CN115475136A - Biological product for slowing body skin neutralization aging rate - Google Patents
Biological product for slowing body skin neutralization aging rate Download PDFInfo
- Publication number
- CN115475136A CN115475136A CN202211285429.0A CN202211285429A CN115475136A CN 115475136 A CN115475136 A CN 115475136A CN 202211285429 A CN202211285429 A CN 202211285429A CN 115475136 A CN115475136 A CN 115475136A
- Authority
- CN
- China
- Prior art keywords
- skin
- product
- neutralization
- body skin
- aging
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000006386 neutralization reaction Methods 0.000 title claims abstract description 20
- 230000032683 aging Effects 0.000 title claims abstract description 17
- 210000001541 thymus gland Anatomy 0.000 claims abstract description 20
- 210000000496 pancreas Anatomy 0.000 claims abstract description 19
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims abstract description 16
- 235000010413 sodium alginate Nutrition 0.000 claims abstract description 16
- 229940005550 sodium alginate Drugs 0.000 claims abstract description 16
- 239000000661 sodium alginate Substances 0.000 claims abstract description 16
- 108090000526 Papain Proteins 0.000 claims abstract description 13
- 239000004365 Protease Substances 0.000 claims abstract description 13
- 229940055729 papain Drugs 0.000 claims abstract description 13
- 235000019834 papain Nutrition 0.000 claims abstract description 13
- 239000002994 raw material Substances 0.000 claims abstract description 4
- 239000007788 liquid Substances 0.000 claims description 19
- 239000000203 mixture Substances 0.000 claims description 16
- 238000003756 stirring Methods 0.000 claims description 16
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 13
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 10
- KFSLWBXXFJQRDL-UHFFFAOYSA-N Peracetic acid Chemical compound CC(=O)OO KFSLWBXXFJQRDL-UHFFFAOYSA-N 0.000 claims description 10
- 238000010438 heat treatment Methods 0.000 claims description 9
- 238000002360 preparation method Methods 0.000 claims description 9
- 239000008213 purified water Substances 0.000 claims description 9
- 238000002791 soaking Methods 0.000 claims description 6
- CHHHXKFHOYLYRE-UHFFFAOYSA-M 2,4-Hexadienoic acid, potassium salt (1:1), (2E,4E)- Chemical compound [K+].CC=CC=CC([O-])=O CHHHXKFHOYLYRE-UHFFFAOYSA-M 0.000 claims description 5
- BCZXFFBUYPCTSJ-UHFFFAOYSA-L Calcium propionate Chemical compound [Ca+2].CCC([O-])=O.CCC([O-])=O BCZXFFBUYPCTSJ-UHFFFAOYSA-L 0.000 claims description 5
- 108010039918 Polylysine Proteins 0.000 claims description 5
- 235000010331 calcium propionate Nutrition 0.000 claims description 5
- 239000004330 calcium propionate Substances 0.000 claims description 5
- 239000000084 colloidal system Substances 0.000 claims description 5
- 210000002808 connective tissue Anatomy 0.000 claims description 5
- 238000002156 mixing Methods 0.000 claims description 5
- 229920000656 polylysine Polymers 0.000 claims description 5
- 235000010241 potassium sorbate Nutrition 0.000 claims description 5
- 239000004302 potassium sorbate Substances 0.000 claims description 5
- 229940069338 potassium sorbate Drugs 0.000 claims description 5
- 238000004537 pulping Methods 0.000 claims description 5
- JXKPEJDQGNYQSM-UHFFFAOYSA-M sodium propionate Chemical compound [Na+].CCC([O-])=O JXKPEJDQGNYQSM-UHFFFAOYSA-M 0.000 claims description 5
- 235000010334 sodium propionate Nutrition 0.000 claims description 5
- 239000004324 sodium propionate Substances 0.000 claims description 5
- 229960003212 sodium propionate Drugs 0.000 claims description 5
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 4
- 102000004895 Lipoproteins Human genes 0.000 claims description 3
- 108090001030 Lipoproteins Proteins 0.000 claims description 3
- 239000002158 endotoxin Substances 0.000 claims description 3
- 150000004676 glycans Chemical class 0.000 claims description 3
- 229920006008 lipopolysaccharide Polymers 0.000 claims description 3
- 229920001184 polypeptide Polymers 0.000 claims description 3
- 229920001282 polysaccharide Polymers 0.000 claims description 3
- 239000005017 polysaccharide Substances 0.000 claims description 3
