CN103861132A - Plasma and plasma product virus inactivation device - Google Patents
Plasma and plasma product virus inactivation device Download PDFInfo
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- CN103861132A CN103861132A CN201210549988.8A CN201210549988A CN103861132A CN 103861132 A CN103861132 A CN 103861132A CN 201210549988 A CN201210549988 A CN 201210549988A CN 103861132 A CN103861132 A CN 103861132A
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Abstract
The invention provides a plasma and plasma product virus inactivation device, comprising a bottle stopper puncture device, a blood filtering screen, a flow stopping clamp, a photosensitizer (methylene blue), an illumination bag, an adsorption filter, a plasma storage bag and an infusion hose, wherein the bottle stopper puncture device is positioned at the top end of the device; the blood filtering screen is positioned between the bottle stopper puncture device and the illumination bag; the illumination bag is positioned between the blood filtering screen and the adsorption filter; the adsorption filter is positioned between the illumination bag and the plasma storage bag; the plasma storage bag is positioned at the lower end of the device; and the components are communicated by the infusion hose, and the photosensitizer is directly added in the illumination bag. The plasma and plasma product virus inactivation device is additionally provided with the blood filtering screen, and coagulum in plasma can be removed and prevented from blocking the adsorption filter, so that the plasma and plasma product virus inactivation device can be used for performing virus inactivation on both fresh plasma and stocked serums; by directly adding the photosensitizer into the illumination bag, a photosensitizer adding component is omitted, so that the inactivation device is simple in structure, convenient in operation and low in cost.
Description
Technical field
the present invention is the inactivating device of clinical infusion blood plasma and blood plasma product virus.
Background technology
blood-plasma virus killing apparatus of the prior art (CN1249952A), mainly comprise that blood taking needle, blood taking bag, the first transfering bag, photosensitizer add assembly, fluorescence irradiation bag, adsorption filter and blood plasma reservoir bag, in prior art, the input of fluorescence irradiation bag and outfan are all arranged on the same side of fluorescence irradiation bag, photosensitizer is added in photosensitizer to be added in assembly, when use, plasma flow is added assembly through photosensitizer, and flows in fluorescence irradiation bag with together with photosensitizer wherein.Virus inactivating device of the prior art can only the fresh collection of deactivation blood plasma, in the time wanting deactivation to deposit the blood plasma of certain hour, photosensitizer adds assembly and is just easily stopped up by the condensation product in blood plasma, blood plasma cannot add assembly by photosensitizer, cause blood plasma to be scrapped, and the existence of photosensitizer interpolation assembly can improve the security risk of device, increase production cost, entering on fluorescence irradiation bag (illumination bag), fluid infusion tube is all positioned at bag top, be unfavorable for operation, and photosensitizer adds assembly and is combined by 2 mouldings, the course of processing is more complicated, cause the cost of inactivating device higher.
Summary of the invention
technical problem to be solved by this invention be to provide a kind of not only can deactivation fresh plasma in virus but also blood plasma and the blood plasma product virus inactivating device that can deactivation contain virus in condensation product blood plasma.
for solving above technical problem, the present invention adopts following technical scheme:
the inactivating device of a kind of blood plasma and blood plasma product virus, comprise bottle plug puncture unit, there are illumination bag, photosensitizer, adsorption filter, blood plasma storage bag and the many infusion tubes for described bottle plug puncture unit, illumination bag, adsorption filter and blood plasma storage bag are connected successively of input and outfan, the input of described illumination bag and outfan lay respectively at relative two sides of described illumination bag, and described photosensitizer is contained in described illumination bag.
further, described inactivating device also includes the blood filtration net being connected between described bottle plug puncture unit and illumination bag, and this blood filtration net at least can be removed the condensation product in blood plasma and blood plasma product.
further, on described infusion tube, be provided with flow-stopping clip.
preferably, described photosensitizer is methylene blue.
beneficial effect of the present invention is:
the present invention, by adding blood filtration net, can remove the condensation product in blood plasma, prevents that it from stopping up adsorption filter, thereby makes its inactivation of virus that not only can be used for fresh plasma, is also applicable to the inactivation of virus of stock's blood plasma; By photosensitizer is directly added in illumination bag, omit photosensitizer and added assembly, make the simple in structure of inactivating device, operation is convenient, cost.
