CN114681165B

CN114681165B - Locking structure and outer anchor for left ventricle volume-reducing device

Info

Publication number: CN114681165B
Application number: CN202210410404.2A
Authority: CN
Inventors: 王焱; 王斌; 陈翔; 熊忠亮; 姜程文; 梁玉晨; 张梅慧
Original assignee: Chenxing Nantong Medical Instrument Co ltd
Current assignee: Chenxing Nantong Medical Instrument Co ltd
Priority date: 2022-04-19
Filing date: 2022-04-19
Publication date: 2024-03-19
Anticipated expiration: 2042-04-19
Also published as: CN114681165A

Abstract

The invention discloses a locking structure and an outer anchor for a left ventricular volume-reducing device, wherein the locking structure is provided with a locking unit, and the locking unit is provided with: the locking device comprises a locking piece capable of being propped against a tie rod, a pressing piece capable of pressing the locking piece on the tie rod, a pair of resetting pieces capable of bouncing the locking piece away from the tie rod and a shell, wherein the locking unit is arranged in the shell, two opposite first shell walls of the shell are respectively provided with two resetting support holes which are respectively fixedly connected with two ends of the corresponding resetting pieces, and the resetting pieces are provided with supporting force. The invention further reduces the risk of the outer anchor slipping off the tie rod by making structural improvements in the locking structure, and retrieves the outer anchor by unlocking the locking structure.

Description

Locking structure and outer anchor for left ventricle volume-reducing device

Technical Field

The invention belongs to the technical field of medical appliances, and particularly relates to a locking structure and an outer anchor for a left ventricular volume-reducing device.

Background

When a heart attack occurs, the transport of blood, oxygen and nutrients is blocked. This results in slow death of heart tissue, and some of the beating muscles are replaced by inert scar tissue. After a heart attack, the heart increases for a short period of time to maintain blood flow and human life, but over time scar tissue begins to engulf the heart and weaken the heart muscle. Common interventions such as coronary stenting and drug therapy do not address this problem. The left ventricular volume reduction device is a transcatheter ventricular enhancement system and can be used for solving the scar tissue problem of patients with ischemic cardiomyopathy after myocardial infarction. It embeds a series of anchors into the ventricular wall, suturing excess scar tissue to assist the heart in restoring its previous shape and function. At present, the device has been shown to remodel the ventricles, helping to improve cardiac function, patient symptoms and quality of life.

The left ventricular volume reduction device delivers multiple pairs of anchors into the body. They clamp the left ventricle and allow other surgical instruments to enter the heart through small incisions in the body surface. Such minimally invasive systems may also be used in conventional open chest procedures to effect ventricular repair. Especially for frail patients. However, the left ventricular volume reduction device is not recyclable in the market at present, once the left ventricular volume reduction device is required to be removed due to failure of an operation or other reasons, a doctor has to take an operation with higher risk such as happy heart on a patient, and a great economic burden is caused to the patient and family members of the patient, and even the life of the patient is endangered, so that the implanted left ventricular volume reduction device with abundant functions, simple operation and recycling is necessary to be developed, and the vast patient and family members of the patient are benefited. On the other hand, the tie rod of the existing left ventricle volume-reducing device is inserted on the outer anchor, and the outer anchor is easy to fall off in the heart beating process, so that larger hidden trouble is easily caused.

Disclosure of Invention

The invention aims at solving the technical problem that the existing left ventricular volume reduction device is easy to fall off in the heart beating process, and aims to provide a locking structure for the left ventricular volume reduction device.

The locking structure for a left ventricular volume-reducing device of the present invention has a locking unit having:

a locking member which can be pressed against the tie bar;

a compression member for compressing the locking member against the tie rod.

Preferably, the locking unit further has a pair of return members for urging the locking member away from the tie bar.

Preferably, the locking structure further has:

the shell is internally provided with the locking unit, two opposite first shell walls of the shell are respectively provided with two reset supporting holes, and the two reset supporting holes are respectively fixedly connected with two ends of a corresponding reset piece to provide supporting force for the reset piece.

Preferably, the two opposite first and second walls of the housing have compression holes therein, the compression holes being connected to the compression member, the compression holes being used to limit or provide support to the compression member.

Preferably, the two opposite first or second walls of the housing each have a tie rod aperture therein for the tie rod to pass through.

Preferably, a first side of the locking member is a toothed surface that is abuttable against the tie bar.

Preferably, the locking elements have locking tips on opposite second sides thereof, respectively, which are adapted to interact with the compression member.

Preferably, the compression member comprises:

the three-end connecting rods are respectively positioned on two opposite second side surfaces of the locking piece, and the first end rods of the three-end connecting rods are in mutual pressing contact with the locking tip ends of the locking piece;

the pair of extrusion shafts are respectively arranged on the second end rod of the three-end connecting rod in a penetrating way;

one end of the compression spring ring is fixedly connected to one side wall of the third end rod of the three-end connecting rod.

Preferably, the pressing hole includes:

the two pairs of extrusion shaft supporting holes are respectively arranged on two opposite second shell walls of the shell, two ends of the extrusion shaft are respectively fixedly connected in the extrusion shaft supporting holes, and the extrusion shaft supporting holes provide supporting force for the extrusion shaft;

a pair of compression spring support holes provided on two opposite first case walls of the case, respectively; the other end of the compression spring ring is fixedly connected in the compression spring supporting hole, and the compression spring supporting hole provides supporting force for the compression spring ring.

Preferably, the reset member includes:

The resetting bosses are respectively fixed on the two opposite third side surfaces of the locking piece;

and the two ends of the reset spring strip are respectively and fixedly connected in reset supporting holes of two opposite first shell walls of the shell, and the reset supporting holes provide supporting force for the reset spring strip.

Preferably, the locking piece is in a cuboid shape, a cylindrical inner cavity is formed in the other first side face of the locking piece, and an inner threaded interface capable of being connected with the locking piece is formed in the inner surface of the cylindrical inner cavity.

Preferably, the locking unit further has a cam having:

the cam body is arranged on the other first side surface of the locking piece;

the two peripheral bosses are symmetrically fixed on the outer side of the cam main body.

It is preferred that the first and second heat sinks,

the axle center of the cam main body is provided with a cam through hole for providing a lock release piece channel;

the end face of the cam main body is provided with a pair of clamping grooves which are buckled with the locking and releasing piece.

Preferably, a third wall of the housing is provided with a circular aperture for defining the cam body of the cam.

Another object of the present invention is to provide an outer anchor for a left ventricular volume reduction device having:

an outer anchor body in the shape of a prolate cube;

the locking structure is used for the left ventricular volume reduction device and fixedly arranged at the center of one side surface of the outer anchor body.

