CN103877548A - Traditional Chinese medicine preparation for treating chronic enteritis and preparation method thereof - Google Patents

Abstract

The invention discloses a traditional Chinese medicine preparation for treating chronic enteritis and a preparation method thereof. The preparation disclosed by the invention is a composition liquid preparation which is prepared by the following steps: smashing, decocting, ethanol-extracting and mixing cassia twig, codonopsis pilosula, rhizoma zingiberis, radix pseudostellariae, liquorice, elecampane, fructus aurantii, longan cores, fingered citron, endothelium corneum gigeriae galli, pericarpium citri reticulatae, agilawood, angelica sinensis, radix ophiopogonis, calcined concha arcae, scutellaria baicalensis, sargentgloryvine stems, bletilla and Chinese-dates and the like. The preparation disclosed by the invention is remarkable in effect of treating chronic enteritis. The composition obtained by drug matching and preparation method effectively achieves the function of regulating the intestinal tract and internal organs of the body by a dialectical method, and the preparation is free from toxic and side effects and stable in effect, and has the curative effect of yielding twice the result with half the effort compared with that of western medicines.

Description

A kind of Chinese medicine preparation for the treatment of chronic enteritis and preparation method thereof

Technical field

The present invention relates to a kind of Chinese medicine preparation for the treatment of enteritis, be specifically related to a kind of Chinese medicine preparation for the treatment of chronic enteritis and preparation method thereof.

Background technology

Intestinal refers to the digestive tube from stomach pylorus to anus, and intestinal is one section the longest in digestive tube, is also most important one section of function.Intestinal is the digestive organs of human body maximum, is also the toxin expelling organ of human body maximum.From physiology, anatomy, cytological angle, large intestine toxin expelling accounts for the more than 85% of human detoxification; 80% immune structure of human body is around intestinal, and endotoxic accumulation is the killer of autoimmune power.

Enteritis mainly refers to gastroenteritis, enteritis and colitis, is commonly considered as being caused by antibacterial, virus, fungus and parasite etc.That clinical main manifestations has is nauseating, vomiting, stomachache, diarrhoea, stool viscous band blood, defecate shapelessly, and part patient can have heating and tenesmus sensation.In recent years, along with the raising of people's living standard and the change of life style, the sickness rate of chronic enteritis is in rising trend, and this disease course of disease is longer, be difficult to radical cure, repeatedly outbreak, having a strong impact on people's healthy and quality of life, and canceration rate reaches 5% left and right.Although it is not very few to be used for the treatment of at present the medicine of enteritis, Western medicine is cured the symptoms, not the disease, and has used of a specified duration and has easily developed immunity to drugs, and side effect is larger, infringement liver, kidney and hemocyte, and also drug effect is unstable, easily outbreak repeatedly.

Summary of the invention

Object of the present invention is for above-mentioned deficiency, on the basis of secret prescription handed down in the family from generation to generation, in conjunction with modern Chinese and western medicine technology, a kind of Chinese medicine preparation for the treatment of chronic enteritis is provided, is to provide specifically this Chinese medicine preparation and preparation method thereof, enteritis therapeutic effect of the present invention is obvious, and nontoxic, have no side effect, effect stability, reparation technology is simple and easy to do.

Technical scheme of the present invention is as described below:

Preparation of the present invention is the composite preparation being prepared into by Ramulus Cinnamomi, Radix Codonopsis, Rhizoma Zingiberis, Radix Pseudostellariae, Radix Glycyrrhizae, the Radix Aucklandiae, Fructus Aurantii, seed of Arillus Longan, Fructus Citri Sarcodactylis, Endothelium Corneum Gigeriae Galli, Pericarpium Citri Reticulatae, Lignum Aquilariae Resinatum, Radix Angelicae Sinensis, Radix Ophiopogonis, Concha Arcae (calcined), Radix Scutellariae, Caulis Sargentodoxae, the Pseudobulbus Bletillae (Rhizoma Bletillae) and Fructus Jujubae, and wherein the quality proportioning of each component is:

Ramulus Cinnamomi 12-20g Radix Codonopsis 10-22g Rhizoma Zingiberis 8-18g

Radix Pseudostellariae 10-18g Radix Glycyrrhizae 8-15g Radix Aucklandiae 10-20g

Fructus Aurantii 8-16g seed of Arillus Longan 12-20g Fructus Citri Sarcodactylis 8-16g

Endothelium Corneum Gigeriae Galli 10-18g Pericarpium Citri Reticulatae 10-18g Lignum Aquilariae Resinatum 10-18g

Radix Angelicae Sinensis 8-15g 6-15g Radix Ophiopogonis Concha Arcae (calcined) 8-15g

Radix Scutellariae 10-18g Caulis Sargentodoxae 8-16g Pseudobulbus Bletillae (Rhizoma Bletillae) 8-15g

Fructus Jujubae 10-20g.

