CN114966072B

CN114966072B - Gynecological sample analyzer and gynecological sample analysis method

Info

Publication number: CN114966072B
Application number: CN202210919205.4A
Authority: CN
Inventors: 王法雄; 刘文杰; 林瀚; 刘武
Original assignee: Shenzhen Reetoo Biotechnology Co Ltd
Current assignee: Shenzhen Reetoo Biotechnology Co Ltd
Priority date: 2022-08-02
Filing date: 2022-08-02
Publication date: 2022-11-18
Anticipated expiration: 2042-08-02
Also published as: CN114966072A

Abstract

The application provides a gynaecology sample analysis appearance and gynaecology sample analysis method, gynaecology sample analysis appearance includes: the sample introduction device is used for providing sample liquid to be detected; the gynecological analysis device is used for detecting gynecological secretion of the sample liquid to be detected; the slide reading device comprises a slide making mechanism, a dyeing mechanism and a slide reading mechanism, wherein the slide making mechanism is used for obtaining a sample bearing piece; the dyeing mechanism is used for dyeing the sample bearing piece to obtain a target bearing piece; the film reading mechanism is used for carrying out image acquisition and analysis on the target bearing piece; control means for: controlling the sample introduction device to obtain detection information of the sample liquid to be detected, and selecting a detection mode according to the detection information; controlling the gynecological analysis device and/or the film reading device to execute a detection process matched with the detection mode according to the detection mode; and after the detection process is executed, obtaining a sample analysis result of the sample to be detected.

Description

Gynecological sample analyzer and gynecological sample analysis method

Technical Field

The application relates to the technical field of medical equipment, in particular to a gynecological sample analyzer and a gynecological sample analysis method.

Background

The female vaginal micro-ecosystem is one of the human body micro-ecosystem, and consists of microbial colonies in the vagina, an endocrine regulation system, a vaginal anatomical structure and a local immune system. At present, the detection of the vaginal micro-ecosystem mainly comprises morphological detection and functional detection, wherein the morphological detection mainly comprises morphological indexes such as flora concentration, diversity, dominant bacteria, pathogenic microorganisms and various scores; the functional detection is to determine the status of the microbial function through the functional detection, mainly to determine the activity of metabolites and enzymes of the vaginal microbes, and to supplement the metabolites and enzymes to comprehensively evaluate the vaginal microecological state. If the morphological and functional detection results are inconsistent, the morphological detection is currently used as the main reference index.

At present, utilize gynaecology's analysis appearance to gynecology's secretion sample's testing analysis comparatively single, can only carry out the microscopic examination and dry chemical analysis to gynaecology's secretion sample, if carry out morphological analysis, need carry out film-making and dyeing to gynaecology's secretion sample alone or by hand, this just leads to inefficiency, is unfavorable for realizing the automation to manual film-making easily causes the film-making quality unstable, influences the accuracy of testing result.

Disclosure of Invention

The main purpose of the application is to provide a gynecological sample analyzer and a gynecological sample analysis method, and aims to provide a gynecological sample analyzer which is high in detection efficiency, full-automatic and comprehensive in detection type.

In a first aspect, the present application provides a gynaecological sample analyzer comprising:

the sample feeding device is used for providing a sample to be tested and eluting the sample to be tested to form sample liquid to be tested, and comprises a first track for bearing and conveying the sample to be tested and the sample liquid to be tested;

the gynecological analysis device is used for detecting gynecological secretion of the sample liquid to be detected;

the slide reading device comprises a slide making mechanism, a dyeing mechanism and a slide reading mechanism, wherein the slide making mechanism is used for making a sample liquid to be detected to obtain a sample bearing member; the dyeing mechanism is used for dyeing the sample bearing piece to obtain a target bearing piece; the film reading mechanism is used for carrying out image acquisition and analysis on the target bearing piece; wherein, the first track is connected with the gynecological analysis device and the film reading device;

the control device is used for controlling the first track to convey the sample liquid to be detected to the gynecological analysis device and/or the film reading device so as to realize specific item detection, and the control device is also used for:

controlling the sample introduction device to identify and obtain detection information of the sample liquid to be detected, and selecting a detection mode of the sample liquid to be detected according to the detection information;

controlling the gynecological analysis device and/or the film reading device to execute a detection process matched with the detection mode on the sample liquid to be detected according to the detection mode;

and after the detection process is executed, obtaining a sample analysis result of the sample to be detected.

In a second aspect, the present application provides a gynaecological sample analyser comprising:

the sample introduction device is used for providing a sample to be detected and eluting the sample to be detected to form sample liquid to be detected, and comprises a first track for bearing and conveying the sample to be detected and the sample liquid to be detected;

the slide reading device comprises a slide making and dyeing mechanism and a slide reading mechanism, wherein the slide making and dyeing mechanism is used for executing at least one of slide making operation and dyeing operation on the sample liquid to be detected so as to obtain the target bearing piece; the film reading mechanism is used for carrying out image acquisition and analysis on the target bearing piece; wherein, the first track is connected with the gynecological analysis device and the film reading device;

and after the detection process is finished, obtaining a sample analysis result of the sample to be detected.

In a third aspect, the present application provides a gynecological sample analysis method applied to a gynecological sample analyzer, where the gynecological sample analyzer includes: the sample feeding device is used for providing a sample to be tested and eluting the sample to be tested to form sample liquid to be tested, and comprises a first track for bearing and conveying the sample to be tested and the sample liquid to be tested; the gynecological analysis device is used for detecting gynecological secretion of the sample liquid to be detected; the slide reading device comprises a slide making mechanism, a dyeing mechanism and a slide reading mechanism, wherein the slide making mechanism is used for making a sample liquid to be tested into a slide to obtain a sample bearing member; the dyeing mechanism is used for dyeing the sample bearing piece to obtain a target bearing piece; the film reading mechanism is used for carrying out image acquisition and analysis on the target bearing piece; the first track is connected with the gynecological analysis device and the film reading device; the sample analysis method comprises the following steps:

the first track is controlled to convey the sample liquid to be detected to the gynecological analysis device and/or the film reading device so as to realize specific project detection, and the method further comprises the following steps:

The application provides a gynaecology sample analysis appearance and gynaecology sample analysis method, wherein, gynaecology sample analysis appearance includes: the sample feeding device is used for providing a sample to be tested and eluting the sample to be tested to form sample liquid to be tested, and comprises a first track for bearing and conveying the sample to be tested and the sample liquid to be tested; the gynecological analysis device is used for detecting gynecological secretion of the sample liquid to be detected; the piece reading device is connected with the gynecological analysis device and the piece reading device through the first rail and comprises a piece making mechanism, a dyeing mechanism and a piece reading mechanism, and the piece making mechanism is used for making a sample liquid to be detected into a piece to obtain a sample bearing member; the dyeing mechanism is used for dyeing the sample bearing piece to obtain a target bearing piece; the film reading mechanism is used for carrying out image acquisition and analysis on the target bearing piece; the control device is used for controlling the first track to convey the sample liquid to be detected to the gynecological analysis device and/or the film reading device so as to realize specific item detection, and the control device is also used for: controlling a sample introduction device to identify and obtain detection information of the sample liquid to be detected, and selecting a detection mode of the sample liquid to be detected according to the detection information; controlling the gynecological analysis device and/or the film reading device to execute a detection process matched with the detection mode on the sample liquid to be detected according to the detection mode; and after the detection process is executed, obtaining a sample analysis result of the sample to be detected. The application provides a gynaecology sample analyzer, through setting up sampling device, gynaecology analytical equipment, read piece device and controlling means, according to the detection mode control gynaecology analytical equipment of the sample liquid that awaits measuring and/or read the piece device to the sample liquid that awaits measuring execution and the detection flow that detects the mode matching, can improve the detection efficiency to gynaecology secretion sample, and degree of automation is high, realize the multiple detection and analysis to gynaecology secretion sample, provide more comprehensive basis for the diagnosis of gynaecology disease.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings needed to be used in the description of the embodiments are briefly introduced below, and it is obvious that the drawings in the following description are some embodiments of the present application, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without creative efforts.

Fig. 1 is a schematic block diagram of a gynecological sample analyzer according to an embodiment of the present application;

fig. 2 is a schematic structural diagram of a gynecological sample analyzer according to an embodiment of the present application;

FIG. 3 is a schematic view of a first type of test card and an empty slide according to the present application;

FIG. 4 is a schematic diagram of a second type of test card according to the present application;

FIG. 5 is a schematic view of a turntable assembly to which the present application relates;

FIG. 6 is a block diagram of a gynecological sample analyzer according to another embodiment of the present application;

FIG. 7 is a block diagram of an analyzer for gynecological samples according to another embodiment of the present application;

FIG. 8 is a block diagram of an analyzer for gynecological samples according to another embodiment of the present application;

FIG. 9 is a block diagram of an analyzer for gynecological samples according to another embodiment of the present application;

FIG. 10 is a block diagram of a gynecological sample analyzer according to another embodiment of the present application;

FIG. 11 is a block diagram of an analyzer for gynecological samples according to another embodiment of the present application;

fig. 12 is a schematic structural diagram of a gynecological sample analyzer according to another embodiment of the present application;

fig. 13 is a schematic flow chart illustrating the steps of the gynecological sample analysis method according to the present application.

