CN103623122B - A kind of Chinese medicine for hemorrhoid and preparation method thereof - Google Patents
A kind of Chinese medicine for hemorrhoid and preparation method thereof Download PDFInfo
- Publication number
- CN103623122B CN103623122B CN201310699246.8A CN201310699246A CN103623122B CN 103623122 B CN103623122 B CN 103623122B CN 201310699246 A CN201310699246 A CN 201310699246A CN 103623122 B CN103623122 B CN 103623122B
- Authority
- CN
- China
- Prior art keywords
- parts
- chinese medicine
- hemorrhoid
- water
- rhizoma
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine for hemorrhoid and preparation method thereof.Chinese medicine for hemorrhoid of the present invention, is made up of the raw material of Chinese medicine medicine of following weight portion: leaf 15-25 part of washing the dishes, Rhizoma Angiopteridis Fokiensis 8-16 part, Herba Sedi 8-16 part, Cortex Phellodendri 8-16 part, Rhizoma Coptidis 3-9 part, Radix Angelicae Sinensis 8-16 part, Fructus Forsythiae 8-16 part, Natrii Sulfas 3-9 part, Alumen 3-9 part, Spina Gleditsiae 3-9 part, Radix Gentianae Macrophyllae 6-12 part, Catharsii molossi 3-9 part.Chinese medicine for hemorrhoid of the present invention, has heat clearing and damp drying, removing toxic substances and promoting subsidence of swelling, cooling blood for hemostasis, effect of promoting blood circulation and stopping pain, for various types of hemorrhoid.Clinical test results shows, its 1 the course for the treatment of obvious effective rate up to 48.81%, 1 the course for the treatment of total effective rate up to 95.23%.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine for hemorrhoid and preparation method thereof.
Background technology
Hemorrhoid are surgical common disease, frequently-occurring disease, are clinically divided into internal hemorrhoid, external hemorrhoid, mixed hemorrhoid.Internal hemorrhoid is formed by hemorrhoid angular vein clump, occurs in above tooth trace, covers with mucosa, and the initial stage dashes forward people's rectum, and time can deviate from for a long time to outside anus.External hemorrhoid is formed by the outer venous plexus of hemorrhoid, occurs in below tooth trace and covers with skin, protrude from outside anus.By in hemorrhoid, outer venous plexus is formed mixed hemorrhoid with hemorrhoid, two kinds of hemorrhoid characteristics of holding concurrently.Hemorrhoid with hemorrhage, pain, swelling, humidity, pruritus, deviate from swelling for clinical manifestation.In treatment most based on conservative treatment, severe patient needs operative treatment.But operation wound is large, postoperative pain, wound healing time are long.
Summary of the invention
In order to solve above-mentioned technical problem, the invention provides a kind of Chinese medicine for hemorrhoid and preparation method thereof.
The present invention is realized by following technical scheme:
For a Chinese medicine for hemorrhoid, be made up of the raw material of Chinese medicine medicine of following weight portion:
To wash the dishes leaf 15-25 part, Rhizoma Angiopteridis Fokiensis 8-16 part, Herba Sedi 8-16 part, Cortex Phellodendri 8-16 part, Rhizoma Coptidis 3-9 part, Radix Angelicae Sinensis 8-16 part, Fructus Forsythiae 8-16 part, Natrii Sulfas 3-9 part, Alumen 3-9 part, Spina Gleditsiae 3-9 part, Radix Gentianae Macrophyllae 6-12 part, Catharsii molossi 3-9 part.
Preferably, the above-mentioned Chinese medicine for hemorrhoid, be made up of the raw material of Chinese medicine medicine of following weight portion:
To wash the dishes leaf 18-22 part, Rhizoma Angiopteridis Fokiensis 10-14 part, Herba Sedi 10-14 part, Cortex Phellodendri 10-14 part, Rhizoma Coptidis 5-7 part, Radix Angelicae Sinensis 10-14 part, Fructus Forsythiae 10-14 part, Natrii Sulfas 5-7 part, Alumen 5-7 part, Spina Gleditsiae 5-7 part, Radix Gentianae Macrophyllae 8-10 part, Catharsii molossi 5-7 part.
Preferred, the above-mentioned Chinese medicine for hemorrhoid, be made up of the raw material of Chinese medicine medicine of following weight portion:
To wash the dishes 20 parts, leaf, Rhizoma Angiopteridis Fokiensis 12 parts, Herba Sedi 12 parts, Cortex Phellodendri 12 parts, Rhizoma Coptidis 6 parts, Radix Angelicae Sinensis 12 parts, Fructus Forsythiae 12 parts, 6 parts, Natrii Sulfas, Alumen 6 parts, Spina Gleditsiae 6 parts, Radix Gentianae Macrophyllae 9 parts, Catharsii molossi 6 parts.
