CN115530889B - Tumor sampling equipment convenient for separating tumor - Google Patents
Tumor sampling equipment convenient for separating tumor Download PDFInfo
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- CN115530889B CN115530889B CN202211393828.9A CN202211393828A CN115530889B CN 115530889 B CN115530889 B CN 115530889B CN 202211393828 A CN202211393828 A CN 202211393828A CN 115530889 B CN115530889 B CN 115530889B
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- 238000005070 sampling Methods 0.000 title claims abstract description 113
- 206010028980 Neoplasm Diseases 0.000 title claims abstract description 64
- 238000001514 detection method Methods 0.000 claims abstract description 15
- 230000005540 biological transmission Effects 0.000 claims description 106
- 230000000149 penetrating effect Effects 0.000 claims description 3
- 238000002955 isolation Methods 0.000 claims 2
- 238000000034 method Methods 0.000 abstract description 13
- 230000008569 process Effects 0.000 abstract description 12
- 239000007788 liquid Substances 0.000 description 5
- 239000012530 fluid Substances 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 238000006073 displacement reaction Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000005096 rolling process Methods 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 238000003556 assay Methods 0.000 description 1
- 230000004663 cell proliferation Effects 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 231100000588 tumorigenic Toxicity 0.000 description 1
- 230000000381 tumorigenic effect Effects 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0233—Pointed or sharp biopsy instruments
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0233—Pointed or sharp biopsy instruments
- A61B10/0266—Pointed or sharp biopsy instruments means for severing sample
- A61B10/0275—Pointed or sharp biopsy instruments means for severing sample with sample notch, e.g. on the side of inner stylet
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/10—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis
- A61B90/11—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis with guides for needles or instruments, e.g. arcuate slides or ball joints
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- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
The application belongs to the technical field of medical sampling equipment, and particularly relates to tumor sampling equipment convenient for separating tumors, which comprises a fixed shell, wherein a puncture handle is fixedly connected to the side wall of the fixed shell, one end of the fixed shell, which is close to the puncture handle, is connected with a puncture depth detection unit, one end of the fixed shell, which is far away from the puncture depth detection unit, is provided with a sampling end, the sampling end is connected with a puncture needle assembly, one end of the puncture needle assembly, which is far away from the sampling end, is provided with a puncture end, one end of the puncture needle assembly, which is far away from the puncture end, passes through the sampling end and is positioned in the fixed shell, a first cavity is formed in the fixed shell, a driving unit is arranged in the first cavity, the puncture needle assembly drives sampling through the driving unit, an auxiliary sampling unit is communicated in the puncture needle assembly, and the auxiliary sampling unit is used for assisting the driving unit in sampling and is convenient for releasing samples. The application can automatically intercept tumor samples and release tumor samples, accurately grasp the puncture depth, and ensure that the whole sampling process is smoother and more stable.
Description
Technical Field
The application belongs to the technical field of medical sampling equipment, and particularly relates to tumor sampling equipment convenient for separating tumors.
Background
The tumor is a new organism formed by local tissue cell proliferation under the action of various tumorigenic factors, and because the new organism is a plurality of occupied massive protrusions, also called neoplasms, a doctor is required to perform assay detection on tumor samples by using a sampling device when judging whether the tumor is benign or malignant. However, the existing sampling equipment sucks tumor tissues through negative pressure, so that the method has small wound and alleviates the pain of a patient, the traditional needle tube sampling is not easy to succeed once by singly relying on negative pressure, the adsorption process is not accurate enough, the puncture process is not stable enough, the intercepted sample is not easy to separate, the manual separation is also needed, and the whole sampling process is complicated; therefore, there is a need for a tumor sampling device that can automatically intercept and release tumor samples, and accurately grasp the penetration depth, so that the whole sampling process is smoother and more stable, and can conveniently separate tumors.
Disclosure of Invention
The application aims to provide tumor sampling equipment which is convenient for separating tumors, so as to solve the problems and achieve the aim of effectively improving the sampling stability and accuracy.
