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CN103230902B - Enzyme-labeling washing plate mechanism - Google Patents

Enzyme-labeling washing plate mechanism Download PDF

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Publication number
CN103230902B
CN103230902B CN201310098559.8A CN201310098559A CN103230902B CN 103230902 B CN103230902 B CN 103230902B CN 201310098559 A CN201310098559 A CN 201310098559A CN 103230902 B CN103230902 B CN 103230902B
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washing
enzyme
plate
driving member
eccentric wheel
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CN103230902A (en
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张利凡
郭宣城
甘宜梧
张昔坤
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Biobase Biodustry Shandong Co Ltd
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Biobase Biodustry Shandong Co Ltd
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Abstract

The invention relates to an enzyme-labeling washing plate mechanism. In a conventional enzyme-labeling washing plate mechanism, the vertical movement of a cleaning head is achieved through a screw lift mechanism, but requirements for machining accuracy are higher, the cost is high, and the volume is larger, so that the enzyme-labeling washing plate mechanism is enabled to be heavy and cumbersome. Therefore, the enzyme-labeling washing plate mechanism comprises a workbench, a fixing bracket, as well as a washing plate mechanism and a reading mechanism which are mounted on the fixing bracket, the washing plate mechanism comprises a cleaning head module and a washing head transmission module, the washing head transmission module comprises an eccentric wheel transmission mechanism for controlling a liquid absorbing head to move up and down, and a synchronous belt transmission mechanism for controlling the horizontal movement of the washing plate mechanism; and an enzyme-labeling plate placement region with an incubation function is arranged on the workbench, and at least one enzyme-labeling plate is placed in the enzyme-labeling plate placement region. The enzyme-labeling washing plate mechanism provided by the invention is scientific in design, is convenient and quick to operate, and can achieve the integration of plate washing and reading; and the volume is reduced, the kinematic accuracy is enhanced, the cost is lowered, the working efficiency is improved at the same time, and the plate washing is clean and thorough.

