CN102846808A - Traditional Chinese drug composition for treating foal scrotal hernia - Google Patents
Traditional Chinese drug composition for treating foal scrotal hernia Download PDFInfo
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Abstract
The present invention provides a traditional Chinese drug composition for treating foal scrotal hernia, wherein the traditional Chinese drug composition comprises the following raw herbs: szechwan chinaberry fruit, Chinese thorowax root, lychee seed, fennel, frankincense, incised notopterygium rhizome and root, and wild celery. According to the present invention, spleen and stomach warming, cold dispelling, qi benefiting and spleen yang promoting are adopted as treatment principles, a formula is reasonable, a preparation process is simple, and an application range is wide; the traditional Chinese drug composition of the present invention is prepared from the pure Chinese herbals, and has characteristics of wide sources, low cost, high cure rate, no drug residue, and no toxic and side-effect, wherein especially plant cell walls can be destroyed at a maximum after ultrafine grinding so as to solve disadvantages of high crude fiber content and difficultly-dissolved active ingredient of the traditional medicine powder, such that the traditional Chinese drug composition is easily absorbed by horses; the traditional Chinese drug composition has effects of significant releasing analgesia, body function regulation and effective foal scrotal hernia treatment; and compared with western medicine treatment, the treatment of the present invention has characteristics of shortened recovery period and no recurrence.
Description
Technical field
The present invention relates to the technology of pharmaceutical engineering field, relate in particular to a kind of Chinese medicine composition for the treatment of young coltfoal scrotum hernia.
Background technology
At present, young coltfoal scrotocele is because abdominal viscera emerges in the scrotum from the abdominal cavity together with peritoneum, and a kind of common true property colic take obvious intermittent stomachache as feature is sick.
Children coltfoal scrotocele claims again hernia, Hull Buddhist nun Asia.Primary disease has two kinds of congenital and posteriorities, is generally a side, rare both sides property.Congenitally cause for the inguinal canal internal ring is excessive, cross that ambassador's inguinal canal is extended to be caused the day after tomorrow by intra-abdominal pressure, such as jump, gallop, hind leg slips or the posture of excessively opening a business etc. all can cause.
Primary disease children coltfoal is multiple, Chang Weiyi side hernia, and the Ipsilateral scrotum is excessive sagging, and palpation has sound equipment, and auscultation has peristaltic sound.Local painless without heat, if closing property of secondary embedding scrotocele suffers from then that coltfoal is suffered from abdominal pain suddenly, skin nervous, the step sample is arrested by force, severity of symptoms then panhidrosis, fervescence, embedding closes section's tissue necrosis, prognosis mala.
At this moment, if only use western medicine, not only toxic and side effects is larger, and unsatisfactory curative effect.The Therapeutic Method of generally acknowledging at present is the annulus inguinalis externalis incision, but operative treatment not only brings very large human and material resources consumption, and very risky, and convalescent period is long.
Summary of the invention
Technical problem to be solved by this invention is, overcoming prior art provides a kind of effective reduction toxic and side effects, eliminates operation risk, effectively treats the Chinese medicine composition that convalescent period after young coltfoal scrotum hernia and the treatment is short, reduce the young coltfoal scrotum of the treatment hernia of the stress that young coltfoal brings because of pain.
In order to solve the problems of the technologies described above, the invention provides a kind of Chinese medicine composition for the treatment of young coltfoal scrotum hernia, described Chinese medicine composition comprises following raw medicinal material: Fructus Toosendan, Radix Bupleuri, Semen Litchi, Fructus Foeniculi, Olibanum, Rhizoma Et Radix Notopterygii and Radix Angelicae Pubescentis.
The ratio of weight and number of the various raw medicinal materials in the described Chinese medicine composition is preferably, 20～30 parts of 20～30 parts of Fructus Toosendans, 15～25 parts of Radix Bupleuri, 15～25 parts of Semen Litchis, 15～25 parts in Fructus Foeniculi, 7～15 parts of Olibanums, 7～15 parts of Rhizoma Et Radix Notopterygiis and Radix Angelicae Pubescentiss.