Icon: 100. a gynecological sample analyzer; 10. a sample introduction device; 20. a gynecological analysis device; 30. a film reading device; 31. a sheet making mechanism; 32. a dyeing mechanism; 33. a film reading mechanism; 34. a film-making and dyeing mechanism; 60. a control device; 601. a processor; 602. a memory; 70. a first type of test card; 80. a second type of test card; 701. a first detection zone; 7011. a microscopic examination area; 7012. a drying chemical zone; 802. a second detection zone; 803. a barcode region; 90. empty glass slides; 201. a turntable assembly; 2011. a load bearing position; 2012. and carrying the hollow area.

Detailed Description

The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are some, but not all, of the embodiments of the present application. All other embodiments obtained by a person of ordinary skill in the art based on the embodiments in the present application without making any creative effort belong to the protection scope of the present application.

In the description of the present application, unless expressly stated or limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly and include, for example, fixed and removable connections or integral connections; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in this application will be understood to be a specific case for those of ordinary skill in the art.

The gynecological secretion (also called vaginal secretion) is a liquid secreted by the female reproductive system, detection and analysis of a gynecological secretion sample is a routine detection item in clinical medicine, and the detection and analysis result of the gynecological secretion sample can provide a basis for diagnosis of gynecological diseases. At present, it is comparatively single to utilize gynecological analysis appearance to the testing analysis of gynaecology's secretion sample, if carry out morphological analysis, need alone or manual to gynaecology's secretion sample film-making and dyeing, this just leads to inefficiency, is unfavorable for realizing the automation to manual film-making easily causes the film-making quality unstability, influences the accuracy of testing result.

Therefore, the application provides a gynecological sample analyzer and a gynecological sample analysis method, and aims to provide the gynecological sample analyzer which is high in detection efficiency, full-automatic and comprehensive in detection type.

In the following, some embodiments of the present application will be described in detail with reference to the accompanying drawings, and features in the following examples and embodiments may be combined with each other without conflict.

Referring to fig. 1 and 2, fig. 1 and 2 show a gynecological sample analyzer 100 according to the present application. The gynecological sample analyzer 100 includes a sample introduction device 10, a gynecological analysis device 20, and a slide reading device 30.

The sample introduction device 10 is used for providing a sample to be detected and eluting the sample to be detected to form a sample liquid to be detected, and includes a first track for carrying and transporting the sample to be detected and the sample liquid to be detected.

In some embodiments, the sample injection device 10 further comprises an elution mechanism for eluting the sample to be tested to form a sample solution to be tested.

Illustratively, the first track controllably conveys the sample to be tested along a first direction, and a plurality of functional positions are defined along the traveling track, the functional positions comprise a dilution position and a stirring position, the first track is utilized to convey the same sample to be tested to the dilution position and the stirring position in sequence, and meanwhile, the plurality of samples to be tested can be continuously conveyed.

The elution mechanism can be integrated in the gynecological analysis device 20, and comprises a dilution component and a stirring component, wherein the dilution component and the stirring component are sequentially arranged on the side of the sample injection component along the first direction. The diluting component is used for adding a diluting liquid to the sample to be tested when the first track conveys the sample to be tested to the diluting position. The stirring assembly is used for stirring the sample to be tested added with the diluent to finish elution when the sample to be tested is conveyed to the stirring position by the first track.

The gynecological analysis device 20 is used for gynecological project detection of the sample liquid to be detected. The gynecological item detection related to the application comprises but is not limited to wet chemical detection (also called microscopic examination) and dry chemical detection for gynecological secretion, wherein the microscopic examination detection item mainly detects visible components (such as mold, hyphae, clue cells, trichomonas, epithelial cells, white blood cells, bacilli, cocci, small round epithelial cells, red blood cells and the like) in the gynecological secretion; the dry chemical detection mainly aims at the reaction structure of gynecological secretion, and comprises items such as neuraminidase (SNA), beta-N-acetylglucosaminidase (NAG), leukocyte esterase activity (LE), lactic acid, oxidase, proline aminopeptidase (PIP), pH value, hydrogen peroxide and the like.

The slide reading device 30 comprises a slide making mechanism 31, a dyeing mechanism 32 and a slide reading mechanism 33, wherein the slide making mechanism 31 is used for making a slide of a sample liquid to be measured to obtain a sample bearing member, the dyeing mechanism 32 is used for dyeing the sample bearing member to obtain a target bearing member, and the slide reading mechanism 33 is used for carrying out image acquisition and analysis on the target bearing member. Wherein, the first track connects the gynecological analysis device 20 and the radiograph reading device 30.

The control device 60 is in communication connection with the sample injection device 10, the gynecological analysis device 20 and the film reading device 30, so as to control the sample injection device 10, the gynecological analysis device 20 and the film reading device 30 to complete corresponding detection procedures for the sample to be detected according to different detection modes.

In some embodiments, control device 60 includes at least a processor 601, a memory 602, a communication interface (not shown), and an I/O interface (not shown). The processor 601, memory 602, communication interface, and I/O interface communicate over a bus. The Processor 601 may be a Central Processing Unit (CPU), and the Processor 601 may also be other general purpose Processor 601, a Digital Signal Processor 601 (DSP), an Application Specific Integrated Circuit (ASIC), a Field Programmable Gate Array (FPGA) or other Programmable logic device, discrete Gate or transistor logic device, discrete hardware component, etc. The general-purpose processor 601 may be a microprocessor 601 or the processor 601 may be any conventional processor 601 or the like.

The memory 602 stores therein various computer programs executed by the processor 601, such as an operating system and an application program, and data necessary for executing the computer programs. Data that is stored locally during analysis of a sample to be tested may be stored in the memory 602, if desired. The I/O interface includes, but is not limited to, a serial interface such as USB, IEEE1394, or RS-232C, a parallel interface such as SCSI, IDE, or IEEE1284, and an analog signal interface including a D/A converter and a converter. An input device is coupled to the I/O interface and may be used by a user to input data directly to the control device 60, including but not limited to a keyboard, mouse, touch screen, or control buttons. The display device can be connected with the control device 60 through the I/O interface for prompting relevant information. The communication interface may be any currently known communication protocol, and the communication interface communicates with the outside through a network, and the control device 60 may transmit data with any device connected through the network through the communication interface in a preset communication protocol.

In some embodiments, the control device 60 is configured to control the first track to transport the sample liquid to be tested to the gynecological analysis device 20 and/or the slide reading device 30, so as to implement the specific item detection, and the control device 60 is further configured to:

controlling the sample introduction device 10 to identify and obtain detection information of the sample liquid to be detected, and selecting a detection mode of the sample liquid to be detected according to the detection information;

controlling the gynecological analysis device 20 and/or the film reading device 30 to execute a detection process matched with the detection mode on the sample liquid to be detected according to the detection mode;

Illustratively, the sample introduction device 10 provides a sample to be tested, and elutes the sample to be tested to form a sample solution to be tested. After the sample introduction device 10 identifies and obtains the detection information of the sample liquid to be detected, the detection mode of the sample liquid to be detected is selected according to the detection information. Controlling the gynecological analysis device 20 to execute a detection process matched with the detection mode on the sample liquid to be detected according to the detection mode, and acquiring a sample analysis result of the sample to be detected after the detection process is executed; or, controlling the slide reading device 30 to execute a detection process matched with the detection mode on the sample liquid to be detected according to the detection mode, and obtaining a sample analysis result of the sample to be detected after the execution of the detection process is finished; or, the gynecological analysis device 20 and the slide reading device 30 are controlled to execute a detection process matched with the detection mode on the sample liquid to be detected according to the detection mode, and after the execution of the detection process is finished, a sample analysis result of the sample to be detected is obtained.

The application provides a gynaecology sample analysis appearance 100, through setting up sampling device 10, gynaecology analytical equipment 20, read piece device 30 and controlling means 60, according to the detection mode control gynaecology analytical equipment 20 of the sample liquid that awaits measuring and/or read piece device 30 to the sample liquid that awaits measuring execution and the detection flow that detects the mode matching, can improve the detection efficiency to gynaecology secretion sample, degree of automation is high, the realization is to the multiple detection and analysis of gynaecology secretion sample, provide more comprehensive basis for the diagnosis of gynaecology disease.

In some embodiments, the detection mode includes at least two of a first detection mode, a second detection mode, and a third detection mode;

when the gynecological sample analyzer 100 is in the first detection mode state, the control device 60 controls the first rail to convey the sample liquid to be detected to the gynecological analyzing device 20, and the gynecological analyzing device 20 executes a first detection process on the sample liquid to be detected, so as to obtain a first sample analysis result of the sample to be detected after the first detection process is executed;

when the gynecological sample analyzer 100 is in the second detection mode, the control device 60 controls the first rail to convey the sample liquid to be detected to the film reading device 30, and the film reading device 30 executes a second detection process on the sample liquid to be detected, so as to obtain a second sample analysis result of the sample to be detected after the second detection process is executed;

when the gynecological sample analyzer 100 is in the third detection mode, the control device 60 controls the first rail to convey the sample liquid to be detected to the gynecological analysis device 20 and the film reading device 30, and the gynecological analysis device 20 and the film reading device 30 execute a third detection process on the sample liquid to be detected, so as to obtain a third sample analysis result of the sample to be detected after the third detection process is executed.