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 3
- 102000007501 Thymosin Human genes 0.000 claims description 2
- 108010046075 Thymosin Proteins 0.000 claims description 2
- 235000013372 meat Nutrition 0.000 claims description 2
- 239000002674 ointment Substances 0.000 claims description 2
- LCJVIYPJPCBWKS-NXPQJCNCSA-N thymosin Chemical compound SC[C@@H](N)C(=O)N[C@H](CO)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CO)C(=O)N[C@H](CO)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@H]([C@H](C)O)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](C(C)C)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@H](CCC(O)=O)C(O)=O LCJVIYPJPCBWKS-NXPQJCNCSA-N 0.000 claims description 2
- 239000004382 Amylase Substances 0.000 claims 1
- 102000013142 Amylases Human genes 0.000 claims 1
- 108010065511 Amylases Proteins 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 102000019280 Pancreatic lipases Human genes 0.000 claims 1
- 108050006759 Pancreatic lipases Proteins 0.000 claims 1
- 102000004142 Trypsin Human genes 0.000 claims 1
- 108090000631 Trypsin Proteins 0.000 claims 1
- 235000019418 amylase Nutrition 0.000 claims 1
- 239000006071 cream Substances 0.000 claims 1
- 238000005138 cryopreservation Methods 0.000 claims 1
- 229940088598 enzyme Drugs 0.000 claims 1
- 229940116369 pancreatic lipase Drugs 0.000 claims 1
- 239000012588 trypsin Substances 0.000 claims 1
- 230000004060 metabolic process Effects 0.000 abstract description 15
- 230000004888 barrier function Effects 0.000 abstract description 2
- 239000000047 product Substances 0.000 abstract 2
- 239000012466 permeate Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 description 41
- 238000004140 cleaning Methods 0.000 description 6
- 238000000034 method Methods 0.000 description 5
- 230000008859 change Effects 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 238000000354 decomposition reaction Methods 0.000 description 3
- 230000008014 freezing Effects 0.000 description 3
- 238000007710 freezing Methods 0.000 description 3
- 239000012535 impurity Substances 0.000 description 3
- 230000003020 moisturizing effect Effects 0.000 description 3
- 210000000434 stratum corneum Anatomy 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 108010019160 Pancreatin Proteins 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 230000004071 biological effect Effects 0.000 description 2
- 239000002537 cosmetic Substances 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 238000004806 packaging method and process Methods 0.000 description 2
- 229940055695 pancreatin Drugs 0.000 description 2
- 210000004911 serous fluid Anatomy 0.000 description 2
- 239000000741 silica gel Substances 0.000 description 2
- 229910002027 silica gel Inorganic materials 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 210000004994 reproductive system Anatomy 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 230000009759 skin aging Effects 0.000 description 1
- 230000037075 skin appearance Effects 0.000 description 1
- 210000004927 skin cell Anatomy 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/733—Alginic acid; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Zoology (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a biological product for slowing down the neutralization aging rate of body skin, which is prepared from the following raw materials in parts by weight, 1000-4000 g of pancreas, 1000-4000 g of thymus, 10-300 g of papain and 10-100 g of sodium alginate; the invention makes animal pancreas, animal thymus, papain and sodium alginate into paste, freeze-dried powder or other forms. The biological product is independently used for body skin, can deeply clean three metabolism barrier garbage of the skin, permeate the skin, smooth the three metabolism, hydrate and moisten the skin, improve the skin lipoid metabolism level and slow down the rate of body skin neutralization and aging.
Description
Technical Field
The invention belongs to the field of human skin aging resistance, and particularly relates to a biological product for slowing down the rate of neutralization and aging of body skin.