The ratio of weight and number of the various raw medicinal materials in the described Chinese medicine composition can also be 24～26 parts of, 24～26 parts of Fructus Toosendans, 19～21 parts of Radix Bupleuri, 19～21 parts of Semen Litchis, 19～21 parts in Fructus Foeniculi, 9～11 parts of Olibanums, 9～11 parts of Rhizoma Et Radix Notopterygiis and Radix Angelicae Pubescentiss.
The ratio of weight and number of the kind raw medicinal material in the described Chinese medicine composition also can be preferably, 25 parts of 25 parts of Fructus Toosendans, 20 parts of Radix Bupleuri, 20 parts of Semen Litchis, 20 parts in Fructus Foeniculi, 10 parts of Olibanums, 10 parts of Rhizoma Et Radix Notopterygiis and Radix Angelicae Pubescentiss.
Described Chinese medicine composition can further include Fructus Evodiae, and the ratio of weight and number of described Fructus Evodiae is 15～20 parts.Be preferably 18 parts.
Described Chinese medicine composition can further include the Radix Astragali, Rhizoma Cimicifugae, Radix Ginseng and the Rhizoma Atractylodis Macrocephalae, and ratio of weight and number is respectively Radix Astragali 15-20 part, 15～20 parts of Rhizoma Cimicifugaes, Radix Ginseng 8-15 part and Rhizoma Atractylodis Macrocephalae 10-15 part.Be preferably 12 parts of 16 parts of the Radixs Astragali, 16 parts of Rhizoma Cimicifugaes, 10 parts of Radix Ginsengs and the Rhizoma Atractylodis Macrocephalaes.
The present invention also provides above-mentioned any one to treat the preparation method of the Chinese medicine composition of young coltfoal scrotum hernia, and the preparation method of described Chinese medicine composition is,
Step 1: take by weighing various raw medicinal materials according to percentage by weight, mix, be ground into powder, granularity is the 20-200 order;
Step 2: add 90 ~ 110 parts yellow wine in the powder of step 1, mix homogeneously.
Wherein, the granularity in the described step 1 is preferably the 150-200 order.
The present invention provides again above-mentioned any one to treat the preparation method of the Chinese medicine composition of young coltfoal scrotum hernia, and the preparation method of described Chinese medicine composition may further comprise the steps,
The first step is mixed in proportion described component, is ground into powder;
Second step obtains powder with the first step and adds in the cold water and soaked 6 hours～12 hours, and with slow fire boiling, decocting time is 3 hours～5 hours, and decoction liquor is filtered, and obtains the first filtrate, and the quality of the water that adds is 2～4 times of the powder quality that obtains of the first step;
In the 3rd step, the filtering residue that second step filter is obtained adds in the cold water again, with slow fire boiling 2 hours～4 hours, filters and obtains the second filtrate, and the quality of the water that adds is 2～4 times of the powder quality that obtains of second step;
In the 4th step, the first filtrate and the 3rd that second step is obtained goes on foot the second filtrate mixing that obtains, and concentrating under reduced pressure is except anhydrating, and drying is ground into powder, and granularity is 20～200 orders;
In the 5th step, in the powder in the 4th step, add 90 ~ 110 parts yellow wine, mix homogeneously.
Wherein, the granularity in described the 5th step is preferably the 150-200 order.
Wherein, the unit of above-mentioned various raw medicinal materials " part " is preferably " g ", and the unit of yellow wine " part " is preferably " ml ".
Beneficial effect of the present invention: the present invention is take warming spleen and stomach for dispelling cold, benefiting qi and raising yang as the rule for the treatment of, reasonable recipe, and preparation technology is simple, and is applied widely.The present invention adopts pure Chinese medicinal herbs to make, wide material sources, cost are low, cure rate is high, the medicine noresidue, have no side effect, particularly destroy to greatest extent plant cell wall after the micronizing, solved the deficiency that traditional drugs powder crude fiber content is high, effective ingredient is difficult to stripping, be easier to horses and absorb.Have the analgesia of releiving significantly and regulate the effect of body function, effectively treat young coltfoal scrotum hernia, shorten the period of convalescence with western medicine phase specific energy, and do not recur.
