CN103751624B - A kind of medicine and preparation method for the treatment of numb limbs and tense tendons after apoplexy - Google Patents
A kind of medicine and preparation method for the treatment of numb limbs and tense tendons after apoplexy Download PDFInfo
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Abstract
The invention discloses a kind of medicine and preparation method for the treatment of numb limbs and tense tendons after apoplexy, belong to the field of Chinese medicines; The raw material of effective ingredient of the present invention consists of: Radix seu Caulis Parthenocissi tricuspidatae, Herba Epimedii, Herba leerisae hexandrae, Radix Angelicae Pubescentis, Herba Lycopodii Obscuri, Flos Matricariae chamomillae, Caulis et Folium (Gouaniae Leptostachyae), Herba Pachysandrae Stylosae, Herba Sarcandrae, the Cortex Eucommiae, Lindera megaphylla, poinsettia, Fructus Seu Folium Kopsiae Officinalis, Semen Sinapis, black newborn mushroom and Ptyas Korros; Chinese medicine preparation of the present invention selects high-quality Chinese crude drug scientific compatibility, there is effect of expelling pathogenic wind and restoring the functions of orifices in face, blood circulation promoting and blood stasis dispelling, channels sootheing and network vessel quickening, tranquillizing and allaying excitement, to the symptom such as numb limbs and tense tendons, pain, hemiplegia, facial hemiparalysis caused after treatment apoplexy, there is significant curative effect, security performance is high, without any side effects, with low cost, can reach the object for the treatment of both the principal and secondary aspects of a disease, should be widely promoted application.
Description
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of medicine and preparation method for the treatment of numb limbs and tense tendons after apoplexy.
Background technology
Numbness of hands and feet, feels dizzy, and sees thing slur, slurred speech, and the side of face or health is dumb, and this is typical apoplexy sign, and the tremulous pulse of main brain delivering oxygen is blocked, and makes Brain organize loss of function to cause.After cerebrovas-cularaccident, brain tissue ischemia or by hematoma compression, passing, cerebral edema etc. and make cerebral tissue function impaired, After acute stage, hemiplegia becomes spastic gradually, upper limb flexing, adduction, and lower limb are in directly stretching, and tendon hyperreflexia, motor capacity can have recovery.
The sick clinical topmost performance of apoplexy is mind obstacle and motion, sensation and aphasis.Through treatment after a while, except conscious, all the other symptoms still can exist to some extent, and these symptoms are called sequela.The weight of sequela, different from the body constitution of patient and complication.
Common apoplexy sequela is as follows:
The end of 1, numb limbs and tense tendons: affected limb, especially limbs, the Face and cheek skin as finger or toe or hemiplegia side have ant to climb sensation, or have prickling sensation, or it is blunt to show as irritant reaction.Numb normal relevant with Changes in weather, weather drastic shift, humid, or before and after raining, in the situations such as cold weather, numbness feels especially obvious.
2, facial hemiparalysis: the facial muscle paralysis below the eye pouch of side.Show as nasolabial fold to shoal, ptosis of labial angle, grinningly.Drum cheek is with when blowing a whistle, and bicker is askew to strong side, sialorrhea, more obvious when speaking.
At present by wind-induced numb limbs and tense tendons, pain, hemiplegia, facial hemiparalysis etc., have a strong impact on the physical and mental health of patient, active drug is lacked to numb limbs and tense tendons after treatment apoplexy, the shortcoming of Western medicine is that action target spot is single, therefore clinical effectiveness can not be fully up to expectations, therefore, treat by wind-induced numb limbs and tense tendons, pain, hemiplegia, facial hemiparalysis the improvement of medicine be current problem demanding prompt solution.