In order to achieve the above object, the present application provides the following solutions: the utility model provides a tumour sampling equipment of convenient separation tumour, includes fixed casing, fixedly connected with puncture handle on fixed casing's the lateral wall, fixed casing is close to puncture handle's one end is connected with puncture degree of depth detecting element, fixed casing keeps away from puncture degree of depth detecting element's one end sets up to the sampling end, the sampling end is connected with the pjncture needle assembly, the pjncture needle assembly is kept away from the one end of sampling end sets up to the pjncture end, the pjncture needle assembly is kept away from the one end of pjncture end passes the sampling end and is located in the fixed casing, first cavity has been seted up in the fixed casing, be provided with drive unit in the first cavity, the pjncture needle assembly passes through drive unit drive sample, the intercommunication has auxiliary sampling unit in the pjncture needle assembly, auxiliary sampling unit is used for assisting drive unit sample and still be convenient for release sample.
Preferably, the puncture needle assembly comprises an outer needle assembly and an inner needle assembly, the outer needle assembly is sleeved on the outer side of the inner needle assembly, one end, far away from the puncture end, of the outer needle assembly is detachably connected to the sampling end, the inner needle assembly penetrates through the sampling end and is located at one end in the fixed shell and is in transmission connection with the output end of the driving unit, and the auxiliary sampling unit penetrates through the outer needle assembly and is communicated with the inner needle assembly.
Preferably, the inner needle assembly comprises a sliding rod assembly, a transmission needle core and an inner sampling needle head which are sequentially and fixedly connected, the sliding rod assembly is in transmission connection with the output end of the driving unit, the sliding rod assembly rotates and moves along the sampling direction, the transmission needle core penetrates through one end of the sampling end to be located in the outer needle assembly, the inner sampling needle head is close to the puncture end, and the auxiliary sampling unit is communicated with the inner sides of the transmission needle core and the inner sampling needle head.
Preferably, the inner sampling needle head comprises a cutting needle core and a thin-wall inner needle, the thin-wall inner needle is sleeved on the outer side of the cutting needle core, one end of the cutting needle core is coaxially and fixedly connected with one end of the transmission needle core, which is far away from the fixed shell, the other end of the cutting needle core is fixedly connected with a cutting blade, the cutting blade is close to the puncturing end, a thread groove is formed in the side wall of the cutting needle core, the cutting needle core passes through the thread groove and is in a hollow sheet thread-shaped structure, the cutting blade is positioned at one end of the thread groove, which is far away from the transmission needle core, and one end of the thin-wall inner needle, which is far away from the cutting blade, is coaxially and fixedly connected with the cutting needle core, and the wall thickness of the thin-wall inner needle is smaller than that of the transmission needle core.
Preferably, the outer needle assembly comprises a threaded end, a first outer needle, a second outer needle and a third outer needle which are fixedly connected with each other coaxially in sequence, one end of the threaded end, which is close to the sampling end, is in threaded connection with the fixed shell, the third outer needle is sleeved on the outer side of the cutting needle core, the wall thickness of the third outer needle is smaller than that of the second outer needle, and the auxiliary sampling unit is communicated with the inner side of the second outer needle through the first outer needle.
Preferably, the driving unit comprises a motor fixedly connected in the first cavity, a rotating shaft of the motor is coaxially fixedly connected with a threaded rod, a transmission support assembly is sleeved on the outer side of the threaded rod in a threaded mode, the transmission support assembly is slidably connected in the first cavity along the sampling direction, a gap is formed between one end of the transmission support assembly, which is far away from the motor, and one end of the threaded rod, which is far away from the transmission needle core, passes through the transmission support assembly and stretches into the threaded rod, the transmission support assembly is in transmission connection with the sliding rod assembly and the transmission needle core, and the threaded rod and the transmission support assembly drive the transmission needle core to stretch and sample through the sliding rod assembly.
Preferably, the slide bar assembly includes with the coaxial heart fixed connection's of transmission needle core axle core, the threaded rod is kept away from one end cover of motor is established the axle core passes the one end outside of transmission support assembly, the second spout has been seted up to the internal symmetry of threaded rod, the second spout sets up along the sample direction, the outside symmetry fixedly connected with otic placode of axle core, two sets of otic placode corresponds sliding connection respectively in two sets of in the second spout, the transmission needle core is close to the one end rotation of axle core is connected on the transmission support assembly, the transmission support assembly is kept away from one end of motor with the butt has the spring between the one end that is close to in the fixed casing the sampling end, the spring cover is established the outside of transmission needle core.
