CN103251851B

CN103251851B - Internal and external traditional Chinese medicine formulation for treating rheumatic and rheumatoid diseases

Info

Publication number: CN103251851B
Application number: CN201310201285.0A
Authority: CN
Inventors: 徐春娟; 郑爱惜; 田军政
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-05-27
Filing date: 2013-05-27
Publication date: 2014-11-19
Anticipated expiration: 2033-05-27
Also published as: CN103251851A

Abstract

The invention discloses a traditional Chinese medicine formulation for treating rheumatic and rheumatoid diseases, and the traditional Chinese medicine formulation is prepared from the following traditional Chinese medicine raw materials in parts by weight: 6-15 parts of pawpaw, 15-30 parts of coix seeds, 3-9 parts of zaocys dhumnade, 2-6 parts of cinnamomum cassia, 9-15 parts of semen sojae preparatum, 6-13 parts of radix achyranthis bidentatae, 9-13 parts of sapanwood, 3-10 parts of red flowers, 9-15 parts of eucommia bark, 10-15 parts of mulberry fruits, 10-15 parts of dipsacus roots, 10-30 parts of concha ostreae and 15-30 parts of dioscorea nipponica. The traditional Chinese medicine formulation disclosed by the invention has the effects of eliminating chill and dampness and relieving pain, nourishing and activating blood and relaxing muscles, warmly invigorating liver and kidney, clearing and activating channels and collaterals, strengthening body resistance and eliminating evil, enhancing immunity and achieving the twice curative effect with half effort.

Description

A kind of external application treatment rheumatism for oral administration and rheumatoid Chinese medicine preparation

Technical field

The present invention relates to a kind of pharmaceutical preparation taking animals and plants as raw material, particularly one and be used for the treatment of rheumatism, rheumatoid Chinese medicine preparation.

Background technology

Rheumatism is one group of disease of the musculoskeletal system taking Drug therapy as master, and it comprises: the disease of the joint that Diffuse Connective Tissue Disease and the various cause of disease cause and periarticular soft tissues, muscle, tendon, ligament etc., and taking the large arthralgia of extremity as main.

Rheumatoid arthritis is one, and to involve joint be around the main struvite autoimmune disease of multisystem, its distinctive symptom is symmetry, multiple joints chronic inflammation pathological changes around, clinical manifestation is the arthralgia of getting involved, swelling, function reduction, and pathological changes becomes to continue, episode process repeatedly.Its pathology is chronic synovitis, invades and cartilage and the bone of lower floor, causes destruction of joint.

Clinical manifestation: 80% was fallen ill in 35-50 year, and women is 3 times of male.Feature is with slowly and concealment mode onset.Joint performance has 3 features: 1. morning deadlock: night and morning ankylosis as gluing.2. arthralgia: the most common is wrist, metacarpal bone joint, is secondly toe, knee joint, ankle, elbow, shoulder joint.Having a cold swells and ache increases the weight of.3. joint deformity: be more common in patients with terminal.The flexion joint deformities such as finger, wrist, foot, toe.Periarticular amyotrophy, spasm make deformity even more serious.

The traditional Chinese medical science thinks that rheumatism, rheumatoid disease are all under the condition because of the many factors such as human righteousness's deficiency, disharmony of nutrient QI with defensive QI, deficiency of both QI and blood, internal organs weakness or a certain factor, wind-cold damp pathogen is taken advantage of a weak point, invade collaterals of human, joint, muscle, skeleton etc. and locate, cause above-mentioned clinical manifestation.Primary disease also climate cold affects and outbreak repeatedly, and obstinate disease person has caused QI and blood heavy losses, causes the stiff deformity of extremities joint, limitation of activity, and hurt like hell, even disability, brings great misery to patient.

Not yet clear and definite about rheumatism and rheumatoid etiology and pathogenesis, think at present relevant with autoimmune.It is main that most of medical institutions take control pain, takes a large amount of ibuprofens, diclofenac, indometacin etc., and some Patients with Acutes are taken hormones and controlled, and mitigation symptoms finally fails to break away from the misery that this disease is brought.

Summary of the invention

The object of the present invention is to provide a kind of external application for oral administration to be used for the treatment of rheumatism, rheumatoid Chinese medicine preparation.

A kind of external application treatment rheumatism for oral administration and rheumatoid Chinese medicine preparation, its raw material of Chinese medicine by following weight portion is made: Fructus Chaenomelis 6-15, Semen Coicis 15-30, black-snake 3-9, Cortex Cinnamomi 2-6, tasteless preserved soybean 9-15, Radix Achyranthis Bidentatae 6-13, Lignum Sappan 9-13, Flos Carthami 3-10, Cortex Eucommiae 9-15, Fructus Mori 10-15, Radix Dipsaci 10-15, Concha Ostreae 10-30, Dioscorea nipponica Mak. Ningpo Yam Rhizome 15-30.