Illustratively, when the gynecological sample analyzer 100 is in the third detection mode, the control device 60 controls the first rail to convey the sample liquid to be detected to the gynecological analysis device 20 and the slide reading device 30 in sequence, the gynecological analysis device 20 performs a first detection procedure on the sample liquid to be detected, and the slide reading device 30 performs a second detection procedure on the sample liquid to be detected, so as to obtain a third sample analysis result of the sample liquid to be detected after the first detection procedure and the second detection procedure.

In some embodiments, the first sample analysis result comprises a dry chemistry analysis result and a microscopy analysis result; and/or, the second sample analysis results comprise microecological morphological analysis results; and/or the third sample analysis results comprise dry chemistry analysis results, microscopic analysis results, and micro-ecological morphology analysis results.

In some embodiments, the dry chemistry analysis results include at least pH, hydrogen peroxide, leukocyte esterase, lactate, oxidase, sialidase detection, β -glucuronidase, acetylglucosaminidase, proline aminopeptidase, alkaline phosphatase, coagulase results; and/or the presence of a gas in the gas,

microscopic examination analysis results at least comprise cell cleanliness, white blood cell number, pus cell number, red blood cell number and clue cell detection results; and/or the presence of a gas in the atmosphere,

the micro-ecological morphology analysis result at least comprises the following steps: epithelial cells, flora density, lactobacillus proportion, flora diversity, other mixed bacteria proportion, mycoplasma-like corpuscles, chlamydia-like corpuscles, intracellular G-diplococcus, treponema pallidum, blastospores, hyphae, clue cells, trichomonas, white blood cells, red blood cells, campylobacter shapeformis, gram negative bacilli, gardnerella/bacteroides, cocci and the like.

In some embodiments, gynecological analysis device 20 includes a first sampling mechanism and scoring device 30 includes a second sampling mechanism.

When the gynecological sample analyzer 100 is in the third detection mode, the control device 60 is configured to:

controlling a first sampling mechanism to collect sample liquid to be detected; after the collection is completed and before the first sample analysis result is not obtained, controlling the first track to convey the sample liquid to be detected to the film reading device 30, and controlling the second sampling mechanism to collect the same sample liquid to be detected; or,

when the gynecological sample analyzer 100 is in the first detection mode, the control device 60 is configured to:

controlling a first sampling mechanism to collect sample liquid to be detected; after obtaining the first sample analysis result, the control device 60 determines whether the first track performs conveying of the sample liquid to be detected to the slide reading device 30 according to the sample analysis result; if yes, the first track is controlled to convey the sample liquid to be detected to the film reading device 30, and the second sampling mechanism is controlled to collect the same sample liquid to be detected.

For example, the second sampling mechanism is disposed in the film-making mechanism 31, and when the gynecological sample analyzer 100 is in the third detection mode, the first detection process and the second detection process need to be performed on the sample to be detected at one time. The control device 60 controls the first sampling mechanism to collect the sample liquid to be detected; after the collection is completed, the gynecological analysis device 20 executes a first detection process to perform dry chemical detection and microscopic examination on the sample liquid to be detected. Before the first sample analysis result is not obtained, the control device 60 controls the first track to convey the sample liquid to be detected to the slide making mechanism 31, and controls the second sampling mechanism to collect the same sample liquid to be detected, so that the slide reading device 30 executes the second detection process. After the gynecological analysis device 20 completes the first detection process and the slide reading device 30 completes the second detection process, the first sample analysis result and the second sample analysis result are obtained respectively.

Or, the gynecological sample analyzer 100 is in the first detection mode, and the control device 60 controls the first sampling mechanism to collect the sample liquid to be detected; after the acquisition is completed, the gynecological analysis device 20 executes a first detection procedure and obtains a first sample analysis result. If the first sample analysis result is abnormal, the user directly inputs an instruction to the control device 60 by using the input device, and the control device 60 controls the first track to convey the sample liquid to be detected to the slide making mechanism 31 according to the instruction, and controls the second sampling mechanism to collect the same sample liquid to be detected, so that the slide reading device 30 executes the second detection process to obtain a second sample analysis result.

In some embodiments, when the gynecological sample analyzer 100 is in the second detection mode state, the control device 60 is configured to:

controlling the first track to convey the sample liquid to be tested to the slide reading device 30;

the film-making mechanism 31 is controlled to identify and acquire the detection information of the sample liquid to be detected, and whether the second detection process is carried out on the sample liquid to be detected is judged according to the detection information;

if the second detection process is judged to be carried out on the sample liquid to be detected, controlling a second sampling mechanism to collect the sample liquid to be detected;

and if the sample liquid to be detected is judged not to be subjected to the second detection process, controlling the first track to convey another sample liquid to be detected.

In some embodiments, the sample feeding device 10 further includes a sample loading mechanism and a sample unloading mechanism, the first rail connects the sample loading mechanism and the sample unloading mechanism, and the first rail is exposed from the gynecological analysis device 20 and the slide reading device 30, the sample loading mechanism is configured to store and push a sample container containing a sample to be tested, wherein a first sampling position and a second sampling position are disposed on a path of the first rail;

when the gynecological sample analyzer 100 is in the first detection mode, the control device 60 controls the sample loading mechanism to sequentially transfer the plurality of sample containers to the first track, and controls the first track to transfer the sample containers to the first sampling position; after the first sampling mechanism collects the sample liquid to be detected in the sample container at the first sampling position, the first track is controlled to transfer the sample container to the sample unloading mechanism so as to recover the sample container which collects the sample liquid to be detected; and/or the presence of a gas in the gas,

when the gynecological sample analyzer 100 is in the second detection procedure, the control device 60 controls the sample placement mechanism to sequentially transfer the plurality of sample containers to the first track, and controls the first track to transfer the sample containers to the second sampling position; after the second sampling mechanism collects the sample liquid to be detected in the sample container at the second sampling position, the first track is controlled to transfer the sample container to the sample unloading mechanism so as to recover the sample container which collects the sample liquid to be detected; and/or the presence of a gas in the atmosphere,

when the gynecological sample analyzer 100 is in the third detection process, the control device 60 controls the sample loading mechanism to sequentially transfer the plurality of sample containers to the first track, and controls the first track to transfer the sample containers to the first sampling position; after the first sampling mechanism collects the sample liquid to be detected in the sample container at the first sampling position, the first track is controlled to transfer the sample container to the second sampling position, and after the second sampling mechanism collects the sample liquid to be detected in the sample container at the second sampling position, the first track is controlled to transfer the sample container to the sample unloading mechanism so as to recover the sample container which collects the sample liquid to be detected.

Illustratively, the sample loading mechanism is disposed at one end of the first track and the sample unloading mechanism is disposed at the other end of the first track. And the sample loading mechanism is arranged close to the gynecological analysis device 20, and the sample unloading mechanism is arranged close to the slide reading device 30. For example, referring to fig. 6, the sample unloading mechanism is disposed at the other end of the first rail and close to the slide making mechanism 31; alternatively, referring to fig. 7, the sample unloading mechanism is disposed at the other end of the first track and close to the staining mechanism 32; alternatively, referring to fig. 8, the sample unloading mechanism is disposed at the other end of the first rail and close to the slide reading mechanism 33; alternatively, referring to fig. 9, the sample loading mechanism is disposed at one end of the first rail and is disposed at a side of the gynecological analysis device 20 away from the slide-making mechanism 31, and the sample unloading mechanism is disposed at the other end of the first rail and is disposed at a side of the slide-reading mechanism 33 away from the slide-making mechanism 31.

In some embodiments, the first track is exposed to the gynecological analysis device 20 and the slide reader device 30.

Illustratively, the first track is exposed from the gynecological analysis device 20 and the radiographing device 30, and connects the gynecological analysis device 20 and the radiographing device 30. The first track is arranged on one side of the gynecological analysis device 20 and the slide reading device 30 and is close to the elution mechanism, the first sampling mechanism and the second sampling mechanism. The elution mechanism, the first sampling mechanism and the second sampling mechanism are arranged on one side of the first track, and the sample unloading mechanism and the sample loading mechanism are arranged on the other side of the first track.

In some embodiments, the gynecological sample analyzer 100 further comprises a card feeding device, wherein the card feeding device comprises a card storage mechanism for storing the detection card for carrying the sample liquid to be detected and a recovery mechanism for recovering the detected detection card, and the card storage mechanism is disposed adjacent to the gynecological analysis device 20 or located in the gynecological analysis device 20.

In some embodiments, the gynecological sample analyzer 100 further includes a second track for transporting the test card, the slide reading device 30 further includes a first transporting mechanism and a second transporting mechanism, the first transporting mechanism includes a first transporting unit disposed on the slide preparing mechanism 31 and a second transporting unit disposed on the staining mechanism 32, the second transporting mechanism includes a third transporting unit disposed on the slide reading mechanism 33, and the second track sequentially connects the first transporting unit, the second transporting unit and the third transporting unit.

Referring to fig. 3 and 4, in some embodiments, the detection card is the first type detection card 70, the first type detection card 70 includes a first detection area 701 for performing the first detection process on the first type detection card 70, the first conveying unit is used for feeding the carriers and conveying the carriers to the sheet making mechanism 31, and the second track is also used for conveying the carriers; or,

the detection card is a second type detection card 80, the second type detection card 80 comprises a first detection area 701 for carrying out the second type detection card 80 of the first detection flow and a second detection area 802 for carrying out the second detection flow, the gynecological analysis device 20 further comprises a card outlet unit for conveying the second type detection card, the second track is sequentially connected with the card outlet unit, the first conveying unit, the second conveying unit and the third conveying unit, and the first conveying unit is used for conveying the second type detection card 80 output by the card outlet unit to the film making mechanism 31.