In order to obtain better effect, the present invention preferably raw material mass mixture ratio is:

Ramulus Cinnamomi 12-18g Radix Codonopsis 10-18g Rhizoma Zingiberis 8-12g

Radix Pseudostellariae 12-18g Radix Glycyrrhizae 8-12g Radix Aucklandiae 10-15g

Fructus Aurantii 8-12g seed of Arillus Longan 12-16g Fructus Citri Sarcodactylis 8-12g

Endothelium Corneum Gigeriae Galli 10-15g Pericarpium Citri Reticulatae 10-14g Lignum Aquilariae Resinatum 10-15g

Radix Angelicae Sinensis 8-12g 6-10g Radix Ophiopogonis Concha Arcae (calcined) 8-12g

Radix Scutellariae 10-15g Caulis Sargentodoxae 8-12g Pseudobulbus Bletillae (Rhizoma Bletillae) 8-12g

Fructus Jujubae 12-18g.

Certainly, in order to obtain further good effect, the present invention also preferably raw material mass mixture ratio be:

Ramulus Cinnamomi 15g Radix Codonopsis 12g Rhizoma Zingiberis 9g

Radix Pseudostellariae 15g Radix Glycyrrhizae 10g Radix Aucklandiae 12g

Fructus Aurantii 12g seed of Arillus Longan 10g Fructus Citri Sarcodactylis 8g

Endothelium Corneum Gigeriae Galli 12g Pericarpium Citri Reticulatae 14g Lignum Aquilariae Resinatum 12g

Radix Angelicae Sinensis 8g 8g Radix Ophiopogonis Concha Arcae (calcined) 12g

Radix Scutellariae 10g Caulis Sargentodoxae 8g Pseudobulbus Bletillae (Rhizoma Bletillae) 10g

Fructus Jujubae 15g.

The preparation method of above-mentioned treatment chronic enteritis Chinese medicine preparation, comprises the steps:

1), Radix Codonopsis put into pannikin carry out stir-fry dish cooked in a small wok, meaning the food is prepared with special care to surperficial micro-Jiao, then pulverize and cross 80 mesh sieves through pulverizer, for subsequent use;

2), Ramulus Cinnamomi, Rhizoma Zingiberis, Radix Pseudostellariae, Radix Glycyrrhizae, Fructus Aurantii, seed of Arillus Longan, Fructus Citri Sarcodactylis, Fructus Jujubae, Radix Scutellariae, Caulis Sargentodoxae are prepared in proportion, be ground into powder and cross 90 mesh sieves through pulverizer, naturally drying, for subsequent use;

3), by step 1) and 2) in each component powders mix, add pure water to decoct twice, add for the first time 10 times of pure water to decoct 1 hour, extract filtrate for later use; Add for the second time 6 times of pure water to decoct half an hour, then collecting decoction filtration, for subsequent use;

4), the remaining Radix Aucklandiae, Endothelium Corneum Gigeriae Galli, Pericarpium Citri Reticulatae, Lignum Aquilariae Resinatum, Radix Angelicae Sinensis, Radix Ophiopogonis, Concha Arcae (calcined), the Pseudobulbus Bletillae (Rhizoma Bletillae) are prepared in proportion, be ground into powder and cross 80 mesh sieves through pulverizer, naturally drying, for subsequent use;

5), each component powders in step 4) is mixed, add the ethanol of 4～6 times 70%～80%, reflux 3～5 hours, extracts to filter and obtains filtrate; Then in remaining medicinal residues, again add the ethanol of 2～4 times 65%～75%, reflux 2～3 hours, extracts and filters acquisition filtrate; The filtrate of twice acquisition is combined, and concentrating under reduced pressure is removed alcohol solvent, dry, obtains and gets dry extract;

6), by above-mentioned steps 5) in the dry cream that obtains carry out micronizing powdered and cross 200 mesh sieves, then powder is added to 3) collecting decoction in step, mix and shake up and can make.

The above-mentioned Chinese medicine composition pharmaceutical solutions of producing can be for oral, if can each also long-term drink, better effects if of drinking in right amount once of morning, noon and afternoon.

Theoretical foundation of the present invention is:

Ramulus Cinnamomi, is the dry twig of Lauraceae aiphyllium plant Cortex Cinnamomi, main product in Guangxi, the ground such as Guangdong and Yunnan.Spring, summer are cut twig, dry or dry in the shade, and thinly slice or segment use.Row acrid in the mouth temperature, has warming the meridian and promoting blood circulation, the effect of expelling cold and relieving exterior syndrome, and the qi stagnation hemagglutination that causes for the treatment of YANG QI deficiency, coldness and pain in the epigastrium, the diseases such as cold in blood amenorrhea, also can treat the anemofrigid cold causing because catching a cold, watery nasal discharge cough etc., and disease has good effect.Ramulus Cinnamomi ethanol extract can suppress escherichia coli, bacillus subtilis and staphylococcus aureus in vitro, and valid density is 25 mg/ml or following; Staphylococcus albus, dysentery bacterium, Typhoid and paratyphoid first bacillus, streptococcus pneumoniae, aerobacteria, Bacillus proteus, anthrax bacillus, Salmonella enteritidis, vibrio cholera etc. are also had to inhibitory action.