Preferably, the transmission support assembly comprises a threaded sleeve arranged on the outer side of the threaded rod in a threaded sleeved mode, a fixed connecting rod is symmetrically and fixedly connected to the edge of the threaded sleeve, two groups of fixed connecting rods are away from the same end of the motor and fixedly connected with the threaded rod, a gap is formed between the fixed connecting rods, a fixed ring is fixedly sleeved on the outer side of one end of the transmission needle core, two groups of fixed connecting rods are close to the same end of the transmission needle core, a threaded end cover is sleeved on the outer side of the same end of the transmission needle core in a threaded mode, the transmission needle core penetrates through the center of the threaded end cover, the fixed ring is located between the inner side of the threaded end cover and the two groups of fixed connecting rods, a plurality of balls are respectively matched between the fixed ring and the two groups of fixed connecting rods in a rolling mode, and the springs are abutted to the threaded end cover and one end of the fixed shell, which is close to the sampling end.
Preferably, two groups of the deviating sides of the fixed connecting rods are respectively vertically and fixedly connected with an upper sliding block and a lower sliding block, the upper sliding blocks are close to the motor, a fixed plate is symmetrically and fixedly connected in the first cavity, first sliding grooves are respectively formed in the opposite sides of the two groups of the fixed plates, and all the upper sliding blocks and the lower sliding blocks are slidably connected in the two groups of the first sliding grooves along the sampling direction.
Preferably, the puncture depth detection unit comprises a display screen and a distance sensor, wherein the display screen is fixedly connected to the outer side of one end of the fixed shell, which is far away from the sampling end, the distance sensor is fixedly connected to the first cavity, and the detection end of the distance sensor is correspondingly arranged with a group of upper sliding blocks.
The application has the following technical effects: under the guidance of CT, the puncture needle assembly is penetrated through the skin and extended into the tumor by holding the puncture handle; the puncture depth detection unit is mainly used for judging puncture depth data through displacement of the puncture needle assembly and is effectively combined with CT to achieve the purpose of accurate puncture; the driving unit is mainly used for driving the puncture needle assembly to puncture the tumor, and separating from the tumor after intercepting part of tumor samples; the auxiliary sampling unit has the main functions of assisting the driving unit, so that the sampling process is smoother and more stable, and meanwhile, the auxiliary driving unit can also enable the sample to be separated from the puncture needle assembly; in whole, the application can automatically intercept and release tumor samples, and can accurately grasp the puncture depth, so that the whole sampling process is smoother and more stable.
Drawings
In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings that are needed in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present application, and other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic view of a sampling apparatus according to the present application;
FIG. 2 is a schematic diagram of the internal structure of the sampling device according to the present application;
FIG. 3 is an enlarged schematic view of part A in FIG. 2;
FIG. 4 is an enlarged schematic view of part B of FIG. 2;
FIG. 5 is a schematic view of the cutting insert of the present application;
FIG. 6 is a schematic cross-sectional view of a threaded rod according to the present application;
wherein, 1, puncture the hand grip; 2. starting a switch; 3. a fixed housing; 4. a display screen; 5. a threaded end; 6. a negative pressure pipe; 7. a first outer needle; 8. a second outer needle; 9. a third outer needle; 10. a first cavity; 11. a motor; 12. a distance sensor; 13. a fixed disc; 14. a fixed sleeve; 15. an upper slider; 16. a threaded sleeve; 17. a lower slide block; 18. a fixed connecting rod; 19. a threaded rod; 20. a shaft core; 21. a threaded end cap; 22. a via hole; 23. a transmission needle core; 24. a first chute; 25. cutting the needle core; 26. ear plates; 27. a ball; 28. fixing the circular ring; 29. a thin-walled inner needle; 30. a cutting edge; 31. a thread groove; 32. a second chute; 33. a needle opening; 34. a fixing plate; 35. a second cavity; 36. a liquid injection pipe; 37. a three-way joint; 38. and (3) a spring.
Detailed Description
The following description of the embodiments of the present application will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present application, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the application without making any inventive effort, are intended to be within the scope of the application.
In order that the above-recited objects, features and advantages of the present application will become more readily apparent, a more particular description of the application will be rendered by reference to the appended drawings and appended detailed description.
