CN103190402A - Compound composition of 2-cyano-3-amino-3-phenyl ethyl acrylate and ethylicin and application thereof - Google Patents
Compound composition of 2-cyano-3-amino-3-phenyl ethyl acrylate and ethylicin and application thereof Download PDFInfo
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- CN103190402A CN103190402A CN2013101351833A CN201310135183A CN103190402A CN 103190402 A CN103190402 A CN 103190402A CN 2013101351833 A CN2013101351833 A CN 2013101351833A CN 201310135183 A CN201310135183 A CN 201310135183A CN 103190402 A CN103190402 A CN 103190402A
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- Prior art keywords
- cyano
- amino
- phenylancryic acetate
- ethyl ethylthio
- ethylthio sulfonate
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- OICGFSUWXCJLCO-UHFFFAOYSA-N 1-ethylsulfonylsulfanylethane Chemical compound CCSS(=O)(=O)CC OICGFSUWXCJLCO-UHFFFAOYSA-N 0.000 title claims abstract description 56
- 239000000203 mixture Substances 0.000 title claims abstract description 55
- 150000001875 compounds Chemical class 0.000 title abstract description 9
- PNJWIWWMYCMZRO-UHFFFAOYSA-N pent‐4‐en‐2‐one Natural products CC(=O)CC=C PNJWIWWMYCMZRO-UHFFFAOYSA-N 0.000 title abstract 6
- 239000000375 suspending agent Substances 0.000 claims abstract description 22
- 235000016623 Fragaria vesca Nutrition 0.000 claims abstract description 19
- 235000011363 Fragaria x ananassa Nutrition 0.000 claims abstract description 19
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 17
- 201000010099 disease Diseases 0.000 claims abstract description 16
- 241000082085 Verticillium <Phyllachorales> Species 0.000 claims abstract description 14
- 235000007164 Oryza sativa Nutrition 0.000 claims abstract description 12
- 241000209140 Triticum Species 0.000 claims abstract description 12
- 235000021307 Triticum Nutrition 0.000 claims abstract description 12
- 235000009566 rice Nutrition 0.000 claims abstract description 12
- 240000009088 Fragaria x ananassa Species 0.000 claims abstract 2
- 240000007594 Oryza sativa Species 0.000 claims abstract 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims description 52
- 239000003905 agrochemical Substances 0.000 claims description 25
- 238000002360 preparation method Methods 0.000 claims description 16
- 239000000843 powder Substances 0.000 claims description 14
- 238000009736 wetting Methods 0.000 claims description 13
- 206010039509 Scab Diseases 0.000 claims description 9
- 238000009472 formulation Methods 0.000 claims description 7
- 239000000575 pesticide Substances 0.000 abstract description 12
- 230000000694 effects Effects 0.000 abstract description 10
- 230000000844 anti-bacterial effect Effects 0.000 abstract description 9
- 239000002131 composite material Substances 0.000 abstract description 6
- 239000004480 active ingredient Substances 0.000 abstract description 4
- 230000002265 prevention Effects 0.000 abstract description 3
- 238000004519 manufacturing process Methods 0.000 abstract description 2
- -1 aryl phenol Chemical compound 0.000 description 32
- 238000012360 testing method Methods 0.000 description 20
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 19
- 241000220223 Fragaria Species 0.000 description 17
- 239000003814 drug Substances 0.000 description 15
- 241000209094 Oryza Species 0.000 description 10
- 239000003921 oil Substances 0.000 description 10
- 235000019198 oils Nutrition 0.000 description 10
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 9
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 9
- 239000000945 filler Substances 0.000 description 7
- 239000003995 emulsifying agent Substances 0.000 description 6
- 230000003449 preventive effect Effects 0.000 description 6
- 239000002904 solvent Substances 0.000 description 6
- 239000007788 liquid Substances 0.000 description 5
- 238000002791 soaking Methods 0.000 description 5
- UHPMCKVQTMMPCG-UHFFFAOYSA-N 5,8-dihydroxy-2-methoxy-6-methyl-7-(2-oxopropyl)naphthalene-1,4-dione Chemical compound CC1=C(CC(C)=O)C(O)=C2C(=O)C(OC)=CC(=O)C2=C1O UHPMCKVQTMMPCG-UHFFFAOYSA-N 0.000 description 4
- 239000005995 Aluminium silicate Substances 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 4
- 241000223218 Fusarium Species 0.000 description 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 4
- 235000012211 aluminium silicate Nutrition 0.000 description 4