The specific embodiment
The invention provides a kind of Chinese medicine composition for the treatment of young coltfoal scrotum hernia, described Chinese medicine composition comprises following raw medicinal material: Fructus Toosendan, Radix Bupleuri, Semen Litchi, Fructus Foeniculi, Olibanum, Rhizoma Et Radix Notopterygii and Radix Angelicae Pubescentis.
The ratio of weight and number of the various raw medicinal materials in the described Chinese medicine composition is preferably, 20～30 parts of 20～30 parts of Fructus Toosendans, 15～25 parts of Radix Bupleuri, 15～25 parts of Semen Litchis, 15～25 parts in Fructus Foeniculi, 7～15 parts of Olibanums, 7～15 parts of Rhizoma Et Radix Notopterygiis and Radix Angelicae Pubescentiss.
The ratio of weight and number of the various raw medicinal materials in the described Chinese medicine composition can also be 24～26 parts of, 24～26 parts of Fructus Toosendans, 19～21 parts of Radix Bupleuri, 19～21 parts of Semen Litchis, 19～21 parts in Fructus Foeniculi, 9～11 parts of Olibanums, 9～11 parts of Rhizoma Et Radix Notopterygiis and Radix Angelicae Pubescentiss.
The ratio of weight and number of the kind raw medicinal material in the described Chinese medicine composition also can be preferably, 25 parts of 25 parts of Fructus Toosendans, 20 parts of Radix Bupleuri, 20 parts of Semen Litchis, 20 parts in Fructus Foeniculi, 10 parts of Olibanums, 10 parts of Rhizoma Et Radix Notopterygiis and Radix Angelicae Pubescentiss.
Described Chinese medicine composition can further include Fructus Evodiae, and the ratio of weight and number of described Fructus Evodiae is 15～20 parts.Be preferably 18 parts.
Described Chinese medicine composition can further include the Radix Astragali, Rhizoma Cimicifugae, Radix Ginseng and the Rhizoma Atractylodis Macrocephalae, and ratio of weight and number is respectively Radix Astragali 15-20 part, 15～20 parts of Rhizoma Cimicifugaes, Radix Ginseng 8-15 part and Rhizoma Atractylodis Macrocephalae 10-15 part.Be preferably 12 parts of 16 parts of the Radixs Astragali, 16 parts of Rhizoma Cimicifugaes, 10 parts of Radix Ginsengs and the Rhizoma Atractylodis Macrocephalaes.
The present invention also provides above-mentioned any one to treat the preparation method of the Chinese medicine composition of young coltfoal scrotum hernia, and the preparation method of described Chinese medicine composition is,
Step 1: take by weighing various raw medicinal materials according to percentage by weight, mix, be ground into powder, granularity is the 20-200 order;
Step 2: add 90 ~ 110 parts yellow wine in the powder of step 1, mix homogeneously.
Granularity in the described step 1 is preferably the 150-200 order.
The present invention provides again above-mentioned any one to treat the preparation method of the Chinese medicine composition of young coltfoal scrotum hernia, and the preparation method of described Chinese medicine composition may further comprise the steps,
The first step is mixed in proportion described component, is ground into powder;
Second step obtains powder with the first step and adds in the cold water and soaked 6 hours～12 hours, and with slow fire boiling, decocting time is 3 hours～5 hours, and decoction liquor is filtered, and obtains the first filtrate, and the quality of the water that adds is 2～4 times of the powder quality that obtains of the first step;
In the 3rd step, the filtering residue that second step filter is obtained adds in the cold water again, with slow fire boiling 2 hours～4 hours, filters and obtains the second filtrate, and the quality of the water that adds is 2～4 times of the powder quality that obtains of second step;
In the 4th step, the first filtrate and the 3rd that second step is obtained goes on foot the second filtrate mixing that obtains, and concentrating under reduced pressure is except anhydrating, and drying is ground into powder, and granularity is 20～200 orders;
In the 5th step, in the powder in the 4th step, add 90 ~ 110 parts yellow wine, mix homogeneously.
