CN103892843A - Non-intrusive blood glucose measurer - Google Patents
Non-intrusive blood glucose measurer Download PDFInfo
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- CN103892843A CN103892843A CN201210581150.7A CN201210581150A CN103892843A CN 103892843 A CN103892843 A CN 103892843A CN 201210581150 A CN201210581150 A CN 201210581150A CN 103892843 A CN103892843 A CN 103892843A
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Abstract
The invention relates to a non-intrusive blood glucose measurer. The non-intrusive blood glucose measure comprises a substrate, a first metal layer, a second metal layer and a glucose measuring unit. The first metal layer is formed on one side of the substrate, the second metal layer is formed on the other side of the substrate, and the glucose measuring unit is electrically connected with the first metal layer and the second metal layer and provides radio-frequency signals. By the aid of the non-intrusive blood glucose measurer, the numerical value of blood glucose in vivo can be directly measured outside the body, and inconvenience and inaccuracy in measurement by intruding the body in the prior art are avoided.
Description
Technical field
The present invention has about a kind of blood glucose sensor, relate to especially a kind of can be in the non-intrusion type blood glucose sensor of external direct sensing blood glucose value.
Background technology
Due to epoch and scientific and technological progress, modern had sizable difference with the past for diet and motor habit, and chronic disease becomes now inevasible phenomenon in civilized society, therefore health problem has received sizable concern.Diabetes in the middle of chronic disease are one of common chronic disease of compatriots, and easily cause serious complication, as retinopathy, nephropathy, hypertension, lower limb vascular obstruction etc.Although the current still radical cure method of non-diabetic, can effectively control blood sugar concentration by diet, motion and medicine.Therefore, periodic measurement blood sugar concentration is even more important, and can grasp blood sugar concentration information, and then effectively controls.
Wanting now measuring blood concentration is all that the mode (as acupuncture treatment) of invading human body is measured, pass through sampling blood, and then analyzing blood and learn blood sugar concentration, and the acupuncture treatment mode measuring blood concentration the most often using conventionally can cause fear or repel sense person to be measured, make regular check on and cannot implement, affect the monitoring of the state of an illness, or, in the time that person to be measured is had an acupuncture treatment, frightened not according to measuring regulation acupuncture treatment because of psychology, only prick near epidermis, now, just must with fashion of extrusion, blood be extruded again to the accuracy that impact is measured thus.Therefore, if can propose a kind of blood glucose measurement mode of non-intrusion type, and the fear sense of minimizing patient measuring blood certainly will be benefited to some extent the control of the glycosuria state of an illness, and can be reduced diabetic complication or fatality rate.
In view of this, the inventor of this case is according to the experience accumulation of research for many years, and arrange in pairs or groups the intention of self and constantly attempt under, and then develop a kind of a kind of non-intrusion type blood glucose sensor that can effectively improve defect mentioned in above-mentioned existing known techniques.
Summary of the invention
Main purpose of the present invention, be to provide a kind of non-intrusion type blood glucose sensor, can be directly from blood glucose numerical value in the outside sensing body of health, avoid must utilizing in existing known techniques the inaccurate of inconvenient and measurement that the mode (as: acupuncture treatment) of invading health causes.
The object of the invention to solve the technical problems realizes by the following technical solutions.A kind of non-intrusion type blood glucose of the present invention sensor comprises: substrate; The first metal layer, is formed at the one side of this substrate, and is embedded with therein at least one microstrip antenna; The second metal level, is formed at the another side of substrate, and this second metal level to have certain area not overlapping with this first metal layer, to promote wideband effect; Blood glucose sensing cell, is electrically connected at the first metal layer and this second metal level simultaneously, and radiofrequency signal can be provided.Wherein, in the time that user is put in outside the arbitrary position of human body by this non-intrusion type blood glucose sensor, this blood glucose sensing cell can provide this radiofrequency signal to the first metal layer, carries out resonance effect with blood glucose, and then calculates blood glucose value and be shown on this blood glucose sensing cell.
The object of the invention to solve the technical problems also can be applied to the following technical measures to achieve further.
Preferably, aforesaid non-intrusion type blood glucose sensor, wherein this substrate optionally uses any in following combination: polymeric substrate and ceramic substrate.
Preferably, aforesaid non-intrusion type blood glucose sensor, is wherein more optionally coated with upper conduction overlay, to increase the sensitivity of sensing on this first metal layer.
Preferably, aforesaid non-intrusion type blood glucose sensor, wherein the shape of this first metal layer and this second metal level can be made appropriate change, makes its resonant frequency between 1GHz to 8Ghz.