Description

Enzyme-linked washing-board mechanism
Technical field
The present invention relates to a kind of clinical treatment equipment, particularly a kind of Enzyme-linked washing-board mechanism for automatic enzyme immune work station.
Background technology
ELIAS microplate washer is a kind of equipment for the cleaning of enzyme inspection-free survey 96 hole ELISA Plate, is a requisite equipment in the inspection-free survey of enzyme.At present, ELIAS microplate washer at home situation of all-level hospitals be used widely.ELIAS microplate washer is easy and simple to handle, reliability is high, adapt to plurality of specifications ELISA Plate, overcomes the manual shortcoming of washing plate of intersecting.
Existing ELIAS microplate washer, if the patent No. is for washing trigger disclosed in CN96207598.1, comprising can the workbench of horizontal movement and the cleaning head that can move both vertically.Cleaning head comprises row's aspirating needle and row's injection needle.The horizontal movement of workbench is realized by Timing Belt and guide post, and moving both vertically of cleaning head is realized by screw thread elevating mechanism.But screw thread elevating mechanism requirement on machining accuracy is higher, and cost is higher, and volume is comparatively large, makes Enzyme-linked washing-board mechanism too cumbersome.In addition, the cleaning head of traditional ELIAS microplate washer is unfixed in the vertical direction, aspirating needle only leans on gravity pressure bottom ELISA Plate micropore cup, be difficult to the level ensureing cleaning needle like this, and can not fit tightly bottom aspirating needle and ELISA Plate micropore cup, cause raffinate amount larger, wash plate not thorough.
Summary of the invention
The technical problem to be solved in the present invention is the above-mentioned defect how overcoming prior art, a kind of Enzyme-linked washing-board mechanism is provided, this Enzyme-linked washing-board mechanism can realize the integration of washing plate and reading, convenient to operation, and reduce volume, improve kinematic accuracy, simplify the internal structure of an organization, reduce costs, increase work efficiency simultaneously, wash plate totally thorough.
For solving the problems of the technologies described above, this Enzyme-linked washing-board mechanism, comprise workbench, fixed mount and be arranged on and fixed mount washes trigger structure and reading mechanism, wash trigger structure and comprise cleaning head module and hair washing transmission module, hair washing transmission module comprises the eccentric wheel drive mechanism that control fluid suction head moves up and down and the synchronous belt drive mechanism controlling to wash the horizontal movement of trigger structure; Workbench is provided with the ELISA Plate put area with incubation function, and ELISA Plate put area can place at least one ELISA Plate.
Design like this, by adopting eccentric wheel drive mechanism convenient to operation, reducing costs, and reducing volume; Additionally by eccentric wheel drive mechanism and cleaning head module reasonable coordination, cleaning head is fixed in the vertical direction, aspirating needle can fit tightly bottom micropore cup, maintenance level, decreases residual waste liquid amount, improves operating efficiency, make to wash plate more thorough, result of the test is more accurate.
As optimization, eccentric wheel drive mechanism comprises motor, code-disc, eccentric wheel, transmission device and driven pulley, motor is arranged on motor plate side, and code-disc is fixedly connected with eccentric wheel and is arranged on motor plate opposite side, and the motor shaft of motor is by jackscrew fastening through eccentric centre bore; Eccentric eccentric orfice is provided with driven pulley, and four angles of motor plate are respectively equipped with a driven pulley, and driven pulley is fixed on motor plate by axle; Transmission device is the driving member that can slide up and down along with eccentric wheel; In the middle of driving member and both sides are provided with gathering sill, and the gathering sill in the middle of this driving member is through the driven pulley on eccentric wheel, and the gathering sill of these driving member both sides coordinates with the driven pulley on both sides respectively; Driving member is provided with drive link, and drive link one end is installed on driving member, and the other end inserts in the hole in the middle of hair washing driving member through cover plate; Motor plate is provided with the photoelectric sensor by electric control system controls electric machine rotation, and the gap in the middle of this photoelectric sensor is through code-disc.Design like this, structure is simple, cost is lower, small volume, convenient to operation.
As optimization, the guard shield that cleaning head module comprises fluid suction head, filling head and both linked together; The upper end of fluid suction head has inverted T shape gathering sill, is inserted with I shape hair washing driving member in inverted T shape gathering sill; I shape hair washing driving member lower end is inserted in inverted T shape gathering sill, and upper end is connected with fluid suction head by the spring that two are in compressive state all the time; Fluid suction head is arranged on guard shield inside, and fluid suction head is provided with the cover plate that this fluid suction head can only be moved up and down; Filling head is arranged on guard shield by screw; Fluid suction head is provided with aspirating needle, and filling head is provided with injection needle, keeps fixing distance between aspirating needle and injection needle; Cleaning head module is fixed on motor plate by two support columns, and motor plate is arranged on fixed mount by screw.Design like this, aspirating needle can fit tightly bottom micropore cup, keeps level, decreases residual waste liquid amount, improve operating efficiency, and make to wash plate more thorough, result of the test is more accurate.