For example, the first type of test card 70 can only perform the first test procedure of the gynecological analysis device 20, and if the second test procedure is to be performed on the sample liquid to be tested, the first transportation unit provided in the slide making mechanism 31 needs to provide a carrier, that is, an empty slide 90, and transport the carrier. The first conveying unit provides the empty slide 90, controls the second sampling mechanism to collect the sample liquid to be detected onto the empty slide 90, and controls the slide making mechanism 31, the staining mechanism 32 and the slide reading mechanism 33 to sequentially execute a second detection process on the slide carrying the sample liquid to be detected. After the slide reader 30 completes the second detection procedure, the second track is also used to transport the slide to the second recovery unit. The second type of test card 80 further includes a barcode area 803, and the barcode area 803 is identified to obtain corresponding information of the test card.

In some embodiments, the recovery mechanism includes a first recovery unit disposed in the gynecological analysis device 20 and a second recovery unit disposed in the radiographing device 30, wherein the first recovery unit is disposed in the gynecological analysis device 20, and the second recovery unit is disposed adjacent to the radiographing mechanism 33 or in the radiographing mechanism 33.

When the detection card executes the first detection mode for the first type detection card 70, the control device 60 controls the card bin mechanism to provide the first type detection card 70, and then controls the first sampling mechanism to transfer the collected sample liquid to be detected to the first type detection card 70; controlling the gynecological analysis device 20 to perform a first detection process on the sample liquid to be detected on the first type detection card 70; after the gynecological analysis device 20 completes the first detection process, the first type detection card 70 is conveyed to the first recovery unit for recovery; or,

when the detection card is the first type detection card 70 and executes the second detection mode, the control device 60 controls the first conveying unit to feed the bearing member, controls the second sampling mechanism to transfer the sample liquid to be detected to the bearing member, and controls the slide reading device 30 to perform a second detection process on the sample liquid to be detected on the bearing member; after the reading device 30 completes the second detection process, the bearing pieces are conveyed to the second recovery unit for recovery; or,

when the detection card executes the third detection mode for the first type detection card 80, the control device 60 controls the card bin mechanism to provide the first type detection card 70, and then controls the first sampling mechanism to transfer the collected sample liquid to be detected to the first type detection card 70; controlling the gynecological analysis device 20 to perform a first detection process on the sample liquid to be detected on the first type detection card 70; when the detection of the first detection process is finished or not finished, controlling the first conveying unit to feed the bearing piece, controlling the first track to transfer the sample container to the second sampling position, and controlling the second sampling mechanism to transfer the sample liquid to be detected to the bearing piece; controlling the slide reading device 30 to perform a second detection process on the sample liquid to be detected on the bearing piece; after the gynecological analysis device 20 completes the first detection process, the first type of detection card is conveyed to the first recovery unit for recovery, and after the slide reading device 30 completes the second detection process, the bearing piece is conveyed to the second recovery unit for recovery.

When the detection card executes the first detection mode for the second type detection card 80, the control device 60 controls the card bin mechanism to provide the second type detection card 80, and then controls the first sampling mechanism to transfer the collected sample liquid to be detected to the first detection area 701 of the second type detection card 80; controlling the gynecological analysis device 20 to perform a first detection process on the sample liquid to be detected on the second type detection card 80, and then conveying the second type detection card 80 to the first recovery unit for recovery; or,

when the second type detection card 80 executes the second detection mode, the control device 60 controls the card bin mechanism to provide the second detection card 80, and then controls the card output unit to convey the second type detection card 80 to the card reading device 30; meanwhile, the control device 60 controls the first track to transfer the sample container to the second sampling position and controls the second sampling mechanism to transfer the collected sample liquid to be detected to the second detection area 802, and the control device controls the film reading device 30 to perform a second detection process on the sample liquid to be detected in the second detection area 802; after the second detection process is completed, the film reading device 30 conveys the second type detection card 80 to a second recovery unit for recovery; or,

when the detection card executes the third detection mode for the second type detection card 80, the control device 60 controls the card bin mechanism to provide the second type detection card 80, and then controls the first sampling mechanism to transfer the collected sample liquid to be detected to the first detection area 701 of the second type detection card 80; controlling the gynecological analysis device 20 to perform a first detection process on the sample liquid to be detected on the first detection area 701 of the second type detection card 80; after the gynecological analysis device 20 completes the first detection process, the card output unit is controlled to convey the second type detection card 80 to the card reading device 30; controlling the second sampling mechanism to transfer the sample liquid to be detected to the second detection area 802 of the second type detection card 80, and controlling the slide reading device 30 to execute a second detection process on the sample liquid to be detected on the second type detection card 80; after the second detection process is completed, the sheet reading device 30 conveys the second type detection card 80 to the second recovery unit for recovery.

In some embodiments, controlling the slide reading device 30 to perform the second detection process on the sample liquid to be detected on the bearing member includes:

controlling the first conveying unit to convey the bearing piece bearing the sample liquid to be detected to the film making mechanism 31, and controlling the film making mechanism 31 to make a film on the bearing piece to obtain a sample bearing piece;

controlling the first conveying unit to convey the sample carriers to the second rail and controlling the second rail to convey the sample carriers to the second conveying unit;

controlling the second conveying unit to convey the sample bearing member to the dyeing mechanism 32, and controlling the dyeing mechanism 32 to dye the sample liquid to be detected on the sample bearing member to obtain a target bearing member;

controlling the second conveying unit to convey the target carrier to the second rail, and controlling the second rail to convey the target carrier to the third conveying unit;

and controlling the third conveying unit to convey the target bearing pieces to the film reading mechanism 33, and controlling the film reading mechanism 33 to perform image acquisition and analysis on the target bearing pieces.

In some embodiments, controlling the card-discharging unit to transport the second type of test card 80 to the sheet-reading device 30 includes:

the card-out unit is controlled to output the second type detection card 80 to the second track, and the second track is controlled to convey the second type detection card 80 to the first conveying unit.

The step of controlling the slide reading device 30 to execute the second detection process on the sample liquid to be detected on the second type of detection card 80 includes:

controlling the first conveying unit to convey the second type detection card 80 to the film making mechanism 31, and controlling the film making mechanism 31 to make a film on the second detection area 802 of the second type detection card 80;

controlling the first conveying unit to convey the second type of test cards 80 that have finished producing the sheets to the second track, and controlling the second track to convey the second type of test cards 80 to the second conveying unit;

controlling the second conveying unit to convey the second type of detection card 80 to the dyeing mechanism 32, and controlling the dyeing mechanism 32 to dye the sample liquid to be detected on the second type of detection card 80 to obtain a target bearing member;

and controlling the third conveying unit to convey the target bearing pieces to the film reading mechanism 33, and controlling the film reading mechanism 33 to acquire and analyze images of the target bearing pieces.

In some embodiments, the second track portion is embedded in slide viewing device 30; or, the second track is completely exposed outside the film reading device 30; or the second track part is embedded into the gynecological analysis device 20 and the film reading device 30; alternatively, the second track is entirely exposed to the gynecological analysis device 20 and the slide viewer 30.

In some embodiments, the card compartment mechanism includes at least two card compartments for storing the test cards, and the first test area 701 of the test cards includes any one of a quintuplet card, a sixplex card, a heptatuplet card, an octanext card, and a nonanext card; the control means 60 are also adapted to:

the type information of the first detection area 701 of the detection card is obtained, and the gynecological analysis device 20 is controlled to perform gynecological secretion detection on the sample liquid to be detected according to the type information.

Illustratively, where the first detection zone 701 is a six-up card, the dry chemistry zone 7012 of the first detection zone 701 includes six assay items of 6 reagent chromogenic paper, namely, neuraminidase (SNA), β -N-acetylglucosaminidase (NAG), leukocyte esterase activity (LE), proline aminopeptidase (PIP), PH, and hydrogen peroxide; when the first detection zone 701 is an eight-card reader, the drying chemical zone 7012 of the first detection zone 701 includes 8 reagent color papers, i.e., eight detection items including catalytic activities of neuraminidase (SNA), β -N-acetylglucosaminidase (NAG), leukocyte esterase activity (LE), proline aminopeptidase (PIP), PH, hydrogen peroxide, coagulase, and β -glucuronidase.

In some embodiments, the magazine mechanism further includes an identification component for capturing image information of the magazine or the test card, and the control device 60 obtains type information of the first test area 701 of the test card according to the image captured by the identification component.

In some embodiments, the gynecological analysis device 20 further comprises a first identification component, the slide making mechanism 31 further comprises a second identification component, the staining mechanism 32 further comprises a third identification component, the slide reading mechanism 33 further comprises a fourth identification component, the first identification component comprises a first code scanner and a second code scanner, the second identification component comprises a third code scanner, a fourth code scanner and a printing unit, the third identification component comprises a fifth code scanner, and the fourth identification component comprises a sixth code scanner; the first and third scanners are used for scanning barcodes on sample containers containing samples to be detected so as to identify information of the samples to be detected, the second scanner is used for identifying barcode areas 803 of the first type detection card 70 and the second type detection card 80 so as to identify information of the detection cards, the fourth scanner is used for identifying barcode areas 803 of the second type detection card 80, the printing unit is used for printing the information of the samples to be detected on the bearing piece, and the fifth and sixth scanners are used for identifying the information of the samples to be detected on the second type detection card 80 or the bearing piece.