The above-mentioned Chinese medicine for hemorrhoid, the dosage form of this Chinese medicine is external wash liquid.
The above-mentioned Chinese medicine external washing liquid preparation method for hemorrhoid, comprises the steps:
A, takes various raw material according to required weight portion;
B, by Radix Angelicae Sinensis, Fructus Forsythiae, Spina Gleditsiae, Radix Gentianae Macrophyllae water vapour distillation volatile oil, the another device of the aqueous solution after distillation is collected;
C, by the medicinal residues after the leaf that washes the dishes, Rhizoma Angiopteridis Fokiensis, Herba Sedi, Cortex Phellodendri, Rhizoma Coptidis, Catharsii molossi and above-mentioned distillating extracting oil, decoct with water extraction secondary, first time adds injection volume 4-6 times amount soak by water 1.5-2.5 hour, second time adds injection volume 2-4 times amount soak by water 1-2 hour, collecting decoction, filters; Filtrate 60 DEG C is concentrated into the concentrated solution that relative density is 1.21 ~ 1.24, lets cool, and adds ethanol and reaches 80% to alcohol content, stir evenly, and room temperature leaves standstill 12 hours, filters; Filtrate 60 DEG C is reclaimed ethanol and is concentrated into relative density is 1.04 ~ 1.08, obtains concentrated solution, for subsequent use;
Aqueous solution after d, step a obtain distillation mixes with the concentrated solution of step b, adds Natrii Sulfas, Alumen, with adding with stirring; Add water and be adjusted to 2000 parts, filter, sterilizing, to obtain final product.
Above-mentioned in the Chinese medicine external washing liquid preparation method of hemorrhoid, decocting with water first time in process amount of water in described step c is 5 times of injection volume, decocts 2 hours; Second time amount of water is 3 times of injection volume, decocts 1 hour.
The above-mentioned Chinese medicine external washing liquid preparation method for hemorrhoid, detailed step is as follows:
A, takes the leaf 20g that washes the dishes, Rhizoma Angiopteridis Fokiensis 12g, Herba Sedi 12g, Cortex Phellodendri 12g, Rhizoma Coptidis 6g, Radix Angelicae Sinensis 12g, Fructus Forsythiae 12g, Natrii Sulfas 6g, Alumen 6g, Spina Gleditsiae 6g, Radix Gentianae Macrophyllae 9g, Catharsii molossi 6g;
B, by Radix Angelicae Sinensis, Fructus Forsythiae, Spina Gleditsiae, Radix Gentianae Macrophyllae water vapour distillation volatile oil, the another device of the aqueous solution after distillation is collected;
C, by the medicinal residues after the leaf that washes the dishes, Rhizoma Angiopteridis Fokiensis, Herba Sedi, Cortex Phellodendri, Rhizoma Coptidis, Catharsii molossi and above-mentioned distillating extracting oil, decocts with water extraction secondary, first time adds injection volume 5 times amount soak by water 2 hours, second time adds injection volume 3 times amount soak by water 1.5 hours, collecting decoction, filters; Filtrate 60 DEG C is concentrated into the concentrated solution that relative density is 1.21 ~ 1.24, lets cool, and adds ethanol and reaches 80% to alcohol content, stir evenly, and room temperature leaves standstill 12 hours, filters; Filtrate 60 DEG C is reclaimed ethanol and is concentrated into relative density is 1.04 ~ 1.08, obtains concentrated solution, for subsequent use;
Aqueous solution after d, step a obtain distillation mixes with the concentrated solution of step b, adds Natrii Sulfas, Alumen, with adding with stirring; Add water and be adjusted to 2000ml, filter, sterilizing, to obtain final product.
The leaf that washes the dishes is Solanaceae nightshade Radix solani coagulantis tree SolanumverbascifoliumL., is used as medicine with root and leaf.Return liver, stomach warp, kidney, spleen, lung, urinary bladder channel.There is heat-clearing and toxic substances removing, effect of wind-expelling pain-stopping.Clinically be used for the accumulation of heat stagnation of QI, epigastric pain; Rheumatic arthralgia, treating swelling and pain by traumatic injury.