During work, under the drive of motor, eccentric wheel is along with rotation, and the driven pulley in the middle of driving member in gathering sill and then rotates, and under the effect of bias, driving member pumps; Meanwhile, under the effect of guide post, hair washing driving member also can along with pumping.When imbibition, hair washing driving member applies pressure by spring to fluid suction head, aspirating needle is made to touch the bottom of ELISA Plate micropore cup, now, in the middle of eccentric wheel drives, driven pulley continues to rotate to bottom, hair washing driving member continues to decline under the effect of drive link, Compress Spring, and the aspirating needle effect of being under pressure will be attached to the bottom of micropore cup tightly; Imbibition is carried out under being operated in control circui automatically, and after completing, eccentric wheel continues to rotate, and middle driven pulley starts to rise, and fluid suction head rises along with driving member, departs from micropore cup.
As optimization, synchronous belt drive mechanism comprises the guide rail be fixed under workbench, the reading mechanism that is fixed together with Timing Belt and the roller that can roll along guide rail; Reading mechanism is arranged on fixed mount by screw, reading mechanism is built with the electro-optical system of enzyme mark reading, bottom reading mechanism, four angles are separately installed with and can step up guide rail and along the roller of horizontal movement outside guide rail, the axle of roller is arranged on reading mechanism by screw; Guide rail two ends to be arranged on bottom workbench and the holder be provided with for supporting this guide rail; The Timing Belt that degree of tightness is adjustable is fixed on the bottom of reading mechanism, and two ends are enclosed within synchronous pulley and Timing Belt driven pulley respectively; Fastening with jackscrew on the axle that synchronous pulley is arranged on stepper motor; Guide rail is provided with the catch for photoelectricity location, photoelectric sensor is positioned by the gap on induction catch.
During work, stepper motor controls the horizontal movement of reading mechanism by Timing Belt, thus controls the horizontal movement of fixed mount and whole cleaning head module.During fluid injection, injection needle moves to directly over micropore cup, electric control system controls fluid injection; Then, directly over aspirating needle horizontal movement to the micropore cup filling liquid, electric control system controls imbibition, after imbibition completes, aspirating needle lifts, and continues horizontal movement to the next position.
Enzyme-linked washing-board mechanism of the present invention, structure is simple, design science, convenient to operation, can realize the integration of washing plate and reading, and reduce volume, improve kinematic accuracy, simplify the internal structure of an organization, reduce costs, increase work efficiency simultaneously, wash plate totally thorough; There is good actual application value and promotional value.
Accompanying drawing explanation
Below in conjunction with accompanying drawing, this Enzyme-linked washing-board mechanism is described further:
Fig. 1 is the assembly structure schematic diagram of this Enzyme-linked washing-board mechanism;
Fig. 2 is the cleaning head module assembly structure schematic diagram of this Enzyme-linked washing-board mechanism;
Fig. 3 is the fluid suction head assembly structure schematic diagram of this Enzyme-linked washing-board mechanism;
Fig. 4 is cleaning head module and the eccentric wheel transmission module assembly structure schematic diagram of this Enzyme-linked washing-board mechanism;
Fig. 5 is the main TV structure schematic diagram of the eccentric wheel drive mechanism of this Enzyme-linked washing-board mechanism;
Fig. 6 is the left TV structure schematic diagram of the eccentric wheel drive mechanism of this Enzyme-linked washing-board mechanism;
Fig. 7 is the backsight structural representation of the eccentric wheel drive mechanism of this Enzyme-linked washing-board mechanism;
Fig. 8 is the structural representation of this Enzyme-linked washing-board mechanism.
In figure: 1 is workbench, 2 is ELISA Plate, 3 is fixed mount, 4 is cleaning head module, 5 is eccentric wheel drive mechanism, 6 is synchronous belt drive mechanism, 7 is reading mechanism, 8 is fluid suction head, 9 is filling head, 10 is guard shield, 11 is hair washing driving member, 12 is spring, 13 is cover plate, 14 is support column, 15 is motor plate, 16 is motor, 17 is code-disc, 18 is eccentric wheel, 19 is driving member, 20 is photoelectric sensor, 21 is driven pulley, 22 is axle, 23 is roller, 24 is guide rail, 25 is stepper motor, 26 is synchronous pulley, 27 is catch, 28 is Timing Belt, 29 is Timing Belt driven pulley.
Detailed description of the invention
For making object of the present invention, technical scheme and advantage clearly understand, to develop simultaneously embodiment referring to accompanying drawing, the present invention is described in more detail.
As shown in Fig. 1 to 8, this Enzyme-linked washing-board mechanism, comprise workbench 1, fixed mount 3 and be arranged on and fixed mount 3 washes trigger structure and reading mechanism 7, wash trigger structure and comprise cleaning head module 4 and hair washing transmission module, it is characterized in that: hair washing transmission module comprises the eccentric wheel drive mechanism 5 that control fluid suction head 8 moves up and down and the synchronous belt drive mechanism 6 controlling to wash the horizontal movement of trigger structure; Workbench 1 is provided with the ELISA Plate put area with incubation function, and ELISA Plate put area can place at least one ELISA Plate 2.