Summary of the invention
The invention provides a kind of medicine and preparation method for the treatment of numb limbs and tense tendons after apoplexy; Chinese medicine preparation of the present invention selects high-quality Chinese crude drug scientific compatibility, there is effect of expelling pathogenic wind and restoring the functions of orifices in face, blood circulation promoting and blood stasis dispelling, channels sootheing and network vessel quickening, tranquillizing and allaying excitement, to the symptom such as numb limbs and tense tendons, pain, hemiplegia, facial hemiparalysis caused after treatment apoplexy, there is significant curative effect, security performance is high, without any side effects, with low cost, can reach the object for the treatment of both the principal and secondary aspects of a disease, should be widely promoted application.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a medicine for numb limbs and tense tendons after apoplexy, raw material composition and the parts by weight of making described effective ingredient are:
Radix seu Caulis Parthenocissi tricuspidatae 52 ~ 78 parts of Herba Epimedii 49 ~ 76 parts of Herba leerisae hexandrae 41 ~ 67 parts of Radix Angelicae Pubescentiss 36 ~ 63 parts
Herba Lycopodii Obscuri 36 ~ 62 parts of Flos Matricariae chamomillae 32 ~ 61 parts of Caulis et Folium (Gouaniae Leptostachyae) 32 ~ 61 parts of Herba Pachysandrae Stylosaes 28 ~ 55 parts
Herba Sarcandrae 27 ~ 54 parts of Cortexs Eucommiae 22 ~ 51 parts of Lindera megaphyllas 20 ~ 50 portions of poinsettia 16 ~ 44 parts
The black newborn mushroom of 12 ~ 38 parts, Fructus Seu Folium Kopsiae Officinalis 15 ~ 41 parts of Semen Sinapiss 9 ~ 30 parts of Ptyas Korross 7 ~ 26 parts.
Raw material composition and the parts by weight of making described effective ingredient are:
Radix seu Caulis Parthenocissi tricuspidatae 56 ~ 74 parts of Herba Epimedii 53 ~ 71 parts of Herba leerisae hexandrae 45 ~ 63 parts of Radix Angelicae Pubescentiss 41 ~ 59 parts
Herba Lycopodii Obscuri 40 ~ 58 parts of Flos Matricariae chamomillae 38 ~ 56 parts of Caulis et Folium (Gouaniae Leptostachyae) 36 ~ 56 parts of Herba Pachysandrae Stylosaes 33 ~ 50 parts
Herba Sarcandrae 31 ~ 50 parts of Cortexs Eucommiae 26 ~ 46 parts of Lindera megaphyllas 25 ~ 45 portions of poinsettia 21 ~ 39 parts
The black newborn mushroom of 16 ~ 34 parts, Fructus Seu Folium Kopsiae Officinalis 19 ~ 37 parts of Semen Sinapiss 13 ~ 26 parts of Ptyas Korross 11 ~ 23 parts.
Raw material composition and the parts by weight of making described effective ingredient are:
Radix seu Caulis Parthenocissi tricuspidatae 61 ~ 69 parts of Herba Epimedii 58 ~ 66 parts of Herba leerisae hexandrae 50 ~ 58 parts of Radix Angelicae Pubescentiss 46 ~ 54 parts
Herba Lycopodii Obscuri 45 ~ 53 parts of Flos Matricariae chamomillae 43 ~ 51 parts of Caulis et Folium (Gouaniae Leptostachyae) 41 ~ 51 parts of Herba Pachysandrae Stylosaes 37 ~ 45 parts
Herba Sarcandrae 36 ~ 44 parts of Cortexs Eucommiae 31 ~ 41 parts of Lindera megaphyllas 30 ~ 40 portions of poinsettia 26 ~ 34 parts
The black newborn mushroom of 21 ~ 29 parts, Fructus Seu Folium Kopsiae Officinalis 24 ~ 32 parts of Semen Sinapiss 17 ~ 21 parts of Ptyas Korross 15 ~ 19 parts.
Raw material composition and the parts by weight of making described effective ingredient are:
Radix seu Caulis Parthenocissi tricuspidatae 65 parts of Herba Epimedii 62 parts of Herba leerisae hexandrae 54 parts of Radix Angelicae Pubescentiss 50 parts
Herba Lycopodii Obscuri 49 parts of Flos Matricariae chamomillae 47 parts of Caulis et Folium (Gouaniae Leptostachyae) 46 parts of Herba Pachysandrae Stylosaes 41 parts
Herba Sarcandrae 40 parts of Cortexs Eucommiae 36 parts of Lindera megaphyllas 35 portions of poinsettia 30 parts
The black newborn mushroom of 25 parts, Fructus Seu Folium Kopsiae Officinalis 28 parts of Semen Sinapiss 19 parts of Ptyas Korross 17 parts.
