CN103370012B - For the monitoring of postpartum hemorrhage - Google Patents
For the monitoring of postpartum hemorrhage Download PDFInfo
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- CN103370012B CN103370012B CN201180067459.8A CN201180067459A CN103370012B CN 103370012 B CN103370012 B CN 103370012B CN 201180067459 A CN201180067459 A CN 201180067459A CN 103370012 B CN103370012 B CN 103370012B
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- 208000018525 Postpartum Hemorrhage Diseases 0.000 title claims abstract description 32
- 238000012544 monitoring process Methods 0.000 title claims abstract description 16
- 230000002632 myometrial effect Effects 0.000 claims abstract description 53
- 208000032843 Hemorrhage Diseases 0.000 claims abstract description 35
- 238000010008 shearing Methods 0.000 claims abstract description 33
- 230000005855 radiation Effects 0.000 claims abstract description 16
- 238000002604 ultrasonography Methods 0.000 claims abstract description 6
- 238000000034 method Methods 0.000 claims description 23
- 210000004291 uterus Anatomy 0.000 claims description 15
- 238000004458 analytical method Methods 0.000 claims description 6
- 230000000638 stimulation Effects 0.000 claims description 5
- 230000003187 abdominal effect Effects 0.000 claims description 4
- 230000006870 function Effects 0.000 claims description 4
- 230000000007 visual effect Effects 0.000 claims description 4
- 238000001514 detection method Methods 0.000 abstract 1
- 206010021118 Hypotonia Diseases 0.000 description 6
- 230000008569 process Effects 0.000 description 6
- 206010027514 Metrorrhagia Diseases 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 210000004204 blood vessel Anatomy 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 230000003387 muscular Effects 0.000 description 3
- 208000036029 Uterine contractions during pregnancy Diseases 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 238000001228 spectrum Methods 0.000 description 2
- 208000002495 Uterine Neoplasms Diseases 0.000 description 1
- 206010047139 Vasoconstriction Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000035606 childbirth Effects 0.000 description 1
- 230000003930 cognitive ability Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 206010034754 petechiae Diseases 0.000 description 1
- 210000002826 placenta Anatomy 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000000644 propagated effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000003595 spectral effect Effects 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 206010046766 uterine cancer Diseases 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 230000025033 vasoconstriction Effects 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/48—Diagnostic techniques
- A61B8/485—Diagnostic techniques involving measuring strain or elastic properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
- A61B5/0004—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by the type of physiological signal transmitted
- A61B5/0011—Foetal or obstetric data
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/43—Detecting, measuring or recording for evaluating the reproductive systems
- A61B5/4306—Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
- A61B5/4343—Pregnancy and labour monitoring, e.g. for labour onset detection
- A61B5/4356—Assessing uterine contractions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/08—Clinical applications
- A61B8/0833—Clinical applications involving detecting or locating foreign bodies or organic structures
- A61B8/085—Clinical applications involving detecting or locating foreign bodies or organic structures for locating body or organic structures, e.g. tumours, calculi, blood vessels, nodules
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/42—Details of probe positioning or probe attachment to the patient
- A61B8/4209—Details of probe positioning or probe attachment to the patient by using holders, e.g. positioning frames
- A61B8/4227—Details of probe positioning or probe attachment to the patient by using holders, e.g. positioning frames characterised by straps, belts, cuffs or braces
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/08—Clinical applications
- A61B8/0866—Clinical applications involving foetal diagnosis; pre-natal or peri-natal diagnosis of the baby
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/56—Details of data transmission or power supply
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- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
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- Public Health (AREA)
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- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
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- Molecular Biology (AREA)
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- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Pregnancy & Childbirth (AREA)
- Physiology (AREA)
- Computer Networks & Wireless Communication (AREA)
- Vascular Medicine (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
- Surgical Instruments (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
Disclose a kind of for the equipment for postpartum hemorrhage monitoring experimenter.Described equipment comprises: ultrasonic transducer, and it for applying to focus on the ultrasonic energy at described experimenter's myometrial tissue region place to create acoustic radiation force, thus generates shearing wave in myometrial tissue.Radiate ultrasound energy in the body of described experimenter, and is received echo ultrasonic energy by the second ultrasonic transducer.By analyzing the signal representing the echo ultrasonic energy received, determine the shearing velocity of wave propagation in described myometrial tissue.Based on described shearing velocity of wave propagation, determine the value of the tension force of described myometrial tissue and conveyed to user.In addition, also disclose a kind of hemorrhage and estimate the equipment of its seriousness for detection and positioning.