Preferably, the outer anchor body has:

a contact surface which can be abutted against the outer wall of the left ventricle; and

and the non-contact surface is opposite to the contact surface, and the locking structure is fixed at the center of the non-contact surface.

Preferably, the center of the outer anchor body is provided with a through lock hole, the lock hole is used for penetrating the tie bar, and the first or second shell wall of the shell of the locking structure is fixedly arranged at the lock hole of the outer anchor body.

The invention has the positive progress effects that:

1. the invention further reduces the risk of the outer anchor slipping off the tie rod by structural modification in the locking structure and retrieves the outer anchor by unlocking the locking structure.

2. According to the invention, the locking structure with the tooth-shaped surface is arranged on the outer anchor, and the gripping force of the outer anchor and the tie rod is improved through the tooth-shaped surface, so that the risk of falling off of the outer anchor in a body is improved.

3. According to the invention, the barbs are arranged on the non-contact surface of the inner anchor, so that the inner anchor can be pulled out of the body from the delivery sheath by only using the barbs hung on the inner anchor by the snare when the operation fails or the inner anchor needs to be taken out later, and the open chest operation is not needed, so that the invention has the function of secondary intervention recovery, increases the fault tolerance of the operation, lightens the economic burden of a patient, avoids high risk operations such as open heart operation and the like, and benefits the patient.

Drawings

FIG. 1 is a schematic perspective view of a left ventricular volume reduction device according to the present invention;

FIG. 2 is a schematic view of the structure of the tie bar 10 of the present invention;

FIGS. 3A to 3D are schematic views showing the structure of the recoverable inner anchor according to the present invention;

FIG. 3E is a schematic view of the recovery process of the recoverable inner anchor of the present invention;

FIG. 4A is a schematic perspective view of another example left ventricular volume reduction device according to the present invention;

FIGS. 4B-4C are schematic perspective views of a collapsible delivery inner anchor of the present invention;

FIG. 4D is a schematic illustration of the delivery process of the collapsible delivery inner anchor of the present invention;

FIGS. 5A-5B are schematic perspective views of an outer anchor according to the present invention having a locking structure 31;

FIGS. 5C-5D are schematic exterior perspective views of the locking structure 31 of the present invention (only the locking portion housing is shown, the housing containing the tie bar hole portions is not shown);

FIGS. 5E-5G are schematic views of the inner locking portion of the locking structure 31 of the present invention;

FIGS. 6A-6B are schematic structural views of the locking structure 32 of the present invention (only the locking portion and its housing, the housing containing the tie bar hole portions not shown);

FIG. 6C is a schematic view of the internal locking portion of the locking structure 32 of the present invention;

FIGS. 7A-7B are schematic perspective views of an outer anchor according to the present invention having a locking structure 33;

fig. 7C is a schematic view of the structure of the inner locking portion of the locking structure 33 of the present invention;

FIG. 7D is a schematic view of the structure of the locking structure 33 of the present invention (only the locking portion and its housing, the housing containing the tie bar hole portions are not shown);

FIG. 8A is a schematic perspective view of an outer anchor incorporating locking structure 34 of the present invention;

FIGS. 8B-8C are schematic cross-sectional views of the locking structure 34 of the present invention (only the locking portion is shown, the tie bar hole portions are not shown);

fig. 9A to 9B are schematic structural views of the locking structure 35 of the present invention;

FIG. 9C is a schematic view of the locking structure 35 of the present invention threaded through the tie bar;

fig. 10A to 10D are schematic structural views of the implantation process of the left ventricular volume reduction device according to the present invention.

Detailed Description

In order that the manner in which the invention is practiced, as well as the features and objects and functions thereof, will be readily understood and appreciated, the invention will be further described in connection with the accompanying drawings.

In the field of interventional medical devices, "distal" is defined as the end of the procedure that is distal to the operator, and "proximal" is defined as the end of the procedure that is proximal to the operator.

In the present invention, unless explicitly specified and limited otherwise, the terms "mounted," "connected," "secured," and the like are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally formed; the device can be mechanically connected, electrically connected and communicated; either directly, or indirectly, through intermediaries, may be in communication with each other, or may be in interaction with each other, unless explicitly defined otherwise. The specific meaning of the above terms in the present invention can be understood by those of ordinary skill in the art according to the specific circumstances.

The locking and releasing piece refers to a device which can lock and unlock a locking structure in a conveying device.

As shown in fig. 1, the left ventricular volume reduction device of the present invention includes a tie rod 10, an inner anchor 20, and an outer anchor 30, the inner anchor 20 being hingeable at a distal end of the tie rod 10; an outer anchor 30 is provided to pass through the tie bar 10. The left ventricular volume reduction device provided by the invention embeds the inner and outer anchors into the ventricular wall and sutures the redundant scar tissue to help the heart restore its previous shape and function.

The tie rod of the present invention may be a conventional tie rod of the prior art, such as the straight rod shown in fig. 4A; alternatively, as shown in fig. 2, the tie rod 10 may have a square connecting section 11, a guide section 12 and a needle section 13 from the distal end to the proximal end, and the square connecting section 11, the guide section 12 and the needle section 13 may be integrally formed in the order from the distal end to the proximal end. The proximal needle segment 13 is made of a high hardness metal such as stainless steel or a polymeric material. The distal end of the connecting section 11 has a twisting hole 111. The axial centers of the guide section 12 and the needle 13 section are respectively provided with a guide wire channel which are communicated with each other. The leading section 12 has a guide hole 121 near the head end of the connecting section 11 for threading a guide wire into the guide wire channel. The tie bar 10 may be made of a polymer material such as stainless steel, platinum iridium alloy, or PEEK.