In some embodiments, when the gynecological sample analyzer 100 is in the first detection mode, the control device 60 is configured to:

controlling the sample introduction device 10 to provide the sample liquid to be detected, controlling the first scanner to identify and acquiring detection information of the sample liquid to be detected; the card bin mechanism is controlled to output the detection card, and the second code scanner is controlled to identify the information of the detection card;

controlling the gynecological analysis device 20 to perform a first detection process on the sample liquid to be detected on the detection card; or,

when the gynecological analyzer is in the second detection mode, the control device 60 is configured to:

controlling the sample introduction device 10 to provide the sample liquid to be detected, controlling the first scanner to identify and acquiring detection information of the sample liquid to be detected;

controlling the first track to convey the sample liquid to be detected to the film reading device 30, controlling the third code scanner to identify and obtain the detection information of the sample liquid to be detected, and judging whether the information obtained by the first code scanner and the third code scanner is consistent;

controlling the second track to convey the second type of test card 80 or carrier to the slide reader 30;

if the second track is conveyed by the second type detection card 80, controlling the fourth code scanner to identify the information of the second type detection card 80; if the second rail is used for conveying the bearing piece, the printing unit is controlled to print the information acquired by the first code scanner on the bearing piece;

controlling the fifth code scanner and the sixth code scanner to identify and acquire the information of the second type detection card 80 or the bearing member;

judging whether the detection information of the sample liquid to be detected corresponds to the information of the second type detection card 80 or the bearing piece or not according to the detection information of the sample liquid to be detected and the information of the second type detection card 80 or the bearing piece;

if the detection information of the sample liquid to be detected corresponds to the information of the second type detection card 80 or the information of the bearing piece, controlling the slide reading device 30 to perform a second detection process; or,

controlling the sample introduction device 10 to provide the sample liquid to be detected, controlling the first scanner to identify and obtain the detection information of the sample liquid to be detected; the card bin mechanism is controlled to output the detection card, and the second code scanner is controlled to identify the information of the detection card;

controlling the gynecological analysis device 20 to perform a first detection process on the sample liquid to be detected on the detection card;

when the gynecological analysis device 20 finishes or does not finish the first detection process, the first track is controlled to convey the sample liquid to be detected to the slide reading device 30, the third code scanner is controlled to identify and acquire the detection information of the sample liquid to be detected, and whether the information acquired by the first code scanner and the information acquired by the third code scanner are consistent or not is judged;

controlling the second track to convey the detection card or the bearing member to the film reading device 30;

controlling the fifth code scanner and the sixth code scanner to identify and acquire the information of the second type of detection card 80 or the bearing piece;

if the detection information of the sample liquid to be detected corresponds to the information of the second type of detection card 80 or the bearing member, the slide reading device 30 is controlled to perform a second detection process.

Referring to fig. 5, in some embodiments, the gynecological analysis device 20 further comprises a reaction mechanism and a detection mechanism, the reaction mechanism comprises a turntable assembly 201 for carrying a plurality of detection cards and an incubation assembly for heating the detection cards; the turntable assembly 201 is provided with a plurality of carrying positions 2011 for carrying the detection card, and the incubation assembly is provided with a plurality of incubation positions corresponding to the plurality of carrying positions 2011.

Exemplarily, the first sampling mechanism and the detection mechanism are respectively disposed on the outer peripheral side of the turntable assembly 201 along the circumferential direction of the turntable assembly 201, a plurality of carrying positions 2011 distributed along the circumferential direction are disposed on the turntable assembly 201, and each carrying position 2011 can carry one detection card (after the sample liquid to be detected is added to the detection card, that is, after the sample liquid to be detected is added to the detection card, it is equivalent to that the sample card position is used for carrying the sample liquid to be detected); the turntable assembly 201 controllably rotates around the axis thereof, the detection position is defined along the rotation track of the turntable assembly 201, the sample adding position and the detection position are sequentially arranged along the rotation track of the turntable assembly 201, the detection position corresponds to the detection mechanism, and the detection mechanism is used for carrying out gynecological item detection on the sample liquid to be detected. The incubation assembly is electrically connected to the control device 60 for heating the sample liquid to be measured on the turntable assembly 201 to keep the temperature of the sample liquid to be measured within a preset range. The incubation assembly is disposed opposite to the carousel assembly 201, below the carousel assembly 201, and a plurality of incubation positions are disposed corresponding to the plurality of loading positions 2011.

In some embodiments, the first detection zone 701 of the detection card includes a microscopy zone 7011 and a mummification zone 7012, and the areas of the loading position 2011 and the incubation position corresponding to the microscopy zone 7011 are hollow.

Illustratively, the incubation assembly is used to heat the sample liquid to be tested on the turntable assembly 201 so as to keep the temperature of the sample liquid to be tested within a preset range. The incubation assembly may be heated using a heat generating film and by thermal conduction to the test card on the turntable assembly 201. Since the sample liquid to be detected in the detection card microscopy area 7011 is heated to generate bubbles, which affects the microscopy photographing, the areas corresponding to the microscopy area 7011 on the bearing position 2011 and the incubation position are hollow, as shown in fig. 5, the hollow bearing area 2012 reduces the direct transmission of heat and the microscopy area 7011, and reduces the generation of bubbles. The detection mechanism comprises a microscopic examination component and a photographing component, correspondingly, the detection positions comprise a microscopic examination position and a photographing position, the microscopic examination component corresponds to the microscopic examination position, and the photographing component corresponds to the photographing position. The microscopic examination component and the photographing component are sequentially arranged on the outer peripheral side of the turntable component 201 along the circumferential direction of the turntable component 201. The gynecological item detection comprises a microscopic examination detection item and a dry chemical detection item, and accordingly, the first detection area 701 of the detection card carried and transported by the turntable assembly 201 comprises a dry chemical area 7012 and a microscopic examination area 7011. The microscopic examination component is used for detecting at least one item in microscopic examination detection items to obtain visible component information in the sample liquid to be detected; the photographing component is used for detecting at least one item in the dry chemical detection items so as to obtain the reaction structure information of the sample liquid to be detected.

Referring to fig. 10-12, in some embodiments, a gynecological sample analyzer 100 includes:

the sample feeding device 10 is used for providing a sample to be detected and eluting the sample to be detected to form sample liquid to be detected, and the sample feeding device 10 comprises a first track for bearing and conveying the sample to be detected and the sample liquid to be detected;

the gynecological analysis device 20 is used for detecting gynecological secretion of the sample liquid to be detected;

the slide reading device 30, the slide reading device 30 includes a slide-making and staining mechanism 34 and a slide-reading mechanism 33, the slide-making and staining mechanism 34 is used for executing at least one of slide-making operation and staining operation on the sample liquid to be tested to obtain the target bearing member; the film reading mechanism 33 is used for carrying out image acquisition and analysis on the target bearing piece; wherein, the first track is connected with the gynecological analysis device 20 and the film reading device 30;

the control device 60 is used for controlling the first track to convey the sample liquid to be tested to the gynecological analysis device 20 and/or the slide reading device 30 so as to realize the detection of specific items, and the control device 60 is further used for:

controlling the first conveying unit to convey the bearing piece bearing the sample liquid to be detected to the slide-making and dyeing mechanism 34, and controlling the slide-making and dyeing mechanism 34 to sequentially perform slide-making operation and dyeing operation on the sample liquid to be detected on the bearing piece to obtain a target bearing piece;

In some embodiments, controlling the slide reading device 30 to perform the second detection process on the sample liquid to be detected on the second type of detection card 80 includes:

controlling the first conveying unit to convey the second type detection card 80 to the slide-making and dyeing mechanism 34, and controlling the slide-making and dyeing mechanism 34 to sequentially perform slide-making operation and dyeing operation on the sample liquid to be detected on the second detection area 802 of the detection card 80 to obtain a target bearing member;

Referring to fig. 13, fig. 13 is a flowchart illustrating steps of a method for analyzing a gynecological sample according to an embodiment of the present application, wherein the method is applied to the gynecological sample analyzer 100. The gynecological sample analysis method comprises the steps of controlling a first rail to convey a sample liquid to be detected to a gynecological analysis device and/or a film reading device so as to realize specific project detection, and specifically comprises the following steps:

s10: controlling the sample introduction device to identify and obtain detection information of the sample liquid to be detected, and selecting a detection mode of the sample liquid to be detected according to the detection information;

s11: controlling the gynecological analysis device and/or the film reading device to execute a detection process matched with the detection mode on the sample liquid to be detected according to the detection mode;

s12: and after the detection process is finished, obtaining a sample analysis result of the sample to be detected.

when the gynecological sample analyzer is in a first detection mode state, the control device controls the first rail to convey the sample liquid to be detected to the gynecological analysis device, and the gynecological analysis device executes a first detection process on the sample liquid to be detected so as to obtain a first sample analysis result of the sample to be detected after the first detection process is executed;

when the gynecological sample analyzer is in a second detection mode, the control device controls the first rail to convey the sample liquid to be detected to the film reading device, the film reading device executes a second detection flow on the sample liquid to be detected, and a second sample analysis result of the sample to be detected is obtained after the second detection flow is executed;

when the gynecological sample analyzer is in the third detection mode, the control device controls the first rail to convey the sample liquid to be detected to the gynecological analysis device and the film reading device respectively, the gynecological analysis device and the film reading device execute a third detection process on the sample liquid to be detected, and a third sample analysis result of the sample to be detected is obtained after the third detection process is executed.

