CN103238593B - Stabilizing agent composition of pesticide liquid preparation and application - Google Patents
Stabilizing agent composition of pesticide liquid preparation and application Download PDFInfo
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Abstract
The invention provides a stabilizing agent composition of a pesticide liquid preparation. The composition comprises glacial acetic acid and alkylbenzene sulfonate in a mass ratio of (1:1)-(1:8). The composition accounts for 0.1-0.6% of the liquid preparation. Added to the pesticide liquid preparation, the stabilizing agent composition can effectively reduce the decomposition rates of effective components of the preparation, improve the stability of the preparation, especially reduce the rates of decomposition, caused by transposition, of the pesticide components with chiral structures and ensure the quality stability of the liquid preparation product. The stabilizing agent is easy in obtainment of raw materials, simple in production operation, low in usage amount and low in cost.
Description
Technical field
The present invention relates to technical field of pesticide, being specifically related to a kind of stabiliser compositions for preventing pesticide liquid body preparation active ingredient from decomposing.
Background technology
Agricultural chemicals, as the most important means ensureing agricultural production, grain security, is absolutely necessary.Pesticide active ingredient can be made into various formulation through specific processing technology, and pesticidal preparations is distinguished from kenel can divide solid pharmaceutical preparation and liquid preparation.Pesticide liquid body preparation is exactly the general designation that a class is the formulations of pesticide of fluid state, and it comprises missible oil, suspending agent, microemulsion, aqueous emulsion, low capacity liquor and ultra low volume liquids etc.
The bin stability of pesticidal preparations is pesticide standard and the important indicator weighing product quality, is also the guarantee that agricultural chemicals in use can give full play to drug effect.But large portion pesticide active ingredient, as common organic phosphor, chrysanthemum ester class, nicotinoids, carbamate and the former medicine of various heterocyclic, these active ingredients are taking short chain alcohol as the formulation of solvent and easily alcoholysis and hydrolysis are occurring in the water base chemical preparations taking water as solvent, liquid preparation particularly containing chiral structure agricultural chemicals, easy generation transposition decomposing phenomenon, active isomer is converted into poor efficiency body and loses activity, and as gamma cyhalothrin, (structure is
) (Z) 1R3R α S isomer biologically active is the highest in this active ingredient, (Z) 1S3S α R then non-activity, in pesticide liquid body preparation, often α-C isomerization easily occurring, is that active low (Z) 1R3R α S or (Z) 1S3S α R transfers (Z) 1S3S α S isomer phenomenon to by active isomer (Z) 1R3R α S transposition; (structure is indoxacarb
), in this active ingredient, only (DPX-KN128) S isomer has activity, and (DPX-KN127) R isomer does not have activity, and in pesticide liquid body preparation, position easily isomerization occurs indoxacarb chiral carbon, and S body is converted into R and loses activity.
Decompose and reduction activity in view of pesticide liquid body preparation active ingredient is subject to various factors impact, thus prevent active ingredient from decomposing, pesticidal preparations active ingredient stable in storing is kept to be the difficult point of technical field of pesticide research, pesticidal preparations scholar has studied some stabilizing agents for active ingredient in stable pesticide liquid body preparation, but the price of these stabilizing agents is too high or the scope of application is not wide etc. not enough, limit its application in pesticide liquid body preparation.At present, the method solving pesticide liquid body preparation stability problem conventional adds a certain amount of glacial acetic acid in the formulation, the method uses the amount of glacial acetic acid larger, the former medicine kind be suitable for is few, in-and-out fluctuation appears in stablizing effect, namely due to the reason of the factor fluctuations such as raw material quality, technique and environment, even if add identical amount glacial acetic acid, still there is the problem that effective ingredient breakdown rate is bigger than normal in the product of some batch.Therefore in the urgent need to a kind of stabiliser compositions of pesticide liquid body preparation, to solve the various instability problem existing for prior art Pesticides liquid preparation active ingredient.
Summary of the invention
For above-mentioned defect, the object of this invention is to provide a kind of stabiliser compositions of pesticide liquid body preparation, can realize Multiple Pesticides active component with short chain alcohol as the liquid preparation of solvent and with water be solvent water base chemical preparation in keep stable, reduce active ingredient to decompose, particularly prevent the phenomenon with chiral structure agricultural chemicals (as pyrethrin pesticide, metalaxyl, indoxacarb etc.) active ingredient transposition decomposition and inefficacy.