Herba Sedi is the dry herb of crassulaceae plants Herba Sedi SedumsarmentosumBunge, has another name called mountain and protects flower, HERBA SEDI SARMENTOSI, Bermuda grass, Herba Sedi Multicaulis, Semen Benincasae grass, SANYE Herba Sedi Linearis, white Scolopendra, DIWUGONG grass, heronsbill, in vain opening, Herba Sedi Sarmentosi, Canis familiaris L. tooth lobe.Return Liver Channel, gallbladder meridian, small intestine meridian.There is eliminating damp-heat, effect of removing toxic substances.Clinically be used for jaundice due to damp-heat, dysuria, carbuncle skin infection, acute hepatitis, chronic hepatitis.
Rhizoma Angiopteridis Fokiensis have another name called Ungula Bovis seu Bubali labor, Horse hoof tree, Flos Nelumbinis, Herba Asari, Horse hoof Radix Aconiti Lateralis Preparata, kwan-yin seat lotus, Microsorium dilatatum (Bedd.) Sledge, Zantedeschia aethiopica Spreng., Horse hoof wind, goat hoof, Fujian lotus throne Herba pteridii latiusculi, mountain Hepar Sus domestica, great Feng Wei, cattle footprint, Bauhinia purpurea, cross hungry grass, be the rhizome of Angiopteridaceae plant Fujian kwan-yin seat lotus AngiopterisfokiensisHieron..Bitter; Cold; Cool, GUIXIN; Lung meridian, has clearing away heat and cooling blood; Hemostasis by removing blood stasis; Effect that analgesia is calmed the nerves.Clinically be mainly used in mumps; Carbuncle sore tumefacting virus; Venom; Treating swelling and pain by traumatic injury; Traumatic hemorrhage; Metrorrhagia; Acute mastitis; Rheumatic arthralgia; Puerperal abdonimal pain; Vexed insomnia.
Catharsii molossi is the dry Scorpio of coleoptera Scarabaeidae insecticide Catharsii molossi CatharsiusmolossusL..Salty, cold.Nontoxic.There is removing toxic substances, detumescence, effect of relieving constipation.Clinically be used for sore swollen toxin, anal fistula, constipation.
Other Cortex Phellodendri, Rhizoma Coptidis, Radix Angelicae Sinensis, Fructus Forsythiae, Natrii Sulfas, Alumen, Spina Gleditsiae, Radix Gentianae Macrophyllae are Chinese Pharmacopoeia 2010 editions medical materials recorded.
The usage and dosage of lotion of medication of the present invention is: boil temperature with the lotion of medication of the present invention of 20% concentration (namely getting this product 100ml warm water to 500ml, mixing) and smoke and wash anus position; Or with irrigator, the lotion of medication of the present invention of 50% concentration is delivered to deep rectum flushing anus.2-3 time on the one 10 days is a course for the treatment of.
Chinese medicine for hemorrhoid of the present invention, has heat clearing and damp drying, removing toxic substances and promoting subsidence of swelling, cooling blood for hemostasis, effect of promoting blood circulation and stopping pain, for various types of hemorrhoid.
Chinese medicine fumigation and washing is one of important external treatment of traditional Chinese medical science anorectal surgical, it is the traditional method for the treatment of hemorrhoid, fumigation and wash method refers to borrows the medicine vapour of transpiration to smoke affected part, again by affected part demibain in medicinal liquid, its efficacy of a drug and heating power is relied on to directly act on pathological change of anorectal position, make this place's space between skin and muscles dredging, QI and blood is smooth, thus reaches heat clearing and damp drying, promoting blood circulation and detumescence, analgesic hemostatic, convergence itching-relieving efficacies.There is special effect to treatment skin infection, and have no side effect.
Chinese medicine is thought, the generation of hemorrhoid disease is mostly by eating and drinking without temperance, rheumatism downward attack by pathogenic heat large intestine, and pyretic toxicity pents up, heat in blood dryness of the intestine, and poly-not the faling apart of knot forms.Chinese medicine for hemorrhoid of the present invention, compatibility is reasonable, and prescription is precise and appropriate.Full side has heat clearing and damp drying, removing toxic substances and promoting subsidence of swelling, cooling blood for hemostasis, effect of promoting blood circulation and stopping pain, and wash the dishes in side leaf, Rhizoma Angiopteridis Fokiensis, Herba Sedi, Cortex Phellodendri, Rhizoma Coptidis, Fructus Forsythiae, Spina Gleditsiae, Radix Gentianae Macrophyllae heat-clearing and toxic substances removing, and dampness is subsided a swelling, purging heat to relax the bowels, removing toxicity for eliminating carbuncles; Natrii Sulfas purges heat, and moisturizes, softening the hard mass, and external can control all kinds of skin infection carbuncle, has blood in stool; Herba Sedi cooling blood for hemostasis; Radix Angelicae Sinensis, Catharsii molossi promoting blood circulation to remove obstruction in the collateral, eliminating stasis to stop pain; Alumen convergence is astringent or styptic treatment for spontaneous sweating.Take a broad view of full side, medication is precise and appropriate, and compatibility is rigorous, and all medicines share, and hit pathogenesis, plays effect of heat clearing and damp drying, promoting blood circulation to remove blood stasis, reducing swelling and alleviating pain altogether.For various types of hemorrhoid, with the passing of time it be applicable to the course of disease, the patient of recurrent exerbation, and curative effect is better more outstanding.