Referring to fig. 1-6, the application provides a tumor sampling device convenient for separating tumors, which comprises a fixed shell 3, wherein a puncture handle 1 is fixedly connected to the side wall of the fixed shell 3, one end of the fixed shell 3, which is close to the puncture handle 1, is connected with a puncture depth detection unit, one end of the fixed shell 3, which is far away from the puncture depth detection unit, is provided with a sampling end, the sampling end is connected with a puncture needle assembly, one end of the puncture needle assembly, which is far away from the sampling end, is provided with a puncture end, one end of the puncture needle assembly, which is far away from the puncture end, passes through the sampling end and is positioned in the fixed shell 3, a first cavity 10 is formed in the fixed shell 3, a driving unit is arranged in the first cavity 10, the puncture needle assembly drives sampling through the driving unit, an auxiliary sampling unit is communicated in the puncture needle assembly, and the auxiliary sampling unit is used for assisting the driving unit in sampling and is also convenient for releasing samples.
Under the guidance of CT, the puncture needle assembly is penetrated through the skin and extended into the tumor by holding the puncture handle 1; the puncture depth detection unit is mainly used for judging puncture depth data through displacement of the puncture needle assembly and is effectively combined with CT to achieve the purpose of accurate puncture; the driving unit is mainly used for driving the puncture needle assembly to puncture the tumor, and separating from the tumor after intercepting part of tumor samples; the auxiliary sampling unit has the main functions of assisting the driving unit, so that the sampling process is smoother and more stable, and meanwhile, the auxiliary driving unit can also enable the sample to be separated from the puncture needle assembly; in whole, the application can automatically intercept and release tumor samples, and can accurately grasp the puncture depth, so that the whole sampling process is smoother and more stable.
Further optimizing scheme, the pjncture needle assembly includes outer needle subassembly and interior needle subassembly, and the outside of needle subassembly is established to outer needle subassembly cover, and outer needle subassembly is kept away from the one end of puncture end and is dismantled to be connected on the sampling end, and interior needle subassembly passes the sampling end and is located the one end and the output transmission of drive unit that the fixed casing 3 is connected, and supplementary sampling unit passes outer needle subassembly and interior needle subassembly internal communication.
Firstly, incision treatment is carried out on the skin surface close to the tumor, a puncture handle 1 is held by a hand to enable a puncture needle assembly to extend into the skin incision and reach the tumor surface, then an inner needle assembly is driven by a driving unit to move, so that the inner needle assembly is used for puncturing and sampling, and a tumor sample is conveniently released by the inner needle assembly through an auxiliary sampling unit.
Further optimizing scheme, interior needle subassembly is including fixed connection's slide bar assembly, transmission needle core 23 and interior sample syringe needle in proper order, and slide bar assembly is connected with the output transmission of drive unit, makes slide bar assembly pivoted move along the sample direction simultaneously, and the one end that transmission needle core 23 runs through the sample end is located outer needle subassembly, and interior sample syringe needle is close to the puncture end setting, and auxiliary sampling unit and transmission needle core 23, interior sample syringe needle inboard intercommunication.
The slide bar assembly is driven to rotate by starting the driving unit, the transmission needle core 23 and the inner sampling needle head are synchronously driven to rotate, and sampling is carried out by rotating and moving along the sampling direction.
Further optimizing scheme, interior sampling syringe needle includes cutting needle core 25 and thin wall inner needle 29, thin wall inner needle 29 cover is established in the outside of cutting needle core 25, the one end of cutting needle core 25 and the one end coaxial fixed connection that fixed casing 3 was kept away from to transmission needle core 23, the other end fixedly connected with cutting edge 30 of cutting needle core 25, cutting edge 30 is close to the puncture end, threaded groove 31 has been seted up on the lateral wall of cutting needle core 25, cutting needle core 25 forms hollow thin slice heliciform structure through threaded groove 31, cutting edge 30 is located the one end that threaded groove 31 kept away from transmission needle core 23, the one end coaxial fixed connection that cutting edge 30 was kept away from to thin wall inner needle 29 is on cutting needle core 25, the wall thickness of thin wall inner needle 29 is less than the wall thickness of transmission needle core 23.