Above-mentioned purpose of the present invention is achieved by the following technical solution:
A stabiliser compositions for pesticide liquid body preparation, is characterized in that this stabiliser compositions is made up of glacial acetic acid and alkylbenzenesulfonate, and composition is 0.1%-0.6% in pesticide liquid body preparation mass percent.Wherein said glacial acetic acid mass percent in pesticide liquid body preparation is 0.05% ~ 0.3%; Alkylbenzenesulfonate mass percent in pesticide liquid body preparation is 0.05% ~ 0.5%.
In the present invention, unless there are specified otherwise, described percentage is mass percent.
In the stabiliser compositions of described pesticide liquid body preparation, the mass ratio of glacial acetic acid and alkylbenzenesulfonate is 1: 1 ~ 1: 8.
As preferably, in the stabiliser compositions of pesticide liquid body preparation of the present invention, the mass ratio of glacial acetic acid and alkylbenzenesulfonate is 1: 3 ~ 1: 6.
As more preferably, in the stabiliser compositions of pesticide liquid body preparation of the present invention, the mass ratio of glacial acetic acid and alkylbenzenesulfonate is 1: 5.
Described sulphophenyl sulfonate is for being one in sodium alkyl benzene sulfonate, alkyl benzene calcium sulfonate, magnesium alkylbenzene sulfonate.
A using method for pesticide liquid body preparation stabiliser compositions, mixes stabilizing agent with pesticide liquid body preparation, and the formulation of preferred described liquid preparation is missible oil, suspending agent, microemulsion, aqua, aqueous emulsion, ultra low volume liquids; Described pesticide activity component is pyrethrin pesticide and other farm chemical ingredients containing chiral structure.
As preferably, described pyrethrin pesticide composition be gamma cyhalothrin, sumicidin, beta-cypermethrin any one; Containing chiral structure farm chemical ingredients be indoxacarb, clodinafop-propargyl, metalaxyl any one.
Described auxiliary agent is at least one in polyoxyethylene nonylphenol ether, fatty alcohol-polyoxyethylene ether graft copolymer, tristyrylphenol polyoxyethylene ether, castor oil polyoxyethylene ether, thermally coupled distillation columns, fatty alcohol-polyoxyethylene ether and APG.
The stabiliser compositions of pesticide liquid body preparation of the present invention is applied to the pesticide liquid body preparations such as missible oil, suspending agent, microemulsion, aqua, aqueous emulsion, ultra low volume liquids.
Another object of the present invention is also to provide a kind of pesticide liquid body preparation comprising aforementioned stable agent composition.
In example of the present invention, 2.5% efficient cyhalothrin emulsifiable concentrate selects stabiliser compositions to be glacial acetic acid and alkyl benzene calcium sulfonate, and the best stabilizer composition quality percentage when both mass ratioes are 1: 1 is 0.1 ~ 0.5%.
In another instantiation of the present invention, 10% indoxacarb suspending agent selects stabiliser compositions to be glacial acetic acid and magnesium alkylbenzene sulfonate, and the best stabilizer composition quality percentage when both mass ratioes are 1: 3 is 0.1 ~ 0.6%.
In another instantiation of the present invention, it is glacial acetic acid and alkyl benzene calcium sulfonate that 15% fenvalerate aqueous emulsion selects stabiliser compositions to be stabiliser compositions, and the best stabilizer composition quality percentage when both mass ratioes are 1: 5 is 0.2 ~ 0.6%.
In another instantiation of the present invention, 10% Clodinafop-propargyl microemulsion selects stabiliser compositions to be glacial acetic acid and alkyl benzene calcium sulfonate, and the best stabilizer composition quality percentage when both mass ratioes are 1: 6 is 0.1 ~ 0.5%.
In another instantiation of the present invention, 20% metalaxyl aqua selects stabiliser compositions to be glacial acetic acid and sodium alkyl benzene sulfonate, and the best stabilizer composition quality percentage when mass ratio is 1: 8 is 0.2 ~ 0.5%.