Background
At present, some products such as cleaning products, skin care products, moisturizing products and the like exist in the cosmetic categories at home and abroad, but the products only play a role in beautifying the life of the skin and do not slow down the skin neutralization rate outside the body.
At present, the problems that the skin is seriously polluted repeatedly in the deep layer, three metabolism (gas metabolism, liquid metabolism and solid metabolism) passages of the skin are seriously blocked, the skin is neutralized in advance and the like cannot be solved for the skin outside the body at home and abroad, and the skin appearance damage mainly comes from three aspects, one is the influence of the reproductive system in the body; secondly, the influence of three major metabolism of the body skin; and the third is the influence of pollution or damage caused by the natural environment. All three factors directly contribute to accelerating the skin towards neutrality.
Although the skin cleaning products, the skin nursing products and the skin moisturizing products sold on the market at present and various medicines related to the skin have the functions, no product can be used for clearing the three skin metabolisms, ensuring the three skin metabolisms to be smooth and leading the skin to be transparent, and further the problem of slowing down the skin neutralization process is solved. Therefore, the development of a natural biological cosmetic product which can effectively clean the skin, promote three metabolism of the skin outside the body to be smooth and slow down the skin neutralization and aging rate is particularly necessary.
Disclosure of Invention
The biological product has the biological effects of deeply cleaning barrier garbage of three major metabolisms of the skin, enabling the skin to be permeable and smooth, enabling skin cells to be hydrated and moist, improving the skin lipoid metabolism level and slowing down the rate of neutralization of the natural aging of the body skin.
In order to achieve the purpose, the technical scheme of the invention is that the biological product for slowing down the neutralization aging rate of body skin is prepared from the following raw materials in parts by weight: 1000-4000 g of pancreas, 1000-4000 g of thymus, 10-300 g of papain and 10-150 g of sodium alginate.
The preparation method comprises the following steps:
firstly, crushing pancreas and thymus gland slices by a meat grinder, adding an ethanol solution of 3% peracetic acid by mass, and soaking for 10 hours at room temperature;
step two, adding purified water with the mass of 2.5 times of that of the mixture treated in the step one, and pulping by using a colloid mill; adding polylysine, potassium sorbate, calcium propionate and sodium propionate, stirring uniformly, slowly heating to 20-25 ℃, heating for 8 hours, and removing connective tissues by using an 80-mesh screen to obtain pancreas and thymus mixed feed liquid;
step three, adding papain into the mixture liquid obtained in the step two, and stirring and mixing uniformly to obtain a mixed liquid;
step four, preparing sodium alginate into a solution with the content of 1.5% by using purified water, adding the solution into the mixed feed liquid obtained in the step three, and uniformly stirring to obtain an ointment, namely the biological product for slowing down the body skin neutralization aging.
The invention has the following beneficial effects:
1. the present invention features that animal's pancreas and thymus are used as material and the product is prepared through soaking, grinding and low temperature preparation, and contains pancreatin, thymus peptide, polypeptide, polysaccharide, lipopolysaccharide, lipoprotein, etc.
2. The second characteristic of the invention is that the ingredients contained in the product have biodegradability.
3 the use observations of the inventive article show that: the pancreatin in the product can degrade the stratum corneum metabolized by the skin and die the cast-off cells, plays a biological role in cleaning and permeating the skin, and promotes smooth metabolism of the three parts of the skin; meanwhile, the thymosin, various polypeptides, polysaccharides, lipopolysaccharides and lipoprotein have the biological effects of moisturizing the skin, and the phenomenon of neutralization of the body skin is obviously slowed down after long-term use.
Detailed Description
The present invention is further illustrated by the following examples, which include, but are not limited to, the following examples.
A biological product for slowing the rate of neutralization and aging of body skin is prepared from the following raw materials in parts by weight: 1000-4000 g of pancreas, 1000-4000 g of thymus, 10-300 g of papain and 10-100 g of sodium alginate.