Treat a preparation method for the medicine of numb limbs and tense tendons after apoplexy, comprise following processing step:
(1) Radix seu Caulis Parthenocissi tricuspidatae is put into container, carry out pulverization process, grind into powder, cross 200 order fine powders, for subsequent use;
(2) Herba Epimedii, Herba leerisae hexandrae, Flos Matricariae chamomillae, Caulis et Folium (Gouaniae Leptostachyae), the Cortex Eucommiae, Lindera megaphylla, Semen Sinapis and black newborn mushroom are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the thick paste of 1.10 ~ 1.16, for subsequent use;
(3) Radix Angelicae Pubescentis, Herba Lycopodii Obscuri, Herba Pachysandrae Stylosae, Herba Sarcandrae, Fructus Seu Folium Kopsiae Officinalis and Ptyas Korros are cleaned, immerse the alcohol solution dipping 3 ~ 4 hours of 70% of 8 times amount, heating and refluxing extraction 2 ~ 3 hours, reclaim ethanol, filter, by the thick paste of relative density 1.15 ~ 1.18 under filtrate simmer down to 60 DEG C of environment, for subsequent use;
(4) cleaned by poinsettia, dry, put into pot, slow fire parch 15 ~ 20 minutes, taking-up is dried in the air cool, grinds into powder, crosses 180 order fine powders, for subsequent use;
(5) by the fine powder obtained by above-mentioned steps (1) ~ (4) and thick paste mixing, make capsule, obtain the medicine of numb limbs and tense tendons after treatment apoplexy of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Radix seu Caulis Parthenocissi tricuspidatae: acrid in the mouth, micro-puckery, warm in nature; Return Liver Channel.Wind-expelling pain-stopping, promoting blood circulation to remove obstruction in the collateral.Cure mainly rheumatic arthralgia, apoplexy and hemiplegia, migraine and general headache, puerperal blood stasis, the raw caking of abdomen, traumatic injury, carbuncle sore tumefacting virus, ulcer being unable to heal.Supplement to the Herbal carries: " main broken old blood, puerperal blood agglomeration, the thin damage of married woman, can not diet, has block in abdomen; Difficulty in micturition, also under leucorrhea, the capable heart in sky is vexed, and decoction it, also infusing drugs in wine." multiple extracorporeal bacteria inhibitor test method proves that the fresh juice of this product, water decoction, decocting ethanol extract etc. all have obvious bacteriostasis to staphylococcus aureus, Staphylococcus albus, Hemolytic streptococcus, micrococcus catarrhalis, diphtheria corynebacterium, escherichia coli, Bacillus typhi, Salmonella paratyphi, Amur dysentery bacterium, shigella flexneri, sonne bacillus, bacillus pyocyaneus, bacillus enteritidis, hog cholera Salmonella etc.
Herba Epimedii: acrid in the mouth, sweet, warm in nature; Enter liver, kidney two warp.Kidney invigorating and YANG supporting, expelling wind and removing dampness, strengthening the tendons and bones.Cure mainly soreness of the waist and knees, rheumatic arthralgia, hemiplegia, extremity are meciless.Modern medicine study confirms, Herba Epimedii has more significant inhibitory action to Staphylococcus albus, staphylococcus aureus, has slight inhibitory action to Nai Shi micrococcus catarrhalis, Diplococcus pneumoniae, hemophilus influenza.
Herba leerisae hexandrae: taste is put down, and property is pungent.Dispelling wind to relieve the exterior syndrome, dampness removing, removing obstruction in the collateral to relieve pain.Cure mainly flu, headache body pain, malaria, leucorrhea, lower limbs edema, dysuria, arthralgia pain is numb." Traditional Chinese Medicine in Sichuan will " carries: " energy expelling cold and relieving exterior syndrome, the meridian dredging.Treating malaria disease, flu head-body-pain.”
Radix Angelicae Pubescentis: acrid in the mouth, hardship, tepor; Return liver, kidney, urinary bladder channel.Expelling wind and dampness, dispersing cold for relieving pain.For anemofrigid-damp arthralgia, lumbocrural pain, few cloudy volt wind headache, headache analgesic.Carry according to " Bencao Tujing ": " the auxiliary Radix Angelicae Pubescentis of Ramulus Mori, Radix Angelicae Pubescentis searches wind, dissipating cold pain relieving and blood stasis dispelling; Ramulus Mori wind-damp dispelling and the meridian dredging walks crosswise extremity.Papillary, treatment anemofrigid-damp arthralgia function strengthens, especially upper extremity pain, scapulohumeral periarthritis." modern medicine study confirmation; the platelet aggregation that angelol extract can suppress ADP external evoked; dichloromethane extract has the activity of antagonize calcium channel blocker receptor; the bergapten included, xanthotoxin, isoimperatorin have obvious spasmolysis, has antalgic and sedative, anti-inflammatory, antibacterial effect in addition.