Preferably, aforesaid non-intrusion type blood glucose sensor, wherein by the shape that changes this first metal layer and this second metal level, and makes both on this substrate, produce nonoverlapping region and partly overlapping region, can increase strengthening wideband effect, the sensitivity while promoting sensing.
Preferably, aforesaid non-intrusion type blood glucose sensor, wherein the frequency of this radiofrequency signal is between between 1GHz to 8GHz.
The object of the invention to solve the technical problems also realizes by the following technical solutions.A kind of non-intrusion type blood glucose of the present invention sensor, it comprises: substrate; The first metal layer, is formed at the one side of this substrate, and is embedded with therein at least one microstrip antenna; The second metal level, be formed at the another side of this substrate, and the part area of this second metal level is not overlapping with this first metal layer, to promote wideband effect; Conduction overlay, is coated on the first metal layer, and this surface covered can be greater than or less than the second metal level; Blood glucose sensing cell, is electrically connected at this first metal layer and the second metal level simultaneously, and radiofrequency signal can be provided; Wherein, in the time that user is put in outside the arbitrary position of human body by this non-intrusion type blood glucose sensor, this blood glucose sensing cell can provide this radiofrequency signal to the first metal layer, carries out resonance effect with blood glucose, and then calculates blood glucose value and be shown on this blood glucose sensing cell.
The object of the invention to solve the technical problems also can be applied to the following technical measures to achieve further.
Preferably, aforesaid non-intrusion type blood glucose sensor, wherein this conduction coating layer can mix nano metal particles.
By technique scheme, non-intrusion type blood glucose sensor of the present invention at least has following advantages and beneficial effect: by the present invention can be directly from blood glucose numerical value in the outside sensing body of health, avoid must utilizing in existing known techniques the inaccurate of inconvenient and measurement that the mode (as: acupuncture treatment) of invading health causes.
Above-mentioned explanation is only the general introduction of technical solution of the present invention, in order to better understand technological means of the present invention, and can be implemented according to the content of description, and for above and other object of the present invention, feature and advantage can be become apparent, below especially exemplified by preferred embodiment, and coordinate accompanying drawing, be described in detail as follows.
Brief description of the drawings
The module diagram of Fig. 1 a kind of non-intrusion type blood glucose sensor of the present invention.
The structural representation of Fig. 2 non-intrusion type blood glucose of the present invention sensor.
The STRUCTURE DECOMPOSITION schematic diagram of Fig. 3 A, Fig. 3 B and Fig. 3 C non-intrusion type blood glucose of the present invention sensor.
The first measurement data schematic diagram of Fig. 4 non-intrusion type blood glucose of the present invention sensor.
The second measurement data schematic diagram of Fig. 5 non-intrusion type blood glucose of the present invention sensor.
The 3rd measurement data schematic diagram of Fig. 6 non-intrusion type blood glucose of the present invention sensor.
[main element symbol description]
1: substrate
2: the first metal layer
21: conduction overlay
3: the second metal levels
4: blood glucose sensing cell
Detailed description of the invention
Technological means and effect of taking for reaching predetermined goal of the invention for further setting forth the present invention, below in conjunction with accompanying drawing and preferred embodiment, to detailed description of the invention, structure, feature and effect thereof of a kind of non-intrusion type blood glucose sensor proposing according to the present invention, be described in detail as follows.
Please refer to Fig. 1, Fig. 2, Fig. 3 A, Fig. 3 B and Fig. 3 C, be respectively module diagram, structural representation and the STRUCTURE DECOMPOSITION schematic diagram of a kind of non-intrusion type blood glucose sensor of the present invention, this non-intrusion type blood glucose sensor comprises: substrate 1, the first metal layer 2, the second metal level 3, conduction overlay 21 and blood glucose sensing cell 4.
This substrate 1 optionally uses polymeric substrate and ceramic substrate; This first metal layer 2 is formed at the one side of this substrate 1, and be embedded with therein at least one microstrip antenna, in addition, this conduction overlay 21 is coated on the first metal layer 2, and optionally in conduction overlay, mix nano metal particles, to promote sensitivity and the accuracy of blood glucose sensing; This second metal level 3 is formed at the another side of substrate 1; as shown in Figure 2; on the second metal level 3, there is certain area not overlapping with this first metal layer 2; and 3 one-tenth of the second metal levels are L shaped; the first metal layer 2 is arranged at L shaped recess, and this design can effectively promote wideband effect, in like manner; the shape of the first metal layer 2 and the second metal level 3 can be done appropriate distortion, as long as have on the area covering, part is underlapped to be just encompassed in protection scope of the present invention.