- LLEMOWNGBBNAJR-UHFFFAOYSA-N biphenyl-2-ol Chemical compound OC1=CC=CC=C1C1=CC=CC=C1 LLEMOWNGBBNAJR-UHFFFAOYSA-N 0.000 description 4
- 239000006184 cosolvent Substances 0.000 description 4
- 239000013530 defoamer Substances 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 238000011835 investigation Methods 0.000 description 4
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 4
- 239000003960 organic solvent Substances 0.000 description 4
- 239000004576 sand Substances 0.000 description 4
- PYODKQIVQIVELM-UHFFFAOYSA-M sodium;2,3-bis(2-methylpropyl)naphthalene-1-sulfonate Chemical compound [Na+].C1=CC=C2C(S([O-])(=O)=O)=C(CC(C)C)C(CC(C)C)=CC2=C1 PYODKQIVQIVELM-UHFFFAOYSA-M 0.000 description 4
- 230000002195 synergetic effect Effects 0.000 description 4
- 239000002562 thickening agent Substances 0.000 description 4
- 241000196324 Embryophyta Species 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 3
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 3
- 150000001336 alkenes Chemical class 0.000 description 3
- 230000002528 anti-freeze Effects 0.000 description 3
- 239000003899 bactericide agent Substances 0.000 description 3
- 229920005551 calcium lignosulfonate Polymers 0.000 description 3
- RYAGRZNBULDMBW-UHFFFAOYSA-L calcium;3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Ca+2].COC1=CC=CC(CC(CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O RYAGRZNBULDMBW-UHFFFAOYSA-L 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical class CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 231100000419 toxicity Toxicity 0.000 description 3
- 230000001988 toxicity Effects 0.000 description 3
- 235000015112 vegetable and seed oil Nutrition 0.000 description 3
- 239000008158 vegetable oil Substances 0.000 description 3
- RNMDNPCBIKJCQP-UHFFFAOYSA-N 5-nonyl-7-oxabicyclo[4.1.0]hepta-1,3,5-trien-2-ol Chemical compound C(CCCCCCCC)C1=C2C(=C(C=C1)O)O2 RNMDNPCBIKJCQP-UHFFFAOYSA-N 0.000 description 2
- FRXSZNDVFUDTIR-UHFFFAOYSA-N 6-methoxy-1,2,3,4-tetrahydroquinoline Chemical compound N1CCCC2=CC(OC)=CC=C21 FRXSZNDVFUDTIR-UHFFFAOYSA-N 0.000 description 2
- SECXISVLQFMRJM-UHFFFAOYSA-N N-Methylpyrrolidone Chemical compound CN1CCCC1=O SECXISVLQFMRJM-UHFFFAOYSA-N 0.000 description 2
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 description 2
- RCEAADKTGXTDOA-UHFFFAOYSA-N OS(O)(=O)=O.CCCCCCCCCCCC[Na] Chemical compound OS(O)(=O)=O.CCCCCCCCCCCC[Na] RCEAADKTGXTDOA-UHFFFAOYSA-N 0.000 description 2
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 2
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 description 2
- 238000013019 agitation Methods 0.000 description 2
- 239000012752 auxiliary agent Substances 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- JHIVVAPYMSGYDF-UHFFFAOYSA-N cyclohexanone Chemical compound O=C1CCCCC1 JHIVVAPYMSGYDF-UHFFFAOYSA-N 0.000 description 2
- YDEXUEFDPVHGHE-GGMCWBHBSA-L disodium;(2r)-3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Na+].[Na+].COC1=CC=CC(C[C@H](CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O YDEXUEFDPVHGHE-GGMCWBHBSA-L 0.000 description 2
- LQZZUXJYWNFBMV-UHFFFAOYSA-N dodecan-1-ol Chemical class CCCCCCCCCCCCO LQZZUXJYWNFBMV-UHFFFAOYSA-N 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 235000011187 glycerol Nutrition 0.000 description 2
- 238000000227 grinding Methods 0.000 description 2
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- 230000000361 pesticidal effect Effects 0.000 description 2
- 229920000056 polyoxyethylene ether Polymers 0.000 description 2
- 229940051841 polyoxyethylene ether Drugs 0.000 description 2
- 229920001296 polysiloxane Polymers 0.000 description 2
- 238000010008 shearing Methods 0.000 description 2
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- 238000009331 sowing Methods 0.000 description 2
- 238000001228 spectrum Methods 0.000 description 2
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- GSEJCLTVZPLZKY-UHFFFAOYSA-O triethanolammonium Chemical class OCC[NH+](CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-O 0.000 description 2
- 230000017260 vegetative to reproductive phase transition of meristem Effects 0.000 description 2
- 239000004563 wettable powder Substances 0.000 description 2
- IJVRPNIWWODHHA-UHFFFAOYSA-N 2-cyanoprop-2-enoic acid Chemical compound OC(=O)C(=C)C#N IJVRPNIWWODHHA-UHFFFAOYSA-N 0.000 description 1
- JCUDAMKYTWVICI-UHFFFAOYSA-N 4-benzyl-2,3-dimethylphenol Chemical compound C1=C(O)C(C)=C(C)C(CC=2C=CC=CC=2)=C1 JCUDAMKYTWVICI-UHFFFAOYSA-N 0.000 description 1