Herba Lycopodii Obscuri: sour in the mouth, warm in nature, nontoxic; Return lung, kidney channel.Expelling wind and removing dampness, channels sootheing and network vessel quickening, blood circulation promoting and blood stasis dispelling.Cure mainly rheumatic arthralgia, lumbago and skelalgia, numb limbs and tense tendons, osteopatia sprain, poliomyelitis sequela.Supplement to the Herbal carries: " get rhizome infusing drugs in wine, remove wind blood, except wind scabies, should be old.”
Flos Matricariae chamomillae: mildly bitter flavor, Gan Xiang.Improving eyesight, moves back liver-fire.Cure for insomnia, high blood, scalds, the wound of vesicle, inflammation, ulcer etc.Side modern medicine study confirms, effect of the helpful sleep of Flos Matricariae chamomillae, alleviates inflammation and the pain symptom of patient, alleviates the insomnia caused by neurotic skin pruritus.
Caulis et Folium (Gouaniae Leptostachyae): puckery, hardship, cool in nature; Return spleen channel.Heat-clearing and toxic substances removing, analgesic hemostatic.Cure mainly heating, burn and scald, skin infection, stomachache, rheumatalgia, traumatic hemorrhage.
Herba Pachysandrae Stylosae: bitter in the mouth, pungent, warm in nature; Enter spleen, kidney two warp.Expelling wind and removing dampness, promoting blood circulation and stopping pain.Cure mainly rheumatic arthralgia, numb limbs and tense tendons, impairment caused by overstrain lumbago, traumatic injury, headache." Guizhou medical herbs " carries: " invigorate blood circulation, blood stasis dispelling, pain relieving.”
Herba Sarcandrae: bitter in the mouth, pungent, property is put down; GUIXIN, Liver Channel.Expelling wind and removing dampness, promoting blood circulation to remove blood stasis, heat-clearing and toxic substances removing.Cure mainly numb limbs and tense tendons, traumatic injury, fracture, dysmenorrhes, the stagnant stomachache of the stasis of blood in puerperal, pneumonia, striving property appendicitis, acute gastroenteritis, bacillary dysentery, cholecystitis, abscess, stomatitis, rheumatic arthralgia.
The Cortex Eucommiae: sweet in the mouth, micro-pungent, warm in nature; Enter liver, kidney channel.Invigorating the liver and kidney, bone and muscle strengthening.Cure mainly spinal column ache, rheumatic arthralgia.Carry according to Prescriptions Worth Thousand Gold for Emergencies: " liver and kidney tonifying, fills blood for function wind-damp dispelling, stopping numbness pain ... be affected by the cold damp, chills and pain of the waist and kness, podomere joint stuffiness, or benumbs meciless, fear of cold happiness temperature." modern medicine study confirms, the Cortex Eucommiae has sedation to nerve centre, can strengthen the immunologic function of cell, promotes cortisol secretion and cAMP in plasma and cGMP metabolism.
Lindera megaphylla: acrid in the mouth, micro-hardship, warm in nature; Return liver, stomach warp.Expelling wind and removing dampness, warming middle-JIAO to promote flow of QI, reducing swelling and alleviating pain.Cure mainly rheumatic arthralgia, numb limbs and tense tendons pain, coldness and pain in the epigastrium, hernia pain, laryngopharynx swelling and pain, tinea skin ulcer pruritus.
Poinsettia: bitter in the mouth, cool in nature.Heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling.Cure mainly upper respiratory tract infection, oral ulcer, pneumonia, mastitis, enteritis, bacillary dysentery, urinary tract infection, furuncle carbuncle, eczema, traumatic injury, heat clearing away." the practical Chinese herbal medicine in Guangxi newly selects " carries: " anti-inflammation.Control acute upper respiratory tract inflammation, pneumonia, tonsillitis, oral ulcer, mastitis, chronic pelvic inflammatory disease, dysentery, diarrhoea, venom.”
Fructus Seu Folium Kopsiae Officinalis: bitter in the mouth, pungent, warm in nature, poisonous.Anti-inflammatory analgetic, relaxing muscles and tendons and activating QI and blood in the collateral.Cure mainly pharyngolaryngitis, tonsillitis, rheumatic ostalgia, numb limbs and tense tendons.
Semen Sinapis: acrid in the mouth, warm in nature; Return lung meridian.Warming spleen and stomach for dispelling cold, promoting the circulation of QI eliminating phlegm, the meridian dredging, detumescence poison.Cure mainly cold syndrome of the stomach and tell food, trusted subordinate's pain, lung cold cough, arthralgia aggravated by cold, sore throat, carbuncle of yin nature, the tuberculosis of bone and joint, traumatic injury." detailed outline " carries: " warming spleen and stomach for dispelling cold, eliminating phlegm profit key.Control cold syndrome of the stomach and tell food, lung cold cough, air-cooled pain due to disorder of QI, locked mouth lockjaw.Dissipation carbuncle, blood stasis.”