Description
Technical field
The disclosure belongs to the field of monitoring human experimenter generally.Specifically, it belongs to the ultrasonic field of non-invasively monitoring human experimenter for postpartum hemorrhage of use.
Background technology
Worldwide, the much death relevant to childbirth is all caused by postpartum hemorrhage (PPH).Usually, divide the puerperium soon uterine contraction to close to normal size.When uterine contraction, the vasoconstriction in myometrial tissue and metrorrhagia stop.But, if there is residual Placenta Hominis in uterus, if or would not stop because other reasons myometrial tissue has lost tension force (tone)---a kind of situation being referred to as metratonia---is hemorrhage.If above-mentioned situation is not checked through, mother will experience and to lose blood seriously and this may be fatal.Usually, when baby due, the visual cognitive ability of care-giver is with it neonate, and if even if unmanned treatment mother of a bit of time and mother are just hemorrhage, result may be just fatal.
US Patent No.-2008/0139967A1 discloses a kind of electrode interface system, it is for providing the connection between at least one electrode and mother-foetal monitor, wherein, the electric muscular tissue activity captured by (one or more) electrode is converted to the data signal of uterine activity by described interface system, uses for described mother-foetal monitor.The invention of described electrode interface system preferably includes conversion method, and it is for being converted to the signal from (one or more) electrode and signal like the class signal produced by parturiometer (tocodynometer).This provide a kind of means for monitoring uterus tension force, atonia and potential hemorrhage alarm are provided.
Summary of the invention
Preferably, have a kind of equipment, it for non-invasively estimating the tension force of myometrial tissue in a more direct manner and monitoring experimenter within immediately puerperal a period of time, and provide alarm about PPH probability to user or care-giver.Also can be used for determining position hemorrhage in uterus and seriousness thereof it is further preferred that have such equipment.Further preferably, have a kind of equipment, it also provides decision support for care-giver processes PPH.
There is disclosed herein such equipment.A kind of equipment of the tension force for estimating myometrial tissue, wherein, described equipment comprises the first ultrasonic transducer, and it creates acoustic radiation force for the ultrasonic energy applying to focus on experimenter's myometrial tissue region place, thus generates shearing wave in myometrial tissue; Second ultrasonic transducer, its for by radiate ultrasound energy in subject, and receive echo ultrasonic energy; Analytic unit, for analyzing, it represents that the signal of the echo ultrasonic energy received is to determine the spread speed of described shearing wave in myometrial tissue; And processor unit, its value for the tension force based on described shearing velocity of wave propagation determination myometrial tissue is for further use.
The disclosed available advantage of equipment is, uses the value of the tension force of myometrial tissue, and experimenter can accept to prevent to lose blood seriously the Medicare of required necessity.Described equipment can also make it possible to occur to monitor experimenter for PPH in the position of next-door neighbour experimenter without the need to care-giver, and can provide giving more sustained attention experimenter.
