CN103520017A - Wrinkle-removing, anti-ageing, skin-activating, restoring and whitening composition - Google Patents
Wrinkle-removing, anti-ageing, skin-activating, restoring and whitening composition Download PDFInfo
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- CN103520017A CN103520017A CN201310500055.4A CN201310500055A CN103520017A CN 103520017 A CN103520017 A CN 103520017A CN 201310500055 A CN201310500055 A CN 201310500055A CN 103520017 A CN103520017 A CN 103520017A
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Abstract
The invention discloses a wrinkle-removing, anti-ageing, skin-activating, restoring and whitening composition. The composition comprises the following components in percentage by weight: 15%-30% of hyaluronic acid, 25%-40% of collagen, 0.0001%-0.0009% of recombinant human epidermal growth factor, and 5%-20% of glycerol. Collagen can effectively inhibit generation of melanin and promote metabolism of skin tissue; hyaluronic acid can effectively nourish and moisturize skin, remove wrinkles and beautify looks; recombinant human epidermal growth factor can quicken dropping of senescent cells of a human body and promote reverse differentiation of the cells to generate young cells, can promote regeneration of subcutaneous collagen and recombination of fibrous tissue, improve skin elasticity and reduce skin sensitivity, and can make thick, flushing and expanding facial capillaries atrophy and get thinner and shallower, avoid pigmentation and remove facial toxin residues so as to achieve the efficacy of removing freckles, acne marks and wrinkles as well as tendering and whitening.
Description
Technical field
The present invention relates to cosmetics, especially relate to that a kind of reduce wrinkle is anti-ageing, the compositions of Cucumber Extract, reparation whitening.
Background technology
With advancing age, fibroblastic synthesis capability declines, iuntercellular mucopolysaccharide reduces, skin just can lose softness, elasticity and gloss, occur aging, the fibrous fracture of corium, lipoatrophy, sweat gland and smegma reduce simultaneously, make skin occur a series of catabiosis such as mottle, wrinkle.The color of skin is mainly that the melanic quantity, the distribution that according to Skin Cell, contain decide.Generally, skin-whitening agents is all active by restraint of tyrosinase or blocking-up tyrosine generates melanic oxidative pathway, thereby reduces the effect that melanic generation reaches skin whitening.The most mechanism of action of whitening and moistening skin product is in the market single, and just the generation by check melanin to be to reach whitening effect, and ignored Cucumber Extract, reduce wrinkle is anti-ageing, final effect is not ideal enough, causes consumer not to be satisfied with.
Summary of the invention
The object of the present invention is to provide a kind of formation that can efficiently suppress black, promote that the reduce wrinkle of skin metabolism is anti-ageing, the compositions of Cucumber Extract, reparation whitening.
The present invention adopts following technical scheme to realize: a kind of reduce wrinkle is anti-ageing, the compositions of Cucumber Extract, reparation whitening, in weight percentage, described compositions comprises following component: hyaluronic acid 15%～30%, collagen protein 25%～40%, recombinant human epidermal growth factor 0.0001%～0.0009%, glycerol 5%～20%.
As a kind of preferred version, in weight percentage, described compositions comprises following component: hyaluronic acid 20%～25%, collagen protein 30%～35%, recombinant human epidermal growth factor 0.0003%～0.0005%, glycerol 10%～15%.
As another kind of preferred version, in weight percentage, described compositions comprises following component: hyaluronic acid 22%, collagen protein 32%, recombinant human epidermal growth factor 0.0004%, glycerol 12%.
In said components, hyaluronic acid is a kind of acid mucopolysaccharide, and first the ophthalmology professor Meyer of Columbia Univ USA in 1934 etc. isolate this material from bovine vitreous body.Hyaluronic acid demonstrates multiple important physiological function with its unique molecular structure and physicochemical property in body, as lubricated joint, regulates the permeability of blood vessel wall, regulates protein, and Water-Electrolyte diffusion and running, promote wound healing etc.Particularly importantly, hyaluronic acid has special water retention, is the best material of occurring in nature moisture retention of finding at present, is called as desirable nature moisturizing factor.Human skin also contains a large amount of hyaluronic acids, ripe and the ageing process of skin also changes along with hyaluronic content and metabolism, it can improve skin-nourishing metabolism, make that skin is tender, smooth, wrinkle removing, increase elasticity, prevent aging, be again good Percutaneous absorption enhancer in moisturizing.