Example 1
A biological product for slowing the rate of neutralization aging of body skin comprises the following substances in parts by weight: 1000g of animal pancreas, 1000g of animal thymus, 35g of papain and 30g of sodium alginate. The preparation method comprises the following steps:
the method comprises the following steps: mixing animal pancreas and thymus slice, crushing, adding 3% ethanol solution of peroxyacetic acid, and soaking at low temperature for 8 hr;
step two: adding purified water with the mass of 2.5 times of that of the mixture treated in the first step into the mixture, and pulping by using a colloid mill;
step three: adding 48g (content: 0.6%) of polylysine, 48g (content: 0.6%) of potassium sorbate, 80g (content: 1%) of calcium propionate and 80g (content: 1%) of sodium propionate into the serous fluid obtained in the second step, uniformly stirring, slowly heating to 20-25 ℃, wherein the heating time is 8 hours, and then removing connective tissues by using a 80-mesh screen to obtain pancreas and thymus mixed fluid;
step four: adding papain into the mixture liquid obtained in the third step, and uniformly stirring to obtain a mixture liquid;
step five: preparing sodium alginate solution with 1.5% pure water; adding 1.5 percent of 2L sodium alginate solution into the mixture liquid obtained in the fourth step, and uniformly stirring to obtain paste;
step six: and D, directly subpackaging the paste obtained in the step five into paste products, or freezing at low temperature to obtain frozen products.
Example 2
A biological product for slowing the rate of neutralization aging of body skin comprises the following substances in parts by weight: 1500g of pancreas, 1000g of thymus, 40g of papain and 40g of sodium alginate; the preparation method comprises the following steps:
the method comprises the following steps: mixing pancreas and thymus gland sliced sheet, crushing, adding 3% ethanol solution of peroxyacetic acid, and soaking at low temperature for 10 hr;
step two: adding purified water with the mass of 3 times into the mixture treated in the first step, and pulping by using a colloid mill;
step three: adding 55g (content: 0.5%) of polylysine, 55g (content: 0.5%) of potassium sorbate, 55g (content: 0.5%) of calcium propionate and 55g (content: 0.5%) of sodium propionate into the slurry obtained in the second step, uniformly stirring, slowly heating to 20-25 ℃, wherein the heating time is 10h, and then removing connective tissues by using an 80-mesh screen to obtain a pancreas and thymus mixed feed liquid;
step four: adding papain into the mixture liquid obtained in the third step, and uniformly stirring to obtain a mixed liquid;
step five: preparing sodium alginate solution with the content of 1.5% by using purified water, adding 1.5% of 2.7L of sodium alginate solution into the mixture liquid obtained in the fourth step, and uniformly stirring to obtain product paste;
step six: and D, directly packaging the product paste obtained in the step five into paste products, or freezing the product paste at low temperature to obtain frozen products.
Example 3
A biological product for slowing the rate of neutralization aging of body skin comprises the following substances in parts by weight: 2000g of pancreas, 2500g of thymus, 100g of papain and 75g of sodium alginate; the preparation method comprises the following steps:
the method comprises the following steps: mixing pancreas and thymus gland sliced sheet, crushing, adding 3% ethanol solution of peroxyacetic acid, and soaking at low temperature for 10 hr;
step two: adding purified water with the mass of 2.5 times of that of the mixture treated in the first step into the mixture, and pulping by using a colloid mill;
step three: adding 128g (content: 0.8%) of polylysine, 128g (content: 0.8%) of potassium sorbate, 32g (content: 0.2%) of calcium propionate and 32g (content: 0.2%) of sodium propionate into the serous fluid obtained in the second step, uniformly stirring, slowly heating to 20-25 ℃, heating for 10 hours, and then removing connective tissues by using a 80-mesh screen to obtain a pancreas and thymus mixed fluid;
step four: adding papain into the mixture liquid obtained in the third step, and uniformly stirring to obtain a mixed liquid;
step five: preparing sodium alginate into a solution with the content of 1.5% by using purified water, adding a 5.0L sodium alginate solution with the content of 1.5% into the mixture liquid obtained in the fourth step, and uniformly stirring to obtain a product paste;
step six: and D, directly packaging the product paste obtained in the step five into paste products, or freezing the product paste at low temperature to obtain frozen products.