Granularity in described the 5th step is preferably the 150-200 order.
The pharmacology of described each component is as follows:
Fructus Toosendan: claim again chinaberry reality, Fructus Toosendan, core Fructus Jujubae, Fructus Toosendan, chinaberry, the stone Fructus Evodiae, Fructus Toosendan tree, Fructus Toosendan reality etc.Cold in nature, bitter in the mouth; Slightly poisonous.Return liver, small intestinal, urinary bladder channel.The energy soothing liver-QI, promoting the circulation of QI to relieve pain, anthelmintic.Be used for the breast side of body, abdominal distention, colic, abdominal pain due to worm stagnation.
Radix Bupleuri: another name: Asia puecon recklessly, smoke Shennong's Herbal, mountain dish, eat grass " WU Pu Bencao ", faggot " product converge smart will ".Cold nature, bitter in the mouth, suffering; GUIXIN bag, liver, gallbladder, tri-jiao channel.Evacuation is brought down a fever, dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy.Be used for fever caused by exogenous pathogens, the diseases such as the internal organs prolapsus of collapse of QI.Cure mainly: cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, the uterus comes off, menoxenia.
Semen Litchi: this product is the dry mature seed of sapindaceous plant Fructus Litchi Litchi chinensis Sonn..Pluck mature fruit summer, remove peel and meat aril, clean, dry.Have another name called that litchi props up, red litchi, beautiful branch.Warm in nature, sweet in the mouth, little hardship.Enter liver, kidney channel.Promoting QI to circulate and dispersing the agglomeration of the pathogens, cold-dispelling pain-relieving.Be used for colic of cold type stomachache, painful and swollen testis.
Fructus Foeniculi: claim again Fructus Foeniculi, bosom perfume, fragrant silk dish.Acrid in the mouth, warm in nature.Enter kidney, bladder, stomach warp.Energy warming the liver kidney, stimulating appetite, the cold expelling of regulating the flow of vital energy has supporing yang road.Cure mainly: cold in middle-JIAO, loss of appetite, nausea and vomiting, abdominal part cold type of pain; Hernia pain, painful and swollen testis; Stagnation of QI in spleen and stomach, distension and fullness in the abdomen are had a pain etc.
Olibanum: smoked Lu Xiang, horse hair is fragrant, nipple is fragrant, the perfume (or spice) that collapses, it pool is fragrant, Moller is fragrant, many gals Luo Xiang etc.Acrid in the mouth, hardship, warm in nature.Enter the heart, liver, spleen channel.Invigorate blood circulation circulation of qi promoting, pain relieving, detumescence and promoting granulation.Be used for traumatic injury, the skin infection carbuncle, congestion blocks all diseases etc." not Lu ": it be swollen to treat the edema due to wind pathogen poison, removes bad odor.Treat the urticaria poison of itching.Supplement to the Herbal: treat deaf, the apoplexy locked mouth, married woman's vim and vigour can be sent out wine, manage air-cooledly, only large intestine is let out Bleach, treats all skin ulcers and makes internal diabetes.
Rhizoma Et Radix Notopterygii: claim that again Qiang is blue or green, protect the envoy of Qiang, recklessly king envoy, Qiang sliding, move back wind envoy, black powder.Acrid in the mouth, hardship; Warm in nature.Enter bladder, kidney channel.Loose exterior cold; Wind-damp dispelling; Sharp joint; Pain relieving.Main affection of exogenous wind-cold; It is lossless to have a headache; Mimeograph cold-damp numbness; The edema due to wind pathogen edema; Sore swollen toxin.Be used for impotence and seminal emission, enuresis frequent micturition, chills and pain of the waist and kness is suffered from a deficiency of the kidney and is done to breathe heavily Diarrhoea; The external curing vitiligo, alopecia areata.The cold expelling that induces sweat, expelling wind and dampness, pain relieving.