In another instantiation of the present invention, 20% cypermethrin ultra low volume liquids selects stabiliser compositions to be glacial acetic acid and magnesium alkylbenzene sulfonate, and the best stabilizer composition quality percentage when both mass ratioes are 1: 5 is 0.1 ~ 0.6%.
The present invention possesses following beneficial effect:
(1) the present inventor is found by research, and organic acid is free H in pesticidal preparations
+concentration range 0.00001 ~ 0.001mol/L can ensure the stable of active ingredient, and organic acid dissociation constant is larger, is more conducive to stable pesticide activity component, i.e. organic acid releasable free H in pesticide liquid body preparation
+concentration is larger, is more conducive to ensureing that pesticide activity component is stablized, glacial acetic acid due to self-ionization constant little, dissociation constant (25 DEG C) Ka=1.74 × 10
-5, releasable free H
+concentration is low, need add the object that a large amount of glacial acetic acids just can play stable pesticide activity component.Alkylbenzenesulfonate and glacial acetic acid form glacial acetic acid salt and generation " salt effect " in liquid preparation, significantly improve glacial acetic acid and to dissociate H
+concentration also reaches the effect of stable pesticide activity component, deposits in case at alkylbenzenesulfonate, and reduce glacial acetic acid consumption and also can reach the effect stablize active ingredient preferably, namely both are combined in pesticide liquid body preparation the effect having and work in coordination with and stablize active ingredient.The consumption of this stabiliser compositions is less, and cost is lower, better effects if.
(2) pesticide variety is applied widely, and all can use in variety classes active ingredient, the agricultural chemicals stablizing effect particularly with chiral structure is better.
(3) adaptability is good, steady quality; The product of some batch will be caused to occur the problem that effective ingredient breakdown rate is bigger than normal because of factor fluctuations such as raw material quality, technique and environment.
Embodiment
Below in conjunction with specific embodiment, the invention will be further described, but be not limitation of the invention.
Test method and step: added according to a certain percentage in liquid preparation to be uniformly mixed by stabilizing agent and obtain sample, before being divided into heat storage, heat storage (54 ± 2 DEG C) and storage at normal temperature three samples by sample.
After sample is configured, sample active constituent content before carrying out storage at normal temperature immediately and measuring storage; Heat is store sample and puts into baking oven, design temperature is 54 ± 2 DEG C; Place after 14 days, detection level.Relative rate of resolution is calculated in contrast to store the front content measured, heat storage resolution ratio≤5% is qualified, after heat storage detection is qualified, placement normal temperature is observed to the sample of 2 years, time is respectively 3 months, 6 months, 12 months, 18 months and 24 months sample analysis active ingredient resolution ratio situations, judge that whether ageing stability is qualified.And for 14 days heat storage resolution ratio underproof, normal temperature sample no longer carries out 3 months, 6 months, 12 months, 18 months and 24 menstruations time stability test.Calculate resolution ratio in contrast to store the front content measured, heat storage and rear resolution ratio≤5% of normal temperature ageing stability storage are qualified.
Resolution ratio computing formula: resolution ratio %=(stores front content-Re and stores or content after normal temperature storage) front content × 100% of/storage
The reagent used in embodiment and medicine are commercially available prod, and former medicine used measures according to folding hundred.
Embodiment 1:
Gamma cyhalothrin 2.5kg, polyoxyethylene nonylphenol ether 60kg, dimethylbenzene 25kg, stabiliser compositions 0.2kg, methyl alcohol complements to 100 kg.Above raw material weighing joined well in stirred vessel, stir 30 minutes, obtain sample 1 i.e. 2.5% efficient cyhalothrin emulsifiable concentrate.Stabiliser compositions used is glacial acetic acid and alkyl benzene calcium sulfonate, and mass ratio is 1: 1 sample.
Stabiliser compositions addition may also be arbitrary numerical value of 0.1 ~ 0.6kg, obtains other samples according to the preparation technology identical with embodiment 1
Comparative example 1:
Take gamma cyhalothrin 2.5kg, polyoxyethylene nonylphenol ether 60kg, dimethylbenzene 25kg, add glacial acetic acid as stabilizing agent, addition is 0.8kg, and methyl alcohol complements to 100 kg.Comparative sample 1 is obtained according to the preparation technology identical with embodiment 1.