The preferential one of recommending of the present invention external application treatment rheumatism for oral administration and rheumatoid Chinese medicine preparation, its raw material of Chinese medicine by following weight portion is made: Fructus Chaenomelis 15, Semen Coicis 19, black-snake 9, Cortex Cinnamomi 6, tasteless preserved soybean 15, Radix Achyranthis Bidentatae 13, Lignum Sappan 13, Flos Carthami 6, the Cortex Eucommiae 13, Fructus Mori 10, Radix Dipsaci 13, Concha Ostreae 15, Dioscorea nipponica Mak. Ningpo Yam Rhizome 19.

Component effect of the present invention is as follows:

Fructus Chaenomelis-damp eliminating relaxing muscles and tendons, the stomach function regulating of being amusing;

Semen Coicis-inducing diuresis to remove edema, damp eliminating eliminating impediment, evacuation of pus disappear bitterly, invigorating the spleen to arrest diarrhea;

Black-snake-dispelling wind and removing obstruction in the collateral, determine convulsion pain relieving;

Cortex Cinnamomi-warming middle-JIAO YANG invigorating, dispersing cold for relieving pain;

Strongly fragrant relieving restlessness is induced sweat, is declared in tasteless preserved soybean-evacuation;

Radix Achyranthis Bidentatae-promoting blood circulation to restore menstrual flow, relaxing muscles and tendons profit numbness, conducting blood to flow downwards, inducing diuresis for treating stranguria syndrome;

Lignum Sappan-blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain;

Flos Carthami-promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing;

The Cortex Eucommiae-invigorating the liver and kidney, bone and muscle strengthening, blood pressure lowering;

Fructus Mori-nourishing YIN and supplementing blood;

Radix Dipsaci-the liver and the kidney tonifying, activating collaterals to relieve pain, reuniting the fractured tendons and bones, treatment injured, Gu through only collapsing;

Concha Ostreae-tranquillizing and allaying excitement, tonifying YIN YANG hyperactivity suppressing, restrain astringent or styptic treatment for spontaneous sweating, hard masses softening and resolving;

Dioscorea nipponica Mak. Ningpo Yam Rhizome-channels sootheing and network vessel quickening, promoting blood circulation and stopping pain.

The present invention has cold-dispelling removing damp and stopping pain, nourshing blood and promoting blood circulation relaxing muscles and tendons, temperature compensation Liver and kidney, bone and muscle strengthening, dredge the meridian passage, strengthening vital QI to eliminate pathogenic factors, enhancing human body immunity power, repair destroyed osteoarthrosis and periarticular tissue, thereby reach the curative effect of getting twice the result with half the effort by external application for oral administration.

The present invention, at treatment rheumatoid arthritis, rheumatic arthritis and relevant joint disease, comprises that scapulohumeral periarthritis, sciatica, ankylosing spondylitis, prolapse of lumbar intervertebral disc, lumbar muscle strain, hyperosteogeny, cervical spondylosis, lumbago, skelalgia of rheumatism etc. all have good curative effect.

Detailed description of the invention

Formula 1: Fructus Chaenomelis 6, Semen Coicis 30, black-snake 3, Cortex Cinnamomi 6, tasteless preserved soybean 9, Radix Achyranthis Bidentatae 13, Lignum Sappan 9, Flos Carthami 10, the Cortex Eucommiae 9, Fructus Mori 15, Radix Dipsaci 10, Concha Ostreae 30, Dioscorea nipponica Mak. Ningpo Yam Rhizome 15.

Formula 2: Fructus Chaenomelis 15, Semen Coicis 15, black-snake 9, Cortex Cinnamomi 2, tasteless preserved soybean 15, Radix Achyranthis Bidentatae 6, Lignum Sappan 13, Flos Carthami 3, the Cortex Eucommiae 15, Fructus Mori 10, Radix Dipsaci 15, Concha Ostreae 10, Dioscorea nipponica Mak. Ningpo Yam Rhizome 30.

Formula 3: Fructus Chaenomelis 15, Semen Coicis 19, black-snake 9, Cortex Cinnamomi 6, tasteless preserved soybean 15, Radix Achyranthis Bidentatae 13, Lignum Sappan 13, Flos Carthami 6, the Cortex Eucommiae 13, Fructus Mori 10, Radix Dipsaci 13, Concha Ostreae 15, Dioscorea nipponica Mak. Ningpo Yam Rhizome 19.

Said components is made oral preparations and externally applied formulation, and externally applied formulation adopts yellow wine to mix and stir medicated powder and make

Usage and consumption: oral, 3 times/every day, 5-9g/ was each; External application, medicated powder is mixed use (external application affected part) with yellow wine

The course for the treatment of: 45 days per courses for the treatment of, patient with slight symptoms need use for 1 course for the treatment of, patient with severe symptoms need use the 2-3 course for the treatment of.