Referring to fig. 7, in some embodiments, when the test card is a first type test card, the method for analyzing gynecological samples includes:

if the detection mode is the first detection mode, the gynecological sample analysis method comprises the following steps:

the sample loading mechanism is controlled to feed a sample to be detected to the first track, the first identification component is controlled to identify and acquire detection information of the sample to be detected as a first detection mode, and the card bin mechanism is controlled to push a first type of detection card;

after the detection information of the sample to be detected is acquired as a first detection mode, controlling an elution mechanism to prepare the sample to be detected into sample liquid to be detected;

controlling a first sampling mechanism to sample the sample liquid to be detected to a first type detection card, and controlling a gynecological analysis device to perform gynecological item detection;

and after the gynecological item detection is finished, the first type detection card is moved to a first recovery unit for recovery, and a first sample analysis result is obtained.

If the detection mode is the second detection mode, the gynecological sample analysis method comprises the following steps:

controlling the sample loading mechanism to feed the sample to be detected to the first track, and controlling the sample feeding device to identify and acquire the detection information of the sample to be detected as a second detection mode;

after the detection information of the sample to be detected is acquired as a second detection mode, controlling an elution mechanism to prepare the sample to be detected into sample liquid to be detected;

the first track is controlled to convey the sample liquid to be detected to the slide making mechanism, the second identification component is controlled to identify and obtain detection information of the sample to be detected, and meanwhile the first conveying unit is controlled to push the empty slide;

controlling a second sampling mechanism to sample the sample liquid to be detected to an empty slide, and controlling a slide reading device to perform a second detection flow;

and after the second detection process is finished, controlling the second track to move the empty slide to the second recovery unit for recovery, and obtaining a second sample analysis result.

If the detection mode is the third detection mode, the gynecological sample analysis method comprises the following steps:

controlling the sample loading mechanism to feed the sample to be detected to the first track, controlling the sample feeding device to identify and obtain detection information of the sample to be detected as a third detection mode, and simultaneously controlling the card bin mechanism to push the first type of detection card;

after the detection information of the sample to be detected is acquired as a third detection mode, controlling an elution mechanism to prepare the sample to be detected into sample liquid to be detected;

after the gynecological item detection is finished, the first type detection card is moved to a first recovery unit for recovery;

controlling a second sampling mechanism to sample the sample liquid to be detected to an empty slide, and controlling a slide reading device to perform a second detection process;

and after the second detection process is finished, controlling the second track to move the empty slide to the second recovery unit for recovery, and obtaining a third sample analysis result.

Referring to fig. 8, in some embodiments, when the test card is a second type test card, the method for analyzing gynecological samples includes:

controlling the sample loading mechanism to feed the sample to be detected to the first track, controlling the sample feeding device to identify and acquire detection information of the sample to be detected as a first detection mode, and simultaneously controlling the card bin mechanism to push a second type of detection card;

controlling the first sampling mechanism to sample the sample liquid to be detected to a second type detection card, and controlling the gynecological analysis device to perform a first detection process;

and after the gynecological item detection is finished, the second type detection card is moved to the first recovery unit for recovery, and a first sample analysis result is obtained.

controlling the sample loading mechanism to feed the sample to be detected to the first track, controlling the sample feeding device to identify and acquire detection information of the sample to be detected as a second detection mode, and simultaneously controlling the card bin mechanism to push a second type of detection card;

controlling a second sampling mechanism to sample the sample liquid to be detected to a second detection area of a second type of detection card, and controlling a film reading device to perform a second detection process;

and after the second detection process is finished, controlling the second track to move the second type of detection card to a second recovery unit for recovery, and obtaining a second sample analysis result.

controlling the sample loading mechanism to feed the sample to be detected to the first track, controlling the sample feeding device to identify and acquire detection information of the sample to be detected as a third detection mode, and simultaneously controlling the card bin mechanism to push a second type of detection card;

controlling the first sampling mechanism to sample the sample liquid to be detected to a second type detection card, and controlling the gynecological analysis device to perform gynecological project detection;

after the gynecological item detection is finished, controlling the second track to move the second type of detection card to the film making mechanism;

controlling the first track to convey the sample liquid to be detected to the film-making mechanism, controlling the second identification component to identify and obtain the detection information of the sample to be detected, and controlling the second identification component to identify the detection information of the second type detection card;

judging whether the detection information of the second type detection card corresponds to the detection information of the sample liquid to be detected;

if the detection information of the second type of detection card corresponds to the detection information of the sample liquid to be detected, controlling a second sampling mechanism to sample the sample liquid to be detected to the second type of detection card, and controlling a film reading device to perform a second detection process;

and after the second detection process is finished, controlling the second track to move the second type detection card to a second recovery unit for recovery, and obtaining a third sample analysis result.

In some embodiments, whether the detection information of the second type of detection card corresponds to the detection information of the sample liquid to be detected is judged, if the detection information of the second type of detection card does not correspond to the detection information of the sample liquid to be detected, a repair instruction is obtained, and the first track is controlled to re-sample the sample liquid to be detected according to the repair instruction.

Illustratively, if the detection information of the second type of detection card does not correspond to the detection information of the sample liquid to be detected, the control device displays an error, the user can generate a repair instruction by selecting repair, and the control device moves the sample liquid to be detected to the sample unloading mechanism according to the repair instruction. And the user puts the sample liquid to be detected moved to the sample unloading mechanism into the sample loading mechanism again for sample introduction and detection.

It is to be understood that the terminology used in the description of the present application herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the application. As used in this specification and the appended claims, the singular forms "a", "an", and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise.

It should also be understood that the term "and/or" as used in this specification and the appended claims refers to and includes any and all possible combinations of one or more of the associated listed items. It should be noted that, in this document, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or system that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or system. Without further limitation, an element defined by the phrases "comprising one of 8230; \8230;" 8230; "does not exclude the presence of additional like elements in a process, method, article, or system that comprises the element.

The above-mentioned serial numbers of the embodiments of the present application are merely for description and do not represent the merits of the embodiments. The above description is only for the specific embodiments of the present application, but the scope of the present application is not limited thereto, and any person skilled in the art can easily think of various equivalent modifications or substitutions within the technical scope of the present application, and these modifications or substitutions should be covered within the scope of the present application. Therefore, the protection scope of the present application shall be subject to the protection scope of the claims.

Claims

1. A gynecological sample analyzer, comprising:

the sample feeding device is used for providing a sample to be detected and eluting the sample to be detected to form sample liquid to be detected, and comprises a first track for bearing and conveying the sample to be detected and the sample liquid to be detected;

the slide reading device comprises a slide making mechanism, a dyeing mechanism and a slide reading mechanism, wherein the slide making mechanism is used for making the sample liquid to be detected to obtain a sample bearing member; the dyeing mechanism is used for dyeing the sample bearing piece to obtain a target bearing piece; the film reading mechanism is used for carrying out image acquisition and analysis on the target bearing piece; wherein the first track is connected with the gynecological analysis device and the film reading device;

controlling the sample feeding device to identify and obtain detection information of the sample liquid to be detected, and selecting a detection mode of the sample liquid to be detected according to the detection information;

after the detection process is executed, obtaining a sample analysis result of the sample to be detected;

the detection modes include at least two of a first detection mode, a second detection mode, and a third detection mode;

when the gynecological sample analyzer is in the first detection mode state, the control device controls the first rail to convey the sample liquid to be detected to the gynecological analysis device, and the gynecological analysis device executes a first detection process on the sample liquid to be detected so as to obtain a first sample analysis result of the sample to be detected after the first detection process is executed;

when the gynecological sample analyzer is in the second detection mode state, the control device controls the first rail to convey the sample liquid to be detected to the film reading device, and the film reading device executes a second detection process on the sample liquid to be detected so as to obtain a second sample analysis result of the sample to be detected after the second detection process is executed;

when the gynecological sample analyzer is in the third detection mode state, the control device controls the first rail to convey the sample liquid to be detected to the gynecological analysis device and the film reading device respectively, and the gynecological analysis device and the film reading device execute a third detection process on the sample liquid to be detected so as to obtain a third sample analysis result of the sample to be detected after the third detection process is executed;

the gynecological analysis device comprises a first sampling mechanism, and the film reading device comprises a second sampling mechanism;

when the gynecological sample analyzer is in the third detection mode state, the control device is used for:

controlling the first sampling mechanism to collect the sample liquid to be detected; after the collection is finished and before a sample analysis result is not obtained, controlling the first track to convey the sample liquid to be detected to the film reading device, and controlling the second sampling mechanism to collect the same sample liquid to be detected; or,

when the gynecological sample analyzer is in the first detection mode, the control device is configured to:

controlling the first sampling mechanism to collect the sample liquid to be detected; after the sample analysis result is obtained, the control device judges whether the first track carries out conveying of the sample liquid to be detected to the film reading device or not according to the sample analysis result; if so, controlling the first track to convey the sample liquid to be detected to the film reading device, and controlling the second sampling mechanism to collect the same sample liquid to be detected.