The invention has the advantages that:
(1) the invention provides a kind of Chinese medicine for hemorrhoid newly, meet clinical needs.
(2) Chinese drug preparation that treatment is used for hemorrhoid is become washing liquid by the present invention, easy to use, patient's no pain, avoids the shortcoming that operation wound is large, postoperative pain, wound healing time are long.
(3) clinical test results shows, the Chinese medicine for hemorrhoid of the present invention, 1 the course for the treatment of obvious effective rate up to 48.81%, and matched group cure rate only has 26.92%, and both have significant difference (p < 0.01); 1 the course for the treatment of total effective rate up to 95.23%, and matched group effective percentage only has both 46.15% and has significant difference (p < 0.01).
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further described, so that those skilled in the art more understands the present invention, but does not therefore limit the present invention.
Embodiment 1
Prescription: the leaf 20g that washes the dishes, Rhizoma Angiopteridis Fokiensis 12g, Herba Sedi 12g, Cortex Phellodendri 12g, Rhizoma Coptidis 6g, Radix Angelicae Sinensis 12g, Fructus Forsythiae 12g, Natrii Sulfas 6g, Alumen 6g, Spina Gleditsiae 6g, Radix Gentianae Macrophyllae 9g, Catharsii molossi 6g.
Preparation method:
A, takes the leaf 20g that washes the dishes, Rhizoma Angiopteridis Fokiensis 12g, Herba Sedi 12g, Cortex Phellodendri 12g, Rhizoma Coptidis 6g, Radix Angelicae Sinensis 12g, Fructus Forsythiae 12g, Natrii Sulfas 6g, Alumen 6g, Spina Gleditsiae 6g, Radix Gentianae Macrophyllae 9g, Catharsii molossi 6g;
B, by Radix Angelicae Sinensis, Fructus Forsythiae, Spina Gleditsiae, Radix Gentianae Macrophyllae water vapour distillation volatile oil, the another device of the aqueous solution after distillation is collected;
C, by the medicinal residues after the leaf that washes the dishes, Rhizoma Angiopteridis Fokiensis, Herba Sedi, Cortex Phellodendri, Rhizoma Coptidis, Catharsii molossi and above-mentioned distillating extracting oil, decocts with water extraction secondary, first time adds injection volume 5 times amount soak by water 2 hours, second time adds injection volume 3 times amount soak by water 1.5 hours, collecting decoction, filters; Filtrate 60 DEG C is concentrated into the concentrated solution that relative density is 1.21 ~ 1.24, lets cool, and adds ethanol and reaches 80% to alcohol content, stir evenly, and room temperature leaves standstill 12 hours, filters; Filtrate 60 DEG C is reclaimed ethanol and is concentrated into relative density is 1.04 ~ 1.08, obtains concentrated solution, for subsequent use;
Aqueous solution after d, step a obtain distillation mixes with the concentrated solution of step b, adds Natrii Sulfas, Alumen, with adding with stirring; Add water and be adjusted to 2000ml, filter, sterilizing, to obtain final product.
Embodiment 2
Prescription:
To wash the dishes 18 parts, leaf, Rhizoma Angiopteridis Fokiensis 14 parts, Herba Sedi 10 parts, Cortex Phellodendri 14 parts, Rhizoma Coptidis 5 parts, Radix Angelicae Sinensis 14 parts, Fructus Forsythiae 10 parts, 7 parts, Natrii Sulfas, Alumen 5 parts, Spina Gleditsiae 7 parts, Radix Gentianae Macrophyllae 8 parts, Catharsii molossi 7 parts.