When the driving unit drives the slide bar assembly, the cutting needle core 25 and the thin-wall inner needle 29 are synchronously driven to rotate and move along the sampling direction, the cutting needle core 25 is synchronously penetrated in a rotating state, tumors can be cut, and cut tumor blocks enter the inner cavity of the cutting needle core 25, in the penetrating process, the thin-wall inner needle 29 synchronously moves along with the cutting needle core 25, so that the cut tumor blocks are ensured to be stored in the cutting needle core 25, when the inner sampling needle head is conveniently pulled out, tissue fluid on the surface of the tumor blocks is prevented from polluting other tissues, and meanwhile, the integrity of tumor samples is ensured; the wall thickness of the thin-walled inner needle 29 being smaller than the wall thickness of the drive core 23 enables as much of the sample to be taken as possible from the inner cavity of the cutting core 25.
Further optimizing scheme, outer needle subassembly is including coaxial fixed connection's screw thread end 5, first outer needle 7, second outer needle 8 and third outer needle 9 in proper order, and the one end that screw thread end 5 is close to the sampling end is threaded connection with fixed casing 3, and the outside at cutting needle core 25 is established to the 9 cover of third outer needle, and the wall thickness of third outer needle 9 is less than the wall thickness of second outer needle 8, and auxiliary sampling unit passes through first outer needle 7 and the inboard intercommunication of second outer needle 8.
At the time of puncturing, the third outer needle 9 and the second outer needle 8 are sequentially introduced into the body from the skin incision, and the needle opening 33 of the third outer needle 9 first contacts the tumor surface.
Further optimizing scheme, the drive unit includes fixed connection at the motor 11 in first cavity 10, the rotation axis coaxial fixedly connected with threaded rod 19 of motor 11, threaded rod 19's outside thread bush is equipped with the transmission support assembly, transmission support assembly is along sample direction sliding connection in first cavity 10, be provided with the clearance between the one end that motor 11 was kept away from to the transmission support assembly and the one end of threaded rod 19, the one end that the transmission needle core 23 was kept away from to the slide bar assembly is passed the transmission support assembly and is still stretched into in the threaded rod 19, transmission support assembly is connected with slide bar assembly, transmission needle core 23 transmission, threaded rod 19 passes through the flexible sample of slide bar assembly drive transmission needle core 23 with the transmission support assembly.
When the motor 11 is started to rotate, the threaded rod 19 is driven to rotate, the transmission support assembly and the slide rod assembly are driven to slide along the sampling direction, when the transmission support assembly moves to one end of the threaded rod 19 far away from the motor 11, the transmission support assembly is separated from a thread section of the threaded rod 19, the transmission support assembly and the threaded rod 19 relatively rotate, and as the threaded rod 19 and the slide rod assembly continue to rotate, the transmission support assembly does not move along the sampling direction any more, and at the moment, the cutting edge 30 is driven to cut off a tumor block through the rotation of the slide rod assembly.
Further optimizing scheme, the slide bar assembly includes the axle core 20 with the coaxial heart fixed connection of transmission needle core 23, the one end cover that the motor 11 was kept away from to threaded rod 19 is established in the one end outside that axle core 20 passed the transmission support assembly, second spout 32 has been seted up to the symmetry in the threaded rod 19, second spout 32 sets up along the sample direction, the outside symmetry fixedly connected with otic placode 26 of axle core 20, two sets of otic placodes 26 correspond sliding connection respectively in two sets of second spouts 32, the one end that the transmission needle core 23 is close to axle core 20 rotates to be connected on the transmission support assembly, the butt has spring 38 in the one end that the motor 11 was kept away from to the transmission support assembly and the one end that is close to the sampling end in the fixed casing 3, spring 38 cover is established in the outside of transmission needle core 23.
In the initial state, the spring 38 is in a free state, when the motor 11 rotates to drive the threaded rod 19 and the shaft core 20 to rotate, the shaft core 20 slides in the axis direction in the threaded rod 19 and the two groups of lugs 26 slide in the second sliding groove 32 through the transmission bracket assembly, so that the cutting needle core 25 is driven to rotate and move in the sampling direction at the same time, and a rotary cutting effect is formed; when the transmission support assembly is separated from the thread section of the threaded rod 19, the transmission support assembly and the threaded rod 19 relatively rotate, the spring 38 is compressed, and the cutting needle core 25 rotates without continuous puncture, the cutting edge 30 cuts off the intercepted tumor mass; when the motor 11 is reversely started, the threaded rod 19 and the shaft core 20 are driven to reversely rotate, the transmission support assembly is in threaded connection with the threaded rod 19 again under the action of the resilience force of the spring 38, the cutting edge 30 also plays a role of bearing a tumor sample at the moment, the tumor sample is prevented from sliding off from the cutting needle core 25 in a rotating state, and the cut tumor block is further driven to be separated from a tumor.