Radix Codonopsis, has anti-mucous membrane to the intestines and stomach effect, and invigorating the spleen and replenishing QI, the pharmacological action that spleen invigorating effect is relevant are adjustment gastrointestinal motility function, antiulcer.There is enhancing human body immunity function, strengthen hemopoietic function, anti-stress, heart tonifying, shock, adjusting blood pressure, resist myocardial ischemia and the effect such as anticoagulant.Radix Codonopsis also has the effects such as Fructus Alpiniae Oxyphyllae, calmness, hypnosis, convulsion.Radix Codonopsis has invigorating the spleen and replenishing QI, effect of spleen invigorating lung benefiting.Be used for deficiency of the spleen and lung etc.

Rhizoma Zingiberis, is the dry product of Rhizoma Zingiberis Recens, and acrid in the mouth is hot in nature, returns spleen, stomach, the heart, lung meridian.Have warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, and interior cold syndrome appears in effect of warming the lung to resolve fluid-retention for YANG deficiency of the spleen and stomach, and disease sees that food stagnation does not disappear, and vomiting clear water, defecates rare, abdomen cold type of pain, pale tongue with white fur, deep-thready pulse etc.

Radix Pseudostellariae, Radix Pseudostellariae is called again virgin ginseng, is the one of Radix Ginseng, and the property of medicine is gentle, sweet in the mouth, has the effect of tonifying QI to produce body fluid, is usually used in weakness of the spleen and stomach, deficiency of stomach-Yin, fatigue and weakness, dyspepsia, inappetence etc.

Radix Glycyrrhizae, is a kind of tonification Chinese herbal medicine, and medicinal part is root and rhizome, and Medicinal Materials Characters root is cylindrical, has invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the effect of coordinating the actions of various ingredients in a prescription; For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.

The Radix Aucklandiae, is the common name of feverfew Saussurea lappa Clarke and Radix Vladimiriae, is the dry root of the feverfew Radix Aucklandiae.The Radix Aucklandiae has antibacterial action, can suppress the regeneration of gastrointestinal antibacterial, can also suppress the breeding copying of liver virus, plays the effect of antiinflammatory hepatoprotective.

Fructus Aurantii, nature and flavor toil, cool, enters lung, spleen, large intestine channel, has dispelling the stagnated QI, row expectorant, removing food stagnancy, control that chest and diaphragm expectorant is stagnant, the feeling of stuffiness in chest, the side of body is swollen, heavy after food, eructation, vomiting, dysentery, proctoptosis, the effects such as uterine prolapse.

Seed of Arillus Longan, puckery, has the effects such as regulating QI to relieve pain, hemostasis, removing dampness, can be used for hernia pain, traumatic hemorrhage, scabies, eczema etc.Loose ailment said due to cold or exposure wind, controls the dizziness of having a guilty conscience, deafness, dim eyesight.The kidney warming diuresis, hemostasis, analgesic therapy, regulates the flow of vital energy, removing dampness; Cure mainly the dirty pathogen of protium, control anorexia, inappetence, drive intestinal leaf parasite and schistosomicide.Long-term edible, strong physique, life lengthening, the long wisdom of nourishing the brain and tranquilizing the mind, appetite promoting and the spleen strengthening, complement void.

Fructus Citri Sarcodactylis, have another name called the five fingers Fructus Citri tangerinae, Fructus Citri Sarcodactylis, its root, stem, leaf, flower, fruit all can be used as medicine, and bitter in the mouth, pungent, sweet, warm, enters liver, spleen, stomach, lung meridian, there is activating QI to eliminate phlegm, the multiple medicinal functions such as cough-relieving relieving distension, the liver soothing and the spleen invigorating and gastrointestinal, have effect of dispersing the stagnated live-QI to relieve the stagnation of QI, drying dampness to eliminate phlegm, regulating the flow of Qi and the middle Jiao, are usually used in stagnation of QI due to depression of the liver, stagnation of QI in spleen and stomach and phlegm-damp and stop up the diseases such as lung.

Endothelium Corneum Gigeriae Galli, sweet in the mouth is flat, enters taste urinary bladder channel, containing gastric hormone, micro-pepsin, amylase, multivitamin, have the gastric secretion of increasing and gastro-intestinal digestion ability, the effects such as the rate of evacuation of accelerate gastrointestinal, have invigorating the stomach and promoting digestion, the function that controlling nocturnal emission with astringent drugs is only lost, fossil is treating stranguria, and energy invigorating the spleen and stomach, can control eating accumulation, is the good medicine of invigorating the stomach and promoting digestion.

Pericarpium Citri Reticulatae, another name Lignum Aquilariae Resinatum, acrid in the mouth, hardship, warm in nature; Return spleen, stomach, lung meridian; Fragrant a surname is loose for gas, can rise and can fall; The bitter substance of Pericarpium Citri Reticulatae is take limonin and bitter principle as representative " limonoid ", and this limonoid taste is gentle, soluble in water, contributes to the digestion of food; There is regulating the flow of Qi and the middle Jiao, drying dampness to eliminate phlegm, effect of diuretic relieving constipation.Cure mainly the tired disease such as unable of incoordination between the spleen and stomach, abdominal distention, weakness of the spleen and stomach, inappetence, vomiting hiccup, limb, and Radix Codonopsis, Rhizoma Zingiberis, Rhizoma Dioscoreae be equal to use, effect is better.