Preparation method:
A, takes various raw material according to required weight portion;
B, by Radix Angelicae Sinensis, Fructus Forsythiae, Spina Gleditsiae, Radix Gentianae Macrophyllae water vapour distillation volatile oil, the another device of the aqueous solution after distillation is collected;
C, by the medicinal residues after the leaf that washes the dishes, Rhizoma Angiopteridis Fokiensis, Herba Sedi, Cortex Phellodendri, Rhizoma Coptidis, Catharsii molossi and above-mentioned distillating extracting oil, decocts with water extraction secondary, first time adds injection volume 4 times amount soak by water 1.5 hours, second time adds injection volume 2 times amount soak by water 1 hour, collecting decoction, filters; Filtrate 60 DEG C is concentrated into the concentrated solution that relative density is 1.21 ~ 1.24, lets cool, and adds ethanol and reaches 80% to alcohol content, stir evenly, and room temperature leaves standstill 12 hours, filters; Filtrate 60 DEG C is reclaimed ethanol and is concentrated into relative density is 1.04 ~ 1.08, obtains concentrated solution, for subsequent use;
Aqueous solution after d, step a obtain distillation mixes with the concentrated solution of step b, adds Natrii Sulfas, Alumen, with adding with stirring; Add water and be adjusted to 2000 parts, filter, sterilizing, to obtain final product.
Embodiment 3
Prescription: 22 parts, the leaf that washes the dishes, Rhizoma Angiopteridis Fokiensis 10 parts, Herba Sedi 14 parts, Cortex Phellodendri 10 parts, Rhizoma Coptidis 7 parts, Radix Angelicae Sinensis 10 parts, Fructus Forsythiae 14 parts, 5 parts, Natrii Sulfas, Alumen 7 parts, Spina Gleditsiae 5 parts, Radix Gentianae Macrophyllae 10 parts, Catharsii molossi 5 parts.
Preparation method:
A, takes various raw material according to required weight portion;
B, by Radix Angelicae Sinensis, Fructus Forsythiae, Spina Gleditsiae, Radix Gentianae Macrophyllae water vapour distillation volatile oil, the another device of the aqueous solution after distillation is collected;
C, by the medicinal residues after the leaf that washes the dishes, Rhizoma Angiopteridis Fokiensis, Herba Sedi, Cortex Phellodendri, Rhizoma Coptidis, Catharsii molossi and above-mentioned distillating extracting oil, decocts with water extraction secondary, first time adds injection volume 6 times amount soak by water 2.5 hours, second time adds injection volume 4 times amount soak by water 2 hours, collecting decoction, filters; Filtrate 60 DEG C is concentrated into the concentrated solution that relative density is 1.21 ~ 1.24, lets cool, and adds ethanol and reaches 80% to alcohol content, stir evenly, and room temperature leaves standstill 12 hours, filters; Filtrate 60 DEG C is reclaimed ethanol and is concentrated into relative density is 1.04 ~ 1.08, obtains concentrated solution, for subsequent use;
Aqueous solution after d, step a obtain distillation mixes with the concentrated solution of step b, adds Natrii Sulfas, Alumen, with adding with stirring; Add water and be adjusted to 2000 parts, filter, sterilizing, to obtain final product.
Embodiment 4
Prescription:
To wash the dishes 25 parts, leaf, Rhizoma Angiopteridis Fokiensis 8 parts, Herba Sedi 16 parts, Cortex Phellodendri 8 parts, Rhizoma Coptidis 9 parts, Radix Angelicae Sinensis 8 parts, Fructus Forsythiae 16 parts, 3 parts, Natrii Sulfas, Alumen 9 parts, Spina Gleditsiae 3 parts, Radix Gentianae Macrophyllae 12 parts, Catharsii molossi 3 parts.
Preparation method is with embodiment 1.
Embodiment 5
Prescription:
To wash the dishes 15 parts, leaf, Rhizoma Angiopteridis Fokiensis 16 parts, Herba Sedi 8 parts, Cortex Phellodendri 16 parts, Rhizoma Coptidis 3 parts, Radix Angelicae Sinensis 16 parts, Fructus Forsythiae 8 parts, 9 parts, Natrii Sulfas, Alumen 3 parts, Spina Gleditsiae 9 parts, Radix Gentianae Macrophyllae 6 parts, Catharsii molossi 9 parts.
Preparation method is with embodiment 1.
Carried out clinical pharrnacokinetics test to the preparation of embodiments of the invention l, result is as follows:
All cases all come self-Out-patient Department and inpatient.The case 11O example meeting inclusive criteria is divided into two groups according to randomized, double-blind principle, treatment group 84 example, man 26 example, female 58 example; 21 ~ 73 years old age, average 52.45 ± 3.32 years old; The most elder of the course of disease 40 years, the shortest 6 months, average 21.24 ± 2.45 years.Matched group 26 example, male 1O example, female 16 example; 22 ~ 69 years old age, average 51.41 ± 2.22 years old; The most elder of the course of disease 36 years, the shortest 3 months, average 22.72 ± 2.5O.Two groups of there are no significant in sex, age, course of disease distribution etc. differences, have comparability (P>0.05).