The inner anchor of the present invention may be any of the prior art inner anchors of any configuration that can be positioned on the right ventricular septum of the heart. However, in order to reduce the risk of open chest surgery after failure of the heart volume reduction device implantation procedure or after patient later removal of the left ventricular volume reduction device, the present invention provides an exemplary retrievable inner anchor 21. The body of the recyclable inner anchor 21 is substantially rectangular parallelepiped and has two sides, a contact surface 211 and a non-contact surface 212. The contact surface 211 is one surface attached to the right ventricular septum of the heart after implantation; the non-contact surface 212 is the surface that will not adhere to the heart after implantation, i.e., the surface opposite the contact surface 211. The axial center of the inner anchor 21 is provided with a guide wire cavity 213 through which a guide wire passes during operation delivery of the inner anchor, and the cross section of the guide wire cavity 213 can be square, round or any other hollow cavity, so long as the guide wire can pass through, and the guide wire is preferably a round through hole. The side end of the inner anchor 21 may be any smooth curved surface shape, preferably a spherical end surface, which is beneficial for the inner anchor 21 to smoothly enter the delivery sheath, so as to reduce the delivery resistance. The contact surface 211 may rest against the right ventricular septum. The contact surface 211 may be free of tie bar grooves as in the prior art, and the tie bar 10 is held against the contact surface 211 during the transfer of the inner anchor. In order to reduce the size of the delivery sheath, it is preferable that the contact surface 211 is provided with tie bar grooves 2111 along the axial direction, and the tie bar 10 is accommodated in the tie bar grooves 2111 during the delivery of the inner anchor, thereby reducing the volume of the inner anchor and the tie bar during the delivery; at the same time, the tie bar grooves 2111 limit the tie bar 10, and the tie bar 10 is restrained in the tie bar grooves 2111 to standardize the movement of the tie bar 10 and avoid damage to heart tissues. The tie rod 10 may be pivotally connected to the middle portion of the contact surface 211, preferably in a non-detachable manner, for example, the middle portion of the contact surface 211 has hinge portions 2112 respectively located at both sides of the tie rod groove 2111 and tie rod shafts 2113 for threading the tie rod 10 across the tie rod groove 2111, both ends of the tie rod shafts 2113 are respectively fixed to the middle portion of the hinge portions 2112, the hinge portions 2112 serve as supporting points for both ends of the tie rod shafts 2113, the tie rod shafts 2113 cannot be removed from the hinge portions 2112, and the twisting holes 111 of the tie rod 10 are threaded through the tie rod shafts 2113 on the inner anchors 21.

The non-contact surface 212 of the retrievable inner anchor 21 faces away from the contact surface 211. At least one side of the non-contact surface 212 extends toward the middle of the non-contact surface 212 with a barb 2121 extending generally parallel to the non-contact surface 212 to facilitate capture of the inner anchor 21 by the snare 91. Preferably, the opposite sides of the non-contact surface 212 each extend toward the middle of the non-contact surface 212 with barbs 2121 that are generally parallel to the non-contact surface 212, which are both more conducive to capture of the inner anchor 21 by the snare 91. Barbs 2121 extend from both sides of the non-contact surface 212, so that the cross section of the inner anchor is I-shaped, and the I-shaped cross section is beneficial to accumulating snare wires in the cavity of the I-shaped cross section of the inner anchor when the snare 91 drives the inner anchor 21 to withdraw, and reduces the resistance of withdrawing the inner anchor 21. The barb 2121 may be elongated, but the barb may be U-shaped to reduce endothelialization and attachment growth of the inner anchor 21 in the body for subsequent retrieval. The space between the barbs 2121 and the non-contact surface 212 forms a guiding lumen 2122 that can provide guidance for the snare 91. The recyclable inner anchor 21 is provided with barbs 2121 on the side of the inner anchor for hooking the snare 91, thereby pulling the inner anchor 21 back from the delivery sheath to complete the recycling of the inner anchor 21 without additional open surgery for taking the inner anchor. With barbs 2121 extending from both opposite sides of non-contact surface 212, the barbs 2121 on both opposite sides of non-contact surface 212 are spaced apart by a distance that is the distance between barbs 2121 is not aligned, and the distance forms barb openings 2123 that capture snare 91 into guide lumen 2122. The guide lumen 2122 extends from the barb opening 2123 along a straight line parallel to the non-contact surface 212 of the inner anchor, and when the guide lumen 2122 extends to a position near to the side end of the inner anchor 21 but not reaching the side end of the inner anchor 21, the guide lumen 2122 starts to bend and extend towards the axial center of the inner anchor 21, and finally the guide lumen 2122 ends at the axial center of the side end of the inner anchor 21, i.e. the guide lumen 2122 ends at the guide wire lumen 213 at the axial center. The arrangement is such that the snare 91 hanging in the guide lumen 2122 is in the central position of the inner anchor 21 when capturing the inner anchor 21, facilitating the guiding of the movement of the snare 91, and the snare is in the central position of the inner anchor 21 when capturing the inner anchor 21, facilitating the entry of the inner anchor 21 into the delivery sheath. And the barb 2121 has a guide bump 2124 protruding from the guide cavity 2122 near the end of the guide cavity 2122 for prompting the end of the guide. When the snare 91 is moved to this position, the capture of the inner anchor 21 by the snare is completed in conjunction with an external imager, and a corresponding operation of withdrawing the snare 91 can be performed. The inner anchor 21 of the present example may be integrally formed as a whole. The inner anchor material can be one or a combination of a plurality of metal materials with better biocompatibility and toughness, such as stainless steel, titanium, nickel-titanium alloy, and the like. The contact surface of the inner anchor or the whole inner anchor can be covered with a polyester coating or subjected to surface coating treatment, and the coating can buffer the contact between the inner anchor and heart tissue, and can increase endothelialization speed and reduce corresponding inflammatory reaction.