2. A gynaecological sample analyser according to claim 1, wherein when the gynaecological sample analyser is in the second detection mode state, the control means is configured to:

controlling the first track to convey the sample liquid to be detected to the slide reading device;

controlling the film-making mechanism to identify and acquire detection information of the sample liquid to be detected, and judging whether the second detection process is carried out on the sample liquid to be detected according to the detection information;

if the second detection process is carried out on the sample liquid to be detected, controlling the second sampling mechanism to collect the sample liquid to be detected;

and if the second detection process is not carried out on the sample liquid to be detected, controlling the first track to convey another sample liquid to be detected.

3. The gynecological sample analyzer of claim 1, wherein the sample injection device further comprises a sample loading mechanism and a sample unloading mechanism, the first rail is connected to the sample loading mechanism and the sample unloading mechanism and exposed from the gynecological analysis device and the slide reading device, the sample loading mechanism is used for storing and pushing a sample container containing the sample to be tested, and a first sampling position and a second sampling position are arranged on a path of the first rail;

when the gynecological sample analyzer is in the first detection mode state, the control device controls the sample loading mechanism to sequentially transfer the sample containers to the first rail, and controls the first rail to transfer the sample containers to the first sampling position; after the first sampling mechanism collects the sample liquid to be detected in the sample container at the first sampling position, controlling the first track to transfer the sample container to the sample unloading mechanism so as to recover the sample container which has collected the sample liquid to be detected; and/or the presence of a gas in the gas,

when the gynecological sample analyzer is in the second detection mode, the control device controls the sample loading mechanism to sequentially transfer the plurality of sample containers to the first track and controls the first track to transfer the sample containers to the second sampling position; after the second sampling mechanism collects the sample liquid to be detected in the sample container at the second sampling position, controlling the first track to transfer the sample container to the sample unloading mechanism so as to recover the sample container which has collected the sample liquid to be detected; and/or the presence of a gas in the gas,

when the gynecological sample analyzer is in the third detection mode, the control device controls the sample loading mechanism to sequentially transfer the plurality of sample containers to the first rail, and controls the first rail to transfer the sample containers to the first sampling position; after the first sampling mechanism collects the sample liquid to be detected in the sample container at the first sampling position, the first track is controlled to transfer the sample container to the second sampling position, and after the second sampling mechanism collects the sample liquid to be detected in the sample container at the second sampling position, the sample unloading mechanism collects the sample container of the sample liquid to be detected in a recycling mode.

4. The gynecological sample analyzer of claim 3, further comprising a card feeding device, wherein the card feeding device comprises a card storage mechanism and a recycling mechanism, the card storage mechanism is used for storing the detection card for carrying the sample solution to be detected, the recycling mechanism is used for recycling the detection card after detection, and the card storage mechanism is arranged adjacent to or in the gynecological analyzing device.

5. The gynecological sample analyzer of claim 4, further comprising a second track for conveying the detection card, wherein the slide reading device further comprises a first conveying mechanism and a second conveying mechanism, the first conveying mechanism comprises a first conveying unit arranged on the slide reading mechanism and a second conveying unit arranged on the staining mechanism, the second conveying mechanism comprises a third conveying unit arranged on the slide reading mechanism, and the second track is sequentially connected with the first conveying unit, the second conveying unit and the third conveying unit.

6. The gynecological sample analyzer of claim 5,

the detection card is a first type detection card, the first type detection card comprises a first detection area of the first type detection card for performing a first detection process, the first conveying unit is used for feeding a bearing piece and conveying the bearing piece to the film making mechanism, and the second track is also used for conveying the bearing piece; or,

the detection card is a second type detection card, and the second type detection card comprises a first detection area of the second type detection card for performing a first detection process and a second detection area for performing a second detection process; the gynecological analysis device is characterized in that the gynecological analysis device further comprises a card outlet unit for conveying the second type detection card, the second rail is sequentially connected with the card outlet unit, the first conveying unit, the second conveying unit and the third conveying unit, and the first conveying unit is used for conveying the second type detection card output by the card outlet unit to the film making mechanism.

7. The gynecological sample analyzer of claim 6, wherein the recovery mechanism comprises a first recovery unit disposed in the gynecological analyzer and a second recovery unit disposed in the radiographing device; the first recovery unit is arranged in the gynecological analysis device, and the second recovery unit is arranged adjacent to the film reading mechanism or in the film reading mechanism;

when the detection card executes a first detection mode for the first type of detection card, the control device controls the card bin mechanism to provide the first type of detection card and then controls the first sampling mechanism to transfer the collected sample liquid to be detected to the first type of detection card; controlling the gynecological analysis device to perform a first detection process on the sample liquid to be detected on the first type of detection card; after the gynecological analysis device finishes a first detection process, the first type of detection card is conveyed to the first recovery unit for recovery; or,

when the detection card is the first type detection card and executes a second detection mode, the control device controls the first conveying unit to feed a bearing piece, controls the second sampling mechanism to transfer the sample liquid to be detected to the bearing piece, and controls the slide reading device to perform a second detection flow on the sample liquid to be detected on the bearing piece; after the film reading device finishes the second detection process, the bearing piece is conveyed to the second recovery unit for recovery; or,

when the detection card executes a third detection mode for the first type detection card, the control device controls the card bin mechanism to provide the first type detection card and then controls the first sampling mechanism to transfer the sample liquid to be detected to the first type detection card; controlling the gynecological analysis device to perform a first detection process on the sample liquid to be detected on the first type of detection card; when the detection of the first detection process is finished or not finished, controlling the first conveying unit to feed a bearing piece, controlling the first track to transfer the sample container to the second sampling position, and controlling the second sampling mechanism to transfer the sample liquid to be detected to the bearing piece; controlling the slide reading device to perform a second detection process on the sample liquid to be detected on the bearing piece; after the gynecological analysis device finishes a first detection flow, the first type of detection card is conveyed to the first recovery unit for recovery, and after the film reading device finishes a second detection flow, the bearing piece is conveyed to the second recovery unit for recovery; or,

when the detection card executes a first detection mode for the second type detection card, the control device controls the card bin mechanism to provide the second type detection card, and then controls the first sampling mechanism to transfer the collected sample liquid to be detected to the first detection area of the second type detection card; controlling the gynecological analysis device to carry out a first detection process on the sample liquid to be detected on a second type of detection card, and then conveying the second type of detection card to the first recovery unit for recovery; or,

when the detection card is the second type detection card and executes a second detection mode, the control device controls the card bin mechanism to provide the second detection card and then controls the card outlet unit to convey the second type detection card to the card reader; meanwhile, the control device controls the first track to transfer the sample container to the second sampling position and controls the second sampling mechanism to transfer the collected sample liquid to be detected to the second detection area, and the control device controls the film reading device to perform a second detection process on the sample liquid to be detected in the second detection area; after the film reading device finishes a second detection flow, the second type of detection card is conveyed to the second recovery unit for recovery; or,

when the detection card executes a third detection mode for the second type of detection card, the control device controls the card bin mechanism to provide the second type of detection card, and then controls the first sampling mechanism to transfer the collected sample liquid to be detected to the first detection area of the second type of detection card; controlling the gynecological analysis device to perform a first detection process on the sample liquid to be detected on the first detection area of the second type detection card; after the gynecological analysis device finishes a first detection process, the gynecological analysis device controls the card outlet unit to convey the second type of detection card to the card reading device; controlling the second sampling mechanism to transfer the sample liquid to be detected to a second detection area of the second type of detection card, and controlling the slide reading device to execute a second detection flow on the sample liquid to be detected on the second type of detection card; and after the second detection flow is completed, the sheet reading device conveys the second detection card to the second recovery unit for recovery.

8. The gynecological sample analyzer of claim 7, wherein the controlling the slide reading device to perform the second detection process on the sample liquid to be detected on the bearing member comprises:

controlling the first conveying unit to convey the bearing piece bearing the sample liquid to be detected to the film making mechanism, and controlling the film making mechanism to make a film on the bearing piece to obtain a sample bearing piece;

controlling the first transport unit to transport the specimen carriers to the second track and controlling the second track to transport the specimen carriers to the second transport unit;

controlling the second conveying unit to convey the sample bearing piece to the dyeing mechanism, and controlling the dyeing mechanism to dye the sample liquid to be detected on the sample bearing piece to obtain a target bearing piece;

and controlling the third conveying unit to convey the target bearing piece to the film reading mechanism, and controlling the film reading mechanism to carry out image acquisition and analysis on the target bearing piece.

9. The gynecological sample analyzer of claim 7, wherein the controlling the card-discharging unit to deliver the second type of test card to the reading device comprises:

the card outlet unit is controlled to output the second type of detection card to the second track, and the second track is controlled to convey the second type of detection card to the first conveying unit;

the step of controlling the slide reading device to execute the second detection flow to the sample liquid to be detected on the second type of detection card comprises the following steps:

controlling the first conveying unit to convey the second type of detection card to the sheet making mechanism, and controlling the sheet making mechanism to make a sheet of the second detection area of the second type of detection card;

controlling the first conveying unit to convey the second type of detection cards which have finished the production to the second track, and controlling the second track to convey the second type of detection cards to the second conveying unit;

controlling the second conveying unit to convey the second type of detection card to the dyeing mechanism, and controlling the dyeing mechanism to dye the sample liquid to be detected on the second type of detection card to obtain a target bearing piece;

and controlling the third conveying unit to convey the target bearing piece to the piece reading mechanism, and controlling the piece reading mechanism to carry out image acquisition and analysis on the target bearing piece.