Brief description of the drawings
accompanying drawing 1 is the structural representation of blood plasma and blood plasma product virus inactivating device.
wherein: 1, bottle plug puncture unit; 3, illumination bag; 4, adsorption filter; 5, blood plasma reservoir bag; 6, blood filtration net; 11, flow-stopping clip; 12, input; 13, outfan.
Detailed description of the invention
below in conjunction with accompanying drawing, the present invention is further elaborated.
as shown in Figure 1, the inactivating device of a kind of blood plasma and blood plasma product virus, comprise bottle plug puncture unit 1, there are illumination bag 3, photosensitizer, adsorption filter 4, blood plasma storage bag 5 and the many infusion tubes for bottle plug puncture unit 1, illumination bag 3, adsorption filter 4 and blood plasma storage bag 5 are connected successively of input 12 and outfan 13, on infusion tube, be provided with flow-stopping clip 11, the input 12 of illumination bag 3 and outfan 13 lay respectively at relative two sides of illumination bag 3, photosensitizer is contained in illumination bag 3, and photosensitizer is methylene blue.
bottle plug puncture unit 1 comprises syringe needle and protective sleeve of syringe needle.
inactivating device also includes the blood filtration net 6 being connected between bottle plug puncture unit 1 and illumination bag 3, and this blood filtration net 6 at least can be removed the condensation product in blood plasma and blood plasma product.
adsorption filter should meet YY 0329 standard regulation.
close all flow-stopping clips, bottle plug puncture unit 1 is inserted in plasma bags, open the flow-stopping clip between blood filtration net 6 and illumination bag 3, blood plasma is by the infusion tube blood filtration net 6 of flowing through, filter screen in blood filtration net 6 is held back the large particulate matters such as the condensation product in blood plasma, the blood plasma filtering flows in illumination bag 3 through infusion tube, close the flow-stopping clip between blood filtration net 6 and illumination bag 3, tube for transfusion between heat seal blood filtration net 6 and illumination bag 3, and cut off from heat seal place, after blood plasma in illumination bag and photosensitizer (methylene blue) are mixed, put illumination bag and irradiate inactivation of viruses by regulation light source in blood constant temperature irradiates case, open the flow-stopping clip between flow-stopping clip and adsorption filter 4 and the blood plasma reservoir bag 5 between illumination bag 3 and adsorption filter 4, make blood plasma after deactivation through the infusion tube adsorption filter 4 of flowing through, to remove leukocyte residual in blood plasma and photosensitizer (methylene blue), blood plasma after filtration flows in blood plasma storage bag 5 through infusion tube, close the flow-stopping clip between adsorption filter 4 and blood plasma reservoir bag 5, tube for transfusion on heat seal blood plasma reservoir bag 5, and cut off from heat seal place, separate containing the blood plasma reservoir bag that filters blood plasma.
above-described embodiment is only explanation technical conceive of the present invention and feature, and its object is to allow person skilled in the art can understand content of the present invention and implement according to this, can not limit the scope of the invention with this.All equivalences that spirit is done according to the present invention change or modify, within all should being encompassed in protection scope of the present invention.
Claims (4)
1. the inactivating device of a blood plasma and blood plasma product virus, comprise bottle plug puncture unit (1), there is the illumination bag (3) of input (12) and outfan (13), photosensitizer, adsorption filter (4), blood plasma storage bag (5) and for by described bottle plug puncture unit (1), illumination bag (3), the many infusion tubes that adsorption filter (4) and blood plasma storage bag (5) connect successively, it is characterized in that: the input (12) of described illumination bag (3) and outfan (13) lay respectively at relative two sides of described illumination bag (3), described photosensitizer is contained in described illumination bag (3).
2. the inactivating device of blood plasma according to claim 1 and blood plasma product virus, it is characterized in that: described inactivating device also includes the blood filtration net (6) being connected between described bottle plug puncture unit (1) and illumination bag (3), this blood filtration net (6) at least can be removed the condensation product in blood plasma and blood plasma product.