Glacial acetic acid addition may also be arbitrary numerical value of 0.1 ~ 0.9kg, obtains other comparative sample.
Above sample, carries out storing front assay, the test of normal temperature ageing stability and heating storage simultaneously, heat storage sample in an oven design temperature be 54 ± 2 DEG C place 14 days, normal temperature sample places 3,6,12,18 and 24 months respectively.Adopt high performance liquid chromatography to the normal temperature of sample, heat storage sample and Different periods before storage through time store sample in the content of gamma cyhalothrin measure, and calculate its resolution ratio, measurement result is in table 1.
test data in table all gets more than 10 times result of the test mean values.
The stability test result of table 1 2.5% efficient cyhalothrin emulsifiable concentrate
。
In table, the sample of embodiment 1 and comparative example 1 is at the rear relative rate of resolution of heat storage higher than 5%, and defective, then do not carry out storage at normal temperature test, in table, "-" indicates without test data.
Above result of the test shows, in 2.5% efficient cyhalothrin emulsifiable concentrate, add stabiliser compositions 0.1 ~ 0.5% can make the gamma cyhalothrin in preparation keep stable, its resolution ratio is all less than 5%, relative to the usage amount of alone glacial acetic acid 0.8%, this stabiliser compositions amount ranges is wider, better adaptability, is easy to operation in actual production.
Example 2: take indoxacarb 10kg, thermally coupled distillation columns 1kg, fatty alcohol-polyoxyethylene ether graft copolymer 3kg, aluminium-magnesium silicate 1kg, xanthans 0.2kg, ethylene glycol 3kg, stabiliser compositions 0.5kg, water complements to 100 kg.Above raw material weighing is well first added homogenizer high speed shear 10 minutes, after to join in sand mill, grinding 1 hour, obtain 10% indoxacarb suspending agent.Be glacial acetic acid and alkyl benzene sulphonate acid magnesium in stabiliser compositions, mass ratio is 1: 3 sample.
Stabiliser compositions addition may also be arbitrary numerical value of 0 ~ 0.7kg, obtains other samples according to the preparation technology identical with embodiment 2.
Comparative example 2:
Take indoxacarb 10kg, thermally coupled distillation columns 1kg, fatty alcohol-polyoxyethylene ether graft copolymer 3%, aluminium-magnesium silicate 1kg, xanthans 0.2kg, ethylene glycol 3kg, add glacial acetic acid 0.7kg, prepare sample.According to the preparation technology identical with embodiment 2, prepare other comparative sample.
Glacial acetic acid addition may also be arbitrary numerical value of 0.1 ~ 0.9kg, obtains other comparative sample.
Above sample, carries out storing front assay, the test of normal temperature ageing stability and heating storage simultaneously, heat storage sample in an oven design temperature be 54 ± 2 DEG C place 14 days, normal temperature sample places 3,6,12,18 and 24 months respectively.Adopt high performance liquid chromatography to the normal temperature of sample, heat storage sample and Different periods before storage through time store sample in the content of indoxacarb measure, and calculate resolution ratio, measurement result is in table 2.
test data in table all gets more than 10 times result of the test mean values.
Table 2 10% indoxacarb suspensions stability is tested.
。
In table, the sample of embodiment 2 and comparative example 2 is at the rear relative rate of resolution of heat storage higher than 5%, and defective, then do not carry out storage at normal temperature test, in table, "-" indicates without test data.
Above result of the test shows, in 10% indoxacarb suspending agent, add stabiliser compositions 0.1 ~ 0.6% can make the indoxacarb in preparation keep stable, relative to the usage amount of alone glacial acetic acid 0.7 ~ 0.8%, this stabiliser compositions amount ranges is wider, adaptability is wider, is easy to operation in actual production.
Example 3: by sumicidin 15kg, cyclohexanone 5kg, dimethylbenzene 10kg, isopropyl alcohol 3kg, tristyrylphenol polyoxyethylene ether 3kg, fatty alcohol-polyoxyethylene ether graft copolymer 1 kg, castor oil polyoxyethylene ether 1 kg, former for sumicidin medicine also dissolves completely by mix and blend, adds load weighted stabiliser compositions 0.4kg, obtain oil phase, water is complemented to 100 kg.Use homogenizer to carry out high speed shear 10 minutes above raw material, obtain 15% fenvalerate aqueous emulsion.Stabiliser compositions is glacial acetic acid and sodium alkyl benzene sulfonate, and mass ratio is 1: 5 sample.