In addition, also disclose a kind of system, it is for monitoring experimenter for metrorrhagia.For comprising for the described system of metrorrhagia monitoring experimenter: the first ultrasonic transducer, it for applying to focus on the ultrasonic energy at experimenter's myometrial tissue region place to create acoustic radiation force, thus generates shearing wave in described myometrial tissue; Second ultrasonic transducer, its for by radiate ultrasound energy in subject, and receive echo ultrasonic energy; Analytic unit, for analyzing, it represents that the signal of the echo ultrasonic energy received is to determine to shear velocity of wave propagation in myometrial tissue; Processor unit, it is for determining the value of the tension force of described myometrial tissue based on described shearing velocity of wave propagation; And user interface, its communicating information for the value by the tension force based on described myometrial tissue is to user.
The advantage that such system may have is, PPH can by care-giver's overall treatment.
Also preferably, have a kind of method, it is for detecting postpartum hemorrhage and warning care-giver about postpartum hemorrhage.Like this for estimating that the method for myometrial tissue tension force comprises the following steps: stimulation step, the ultrasonic energy applying to focus on experimenter's myometrial tissue region place to create acoustic radiation force, thus generates shearing wave in myometrial tissue; Irradiation step, by radiate ultrasound energy in subject, and receives echo ultrasonic energy; Analytical procedure, analyzes and represents that the signal of the echo ultrasonic energy received is to determine to shear velocity of wave propagation in described myometrial tissue; And treatment step, its value for the tension force based on described shearing velocity of wave propagation determination myometrial tissue is for further use.
The advantage that such method can have is, makes it possible to early discovery PPH, makes care-giver can process PPH and manages to accomplish that mother does not have life danger.
Accompanying drawing explanation
With reference to accompanying drawing, based on following examples or implementation, these and other aspect will be described by way of example in detail, wherein
Fig. 1 a is disclosed schematically showing for the equipment for postpartum hemorrhage monitoring experimenter;
Fig. 1 b is schematically showing of the embodiment of disclosed equipment;
Fig. 2 is schematically showing of the embodiment of disclosed equipment;
Fig. 3 is schematically showing of the embodiment of the disclosed system for monitoring experimenter for postpartum hemorrhage;
Fig. 4 is the disclosed graphic representation for the equipment for postpartum hemorrhage monitoring experimenter;
Fig. 5 monitors schematically showing of the method for experimenter for postpartum hemorrhage; And
Fig. 6 is schematically showing of another implementation of disclosed method,
Wherein, similar in different drawings Reference numeral represents similar part.
Detailed description of the invention
Equipment, system and method disclosed in describing in detail below with reference to accompanying drawing.
Fig. 1 is the schematic diagram of the embodiment of disclosed equipment.It comprises ultrasonic transducer 101, and this ultrasonic transducer 101 for applying to focus on the ultrasonic energy at experimenter's myometrial tissue region place to create acoustic radiation force, thus generates shearing wave in myometrial tissue.Ultrasonic transducer 101 is suitably driven by driving 105.Therefore described shearing wave produces the radiation through described myometrial tissue.Another ultrasonic transducer 103 by ultrasonic radiation in the abdominal part (midriff) of described experimenter.Ultrasonic and the analytic unit 107 that transducer 103 receives reflection is analyzed the signal of telecommunication that exported by transducer 103 and is measured described shearing velocity of wave propagation by known method, and estimates the tension force of myometrial tissue based on described spread speed.The result analyzed conveys to user by suitable user interface 111.
Ultrasonic transducer 101 is one group of individual transducer, and it is arranged and drives to make the radiation of being launched by the transducer of described array to focus on a pocket in myometrial tissue.Due to the acoustic radiation force created by described focus supersonic, shearing wave will occur in described focal zone, and described shearing wave is then radiated through described myometrial tissue.
But, once generate shearing wave, just can disconnect ultrasonic transducer 101 and shear wave propagation by transducer 103 radiate ultrasonic imaging pulse to follow the tracks of in the region around focal zone.Analytic unit 107 then analyzes the signal of the expression echo received by transducer 103 to estimate to shear wave propagation velocity.Because shearing wave is propagated faster than in softer material in harder material, thus obtain the estimation of the modulus of shearing of muscular tissue and the estimation of the therefore tension force of myometrial tissue by the shearing velocity of wave propagation measured.The modulus of shearing of muscular tissue can use perfect model to calculate.