Attention:

1, serious hypertension and cardiac are cautious use of or follow the doctor's advice;

2, women breast-feeding their children and anemia of pregnant woman's forbidding.

The some cases of inventor's in January, 2011-2013 year treatment in January is summarized as follows:

One, source of data: in January, 2011-2013 the present invention in 3 years year January adopts the patient of prescription treatment rheumatoid arthritis, rheumatic arthritis and relevant joint disease.

Two, diagnostic criteria: with reference to practical internal medicine diagnostic criteria, according to patient's history of present illness, there is above clinical symptoms and sign, and in conjunction with chemical examination anti-" O ", rheumatoid molecule, the inspections such as X-ray film or CT sheet are made a definite diagnosis.

Three, clinical effectiveness criterion:

Criterion of cure: the symptoms such as patient's diseased region swells and ache, numbness disappear completely, and limb activity functional rehabilitation is normal.Relevant chemical examination, X-ray film, CT sheet normal.

Improvement standard: the symptoms such as patient's diseased region swells and ache, numbness obviously alleviate, flexible before limb function activity.Relevant chemical examination, X-ray film, CT sheet approach normal.

Four, Therapeutic Method:

By the rheumatoid arthritis of accepting for medical treatment, rheumatic arthritis and relevant joint disease, comprise scapulohumeral periarthritis, sciatica, ankylosing spondylitis, prolapse of lumbar intervertebral disc, lumbar muscle strain, hyperosteogeny, cervical spondylosis, lumbago, skelalgia of rheumatism patient, according to symptom weight, be divided into patient with severe symptoms and the large class of patient with slight symptoms two.

Patient with slight symptoms is each serving using 5-6 gram of former medicine; Patient with severe symptoms is each serving using the former medicine of 8-9g, every day 3 times.The for oral administration water decoction that adopts, all patients equal every day three times mixes and stirs with yellow wine the affected part of applying ointment or plaster after medicated powder.

The course for the treatment of: 45 days per courses for the treatment of, patient with slight symptoms need take for 1 course for the treatment of, patient with severe symptoms need take the 2-3 course for the treatment of.

Five, result statistics: part patient's curative effect for the treatment of is as follows:

Name of disease number of cases is cured the invalid cure rate effective percentage that takes a turn for the better

Rheumatoid arthritis 398 267 129 2 67.1% 99.5%

Rheumatic arthritis 216 174 39 2 80.1% 92.6%

Cervical spondylosis 165 131 30 1 79.4% 99.4%

Prolapse of lumbar intervertebral disc 191 106 62 23 55.5% 87.9%

Lumbar muscle strain 245 216 21 8 88.1% 96.7%

Scapulohumeral periarthritis 163 131 29 3 80.4% 98.1%

Six, conclusion

The present invention's active Radix Achyranthis Bidentatae that stimulates the menstrual flow, invigorates blood circulation by dispeling the wind, in addition the Cortex Eucommiae of strong muscles and bones, and relax through medicines such as the Dioscorea nipponica Mak. Ningpo Yam Rhizomes of dredging collateral, for rheumatoid arthritis, rheumatic arthritis and relevant joint disease, comprise that scapulohumeral periarthritis, sciatica, ankylosing spondylitis, prolapse of lumbar intervertebral disc, lumbar muscle strain, hyperosteogeny, cervical spondylosis are all effective in cure.

Claims

1. treatment rheumatism and a rheumatoid Chinese medicine preparation, is characterized in that being made up of the raw material of Chinese medicine of following weight portion: Fructus Chaenomelis 6-15, Semen Coicis 15-30, Zaocys 3-9, Cortex Cinnamomi 2-6, Semen Sojae Preparatum 9-15, Radix Achyranthis Bidentatae 6-13, Lignum Sappan 9-13, Flos Carthami 3-10, Cortex Eucommiae 9-15, Fructus Mori 10-15, Radix Dipsaci 10-15, Concha Ostreae 10-30, Dioscorea nipponica Mak. Ningpo Yam Rhizome 15-30; And described preparation comprises oral preparations and externally applied formulation, externally applied formulation adopts yellow wine to mix and stir medicated powder and makes.

2. one according to claim 1 is treated rheumatism and rheumatoid Chinese medicine preparation, it is characterized in that being made up of the raw material of Chinese medicine of following weight portion: Fructus Chaenomelis 15, Semen Coicis 19, Zaocys 9, Cortex Cinnamomi 6, Semen Sojae Preparatum 15, Radix Achyranthis Bidentatae 13, Lignum Sappan 13, Flos Carthami 6, the Cortex Eucommiae 13, Fructus Mori 10, Radix Dipsaci 13, Concha Ostreae 15, Dioscorea nipponica Mak. Ningpo Yam Rhizome 19.