Stabiliser compositions addition may also be arbitrary numerical value of 0 ~ 0.7kg, obtains other samples according to the preparation technology identical with embodiment 3.
Comparative example 3:
By sumicidin 15kg, cyclohexanone 5kg, dimethylbenzene 10kg, isopropyl alcohol 3kg, tristyrylphenol polyoxyethylene ether 3kg, fatty alcohol-polyoxyethylene ether graft copolymer 1 kg, castor oil polyoxyethylene ether 1 kg, former for sumicidin medicine also dissolves completely by mix and blend, adds glacial acetic acid 0.7kg, according to the preparation technology identical with embodiment 3, prepare sample.
Glacial acetic acid addition may also be arbitrary numerical value of 0.1 ~ 0.9kg, obtains other comparative sample.
Above sample, carries out storing front assay, the test of normal temperature ageing stability and heating storage simultaneously, heat storage sample in an oven design temperature be 54 ± 2 DEG C place 14 days, normal temperature sample places 3,6,12,18 and 24 months respectively.Adopt gas chromatography to the normal temperature of sample, heat storage sample and Different periods before storage through time store sample in sumicidin measure, and calculate resolution ratio, measurement result is in table 3;
test data in table all gets more than 10 times result of the test mean values.
Table 3 15% fenvalerate aqueous emulsion stability experiment.
。In table, the sample of embodiment 3 and comparative example 3 is at the rear relative rate of resolution of heat storage higher than 5%, and defective, then do not carry out storage at normal temperature test, in table, "-" indicates without test data.
Above result of the test shows, add stabiliser compositions 0.2 ~ 0.6% and the sumicidin in preparation can be made to keep stable, and alone glacial acetic acid 0.1 ~ 0.9% all can not make sumicidin stablize in 15% fenvalerate aqueous emulsion.This stabiliser compositions amount ranges is wider, and adaptability is wider, and the better adaptability of former medicine is easy to operation in actual production
Example 4: take clodinafop-propargyl 10kg, cyclohexanone 10kg, n-butanol 5kg, ethyl acetate 3kg, tristyrylphenol polyoxyethylene ether 10kg, polyoxyethylene nonylphenol ether 5 kg, fatty alcohol-polyoxyethylene ether 5 kg, adds load weighted stabiliser compositions 0.3kg, first clodinafop-propargyl is dissolved by above raw material after being fully formed oil phase, add water and complement to 100 kg, obtain 10% Clodinafop-propargyl microemulsion.Stabiliser compositions is glacial acetic acid and alkyl benzene calcium sulfonate, and mass ratio is 1: 6 sample.
Stabiliser compositions addition may also be arbitrary numerical value of 0 ~ 0.7kg, obtains other samples according to the preparation technology identical with embodiment 4.
Comparative example 4:
Take clodinafop-propargyl 10kg, cyclohexanone 10kg, n-butanol 5kg, ethyl acetate 3kg, tristyrylphenol polyoxyethylene ether 10 kg, polyoxyethylene nonylphenol ether 5 kg, fatty alcohol-polyoxyethylene ether 5 kg, adds glacial acetic acid 0.9kg, according to the preparation technology identical with embodiment 4, preparation comparative sample
Glacial acetic acid addition may also be arbitrary numerical value of 0.1 ~ 1kg, obtains other comparative sample.
Above sample, carries out storing front assay, the test of normal temperature ageing stability and heating storage simultaneously, heat storage sample in an oven design temperature be 54 ± 2 DEG C place 14 days, normal temperature sample places 3,6,12,18 and 24 months respectively.Adopt high performance liquid chromatography to the normal temperature of sample, heat storage sample and Different periods before storage through time store sample in the content of clodinafop-propargyl measure, and calculate its resolution ratio, measurement result is in table 4.
test data in table all gets more than 10 times result of the test mean values.
Table 4 10% Clodinafop-propargyl microemulsion stability experiment
。
In table, the sample of embodiment 4 and comparative example 4 is at the rear relative rate of resolution of heat storage higher than 5%, and defective, then do not carry out storage at normal temperature test, in table, "-" indicates without test data.