Based on the modulus of shearing calculated, based on the appropriate threshold value for described modulus of shearing, uterine cancer cell can be classified as soft (that is, atonia), hard or hard (as there is enough tension force).Should be appreciated that, described classification may have larger rank, covers the four corner of tension force.Therefore, described classification also can obtain the different information conveying to user.
Once assess the tension force of myometrial tissue, just can by suitable mode by readout to user.If described tension force is assessed as and soft or evaluatedly there is atonia, then mean to there is hemorrhage probability.Equipment can then start to locate hemorrhage.
May it is contemplated that when tension force be sorted in scope centre or near middle time, that is, neither hard neither be soft, equipment can allow also again to measure tension force through predetermined time.If tension force remains unchanged or worsens, namely reduce, and if so equipment can continue monitoring hemorrhage existence then locate hemorrhage.
The feature of existence hemorrhage is in the blood vessel: the change of doppler velocity spectral profile and by the quantitative target analyzing such as drag index (RI) that spectrum waveform derives, pulsatility index (PI).Cause the front end diastole flow velocity improved in supply vessels in the minimizing of petechia and downstream vascular resistance thereof, cause the minimizing in Doppler's index.Also by the change of assessment in flow velocity is estimated, from Doppler signal spectrum, the measurement of the turbulent flow in affected blood vessel as hemorrhage seriousness is estimated.These Doppler parameters can be assessed from the diverse location in uterus.The remarkable minimizing of Doppler's index (RI, PI) or the increase of flow turbulence or both occur exists hemorrhage in instruction uterus.By combination from the information on the different qualities of the stream overview of Doppler measurement with by threshold application in each parameter, determine hemorrhage existence.Hemorrhage seriousness can pass to by Doppler's index quantitative in affected blood vessel and in calibration steps the independent amount of bleeding measured be associated and quantize.If the uterus of experimenter is soft and detects hemorrhage in uterus, then the alert trigger PPH that warns care-giver possible.
In addition, analytic unit 109 can be configured to provide about the suitable suggestion processing PPH, such as, by user interface 111 to care-giver.This embodiment is described with reference to Fig. 2.This suggestion can based on the atonic seriousness of myometrial tissue, hemorrhage position, hemorrhage seriousness and existing clinical guidelines.Various professional body periodically issues such clinical guidelines.Such as, " Prevention and Management of Postpartum Haemorrhage " has been issued by Canadian gynaecologist and obstetrician association (The Society of Obstetricians and Gynaecologists of Canada) (SOGC), see the document (on October 8th, 2010, can obtain from http://www.sogc.org/guidelines/public/88E-CPG-April2000.pdf) that the date is in April, 2000 No.88.The content of one or more such guide suitably can be stored in memorizer 213.Analytic unit 109, use suitable software, obtain the various information in memory of storage, and based on the result analyzed, determine or select one or more suitable action from clinical guidelines to process PPH and show selection to user in user interface 111.
For convenience of description, in the above description, the reception of the radiation of focusing pulse, the generation of ultrasonic radiation and echo is described to perform different functions by different transducers 101 and transducer 103, it is possible that by all function i ntegration mentioned to same transducer.This diagrammatically illustrates in Figure 1b.
Therefore disclosed equipment 200 can help to check metratonia, the existence of PPH and location and also have the process of assisting PPH.