Further optimizing scheme, the transmission support assembly includes the screw thread sleeve 16 of screw thread cover in the threaded rod 19 outside, the limit portion symmetry fixedly connected with fixed connecting rod 18 of screw thread sleeve 16, the same end fixed connection that motor 11 was kept away from to two sets of fixed connecting rods 18 and still be provided with the clearance between the threaded rod 19, the fixed cover in the one end outside that transmission needle core 23 is close to axle core 20 is equipped with fixed ring 28, the same end outside thread bush that two sets of fixed connecting rods 18 are close to transmission needle core 23 is equipped with screw thread end cover 21, transmission needle core 23 passes screw thread end cover 21 center, fixed ring 28 is located between screw thread end cover 21 inboard and two sets of fixed connecting rods 18, fixed ring 28 and screw thread end cover 21 inboard diapire, fixed ring 28 and two sets of fixed connecting rods 18 between the fixed ring 28 respectively rolling fit have a plurality of balls 27, spring 38 butt is between screw thread end cover 21 and the one end that is close to the sampling end in fixed casing 3.
The plurality of balls 27 can ensure that the transmission needle core 23 is smoother and more stable in the rotation and puncture process, and is also helpful for intercepting the integrity of tumor samples.
Further optimizing scheme, the deviating sides of two groups of fixed connecting rods 18 are respectively vertically fixedly connected with an upper sliding block 15 and a lower sliding block 17, the upper sliding block 15 is close to the motor 11, a fixed plate 34 is symmetrically and fixedly connected in the first cavity 10, first sliding grooves 24 are respectively formed in opposite sides of the two groups of fixed plates 34, and all the upper sliding blocks 15 and the lower sliding blocks 17 are slidably connected in the two groups of first sliding grooves 24 along the sampling direction.
Further optimizing scheme, puncture degree of depth detecting element includes display screen 4 and distance sensor 12, and display screen 4 fixed connection is in the one end outside that fixed casing 3 kept away from the sampling end, and distance sensor 12 fixed connection is in first cavity 10, and distance sensor 12's detection end corresponds the setting with a set of upper slider 15.
The distance of the upper sliding block 15 is monitored by the distance sensor 12, so that the puncture depth of the driving needle core 23 can be monitored in real time, the puncture accuracy is guaranteed together with CT, and the stability and smoothness of the whole puncture process are guaranteed.
According to a further optimization scheme, a fixed disc 13 is fixedly connected in the first cavity 10, a fixed sleeve 14 is fixedly penetrated through the center of the fixed disc 13, the fixed sleeve 14 is sleeved outside a rotating shaft of the motor 11, and a detection end of the distance sensor 12 penetrates through the fixed disc 13 and is correspondingly arranged with a group of upper sliding blocks 15.
Further optimizing scheme, second cavity 35 has been seted up between first outer needle 7 and the transmission needle core 23, a plurality of through-holes 22 have been seted up on the lateral wall of transmission needle core 23, fixed intercommunication has three way connection 37 on the lateral wall of first outer needle 7, three way connection 37 keeps away from the one end of first outer needle 7 and fixedly communicates respectively has negative pressure pipe 6 and annotates liquid pipe 36, through a plurality of through-holes 22 and negative pressure pipe 6 or annotate liquid pipe 36 intercommunication in the transmission needle core 23, the one end intercommunication that negative pressure pipe 6 kept away from three way connection 37 has negative pressure equipment or pump, the one end intercommunication that annotate liquid pipe 36 kept away from three way connection 37 has the normal saline syringe.
When the cutting edge 30 cuts off a tumor block, starting negative pressure equipment to adsorb a tumor sample on the cutting needle core 25, when the cutting needle core 25 needs to be pulled away from the incision, effectively avoiding the tumor sample from separating from the cutting needle core 25, when the cutting needle core 25 leaves a human body and stretches into preservation liquid, stopping negative pressure, starting an inflator pump, generating positive pressure in the transmission needle core 23, and pushing out the tumor sample; the cutting needle core 25 reaches the tumor surface, and before puncture, the normal saline injector can dilute tissue fluid on or near the tumor mass surface, so that the tissue fluid is prevented from affecting the interception amount of the tumor sample mass, and the puncture is facilitated.