Blood glucose sensing cell 4, be electrically connected at the first metal layer 2 and this second metal level 3 simultaneously, and can provide radiofrequency signal, the frequency of this radiofrequency signal is between between 1GHz to 8GHz, wherein, in the time that user is put in outside the arbitrary position of human body by this non-intrusion type blood glucose sensor, this blood glucose sensing cell 4 can provide this radiofrequency signal to the first metal layer 2, in the scope of frequency 1GHz to 8GHz, producing resonance effect with blood glucose, and then calculate blood glucose value, and be shown on this blood glucose sensing cell 4.
Above-mentionedly structure of the present invention is done to quite complete exposure, finally, to do an explanation to the precision of the measuring blood (glucose) of invention, first refer to Fig. 4, it is the first measurement data schematic diagram of non-intrusion type blood glucose sensor of the present invention, to three kinds of different concentration of glucose (Glucose 100mg/dL, Glucose 140mg/dL and Glucose 160mg/dL) under different frequencies, resonate, measured return loss (Return loss) chart, its measuring condition is that the second metal level 3 part on substrate 1 is covered to the first metal layer 2, and on it, do not there is conduction overlay, as shown in Figure 4, between frequency 1GHz to 8GHz, its maximum reflection ripple loss amplitude is reducible to be arrived-and 29db waveform separation degree is high, be easy to identification.
Referring again to Fig. 5, it is the second measurement data schematic diagram of non-intrusion type blood glucose sensor of the present invention, also equally three kinds of different concentration of glucose are resonated under different frequencies, measured return loss chart, its measuring condition is that the second metal level 3 part on substrate 1 is covered to the first metal layer 2, and on the first metal layer 2, increase conduction overlay 21, as shown in Figure 5, between frequency 1GHz to 8GHz, reducible arrive-the 31db of its maximum reflection ripple loss amplitude, and compared to the first measurement data schematic diagram, the waveform separation degree of this embodiment on drawing is higher, therefore be easy to identification.
Finally, refer to Fig. 6, it is the 3rd measurement data schematic diagram of non-intrusion type blood glucose sensor of the present invention, still equally three kinds of different concentration of glucose are resonated under different frequencies, measured return loss chart, its measuring condition is that the second metal level 3 part on substrate 1 is covered to the first metal layer 2, and mix nano metal particles in the conduction overlay 21 on the first metal layer 2, as shown in Figure 6, between frequency 1GHz to 8GHz, reducible arrive-the 32db of its maximum reflection ripple loss amplitude, although and compared to the second measurement data schematic diagram, the waveform separation degree gap of this embodiment on drawing is large, compared to first and second measurement data schematic diagram, waveform separation degree is also obviously more excellent, carry out identification therefore be easier to user.
As mentioned above, from the comparison of the enterprising row data of level of coverage, can obviously find, the return loss amplitude producing in the time partly overlapping when the first metal layer 2 and the second metal level 3 is quite large, wherein, return loss peak change is larger represents that its sensing sensitivity is higher, and under the high situation of separation degree on waveform, is easy to user and carries out identification; And it is same under the situation of part area covering, larger when being provided with conduction on the first metal layer 2 measured return loss peak change not being provided with conduction overlay when overlay, so can learn, in the time that area portions covers, the sensing sensitivity that is provided with conduction overlay can be better, in addition, relatively waveform separation degree, the design that is provided with conduction overlay is also obviously better than not being provided with the design of conduction overlay; Finally relatively the first metal layer 2 is same with the second metal level 3 is part while covering and be provided with equally conduction overlay, if be mixed with nano metal particles in conduction overlay, when return loss peak value can more not mix greatly.
Comprehensively above-mentioned, can learn the first metal layer 2 same with the second metal level 3 be part cover, and be provided with equally conduction overlay and be mixed with the nano metal particles period of the day from 11 p.m. to 1 a.m, its sensitivity and waveform separation degree are best, simple use while conducting electricity overlay taken second place, while purely only having part area covering, be the poorest, but with the present embodiment, only on area covering, do variation and can make sensing sensitivity improve significantly.
From the above, the invention has the advantages that the sensing that can carry out at human body blood glucose outward, do not need to re-use the mode that needs to invade human body in existing known techniques and just can carry out sensing, and change in area covering degree by structure and be improved the sensitivity of sensing and the identification of waveform, further, as long as repaste on metal level and be provided with conduction overlay, can make sensing sensitivity and waveform identification more promote.