With reference to figure 3, describe for monitoring system disclosed in experimenter for PPH, Fig. 3 is the diagram usually showing the system being 300.System 300 comprises disclosed equipment 100 or equipment 200 and remote unit 315.Remote unit 315 comprises user interface 311 ', and it may be copying of user interface elements 111.User interface 311 ' also can comprise extra characteristic.Such as, although user interface 111 may be aplhanumeric visual display, user interface 311 ' may have the characteristic of such as stroboscopic lamp or the audio frequency apparatus for the sound that gives the alarm.Remote unit 315 is communicated with equipment 100 or equipment 200 by wired or wireless mode, specifically communicates with processor unit 109.Described system can be arranged such that described remote unit is positioned at the place away from monitored experimenter, such as, in nurse station.When described unit 100 or unit 200 detect atonia hemorrhage or both time, user interface 111 and user interface 311 ' all show this information.If described system comprises unit 200, such as, unit 200 can provide for care-giver the suggestion how processing PPH, so also in the described suggestion of the upper display of described user interface 311 '.This make care-giver can defer to described suggestion by such as collect necessary material and, if necessary, assemble extra personnel to prepare.
Therefore, system 300 makes it possible to monitor metratonia in puerperal without the need to care-giver is close to experimenter, and in atonia or hemorrhage or also help when both occurring to provide treatment early.
Fig. 4 shows the possible implementation of disclosed equipment or system.Experimenter is shown as the execution thing 402 having worn belt shape, and it comprises necessary one or more transducers.Described transducer and described equipment are electrically connected.Described electronic equipment be arranged in show be 400 unit.Transducer in 402 and the combination of 400 are equipment described herein.Unit 400 can be interconnected with remote unit, and described remote unit is such as with reference to the remote unit 315 that figure 3 describes.This is the possible embodiment of disclosed equipment or equipment one, and can be design problem.
Describe disclosed method of monitoring experimenter for PPH with reference to figure 5, Fig. 5 is the graphic representation of method, and described method is designated generally as 500 in Figure 5.
In stimulation step 517, uterus is subject to the stimulation from experimenter's abdominal surface.This stimulation is that the mode by relying on focus supersonic to create shearing wave to experimenter uterus applying acoustic radiation force in myometrial tissue is carried out.Once focus supersonic generates shearing wave, just described focus supersonic can be stopped, and for being ultrasonicly radiated in subject in irradiation step 519 of measuring.In receiving step 521, receive echo ultrasonic energy and in analytical procedure 523, analyze the signal received and determine to shear velocity of wave propagation.The tension force of myometrial tissue is determined in treatment step 525.Determine atonic presence or absence based on described analysis, and in reception and registration step 525, pass on the information based on described decision to user.This reception and registration can be passed on equipment itself or information is passed at remote location by wired or wireless mode.
A kind of modification of said method is disclosed with reference to figure 6.This embodiment comprises the step outside with reference to the step described by figure 5.After analytical procedure 525, in further second analytical procedure 624, represent receive echo ultrasonic signal signal further analyzed determine following at least one item: hemorrhage, the hemorrhage seriousness in experimenter uterus and position hemorrhage in uterus.In second treatment step 626 of closelying follow treatment step 535, one or more based in position hemorrhage in atonic existence, atonic seriousness, hemorrhage existence, hemorrhage seriousness and uterus, select one or more messages meant to user from one group of message based on the clinical guidelines stored in a memory cell.In reception and registration step 527, except about except atonia presence or absence information, extra information, such as, in hemorrhage existence, hemorrhage seriousness, uterus, hemorrhage position is communicated to user, and also conveys to user about the suggestion of the process of PPH or suggestion.
Therefore, if PPH occur and when PPH occurs, such method can provide comprehensive information to support disposal or the process of PPH for care-giver.
Although describe in detail each embodiment and implementation in the accompanying drawings and the description, drawing and description should be understood to exemplary with nonrestrictive; The invention is not restricted to the disclosed embodiments.Practitioner can carry out changing and combining, and all changes are like this regarded as being within the scope of disclosed method.
Those skilled in the art when implementing the invention of advocating, is appreciated that and puts into practice other modification of the disclosed embodiments by research accompanying drawing, open and claim.In the claims, word " comprises " does not get rid of other elements or step, and indefinite article " " is not got rid of multiple.Single processor or transducer or other unit may realize the function of the some projects recorded in claim.This only has the fact not indicate can not advantageously to combine these measures to describe certain measures in mutually different dependent claims.Any Reference numeral in claim all should not be interpreted as the scope limiting claim.
Claims (9)
1. one kind for estimating the equipment (100) of the tension force of myometrial tissue, and described equipment comprises:
First ultrasonic transducer (101), it for applying the ultrasonic energy at the myometrial tissue region place focusing on experimenter to create acoustic radiation force, thus generates shearing wave in described myometrial tissue;
Second ultrasonic transducer (103), it is for receiving echo ultrasonic energy in radiate ultrasound energy to described subject;
Analytic unit (107), it is for analyzing the signal of the echo ultrasonic energy received by expression to determine to shear velocity of wave propagation described in described myometrial tissue; And
Processor unit (109), it is for the value of the modulus of shearing and the therefore described tension force of described myometrial tissue of determining described myometrial tissue based on the described spread speed of described shearing wave, for further use.
2. equipment (100) as claimed in claim 1, wherein, described analytic unit (107) for the described signal of analyzing the echo ultrasonic energy received by expression further with detect following at least one item: position hemorrhage described in existence hemorrhage in the described uterus of described experimenter, described hemorrhage seriousness and described uterus.
3. equipment as claimed in claim 1 or 2, wherein, described transducer is arranged in the structure (402) of belt shape, for described subject wears around abdominal part, and makes described transducer and abdominal part suitably contact with to ultrasonic described in described experimenter's internal radiation.
4. one kind for for postpartum hemorrhage monitoring experimenter system (300), described system comprises:
First ultrasonic transducer (101), it for applying the ultrasonic energy at the myometrial tissue region place focusing on experimenter to create acoustic radiation force, thus generates shearing wave in described myometrial tissue;
Second ultrasonic transducer (103), it is for receiving echo ultrasonic energy in radiate ultrasound energy to described subject;
Analytic unit (107), it is for analyzing the signal of the echo ultrasonic energy received by expression to determine to shear velocity of wave propagation described in described myometrial tissue;
Processor unit (109), it is for the value of the modulus of shearing and the therefore tension force of described myometrial tissue of determining described myometrial tissue based on the described spread speed of described shearing wave; And
User interface (111), it, for the described value of the described tension force based on described myometrial tissue, conveys a message to user.
5. system as claimed in claim 4, wherein, described user interface (111) comprise following at least one item: audible alarm generation unit, aplhanumeric visual display, video display unit and visual alarm indicating member.
6. system as claimed in claim 4, wherein, one or more for based in the described value of described tension force, hemorrhage existence, described hemorrhage seriousness and described hemorrhage position of described processor unit (109), select one or more message from based in one group of message of the clinical guidelines be stored in memory cell (213), convey to described user by described user interface (111).
7. system as claimed in claim 4, it can be operatively coupled to remote unit (315), described remote unit (315) comprises the second user interface apparatus (311 '), similar with described user interface (311) in fact, for copying the function of described user interface (311) at remote location.
8., for estimating a method for the tension force of myometrial tissue, said method comprising the steps of:
Stimulation step (517), applying focuses on the ultrasonic energy at experimenter's myometrial tissue region place to create acoustic radiation force, thus generates shearing wave in described myometrial tissue;
Irradiation step (519), radiate ultrasonic energy in described subject;
Receiving step (521), receives echo ultrasonic energy;
Analytical procedure (523), the signal analyzing the echo ultrasonic energy received by representing is determined to shear velocity of wave propagation described in described myometrial tissue; And
Treatment step (525), the described spread speed based on described shearing wave determines the modulus of shearing of described myometrial tissue and the value of the therefore described tension force of described myometrial tissue, for further use.