- 235000001674 Agaricus brunnescens Nutrition 0.000 description 1
- JDLKFOPOAOFWQN-VIFPVBQESA-N Allicin Natural products C=CCS[S@](=O)CC=C JDLKFOPOAOFWQN-VIFPVBQESA-N 0.000 description 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 description 1
- 208000031968 Cadaver Diseases 0.000 description 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
- SNRUBQQJIBEYMU-UHFFFAOYSA-N Dodecane Natural products CCCCCCCCCCCC SNRUBQQJIBEYMU-UHFFFAOYSA-N 0.000 description 1
- 239000006000 Garlic extract Substances 0.000 description 1
- 206010023126 Jaundice Diseases 0.000 description 1
- WPPOGHDFAVQKLN-UHFFFAOYSA-N N-Octyl-2-pyrrolidone Chemical compound CCCCCCCCN1CCCC1=O WPPOGHDFAVQKLN-UHFFFAOYSA-N 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 150000004996 alkyl benzenes Chemical class 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- JDLKFOPOAOFWQN-UHFFFAOYSA-N allicin Chemical compound C=CCSS(=O)CC=C JDLKFOPOAOFWQN-UHFFFAOYSA-N 0.000 description 1
- 235000010081 allicin Nutrition 0.000 description 1
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000000440 bentonite Substances 0.000 description 1
- 229910000278 bentonite Inorganic materials 0.000 description 1
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 description 1
- ZCILODAAHLISPY-UHFFFAOYSA-N biphenyl ether Natural products C1=C(CC=C)C(O)=CC(OC=2C(=CC(CC=C)=CC=2)O)=C1 ZCILODAAHLISPY-UHFFFAOYSA-N 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000004927 clay Substances 0.000 description 1
- 239000007859 condensation product Substances 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 230000001934 delay Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 230000006806 disease prevention Effects 0.000 description 1
- 125000003438 dodecyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
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- YIAJIHKPSCGWLV-UHFFFAOYSA-N ethoxy-ethyl-oxo-sulfanylidene-$l^{6}-sulfane Chemical compound CCOS(=O)(=S)CC YIAJIHKPSCGWLV-UHFFFAOYSA-N 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 230000035558 fertility Effects 0.000 description 1
- 230000000855 fungicidal effect Effects 0.000 description 1
- 235000020706 garlic extract Nutrition 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 231100000053 low toxicity Toxicity 0.000 description 1
- 159000000003 magnesium salts Chemical class 0.000 description 1
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- LCRMGUFGEDUSOG-UHFFFAOYSA-N naphthalen-1-ylsulfonyloxymethyl naphthalene-1-sulfonate;sodium Chemical compound [Na].C1=CC=C2C(S(=O)(OCOS(=O)(=O)C=3C4=CC=CC=C4C=CC=3)=O)=CC=CC2=C1 LCRMGUFGEDUSOG-UHFFFAOYSA-N 0.000 description 1
- 239000011664 nicotinic acid Substances 0.000 description 1
- 230000010412 perfusion Effects 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
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- 229920001223 polyethylene glycol Polymers 0.000 description 1
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- 230000001018 virulence Effects 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a compound composition of 2-cyano-3-amino-3-phenyl ethyl acrylate and ethylicin and an application thereof, and belongs to the pesticide field. The compound composition provided by the invention comprises the active ingredients: 2-cyano-3-amino-3-phenyl ethyl acrylate and ethylicin, wherein the mass ratio of 2-cyano-3-amino-3-phenyl ethyl acrylate to ethylicin is (1-36):6; and the composite has not been reported at present. After the compound composition provided by the invention is prepared into a pesticide, the pesticide can be used for effectively preventing verticillium wilt of strawberry, bakanae disease of rice and gibberellic disease of wheat; the control effect of the pesticide is obvious and the use of missible oil is avoided; in relation to independent use of 2-cyano-3-amino-3-phenyl ethyl acrylate, the pesticide prepared from the compound composition is still capable of achieving control effect similar to that of 25% 2-cyano-3-amino-3-phenyl ethyl acrylate suspending agent, and the active ingredient ethylicin greatly reduces the production cost; besides, the compound bactericidal composition is capable of obviously improving the prevention and treatment effects and the dosage of the pesticide is reduced; therefore, the compound composition becomes an important tool for comprehensively preventing and treating various diseases.