Eccentric wheel drive mechanism comprises motor 16, code-disc 17, eccentric wheel 18, transmission device and driven pulley 21, motor 16 is arranged on motor plate 15 side, code-disc 17 is fixedly connected with eccentric wheel 18 and is arranged on motor plate 15 opposite side, and the motor shaft of motor 16 is fastening by jackscrew through the centre bore of eccentric wheel 18; The eccentric orfice of eccentric wheel 18 is provided with driven pulley 21, four angles of motor plate 15 are respectively equipped with a driven pulley 21, and driven pulley 21 is fixed on motor plate 15 by axle 22; Transmission device is the driving member 19 that can slide up and down along with eccentric wheel 18; In the middle of driving member 19 and both sides are provided with gathering sill, and the gathering sill in the middle of this driving member 19 is through the driven pulley 21 on eccentric wheel 18, and the gathering sill of these driving member 19 both sides coordinates with the driven pulley 21 on both sides respectively; Driving member 19 is provided with drive link, and drive link one end is installed on driving member 19, and the other end inserts in the hole in the middle of hair washing driving member 11 through cover plate 13; Motor plate 15 is provided with the photoelectric sensor 20 rotated by electric control system controls motor 16, and the gap in the middle of this photoelectric sensor 20 is through code-disc 17.
The guard shield 10 that cleaning head module 4 comprises fluid suction head 8, filling head 9 and both linked together; The upper end of fluid suction head 8 has inverted T shape gathering sill, is inserted with I shape hair washing driving member 11 in inverted T shape gathering sill; I shape hair washing driving member 11 lower end is inserted in inverted T shape gathering sill, and upper end is connected with fluid suction head 8 by the spring 12 that two are in compressive state all the time; It is inner that fluid suction head 8 is arranged on guard shield 10, and fluid suction head 8 is provided with the cover plate 13 that this fluid suction head 8 can only be moved up and down; Filling head 9 is arranged on guard shield 10 by screw; Fluid suction head 8 is provided with aspirating needle, and filling head 9 is provided with injection needle, keeps fixing distance between aspirating needle and injection needle; Cleaning head module 4 is fixed on motor plate 15 by two support columns 14, and motor plate 15 is arranged on fixed mount 3 by screw.
The reading mechanism 7 that synchronous belt drive mechanism 6 comprises the guide rail 24 be fixed under workbench 1, be fixed together with Timing Belt 28 and the roller 23 that can roll along guide rail 24; Reading mechanism 7 is arranged on fixed mount 3 by screw, reading mechanism 7 is built with the electro-optical system of enzyme mark reading, bottom reading mechanism 7, four angles are separately installed with and can step up guide rail 24 and along the roller 23 of horizontal movement outside guide rail 24, the axle of roller 23 is arranged on reading mechanism 7 by screw; Guide rail 24 two ends to be arranged on bottom workbench 1 and the holder be provided with for supporting this guide rail 24; The Timing Belt 28 that degree of tightness is adjustable is fixed on the bottom of reading mechanism 7, and two ends are enclosed within synchronous pulley 26 and Timing Belt driven pulley 29 respectively; Fastening with jackscrew on the axle that synchronous pulley 26 is arranged on stepper motor 25; Guide rail 24 is provided with the catch 27 for photoelectricity location, photoelectric sensor 20 is positioned by the gap on induction catch 27.
During work, under the drive of motor 16, eccentric wheel 18 is along with rotation, and the driven pulley 21 in the middle gathering sill of driving member 19 and then rotates, and under the effect of bias, driving member 19 pumps; Meanwhile, under the effect of guide post, hair washing driving member 11 also can along with pumping.When imbibition, hair washing driving member 11 applies pressure by spring 12 pairs of fluid suction head, aspirating needle is made to touch the bottom of ELISA Plate 2 micropore cup, now, eccentric wheel 18 drives middle driven pulley 21 to continue to rotate to bottom, hair washing driving member 11 continues to decline under the effect of drive link, Compress Spring 12, and the aspirating needle effect of being under pressure will be attached to the bottom of micropore cup tightly; Imbibition is carried out under being operated in control circui automatically, and after completing, eccentric wheel 18 continues to rotate, and middle driven pulley 21 starts to rise, and fluid suction head rises along with driving member 19, departs from micropore cup.Stepper motor 25 controls the horizontal movement of reading mechanism 7 by Timing Belt 28, thus controls the horizontal movement of fixed mount 3 and whole cleaning head module 4; During fluid injection, injection needle moves to directly over micropore cup, electric control system controls fluid injection; Then, directly over aspirating needle horizontal movement to the micropore cup filling liquid, electric control system controls imbibition, after imbibition completes, aspirating needle lifts, and continues horizontal movement to the next position.
Above-mentioned detailed description of the invention is only concrete case of the present invention; scope of patent protection of the present invention includes but not limited to product form and the style of above-mentioned detailed description of the invention; any meet claims of the present invention Enzyme-linked washing-board mechanism and any person of an ordinary skill in the technical field to its suitable change done or modification, all should fall into scope of patent protection of the present invention.