Collagen protein is a kind of structural protein of extracellular matrix, and GL-PP, is white in color, and contains a small amount of galactose and glucose, is the main component of extracellular matrix, accounts for 85% of collagen fiber solids.Collagen protein is ubiquitous a kind of high molecular weight protein in animal body, is mainly present in the connective tissue (bone, cartilage, skin, tendon, tough etc.) of animal, accounts for 25%～30% of mammalian body internal protein, is equivalent to 6% of body weight.To body and internal organs play support, protection, in conjunction with and form boundary every etc. effect.While being used for whitening and moistening skin product using it as active substance, can be spread to the deep layer of skin, the tyrosine that it contains and the competition of the tyrosine in skin, and be combined with the catalytic center of tryrosinase, thereby the generation of check melanin, makes the collagen protein increased activity in skin, keep the integrity of horny layer moisture and fibre structure, the metabolism that promotes skin histology, produces good moist moisturizing, effect wrinkles eliminating vanishing effect to skin.
Recombinant human epidermal growth factor by 53 aminoacid, formed micromolecule polypeptide, it is a kind of strong augmentor, it can stimulate epidermis, endotheliocyte, epithelial cell, fibroblast and angiogenesis, it can also promote the synthetic of the extracellular matrixs such as hyaluronic acid, fibronectin, glycoprotein and hydroxyproline simultaneously, therefore for can be used for treating the healing of skin burn, surgical wound, and traumatic corneal ulcer, corneal injury, chemical reagent burn cornea and corneal transplantation.1986, the foremost Nobel Prize of World Science circle evaluation committee, by blue ribbon-Nobel physiology and the Medicine of this annual life science, authorized American scientist Cohen.S professor and Levi.Montalcini professor, commended them in the outstanding contribution of making aspect discovery and research epidermal growth factor!
Glycerol, has another name called glycerol, is the simplest trihydroxy alcohol, is the most general wetting agent, can draw airborne moisture content to skin moisture-keeping, also the moisture content in skin can be pinned.
A kind of reduce wrinkle that the present invention proposes is anti-ageing, Cucumber Extract, repair the compositions of whitening, the wherein effectively generation of check melanin of component collagen protein, promote the metabolism of skin histology, hyaluronic acid can effectively moisten moisturizing skin, wrinkle removal beauty treatment, recombinant human epidermal growth factor can accelerate coming off of human senility cell and can make its contrary young cell that is divided into, can promote the regeneration of subcutaneous collagen protein and the restructuring of fibrous tissue, strengthen skin elasticity, reduce skin sensitivity degree, can make face thick, flushing, the blood capillary atrophy of expansion attenuates and shoals, avoid pigmentation, dispel facial the toxin remains, there is the light speckle seal of dispelling, the tender white effect of reduce wrinkle.
The specific embodiment
The compositions of, Cucumber Extract anti-ageing to a kind of reduce wrinkle of the present invention below in conjunction with specific embodiment, reparation whitening is described in further detail.
Embodiment 1
Reduce wrinkle is anti-ageing, a compositions for Cucumber Extract, reparation whitening, and in weight percentage, described compositions comprises following component: hyaluronic acid 22%, collagen protein 32%, recombinant human epidermal growth factor 0.0004%, glycerol 12%.
Take that to prepare compositions described in a hectogram be example, getting respectively 22 grams of hyaluronic acids, 32 grams of collagen protein, 0.0004 gram of recombinant human epidermal growth factor and 12 grams of glycerol joins in 30 grams of pure water, with high speed dispersor, it is fully dissolved, with pure water, be settled to 100 grams again, be uniformly mixed, then make milky lotion according to a conventional method.
Embodiment 2
Reduce wrinkle is anti-ageing, a compositions for Cucumber Extract, reparation whitening, and in weight percentage, described compositions comprises following component: hyaluronic acid 15%, collagen protein 25%, recombinant human epidermal growth factor 0.0009%, glycerol 20%.
Take that to prepare compositions described in a hectogram be example, getting respectively 15 grams of hyaluronic acids, 25 grams of collagen protein, 0.0009 gram of recombinant human epidermal growth factor and 20 grams of glycerol joins in 35 grams of pure water, with high speed dispersor, it is fully dissolved, with pure water, be settled to 100 grams again, be uniformly mixed, then make milky lotion according to a conventional method.
Embodiment 3
Reduce wrinkle is anti-ageing, a compositions for Cucumber Extract, reparation whitening, and in weight percentage, described compositions comprises following component: hyaluronic acid 20%, collagen protein 30%, recombinant human epidermal growth factor 0.0005%, glycerol 15%.
Take that to prepare compositions described in a hectogram be example, getting respectively 20 grams of hyaluronic acids, 30 grams of collagen protein, 0.0005 gram of recombinant human epidermal growth factor and 15 grams of glycerol joins in 30 grams of pure water, with high speed dispersor, it is fully dissolved, with pure water, be settled to 100 grams again, be uniformly mixed, then make milky lotion according to a conventional method.
Embodiment 4
Reduce wrinkle is anti-ageing, a compositions for Cucumber Extract, reparation whitening, and in weight percentage, described compositions comprises following component: hyaluronic acid 25%, collagen protein 35%, recombinant human epidermal growth factor 0.0003%, glycerol 10%.
Take that to prepare compositions described in a hectogram be example, getting respectively 25 grams of hyaluronic acids, 35 grams of collagen protein, 0.0003 gram of recombinant human epidermal growth factor and 10 grams of glycerol joins in 25 grams of pure water, with high speed dispersor, it is fully dissolved, with pure water, be settled to 100 grams again, be uniformly mixed, then make milky lotion according to a conventional method.
Embodiment 5
Reduce wrinkle is anti-ageing, a compositions for Cucumber Extract, reparation whitening, and in weight percentage, described compositions comprises following component: hyaluronic acid 28%, collagen protein 36%, recombinant human epidermal growth factor 0.0002%, glycerol 6%.
Take that to prepare compositions described in a hectogram be example, getting respectively 28 grams of hyaluronic acids, 36 grams of collagen protein, 0.0002 gram of recombinant human epidermal growth factor and 6 grams of glycerol joins in 25 grams of pure water, with high speed dispersor, it is fully dissolved, with pure water, be settled to 100 grams again, be uniformly mixed, then make milky lotion according to a conventional method.
Embodiment 6
Reduce wrinkle is anti-ageing, a compositions for Cucumber Extract, reparation whitening, and in weight percentage, described compositions comprises following component: hyaluronic acid 30%, collagen protein 40%, recombinant human epidermal growth factor 0.0001%, glycerol 5%.
Take that to prepare compositions described in a hectogram be example, getting respectively 30 grams of hyaluronic acids, 40 grams of collagen protein, 0.0001 gram of recombinant human epidermal growth factor and 5 grams of glycerol joins in 20 grams of pure water, with high speed dispersor, it is fully dissolved, with pure water, be settled to 100 grams again, be uniformly mixed, then make milky lotion according to a conventional method.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, all any modifications of doing within the spirit and principles in the present invention, be equal to and replace and improvement etc., within all should being included in protection scope of the present invention.
Claims (3)
1. a compositions for anti-ageing, the Cucumber Extract of reduce wrinkle, reparation whitening, is characterized in that, in weight percentage, described compositions comprises following component: hyaluronic acid 15%～30%, collagen protein 25%～40%, recombinant human epidermal growth factor 0.0001%～0.0009%, glycerol 5%～20%.
2. compositions according to claim 1, is characterized in that, in weight percentage, described compositions comprises following component: hyaluronic acid 20%～25%, collagen protein 30%～35%, recombinant human epidermal growth factor 0.0003%～0.0005%, glycerol 10%～15%.
3. compositions according to claim 2, is characterized in that, in weight percentage, described compositions comprises following component: hyaluronic acid 22%, collagen protein 32%, recombinant human epidermal growth factor 0.0004%, glycerol 12%.
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| CN201310500055.4A CN103520017A (en) | 2013-10-22 | 2013-10-22 | Wrinkle-removing, anti-ageing, skin-activating, restoring and whitening composition |
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| CN201310500055.4A CN103520017A (en) | 2013-10-22 | 2013-10-22 | Wrinkle-removing, anti-ageing, skin-activating, restoring and whitening composition |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106344422A (en) * | 2016-10-21 | 2017-01-25 | 广州赛莱拉干细胞科技股份有限公司 | Beautifying preparation and preparation method thereof |
| CN109106679A (en) * | 2018-11-01 | 2019-01-01 | 独角兽生命科学股份公司 | Anti-ageing Regeneration and Repair liquid of skin and preparation method thereof |
| CN110339082A (en) * | 2019-07-12 | 2019-10-18 | 广东美康纳米生物科技有限公司 | A kind of composition and its preparation method and application with skin-care effect |
| CN113143791A (en) * | 2021-05-17 | 2021-07-23 | 威海萨维诺健康管理有限公司 | Compound injection with whitening and anti-aging effects and preparation method thereof |
| CN113274310A (en) * | 2021-06-04 | 2021-08-20 | 华熙生物科技股份有限公司 | New application of zinc hyaluronate in repairing skin injury, composition and skin external preparation thereof |
| CN116270301A (en) * | 2023-02-20 | 2023-06-23 | 杭州欣创医疗器械有限公司 | Hyaluronic acid skin protection composition and preparation method thereof |
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| CN102258445A (en) * | 2011-07-14 | 2011-11-30 | 陈俊杰 | SOD (superoxide dismutase) collagen peptide facial-beautification anti-aging agent |
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| CN103271837A (en) * | 2013-06-07 | 2013-09-04 | 王迎峰 | Formula and preparation method for bioactive cosmetic |
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- 2013-10-22 CN CN201310500055.4A patent/CN103520017A/en active Pending
Patent Citations (4)
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| CN101884602A (en) * | 2010-03-03 | 2010-11-17 | 孙杰 | A kind of cosmetic formulations of skin-care, defect-repairing, anti-aging and winkle-removing |
| CN102258445A (en) * | 2011-07-14 | 2011-11-30 | 陈俊杰 | SOD (superoxide dismutase) collagen peptide facial-beautification anti-aging agent |
| CN102349867A (en) * | 2011-11-02 | 2012-02-15 | 广州舒泰生物技术有限公司 | Water-replenishing repairing cosmetic as well as preparation method and application thereof |
| CN103271837A (en) * | 2013-06-07 | 2013-09-04 | 王迎峰 | Formula and preparation method for bioactive cosmetic |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106344422A (en) * | 2016-10-21 | 2017-01-25 | 广州赛莱拉干细胞科技股份有限公司 | Beautifying preparation and preparation method thereof |
| CN109106679A (en) * | 2018-11-01 | 2019-01-01 | 独角兽生命科学股份公司 | Anti-ageing Regeneration and Repair liquid of skin and preparation method thereof |
| CN110339082A (en) * | 2019-07-12 | 2019-10-18 | 广东美康纳米生物科技有限公司 | A kind of composition and its preparation method and application with skin-care effect |
| CN113143791A (en) * | 2021-05-17 | 2021-07-23 | 威海萨维诺健康管理有限公司 | Compound injection with whitening and anti-aging effects and preparation method thereof |
| CN113274310A (en) * | 2021-06-04 | 2021-08-20 | 华熙生物科技股份有限公司 | New application of zinc hyaluronate in repairing skin injury, composition and skin external preparation thereof |
| CN116270301A (en) * | 2023-02-20 | 2023-06-23 | 杭州欣创医疗器械有限公司 | Hyaluronic acid skin protection composition and preparation method thereof |
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Application publication date: 20140122 |