The internal anchors in the prior art have larger structural size in the conveying process, such as a technical scheme disclosed in U.S. invention "left ventricular volume reduction device" (application number: US10575953B 2): however, the inner anchor is not deformable, a large-size delivery sheath is required, and the delivery sheath cannot be recovered if the delivery sheath needs to be replaced after the delivery sheath is compressed, and the required delivery sheath has the size of 14F. While eastern venous vessels are generally smaller, the example of FIGS. 4A-4D provides a collapsible delivery inner anchor 22 that can be delivered into the heart using a 10F sized delivery sheath due to its collapsible reduced volume. The foldable conveying inner anchor 22 is fixed at the ventricular septum position of the right ventricle through the jugular vein, is made of any one or a plurality of combinations of stainless steel, nickel-titanium alloy, cobalt-chromium alloy and platinum-iridium alloy, can be attached with a coating film, is a single-layer film or a multi-layer film, and is made of one or a plurality of high polymer materials such as PET. The collapsible conveying inner anchor 22 has a two-sheet structure in which one sheet is a contact sheet 221 and the other sheet is a non-contact sheet 222. The non-contact piece 222 is slightly longer than the contact piece 221, and the non-contact piece 222 has an arc shape. Contact 221, as the name implies, is a piece that is attached to the right ventricular septum after implantation in the heart. The contact piece 221 and the non-contact piece 222 are made by any one or a combination of a plurality of riveting and welding processes. The contact tab 221 may rest against the right ventricular septum. The non-contact piece 222 is opposite to the contact piece 221. The contact piece 221 has a pair of hinge support holes 2211 at both ends, the non-contact piece 222 has hinge shafts 2221 at both ends, and both ends of the hinge shaft 2211 of the non-contact piece 222 are non-detachably penetrated into the hinge support holes 2211 of the contact piece 221. Vice versa, the non-contact piece 222 has a pair of hinge support holes at both ends, the contact piece 221 has hinge shafts at both ends, respectively, and both ends of the hinge shafts of the contact piece 221 are non-detachably penetrated into the hinge support holes of the non-contact piece 222, not shown. In this way, the two ends of the non-contact piece 222 are hinged to the two ends of the contact piece 221, and the whole inner anchor 22 forms a closed loop which can be folded into any shape due to the bending elasticity of the material of the non-contact piece 222 and the contact piece 221. For example, the non-contact tab 222 itself is aligned in half from the middle, and the contact tab 221 itself is also aligned in half from the middle, forming a fully symmetrical closed quadrilateral. In order to fully fold the middle parts of the contact piece 221 and the non-contact piece 222 together, a first U-shaped groove 2212 is formed in the middle part of the contact piece 221 towards the non-contact piece 222, a second U-shaped groove 2222 is formed in the middle part of the non-contact piece towards the contact piece, and the contact piece 221 and the non-contact piece 222 are folded more easily because the middle parts of the contact piece 221 and the non-contact piece 222 are dug into a U-shaped groove structure, so that the contact piece 221 and the non-contact piece 222 can be fully folded with themselves, namely, the closed quadrangle is further compressed to form two fully-folded parallel lines, the thickness after being folded in a conveying sheath tube is only the thickness of the two contact pieces 221 or the non-contact piece 222, the conveying volume is greatly reduced, the volume is reduced, the probability of vascular injury can be effectively reduced, and the safety of blood vessels is protected. The contact piece 221 has a hinge portion 2213 and a tie rod shaft 2214 for penetrating the tie rod 10 at both sides of the middle portion, and both ends of the tie rod shaft 2214 are fixed to the middle portion of the hinge portion 2213, respectively. The twisted hole 111 at the distal end of the tie rod 10 is threaded into the tie rod shaft 2214, and the tie rod shaft 2214 is fixedly connected in the twisted hole 111 without being detachable, such as by any one or a combination of a riveting process and a welding process. The middle portion of the non-contact tab 222 also has a threaded bore 2224 for the locking element to withdraw the inner anchor. When the procedure fails or is not suitable for implantation of a heart volume reduction device, the lock release is delivered to the delivery sheath before full release, i.e., before the inner anchor has not left the distal end of the delivery sheath, and the inner anchor 22 is withdrawn from the delivery sheath to the outside of the body by externally threading the head end of the lock release into the threaded bore 2224 of the non-contact tab 222. The inner anchor 22 of the present example is also recyclable. The contact piece 221 and the non-contact piece 222 also have a guide wire hole 2215 and a guide wire hole 2225, respectively, for a guide wire to pass through.

The external anchor of the present invention may be any of the prior art external anchors of any configuration for excluding left ventricular scar structures. As shown in fig. 5A-5B, one of the outer anchors, such as outer anchor 30, is generally flat, cuboid in shape, having an outer anchor body 30a that also has two sides, a contact surface and a non-contact surface, the contact surface being abuttable against the outer wall of the left ventricle, the non-contact surface being opposite the contact surface. The outer anchor body 30a has a through lock hole 30b at a central position thereof, and the tie bar 10 is inserted through the lock hole 30 b. The outer anchor material can be made of one or a plurality of metal materials with better biocompatibility and toughness, such as stainless steel, titanium, nickel-titanium alloy, cobalt-chromium alloy, platinum-iridium alloy and the like, and can also be used for covering a polyester coating on the contact surface of the outer anchor or the whole outer anchor body or carrying out surface coating treatment, and the coating structure is used for buffering the contact between the outer anchor and heart tissue, so that the endothelialization speed can be increased, and the corresponding inflammatory reaction can be lightened.

In order to enhance the firmness of locking the outer anchor 30 to the tie bar 10, the locking structure is provided on the non-contact surface of the locking hole 30b of the outer anchor body 30a, and the locking structure of the present invention may be any structure capable of tightly locking the outer anchor 30 and the tie bar 10 to each other. The locking structure of the present invention is illustrated with at least a locking member and a compression member, and preferably a reset member, or further cams, and further housings. The structure of the locking member, the pressing member, the restoring member, the housing, etc. may be varied, and any structure is possible as long as the locking member can be locked to the tie rod, and any structure is possible as long as the pressing member is capable of pressing the locking member to the tie rod 10, and the restoring member is capable of releasing the locking member from the tie rod, and any structure is possible for releasing the locking member.

As shown in fig. 5C to 5G, a locking structure 31 of an example of the invention has a locking unit having a locking member 311, a compression member 312, a pair of return members 313, and a cam 314, and a housing.

The main body of the locking piece 311 of this example has a substantially rectangular parallelepiped shape, and the locking piece 311 has a pair of first sides (i.e., two parallel sides facing away), a pair of second sides (another set of two parallel sides facing away), and a pair of third sides (yet another set of two parallel sides facing away). One of the first side faces of the locking member 311 is a tooth surface 3111, which is pressed against the square connecting section 11 of the tie rod 10 by the tooth surface 3111 of the locking member 311. The present example provides for a tight bite of the locking member on the tie bar without slipping by providing a first side of the locking member with a toothed surface, increasing the gripping force to reduce the risk of the outer anchor slipping off the tie bar 10, and increasing the locking strength. The locking member 311 has locking tips 3112 on opposite second sides that interact with the compression members to provide for both maintenance and unlocking. The other first side of the locking member 311 (i.e., the side opposite to the tooth surface 3111) has a cylindrical inner cavity, and the inner surface of the cylindrical inner cavity has an internal threaded interface 3113 connectable to the locking member, and the external locking member is pushed and pulled, so that the locking member 311 is pushed and pulled, and locking and releasing of the locking structure 31 are achieved.

Compression member 312 of the present example includes a pair of three-terminal links 3121, a pair of compression shafts 3122, and a pair of compression coils 3123. The three-end connecting rods 3121 are respectively located at two opposite second sides of the locking member 311, the first end rod of the three-end connecting rod 3121 and the locking tip 3112 of the locking member 311 are mutually pressed to form surface-to-surface contact, and the pressing member 312 can firmly press the locking member 311 on the tie rod 10 by pressing the locking tip 3112 downward through the first end rod of the three-end connecting rod 3121. The pressing shafts 3122 are respectively arranged on the second end rods of the three-end connecting rods 3121 in a penetrating way; one end of compression spring 3123 is fixedly coupled to a side wall of the third end of three-end link 3121.