10. A gynaecological sample analyser according to claim 5, wherein the second track portion is embedded in the slide reader; or the second track is completely exposed out of the film reading device; or the second track part is embedded into the gynecological analysis device and the film reading device; or the second track is completely exposed out of the gynecological analysis device and the film reading device.

11. The gynecological sample analyzer of claim 6, wherein the cartridge mechanism comprises at least two cartridges for storing the test cards, and the first test area of the test card comprises any one of a five-joint card, a six-joint card, a seven-joint card, an eight-joint card and a nine-joint card; the control device is further configured to:

and acquiring the type information of the first detection area of the detection card, and controlling the gynecological analysis device to carry out gynecological secretion detection on the sample liquid to be detected according to the type information.

12. The gynecological sample analyzer of claim 11, wherein the cartridge mechanism further comprises an identification component for collecting image information of the cartridge or the test card, and the control device obtains the type information of the first test area of the test card according to the image collected by the identification component.

13. The gynecological sample analyzer of claim 6, wherein the gynecological analysis device further comprises a reaction mechanism and a detection mechanism, the reaction mechanism comprising a carousel assembly for carrying a plurality of the detection cards and an incubation assembly for heating the detection cards; wherein, the carousel subassembly sets up a plurality of bearing position that is used for bearing the weight of the detection card, and the incubation subassembly corresponds a plurality of bearing position sets up a plurality of incubation positions.

14. The gynecological sample analyzer of claim 13, wherein the first detection area of the detection card comprises a microscopic examination area and a dry chemistry area, and the areas corresponding to the microscopic examination area on the bearing position and the incubation position are hollow.

15. The gynecological sample analyzer of claim 6, wherein the gynecological analysis device further comprises a first identification module, the slide preparation mechanism further comprises a second identification module, the staining mechanism further comprises a third identification module, the reading mechanism further comprises a fourth identification module, the first identification module comprises a first code scanner and a second code scanner, the second identification module comprises a third code scanner, a fourth code scanner and a printing unit, the third identification module comprises a fifth code scanner, and the fourth identification module comprises a sixth code scanner; the first code scanner and the third code scanner are used for scanning a bar code on a sample container containing a sample to be detected so as to identify information of the sample to be detected, the second code scanner is used for identifying bar code areas of the first type detection card and the second type detection card so as to identify information of the detection cards, the fourth code scanner is used for identifying bar code areas of the second type detection card, the printing unit is used for printing the information of the sample to be detected on the bearing piece, and the fifth code scanner and the sixth code scanner are used for identifying the information of the second type detection card or the sample to be detected on the bearing piece.

16. A gynaecological sample analyser according to claim 15, wherein when the gynaecological sample analyser is in the first detection mode, the control means is configured to:

controlling the sample introduction device to provide sample liquid to be detected, and controlling the first scanning code to identify and acquire detection information of the sample liquid to be detected; the card bin mechanism is controlled to output the detection card, and the second code scanner is controlled to identify the information of the detection card;

controlling the gynecological analysis device to perform the first detection process on the sample liquid to be detected on the detection card; or,

when the gynecological analyzer is in a second detection mode, the control device is used for:

controlling the sample introduction device to provide sample liquid to be detected, and controlling the first scanner to identify and acquire detection information of the sample liquid to be detected;

controlling the first track to convey the sample liquid to be detected to the film reading device, controlling the third code scanner to identify and acquire detection information of the sample liquid to be detected, and judging whether the information acquired by the first code scanner and the information acquired by the third code scanner are consistent;

controlling the second track to convey the second type of detection card or the bearing piece to the film reading device;

if the second type of detection card is conveyed by the second track, controlling the fourth code scanner to identify the information of the second type of detection card; if the second rail is used for conveying the bearing piece, controlling the printing unit to print the information acquired by the first code scanner on the bearing piece;

controlling the fifth code scanner and the sixth code scanner to identify and acquire information of a second type of detection card or the bearing piece;

judging whether the detection information of the sample liquid to be detected corresponds to the information of the second type detection card or the bearing piece or not according to the detection information of the sample liquid to be detected and the information of the second type detection card or the bearing piece;

if the detection information of the sample liquid to be detected corresponds to the information of the second type detection card or the information of the bearing piece, controlling the slide reading device to perform a second detection flow; or,

when the gynecological sample analyzer is in a third detection mode state, the control device is used for:

controlling the sample introduction device to provide sample liquid to be detected, and controlling the first scanner to identify and acquire detection information of the sample liquid to be detected; the card bin mechanism is controlled to output the detection card, and the second code scanner is controlled to identify the information of the detection card;

controlling the gynecological analysis device to perform the first detection process on the sample liquid to be detected on the detection card;

when the gynecological analysis device finishes or does not finish the first detection process, the gynecological analysis device controls the first rail to convey the sample liquid to be detected to the film reading device, controls the third code scanner to identify and acquire detection information of the sample liquid to be detected, and judges whether the information acquired by the first code scanner and the information acquired by the third code scanner are consistent;

controlling the second track to convey the detection card or the bearing piece to the film reading device;

if the second type of detection card is conveyed by the second track, controlling the fourth code scanner to identify the information of the second type of detection card; if the second track is used for conveying the bearing piece, controlling the printing unit to print the information acquired by the first code scanner on the bearing piece;

judging whether the detection information of the sample liquid to be detected corresponds to the information of the second type detection card or the bearing piece according to the detection information of the sample liquid to be detected and the information of the second type detection card or the bearing piece;

and if the detection information of the sample liquid to be detected corresponds to the information of the second type detection card or the bearing piece, controlling the slide reading device to perform a second detection flow.

17. The gynecological sample analyzer of claim 1, wherein the first sample analysis result comprises a dry chemistry analysis result and a microscopy analysis result; and/or, the second sample analysis results comprise micro-ecological morphology analysis results; and/or the third sample analysis results comprise dry chemistry analysis results, microscopic analysis results, and micro-ecological morphology analysis results.

18. The gynecological sample analyzer of claim 17, wherein the dry chemistry analysis results include at least pH, hydrogen peroxide, leukocyte esterase, lactate, oxidase, sialidase, β -glucuronidase, acetylglucosaminidase, proline aminopeptidase, alkaline phosphatase, coagulase detection results; and/or the presence of a gas in the gas,

the microscopic examination analysis result at least comprises cell cleanliness, white blood cell number, pus cell number, red blood cell number and clue cell detection result; and/or the presence of a gas in the gas,

the micro-ecological morphology analysis result at least comprises: epithelial cells, flora density, lactobacillus proportion, flora diversity, other miscellaneous bacteria proportion, mycoplasma-like corpuscle, chlamydia-like corpuscle, intracellular G-diplococcus, treponema pallidum, blastospores, hyphae, clue cells, trichomonas, white blood cells, red blood cells, campylobacter morphotropis, gram negative bacilli, gardner's bacillus/Bacteroides, cocci and other detection results.

19. A gynecological sample analyzer, comprising:

the slide reading device comprises a slide making and dyeing mechanism and a slide reading mechanism, wherein the slide making and dyeing mechanism is used for executing at least one of slide making operation and dyeing operation on the sample liquid to be detected so as to obtain a target bearing piece; the film reading mechanism is used for carrying out image acquisition and analysis on the target bearing piece; the first track is connected with the gynecological analysis device and the film reading device;

the control device is used for controlling the first track to convey the sample liquid to be detected to the gynecological analysis device and/or the film reading device so as to realize specific project detection, and the control device is also used for:

controlling the gynecological analysis device and/or the film reading device to execute a detection flow matched with the detection mode on the sample liquid to be detected according to the detection mode;

when the gynecological sample analyzer is in the second detection mode state, the control device controls the first rail to convey the sample liquid to be detected to the film reading device, the film reading device executes a second detection flow on the sample liquid to be detected, and a second sample analysis result of the sample to be detected is obtained after the second detection flow is executed;

when the gynecological sample analyzer is in the third detection mode, the control device controls the first rail to convey the sample liquid to be detected to the gynecological analysis device and the film reading device respectively, and the gynecological analysis device and the film reading device execute a third detection flow on the sample liquid to be detected so as to obtain a third sample analysis result of the sample to be detected after the third detection flow is executed;

when the gynecological sample analyzer is in the first detection mode, the control device is used for:

20. A gynecological sample analysis method is characterized by being applied to a gynecological sample analyzer, and the gynecological sample analyzer comprises: the sample feeding device is used for providing a sample to be detected and eluting the sample to be detected to form sample liquid to be detected, and comprises a first track for bearing and conveying the sample to be detected and the sample liquid to be detected; the gynecological analysis device is used for detecting gynecological secretion of the sample liquid to be detected; the slide reading device comprises a slide making mechanism, a dyeing mechanism and a slide reading mechanism, wherein the slide making mechanism is used for making the sample liquid to be detected into a slide to obtain a sample bearing member; the dyeing mechanism is used for dyeing the sample bearing piece to obtain a target bearing piece; the film reading mechanism is used for carrying out image acquisition and analysis on the target bearing piece; the first track is connected with the gynecological analysis device and the film reading device; the sample analysis method comprises the following steps:

the first track is controlled to convey the sample liquid to be detected to the gynecological analysis device and/or the film reading device so as to realize specific item detection, and the method further comprises the following steps: