CN103386066B - Medicine used for treating hernia and preparation method thereof - Google Patents
Medicine used for treating hernia and preparation method thereof Download PDFInfo
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- CN103386066B CN103386066B CN201310309627.0A CN201310309627A CN103386066B CN 103386066 B CN103386066 B CN 103386066B CN 201310309627 A CN201310309627 A CN 201310309627A CN 103386066 B CN103386066 B CN 103386066B
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Abstract
The invention discloses a medicine used for treating hernia and a preparation method thereof. The medicine is prepared mainly from pericarpium citri reticulatae viride, pericarpium citri reticulatae, laminaria, fennel, calami rhizoma, rhizoma corydalis and szechwan chinaberry fruit according to a certain weight ratio. The medicine has functions of clearing away heat and toxic materials, regulating qi circulation and tonifying spleen, eliminating cold and relieving pain, and promoting blood circulation to remove blood stasis. The medicine has rapid effectiveness, good curative effects and high cure rate when being used for treating the hernia.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of hernia and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Hernia, namely tissue or an organ part have left original position, enter another position by human interstitial, defect or weak part.The formation of hernia and the body constitution of patient have very large relation, be mostly due to cough, sneeze, overexertion, abdominal part overfertilization, firmly defecation, forepart pregnant women, children's excessively cry, the reason such as old stomach wall intensity degeneration, intraperitoneal is caused to produce negative pressure, intraperitoneal air pressure is caused to increase, force Intraabdominal free internal organs such as: internal organs such as testis, small intestinal, caecum, omentum majus, bladder, ovary, fallopian tube to see that hole is just bored, enter another position by original position by human normal or abnormal weak spot or defect, hole.At present, Western medicine effectively cannot control hernia, and has more side effect, and therefore, people exist very large demand to the Chinese medicine of effectively treating hernia.
Summary of the invention
The present inventor, according to the research of theory of Chinese medical science and clinical test repeatedly and checking, finally have found the medicine of effectively treatment hernia, thus completes the present invention.
Object of the present invention is just to provide a kind of composition of medicine effectively can treating hernia.
Another object of the present invention just there is provided the preparation method of this composition of medicine.
Medicine of the present invention selects Pericarpium Citri Reticulatae Viride, Pericarpium Citri Reticulatae, Thallus Laminariae (Thallus Eckloniae), Fructus Foeniculi, Rhizoma Acori Calami, Rhizoma Corydalis, Fructus Toosendan, Semen Citri Reticulatae, the Radix Aucklandiae, Rhizoma Cyperi, Cortex Cinnamomi, Rhizoma Alpiniae Officinarum medicine to combine, made by these drug regimens each efficacy of drugs produce synergism, thus effectively can treat the recurrence of hernia.Wherein select Pericarpium Citri Reticulatae Viride to be that tepor, enters liver, gallbladder meridian, has soothing the liver dispelling the stagnated QI, the function of eliminating stagnation expectorant because its nature and flavor toil, control breast side of body gastralgia, hernia, food stagnation, swelling of the breast, nodule in the breast, chronic malaria addiction block.Pericarpium Citri Reticulatae is selected to be that temperature, return lung, spleen channel, have regulating qi-flowing for strengthening spleen, the function of drying dampness to eliminate phlegm, controls fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm because its nature and flavor are bitter, pungent.Select Thallus Laminariae (Thallus Eckloniae) to be because its nature and flavor are salty, cold, enter stomach warp, have softening the hard mass, the function of row water, controls scrofula, and goiter is dysphagic, edema, painful and swollen testis, leukorrhagia.Select Fructus Foeniculi to be that temperature, returns liver,kidney,spleen, stomach warp, have dispersing cold for relieving pain, the function of regulating qi-flowing for harmonizing stomach because its nature and flavor are pungent, control colic of cold type stomachache, the testis swelling and hanging down of either of the testes, dysmenorrhea, few abdomen cold type of pain, distension and fullness in the abdomen, lack of appetite and vomiting, hydrocele of testis.Select Rhizoma Acori Calami to be that tepor, enters the heart, lung, stomach warp, have inducing resuscitation and resolving phlegm, ward off the function of dirty parasite killing because its nature and flavor are bitter, pungent, control sputum heap soil or fertilizer over and around the roots and close, obnubilation, chronic tracheitis, abdominal distention is suffered from abdominal pain, inappetence, enteritis, dysentery, rheumatic arthralgia, wound scabies.Rhizoma Corydalis is selected to be that temperature, enter liver, stomach warp, invigorate blood circulation, dissipating blood stasis, regulates the flow of vital energy, the function of pain relieving, controls all pains of trusted subordinate's waist knee joint, menoxenia , mass in the abdomen, metrorrhagia, puerperal blood faints, lochiorrhea, traumatic injury because its nature and flavor are worked hard.Select Fructus Toosendan to be because its nature and flavor are bitter, cold, poisonous, enter liver, stomach, small intestine meridian, have wet down heat, clearing away liver-fire, pain relieving, the function of parasite killing, controls epigastric pain with cold limbs due to adverseness of heat, hypochondriac pain, colic, abdominal pain due to worm stagnation.Semen Citri Reticulatae is selected to be that flat, nontoxic, enter liver, kidney channel, regulate the flow of vital energy, the function of pain relieving, controls hernia, painful and swollen testis, acute mastitis, lumbago, colicky pain of bladder because its nature and flavor are bitter.Select the Radix Aucklandiae to be that temperature, enters lung, liver, spleen channel, have promoting the circulation of QI to relieve pain, the function of warming middle-JIAO for easing the stomach, control the invasion by pathogenic cold stagnation of QI, chest and abdomen swelling and pain because its nature and flavor are worked hard, vomiting, has loose bowels, dysentery tenesmus, colic of cold type.Rhizoma Cyperi is selected to be because the pungent micro-hard work of its nature and flavor, flat, enter liver, tri-jiao channel, resolving depression of regulating the flow of vital energy, the function of pain relieving regulating menstruation, treating the liver discomfort in the stomach, depression of QI, breast abdomen distending pain over the hypochondrium, phlegm retention feeling of fullness, menoxenia, bleeding not during menses.Select Cortex Cinnamomi to be because its property acrid-sweet flavor, heat, enters kidney, spleen, urinary bladder channel, has complement sun, warming the spleen and stomach, removing accumulated cold, the function of promoting blood circulation, controls decline of the fire from the gate of life, cold extremities faint pulse, and YANG-depletion is collapsed, and stomachache is had loose bowels, colic of cold type renal mass, chills and pain of the waist and kness, amenorrhea and mass in the abdomen, carbuncle of yin nature, multiple abscess, and empty sun is more floating, heat in the upper and cold in the lower.Rhizoma Alpiniae Officinarum is selected to be that enter spleen, stomach warp, has stomach warming, dispels the wind, cold expelling, circulation of qi promoting, the function of pain relieving, and control taste invasion by pathogenic cold, coldness and pain in the epigastrium, vomiting is had loose bowels, dysphagia and regurgitation, dyspepsia, subtertian malaria, cold addiction because its property and flavor of peppery and warm.
The consumption of drug component of the present invention is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect within the scope of following weight
Pericarpium Citri Reticulatae Viride 8-12 gram of Pericarpium Citri Reticulatae 8-12 gram of Thallus Laminariae (Thallus Eckloniae) 10-20 gram
Fructus Foeniculi 10-20 gram of Rhizoma Acori Calami 8-12 gram of Rhizoma Corydalis 8-12 gram
Fructus Toosendan 10-20 gram of Semen Citri Reticulatae 10-20 gram of Radix Aucklandiae 8-12 gram
Rhizoma Cyperi 8-12 gram of Cortex Cinnamomi 8-12 gram of Rhizoma Alpiniae Officinarum 8-12 gram
Preferable amount is
Pericarpium Citri Reticulatae Viride 10 grams of Pericarpium Citri Reticulataes 10 grams of Thallus Laminariae (Thallus Eckloniae)s 15 grams
Fructus Foeniculi 15 grams of Rhizoma Acori Calami 10 grams of Rhizoma Corydalis 10 grams
Fructus Toosendan 15 grams of Semen Citri Reticulataes 15 grams of Radix Aucklandiae 10 grams
Rhizoma Cyperi 10 grams of Cortex Cinnamomis 10 grams of Rhizoma Alpiniae Officinarums 10 grams
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Pericarpium Citri Reticulatae Viride: pick clean impurity, be soaked in water, pull out, run through, section, dries;
2, Pericarpium Citri Reticulatae: get crude drug, the peel of removing impurity and blackening, wash quickly is clean, softens, shredding, dries or cold drying, sieve dedust bits;
3, Thallus Laminariae (Thallus Eckloniae): pick decontamination, rinses with water, is cut into wide silk, dries;
4, Fructus Foeniculi: get crude drug, removing impurity;
5, Rhizoma Acori Calami: get crude drug, removing reed clothing, impurity, clean, run through, cut sheet, cold drying;
6, Rhizoma Corydalis: pick decontamination, is soaked in water, and clean, solarization is dried in the air, and profit is even to inside and outside humidity, cuts into slices or smashes;
7, Fructus Toosendan: pick decontamination, cleans, and dries, grating or cleave in two;
8, Semen Citri Reticulatae: sieve dedust bits, pick clean impurity, clean, dry;
9, the Radix Aucklandiae: put by crude drug in whole in clear water and clean, pull out, moistening makes soft for 12-24 hours, section, dries;
10, Rhizoma Cyperi: pick decontamination, is ground into particle, winnow with a dustpan fine, soft fur and smalls;
11, Cortex Cinnamomi: pick clean impurity, scrape off rough bark, the used time smashes, or scrapes off rough bark, infiltrates a moment by warm water, and section, dries;
12, Rhizoma Alpiniae Officinarum: pick clean impurity, washing, slightly soaks, pulls out, run through, and section, dries.
Two, prepare
1, the Pericarpium Citri Reticulatae Viride of described weight, Pericarpium Citri Reticulatae, Thallus Laminariae (Thallus Eckloniae), Fructus Foeniculi, Rhizoma Acori Calami, Rhizoma Corydalis, Fructus Toosendan, Semen Citri Reticulatae, the Radix Aucklandiae, Rhizoma Cyperi, Cortex Cinnamomi, Rhizoma Alpiniae Officinarum crude drug are added 6 times of water gagings and soak, soak after 60 minutes, intense fire decocts boiling 20 minutes, use slow fire boiling again 30 minutes, filter first time decoction liquor.
2, add water the medicinal residues of filtration 4 times amount, and intense fire decocts boiling 10 minutes, then uses slow fire boiling 15 minutes, filters to obtain second time decoction liquor.
3, by twice decoction liquor mixing and stirring, then use slow fire boiling 10 minutes, decoction liquor be divided into 3 doses to take.
Medicine of the present invention has heat-clearing and toxic substances removing, regulating qi-flowing for strengthening spleen, cold expelling, circulation of qi promoting, and effect of pain relieving, is used for the treatment of hernia, short treating period, instant effect, non-relapse after healing, has no side effect.
Detailed description of the invention
Set forth the beneficial effect of medicine of the present invention further below by way of test example, these test examples include animal toxicity test report and the clinical observation material of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention
Get rabbit 20, male and female dual-purpose, body weight 2.0-2.5kg, divide two groups, often organize 10, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, every day 2 times, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation material of [test example 2] Drug therapy hernia of the present invention
1, physical data
Accept out-patient's totally 160 examples for medical treatment.
2, diagnostic criteria
Be mainly manifested in inguinal region, can see or touch hernia block.Stand, exert oneself, occur when coughing, flat sleeping time can disappear.When lump is given prominence to, disappear very soon immediately for upwards having pushed light resistance sense gently.Sometimes hear grunt simultaneously.In addition, when lump is given prominence to, patient has bearing down, with distending pain or involving property stomachache.There will be abdominal pain and distension simultaneously, constipation, resistance weaken, the symptom such as malnutrition, dyspepsia.
3, Therapeutic Method
Select above-mentioned medicament, take to patient, each serving with 1 dose, every day is early, middle and late respectively takes 1 time, within 5 days, is a course for the treatment of, takes 5 courses for the treatment of continuously.
4, efficacy assessment standard
Effective: hernia transference cure, body constitution recovers normal, observes half a year without recidivist;
Take a turn for the better: hernia symptom is clearly better, and body constitution is progressively recovered;
Invalid: not reach improvement standard person.
5, therapeutic outcome (seeing the following form)
In above-mentioned treatment, by Drug therapy hernia patient 160 example of the present invention, effective 155 examples of result, obvious effective rate is 96.875%, and take a turn for the better 3 examples, and improvement rate is 1.875%, and invalid 2 examples, total effective rate is 98.75%.
Claims (3)
1. treat a medicine for hernia, it is characterized in that: it is made up of the crude drug in following weight range:
Pericarpium Citri Reticulatae Viride 8-12 gram of Pericarpium Citri Reticulatae 8-12 gram of Thallus Laminariae (Thallus Eckloniae) 10-20 gram
Fructus Foeniculi 10-20 gram of Rhizoma Acori Calami 8-12 gram of Rhizoma Corydalis 8-12 gram
Fructus Toosendan 10-20 gram of Semen Citri Reticulatae 10-20 gram of Radix Aucklandiae 8-12 gram
Rhizoma Cyperi 8-12 gram of Cortex Cinnamomi 8-12 gram of Rhizoma Alpiniae Officinarum 8-12 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
Pericarpium Citri Reticulatae Viride 10 grams of Pericarpium Citri Reticulataes 10 grams of Thallus Laminariae (Thallus Eckloniae)s 15 grams
Fructus Foeniculi 15 grams of Rhizoma Acori Calami 10 grams of Rhizoma Corydalis 10 grams
Fructus Toosendan 15 grams of Semen Citri Reticulataes 15 grams of Radix Aucklandiae 10 grams
Rhizoma Cyperi 10 grams of Cortex Cinnamomis 10 grams of Rhizoma Alpiniae Officinarums 10 grams.
3. the preparation method of medicine according to claim 1 or 2, it comprises the following steps:
(1) get the raw materials ready
(1) Pericarpium Citri Reticulatae Viride: pick clean impurity, be soaked in water, pull out, run through, section, dries;
(2) Pericarpium Citri Reticulatae: get crude drug, the peel of removing impurity and blackening, wash quickly is clean, softens, shredding, dries or cold drying, sieve dedust bits;
(3) Thallus Laminariae (Thallus Eckloniae): pick decontamination, rinses with water, is cut into wide silk, dries;
(4) Fructus Foeniculi: get crude drug, removing impurity;
(5) Rhizoma Acori Calami: get crude drug, removing reed clothing, impurity, clean, run through, cut sheet, cold drying;
(6) Rhizoma Corydalis: pick decontamination, is soaked in water, and clean, solarization is dried in the air, and profit is even to inside and outside humidity, cuts into slices or smashes;
(7) Fructus Toosendan: pick decontamination, cleans, and dries, grating or cleave in two;
(8) Semen Citri Reticulatae: sieve dedust bits, pick clean impurity, clean, dry;
(9) Radix Aucklandiae: put by crude drug in whole in clear water and clean, pull out, moistening makes soft for 12-24 hours, section, dries;
(10) Rhizoma Cyperi: pick decontamination, is ground into particle, winnow with a dustpan fine, soft fur and smalls;
(11) Cortex Cinnamomi: pick clean impurity, scrape off rough bark, the used time smashes, or scrapes off rough bark, infiltrates a moment by warm water, and section, dries;
(12) Rhizoma Alpiniae Officinarum: pick clean impurity, washing, slightly soaks, pulls out, run through, and section, dries;
(2) prepare
(1) Pericarpium Citri Reticulatae Viride of described weight, Pericarpium Citri Reticulatae, Thallus Laminariae (Thallus Eckloniae), Fructus Foeniculi, Rhizoma Acori Calami, Rhizoma Corydalis, Fructus Toosendan, Semen Citri Reticulatae, the Radix Aucklandiae, Rhizoma Cyperi, Cortex Cinnamomi, Rhizoma Alpiniae Officinarum crude drug are added 6 times of water gagings and soak, soak after 60 minutes, intense fire decocts boiling 20 minutes, use slow fire boiling again 30 minutes, filter first time decoction liquor;
(2) add water the medicinal residues of filtration 4 times amount, and intense fire decocts boiling 10 minutes, then uses slow fire boiling 15 minutes, filters to obtain second time decoction liquor;
(3) by twice decoction liquor mixing and stirring, then use slow fire boiling 10 minutes, decoction liquor be divided into 3 doses to take.
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WO2019140623A1 (en) * | 2018-01-19 | 2019-07-25 | 昆山市申力毛纺有限公司 | Preparation methods and administration methods for drug for treating hernias |
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