Lignum Aquilariae Resinatum, nature and flavor are pungent, bitter, and tepor is returned spleen, stomach, kidney channel, has promoting the circulation of QI to relieve pain, warming middle-JIAO to arrest vomiting, the effects such as warming the kidney improving inspiration by invigorating kidney-QI, cure mainly vomiting singultus, abdominal distention, waist knee joint cold caused by deficiency, large intestine constipation due to insufficiency, the vexed pain of breast abdominal distention, gastrofrigid vomiting singultus, the QI rising in reverse order of suffering from a deficiency of the kidney dyspnea with rapid respiration etc.

Radix Angelicae Sinensis, herbaceos perennial, is distributed in the ground such as Gansu, Yunnan, Sichuan, Qinghai, Shaanxi, Hunan, Hubei, Guizhou, and all there is cultivation various places.The root of Radix Angelicae Sinensis can be used as medicine, and is one of the most frequently used Chinese medicine.Radix Angelicae Sinensis has effect of promoting the flow of QI-blood by warming the meridian, promoting blood circulation and stopping pain, and no matter asthenia cold abdominalgia, or Fengshi Guanjie pain, or traumatic injury stagnation of blood stasis pain, all can use Radix Angelicae Sinensis.Radix Angelicae Sinensis is also usually used in ulcer sores.Because Radix Angelicae Sinensis blood circulation promoting and blood stasis dispelling, can play effect of reducing swelling and alleviating pain, evacuation of pus granulation promoting.The recipe Xian fang Huoming Yin for the treatment of skin infection, is just equal to use with Radix Angelicae Sinensis and Radix Paeoniae Rubra, Flos Lonicerae, stir-baked SQUAMA MANITIS.

Radix Ophiopogonis, is Liliaceae Ophiopogon perennial evergreen herbaceous plant, and fibrous root is more sturdy, and often expand at the top of root or middle part becomes spindle shape meat fritter, is used as medicine with tuber.Cold nature, sweet and slightly bitter taste, pharmacological evaluation proves, and Radix Ophiopogonis has leukocyte increasing, extends the effect of antibody life period, improves immunologic function and nucleic acid synthetic ratio, and the immune materials such as enhancing antibody, complement, interferon, lysozyme produce.Therefore there is the healthy energy of enhancing Radix Ophiopogonis, strengthen anti-evil effect, thereby reduce the generation of disease.For the disease such as palpitation and being susceptible to fright and calentura later stage consumption of body fluid by heat of few thirsty, the dry cough spitting of blood in Tianjin of lung-stomach yin deficiency, insufficiency of heart-YIN.

Concha Arcae (calcined), sweet in the mouth, property are put down, and return liver, lung, stomach warp.There is expectorant blood stasis dispelling, hard masses softening and resolving, effect of relieving gastric hyperacidity to alleviate stomachache.Be mainly used in the pantothenic acid of having a stomachache, the long-pending knot of pertinacious phlegm, thickness difficulty such as coughs up at the disease.

Radix Scutellariae, Radix Scutellariae another name Radix Scutellariae, tsuchikane tea root.For labiate, be used as medicine with root.Have heat clearing and damp drying, removing heat from blood is antiabortive, detoxicating functions.Cure mainly the diseases such as epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, conjunctival congestion, frequent fetal movement, hypertension, carbuncle furuncle.The clinical practice of Radix Scutellariae is antibacterial not worse than Rhizoma Coptidis, and does not develop immunity to drugs.

Caulis Sargentodoxae, bitter in the mouth is flat.Return large intestine, Liver Channel.Function cures mainly: heat-clearing and toxic substances removing, invigorate blood circulation, and dispel the wind.For abdominalgia with intestinal abscess, amenorrhea dysmenorrhea, rheumatic arthralgia, tumbling and swelling.There is the eliminating carbuncle of relieving internal heat, promoting blood circulation to remove obstruction in the collateral, the effect of wind dispelling insecticide.Control acute and chronic appendicitis, rheumatic arthralgia, bloody dysentery, stranguria with blood, menoxenia, infantile malnutrition, worm pain, the diseases such as injury from falling down.

The Pseudobulbus Bletillae (Rhizoma Bletillae), cold in nature, bitter in the mouth, sweet, puckery, nontoxic; Return lung, stomach, Liver Channel.There is astringing to arrest bleeding, the function of detumescence and promoting granulation.Cure mainly slightly blood of pulmonary tuberculosis, spit blood, epistaxis, has blood in stool, traumatic hemorrhage, carbuncle pyogenic infections from tumour or sore, scrofula, anal fistula, burn and scald, rhagadia manus et pedis, the diseases such as anal fissure.With other drug matchings of the present invention, treatment enteritis successful.

Fructus Jujubae, sweet in the mouth is warm in nature, returns taste warp, the nutritional labelings such as rich in proteins, fat, saccharide, carotene, vitamin B group, vitamin C, Citrin and calcium, phosphorus, ferrum and cyclic adenosine monophosphate.Wherein ascorbic content comes out at the top in fruit, has vitamin king's laudatory title.There is invigorating the spleen and replenishing QI, invigorating spleen and reinforcing stomach, nourishing blood to tranquillize the mind, effect of the mitigation property of medicine.For insufficiency of the spleen lack of appetite, weak loose stool, woman hysteria.