Description
Technical field
The present invention relates to pesticide field, relate in particular to complex composition and the application of a kind of 2-cyano-3-amino-3-phenylancryic acetate and S-Ethyl ethylthio sulfonate.
Background technology
2-cyano-3-amino-3-phenylancryic acetate belongs to 2-cyanoacrylate bactericide, belongs to little malicious pesticide species.Former medicine outward appearance is the white solid powder.Chemical name: 2-cyano group-3-aminoacrylic acid ethyl ester.2-cyano-3-amino-3-phenylancryic acetate is effective to the disease that the reaping hook mushroom causes, has protective effect and therapeutic action.Be absorbed by root, at blade upwards transporting arranged, relatively poor towards leaf subordinate portion and interlobate transporting.The result shows through field control effectiveness test, and 25% 2-cyano-3-amino-3-phenylancryic acetate suspending agent has the better prevention effect to wheat scab.
S-Ethyl ethylthio sulfonate is antibacterial agent 402 again, and chemical name is: O-Ethyl ethanesulfonothioate, molecular formula: C
4H
10O
2S
2Missible oil is adopted in the use of S-Ethyl ethylthio sulfonate at present more, and 80% S-Ethyl ethylthio sulfonate missible oil is the most common.The missible oil formulation of S-Ethyl ethylthio sulfonate is especially easily by plant absorbing, so the disease prevention and cure effect is outstanding.The cost and price of S-Ethyl ethylthio sulfonate is compared cheap with other bactericide, be a kind of plant resource bionic pesticide, is the ethyl homologue of edible garlic extract allicin.Its bactericidal mechanism is to contain in (S-S=O=O) group and the thalline molecule in its molecular structure-substance reaction of SH base, thereby suppresses the thalline eubolism, and range of application is very extensive.
But with regard to China's existing market market, the use of organic solvent on agricultural chemicals is restricted day by day, need not or as far as possible few be the inexorable trend of agricultural chemicals development with organic solvent, national the Ministry of Industry and Information Technology has stopped accepting and has examined the emulsifiable concentrates for agricultural chemicals product.The change of the formulations of pesticide just develops along the good direction of efficient, low toxicity, safety and Environmental compatibility.
Summary of the invention
Goal of the invention: the purpose of this invention is to provide the complex composition of lasting, the lower-cost 2-cyano-3-amino-3-phenylancryic acetate of a kind of effect and S-Ethyl ethylthio sulfonate, can be used for being mixed with wide-spectrum bactericide; Another object of the present invention provides this complex composition for the preparation of the application on control strawberry verticillium wilt, bakanae disease of rice, the wheat scab, reduces the usage amount of organic solvent.
Technical scheme: the complex composition of a kind of 2-cyano-3-amino-3-phenylancryic acetate of the present invention and S-Ethyl ethylthio sulfonate, its effective active composition is 2-cyano-3-amino-3-phenylancryic acetate and S-Ethyl ethylthio sulfonate, the mass ratio of 2-cyano-3-amino-3-phenylancryic acetate and S-Ethyl ethylthio sulfonate is 1～36:6.
As preferred version of the present invention, the mass ratio of described 2-cyano-3-amino-3-phenylancryic acetate and S-Ethyl ethylthio sulfonate is 1～4:2.
As optimal case of the present invention, the mass ratio of described 2-cyano-3-amino-3-phenylancryic acetate and S-Ethyl ethylthio sulfonate is 1:1.
Complex composition of the present invention can effectively be prevented and treated some corps diseases by being mixed with corresponding agricultural chemicals, corresponding different diseases, and the 2-cyano-3-amino-3-phenylancryic acetate in the described complex composition and the proportioning of S-Ethyl ethylthio sulfonate are variant, but all can be mixed with wetting powder or suspending agent.
During the preparation wetting powder, by add auxiliary agent and filler in complex composition of the present invention, after the mixing, making ultra-fine wettable powder by airslide disintegrating mill can obtain.Comprise 2-cyano-3-amino-3-phenylancryic acetate 5%～30% by mass percentage, S-Ethyl ethylthio sulfonate 5%～30%, Ricinate 8%～20%, all the other are filler, comprise white carbon 4%～10% in the described filler.
The present invention is used for the described Ricinate of preparation wetting powder and includes but not limited to: any one of alkylnaphthalene sulfonate, dodecyl sodium sulfate, lauryl sodium sulfate, sodium lignin sulfonate, trisiloxanes polyethers, APG, sulfonic acid polyformaldehyde condensation product, calcium lignosulfonate, sodium methylene bis-naphthalene sulfonate, Nekal BX, ethoxylated dodecyl alcohol, aryl phenol APEO and dodecyl polyoxyethylene ether phosphate or sulfuric ester or multiple combination.