Example 4
The product pastes prepared in examples 1-3 were tested for the stratum corneum catabolism of skin, according to the test methods shown in table 1:
table 1: examples 1-3 skin cleaning test of preparations
| Categories | Example 1 | Example 2 | Example 3 |
| Amount of product put in | 1g | 1g | 1g |
| The sheet stratum corneum is more than or equal to 20 meshes | 0.1g | 0.1g | 0.1g |
| Constant volume | 100ml | 100ml | 100ml |
| Temperature of | 25℃ | 25℃ | 25℃ |
| Time of stirring | 15 minutes | 15 minutes | 15 minutes |
| Filtering with 100 mesh screen | The screen mesh is free of impurities | The screen mesh is free of impurities | The screen mesh is free of impurities |
| Conclusion | Complete decomposition | Complete decomposition | Complete decomposition |
Example 5
The product paste prepared in the examples 1-3 is subjected to a skin water metabolism influence test, and the test method adopts a comparison method: one hand and the small arm are cleaned by 3g of the product paste prepared in the examples 1 to 3 in a way that the product paste is mixed with a proper amount of water, the product paste is smeared and massaged for 8 to 10 minutes and then is washed clean by clear water, the cleaned and dried hand and the small arm and the uncleaned other hand and the small arm are respectively sleeved by two plastic sleeves, 2g of water-absorbing color-changing silica gel is respectively put into the sleeves, and the sleeves are sealed by sealing glue. The test conditions were controlled to be constant at room temperature of 30 ℃, the timing was started when the color-changing silica gel was placed, the color-changing time was accurately observed and recorded, and the results are shown in table 2. The interval of 12 months was again determined as described above (the subjects involved in the experiment used this product on average 2 times per week between 12 months).
Table 2: examples 1-3 skin cleaning test of preparations
Remarking: the measuring environment temperature is 30 ℃, the color change time is 5 average time values, the number of people in each age group is 5, the color change time 1 is the determined age, and the color change time 2 is the measuring result after the color change time 1 is separated by 12 months.
The above description is only an embodiment of the present invention with excellent effect and expression, and is not intended to limit the present invention, and it is obvious to those skilled in the art that various modifications and variations can be made in the present invention. Any modification, equivalent replacement or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (3)
1. A biological product for slowing the rate of neutralization and aging of body skin is characterized by comprising the following raw materials in parts by weight: 1000-4000 g of pancreas, 1000-4000 g of thymus, 10-300 g of papain and 10-100 g of sodium alginate;
the preparation method comprises the following steps:
firstly, crushing pancreas and thymus gland slices by a meat grinder, adding an ethanol solution of 3% peracetic acid by mass, and soaking for 10 hours at room temperature;
step two, adding purified water with the mass of 2.5 times of that of the mixture treated in the step one, and pulping by using a colloid mill; adding polylysine, potassium sorbate, calcium propionate and sodium propionate, stirring uniformly, slowly heating to 20-25 deg.C for 8 hr, and removing connective tissue with 80 mesh sieve to obtain mixed pancreas and thymus feed liquid;
step three, adding papain into the mixture liquid obtained in the step two, and stirring and mixing uniformly to obtain a mixed liquid;
step four, preparing a solution with the content of 1.5% by using purified water for sodium alginate, adding the solution into the mixed liquid obtained in the step three, and uniformly stirring to obtain an ointment, namely the biological product for slowing body skin neutralization and aging.
2. The biologic product for slowing the rate of aging by neutralization of body skin according to claim 1, wherein said biologic product comprises trypsin, pancreatic amylase, pancreatic lipase, thymosin, a plurality of biological enzymes, polypeptides, polysaccharides, lipopolysaccharides, lipoproteins.
