder magnet is also provided on a side of the slide holder remote from the slide holder magnet.
5. The automated slide feeding and taking device of claim 1, wherein the slide magazine has a plurality of limiting plates on an outer sidewall thereof, the movable base has a limiting rail on an inner sidewall thereof, the limiting rail has a magazine slot at an end thereof, and the slide magazine is detachably connected to the movable base via the limiting plates and the magazine slot.
6. The automated slide feeding and retrieving device of claim 1, wherein the movable base has a slide magazine in-place detection sensor slot, and a slide magazine in-place detection sensor is disposed in the slide magazine in-place detection sensor slot for detecting a state of the slide magazine.
7. The automated slide feeding and removing device of claim 1, wherein one side of the slide channel further has a slide spring catch.
8. The automated slide feeding and retrieving device of claim 1, further comprising a door sensor disposed at the door for detecting a status of the door.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211469095.2A CN115744007A (en) | 2022-11-22 | 2022-11-22 | Automatic slide supplying and taking device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211469095.2A CN115744007A (en) | 2022-11-22 | 2022-11-22 | Automatic slide supplying and taking device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115744007A true CN115744007A (en) | 2023-03-07 |
Family
ID=85335250
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211469095.2A Pending CN115744007A (en) | 2022-11-22 | 2022-11-22 | Automatic slide supplying and taking device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN115744007A (en) |
-
2022
- 2022-11-22 CN CN202211469095.2A patent/CN115744007A/en active Pending
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