The present invention is used for any one or the multiple combination that the described filler of preparation wetting powder includes but not limited to white carbon, kaolin, bentonite, diatomite and potter's clay.
During the preparation suspending agent, complex composition of the present invention must be added solvent or cosolvent, emulsifier, be dissolved into even oil phase, again water, antifreeze, thickener, defoamer are mixed and be made into even water, under high-speed stirred and shearing force effect, water liquid is joined in the oil phase liquid, grind twice through sand mill, namely obtain the suspending agent of 2-cyano-3-amino-3-phenylancryic acetate S-Ethyl ethylthio sulfonate.More than the suspending agent of Huo Deing is ripe 2-cyano-3-amino-3-phenylancryic acetate S-Ethyl ethylthio sulfonate Pesticidal products, after packing, can effectively store, and plug and play, very easy to use.And the control efficiency of this suspending agent is better than wetting powder.
The agricultural chemicals of suspending agent formulation comprises following component by mass percentage: 2-cyano-3-amino-3-phenylancryic acetate 5%～30%, S-Ethyl ethylthio sulfonate 5%～30%, solvent and cosolvent 2%～20%, emulsifier 3%～10%, antifreezing agent 1%～5%, thickener 0.1%～1%, defoamer 0.1%～0.5%, water surplus.
Above-described solvent and cosolvent include but not limited to any one or the multiple combination in dimethyl formamide, ethylene glycol, propane diols, toluene, dimethylbenzene, ethanol, cyclohexanone, vegetable oil, N-methyl pyrrolidone, the N-octylpyrrolidone.
Above-described emulsifier comprises but is not limited in alkyl benzene calcium sulfonate, polyoxyethylene nonylphenol ether, phenyl phenol polyoxy ethyl ether phosphate, styrene polyoxyethylene ether ammonium sulfate salt, alkyl biphenyl ether disulfonic acid magnesium salts, tri ethanol ammonium salt, benzyl dimethyl phenol polyoxy ethyl ether, the phenyl phenol polyoxy ethyl ether etc. any one or multiple combination.
Above-described antifreeze includes but not limited in ethylene glycol, glycerine, propane diols, glycerine, polyethylene glycol or the sorbierite any one or multiple combination, uses that total consumption is no more than 1% when multiple.
Above-described thickener includes but not limited to any one or the multiple combination in xanthans, carboxymethyl cellulose, methylcellulose, Magnesiumaluminumsilicate, the polyvinyl alcohol.
Above-described defoamer includes but not limited to any one or the multiple combination in silicone oil, the silicone compound.
The agricultural chemicals that the complex composition of 2-cyano-3-amino-3-phenylancryic acetate of the present invention and S-Ethyl ethylthio sulfonate is made, when 2-cyano-3-amino-3-phenylancryic acetate and S-Ethyl ethylthio sulfonate mass ratio were 1:1, drug action was best.The present invention tests in the example 1, through the test of Toxicity Determination, compares EC
50Observation and theoretical value, can prove.
The complex composition of 2-cyano-3-amino-3-phenylancryic acetate of the present invention and S-Ethyl ethylthio sulfonate can be used for preventing and treating the strawberry verticillium wilt after making agricultural chemicals.By the strawberry that suffers from the strawberry verticillium wilt is used the agricultural chemicals root irrigation when the field planting, the statistics preventive effect proves that the agricultural chemicals of this complex composition preparation has remarkable control efficiency to the strawberry verticillium wilt.
The complex composition of 2-cyano-3-amino-3-phenylancryic acetate of the present invention and S-Ethyl ethylthio sulfonate can be used for preventing and treating bakanae disease of rice after making agricultural chemicals.By the rice seed soaking to the trouble bakanae disease, the vernalization sowing, add up preventive effect tillering stage before the nursery period transplanting and after transplanting, and proves that the agricultural chemicals of this complex composition preparation has remarkable control efficiency to bakanae disease of rice.
The complex composition of 2-cyano-3-amino-3-phenylancryic acetate of the present invention and S-Ethyl ethylthio sulfonate can be used for preventing and treating wheat scab after making agricultural chemicals.By complex composition of the present invention is mixed with agricultural chemicals, be sprayed onto field and investigation statistics in the dilution of wheat heading flowering period, prove that the agricultural chemicals of this complex composition preparation has remarkable control efficiency to wheat scab.