3. The biologic product for slowing the rate of aging of body skin neutralization according to claim 1, wherein said biologic product is a cream cryopreservation product, a freeze-dried product, or other form of preparation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211285429.0A CN115475136A (en) | 2022-10-20 | 2022-10-20 | Biological product for slowing body skin neutralization aging rate |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211285429.0A CN115475136A (en) | 2022-10-20 | 2022-10-20 | Biological product for slowing body skin neutralization aging rate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115475136A true CN115475136A (en) | 2022-12-16 |
Family
ID=84396772
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211285429.0A Pending CN115475136A (en) | 2022-10-20 | 2022-10-20 | Biological product for slowing body skin neutralization aging rate |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN115475136A (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6366124A (en) * | 1986-09-08 | 1988-03-24 | Yamakawa Boeki Kk | Production of deproteinized thymus extract having metabolic activity |
| JPS63188698A (en) * | 1987-01-29 | 1988-08-04 | Ichimaru Pharcos Co Ltd | Cell growth promoting substance extracted from bovine thymus, extraction thereof and inactivation treatment of virus |
| CN107281093A (en) * | 2017-08-28 | 2017-10-24 | 王发欣 | The method and moisturiser of moisturiser are prepared by animal pancreas |
| CN112442497A (en) * | 2019-09-04 | 2021-03-05 | 四川德博尔制药有限公司 | Preparation method of pancreatin |
-
2022
- 2022-10-20 CN CN202211285429.0A patent/CN115475136A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6366124A (en) * | 1986-09-08 | 1988-03-24 | Yamakawa Boeki Kk | Production of deproteinized thymus extract having metabolic activity |
| JPS63188698A (en) * | 1987-01-29 | 1988-08-04 | Ichimaru Pharcos Co Ltd | Cell growth promoting substance extracted from bovine thymus, extraction thereof and inactivation treatment of virus |
| CN107281093A (en) * | 2017-08-28 | 2017-10-24 | 王发欣 | The method and moisturiser of moisturiser are prepared by animal pancreas |
| CN112442497A (en) * | 2019-09-04 | 2021-03-05 | 四川德博尔制药有限公司 | Preparation method of pancreatin |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102552099B (en) | Composite biological agent used for skin beautifying and restoring and preparing method | |
| CN110051587A (en) | A kind of preparation method and application of the anti-apolexis composition containing a variety of sodium hyaluronates | |
| CN111067816A (en) | Moisturizing and repairing mask containing active polypeptide and preparation method thereof | |
| CN107496287B (en) | Whole plant synthetic surfactant-free cleansing product | |
| KR102006708B1 (en) | Soap composition using wood-cultivated ginseng and soap comprising the same | |
| CN110448521A (en) | Stem Cell Activity factor facial mask sticking dressing and preparation method for skin repair | |
| CN105168106B (en) | One kind three spends whitening and softening skin facial mask liquid and preparation method thereof | |
| KR20150039263A (en) | Cosmetic composition containing fermented herb extracts and marine derived materials | |
| CN116003577A (en) | Recombinant collagen for skin soothing and repairing and application thereof | |
| KR20150120426A (en) | Cosmetic composition containing a brown alga extract, a yeast extract and ascorbic acid | |
| CN104940109A (en) | Natural marine facial mask based on shell and preparation method of natural marine facial mask | |
| CN103385803B (en) | Preparation method of bacterial cellulose compound fish collagen protein facial mask | |
| CN114869815B (en) | Anti-dandruff antibacterial shampoo and preparation method thereof | |
| CN108977488B (en) | Elastin for intensive skin repair and preparation method thereof | |
| CN113101256B (en) | Anti-aging repair nanoemulsion and application thereof | |
| CN110368347A (en) | Anti-ageing reparation double-layer bi-color essence of one kind and preparation method thereof | |
| CN111714399B (en) | Whitening, antibacterial and cutin-removing hand sanitizer and preparation method thereof | |
| CN115475136A (en) | Biological product for slowing body skin neutralization aging rate | |
| JP2814003B2 (en) | External preparation for skin | |
| CN107898679A (en) | A kind of water light moisturizing stoste and preparation method thereof | |
| CN107961183A (en) | A kind of toxin expelling anti-inflammatory facial mask | |
| CN113244140A (en) | Composition for regulating skin micro-ecological balance and application and preparation method thereof | |
| CN111494279A (en) | Cleaning cosmetic and preparation method thereof | |
| CN113599322A (en) | A shampoo formula containing Gleditsia sinensis saponin and its preparation method | |
| CN105816415A (en) | Anti-wrinkle moisturizing EGF facial mask and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20221216 |