The all cases of inclusive criteria meet " traditional Chinese medical science anorectum department disease Standardization of diagnosis and curative effect " l_2J of nineteen ninety-five State Administration of Traditional Chinese Medicine's promulgation, signature Informed Consent Form.Without Drug therapy in patient 1 month, non-row operative treatment in 6 months.
Exclusion standard I degree internal hemorrhoid; Gestation and women breast-feeding their children; Suffer from vitals disease, the psychiatric patients such as the serious heart, brain, liver, kidney; Suffer from anal fistula, proctoptosis, rectal polyp, anal papilla tumor, other anal and intestinal disease such as colorectal carcinoma, colitis; Meet above-mentioned diagnostic criteria but the person that needs operative treatment.
Therapeutic Method treatment group: adopt the Chinese medicinal lotion prepared of the embodiment of the present invention, (namely getting this product 100ml warm water to 500ml, mixing) is boiled temperature and is smoked and wash anus position, each 15 minutes, 2 times on the one.Attention: first should clean affected part by warm water before fumigation and wash method, and then first smoke with medicine juice and wash afterwards.Matched group with PP liquid (1:5000 potassium permanganate solution), the same treatment group of usage.Two groups was all 1 course for the treatment of with 10 days, and 1 course for the treatment of terminates rear observe the curative effect.
Criterion of therapeutical effect, according to nineteen ninety-five " traditional Chinese medical science anorectum department disease Standardization of diagnosis and curative effect " hemorrhoid symptom efficacy assessment standard, is formulated symptom and sign and is quantized
Standard.Curative effect index is pain, edema, hemorrhage, sepage, erosion, deviate from, and point 4 grades of point systems are scored: 0 point asymptomatic, and 1 point slight, 2 points of moderates, 3 points of severes.Formulate with reference to " traditional Chinese medical science anorectum department disease Standardization of diagnosis and curative effect ".Effective: symptom is obviously improved, to deviate from, the internal hemorrhoid of incarceration retraction and anus edge edema, thrombosis mass reduction degree >=2/3; Effective: symptom is improved, deviate from, the internal hemorrhoid of incarceration retraction and anus edge edema and thrombosis absorb and reach 1/3 ~ 2/3; Invalid: symptom is not improved, deviate from internal hemorrhoid and anus edge edema, the thrombosis lump contracting <1/3 of incarceration.
Statistical method adopts the process of SPSS13.0 statistical analysis software, and measurement data adopts t inspection, and efficacy analysis Ridit checks.Therapeutic outcome two groups of Comparison of therapeutic are in table 1.
Table 1 liang group Comparison of therapeutic (example)
Group | Number of cases | Effective | Effectively | Invalid | Obvious effective rate (%) | Total effective rate (%) |
Treatment group | 84 | 41 | 39 | 4 | 48.81* | 95.23* |
Matched group | 26 | 7 | 5 | 16 | 26.92 | 46.15 |
Note: two groups are compared, and P<0.01, difference has statistical significance
Compared with matched group, the Chinese medicine for hemorrhoid of the present invention, 1 the course for the treatment of obvious effective rate up to 48.81%, and matched group cure rate only has 26.92%, and both have significant difference (p < 0.01); 1 the course for the treatment of total effective rate up to 95.23%, and matched group effective percentage only has both 46.15% and has significant difference (p < 0.01).
Claims (7)
1., for a Chinese medicine composition for hemorrhoid, be made up of the raw material of Chinese medicine medicine of following weight portion:
To wash the dishes leaf 15-25 part, Rhizoma Angiopteridis Fokiensis 8-16 part, Herba Sedi 8-16 part, Cortex Phellodendri 8-16 part, Rhizoma Coptidis 3-9 part, Radix Angelicae Sinensis 8-16 part, Fructus Forsythiae 8-16 part, Natrii Sulfas 3-9 part, Alumen 3-9 part, Spina Gleditsiae 3-9 part, Radix Gentianae Macrophyllae 6-12 part, Catharsii molossi 3-9 part.
2. the Chinese medicine composition for hemorrhoid according to claim 1, is characterized in that, is made up of the raw material of Chinese medicine medicine of following weight portion:
To wash the dishes leaf 18-22 part, Rhizoma Angiopteridis Fokiensis 10-14 part, Herba Sedi 10-14 part, Cortex Phellodendri 10-14 part, Rhizoma Coptidis 5-7 part, Radix Angelicae Sinensis 10-14 part, Fructus Forsythiae 10-14 part, Natrii Sulfas 5-7 part, Alumen 5-7 part, Spina Gleditsiae 5-7 part, Radix Gentianae Macrophyllae 8-10 part, Catharsii molossi 5-7 part.