From China's Traditional Chinese Medicine angle, the etiology and pathogenesis of chronic enteritis, there is eating and drinking without temperance, kill damaging the spleen and stomach state, or invade in exopathogen, undermine taste, or suffering is disgruntled, the liver failing to maintain the normal flow of QI, perverse and unreasonable manner is violated stomach, and innate deficiency, the situations such as weakness of the spleen and stomach, its sick table is at " intestinal ", but with " stomach ", " spleen ", " liver ", " kidney " is in close relations, pathogenic characteristic is deficiency complicated with excess, therefore the compositions obtaining by the above-mentioned drug matching of the present invention and preparation method, adopt dialectical method effectively to reach effect of conditioning intestinal and the vital organs of the human body, have no side effect, effect stability, reach the curative effect of getting twice the result with half the effort compared with Western medicine.

clinical experiment 1:

1), observing time: in the situation that technical solution of the present invention does not disclose, select in April, 2012 to 2012 year JIUYUE 6 months.

2), the object of observation: select 10 routine chronic enteritis cases in Shenzhen City, Guangdong Province Gastroenterology dept. of institute of traditional Chinese medicine: male 4 examples, female's 6 examples; Age: 40-55 years old 5 example, 60-75 years old 5 example; Occupation: common working clan's 5 examples, retired person 5 examples.Disease: repeatedly stomachache, the abdominal distention of outbreak, suffer from diarrhoea, rush down lower mucus or bloody purulent stool, stage of attack, defecate more than 3 times/day, companion's defecation is not freely or tenesmus; Tongue fur is how yellow greasy or greasy in vain; All disease is just all made a definite diagnosis through fibercolonscopy.

3), using method: preparation oral liquid of the present invention is being taken after the meal half an hour, and every day 3 times, each 200ml, 2 months was 1 course for the treatment of, and 3 courses for the treatment of are as observation of curative effect.

4), observing effect:

Taking continuously after 3 courses for the treatment of, clinical symptoms, sign disappear, fibro-colonoscope check is normal, and intestinal mucosa pathological changes is recovered normal 5 examples, and clinical symptoms obviously alleviates, sign disappears substantially, fibro-colonoscope check takes a turn for the better, 3 examples that intestinal mucosa pathological changes is obviously improved, and before and after treatment, clinical symptoms and sign are without improvement, fibro-colonoscope check is without 2 examples that take a turn for the better, total effective rate 80%.

clinical experiment 2 :

1), observing time: in the situation that technical solution of the present invention does not disclose, select 6 months of year July in February, 2013 to 2013.

2), the object of observation: 20 routine cases are selected by Gastroenterology dept. of institute of traditional Chinese medicine in Futian District, Shenzhen City, Guangdong Province: male 13 examples, female's 7 examples; Age: 32-55 years old 10 example, 56-75 years old 10 example; Occupation: post civil servant 10 examples that once assumed the leadership, common teachers 10 examples.Disease: repeatedly stomachache, the abdominal distention of outbreak, suffer from diarrhoea, rush down lower mucus or bloody purulent stool, stage of attack, defecate more than 3 times/day, companion's defecation is not freely or tenesmus; Tongue fur is how yellow greasy or greasy in vain; All disease is just all made a definite diagnosis through fibercolonscopy.

3), using method: preparation oral liquid of the present invention is being taken after the meal half an hour, and every day 3 times, each 200ml, 2 months was 1 course for the treatment of, and 3 courses for the treatment of are as observation of curative effect.

4), observing effect:

Taking continuously after 3 courses for the treatment of, clinical symptoms, sign disappear, fibro-colonoscope check is normal, and intestinal mucosa pathological changes is recovered normal 14 examples, and clinical symptoms obviously alleviates, sign disappears substantially, fibro-colonoscope check takes a turn for the better, 1 example that intestinal mucosa pathological changes is obviously improved, and before and after treatment, clinical symptoms and sign are without improvement, fibro-colonoscope check is without 5 examples that take a turn for the better, total effective rate 75%.

clinical experiment 3 :

1), observing time: in the situation that technical solution of the present invention does not disclose, select 6 months of year January in August, 2013 to 2014.

2), the object of observation: select 30 routine cases in Gastroenterology dept. of Song Gang the People's Hospital, Shenzhen City, Guangdong Province: male 15 examples, female's 15 examples; Age: 35-55 years old 16 example, 60-75 years old 14 example; Occupation: the common master of private enterprise 14 examples, common retired professor's 16 examples.Disease: repeatedly stomachache, the abdominal distention of outbreak, suffer from diarrhoea, rush down lower mucus or bloody purulent stool, stage of attack, defecate more than 3 times/day, companion's defecation is not freely or tenesmus; Tongue fur is how yellow greasy or greasy in vain; All disease is just all made a definite diagnosis through fibercolonscopy.

