CN103893344B - A kind of Chinese medicine ultra-fine powder for the treatment of yellow and white dysentery of piglet and preparation method thereof - Google Patents
A kind of Chinese medicine ultra-fine powder for the treatment of yellow and white dysentery of piglet and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine ultra-fine powder for the treatment of yellow and white dysentery of piglet, every 100 parts contain following component, Radix Pulsatillae 10-15 part, Rhizoma Coptidis 5-12 part, Radix Scutellariae 5-15 part, Cortex Phellodendri 7-15 part, Cortex Fraxini 5-10 part, Herba Pogostemonis 8-15 part, Radix Astragali 15-30 part, Rhizoma Atractylodis Macrocephalae 10-15 part, Radix Glycyrrhizae 10-15 part.The Chinese medicine ultra-fine powder for the treatment of yellow and white dysentery of piglet disclosed by the invention, by the synergism of various Chinese medicine ingredients, can cure mainly yellow and white dysentery of piglet, not only can dysentery relieving fast, and can strengthen pigling immunity, promotes piglet healthy growth; And Chinese medicine ultra-fine powder is pure Chinese medicinal preparation, safely, has no side effect; This Chinese medicine ultra-fine powder can be drunk water, can spice, easy to use.The invention also discloses a kind of Chinese medicine ultra-fine powder preparation method for the treatment of yellow and white dysentery of piglet, drug fiber and cell wall in fragmentation, active drug composition in release cells, improve drug level and utilization rate.
Description
Technical field
The invention belongs to animal drugs field, relate to a kind of Chinese medicine composition and preparation method thereof, be specifically related to a kind of Chinese medicine ultra-fine powder for the treatment of yellow and white dysentery of piglet and preparation method thereof.
Background technology
Yellow and white dysentery of piglet is the abbreviation of yellow scour of piglet, piglet pujos blancos, is that the one of the newborn piglet caused by pathogenic dust Xi Shi escherichia coli (E.Coli) is acute, height lethal infectious diseases.After escherichia coli enter intestine of young pigs, facility pili is adsorbed on intestinal mucosa, settles down propagation by this, produces a large amount of enterotoxin, piglet is dewatered and has loose bowels; It is characterized by violent diarrhoea, discharge yellow or yellow-white loose stool and rapid dehydration.
Usually, after piglet birth, the diarrhoea of 3-10 days is yellow scours, and the diarrhoea of being born more than 10 days is called Hakuri, also can judge by observing stool colour, the two is all a kind of acute infectious disease being caused newborn piglet by Escherichia coli, if treated not in time, be easy to cause piglet dead, bring huge economic loss to pig farm and raiser.
Summary of the invention
The object of the invention is to for above-mentioned the deficiencies in the prior art, a kind of Chinese medicine ultra-fine powder for the treatment of yellow and white dysentery of piglet is provided, not only can dysentery relieving fast, and can pigling immunity be strengthened.
Another object of the present invention is to provide a kind of preparation method for the treatment of the important superfine powder of yellow and white dysentery of piglet.
For achieving the above object, the technical scheme that the present invention takes is: provide a kind of Chinese medicine ultra-fine powder for the treatment of yellow and white dysentery of piglet, it is characterized in that: every 100 parts contain following component, Radix Pulsatillae 10-15 part, Rhizoma Coptidis 5-12 part, Radix Scutellariae 5-15 part, Cortex Phellodendri 7-15 part, Cortex Fraxini 5-10 part, Herba Pogostemonis 8-15 part, Radix Astragali 15-30 part, Rhizoma Atractylodis Macrocephalae 10-15 part, Radix Glycyrrhizae 10-15 part.
The Chinese medicine ultra-fine powder of above-mentioned treatment yellow and white dysentery of piglet, every 100 parts contain following component, the Radix Pulsatillae 10 parts, Rhizoma Coptidis 5 parts, Radix Scutellariae 10 parts, Cortex Phellodendri 7 parts, Cortex Fraxini 5 parts, Herba Pogostemonis 8 parts, the Radix Astragali 30 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, 15 parts, Radix Glycyrrhizae.
The Chinese medicine ultra-fine powder of above-mentioned treatment yellow and white dysentery of piglet, every 100 parts contain following component, the Radix Pulsatillae 15 parts, Rhizoma Coptidis 12 parts, Radix Scutellariae 10 parts, Cortex Phellodendri 10 parts, Cortex Fraxini 10 parts, Herba Pogostemonis 8 parts, the Radix Astragali 15 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, 10 parts, Radix Glycyrrhizae.