The return member 313 of the present example includes a return boss 3131 and a return spring bar 3132. The reset bosses 3131 are respectively fixed on two opposite third sides of the locking member 311, and may be integrally formed, for example; the return spring bar 3132 abuts against the lower side of the return boss 3131, and the return boss 3131 is provided with an upward elastic force, i.e., a return supporting force, against the pressure of the compression member 312 against the compression lock member by the return spring bar 3132. Thereby the tooth surface 3111 of the locking piece 311 is sprung away from the tie bar 10, unlocking the locking structure 31 and the tie bar 10 from each other.

The cam 314 of the present example has a cam body provided on the other first side surface of the lock piece 311; the cam 314 further has two peripheral bosses 3141 symmetrically fixed to the outer side of the cam body. The axial center of the cam body has a cam through hole 3142 providing a passage for the locking member, and the distal end of the locking member can be screwed to the female screw interface 3113 of the inner surface of the cylindrical cavity of the locking member 311 through the passage of the cam through hole 3142. The end surface of the cam body also has an engagement groove 3143 that engages with the lock release.

A locking unit is placed in the housing 315 of this example. The housing 315 has a pair of first housing walls, a pair of second housing walls, and a pair of third housing walls disposed opposite each other. The two opposite first walls of the housing 315 have two reset supporting holes 3151 respectively. The two ends of the return spring bar 3132 of the return member 313 are fixedly connected in the return support holes 3151 of the two opposite first housing walls of the housing 315, respectively, and the return support holes 3151 provide a rebound upward support force to the return spring bar 3132 so as to cause the tooth surface 3111 of the locking member 311 to spring away from the surface of the square connecting section 11 of the tie bar 10. The two opposite first walls and the two opposite second walls of the housing 315 have compression holes connected to the compression member for limiting the compression member or providing support force to the compression member, specifically, the compression holes include two pairs of compression shaft support holes 3152 and a pair of compression spring support holes (located on the inner wall of the housing, not penetrating the outside of the housing, so not shown). Two pairs of pressing shaft supporting holes 3152 are respectively arranged on two opposite second shell walls of the shell 315, two ends of the pressing shaft 3122 are respectively fixedly connected in the pressing shaft supporting holes 3152, and the pressing shaft supporting holes 3152 provide supporting force for the pressing shaft 3122; the compression spring support holes are respectively provided on the inner walls of the two opposite first housing walls of the housing 315, and the other ends of the compression spring coils 3123 are fixedly connected in the compression spring support holes, and the compression spring support holes provide a supporting force, such as a pushing force or a pulling force, for the compression spring coils 3123. The housing 315 has first or second opposite walls each having a tie bar aperture 3154 therethrough for the tie bar 10 to pass through. A third wall of the housing 315 is provided with a circular aperture 3155, the circular aperture 3155 providing a cam body defining the cam 314.

The lock release process of the lock structure 31 of the present example is as follows: the release member is threaded through the boss through hole 3142 of the boss 314 at the distal end, is connected to the internal threaded interface 3113 in the locking member 311 of the locking structure 31 by distal end thread, and further pushes the tooth surface 311 of the locking member 311 to be attached to the square connecting section 11 of the tie rod 10, at this time, the first end rod of the three-end connecting rod 3121 is tightly abutted against the surface of the locking tip 3112 of the locking member 311 due to the pushing force of the pressing spring coil 3123, and the locking tip 3112 is integrally formed on the locking member 311, driving the tooth surface 3111 of the locking member 311 to be engaged on the tie rod 10. When the peripheral boss 3142 of the boss 314 is located on the third side of the locking member 311, the locking structure 30 is in the locked state.

When unlocking is needed, the locking piece is snapped onto the snap-fit groove 3143 of the boss 314 through the distal end, after the boss 314 rotates by 90 degrees, the peripheral boss 3141 is rotated to the second side face of the locking piece 311, and at this time, the three-end link 3121 performs lever motion, the peripheral boss 3141 pushes the other side wall of the third end link of the three-end link 3121, that is, the compression spring 3123 contacts the other side wall of the side wall, so as to push the compression spring 3123 to a compressed state, at this time, the compression shaft 3122 is used as the axis to drive the first end link of the three-end link to tilt up, thereby releasing the locking tip 3112 of the locking piece 311, pushing the reset boss 3131 to move up under the reset spring bar 3132 of the reset piece 313, and the tooth-shaped face 3111 of the first side face of the locking piece 311 is far away from the tie bar, thereby releasing the tie bar 10.

When the boss 314 continues to rotate, the peripheral boss 3141 is separated from the other side wall of the third end rod of the three-end connecting rod 3121, and pushes the external locking member 311, and the three-end connecting rod 3121 automatically resets under the action of the compression spring coil 3123, and locks the locking member 311, thereby completing the locking of the locking structure 31 to the tie rod 10. The locking structure 31 is reliable in locking, has an automatic reset function, and is simple to operate.

As shown in fig. 6A-6C, another locking structure 32 of the present invention is illustrated having a locking unit with a locking member 321, a compression member 322, and a pair of return members 323, but without the cams in the locking structure 31, and a housing 324.

In this example, the body of the locking member 321 is also generally rectangular in shape with two first sides facing away from each other, one of which is a toothed surface 3211. This toothed surface 3211, like the locking structure 31, allows the locking member 321 to be snapped tightly onto the tie rod 10 without slipping, improving the gripping force to reduce the risk of the outer anchor slipping off the tie rod 10. The locking piece 321 has a locking convex bar 3212 at the middle of the other first side.

The main body of the press material 322 of this example is also a slider having a substantially rectangular parallelepiped shape, and the middle of the side of the press material 322 opposite to the other first side of the lock member 311 has a barrier rib 3221, and the barrier rib 3221 can be slid back and forth between the both sides of the lock rib 3212. However, the side surfaces of the press body 322 have a constant level difference on the opposite surfaces of the barrier rib 3221, specifically, the opposite surfaces of the barrier rib 3221 on the opposite surfaces of the press body 322 are divided into a lock surface 3222 and a release surface 3223 by the barrier rib 3221, and the distance between the release surface 3223 and the apex of the barrier rib 3221 is greater than the distance between the lock surface 3222 and the apex of the barrier rib 3221. The compression member 322 has a threaded interface 3224 on a side thereof that is connectable to a release member.

The restoring member 323 of the present example includes a restoring boss 3231 and a restoring spring bar 3232, and the restoring boss 3231 may be fixed to the opposite second side surfaces of the locking member 321, and fixed to the third side surface, respectively. Such fixing may be integrally formed on the side of the locking member 321. The return spring bar 3232 abuts against the return boss 3231, and the return spring bar 3232 provides a return supporting force in a rebound direction to the return boss 3231.