3. the Chinese medicine composition for hemorrhoid according to claim 2, is characterized in that, is made up of the raw material of Chinese medicine medicine of following weight portion:
To wash the dishes 20 parts, leaf, Rhizoma Angiopteridis Fokiensis 12 parts, Herba Sedi 12 parts, Cortex Phellodendri 12 parts, Rhizoma Coptidis 6 parts, Radix Angelicae Sinensis 12 parts, Fructus Forsythiae 12 parts, 6 parts, Natrii Sulfas, Alumen 6 parts, Spina Gleditsiae 6 parts, Radix Gentianae Macrophyllae 9 parts, Catharsii molossi 6 parts.
4. the Chinese medicine composition for hemorrhoid according to claim 1 or 2 or 3, is characterized in that, the dosage form of this Chinese medicine is external wash liquid.
5. the preparation method of the Chinese medicine composition for hemorrhoid according to claim 1, comprises the steps:
A, takes various raw material according to required weight portion;
B, by Radix Angelicae Sinensis, Fructus Forsythiae, Spina Gleditsiae, Radix Gentianae Macrophyllae water vapour distillation volatile oil, the another device of the aqueous solution after distillation is collected;
C, by the medicinal residues after the leaf that washes the dishes, Rhizoma Angiopteridis Fokiensis, Herba Sedi, Cortex Phellodendri, Rhizoma Coptidis, Catharsii molossi and above-mentioned distillating extracting oil, decoct with water extraction secondary, first time adds injection volume 4-6 times amount soak by water 1.5-2.5 hour, second time adds injection volume 2-4 times amount soak by water 1-2 hour, collecting decoction, filters; Filtrate 60 DEG C is concentrated into the concentrated solution that relative density is 1.21 ~ 1.24, lets cool, and adds ethanol and reaches 80% to alcohol content, stir evenly, and room temperature leaves standstill 12 hours, filters; Filtrate 60 DEG C is reclaimed ethanol and is concentrated into relative density is 1.04 ~ 1.08, obtains concentrated solution, for subsequent use;
Aqueous solution after d, step b obtain distillation mixes with the concentrated solution of step c, adds Natrii Sulfas, Alumen, with adding with stirring; Add water and be adjusted to 2000 parts, filter, sterilizing, to obtain final product.
6. the preparation method of the Chinese medicine composition for hemorrhoid according to claim 5, is characterized in that, decocting with water in process first time amount of water in described step c is 5 times of injection volume, decocts 2 hours; Second time amount of water is 3 times of injection volume, decocts 1 hour.
7. the preparation method of the Chinese medicine composition for hemorrhoid according to claim 5, detailed step is as follows:
A, takes the leaf 20g that washes the dishes, Rhizoma Angiopteridis Fokiensis 12g, Herba Sedi 12g, Cortex Phellodendri 12g, Rhizoma Coptidis 6g, Radix Angelicae Sinensis 12g, Fructus Forsythiae 12g, Natrii Sulfas 6g, Alumen 6g, Spina Gleditsiae 6g, Radix Gentianae Macrophyllae 9g, Catharsii molossi 6g;
B, by Radix Angelicae Sinensis, Fructus Forsythiae, Spina Gleditsiae, Radix Gentianae Macrophyllae water vapour distillation volatile oil, the another device of the aqueous solution after distillation is collected;
C, by the medicinal residues after the leaf that washes the dishes, Rhizoma Angiopteridis Fokiensis, Herba Sedi, Cortex Phellodendri, Rhizoma Coptidis, Catharsii molossi and above-mentioned distillating extracting oil, decocts with water extraction secondary, first time adds injection volume 5 times amount soak by water 2 hours, second time adds injection volume 3 times amount soak by water 1.5 hours, collecting decoction, filters; Filtrate 60 DEG C is concentrated into the concentrated solution that relative density is 1.21 ~ 1.24, lets cool, and adds ethanol and reaches 80% to alcohol content, stir evenly, and room temperature leaves standstill 12 hours, filters; Filtrate 60 DEG C is reclaimed ethanol and is concentrated into relative density is 1.04 ~ 1.08, obtains concentrated solution, for subsequent use;
Aqueous solution after d, step b obtain distillation mixes with the concentrated solution of step c, adds Natrii Sulfas, Alumen, with adding with stirring; Add water and be adjusted to 2000ml, filter, sterilizing, to obtain final product.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201310699246.8A CN103623122B (en) | 2013-12-19 | 2013-12-19 | A kind of Chinese medicine for hemorrhoid and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201310699246.8A CN103623122B (en) | 2013-12-19 | 2013-12-19 | A kind of Chinese medicine for hemorrhoid and preparation method thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