Above result of the test shows, adds stabiliser compositions 0.1 ~ 0.5% in 10% Clodinafop-propargyl microemulsion, and the clodinafop-propargyl in preparation can be made to keep stable, relative to the usage amount of alone glacial acetic acid 0.9%.This stabiliser compositions amount ranges is wider, and adaptability is wider, is easy to operation in actual production.
Example 5: by metalaxyl 20kg, ethanol 20kg, water 20kg, mixing, dissolve metalaxyl completely, add APG 8kg, load weighted stabiliser compositions 0.4 kg, adds water and complements to 100 kg, obtains 20% metalaxyl aqua.Stabiliser compositions is glacial acetic acid and sodium alkyl benzene sulfonate, and mass ratio is 1: 8 sample.
Stabiliser compositions addition may also be arbitrary numerical value of 0 ~ 0.6kg, obtains other samples according to the preparation technology identical with embodiment 5.
Comparative example 5:
Just metalaxyl 20kg, ethanol 20kg, water 20kg, mix and blend, dissolves metalaxyl completely, adds APG 8kg, load weighted stabiliser compositions 0.7 kg, according to the preparation technology identical with embodiment 5, preparation comparative sample.
Glacial acetic acid addition may also be arbitrary numerical value of 0.1 ~ 0.9kg, obtains other comparative sample.
Above sample, carries out storing front assay, the test of normal temperature ageing stability and heating storage simultaneously, heat storage sample in an oven design temperature be 54 ± 2 DEG C place 14 days, normal temperature sample places 3,6,12,18 and 24 months respectively.Adopt gas chromatography to the normal temperature of sample, heat storage sample and Different periods before storage through time store sample in the content of metalaxyl measure, and calculate resolution ratio, measurement result is in table 5.
test data in table all gets more than 10 times result of the test mean values.
Table 5 20% metalaxyl aqua stability experiment.
。
In table, the sample of embodiment 5 and comparative example 5 is at the rear relative rate of resolution of heat storage higher than 5%, and defective, then do not carry out storage at normal temperature test, in table, "-" indicates without test data.
Above result of the test shows, add stabiliser compositions 0.2 ~ 0.5% and the metalaxyl in preparation can be made to keep stable, and alone glacial acetic acid consumption 0.1 ~ 1kg can not make metalaxyl keep stable in 20% metalaxyl aqua.This stabiliser compositions amount ranges is wider, and adaptability is wider, is easy to operation in actual production.
Example 6: take cypermethrin 20kg, tristyrylphenol polyoxyethylene ether 8kg, fatty alcohol-polyoxyethylene ether 8 kg, No. 200 solvent naphtha 30 kg, stabiliser compositions 0.3kg, methyl oleate complements to 100 kg, add reactor and stir 30 minutes, obtain 20% cypermethrin ultra low volume liquids.Stabiliser compositions is glacial acetic acid and magnesium alkylbenzene sulfonate, and mass ratio is 1: 5 sample.
Stabiliser compositions addition may also be arbitrary numerical value of 0 ~ 0.7kg, obtains other samples according to the preparation technology identical with embodiment 6.
Comparative example 6:
Take cypermethrin 20kg, tristyrylphenol polyoxyethylene ether 8kg, fatty alcohol-polyoxyethylene ether 8 kg, No. 200 solvent naphtha 30 kg, add glacial acetic acid 0.9kg, according to the preparation technology identical with embodiment 6, and preparation comparative sample.
Glacial acetic acid addition may also be arbitrary numerical value of 0.1 ~ 1kg, obtains other comparative sample.
Above sample, carries out storing front assay, the test of normal temperature ageing stability and heating storage simultaneously, heat storage sample in an oven design temperature be 54 ± 2 DEG C place 14 days, normal temperature sample places 3,6,12,18 and 24 months respectively.Adopt high performance liquid chromatography to the normal temperature of sample, heat storage sample and Different periods before storage through time store sample in the content of cypermethrin measure, and calculate its resolution ratio, measurement result is in table 6.
test data in table all gets more than 10 times result of the test mean values.
Table 6 20% cypermethrin ultra low volume liquids stability experiment.