3), using method: preparation oral liquid of the present invention is being taken after the meal half an hour, and every day 3 times, each 200ml, 2 months was 1 course for the treatment of, and 3 courses for the treatment of are as observation of curative effect.

4), observing effect:

Taking continuously after 3 courses for the treatment of, clinical symptoms, sign disappear, fibro-colonoscope check is normal, and intestinal mucosa pathological changes is recovered normal 19 examples, and clinical symptoms obviously alleviates, sign disappears substantially, fibro-colonoscope check takes a turn for the better, 5 examples that intestinal mucosa pathological changes is obviously improved, and before and after treatment, clinical symptoms and sign are without improvement, fibro-colonoscope check is without 6 examples that take a turn for the better, total effective rate 80%.

In conjunction with above clinical data and theoretical foundation of the present invention, visible beneficial effect of the present invention is, the preparation that the present invention makes has good result for treatment chronic enteritis, and nontoxic, have no side effect, and effect stability, reparation technology is simple and easy to do.

The specific embodiment

Below in conjunction with embodiment, the present invention is explained detailedly:

embodiment 1:

Preparation of the present invention is the composite preparation being prepared into by Ramulus Cinnamomi, Radix Codonopsis, Rhizoma Zingiberis, Radix Pseudostellariae, Radix Glycyrrhizae, the Radix Aucklandiae, Fructus Aurantii, seed of Arillus Longan, Fructus Citri Sarcodactylis, Endothelium Corneum Gigeriae Galli, Pericarpium Citri Reticulatae, Lignum Aquilariae Resinatum, Radix Angelicae Sinensis, Radix Ophiopogonis, Concha Arcae (calcined), Radix Scutellariae, Caulis Sargentodoxae, the Pseudobulbus Bletillae (Rhizoma Bletillae) and Fructus Jujubae, and wherein the quality proportioning of each component is:

Ramulus Cinnamomi 12g Radix Codonopsis 10g Rhizoma Zingiberis 10g

Radix Pseudostellariae 12g Radix Glycyrrhizae 12g Radix Aucklandiae 15g

Fructus Aurantii 10g seed of Arillus Longan 12g Fructus Citri Sarcodactylis 8g

Endothelium Corneum Gigeriae Galli 15g Pericarpium Citri Reticulatae 15g Lignum Aquilariae Resinatum 13g

Radix Angelicae Sinensis 12g 8g Radix Ophiopogonis Concha Arcae (calcined) 10g

Radix Scutellariae 12g Caulis Sargentodoxae 13g Pseudobulbus Bletillae (Rhizoma Bletillae) 10g

Fructus Jujubae 16g.

The preparation method of above-mentioned treatment chronic enteritis Chinese medicine preparation, comprises the steps:

1), Radix Codonopsis put into pannikin carry out stir-fry dish cooked in a small wok, meaning the food is prepared with special care to surperficial micro-Jiao, then pulverize and cross 80 mesh sieves through pulverizer, for subsequent use;

2), Ramulus Cinnamomi, Rhizoma Zingiberis, Radix Pseudostellariae, Radix Glycyrrhizae, Fructus Aurantii, seed of Arillus Longan, Fructus Citri Sarcodactylis, Fructus Jujubae, Radix Scutellariae, Caulis Sargentodoxae are prepared in proportion, be ground into powder and cross 90 mesh sieves through pulverizer, naturally drying, for subsequent use;

3), by step 1) and 2) in each component powders mix, add pure water to decoct twice, add for the first time the little fire of 8 times of pure water to decoct 1 hour, add for the second time 4 times of little fire of pure water to decoct half an hour, then collecting decoction filtering, for subsequent use;

4), the remaining Radix Aucklandiae, Endothelium Corneum Gigeriae Galli, Pericarpium Citri Reticulatae, Lignum Aquilariae Resinatum, Radix Angelicae Sinensis, Radix Ophiopogonis, Concha Arcae (calcined), the Pseudobulbus Bletillae (Rhizoma Bletillae) are prepared in proportion, be ground into powder and cross 80 mesh sieves through pulverizer, naturally drying, for subsequent use;

5), each component powders in step 4) is mixed, add the ethanol of 4～6 times 70%～80%, reflux 3～5 hours, extracts to filter and obtains filtrate; Then in remaining medicinal residues, again add the ethanol of 2～4 times 65%～75%, reflux 2～3 hours, extracts and filters acquisition filtrate; The filtrate of twice acquisition is combined, and concentrating under reduced pressure is removed alcohol solvent, dry, obtains and gets dry extract;

6), by above-mentioned steps 5) in obtain dry cream carry out micronizing powdered and cross 200 mesh sieves, then powder is added to the collecting decoction in step 3), mix shake up and can make.