The locking unit is disposed in the housing 324 of the locking structure 32 of this example, and the housing 324 has two first housing walls disposed opposite to each other, two second housing walls disposed opposite to each other, and two third housing walls disposed opposite to each other. Two opposite first shell walls or second shell walls of the shell 324 are respectively provided with two reset supporting holes 3241, the reset supporting holes 3241 are respectively fixedly connected with two ends of the reset spring strip 3232 of the reset piece 323, and the reset supporting holes 3241 provide reset supporting force for the reset spring strip 3232 in rebound. The two opposing first or second walls of housing 324 have slide block openings 3242, respectively, for limiting the direction of sliding movement of compression member 322, the slide block. The two opposite first or second housing walls of the housing 324 have tie bar holes (the housing portions provided with the tie bar holes are not shown in the drawing) respectively at corresponding positions where the locking pieces 321 lock the tie bars 10.

The lock structure 32 of the present example achieves the lock release process of: the locking ribs 3212 of the locking member 321 are slidably engaged with the barrier ribs 3221 on the opposite side of the pressing member 322, and the barrier ribs 3221 on the opposite side of the pressing member 322 are pushed over the locking ribs 3212 of the locking member 321, so that the locking ribs 3212 of the locking member 321 abut against the locking surfaces 3222 of the pressing member 322, and both ends of the pressing member 322, that is, the sliding blocks, are limited by the sliding block openings 3242 of the housing 324, and at this time, the locking surfaces 3222 bring the locking member 321 into a pressed state due to the short distance between the locking surfaces 3222 and the apexes of the barrier ribs 3221, so that the tooth surfaces 3211 of the locking member 321 are snapped onto the direction connecting rods 11 of the tie bars 10.

When it is desired to release locking structure 32, the distal end of the release member is threaded onto threaded interface 3224 of compression member 322, and barrier cam 3221 of compression member 322 is passed over locking rib 3212 by pulling the release member outwardly, such that locking rib 3212 of locking member 321 abuts against release surface 3223 of compression member 322, and locking rib 3212 is not exposed to external pressure due to the greater distance between release surface 3223 and the apex of barrier rib 3221. Due to the rebound reset action of the reset spring bar 3232 of the reset member 323, the push reset boss 3231 moves upward, so that the tooth-shaped surface 3211 of the locking member 321 integrally connected with the reset boss 3231 is separated from the square connecting section 11 of the tie bar 10, and the tie bar 10 is unlocked from the outer anchor. Vice versa, when the lock release is pushed inwardly, the locking rib 3212 contacts the locking surface 3222 beyond the barrier rib 3221, and the locking structure is in the locked state. The release and locking of the tie rod by the outer anchor can be realized by utilizing the push-pull of the locking release piece to complete the switching between the release state and the locking state.

As shown in fig. 7A-7D, yet another example locking structure 33 of the present invention has a locking unit with a locking member 331, a compression member 332, and a pair of return members 333, but without the cams in the locking structure 31, and a housing 334.

The lock 331 of this example has a generally rectangular parallelepiped shape in shape and is generally identical in structure and shape to the lock 321 in the lock structure 32. Specifically, the locking member 331 has two first side surfaces facing away from each other, one of the first side surfaces being a toothed surface 3311. The toothed surface 3311, like the locking mechanism 32, allows the locking member 331 to be tightly engaged to the tie rod 10 without slipping, improving the gripping force to reduce the risk of the outer anchor slipping off the tie rod 10. The locking piece 331 has a locking protrusion 3312 at the middle of the other first side.

Compression member 332 of the present example is configured differently than compression member 322 of locking structure 32, but the lock release process is substantially similar. Compression member 332 is a generally cylindrical slide block having opposed sides of compression member 332 with locking recess 3321 and release recess 3322, and locking tab 3312 of locking member 331 is receivable within locking recess 3321 or release recess 3322 and is slidably movable back and forth between locking recess 3321 or release recess 3322. The release recess 3322 and the locking recess 3321 may be crossed with each other, for example, by 90 degrees, or an angle smaller than 90 degrees is also possible. The depth of the release groove 3322 is greater than the depth of the locking groove 3321. The compression member 332, i.e., the back of the slider, has a stop 3323 thereon. The compression member 332, i.e., the back of the slider, has an engagement slot 3324 thereon for connection to the release member.

The return 333 of the present example includes a return boss 3331 and a return spring strip 3332. The reset protrusions 3331 are respectively fixed on two opposite second or third sides of the locking piece 331, and may be integrally formed on the sides of the locking piece 331. The return spring bar 3332 abuts against the lower portion of the return boss 3331, and the return spring bar 3332 provides a return supporting force for the return boss 3331.

The locking unit is disposed in the housing 334 of this example, the housing 334 has two opposite first housing walls, two second housing walls and a third housing wall, and two return support holes 3341 may be respectively disposed on the two opposite first housing walls or the two opposite second housing walls, and are respectively fixedly connected to two ends of the return spring bar 3332 of the corresponding return member 333, and the return support holes 3341 provide a supporting force for rebound return to the return spring bar 3332. The third wall of the outer casing 334 has a sliding block opening 3342, and a fan-shaped limiting opening 3344 for limiting the limiting member 3323 is provided at the periphery of the sliding block opening 3342 to provide a limiting function of the rotary compressing member 322. The two opposite first or second walls of the housing 334 have tie bar holes 3343, respectively, at corresponding locations where the locking member 331 locks the tie bar 10.

The locking and releasing process of the locking structure 33 of this example is as follows:

The locking ribs 3312 of the locking member 331 are in a rotating fit with the opposite surfaces of the pressing member 332, the locking grooves 3321 on the opposite surfaces of the pressing member 332 are pushed onto the locking ribs 3312 of the locking member 331, so that the locking ribs 3312 of the locking member 331 abut against the locking grooves 3321 of the pressing member 332, and the pressing member 332 is limited by the wall around the sliding block opening 3342 of the outer shell 334, at this time, the locking grooves 3321 are shallow in depth, namely, the locking grooves 3321 enable the locking member 331 to be in a pressed state, so that the tooth-shaped surfaces 3311 of the locking member 331 are snapped onto the directional connecting rods 11 of the tie bars 10.

When the locking structure 33 needs to be released, the distal end of the locking member is snapped onto the engaging groove 3324 of the pressing member 332, and the releasing groove 3322 of the pressing member 332 is abutted against the locking protrusion 3312 of the locking member 331 by rotating the locking member, and the locking protrusion 3312 is not subjected to external pressure due to the large depth of the releasing groove 3322. Due to the rebound reset action of the reset spring bar 3332 of the reset member 333, the push reset boss 3331 moves upward, so that the tooth surface 3311 of the lock 331 integrally connected with the reset boss 3331 is separated from the square connecting section 11 of the tie bar 10, thereby unlocking the tie bar 10 from the outer anchor.