Black newborn mushroom: acrid in the mouth, sweet, warm in nature.Expelling wind and cold, relaxing muscles and tendons and activating QI and blood in the collateral.Cure mainly rheumatic arthralgia, numb limbs and tense tendons, tetany.
Ptyas Korros: sweet in the mouth, salty, property is put down; Return liver, kidney channel.Wind-expelling pain-stopping, relaxing muscles and tendons and activating QI and blood in the collateral.Cure mainly rheumatic Bi syndrome, waist and leg ache, numb limbs and tense tendons, half body is fried then, poliomyelitis.
The present invention compared with prior art, has following beneficial effect:
Chinese medicine preparation of the present invention selects high-quality Chinese crude drug scientific compatibility, there is effect of expelling pathogenic wind and restoring the functions of orifices in face, blood circulation promoting and blood stasis dispelling, channels sootheing and network vessel quickening, tranquillizing and allaying excitement, to the symptom such as numb limbs and tense tendons, pain, hemiplegia, facial hemiparalysis caused after treatment apoplexy, there is significant curative effect, security performance is high, without any side effects, with low cost, can reach the object for the treatment of both the principal and secondary aspects of a disease, should be widely promoted application.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of effective ingredient of the present invention and weight are:
Radix seu Caulis Parthenocissi tricuspidatae 74g Herba Epimedii 71g Herba leerisae hexandrae 63g Radix Angelicae Pubescentis 59g
Herba Lycopodii Obscuri 58g Flos Matricariae chamomillae 56g Caulis et Folium (Gouaniae Leptostachyae) 56g Herba Pachysandrae Stylosae 50g
Herba Sarcandrae 50g Cortex Eucommiae 46g Lindera megaphylla 45g poinsettia 39g
The black newborn mushroom 26g Ptyas Korros 23g of Fructus Seu Folium Kopsiae Officinalis 37g Semen Sinapis 34g.
Treat a preparation method for the medicine of numb limbs and tense tendons after apoplexy, comprise following processing step:
(1) Radix seu Caulis Parthenocissi tricuspidatae is put into container, carry out pulverization process, grind into powder, cross 200 order fine powders, for subsequent use;
(2) Herba Epimedii, Herba leerisae hexandrae, Flos Matricariae chamomillae, Caulis et Folium (Gouaniae Leptostachyae), the Cortex Eucommiae, Lindera megaphylla, Semen Sinapis and black newborn mushroom are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the thick paste of 1.10 ~ 1.16, for subsequent use;
(3) Radix Angelicae Pubescentis, Herba Lycopodii Obscuri, Herba Pachysandrae Stylosae, Herba Sarcandrae, Fructus Seu Folium Kopsiae Officinalis and Ptyas Korros are cleaned, immerse the alcohol solution dipping 3 ~ 4 hours of 70% of 8 times amount, heating and refluxing extraction 2 ~ 3 hours, reclaim ethanol, filter, by the thick paste of relative density 1.15 ~ 1.18 under filtrate simmer down to 60 DEG C of environment, for subsequent use;
(4) cleaned by poinsettia, dry, put into pot, slow fire parch 15 ~ 20 minutes, taking-up is dried in the air cool, grinds into powder, crosses 180 order fine powders, for subsequent use;
(5) by the fine powder obtained by above-mentioned steps (1) ~ (4) and thick paste mixing, make capsule, obtain the medicine of numb limbs and tense tendons after treatment apoplexy of the present invention.
Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 2 (every 0.5g), warm water delivery service after meal; Within 5 days, be 1 course for the treatment of, 2 ~ 3 courses for the treatment of can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material composition of effective ingredient of the present invention and weight are:
Radix seu Caulis Parthenocissi tricuspidatae 69g Herba Epimedii 66g Herba leerisae hexandrae 58g Radix Angelicae Pubescentis 54g
Herba Lycopodii Obscuri 53g Flos Matricariae chamomillae 51g Caulis et Folium (Gouaniae Leptostachyae) 51g Herba Pachysandrae Stylosae 45g
Herba Sarcandrae 44g Cortex Eucommiae 41g Lindera megaphylla 40g poinsettia 34g
The black newborn mushroom 21g Ptyas Korros 19g of Fructus Seu Folium Kopsiae Officinalis 32g Semen Sinapis 29g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.Embodiment 3
The raw material composition of effective ingredient of the present invention and weight are:
Radix seu Caulis Parthenocissi tricuspidatae 65g Herba Epimedii 62g Herba leerisae hexandrae 54g Radix Angelicae Pubescentis 50g
Herba Lycopodii Obscuri 49g Flos Matricariae chamomillae 47g Caulis et Folium (Gouaniae Leptostachyae) 46g Herba Pachysandrae Stylosae 41g
Herba Sarcandrae 40g Cortex Eucommiae 36g Lindera megaphylla 35g poinsettia 30g
The black newborn mushroom 19g Ptyas Korros 17g of Fructus Seu Folium Kopsiae Officinalis 28g Semen Sinapis 25g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.Embodiment 4
The raw material composition of effective ingredient of the present invention and weight are:
Radix seu Caulis Parthenocissi tricuspidatae 61g Herba Epimedii 58g Herba leerisae hexandrae 50g Radix Angelicae Pubescentis 46g
Herba Lycopodii Obscuri 45g Flos Matricariae chamomillae 43g Caulis et Folium (Gouaniae Leptostachyae) 41g Herba Pachysandrae Stylosae 37g
Herba Sarcandrae 36g Cortex Eucommiae 31g Lindera megaphylla 30g poinsettia 26g
The black newborn mushroom 17g Ptyas Korros 15g of Fructus Seu Folium Kopsiae Officinalis 24g Semen Sinapis 21g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.Embodiment 5
The raw material composition of effective ingredient of the present invention and weight are:
Radix seu Caulis Parthenocissi tricuspidatae 56g Herba Epimedii 53g Herba leerisae hexandrae 45g Radix Angelicae Pubescentis 41g
Herba Lycopodii Obscuri 40g Flos Matricariae chamomillae 38g Caulis et Folium (Gouaniae Leptostachyae) 36g Herba Pachysandrae Stylosae 33g
Herba Sarcandrae 31g Cortex Eucommiae 26g Lindera megaphylla 25g poinsettia 21g
The black newborn mushroom 13g Ptyas Korros 11g of Fructus Seu Folium Kopsiae Officinalis 19g Semen Sinapis 16g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the medicine of numb limbs and tense tendons after treatment apoplexy, the routine clinical observation of numb limbs and tense tendons patient 110 after the apoplexy that selection is made a definite diagnosis, patient is divided into treatment group and matched group two groups at random, treatment group 55 example, wherein male 26 example, women 29 example, 19 ~ 49 years old age, 34 years old mean age, the course of disease 1 ~ 3 year; Matched group 55 example, wherein male 27 example, women 28 example, 20 ~ 48 years old age, 34 years old mean age, the course of disease 1 ~ 2 year; The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes medicine of the present invention, oral, every day 2 times, each 1 time sooner or later, each 2 (every 0.5g), warm water delivery service after meal; Within 5 days, be 1 course for the treatment of, take 2 ~ 3 courses for the treatment of continuously, the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Matched group is taken and is pricked punching ten triplex pill, and night is warm boiled water just before going to bed.Every 5 heavy 1g, 1 ~ 1.8g/ time, 1 times/day, children's is by subtracting or following the doctor's advice.
3, efficacy determination:
(1) cure: numb and adjoint all paraesthesia symptoms disappear completely, and physical recovery is normal.
(2) effective: pain and numbness obviously alleviates, simultaneous phenomenon improves, and health recovers normal substantially.
(3) effective: pain and numbness alleviates to some extent, simultaneous phenomenon is alleviated, and primary symptom still brings out impact life.
(4) invalid: pain and numbness is unchanged, simultaneous phenomenon improve or without improvement.
4, result:
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, Zeng, female, 23 years old, people from Yingkou, Liaoning.Patient falls down downstairs time, and head lands, obnubilation about 10 minutes, symptoms such as occurring that mental derangement, pale complexion, cold sweat go out after waking up, have a headache, be dizzy, nauseating.Examine my institute, examine as numb limbs and tense tendons after apoplexy, give medicine of the present invention, after taking 1 course for the treatment of, above-mentioned symptom is clearly better, and after continuing to take 1 course for the treatment of, recovery from illness, follows up a case by regular visits to after 1 year without recurrence.