Beneficial effect: the complex composition of 2-cyano-3-amino-3-phenylancryic acetate of the present invention and S-Ethyl ethylthio sulfonate can be used for effectively preventing and treating strawberry verticillium wilt, bakanae disease of rice and wheat scab as the active ingredient of agricultural chemicals.With respect to independent use S-Ethyl ethylthio sulfonate, the agricultural chemicals preventive effect effect that complex composition of the present invention is made is remarkable, and avoids using missible oil; With respect to independent use 2-cyano-3-amino-3-phenylancryic acetate, the agricultural chemicals that the present invention makes still can be realized the preventive effect close with 25% 2-cyano-3-amino-3-phenylancryic acetate suspending agent, and the active ingredient S-Ethyl ethylthio sulfonate has reduced production cost widely.At present the former medicine cost of 2-cyano-3-amino-3-phenylancryic acetate is about 200,000 yuan/ton, and about 50,000 yuan/ton of the former medicine cost of S-Ethyl ethylthio sulfonate, 80,000 yuan/ton of 25% 2-cyano-3-amino-3-phenylancryic acetate suspending agent preparation market prices, 50,000 yuan/ton of 80% S-Ethyl ethylthio sulfonate missible oil market prices.
The present invention can effectively overcome the defective that contains a large amount of organic solvents in the missible oil by utilizing the formulations of pesticide of wetting powder and suspending agent.On the other hand, a kind of medicament of long-term use makes plant develop immunity to drugs easily and can not reach therapeutic purposes, adopts composite bactericidal composition can obviously improve control and result for the treatment of, has reduced the usage amount of agricultural chemicals, reduce cost, become the important means of the various diseases of integrated control.
Embodiment
Be further detailed below in conjunction with the present invention of embodiment.
Embodiment 1
The complex composition of 2-cyano-3-amino-3-phenylancryic acetate and S-Ethyl ethylthio sulfonate is made up of 2-cyano-3-amino-3-phenylancryic acetate and S-Ethyl ethylthio sulfonate, and wherein, the mass ratio of 2-cyano-3-amino-3-phenylancryic acetate and S-Ethyl ethylthio sulfonate is 1～36:6, and its preferred version is 1～4:2, and its optimal case is 1:1.
Embodiment 2
The complex composition of 2-cyano-3-amino-3-phenylancryic acetate of the present invention and S-Ethyl ethylthio sulfonate is mixed with the formulation of wetting powder and suspending agent.
During the preparation wetting powder, by add auxiliary agent and filler in complex composition of the present invention, after the mixing, making ultra-fine wettable powder by airslide disintegrating mill can obtain.Comprise 2-cyano-3-amino-3-phenylancryic acetate 5%～30% by mass percentage, S-Ethyl ethylthio sulfonate 5%～30%, Ricinate 8%～20%, all the other are filler, comprise white carbon 4%～10% in the described filler.
During the preparation suspending agent, complex composition of the present invention must be added solvent or cosolvent, emulsifier, be dissolved into even oil phase, again water, antifreeze, thickener, defoamer are mixed and be made into even water, under high-speed stirred and shearing force effect, water liquid is joined in the oil phase liquid, grind twice through sand mill, namely obtain the suspending agent of 2-cyano-3-amino-3-phenylancryic acetate S-Ethyl ethylthio sulfonate.More than the suspending agent of Huo Deing is ripe 2-cyano-3-amino-3-phenylancryic acetate S-Ethyl ethylthio sulfonate Pesticidal products, after packing, can effectively store, and plug and play, very easy to use.And the control efficiency of this suspending agent is better than wetting powder.
Embodiment 3
20g 2-cyano-3-amino-3-phenylancryic acetate, 20g S-Ethyl ethylthio sulfonate, 6g lauryl sodium sulfate, 8g sodium lignin sulfonate, 5g Nekal BX, diatomite are supplied 100g.Make 40% 2-cyano-3-amino-3-phenylancryic acetate S-Ethyl ethylthio sulfonate wetting powder.
Embodiment 4
10g 2-cyano-3-amino-3-phenylancryic acetate, 20g S-Ethyl ethylthio sulfonate, 7g ethoxylated dodecyl alcohol, 10g calcium lignosulfonate, 5g Nekal BX, kaolin are supplied 100g.Make 30% alkene bacterium ester S-Ethyl ethylthio sulfonate wetting powder.
Embodiment 5
20g 2-cyano-3-amino-3-phenylancryic acetate, 10g S-Ethyl ethylthio sulfonate, 7g dodecyl sodium sulfate, 10g calcium lignosulfonate, 5g Nekal BX, kaolin are supplied 100g.Make 30% alkene bacterium ester S-Ethyl ethylthio sulfonate wetting powder.