CN103623122A CN103623122A (en) | 2014-03-12 |
CN103623122B true CN103623122B (en) | 2015-11-18 |
Family
ID=50204806
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201310699246.8A Expired - Fee Related CN103623122B (en) | 2013-12-19 | 2013-12-19 | A kind of Chinese medicine for hemorrhoid and preparation method thereof |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN103623122B (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103933196B (en) * | 2014-03-14 | 2016-01-20 | 唐淑云 | A kind of Chinese medicine fuming-lotion for the treatment of hemorrhoid |
CN105168355A (en) * | 2015-10-10 | 2015-12-23 | 战三红 | Traditional Chinese medicine composition for treating haemorrhoids and preparation method of traditional Chinese medicine composition |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1331498C (en) * | 2005-11-18 | 2007-08-15 | 石训义 | Method for preparing piles-treating Chinese modicine |
CN103285154B (en) * | 2013-07-06 | 2014-05-07 | 刘建飞 | Traditional Chinese medicine preparation for treating haemorrhoids |
-
2013
- 2013-12-19 CN CN201310699246.8A patent/CN103623122B/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN103623122A (en) | 2014-03-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN102847063B (en) | Traditional Chinese medicinal composition for treating qi and blood deficiency blood stasis type diabetic feet, and its preparation method | |
CN102205026B (en) | Chinese medicinal composition for treating children chronic sinusitis and preparation method thereof | |
CN103623122B (en) | A kind of Chinese medicine for hemorrhoid and preparation method thereof | |
CN103446528B (en) | Chinese medicinal composition used for stopping pain and reducing swelling and preparation thereof | |
CN103599263B (en) | A kind of Chinese medicine for hemorrhoid and preparation method thereof | |
CN104840599A (en) | Medicine for treating ankylosing spondylitis | |
CN103330872B (en) | Method for preparing snake wound rehabilitation medicament | |
CN103417781B (en) | A kind of Chinese medicine for the treatment of surgical wound | |
CN103330873B (en) | Snake wound rehabilitation medicament | |
CN103638193B (en) | A kind of Chinese medicine for acne and preparation method thereof | |
CN105169294A (en) | Traditional Chinese medicine ointment for treating scapulohumeral periarthritis | |
CN103599477A (en) | Traditional Chinese medicinal composition for treating humid heat stagnation type chronic prostatitis | |
CN103736025A (en) | Tissue regeneration promoting plaster for traumatic injuries | |
CN102552784B (en) | Preparation method of traditional Chinese medicine for treating prostatitis caused by fire excess from yin deficiency | |
CN103520447A (en) | Externally used ointment suitable for anal fistula after operation | |
CN111686182B (en) | Chinese medicinal composition for removing blood stasis and relieving pain and preparation method thereof | |
CN104784285A (en) | Traditional Chinese medicine ointment for treating rosacea | |
CN104491526A (en) | Traditional Chinese medicine preparation for treating hemoptysis bronchiectasis | |
CN105497459A (en) | Traditional Chinese medicine preparation for treating woman leukorrheal diseases as well as preparation method and application of traditional Chinese medicine preparation | |
CN105663850A (en) | Traditional Chinese medicine composition for treating oral ulcer | |
CN105596584A (en) | Traditional Chinese medicine preparation special for local anesthesia and preparation method thereof | |
CN105434808A (en) | Traditional Chinese medicine composition for treating hemorrhoids and preparation method thereof | |
CN104306734A (en) | Plaster preparation for external use for treating diabetic gangrene and preparation method thereof | |
CN101757174B (en) | Medicinal composition with analgesic and anti-inflammatory effects | |
CN103479917B (en) | Traditional Chinese medicine composition for treating burns and scalds |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
CB03 | Change of inventor or designer information |
Inventor after: Liu Quanyuan Inventor after: Wang Chunjian Inventor after: Liu Quanyuan, Wang Chunjian, Cheng Wenna Inventor before: Zhou Xiaolong Inventor before: Wang Chunjian Inventor before: Zhou Xiao Jun, Chun Chun, Cheng Wenna |
|
COR | Change of bibliographic data | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
CF01 | Termination of patent right due to non-payment of annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20151118 Termination date: 20161219 |