The Chinese medicine ultra-fine powder of above-mentioned treatment yellow and white dysentery of piglet, every 100 parts contain following component, the Radix Pulsatillae 10 parts, Rhizoma Coptidis 5 parts, Radix Scutellariae 12 parts, Cortex Phellodendri 8 parts, Cortex Fraxini 8 parts, Herba Pogostemonis 10 parts, the Radix Astragali 25 parts, the Rhizoma Atractylodis Macrocephalae 12 parts, 10 parts, Radix Glycyrrhizae.
The Chinese medicine ultra-fine powder of above-mentioned treatment yellow and white dysentery of piglet, every 100 parts contain following component, the Radix Pulsatillae 15 parts, Rhizoma Coptidis 7 parts, Radix Scutellariae 7 parts, Cortex Phellodendri 7 parts, Cortex Fraxini 5 parts, Herba Pogostemonis 12 parts, the Radix Astragali 20 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, 12 parts, Radix Glycyrrhizae.
A Chinese medicine ultra-fine powder preparation method for above-mentioned treatment yellow and white dysentery of piglet, is characterized in that: comprise the following steps:
A, selection, remove impurity by each raw material Radix Pulsatillae, Rhizoma Coptidis, Radix Scutellariae, Cortex Phellodendri, Cortex Fraxini, Herba Pogostemonis, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae and Radix Glycyrrhizae through selection respectively;
B, wash, put into medicine-washing machine by the medical material after selection, cleans surperficial dirt mud, dry;
C, cut medicine, the medical material dried is cut into decoction pieces through medicine cutter;
D, oven dry, drying equipment 100 ~ 105 DEG C of dryings 5 hours put into by the decoction pieces after being cut into;
E, batching, take each raw material decoction pieces after oven dry according to aforementioned proportion;
F, coarse pulverization, pulverize each raw material decoction pieces after taking through crusher for Chinese herbal medicine, and 40 mesh sieves obtain coarse powder excessively;
G, micronizing, by the coarse powder after coarse pulverization, put into super micron mill, crosses 500 mesh sieves and namely obtain superfine powder;
H, to pack, rearmounted for the superfine powder package encapsulation obtained shady and cool dry place is preserved.
Described drying equipment is Constant Temp. Oven.
The Radix Pulsatillae: Radix Pulsatillae bitter in the mouth, cold in nature; Return stomach, large intestine channel.There is heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery, effect of removing dampness and killing parasites.Clinical being mainly used in treats amebic dysentery, bacillary dysentery, trichomonas vaginitis and dysentery pus and blood etc.Modern pharmacological research finds that the Radix Pulsatillae has antitumor, strengthens immunologic function, antiinflammatory, resisting pathogenic microbes, parasiticide, protects the liver, toxicity and effect such as treatment endotoxemia etc.
Rhizoma Coptidis: GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.The diseases such as, vomiting damp and hot for retention of damp-heat in the interior, the intestines and stomach, dysentery.
Radix Scutellariae: bitter, cold.Return lung, gallbladder, spleen, stomach, large intestine, small intestine meridian.Heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive, blood pressure lowering.For hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood tells nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.
The similarities and differences of Rhizoma Coptidis and Radix Scutellariae is: Rhizoma Coptidis is partial to into the heart, is longer than Qinghuo Jiedu, and property is dry, is the agent of heart stomach, cure mainly vexation, doublely control epigastric oppression, lower profit, the thick intestinal of stomach can be adjusted, control dampness heat-dissipating, only quench one's thirst, separate Fructus Crotonis poison, arrogate to oneself except extreme misery mutually unrest disease and spread and flood card of a specified duration.Radix Scutellariae is then longer than clearing away lung-heat, though its property cold and not dry, to control heat cloudy raw wet, cures mainly dysphoria with smothery sensation and bleeder, that controls that gas heat attacks blood goes out blood disorder and little angina abdominis or abdominal pain in children, can be antiabortive and control and scald acute scleritis etc.Rhizoma Coptidis and Radix Scutellariae, similar temperament and respectively have speciality, therefore two medicine compatibilities then more can play synergism, and the damp and hot benefit in Qinghua shows.
Cortex Phellodendri: bitter, cold.Return kidney, bladder, large intestine channel.Heat clearing and damp drying, eliminating fire and detoxication, except hectic fever due to YIN-deficiency clearind deficient heat.For damp-heat dysentery, jaundice.