9. method as claimed in claim 8, also comprises and passes on step (527), passes on the information based on the described value of the described tension force of described myometrial tissue to user.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10194930.3 | 2010-12-14 | ||
| EP10194930 | 2010-12-14 | ||
| PCT/IB2011/055524 WO2012080909A1 (en) | 2010-12-14 | 2011-12-07 | Monitoring for postpartum hemorrhage |
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| Publication Number | Publication Date |
|---|---|
| CN103370012A CN103370012A (en) | 2013-10-23 |
| CN103370012B true CN103370012B (en) | 2015-10-21 |
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| CN201180067459.8A Active CN103370012B (en) | 2010-12-14 | 2011-12-07 | For the monitoring of postpartum hemorrhage |
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| CN (1) | CN103370012B (en) |
| BR (1) | BR112013014560A2 (en) |
| RU (1) | RU2604704C2 (en) |
| WO (1) | WO2012080909A1 (en) |
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| CN106175668B (en) * | 2016-06-27 | 2019-02-05 | 深圳中科和康科技有限公司 | A kind of monitor device simulated based on software and drive sound-light alarm |
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| CN101902971A (en) * | 2007-12-21 | 2010-12-01 | 皇家飞利浦电子股份有限公司 | Systems and methods for tracking and guiding high intensity focused ultrasound beams |
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| AU4044393A (en) * | 1992-03-26 | 1993-10-21 | Homecare Diagnostic Services | Fetal monitoring system |
| US5810731A (en) * | 1995-11-13 | 1998-09-22 | Artann Laboratories | Method and apparatus for elasticity imaging using remotely induced shear wave |
| US20040073094A1 (en) * | 2002-10-15 | 2004-04-15 | Baker Donald A. | Fetal monitoring systems with ambulatory patient units and telemetric links for improved uses |
| US7651511B2 (en) * | 2003-02-05 | 2010-01-26 | Vascular Control Systems, Inc. | Vascular clamp for caesarian section |
| US7297116B2 (en) * | 2003-04-21 | 2007-11-20 | Wisconsin Alumni Research Foundation | Method and apparatus for imaging the cervix and uterine wall |
| US20060089570A1 (en) * | 2004-10-25 | 2006-04-27 | Mansour Hebah N | Methods and devices for cervix measurement |
| US7828753B2 (en) | 2006-10-18 | 2010-11-09 | Convergent Engineering, Inc. | Electrode interface system |
| US8727986B2 (en) * | 2009-02-27 | 2014-05-20 | Wisconsin Alumni Research Foundation | Method and apparatus for assessing risk of preterm delivery |
| RU98112U1 (en) * | 2010-04-19 | 2010-10-10 | Афанасий Афанасьевич Вержак | DEVICE FOR STOPPING OF POST-PERMANENT UTERINE BLEEDING |
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2011
- 2011-12-07 CN CN201180067459.8A patent/CN103370012B/en active Active
- 2011-12-07 WO PCT/IB2011/055524 patent/WO2012080909A1/en active Application Filing
- 2011-12-07 RU RU2013132468/14A patent/RU2604704C2/en not_active IP Right Cessation
- 2011-12-07 BR BR112013014560A patent/BR112013014560A2/en not_active Application Discontinuation
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5993389A (en) * | 1995-05-22 | 1999-11-30 | Ths International, Inc. | Devices for providing acoustic hemostasis |
| CN101902971A (en) * | 2007-12-21 | 2010-12-01 | 皇家飞利浦电子股份有限公司 | Systems and methods for tracking and guiding high intensity focused ultrasound beams |
Also Published As
| Publication number | Publication date |
|---|---|
| BR112013014560A2 (en) | 2016-09-20 |
| CN103370012A (en) | 2013-10-23 |
| RU2013132468A (en) | 2015-01-20 |
| RU2604704C2 (en) | 2016-12-10 |
| WO2012080909A1 (en) | 2012-06-21 |
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