Embodiment 6
20g 2-cyano-3-amino-3-phenylancryic acetate, 20g S-Ethyl ethylthio sulfonate, 7g phenyl phenol polyoxy ethyl ether phosphate, 6g polyoxyethylene nonylphenol ether, 3g vegetable oil, 3g N-methyl pyrrolidone, 5g ethylene glycol, 0.4g silicone compound, water are mended to 100g, emulsifier and water are mixed and made into water, the former medicine that will be dissolved in then in the solvent under agitation adds water, through fully stirring and high speed shear, and through after twice grinding of sand mill, make 40% 2-cyano-3-amino-3-phenylancryic acetate S-Ethyl ethylthio sulfonate suspending agent.
Embodiment 7
20g 2-cyano-3-amino-3-phenylancryic acetate, 10g S-Ethyl ethylthio sulfonate, 4g vegetable oil, 6gN-methyl pyrrolidone, 6g phenyl phenol polyoxy ethyl ether, 5g tri ethanol ammonium salt, 4g propane diols, 0.2g silicone oil, water are mended to 100g, emulsifier and water are mixed and made into water, the former medicine that will be dissolved in then in the solvent under agitation adds water, back high speed shear, and through twice grinding of sand mill, make 30% alkene bacterium ester S-Ethyl ethylthio sulfonate suspending agent.
Test example 1 2-cyano-3-amino-3-phenylancryic acetate S-Ethyl ethylthio sulfonate is to the Toxicity Determination of strawberry verticillium wilt
This test example is carried out the drug effect comparison of former medicine respectively with 2-cyano-3-amino-3-phenylancryic acetate S-Ethyl ethylthio sulfonate complex composition of the present invention with 2-cyano-3-amino-3-phenylancryic acetate and S-Ethyl ethylthio sulfonate, by the mensuration to strawberry verticillium wilt indoor virulence, prove synergistic effect of the present invention.
Table 1 2-cyano-3-amino-3-phenylancryic acetate S-Ethyl ethylthio sulfonate is to the Toxicity Determination of strawberry verticillium wilt
As shown in Table 1, the composite bactericidal composition of 2-cyano-3-amino-3-phenylancryic acetate S-Ethyl ethylthio sulfonate of the present invention has higher synergistic effect to strawberry jaundice bacterium, wherein 2-cyano-3-amino-3-phenylancryic acetate S-Ethyl ethylthio sulfonate proportioning is 2:1 and 1:1, and synergistic effect is obvious, and when 2-cyano-3-amino-3-phenylancryic acetate: synergistic effect is the most outstanding during S-Ethyl ethylthio sulfonate=1:1.
Test example 2 2-cyano-3-amino-3-phenylancryic acetate S-Ethyl ethylthio sulfonates are prevented and treated bakanae disease of rice
The present invention tests in rice seed soaking test on May 6th, 2012, kind is No. 7, military fortune round-grained rice, collect bakanae disease heavy the field seed, press the extension rate seed soaking vernalization sowing after 48 hours in the table 2, soak seed period average temperature at 24-28 ℃, the seedling of seedling raising method drought, the clear water seed soaking is contrast, investigate investigation result such as table 2 tillering stage respectively at before the nursery period transplanting and transplanting back:
Table 2 2-cyano-3-amino-3-phenylancryic acetate S-Ethyl ethylthio sulfonate is prevented and treated the bakanae disease of rice field control effectiveness test
As seen from Table 2, present composition seed soaking is handled all remarkable to the bakanae disease of rice control efficiency, is higher than the contrast medicament, and to seed sprouting and fertility safety, bad reaction is not found in the field, reduces the effective ingredient consumption, delays to produce with preventing pesticide resistance.Just the market price of 2-cyano-3-amino-3-phenylancryic acetate and S-Ethyl ethylthio sulfonate is calculated at present, and in this test example, embodiment 3, embodiment 4, embodiment 6, embodiment 7 save cost 30-40% with respect to 25% 2-cyano-3-amino-3-phenylancryic acetate suspending agent.
Test example 3 2-cyano-3-amino-3-phenylancryic acetate S-Ethyl ethylthio sulfonates are prevented and treated wheat scab
The present invention test is converted 50 kilograms in water by every mu of dosage and is carried out all even and fine sprayings, in wheat heading flowering period spray medicine, after the week again medication once, dispenser is 2 times altogether, 25 days investigation results see Table 3 after the dispenser:
Table 3 2-cyano-3-amino-3-phenylancryic acetate S-Ethyl ethylthio sulfonate is prevented and treated the wheat scab field control effectiveness test
As seen from Table 3, the present composition has good control efficiency to wheat scab, and preventive effect all is higher than the contrast medicament, in test dosage scope to crop safety.Just the market price of 2-cyano-3-amino-3-phenylancryic acetate and S-Ethyl ethylthio sulfonate is calculated at present, and in this test example, embodiment 3, embodiment 4, embodiment 6, embodiment 7 save cost 30-40% with respect to 25% 2-cyano-3-amino-3-phenylancryic acetate suspending agent.