The above, it is only preferred embodiment of the present invention, not the present invention is done to any pro forma restriction, although the present invention discloses as above with preferred embodiment, but not in order to limit the present invention, any those skilled in the art, do not departing within the scope of technical solution of the present invention, when can utilizing the technology contents of above-mentioned announcement to make a little change or being modified to the equivalent embodiment of equivalent variations, in every case be the content that does not depart from technical solution of the present invention, any simple modification of above embodiment being done according to technical spirit of the present invention, equivalent variations and modification, all still belong in the scope of technical solution of the present invention.
Claims (8)
1. a non-intrusion type blood glucose sensor, is characterized in that it comprises:
Substrate;
The first metal layer, is formed at the one side of this substrate, and is embedded with therein at least one microstrip antenna;
The second metal level, be formed at the another side of substrate, and the part area of this second metal level is not overlapping with this first metal layer, to promote wideband effect; And
Blood glucose sensing cell, is electrically connected at this first metal layer and the second metal level simultaneously, and radiofrequency signal can be provided;
Wherein, in the time that user is put in outside the arbitrary position of human body by this non-intrusion type blood glucose sensor, this blood glucose sensing cell can provide this radiofrequency signal to the first metal layer, carries out resonance effect with blood glucose, and then calculates blood glucose value and be shown on this blood glucose sensing cell.
2. non-intrusion type blood glucose sensor according to claim 1, is characterized in that this substrate wherein optionally uses any in following combination: polymeric substrate and ceramic substrate.
3. non-intrusion type blood glucose sensor according to claim 1, is characterized in that wherein on this first metal layer, being more optionally coated with upper conduction overlay, to increase the sensitivity of sensing.
4. non-intrusion type blood glucose sensor according to claim 1, is characterized in that wherein the shape of this first metal layer and this second metal level can be made to change, and makes its resonant frequency between 1GHz to 8Ghz.
5. non-intrusion type blood glucose sensor according to claim 1, it is characterized in that wherein by the shape that changes this first metal layer and this second metal level, and make both on this substrate, produce nonoverlapping region and partly overlapping region, can increase strengthening wideband effect, the sensitivity while promoting sensing.
6. non-intrusion type blood glucose sensor according to claim 1, is characterized in that the frequency of this radiofrequency signal is wherein between between 1GHz to 8GHz.
7. a non-intrusion type blood glucose sensor, is characterized in that it comprises:
Substrate;
The first metal layer, is formed at the one side of this substrate, and is embedded with therein at least one microstrip antenna;
The second metal level, be formed at the another side of this substrate, and the part area of this second metal level is not overlapping with this first metal layer, to promote wideband effect;
Conduction overlay, is coated on the first metal layer, and this surface covered can be greater than or less than the second metal level; And
Blood glucose sensing cell, is electrically connected at this first metal layer and the second metal level simultaneously, and radiofrequency signal can be provided;
Wherein, in the time that user is put in outside the arbitrary position of human body by this non-intrusion type blood glucose sensor, this blood glucose sensing cell can provide this radiofrequency signal to the first metal layer, carries out resonance effect with blood glucose, and then calculates blood glucose value and be shown on this blood glucose sensing cell.
8. non-intrusion type blood glucose sensor according to claim 7, is characterized in that wherein this conduction coating layer can mix nano metal particles.
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| CN201210581150.7A CN103892843A (en) | 2012-12-27 | 2012-12-27 | Non-intrusive blood glucose measurer |
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| CN201210581150.7A CN103892843A (en) | 2012-12-27 | 2012-12-27 | Non-intrusive blood glucose measurer |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107271498A (en) * | 2017-06-16 | 2017-10-20 | 哈尔滨工业大学 | Glucose quantitation test sensor and preparation method based on microwave patch resonator |
| RU207850U1 (en) * | 2021-05-21 | 2021-11-19 | Федеральное государственное автономное образовательное учреждение высшего образования «Национальный исследовательский Томский государственный университет» | SENSOR FOR NON-INVASIVE MEASUREMENT OF GLUCOSE CONCENTRATION |
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Patent Citations (7)
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107271498A (en) * | 2017-06-16 | 2017-10-20 | 哈尔滨工业大学 | Glucose quantitation test sensor and preparation method based on microwave patch resonator |
| CN107271498B (en) * | 2017-06-16 | 2019-04-23 | 哈尔滨工业大学 | Glucose quantitation test sensor and preparation method based on microwave patch resonator |
| RU207850U1 (en) * | 2021-05-21 | 2021-11-19 | Федеральное государственное автономное образовательное учреждение высшего образования «Национальный исследовательский Томский государственный университет» | SENSOR FOR NON-INVASIVE MEASUREMENT OF GLUCOSE CONCENTRATION |
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Application publication date: 20140702 |