Cortex Fraxini: bitter in the mouth, cold.Return Liver Channel, gallbladder meridian, large intestine channel.Heat clearing and damp drying, liver heat removing and eyesight improving, for pyretic toxicity dysentery, astringent therapy dysentery relieving, leukorrhagia stopping.
Herba Pogostemonis: acrid in the mouth; Slightly warm in nature.Enter lung, spleen, stomach warp.Cure cold heat-damp in summer, cold and heat, and headache, breast gastral cavity painful abdominal mass is vexed, and vomiting is had loose bowels, malaria, dysentery, halitosis.
The Radix Astragali: Radix Astragali sweet in the mouth, slightly warm in nature, returns liver, spleen, lung, kidney channel.There is effect that benefiting QI for strengthening the superficies, arresting sweating are admittedly de-, hold in the palm skin ulcer granulation promoting, inducing diuresis to remove edema.There is the effects such as antiviral, anti-stress, antioxidation simultaneously, improve piglet immunity of organisms, promote body recovery.
The Rhizoma Atractylodis Macrocephalae: bitter in the mouth; Sweet; Warm in nature.Return spleen; Stomach warp.Invigorating the spleen and benefiting QI; Stomach invigorating, dampness diuresis; Reduce phlegm, hidroschesis; Antiabortive; Increase appetite.The Rhizoma Atractylodis Macrocephalae contains volatile oil, atractylol, Rhizoma Atractylodis ketone and health is had to the vitamin A of benefiting action.
Radix Glycyrrhizae: sweet in the mouth, property is put down, nontoxic.Radix Glycyrrhizae property is put down, and sweet in the mouth, returns 12 warps.There is removing toxic substances, eliminate the phlegm, pain relieving, spasmolytic is so that the pharmacological action such as anticancer.Coordinating the actions of various ingredients in a prescription.
The Chinese medicine ultra-fine powder for the treatment of yellow and white dysentery of piglet disclosed by the invention, by the synergism of various Chinese medicine ingredients, can cure mainly yellow and white dysentery of piglet, not only can dysentery relieving fast, and can strengthen pigling immunity, promotes piglet healthy growth; And Chinese medicine ultra-fine powder is pure Chinese medicinal preparation, safely, has no side effect; This Chinese medicine ultra-fine powder can be drunk water, can spice, easy to use.
The Chinese medicine ultra-fine powder preparation method for the treatment of yellow and white dysentery of piglet disclosed by the invention, drug fiber and cell wall in fragmentation, active drug composition in release cells, improves drug level and utilization rate.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in detail, but they are not to further restriction of the present invention.
The Chinese medicine ultra-fine powder for the treatment of yellow and white dysentery of piglet provided by the invention, every 100 parts contain following component, Radix Pulsatillae 10-15 part, Rhizoma Coptidis 5-12 part, Radix Scutellariae 5-15 part, Cortex Phellodendri 7-15 part, Cortex Fraxini 5-10 part, Herba Pogostemonis 8-15 part, Radix Astragali 15-30 part, Rhizoma Atractylodis Macrocephalae 10-15 part, Radix Glycyrrhizae 10-15 part.
Present invention also offers a kind of Chinese medicine ultra-fine powder preparation method for the treatment of yellow and white dysentery of piglet, comprise the following steps:
A, selection, remove impurity by each raw material Radix Pulsatillae, Rhizoma Coptidis, Radix Scutellariae, Cortex Phellodendri, Cortex Fraxini, Herba Pogostemonis, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae and Radix Glycyrrhizae through selection respectively;
B, wash, put into medicine-washing machine by the medical material after selection, cleans surperficial dirt mud, dry;
C, cut medicine, the medical material dried is cut into decoction pieces through medicine cutter;
D, oven dry, drying equipment 100 ~ 105 DEG C of dryings 5 hours put into by the decoction pieces after being cut into;
E, batching, take each raw material decoction pieces after oven dry according to aforementioned proportion;
F, coarse pulverization, pulverize each raw material decoction pieces after taking through crusher for Chinese herbal medicine, and 40 mesh sieves obtain coarse powder excessively;
G, micronizing, by the coarse powder after coarse pulverization, put into super micron mill, crosses 500 mesh sieves and namely obtain superfine powder;
H, to pack, rearmounted for the superfine powder package encapsulation obtained shady and cool dry place is preserved.