3. the inactivating device of blood plasma according to claim 1 and blood plasma product virus, is characterized in that: on described infusion tube, be provided with flow-stopping clip (11).
4. the inactivating device of blood plasma according to claim 1 and blood plasma product virus, is characterized in that: described photosensitizer is methylene blue.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210549988.8A CN103861132A (en) | 2012-12-18 | 2012-12-18 | Plasma and plasma product virus inactivation device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210549988.8A CN103861132A (en) | 2012-12-18 | 2012-12-18 | Plasma and plasma product virus inactivation device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103861132A true CN103861132A (en) | 2014-06-18 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| CN201210549988.8A Pending CN103861132A (en) | 2012-12-18 | 2012-12-18 | Plasma and plasma product virus inactivation device |
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| CN (1) | CN103861132A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108939115A (en) * | 2018-05-07 | 2018-12-07 | 深圳市普特生物医学工程有限公司 | The method and system of digitization management blood-plasma virus killing |
| CN109966574A (en) * | 2016-02-02 | 2019-07-05 | 汪相伯 | A kind for the treatment of of blood products system based on riboflavin photochemical method |
Citations (8)
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|---|---|---|---|---|
| CN1249952A (en) * | 1998-10-07 | 2000-04-12 | 上海市血液中心 | Blood plasma virus deactivating method and apparatus |
| US20080050275A1 (en) * | 2001-12-05 | 2008-02-28 | Bischof Daniel F | Manual processing systems and methods for providing blood components conditioned for pathogen inactivation |
| CN201123902Y (en) * | 2007-12-26 | 2008-10-01 | 上海康德莱企业发展集团有限公司 | Blood plasma bag |
| CN201171832Y (en) * | 2008-04-03 | 2008-12-31 | 赵蔚菁 | Disposable blood virus inactivation filter |
| US20100189597A1 (en) * | 2007-03-20 | 2010-07-29 | Caridianbct Biotechnologies, Llc | Methods and Systems for Preparing Blood Products |
| CN101868255A (en) * | 2007-08-01 | 2010-10-20 | 科安比司特生物技术有限责任公司 | Whole blood pathogen inactivated |
| CN202490227U (en) * | 2012-03-22 | 2012-10-17 | 山东威高集团医用高分子制品股份有限公司 | Novel viral inactivation leukocyte-reduction blood bag |
| CN203107800U (en) * | 2012-12-18 | 2013-08-07 | 苏州排头兵药业科技有限公司 | Serums and serums product virus inactivation device |
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2012
- 2012-12-18 CN CN201210549988.8A patent/CN103861132A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1249952A (en) * | 1998-10-07 | 2000-04-12 | 上海市血液中心 | Blood plasma virus deactivating method and apparatus |
| US20080050275A1 (en) * | 2001-12-05 | 2008-02-28 | Bischof Daniel F | Manual processing systems and methods for providing blood components conditioned for pathogen inactivation |
| US20100189597A1 (en) * | 2007-03-20 | 2010-07-29 | Caridianbct Biotechnologies, Llc | Methods and Systems for Preparing Blood Products |
| CN101868255A (en) * | 2007-08-01 | 2010-10-20 | 科安比司特生物技术有限责任公司 | Whole blood pathogen inactivated |
| CN201123902Y (en) * | 2007-12-26 | 2008-10-01 | 上海康德莱企业发展集团有限公司 | Blood plasma bag |
| CN201171832Y (en) * | 2008-04-03 | 2008-12-31 | 赵蔚菁 | Disposable blood virus inactivation filter |
| CN202490227U (en) * | 2012-03-22 | 2012-10-17 | 山东威高集团医用高分子制品股份有限公司 | Novel viral inactivation leukocyte-reduction blood bag |
| CN203107800U (en) * | 2012-12-18 | 2013-08-07 | 苏州排头兵药业科技有限公司 | Serums and serums product virus inactivation device |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109966574A (en) * | 2016-02-02 | 2019-07-05 | 汪相伯 | A kind for the treatment of of blood products system based on riboflavin photochemical method |
| CN108939115A (en) * | 2018-05-07 | 2018-12-07 | 深圳市普特生物医学工程有限公司 | The method and system of digitization management blood-plasma virus killing |
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Application publication date: 20140618 |