。
In table, the sample of embodiment 6 and comparative example 6 is at the rear relative rate of resolution of heat storage higher than 5%, and defective, then do not carry out storage at normal temperature test, in table, "-" indicates without test data.
Above result of the test shows, in 20% cypermethrin ultra low volume liquids, add stabiliser compositions 0.1 ~ 0.6% can make the cypermethrin in preparation keep stable, and alone glacial acetic acid need add 0.9%, but glacial acetic acid is added or is added less, all affect stable effective ingredients, heat storage resolution ratio is all defective.So it is few to do stabiliser compositions consumption of the present invention, amount ranges is wider, and adaptability is wider, is easy to operation in actual production.
Claims (7)
1. a stabiliser compositions for pesticide liquid body preparation, is characterized in that this stabiliser compositions is made up of glacial acetic acid and alkylbenzenesulfonate, and composition is 0.1%-0.6% in pesticide liquid body preparation mass percent; Wherein glacial acetic acid mass percent in pesticide liquid body preparation is 0.05% ~ 0.3%; Alkylbenzenesulfonate mass percent in pesticide liquid body preparation is 0.05% ~ 0.5%; Wherein the mass ratio of glacial acetic acid and alkylbenzenesulfonate is 1:1,1:3,1:5,1:6,1:8.
2., according to the stabiliser compositions of pesticide liquid body preparation described in claim 1, it is characterized in that described alkylbenzenesulfonate is a kind of in sodium alkyl benzene sulfonate, alkyl benzene calcium sulfonate, magnesium alkylbenzene sulfonate.
3. the using method of the stabiliser compositions of pesticide liquid body preparation as described in any one of claim 1-2, is characterized in that it is uniformly mixed when preparing pesticide liquid body preparation by described stabilizing agent together with pesticide activity component, auxiliary agent, solvent; Wherein pesticide activity component is pyrethrin pesticide composition and other farm chemical ingredients containing chiral structure; Described pyrethrin pesticide composition be gamma cyhalothrin, sumicidin, beta-cypermethrin any one; The described farm chemical ingredients containing chiral structure be indoxacarb, clodinafop-propargyl, metalaxyl any one.
4. using method according to claim 3, is characterized in that described auxiliary agent is at least one in polyoxyethylene nonylphenol ether, fatty alcohol-polyoxyethylene ether graft copolymer, tristyrylphenol polyoxyethylene ether, castor oil polyoxyethylene ether, thermally coupled distillation columns, fatty alcohol-polyoxyethylene ether and APG.
5. the pesticide liquid body preparation that using method is obtained according to any one of claim 3-4.
6. pesticide liquid body preparation according to claim 5, its formulation is missible oil, suspending agent, microemulsion, aqua, aqueous emulsion, ultra low volume liquids.
7. the stabiliser compositions described in any one of claim 1-2 prepare pyrethrin pesticide and other containing chiral structure pesticidal preparations in application, described pyrethrin pesticide composition be gamma cyhalothrin, sumicidin, beta-cypermethrin any one, the described farm chemical ingredients containing chiral structure be indoxacarb, clodinafop-propargyl, metalaxyl any one.
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| CN101442907A (en) * | 2005-12-22 | 2009-05-27 | Fmc有限公司 | Novel formulations of bifenthrin and enriched cypermethrin |
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| CN102630666A (en) * | 2012-04-10 | 2012-08-15 | 山东荣邦化工有限公司 | Emulsion-in-water insecticide and production process thereof |
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| CN103004804A (en) * | 2012-11-26 | 2013-04-03 | 安徽农业大学 | Thifluzamide oil suspension and use and preparation method thereof |
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2013
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Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101442907A (en) * | 2005-12-22 | 2009-05-27 | Fmc有限公司 | Novel formulations of bifenthrin and enriched cypermethrin |
| CN102369957A (en) * | 2011-10-18 | 2012-03-14 | 浙江农林大学 | Multi-effect biological pesticide aqueous solution agent and preparation method and application thereof |
| CN102630666A (en) * | 2012-04-10 | 2012-08-15 | 山东荣邦化工有限公司 | Emulsion-in-water insecticide and production process thereof |
| CN103004804A (en) * | 2012-11-26 | 2013-04-03 | 安徽农业大学 | Thifluzamide oil suspension and use and preparation method thereof |
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