2, certain is relied, man, 38 years old, Zhejiang Jiaxing people.Patient falls in a swoon at work, is sent to hospital, and doctor makes a definite diagnosis suffers from apoplexy, through hospitalize, the state of an illness takes a turn for the better to some extent, but numb limbs and tense tendons does not disappear, and introduces to our hospital by friend, after taking 1 course for the treatment of of Chinese medicine preparation of the present invention, numb limbs and tense tendons symptom is clearly better, after continuing to take 2 courses for the treatment of of Chinese medicine preparation of the present invention, and numb limbs and tense tendons transference cure, physical recovery is normal, follows up a case by regular visits to without recurrence after 1 year.
3, Gong, man, 42 years old, Chao County of Anhui Province Lakers.Numb limbs and tense tendons after patient's apoplexy, through treatment, after leaving hospital, brains is not still regained consciousness, and with constipation, the diseases such as ambiguous, slight Hypertension, numb limbs and tense tendons of speaking.Take medicine of the present invention, after taking 1 course for the treatment of, patient can initiatively take in guests, and numb limbs and tense tendons symptom is alleviated to some extent, and after taking 2 courses for the treatment of, clear utterance of speaking, blood pressure is normal, numb limbs and tense tendons transference cure, and physical recovery is healthy.
4, soup, female, 48 years old, Quanzhou, Fujian people.Numb limbs and tense tendons after the apoplexy that patient causes due to long-term microcirculation disturbance, go hospitalize, through diagnosis simultaneously also with symptoms such as cerebral thrombosis, hypertension, nerve compression, have no any improvement through treatment, send my place of institute here, so take medicine of the present invention through friend recommendation, after taking the present invention's 1 curative effect, above-mentioned symptom obviously alleviates, and fully recovers, follow up a case by regular visits to and do not recur after half a year after taking the present invention's 3 curative effects.
5, Liu, female, 38 years old, people from Handan, Hebei.After patient's cerebral infarction is hospitalized for treatment, the state of an illness is controlled substantially, but occasionally has the symptoms such as numb limbs and tense tendons to occur, multi-treatment is without positive effect.Recommend to take medicine of the present invention by doctor, after taking the present invention's 1 curative effect, above-mentioned symptom obviously alleviates, and fully recovers, follow up a case by regular visits to and do not recur after half a year after taking the present invention's 2 curative effects.
6, side certain, female, 43 years old, people from Jiujiang.Patient suffered from apoplexy before 2 years, turn for the better by and large after treatment, between or have numb limbs and tense tendons, going hospitalize, is apoplexy sequela through diagnosis, starts to take medicine of the present invention through friend recommendation, after taking the present invention's 1 curative effect, above-mentioned symptom obviously alleviates, and fully recovers, follow up a case by regular visits to and do not recur after half a year after taking the present invention's 2 curative effects.
Claims (5)
1. treat a medicine for numb limbs and tense tendons after apoplexy, it is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Radix seu Caulis Parthenocissi tricuspidatae 52 ~ 78 parts of Herba Epimedii 49 ~ 76 parts of Herba leerisae hexandrae 41 ~ 67 parts of Radix Angelicae Pubescentiss 36 ~ 63 parts
Herba Lycopodii Obscuri 36 ~ 62 parts of Flos Matricariae chamomillae 32 ~ 61 parts of Caulis et Folium (Gouaniae Leptostachyae) 32 ~ 61 parts of Herba Pachysandrae Stylosaes 28 ~ 55 parts
Herba Sarcandrae 27 ~ 54 parts of Cortexs Eucommiae 22 ~ 51 parts of Lindera megaphyllas 20 ~ 50 portions of poinsettia 16 ~ 44 parts
The black newborn mushroom of 12 ~ 38 parts, Fructus Seu Folium Kopsiae Officinalis 15 ~ 41 parts of Semen Sinapiss 9 ~ 30 parts of Ptyas Korross 7 ~ 26 parts.
2. a kind of medicine for the treatment of numb limbs and tense tendons after apoplexy according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Radix seu Caulis Parthenocissi tricuspidatae 56 ~ 74 parts of Herba Epimedii 53 ~ 71 parts of Herba leerisae hexandrae 45 ~ 63 parts of Radix Angelicae Pubescentiss 41 ~ 59 parts
Herba Lycopodii Obscuri 40 ~ 58 parts of Flos Matricariae chamomillae 38 ~ 56 parts of Caulis et Folium (Gouaniae Leptostachyae) 36 ~ 56 parts of Herba Pachysandrae Stylosaes 33 ~ 50 parts
Herba Sarcandrae 31 ~ 50 parts of Cortexs Eucommiae 26 ~ 46 parts of Lindera megaphyllas 25 ~ 45 portions of poinsettia 21 ~ 39 parts
The black newborn mushroom of 16 ~ 34 parts, Fructus Seu Folium Kopsiae Officinalis 19 ~ 37 parts of Semen Sinapiss 13 ~ 26 parts of Ptyas Korross 11 ~ 23 parts.