Embodiment 1
The Chinese medicine ultra-fine powder of the treatment yellow and white dysentery of piglet that the present embodiment provides, every 100 parts contain following component, the Radix Pulsatillae 10 parts, Rhizoma Coptidis 5 parts, Radix Scutellariae 10 parts, Cortex Phellodendri 7 parts, Cortex Fraxini 5 parts, Herba Pogostemonis 8 parts, the Radix Astragali 30 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, 15 parts, Radix Glycyrrhizae.
Embodiment 2
The Chinese medicine ultra-fine powder of the treatment yellow and white dysentery of piglet that the present embodiment provides, every 100 parts contain following component, the Radix Pulsatillae 15 parts, Rhizoma Coptidis 12 parts, Radix Scutellariae 10 parts, Cortex Phellodendri 10 parts, Cortex Fraxini 10 parts, Herba Pogostemonis 8 parts, the Radix Astragali 15 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, 10 parts, Radix Glycyrrhizae.
Embodiment 3
The Chinese medicine ultra-fine powder of the treatment yellow and white dysentery of piglet that the present embodiment provides, every 100 parts contain following component, the Radix Pulsatillae 10 parts, Rhizoma Coptidis 5 parts, Radix Scutellariae 12 parts, Cortex Phellodendri 8 parts, Cortex Fraxini 8 parts, Herba Pogostemonis 10 parts, the Radix Astragali 25 parts, the Rhizoma Atractylodis Macrocephalae 12 parts, 10 parts, Radix Glycyrrhizae.
Embodiment 4
The Chinese medicine ultra-fine powder of the treatment yellow and white dysentery of piglet that the present embodiment provides, every 100 parts contain following component, the Radix Pulsatillae 15 parts, Rhizoma Coptidis 7 parts, Radix Scutellariae 7 parts, Cortex Phellodendri 7 parts, Cortex Fraxini 5 parts, Herba Pogostemonis 12 parts, the Radix Astragali 20 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, 12 parts, Radix Glycyrrhizae.
Using method
Spice or be watered.Spice therapeutic dose be 1%(namely for need treatment situation, the dosage of Chinese medicine ultra-fine powder and the weight ratio of forage volume are 1:99), preventive dose be 0.5%(namely for need prevent situation, the dosage of Chinese medicine ultra-fine powder and the weight ratio of forage volume are 0.5:99.5); Its treatment be watered, preventive dose be spice treatment, preventive dose general, be respectively 0.25%, 0.25%; Feed 3 ~ 5 days continuously.Wherein, the many employings of control yellow scours are watered and gavage.
Animal experiment
1. choose the pig farm that 3 have HUANGBAI(sic) dysentery morbidity history, 40, each pig farm newborn piglet, be divided into 2 groups at random, feeding environment is identical, prevents with product of the present invention (the present embodiment 3).Consumption is: boiled water soaks, this product 200-250g, and wait temperature and gavage, every day 1 time, be used in conjunction 5 days, observe piglet in 30 days, result of the test is as follows:
2. choose the pig of making a definite diagnosis and occurring in HUANGBAI(sic) dysentery, it raised separately, and be divided into 3 groups at random, often organize 30,3 groups of feeding environments are identical, treat with product of the present invention (the present embodiment 3).Consumption is: boiled water soaks, this product 400-500g, and wait temperature and gavage, every day 1 time, be used in conjunction 5 days, after 5 days, viewing test result is as follows:
Show through clinical trial, medicine of the present invention, without in prevention and therapy yellow and white dysentery of piglet, all has remarkable result.
Claims (7)
1. treat a Chinese medicine ultra-fine powder for yellow and white dysentery of piglet, it is characterized in that: every 100 parts composed of the following components, Radix Pulsatillae 10-15 part, Rhizoma Coptidis 5-12 part, Radix Scutellariae 5-15 part, Cortex Phellodendri 7-15 part, Cortex Fraxini 5-10 part, Herba Pogostemonis 8-15 part, Radix Astragali 15-30 part, Rhizoma Atractylodis Macrocephalae 10-15 part, Radix Glycyrrhizae 10-15 part.
2. the Chinese medicine ultra-fine powder for the treatment of yellow and white dysentery of piglet according to claim 1, is characterized in that: every 100 parts composed of the following components, the Radix Pulsatillae 10 parts, Rhizoma Coptidis 5 parts, Radix Scutellariae 10 parts, Cortex Phellodendri 7 parts, Cortex Fraxini 5 parts, Herba Pogostemonis 8 parts, the Radix Astragali 30 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, 15 parts, Radix Glycyrrhizae.