Radix Angelicae Pubescentis: have another name called recklessly king envoy, solely shake grass, solely cunning, Sempervivum tectorum, RADIX ANGELICAE PUBESCENTIS from Sichuan of China, meat Radix Angelicae Pubescentis, qualifications and record of service Qiu's Radix Angelicae Pubescentis, the east of Sichuan Radix Angelicae Pubescentis, fragrant Radix Angelicae Pubescentis, achievement Radix Angelicae Pubescentis, Radix Angelicae Dahuricae (Radix Heraclei Scabridi), mountain Radix Angelicae Dahuricae (Radix Heraclei Scabridi), beautiful work.Acrid in the mouth, hardship, slightly warm in nature.Return liver, kidney, urinary bladder channel.Expelling wind and dampness; Dispersing cold for relieving pain.Be used for anemofrigid-damp arthralgia; Lumbocrural pain; Few cloudy volt wind headache, the headache toothache.
Yellow wine: be field of medicaments, very important adjuvant or " extra conductant ingredient " in the field of Chinese medicines particularly.Help blood circulation, enhance metabolism, have blood-enriching face-nourishing, an effect of the cold relieving of invigorating blood circulation, dredge the meridian passage, effectively the cold resisting stimulation, preventing cold.
Fructus Evodiae: another name Koji, volt spicy, smelly lake, Fructus Evodiae, tea are peppery, lacquer spicy, smelly spicy tree, the deep and remote son of Zuo Lichun, rice spicy etc.Acrid in the mouth, hardship, hot in nature; Slightly poisonous.Return liver, spleen, stomach, kidney channel.Dispersing cold for relieving pain, stopping nausea and vomiting by lowering the adverse flow of QI, supporing yang antidiarrheal.Be used for headache due to JUE YIN disorder, colic of cold type stomachache, the disturbance of lower legs due to pathogenic cold and dampness, dysmenorrhea, abdominal pain during menstruation, abdominal distention, vomiting acid regurgitation, Diarrhoea, external treatment aphtha; Hypertension.
The Radix Astragali: latin name Astragali Radix, sweet in the mouth, warm in nature, enter spleen, lung meridian, tonification spleen soil is arranged, elevate a turnable ladder yang-energy, strengthening superficial resistance to stop perspiration, the effect of holder skin ulcer granulation promoting cures mainly the weak anorexia and loose stool due to the deficiency of both the splenic and pulmonary QI, shortness of breath and palpitation, the visceroptosis of sinking of QI of middle-JIAO, the metrorrhagia of QI failing to control blood is had blood in stool, the chronic diarrhea proctoptosis; The spontaneous sweating of exterior deficiency, the cards such as insufficiency of vital energy and blood.The Radix Astragali strengthens the heart contraction ability, can improve the blood circulation of whole body, can coronary artery dilator, kidney blood vessel and Rhizoma Bistortae peripheral vessel, make cutaneous circulation vigorous; Can improve the nonspecific immunity power of body, the effect that protects the liver with blood sugar lowering is arranged, staphylococcus, blood dissolubility streptococcus, Diplococcus pneumoniae, dysentery bacterium etc. are had inhibitory action, but Radix Astragali appreciable impact splenocyte Information Conduction is realized immunoregulation effect.
Rhizoma Cimicifugae: have another name called big cattle card holder, Radix Longan, hole root of the tooth.Acrid in the mouth, little sweet, cold nature.Return lung, spleen, stomach, large intestine channel.Deliver rash, heat-clearing and toxic substances removing, elevate a turnable ladder yang-energy.Be used for headache due to pathogenic wind-heat, toothache, aphtha, laryngopharynx swelling and pain, measles without adequate eruption, YANG toxin syndrome is sent out speckle; Proctoptosis, uterine prolapse.