Test example 4 2-cyano-3-amino-3-phenylancryic acetate S-Ethyl ethylthio sulfonates control strawberry verticillium wilt and fusarium wilt
The present invention's test is converted 1200 kilograms of the water yields by every mu of medication amount of formulation, 6000 strains of greenhouse strawberry mu field planting strawberry seedling, kind is red cheek, carry out in long-term continuous cropping booth verticillium wilt and the heavy field of fusarium wilt last one year of generation, when the strawberry field planting, carry out root irrigation, 200 milliliters of every strain perfusion liquid measures, dispenser is 1 time altogether, 30 days investigation field efficacies after the dispenser, control efficiency such as table 4:
Table 4 2-cyano-3-amino-3-phenylancryic acetate S-Ethyl ethylthio sulfonate control strawberry verticillium wilt and fusarium wilt field control effectiveness test
Found out that by table 4 the composite bactericidal composition of 2-cyano-3-amino-3-phenylancryic acetate S-Ethyl ethylthio sulfonate of the present invention has the better prevention effect to strawberry verticillium wilt and fusarium wilt, find that in test said composition is to strawberry safety.Just the market price of 2-cyano-3-amino-3-phenylancryic acetate and S-Ethyl ethylthio sulfonate is calculated at present, and in this test example, embodiment 3, embodiment 4, embodiment 6, embodiment 7 save cost 30-40% with respect to 25% 2-cyano-3-amino-3-phenylancryic acetate suspending agent.
In sum, the composite bactericidal composition that the 2-cyano-3-amino-3-phenylancryic acetate S-Ethyl ethylthio sulfonate is composite has a medicine and controls more, synergy is obvious, the preventive effect height, and little to crop safety, environmental pollution, compare with single agent, enlarged fungicidal spectrum, reduced dosage, provided cost savings, the present invention is matrix with water or kaolin etc., environmentally safe, cost is low.So R﹠D and promotion of the present invention has higher using value.
The above only is preferred embodiment of the present invention; be noted that for those skilled in the art; under the prerequisite that does not break away from the principle of the invention, can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.
Claims (8)
1. the complex composition of a 2-cyano-3-amino-3-phenylancryic acetate and S-Ethyl ethylthio sulfonate, it is characterized in that: said composition effective active composition is 2-cyano-3-amino-3-phenylancryic acetate and S-Ethyl ethylthio sulfonate, the mass ratio of 2-cyano-3-amino-3-phenylancryic acetate and S-Ethyl ethylthio sulfonate is 1～36:6.
2. the complex composition of a kind of 2-cyano-3-amino-3-phenylancryic acetate according to claim 1 and S-Ethyl ethylthio sulfonate, it is characterized in that: the mass ratio of described 2-cyano-3-amino-3-phenylancryic acetate and S-Ethyl ethylthio sulfonate is 1～4:2.
3. the complex composition of a kind of 2-cyano-3-amino-3-phenylancryic acetate according to claim 1 and S-Ethyl ethylthio sulfonate, it is characterized in that: the mass ratio of described 2-cyano-3-amino-3-phenylancryic acetate and S-Ethyl ethylthio sulfonate is 1～2:1.
According to claim 1 the complex composition of a kind of 2-cyano-3-amino-3-phenylancryic acetate and S-Ethyl ethylthio sulfonate for the preparation of the application on the agricultural chemicals of control strawberry verticillium wilt.
According to claim 1 the complex composition of a kind of 2-cyano-3-amino-3-phenylancryic acetate and S-Ethyl ethylthio sulfonate for the preparation of the application on the agricultural chemicals of preventing and treating bakanae disease of rice.
According to claim 1 the complex composition of a kind of 2-cyano-3-amino-3-phenylancryic acetate and S-Ethyl ethylthio sulfonate for the preparation of the application on the agricultural chemicals of preventing and treating wheat scab.
According in the claim 4～6 any one described for the preparation of the application on the agricultural chemicals, it is characterized in that: the formulation of this agricultural chemicals is wetting powder or suspending agent.
According in the claim 4～6 any one described for the preparation of the application on the agricultural chemicals, it is characterized in that: described complex composition accounts for 10～60% of agricultural chemicals gross weight by mass percentage.
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