CN103745086A - Immediate in vitro diagnosis device based on cloud computing and image identification - Google Patents
Immediate in vitro diagnosis device based on cloud computing and image identification Download PDFInfo
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- CN103745086A CN103745086A CN201310697197.4A CN201310697197A CN103745086A CN 103745086 A CN103745086 A CN 103745086A CN 201310697197 A CN201310697197 A CN 201310697197A CN 103745086 A CN103745086 A CN 103745086A
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Abstract
The invention relates to an immediate in vitro diagnosis device based on cloud computing and image identification and an electronic information processing framework. The device and the corresponding software framework separate collecting and processing of in vitro diagnosis information. Signal collecting and result displaying are performed on a human body tissue or a body fluid sample on a miniature in vitro diagnosis device user terminal; the part needing computing and analyzing is transferred to a large server based on cloud computing, and automatic signal analysis and diagnosis are finished on the server. Meanwhile, a user can scan and obtain previous diagnosis results stored on the cloud computing server on multiple platforms. With the design, the in vitro diagnosis device is greatly simplified, and the immediate in vitro diagnosis device has the advantages of being high in sensitivity, low in manufacturing cost, reliable in performance, easy and convenient to use and the like.
Description
Technical field
The present invention relates to a kind ofly based on computer technologies such as cloud computing and image recognitions, the instant in-vitro diagnosis equipment to tissue or body fluid, belongs to medical diagnosis field.
Background technology
In-vitro diagnosis equipment refers to outside human body, by tissue or humoral sample, as blood, urine, seminal fluid, skin etc., detects and obtains the equipment of clinical diagnosis information.Instant in-vitro diagnosis is to detect the basic skills of the whether ill and severity extent of patient, and its result directly has influence on doctor's diagnosis and patient's healthy, life security.And along with the progress of modern medicine science and technology and the development of related discipline, instant more and more robotization of vitro detection equipment.The large-scale diagnostic device that Hospitals at Present is used, is digit microscope, computer all-in-one machine substantially, and cost is high, needs professional to operate, the small hospital that is not therefore suitable for family and has quite modest financial resources.And existing family expenses detection kit on market only can be passed through biochemical immunity specific reaction, judge having or not of certain pathogen, numerical value that cannot quantitative.The major reason that wherein, cannot realize the robotization of family expenses is: complicated analytical calculation needs high performance computational resource.For example: in semen analysis, thereby the tracking of sperm, classification are obtained to spermatozoon activity report, relate to complicated graphical analysis and computerized algorithm.
Summary of the invention
The present invention overcomes these traditional technology barriers by helping, and invents a kind of new construction system for in-vitro diagnosis equipment, utilizes cloud computing technology and image automatic identification technology, makes the more miniaturization of in-vitro diagnosis equipment, portability and robotization.As shown in Figure 1, the present invention comprises three parts, two hardware components and a software section:
1. the equipment of user terminal (Fig. 1-105).This equipment is furnished with microscope equipment and digital image acquisition device, can pass through sample bearing device (Fig. 1-108) for tissue sample, as blood, urine, seminal fluid, skin etc., gather signal, image or related pathologies information original or that biochemical reaction generates afterwards.(this part patent of invention is independently applied for)
2. cloud computing server, i.e. long-range distributed computer or large server (Fig. 1-101).This server is comprised of one or more robot calculator, can provide processing service (Fig. 1-102), the stores service (Fig. 1-103) to electronic information according to demand, and can, according to the size of demand, flexibly change the service ability in the unit interval.Existing a lot of cloud computing service provider on market, in the present invention, cloud computing server is only as one of the carrier of software section in invention.
3. control the software architecture of electronic information.This software architecture comprises two parts: on the equipment of user terminal with cloud computing server on.
A. the software on user terminal, opertaing device hardware system is to the collection of signal, pre-service (signal compression, filtration), and then passes the signal along on the cloud computing server with this linking of devices.After signal is finished dealing with on cloud computing server, pass result back this equipment, this software is shown to user by result again.
B. the software moving on cloud computing server, is responsible for the signal that receiving terminal equipment is sent, and according to calculated amount distributes calculation resources, carries out information processing.Contents processing comprises: decompress to the received signal, the automated analysis to still image or video, and with the comparing of existing pre-deposit data, to the classification of information, quantification, regression forecasting, medical diagnosis on disease etc.After analysis completes, analysis result is sent back to subscriber terminal equipment.
In practical operation, user only need to put into sample the information collecting device of user terminal, and above-described analytic process has been controlled automatically by software, and user can see analysis result at short notice.And the result after each original electron data message using and analysis will be stored in (Fig. 1-103) on subscriber terminal equipment and cloud computing server.Therefore, user can check by internet analyzing and diagnosing result and original electronic data information (Fig. 1-109,110) on the platform of a plurality of and cloud computing server networking.
Accompanying drawing explanation
Fig. 1: invention integral frame schematic diagram.
101: cloud computing server (schematic diagram)
102: the calculation server in cloud computing server
103: the storage server in cloud computing server
104: data message sends, transmits schematic diagram
105: the information collecting device of user terminal (schematic diagram)
106: the display device on the information collecting device of user terminal
107: sample carrier insert port
108: sample carrier (schematic diagram)
109: the hand-held mobile Internet platform such as mobile phone (schematic diagram)
110: the small-size computers such as PC (schematic diagram)
Fig. 2: be applied to spermatozoon activity testing result.