The above-mentioned Chinese medicine composition pharmaceutical solutions of producing can be for oral, if can respectively drink once and long-term drink better effects if the morning, noon and afternoon.

embodiment 2:

The present invention also preferably raw materials quality be (gram):

Ramulus Cinnamomi 12g Radix Codonopsis 10g Rhizoma Zingiberis 10g

Radix Pseudostellariae 12g Radix Glycyrrhizae 12g Radix Aucklandiae 15g

Fructus Aurantii 10g seed of Arillus Longan 12g Fructus Citri Sarcodactylis 8g

Endothelium Corneum Gigeriae Galli 15g Pericarpium Citri Reticulatae 10g Lignum Aquilariae Resinatum 13g

Radix Angelicae Sinensis 12g 8g Radix Ophiopogonis Concha Arcae (calcined) 10g

Radix Scutellariae 12g Caulis Sargentodoxae 13g Pseudobulbus Bletillae (Rhizoma Bletillae) 10g

Fructus Jujubae 16g.

Preparation method is as embodiment 1.

embodiment 3:

The present invention also preferably raw materials quality be (gram):

Ramulus Cinnamomi 15g Radix Codonopsis 12g Rhizoma Zingiberis 9g

Radix Pseudostellariae 15g Radix Glycyrrhizae 10g Radix Aucklandiae 12g

Fructus Aurantii 12g seed of Arillus Longan 10g Fructus Citri Sarcodactylis 8g

Endothelium Corneum Gigeriae Galli 12g Pericarpium Citri Reticulatae 14g Lignum Aquilariae Resinatum 12g

Radix Angelicae Sinensis 8g 8g Radix Ophiopogonis Concha Arcae (calcined) 12g

Radix Scutellariae 10g Caulis Sargentodoxae 8g Pseudobulbus Bletillae (Rhizoma Bletillae) 10g

Fructus Jujubae 15g.

Preparation method is as embodiment 1.

embodiment 4:

The present invention also preferably raw materials quality be (gram):

Ramulus Cinnamomi 18g Radix Codonopsis 15g Rhizoma Zingiberis 12g

Radix Pseudostellariae 16g Radix Glycyrrhizae 12g Radix Aucklandiae 15g

Fructus Aurantii 13g seed of Arillus Longan 15g Fructus Citri Sarcodactylis 12g

Endothelium Corneum Gigeriae Galli 16g Pericarpium Citri Reticulatae 14g Lignum Aquilariae Resinatum 16g

Radix Angelicae Sinensis 10g 12g Radix Ophiopogonis Concha Arcae (calcined) 15g

Radix Scutellariae 16g Caulis Sargentodoxae 13g Pseudobulbus Bletillae (Rhizoma Bletillae) 12g

Fructus Jujubae 18g.

Preparation method is as embodiment 1.

embodiment 5 :

The present invention also preferably raw materials quality be (gram):

Ramulus Cinnamomi 16g Radix Codonopsis 18g Rhizoma Zingiberis 15g

Radix Pseudostellariae 14g Radix Glycyrrhizae 15g Radix Aucklandiae 18g

Fructus Aurantii 15g seed of Arillus Longan 18g Fructus Citri Sarcodactylis 14g

Endothelium Corneum Gigeriae Galli 18g Pericarpium Citri Reticulatae 16g Lignum Aquilariae Resinatum 14g

Radix Angelicae Sinensis 12g 13g Radix Ophiopogonis Concha Arcae (calcined) 13g

Radix Scutellariae 18g Caulis Sargentodoxae 15g Pseudobulbus Bletillae (Rhizoma Bletillae) 15g

Fructus Jujubae 18g.

Preparation method is as embodiment 1.

embodiment 6 :

The present invention also preferably raw materials quality be (gram):

Ramulus Cinnamomi 15g Radix Codonopsis 18g Rhizoma Zingiberis 15g

Radix Pseudostellariae 16g Radix Glycyrrhizae 15g Radix Aucklandiae 20g

Fructus Aurantii 12g seed of Arillus Longan 20g Fructus Citri Sarcodactylis 16g

Endothelium Corneum Gigeriae Galli 16g Pericarpium Citri Reticulatae 18g Lignum Aquilariae Resinatum 15g

Radix Angelicae Sinensis 15g 15g Radix Ophiopogonis Concha Arcae (calcined) 12g

Radix Scutellariae 16g Caulis Sargentodoxae 16g Pseudobulbus Bletillae (Rhizoma Bletillae) 13g

Fructus Jujubae 20g.

Preparation method is as embodiment 1.

Above-described embodiment is only the several of the numerous embodiments of the present invention, and as each formula strengthened in the ratio in technical scheme or reducing dose, this treatment chronic enteritis preparation curative effect making is also unaffected, within also will dropping on the scope of the present invention.

Claims (4)

1. treat the Chinese medicine preparation of chronic enteritis for one kind, it is characterized in that, preparation of the present invention is the composite preparation being prepared into by Ramulus Cinnamomi, Radix Codonopsis, Rhizoma Zingiberis, Radix Pseudostellariae, Radix Glycyrrhizae, the Radix Aucklandiae, Fructus Aurantii, seed of Arillus Longan, Fructus Citri Sarcodactylis, Endothelium Corneum Gigeriae Galli, Pericarpium Citri Reticulatae, Lignum Aquilariae Resinatum, Radix Angelicae Sinensis, Radix Ophiopogonis, Concha Arcae (calcined), Radix Scutellariae, Caulis Sargentodoxae, the Pseudobulbus Bletillae (Rhizoma Bletillae) and Fructus Jujubae, and wherein the quality proportioning of each component is:

Ramulus Cinnamomi 12-20g Radix Codonopsis 10-22g Rhizoma Zingiberis 8-18g

Radix Pseudostellariae 10-18g Radix Glycyrrhizae 8-15g Radix Aucklandiae 10-20g

Fructus Aurantii 8-16g seed of Arillus Longan 12-20g Fructus Citri Sarcodactylis 8-16g

Endothelium Corneum Gigeriae Galli 10-18g Pericarpium Citri Reticulatae 10-18g Lignum Aquilariae Resinatum 10-18g

Radix Angelicae Sinensis 8-15g 6-15g Radix Ophiopogonis Concha Arcae (calcined) 8-15g

Radix Scutellariae 10-18g Caulis Sargentodoxae 8-16g Pseudobulbus Bletillae (Rhizoma Bletillae) 8-15g

Fructus Jujubae 10-20g.

2. the Chinese medicine preparation for the treatment of chronic enteritis according to claim 1, is further characterized in that, wherein the quality proportioning of each component is:

Ramulus Cinnamomi 12-18g Radix Codonopsis 10-18g Rhizoma Zingiberis 8-12g

Radix Pseudostellariae 12-18g Radix Glycyrrhizae 8-12g Radix Aucklandiae 10-15g

Fructus Aurantii 8-12g seed of Arillus Longan 12-16g Fructus Citri Sarcodactylis 8-12g

Endothelium Corneum Gigeriae Galli 10-15g Pericarpium Citri Reticulatae 10-14g Lignum Aquilariae Resinatum 10-15g

Radix Angelicae Sinensis 8-12g 6-10g Radix Ophiopogonis Concha Arcae (calcined) 8-12g

Radix Scutellariae 10-15g Caulis Sargentodoxae 8-12g Pseudobulbus Bletillae (Rhizoma Bletillae) 8-12g

Fructus Jujubae 12-18g.

3. the Chinese medicine preparation for the treatment of chronic enteritis according to claim 1 and 2, is further characterized in that, wherein the quality proportioning of each component is:

Ramulus Cinnamomi 15g Radix Codonopsis 12g Rhizoma Zingiberis 9g

Radix Pseudostellariae 15g Radix Glycyrrhizae 10g Radix Aucklandiae 12g

Fructus Aurantii 12g seed of Arillus Longan 10g Fructus Citri Sarcodactylis 8g

Endothelium Corneum Gigeriae Galli 12g Pericarpium Citri Reticulatae 14g Lignum Aquilariae Resinatum 12g

Radix Angelicae Sinensis 8g 8g Radix Ophiopogonis Concha Arcae (calcined) 12g

Radix Scutellariae 10g Caulis Sargentodoxae 8g Pseudobulbus Bletillae (Rhizoma Bletillae) 10g

Fructus Jujubae 15g.

4. a preparation method for the treatment of the Chinese medicine preparation of chronic enteritis, is characterized in that, it comprises the steps:

1), Radix Codonopsis put into pannikin carry out stir-fry dish cooked in a small wok, meaning the food is prepared with special care to surperficial micro-Jiao, then pulverize and cross 80 mesh sieves through pulverizer, for subsequent use;

2), Ramulus Cinnamomi, Rhizoma Zingiberis, Radix Pseudostellariae, Radix Glycyrrhizae, Fructus Aurantii, seed of Arillus Longan, Fructus Citri Sarcodactylis, Fructus Jujubae, Radix Scutellariae, Caulis Sargentodoxae are prepared in proportion, be ground into powder and cross 90 mesh sieves through pulverizer, naturally drying, for subsequent use;

3), by step 1) and 2) in each component powders mix, add pure water to decoct twice, add for the first time the little fire of 10 times of pure water to decoct 1 hour, extract filtrate for later use, add for the second time 6 times of little fire of pure water to decoct half an hour, then collecting decoction filtration, for subsequent use;

4), the remaining Radix Aucklandiae, Endothelium Corneum Gigeriae Galli, Pericarpium Citri Reticulatae, Lignum Aquilariae Resinatum, Radix Angelicae Sinensis, Radix Ophiopogonis, Concha Arcae (calcined), the Pseudobulbus Bletillae (Rhizoma Bletillae) are prepared in proportion, be ground into powder and cross 80 mesh sieves through pulverizer, naturally drying, for subsequent use;

5), each component powders in step 4) is mixed, add the ethanol of 4～6 times 70%～80%, reflux 3～5 hours, extracts to filter and obtains filtrate; Then in remaining medicinal residues, again add the ethanol of 2～4 times 65%～75%, reflux 2～3 hours, extracts and filters acquisition filtrate; The filtrate of twice acquisition is combined, and concentrating under reduced pressure is removed alcohol solvent, dry, obtains and gets dry extract;

6), by above-mentioned steps 5) in obtain dry cream carry out micronizing powdered and cross 200 mesh sieves, then powder is added to the collecting decoction in step 3), mix shake up and can make,

The above-mentioned Chinese medicine composition pharmaceutical solutions of producing can be for oral, if can each also long-term drink, better effects if of drinking in right amount once of morning, noon and afternoon.