As shown in fig. 8A-8C, a further exemplary locking structure 34 of the present invention has a locking member 341 and a compression member 342, and may be devoid of a reset member, or of course, a reset member 343, and no housing, the function of which is provided by the compression member 342.

The locking member 341 of the present example is generally rectangular and is disposed through the compression member 342. The locking member 341 has two opposite bottom surfaces, one of which is a toothed surface 3411. This toothed surface 3411, like the structure and function of the toothed surfaces of the locking structures 31, 32, 33, 34, allows the locking member 341 to be firmly engaged against the tie rod 10 without slipping, improving the gripping power to reduce the risk of the outer anchor slipping off the tie rod 10. The other bottom surface of the locking member 341 has a screw groove 3413 to which the locking member can be coupled. The side surface of the locking piece 341 has a locking protrusion 3412, and the locking protrusion 3412 may be two locking protrusions distributed at the same latitude, or may be at least two locking protrusions at the same latitude.

The compression member 342 of the present example is generally rectangular in shape, although it is equally possible to achieve the object of the present invention if the compression member 342 is generally cylindrical in shape, and the compression member 342 generally functions as a housing. The compressing member 342 is hollow inside, and the locking member 341 is inserted inside. The inner side of the squeeze member 342 has a blocking protrusion 3421, and the locking protrusion 3412 of the locking member 341 can be slidably switched back and forth on both sides of the blocking protrusion 3421 of the squeeze member 342, thereby having a squeezing function. The obstacle protrusions 3421 may be a corresponding number of obstacle protrusions at the same latitude, but may be fewer than the number of locking protrusions. The obstacle convex portion 3421 may be at least two obstacle convex strips. The opposite inner walls of the compression member 342 have reset-support holes 3422. The compression member 342 is laterally open to provide access to the release member. The opposing walls of compression member 342 have tie rod bores 3423 therethrough at locations corresponding to tooth surfaces 3411 for the tie rods to pass through.

The return 343 has a return boss 3431 and a return spring bar 3432, if present. The reset boss 3431 is fixed to opposite sides of the locking member 341, and the reset boss 3431 may be integrally formed to opposite sides of the locking member 341. The return spring bar 3432 abuts under the return boss 3431, and the return spring bar 3432 provides a rebound return support force to the return boss 3431. The two ends of the return spring bar 3432 are fixedly connected in the return support holes 3422 of the opposite inner walls of the compression member 342, respectively, and the return support holes 3422 provide support force for the return spring bar 3432.

The locking and releasing process of the locking structure 34 of this example is as follows:

the tooth surface of the locking member 341 is pressed against the tie bar 10 while the locking protrusion 3412 of the locking member 341 is pushed over the barrier protrusion 3421 of the press member 342, and the tooth surface of the locking member 341 is tightly engaged on the square connecting portion of the tie bar 10 due to the pressing force, thereby achieving the locking process.

When the locking structure 34 is to be released, it is screwed into the threaded recess 3413 of the locking member 341 by the distal end of the locking member, and since the locking protrusion 3412 and the obstacle protrusion 3421 are made of a material having a slightly soft property in the hard and medium, the locking member 341 is pulled out of the compression member directly from the compression member by the locking member via the threaded recess 3413, and at this time, since the locking protrusion 3412 and the obstacle protrusion 3421 have a slightly soft property and thus can be deformed, the locking member 341 can be pulled out of the compression member. This in turn pushes the toothed surface 3411 of the locking piece 341 away from the square connecting section 11 of the tie rod 10, thus completing the release process.

As shown in fig. 9A-9C, yet another locking structure 35 of the present invention differs from the previous locking structures 31, 32, 33, 34 in that only locking member 351 and compression member 352 are present, without additional return members and housings. Compression member 352 performs both the function of the reset member and the function of the housing.

The locking member 351 of this example is generally cylindrical, such as a locking bolt, and is disposed through the compression member 352. The locking member 351, i.e. a bottom surface of the locking bolt, has a toothed surface 3511 (not shown), which toothed surface 3511, like the toothed surfaces of the locking structures 31, 32, 33, 34, is structured and functionally effective to provide a tight engagement of the locking member 351 to the tie rod 10 without slipping, and to improve the gripping force to reduce the risk of the outer anchor slipping off the tie rod 10. The side of the locking member 351 has a locking external thread. The other bottom surface of the locking member 351 has an engagement groove 3513 to which the locking member is attachable.

The compression member 352 of the present example is also generally cylindrical in shape, although square shapes are also contemplated for purposes of the present invention. The compression member 352 has a tie rod hole 3521 extending through the entirety thereof for the tie rod to pass through. The press 352 also has a locking hole 3522 perpendicular to the axial direction of the tie rod holes 3521, the locking hole 3522 in the press 352 having locking internal threads that connect with locking external threads. The locking member 351, i.e., the locking bolt, is penetrated in the locking hole 3522. Tooth face 3511 of locking member 351 projects into tie rod bore 3521 of press member 352, and engaging groove 3513 of the other bottom face of locking member 351 projects out of press member 352.

The locking and releasing process of the locking structure 35 of this example is as follows:

the tie rod 10 is threaded into the tie rod bore 3521 of the press 351, the locking member 351 is inserted into the locking bore 3522 of the press 351, and the locking member 351 is screwed until its toothed surface 3511 compresses the square connecting segment 11 of the tie rod 10 against the side wall of the tie rod bore 3521, thus effecting a locking process.

When the tie rod 10 is to be released, the head end of the locking member is buckled on the buckling groove 3513 of the locking member 351, and the locking member 351 is reversely rotated to enable the locking member 351 to come out of the locking hole 3522, so that the tooth-shaped surface 3511 of the locking member 351 is not compressed any more to the tie rod 10, and the releasing function can be realized.

As shown in fig. 10A to 10D, the implantation process of the left ventricular volume reduction device of the present invention is as follows:

the proximal needle segment 13 or other piercing member on the tie rod 10 is used to complete the piercing of the left ventricular scar and the ventricular septum, enter the piercing sheath, establish a passageway between the right ventricle and the epicardial region, withdraw the dilator from the piercing sheath, enter the J-guidewire 92 along the piercing sheath, complete the capturing of the J-guidewire 92 with the snare 91 entering the delivery device, maintain the snare 91 in a cinched state with respect to the J-guidewire 92, withdraw the snare 91, pull the J-guidewire 92 into the lumen of the delivery device 90, and out the proximal end of the delivery device.