201: the sperm identifying by the image recognition software on cloud computing server
202: the abnormality in outer shape sperm identifying
203: the unidentified sperm going out
Embodiment
Examples of implementation: family expenses spermatozoon activity detects
At present, the sperm quality detecting instrument that large hospital is used is generally digit microscope and computer all-in-one machine, and cost is high, is inconvenient to move, and after professional need to train, could operate, the small-middle hospital that is not suitable for family and has quite modest financial resources.And existing family expenses sperm detection kit on market only can detect sperm concentration and whether reach the minimum standard that the World Health Organization (WHO) sets, cannot provide precise figures, more cannot provide spermatozoon activity information, result does not possess physiology and diagnostic value.Therefore, personal accurately sperm quality detection is automatically analyzed, and is a huge market vacancy.The present invention will adopt state-of-the-art graphical analysis, machine learning scheduling algorithm and cloud computing technology, and sperm quality is carried out to quantitative test.Analysis content comprises: the sperm number in unit volume, and the locomotor activity of sperm (ratios of various sport ranks), and the form of sperm etc.This series products will make user in own home, just can obtain accurately effectively sperm quality analysis report, reach the effect of early diagnosis, prevention morning, early treatment, the mental handicape of simultaneously avoiding hospital to carry out reproduction inspection, and unnecessary loaded down with trivial details formality.
Detailed process is as follows: user splashes on a sample carrier by a seminal fluid and puts into the information collecting device (summary of the invention 1) of user terminal, this equipment is by inner micro image collection system, enroll 10 second video data, by the software in equipment (summary of the invention 3a), video compress is delivered on cloud computing server (summary of the invention 2).Software on Cloud Server (summary of the invention 3b) is decompressed video data first, then according to the image information in video data, identify sperm (Fig. 2), analyze as follows immediately:
A. sperm concentration: according to the sperm count in the unit area identifying in video, then be converted into the sperm count in unit volume, i.e. sperm concentration by the liquid level thickness of liquid carrier.
B. sperm motility: follow the trail of the sperm identifying in video, follow the trail of sperm position and over time the motion of sperm is carried out to hierarchical statistics, and calculate averaged curve movement rate, point-to-point speed, sperm side oscillation, sperm is whipped frequency etc.
C. sperm morphology: according to the sperm identifying in video, compare with the standard sperm profile being pre-stored on cloud computing server, judge that whether sperm profile is healthy.
After calculating on cloud computing server completes, result of calculation is transferred back to user terminal and result is shown to user.User also can be according to the username and password of having registered, on other-end equipment, as on its PC (Fig. 1-110), mobile phone (Fig. 1-109), sign in in the system being linked with cloud computing server, see repeated detection result that this user once did and original sperm video record.
Claims (6)
1. the instant in-vitro diagnosis equipment based on cloud computing and image recognition and electronic information are processed a framework, it is characterized in that (a) this diagnostic device separates the acquisition and processing of information, transfers to the part that needs computational analysis on the server based on cloud computing; (b) equipment that is positioned at user side only carries out information acquisition, pre-service, transmission, reception and display analysis result to user profile and sample; (c) software that is positioned at cloud computing server carries out graphical analysis and the data analysis of robotization; (d) analysis result is stored on cloud computing server, and can allow user get analysis result by the platform of various networkings.
2. the equipment of user terminal according to claim 1, it is characterized in that: this kind of equipment can Information Monitoring from multiple or a certain body fluid or biological tissue, collectable data type: direct digitized optical image, the form of the reaction product after biological or chemical reaction, color, the electric signal discharging.
3. the equipment of user terminal according to claim 1, is characterized in that, according to the programmable interface of cloud computing platform (API) design and running software on it, pretreated data message is sent on cloud computing server.
4. the equipment of user terminal according to claim 1, is characterized in that, according to the programmable interface of cloud computing platform, receives the information after analyzing on cloud computing server, and analysis result is showed to user with the form of icon, numeral, word.
5. cloud computing server according to claim 1, is characterized in that, the information of sending according to the equipment of user side, and Automatically invoked corresponding software program is carried out information processing; Contents processing comprises: decompress to the received signal, the automated analysis to still image or video, and with the comparing of existing pre-deposit data, to the classification of information, quantification, regression forecasting, medical diagnosis on disease etc.
6. cloud computing server according to claim 1, it is characterized in that, can hold equipment or user profile according to specific user, store for a long time this user's raw data and analysis result, so that user browses, obtains passing analysis result on multiple internet platform.
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CN104931680A (en) * | 2015-07-06 | 2015-09-23 | 北京大学口腔医学院 | Portable urine protein detection system and method based on mobile Internet |
CN106096254A (en) * | 2016-06-03 | 2016-11-09 | 宁波大红鹰学院 | A kind of medical service system and method |
CN108062748A (en) * | 2016-11-07 | 2018-05-22 | 深圳大森智能科技有限公司 | A kind of image identification system and image-recognizing method |
CN109406506A (en) * | 2018-12-06 | 2019-03-01 | 北京腾康汇医科技有限公司 | A kind of shared self-rated health terminal and test method |
CN110866937A (en) * | 2019-10-25 | 2020-03-06 | 深圳市瑞图生物技术有限公司 | Sperm movement track reconstruction and classification method |
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CN104931680A (en) * | 2015-07-06 | 2015-09-23 | 北京大学口腔医学院 | Portable urine protein detection system and method based on mobile Internet |
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CN109406506A (en) * | 2018-12-06 | 2019-03-01 | 北京腾康汇医科技有限公司 | A kind of shared self-rated health terminal and test method |
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CN110866937A (en) * | 2019-10-25 | 2020-03-06 | 深圳市瑞图生物技术有限公司 | Sperm movement track reconstruction and classification method |
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Application publication date: 20140423 |