In the description of the present application, it should be understood that the terms "longitudinal," "transverse," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like indicate or are based on the orientation or positional relationship shown in the drawings, merely to facilitate description of the present application, and do not indicate or imply that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus should not be construed as limiting the present application.
The above embodiments are only illustrative of the preferred embodiments of the present application and are not intended to limit the scope of the present application, and various modifications and improvements made by those skilled in the art to the technical solutions of the present application should fall within the protection scope defined by the claims of the present application without departing from the design spirit of the present application.
Claims (3)
1. A tumor sampling device for conveniently separating tumors, which is characterized in that: the device comprises a fixed shell (3), wherein a puncture handle (1) is fixedly connected to the side wall of the fixed shell (3), one end, close to the puncture handle (1), of the fixed shell (3) is connected with a puncture depth detection unit, one end, far away from the puncture depth detection unit, of the fixed shell (3) is set to be a sampling end, the sampling end is connected with a puncture needle assembly, one end, far away from the sampling end, of the puncture needle assembly is set to be a puncture end, one end, far away from the puncture end, of the puncture needle assembly penetrates through the sampling end and is positioned in the fixed shell (3), a first cavity (10) is formed in the fixed shell (3), a driving unit is arranged in the first cavity (10), the puncture needle assembly drives sampling through the driving unit, an auxiliary sampling unit is communicated in the puncture needle assembly and is used for assisting the driving unit in sampling and is also convenient for releasing samples; the puncture needle assembly comprises an outer needle assembly and an inner needle assembly, the outer needle assembly is sleeved on the outer side of the inner needle assembly, one end, far away from the puncture end, of the outer needle assembly is detachably connected to the sampling end, the inner needle assembly penetrates through the sampling end, one end, located in the fixed shell (3), of the inner needle assembly is in transmission connection with the output end of the driving unit, and the auxiliary sampling unit penetrates through the outer needle assembly and is communicated with the inner needle assembly; the inner needle assembly comprises a sliding rod assembly, a transmission needle core (23) and an inner sampling needle head which are sequentially and fixedly connected, the sliding rod assembly is in transmission connection with the output end of the driving unit, the sliding rod assembly rotates and moves along the sampling direction, one end of the transmission needle core (23) penetrating through the sampling end is positioned in the outer needle assembly, the inner sampling needle head is arranged close to the puncturing end, and the auxiliary sampling unit is communicated with the transmission needle core (23) and the inner side of the inner sampling needle head; the inner sampling needle comprises a cutting needle core (25) and a thin-wall inner needle (29), the thin-wall inner needle (29) is sleeved on the outer side of the cutting needle core (25), one end of the cutting needle core (25) is coaxially and fixedly connected with one end of the transmission needle core (23) far away from the fixed shell (3), the other end of the cutting needle core (25) is fixedly connected with a cutting blade (30), the cutting blade (30) is close to the puncturing end, a thread groove (31) is formed in the side wall of the cutting needle core (25), the cutting needle core (25) forms a hollow sheet thread-shaped structure through the thread groove (31), the cutting blade (30) is located at one end of the thread groove (31) far away from the transmission needle core (23), one end of the thin-wall inner needle (29) far away from the cutting blade (30) is coaxially and fixedly connected onto the cutting needle core (25), and the wall thickness of the thin-wall inner needle (29) is smaller than that of the transmission needle core (23); the outer needle assembly comprises a threaded end head (5), a first outer needle (7), a second outer needle (8) and a third outer needle (9) which are fixedly connected with each other in a coaxial mode in sequence, one end, close to the sampling end, of the threaded end head (5) is in threaded connection with the fixed shell (3), the third outer needle (9) is sleeved on the outer side of the cutting needle core (25), the wall thickness of the third outer needle (9) is smaller than that of the second outer needle (8), and the auxiliary sampling unit is communicated with the inner side of the second outer needle (8) through the first outer needle (7); the driving unit comprises a motor (11) fixedly connected in the first cavity (10), a rotating shaft of the motor (11) is coaxially and fixedly connected with a threaded rod (19), a transmission support assembly is sleeved on the outer side of the threaded rod (19), the transmission support assembly is slidably connected in the