Claims (9)

1. an Enzyme-linked washing-board mechanism, comprise workbench (1), fixed mount (3) and be arranged on and described fixed mount (3) washes trigger structure and reading mechanism (7), described trigger structure of washing comprises cleaning head module (4) and hair washing transmission module, and described hair washing transmission module comprises the eccentric wheel drive mechanism (5) that control fluid suction head (8) moves up and down and the synchronous belt drive mechanism (6) controlling to wash the horizontal movement of trigger structure; Described workbench (1) is provided with the ELISA Plate put area with incubation function, and described ELISA Plate put area can place at least one ELISA Plate (2); It is characterized in that: described eccentric wheel drive mechanism comprises motor (16), code-disc (17), eccentric wheel (18), transmission device and driven pulley (21), described motor (16) is arranged on motor plate (15) side, described code-disc (17) is fixedly connected with eccentric wheel (18) and is arranged on described motor plate (15) opposite side, and the motor shaft of described motor (16) is fastening by jackscrew through the centre bore of described eccentric wheel (18); The eccentric orfice of described eccentric wheel (18) is provided with driven pulley (21), four angles of described motor plate (15) is respectively equipped with a driven pulley (21), described driven pulley (21) is fixed on described motor plate (15) by axle (22); Described transmission device is the driving member (19) that can slide up and down along with described eccentric wheel (18).
2. Enzyme-linked washing-board mechanism as claimed in claim 1, it is characterized in that: in the middle of described driving member (19) and both sides are provided with gathering sill, gathering sill in the middle of this driving member (19) is through the driven pulley (21) on eccentric wheel (18), and the gathering sill of this driving member (19) both sides coordinates with the driven pulley (21) on both sides respectively; Described driving member (19) is provided with drive link, and described drive link one end is installed on described driving member (19), and the other end inserts in the hole in the middle of hair washing driving member (11) through cover plate (13).
3. Enzyme-linked washing-board mechanism as claimed in claim 2, it is characterized in that: described motor plate (15) is provided with the photoelectric sensor (20) rotated by motor described in electric control system controls (16), the gap in the middle of this photoelectric sensor (20) is through described code-disc (17).
4. Enzyme-linked washing-board mechanism as claimed in claim 1, is characterized in that: the guard shield (10) that described cleaning head module (4) comprises fluid suction head (8), filling head (9) and both linked together; The upper end of described fluid suction head (8) has inverted T shape gathering sill, is inserted with I shape hair washing driving member (11) in described inverted T shape gathering sill; Described I shape hair washing driving member (11) lower end is inserted in described inverted T shape gathering sill, and upper end is connected with described fluid suction head (8) by the spring (12) that two are in compressive state all the time.
5. Enzyme-linked washing-board mechanism as claimed in claim 4, is characterized in that: it is inner that described fluid suction head (8) is arranged on described guard shield (10), and described fluid suction head (8) is provided with the cover plate (13) that this fluid suction head (8) can only be moved up and down; Described filling head (9) is arranged on described guard shield (10) by screw; Described fluid suction head (8) is provided with aspirating needle, and described filling head (9) is provided with injection needle, keeps fixing distance between described aspirating needle and described injection needle.
6. Enzyme-linked washing-board mechanism as claimed in claim 5, is characterized in that: described cleaning head module (4) is fixed on described motor plate (15) by two support columns (14), and described motor plate (15) is arranged on described fixed mount (3) by screw.
7. Enzyme-linked washing-board mechanism as claimed in claim 1, is characterized in that: described synchronous belt drive mechanism (6) comprises the guide rail (24) be fixed under described workbench (1), the reading mechanism (7) that is fixed together with Timing Belt (28) and the roller (23) that can roll along described guide rail (24).
8. Enzyme-linked washing-board mechanism as claimed in claim 7, it is characterized in that: described reading mechanism (7) is arranged on described fixed mount (3) by screw, described reading mechanism (7) is built with the electro-optical system of enzyme mark reading, four angles, described reading mechanism (7) bottom are separately installed with can step up guide rail (24) and along the roller (23) of guide rail (24) outside horizontal movement, the axle of described roller (23) is arranged on described reading mechanism (7) by screw; Described guide rail (24) two ends are arranged on described workbench (1) bottom and the holder be provided with for supporting this guide rail (24).
9. Enzyme-linked washing-board mechanism as claimed in claim 8, it is characterized in that: the Timing Belt (28) that degree of tightness is adjustable is fixed on the bottom of described reading mechanism (7), two ends are enclosed within synchronous pulley (26) and Timing Belt driven pulley (29) respectively; Fastening with jackscrew on the axle that described synchronous pulley (26) is arranged on stepper motor (25); Described guide rail (24) is provided with the catch (27) for photoelectricity location, photoelectric sensor (20) is positioned by the gap in the described catch of induction (27).
CN201310098559.8A 2013-03-26 2013-03-26 Enzyme-labeling washing plate mechanism Active CN103230902B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201310098559.8A CN103230902B (en) 2013-03-26 2013-03-26 Enzyme-labeling washing plate mechanism