3. a kind of medicine for the treatment of numb limbs and tense tendons after apoplexy according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Radix seu Caulis Parthenocissi tricuspidatae 61 ~ 69 parts of Herba Epimedii 58 ~ 66 parts of Herba leerisae hexandrae 50 ~ 58 parts of Radix Angelicae Pubescentiss 46 ~ 54 parts
Herba Lycopodii Obscuri 45 ~ 53 parts of Flos Matricariae chamomillae 43 ~ 51 parts of Caulis et Folium (Gouaniae Leptostachyae) 41 ~ 51 parts of Herba Pachysandrae Stylosaes 37 ~ 45 parts
Herba Sarcandrae 36 ~ 44 parts of Cortexs Eucommiae 31 ~ 41 parts of Lindera megaphyllas 30 ~ 40 portions of poinsettia 26 ~ 34 parts
The black newborn mushroom of 21 ~ 29 parts, Fructus Seu Folium Kopsiae Officinalis 24 ~ 32 parts of Semen Sinapiss 17 ~ 21 parts of Ptyas Korross 15 ~ 19 parts.
4. a kind of medicine for the treatment of numb limbs and tense tendons after apoplexy according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Radix seu Caulis Parthenocissi tricuspidatae 65 parts of Herba Epimedii 62 parts of Herba leerisae hexandrae 54 parts of Radix Angelicae Pubescentiss 50 parts
Herba Lycopodii Obscuri 49 parts of Flos Matricariae chamomillae 47 parts of Caulis et Folium (Gouaniae Leptostachyae) 46 parts of Herba Pachysandrae Stylosaes 41 parts
Herba Sarcandrae 40 parts of Cortexs Eucommiae 36 parts of Lindera megaphyllas 35 portions of poinsettia 30 parts
The black newborn mushroom of 25 parts, Fructus Seu Folium Kopsiae Officinalis 28 parts of Semen Sinapiss 19 parts of Ptyas Korross 17 parts.
5. as described in any one of Claims 1 to 4, treat a preparation method for the medicine of numb limbs and tense tendons after apoplexy, it is characterized in that: comprise following processing step:
(1) Radix seu Caulis Parthenocissi tricuspidatae is put into container, carry out pulverization process, grind into powder, cross 200 orders and obtain fine powder, for subsequent use;
(2) Herba Epimedii, Herba leerisae hexandrae, Flos Matricariae chamomillae, Caulis et Folium (Gouaniae Leptostachyae), the Cortex Eucommiae, Lindera megaphylla, Semen Sinapis and black newborn mushroom are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the thick paste of 1.10 ~ 1.16, for subsequent use;
(3) Radix Angelicae Pubescentis, Herba Lycopodii Obscuri, Herba Pachysandrae Stylosae, Herba Sarcandrae, Fructus Seu Folium Kopsiae Officinalis and Ptyas Korros are cleaned, immerse the alcohol solution dipping 3 ~ 4 hours of 70% of 8 times amount, heating and refluxing extraction 2 ~ 3 hours, reclaim ethanol, filter, by the thick paste of relative density 1.15 ~ 1.18 under filtrate simmer down to 60 DEG C of environment, for subsequent use;
(4) cleaned by poinsettia, dry, put into pot, slow fire parch 15 ~ 20 minutes, taking-up is dried in the air cool, grinds into powder, crosses 180 orders and obtains fine powder, for subsequent use;
(5) by the fine powder obtained by above-mentioned steps (1) ~ (4) and thick paste mixing, make capsule, obtain the medicine of numb limbs and tense tendons after described treatment apoplexy.
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| CN101757569A (en) * | 2010-01-19 | 2010-06-30 | 泰一和浦（北京）中医药研究院有限公司 | Traditional Chinese medicine composition for treating cerebral thrombosis and cerebral infarction and preparation method thereof |
| CN102961509A (en) * | 2011-08-30 | 2013-03-13 | 苑发 | Traditional Chinese medicine for treating hemiplegia |
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| CN101757569A (en) * | 2010-01-19 | 2010-06-30 | 泰一和浦（北京）中医药研究院有限公司 | Traditional Chinese medicine composition for treating cerebral thrombosis and cerebral infarction and preparation method thereof |
| CN102961509A (en) * | 2011-08-30 | 2013-03-13 | 苑发 | Traditional Chinese medicine for treating hemiplegia |
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