first cavity (10) along the sampling direction, a gap is formed between one end, away from the motor (11), of the transmission support assembly and one end of the threaded rod (19), one end, away from the transmission needle core (23), of the sliding rod assembly penetrates through the transmission support assembly and also stretches into the threaded rod (19), the transmission support assembly is in transmission connection with the sliding rod assembly and the transmission needle core (23), and the threaded rod (19) and the transmission support assembly drive the transmission needle core (23) to stretch and sample through the sliding rod assembly; the sliding rod assembly comprises a shaft core (20) fixedly connected with the coaxial center of the transmission needle core (23), one end, far away from the motor (11), of the threaded rod (19) is sleeved on the outer side of one end, far away from the motor (11), of the shaft core (20) penetrating through the transmission support assembly, second sliding grooves (32) are symmetrically formed in the threaded rod (19), the second sliding grooves (32) are formed in the sampling direction, ear plates (26) are symmetrically and fixedly connected to the outer side of the shaft core (20), two groups of ear plates (26) are correspondingly and slidingly connected in the two groups of second sliding grooves (32), one end, close to the shaft core (20), of the transmission needle core (23) is rotatably connected to the transmission support assembly, one end, far away from the motor (11), of the transmission support assembly is abutted against springs (38) between one end, close to the sampling end, in the fixed shell (3), of the springs (38) are sleeved on the outer side of the transmission needle core (23); the transmission bracket assembly comprises a threaded sleeve (16) which is sleeved on the outer side of the threaded rod (19), the edge of the threaded sleeve (16) is symmetrically and fixedly connected with a fixed connecting rod (18), two groups of fixed connecting rods (18) are fixedly connected with the same end of the motor (11) far away from the threaded rod (19), the gap is further formed between the fixed connecting rods and the threaded rod (19), a fixed circular ring (28) is fixedly sleeved on the outer side of one end of the transmission needle core (23) close to the shaft core (20), a threaded end cover (21) is sleeved on the outer side of the same end of the fixed connecting rod (18) close to the transmission needle core (23), the transmission needle core (23) penetrates through the center of the threaded end cover (21), the fixed circular ring (28) is positioned between the inner side of the threaded end cover (21) and the two groups of the fixed connecting rods (18), balls (27) are respectively matched between the fixed circular ring (28) and the inner side bottom wall of the threaded end cover (21) and the fixed connecting rods (18), and a plurality of balls (38) are respectively matched between the fixed circular ring (28) and the fixed circular ring and the fixed connecting rods (18), and the balls are abutted against one end of the fixed end cover (3) close to the threaded end cover (3).
Starting the motor (11) to rotate, driving the threaded rod (19) to rotate, driving the transmission support assembly and the sliding rod assembly to slide along the sampling direction, when the transmission support assembly moves to one end of the threaded rod (19) far away from the motor (11), the transmission support assembly is separated from a thread section of the threaded rod (19), the transmission support assembly and the threaded rod (19) rotate relatively, and the transmission support assembly does not move along the sampling direction any more along with the continuous rotation of the threaded rod (19) and the sliding rod assembly, and at the moment, the cutting edge (30) is driven to cut off a tumor block through the rotation of the sliding rod assembly.
2. The tumor sampling apparatus for facilitating tumor isolation according to claim 1, wherein: two sets of the deviating sides of fixed connecting rod (18) are respectively vertical fixedly connected with upper slide block (15) and lower slide block (17), upper slide block (15) are close to motor (11) setting, symmetry fixedly connected with fixed plate (34) in first cavity (10), two sets of first spout (24) have been seted up respectively to the opposite sides of fixed plate (34), all upper slide block (15) with lower slide block (17) are followed sample direction sliding connection in two sets of first spout (24).
3. The tumor sampling apparatus for facilitating tumor isolation according to claim 2, wherein: the puncture depth detection unit comprises a display screen (4) and a distance sensor (12), wherein the display screen (4) is fixedly connected to the outer side of one end, far away from the sampling end, of the fixed shell (3), the distance sensor (12) is fixedly connected to the first cavity (10), and the detection end of the distance sensor (12) is correspondingly arranged with a group of upper sliding blocks (15).
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| CN117442256B (en) * | 2023-12-26 | 2024-04-19 | 苏州华拓生物科技有限公司 | Tumor sampling device with cleaning function |
| CN117838205B (en) * | 2024-01-31 | 2024-09-24 | 中国人民解放军陆军军医大学第一附属医院 | Skin sampling device |
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