The puncture sheath is adjusted so that the distal end of the puncture sheath enters the distal lumen of the delivery device 90, the J-shaped guide wire 92 is advanced in vitro into the proximal needle segment 13 on the tie rod 10, the J-shaped guide wire 92 is advanced into the tie rod 10 connected to the inner anchor, the J-shaped guide wire 92 is held stationary, and the tie rod 10 is advanced so that the proximal end of the tie rod sequentially enters the lumen of the delivery device 90, the distal lumen of the puncture sheath, the distal end of the delivery device 90, the right ventricle, the left ventricle, and the epicardial region. When the proximal end of the tie rod 10 is epicardially withdrawn, the J-guidewire 92 may be withdrawn and the tie rod 10 pulled to complete the entry of the inner anchor 21.

The position of the inner anchor 21 is confirmed by imaging fluoroscopy and when the inner anchor 21 approaches the right ventricular septum site, the distal end of the puncture sheath is withdrawn to the left ventricle while the delivery device 90 is retracted so that the inner anchor 21 is released at the right ventricular septum site.

Cutting off the square connecting section 11 at the joint of the square connecting section 11 and the guiding section 12, adjusting the locking structure of the outer anchor 30 to enable the locking structure to be in a release state, enabling the locking structure to enter the outer anchor 30 along the square connecting section 11, and ensuring that the contact surface of the outer anchor 30 is contacted with scar tissue in an epicardial region.

The distance between the inner anchor and the outer anchor is shortened, meanwhile, the proper compression force of the heart is kept, the heart cannot be too large or too small, the optimal force is 1-6N, the external locking and releasing piece is operated, the locking structure is locked, the redundant square connecting section 11 is sheared, and the implantation of the left ventricular volume reduction device is completed. In combination with the anatomy and actual requirements of the patient's heart, the above steps are repeated, and a plurality of pairs of anchors, typically 2-4 pairs, can be implanted.

When the operation fails or the patient needs to remove the left ventricular volume reduction device, the dilator in the delivery device 90 is withdrawn, the snare 91 is taken along the delivery device 90, the barb opening 2123 on the inner anchor 21 is captured by the snare with the aid of the support of an imager, the barb 2121 of the inner anchor 21 is smoothly captured, the snare 91 is tightened, when the snare 91 contacts the guide bump 2124, the imager prompts the snare to complete capturing of the inner anchor, the locking of the outer anchor 30 to the tie bar 10 is released by the outer locking piece, the fastening state of the snare to the inner anchor 21 is maintained, the snare is withdrawn, the inner anchor 21 is completed to enter the delivery device 90, and the delivery device 90 is withdrawn, so that the interventional recovery of the inner anchor 21 can be completed.

The left ventricular volume reduction device provided by the invention takes surgical left chest minimally invasive incision and interventional right internal jugular vein as operation access, and after a guide wire is utilized to shuttle back and forth in the heart to lay a track in a state of no stop of the heart, two anchors are precisely arranged at the edge of a ventricular tumor like a tightening pocket, one left side, one right side, one inner side and one outer side are clamped, so that the ventricular tumor is folded and clamped, the scar part of the left ventricle and the right ventricle are folded together, a series of anchors are embedded into the ventricular wall, redundant scar tissues are sutured, so that the heart is helped to restore the previous shape and function, the left ventricle of a patient is remodelled to be close to the normal shape and size, the ventricle is remodelled, and the heart function, the symptoms and the life quality of the patient are helped to be improved. The left ventricular volume reduction device has the function of recycling intervention, so that open surgery is avoided in the process of surgery or when a patient needs to remove the left ventricular volume reduction device after surgery, and the like, secondary injury of the surgery to the patient is reduced in a recycling mode, and the economic burden of the patient and family members of the patient is reduced.

The foregoing has shown and described the basic principles, principal features and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, and that the above embodiments and descriptions are merely illustrative of the principles of the present invention, and various changes and modifications may be made without departing from the spirit and scope of the invention, which is defined in the appended claims. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims

1. A locking arrangement for a left ventricular volume reduction device, characterized in that the locking arrangement has a locking unit having:

a locking member which can be pressed against the tie bar;

a compression member for compressing said locking member against said tie rod;

a pair of return members that can spring the locking member away from the tie bar;

the locking structure comprises a shell, wherein the shell is internally provided with the locking unit, two opposite first shell walls of the shell are respectively provided with two reset supporting holes, and the two reset supporting holes are respectively fixedly connected with two ends of a corresponding reset piece to provide supporting force for the reset piece.

2. The locking structure for a left ventricular volume reduction device as claimed in claim 1 wherein two opposite first shell walls and two opposite second shell walls of said housing have compression holes therein, said compression holes being connected to said compression member, said compression holes being for limiting or providing support to said compression member.

3. The locking structure for a left ventricular volume reduction device as claimed in claim 1, wherein the two opposite first or second shell walls of the housing are respectively provided with a tie rod hole for the tie rod to pass therethrough.

4. The locking structure for a left ventricular volume reduction device as claimed in claim 2, wherein a first side of the locking member is a toothed surface that is abuttable against the tie rod.

5. A locking arrangement for a left ventricular volume reduction device as claimed in claim 2 wherein the locking member has locking tips on opposite second sides thereof which interact with the compression member.

6. The locking structure for a left ventricular volume reduction device as claimed in claim 5, wherein said compression member comprises:

7. The locking structure for a left ventricular volume reduction device as claimed in claim 6, wherein said compression hole comprises:

8. The locking structure for a left ventricular volume reduction device as claimed in claim 2, wherein the reset member comprises:

9. The locking structure for a left ventricular volume reduction device as claimed in claim 2, wherein the locking member has a rectangular parallelepiped shape in its outer shape, and the other first side of the locking member has a cylindrical inner cavity having an inner surface having an internal screw-threaded interface connectable with the locking member.

10. The locking structure for a left ventricular volume reduction device as claimed in claim 2, wherein the locking unit further has a cam having:

the cam body is arranged on the other first side surface of the locking piece;

11. The locking structure for a left ventricular volume reduction device as claimed in claim 10, wherein:

12. The locking structure for a left ventricular volume reduction device as claimed in claim 10, wherein: a third wall of the housing is provided with a circular aperture for defining the cam body of the cam.

13. An outer anchor for a left ventricular volume reduction device, comprising:

An outer anchor body in the shape of a prolate cube;

a locking structure, characterized in that: the locking structure is the locking structure for the left ventricular volume reduction device according to any one of claims 1 to 10, and the locking structure is fixedly arranged at a center position of one side surface of the outer anchor body.

14. The outer anchor for a left ventricular volume reduction device as claimed in claim 13, wherein the outer anchor body has:

15. The outer anchor for a left ventricular volume reduction device as claimed in claim 14, wherein the outer anchor body has a through locking hole at a central position thereof, the locking hole being provided for the tie rod to be penetrated therethrough, and the first or second shell wall of the housing of the locking structure is fixedly provided at the locking hole position of the outer anchor body.