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Application Number Priority Date Filing Date Title
CN201310098559.8A CN103230902B (en) 2013-03-26 2013-03-26 Enzyme-labeling washing plate mechanism

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CN103230902A CN103230902A (en) 2013-08-07
CN103230902B true CN103230902B (en) 2015-07-08

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Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109107954A (en) * 2018-08-15 2019-01-01 烟台艾德康生物科技有限公司 A kind of board-washing device of optional ELISA Plate hole location cleaning

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2816812Y (en) * 2005-09-07 2006-09-13 张传国 Efficient enzyme mark plate-washing machine
CN101782588A (en) * 2010-01-27 2010-07-21 苏州生物医学工程技术研究所 Double-needle sample sucking mechanism applicable to full-automatic blood type analytical instrument
CN201845017U (en) * 2010-10-21 2011-05-25 河北科技大学 Sample adding and plate washing integrated device
CN102095625A (en) * 2011-01-27 2011-06-15 桂林优利特医疗电子有限公司 Blending device of blood cell analyzer
CN203124349U (en) * 2013-03-26 2013-08-14 山东博科生物产业有限公司 Elisa plate washing mechanism

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2816812Y (en) * 2005-09-07 2006-09-13 张传国 Efficient enzyme mark plate-washing machine
CN101782588A (en) * 2010-01-27 2010-07-21 苏州生物医学工程技术研究所 Double-needle sample sucking mechanism applicable to full-automatic blood type analytical instrument
CN201845017U (en) * 2010-10-21 2011-05-25 河北科技大学 Sample adding and plate washing integrated device
CN102095625A (en) * 2011-01-27 2011-06-15 桂林优利特医疗电子有限公司 Blending device of blood cell analyzer
CN203124349U (en) * 2013-03-26 2013-08-14 山东博科生物产业有限公司 Elisa plate washing mechanism

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