3. the Chinese medicine ultra-fine powder for the treatment of yellow and white dysentery of piglet according to claim 1, is characterized in that: every 100 parts composed of the following components, the Radix Pulsatillae 15 parts, Rhizoma Coptidis 12 parts, Radix Scutellariae 10 parts, Cortex Phellodendri 10 parts, Cortex Fraxini 10 parts, Herba Pogostemonis 8 parts, the Radix Astragali 15 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, 10 parts, Radix Glycyrrhizae.
4. the Chinese medicine ultra-fine powder for the treatment of yellow and white dysentery of piglet according to claim 1, is characterized in that: every 100 parts composed of the following components, the Radix Pulsatillae 10 parts, Rhizoma Coptidis 5 parts, Radix Scutellariae 12 parts, Cortex Phellodendri 8 parts, Cortex Fraxini 8 parts, Herba Pogostemonis 10 parts, the Radix Astragali 25 parts, the Rhizoma Atractylodis Macrocephalae 12 parts, 10 parts, Radix Glycyrrhizae.
5. the Chinese medicine ultra-fine powder for the treatment of yellow and white dysentery of piglet according to claim 1, is characterized in that: every 100 parts composed of the following components, the Radix Pulsatillae 15 parts, Rhizoma Coptidis 7 parts, Radix Scutellariae 7 parts, Cortex Phellodendri 7 parts, Cortex Fraxini 5 parts, Herba Pogostemonis 12 parts, the Radix Astragali 20 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, 12 parts, Radix Glycyrrhizae.
6. a Chinese medicine ultra-fine powder preparation method for the arbitrary described treatment yellow and white dysentery of piglet of claim 1 to 5, is characterized in that: comprise the following steps:
A, selection, remove impurity by each raw material Radix Pulsatillae, Rhizoma Coptidis, Radix Scutellariae, Cortex Phellodendri, Cortex Fraxini, Herba Pogostemonis, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae and Radix Glycyrrhizae through selection respectively;
B, wash, put into medicine-washing machine by the medical material after selection, cleans surperficial dirt mud, dry;
C, cut medicine, the medical material dried is cut into decoction pieces through medicine cutter;
D, oven dry, drying equipment 100 ~ 105 DEG C of dryings 5 hours put into by the decoction pieces after being cut into;
E, batching, take each raw material decoction pieces after oven dry according to aforementioned proportion;
F, coarse pulverization, pulverize each raw material decoction pieces after taking through crusher for Chinese herbal medicine, and 40 mesh sieves obtain coarse powder excessively;
G, micronizing, by the coarse powder after coarse pulverization, put into super micron mill, crosses 500 mesh sieves and namely obtain superfine powder;
H, to pack, rearmounted for the superfine powder package encapsulation obtained shady and cool dry place is preserved.
7. the Chinese medicine ultra-fine powder preparation method for the treatment of yellow and white dysentery of piglet according to claim 6, is characterized in that: described drying equipment is Constant Temp. Oven.
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| CN104189373A (en) * | 2014-09-12 | 2014-12-10 | 朱凤霞 | Chinese herbal medicinal composition for preventing and controlling diarrhea of piglets |
| CN104274574B (en) * | 2014-09-28 | 2017-06-30 | 哈尔滨师范大学 | The Chinese herbal feed additive and its method of a kind of anti-chicken diarrhea |
| CN105641261A (en) * | 2014-11-11 | 2016-06-08 | 天津中敖生物科技有限公司 | Traditional Chinese medicinal composition for treating yellow scours of newborn piglets and preparation method of traditional Chinese medicinal composition |
| CN104840695A (en) * | 2015-05-18 | 2015-08-19 | 山东新希望六和集团有限公司 | Medicine combination for treating white scour of piglet and preparation method thereof |
| CN106389717A (en) * | 2015-07-21 | 2017-02-15 | 沈阳伟嘉牧业技术有限公司 | Piglet drug-resistant colibacillosis treating traditional Chinese medicine composition |
| CN109331079A (en) * | 2018-12-18 | 2019-02-15 | 河南农业大学 | Veterinary Chinese medicinal composition, veterinary drug and its preparation method and application |
| CN110507814B (en) * | 2019-10-12 | 2022-09-23 | 延边大学 | Suspension for treating yellow-white dysentery of young deer and using method thereof |
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| CN103394053A (en) * | 2013-07-18 | 2013-11-20 | 中国农业科学院兰州畜牧与兽药研究所 | Traditional Chinese medicine composition capable of preventing and treating piglet yellow and white scours as well as preparation and applications thereof |
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