Radix Ginseng: SHANSHEN, Park Ginseng, people's rank, Coprinus atramentarius (Bull.) Fr. (Coprinus sterquilinus Fr.), wooden club, Rhizoma Panacis Japonici, SHENCAO, Sphallerocarpus gracilis, Herba Wedeliae Wallichii, Herba Stellariae Saxatilis, hundred chi pestles, extra large fat, the beautiful door screen of golden well, Radix Ginseng etc.Sweet in the mouth, little hardship, slightly warm in nature.Return spleen, lung, the heart, kidney channel.Strongly invigorating primordial QI, multiple arteries and veins takes off admittedly, and invigorating the spleen to benefit the lung promotes the production of body fluid and nourishes blood, the Fructus Alpiniae Oxyphyllae of calming the nerves.Be used for weak body and prostration, the cold extremities faint pulse, insufficiency of the spleen lack of appetite, the deficiency of the lung is breathed with cough, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, deficiency of qi and blood, prolonged illness is empty wins, the palpitation with fear insomnia, sexual impotence official is cold.Cure mainly: impairment caused by overstrain is deficient, lack of appetite, asthenia, regurgitation are told food, stool lingering diarrhea, empty cough with asthma are short, spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness and headache, sexual impotence, frequent micturition, quench one's thirst, woman uterine bleeding, children's's intermittent infantile convulsion and prolonged deficiency be multiple, the disease of all qi-blood-body fluid deficiencies.
The Rhizoma Atractylodis Macrocephalae: bitter in the mouth, sweet, warm in nature.Return spleen, stomach warp.Invigorating the spleen and benefiting QI, the dampness diuretic, hidroschesis, antiabortive.Be used for insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, the cards such as frequent fetal movement; The Rhizoma Atractylodis Macrocephalae have adjust gastrointestinal motility function, antiulcer, protect the liver, the effects such as enhancing human body immunity function, anti-stress, enhancing hemopoietic function; Its dampness diuretic effect is relevant with diuresis; And antiabortive effect is relevant with the effect of inhibition uterine contraction.The Rhizoma Atractylodis Macrocephalae also has the effects such as antioxidation, slow down aging, blood sugar lowering, anticoagulation, antitumor.
Below adopt embodiment to describe embodiments of the present invention in detail, how the application technology means solve technical problem to the present invention whereby, and the implementation procedure of reaching technique effect can fully understand and implements according to this.
Embodiment 1:
Fructus Toosendan 25g, Radix Bupleuri 20g, Semen Litchi 20g, Fructus Foeniculi 20g, Olibanum 10g, Rhizoma Et Radix Notopterygii 10g and Radix Angelicae Pubescentis 25g.Mix, be ground into powder, granularity is 200 orders; In powder, add the 100ml yellow wine, mix homogeneously.During use, gavage.
Embodiment 2:
Fructus Toosendan 24g, Radix Bupleuri 19g, Semen Litchi 19g, Fructus Foeniculi 20g, Olibanum 9g, Rhizoma Et Radix Notopterygii 9g, Radix Angelicae Pubescentis 24g and Fructus Evodiae 18g.Mix, be ground into powder, granularity is 180 orders; In powder, add the 90ml yellow wine, mix homogeneously.During use, gavage.
Embodiment 3:
Fructus Toosendan 26g, Radix Bupleuri 21g, Semen Litchi 21g, Fructus Foeniculi 19g, Olibanum 10g, Rhizoma Et Radix Notopterygii 11g, Radix Angelicae Pubescentis 26g, Radix Astragali 16g, Rhizoma Cimicifugae 16g, Radix Ginseng 10g and Rhizoma Atractylodis Macrocephalae 12g.Preparation method may further comprise the steps:
The first step is mixed in proportion various raw medicinal materials, is ground into powder;
Second step obtains powder with the first step and adds in the cold water and soaked 10 hours, and with slow fire boiling, decocting time is 4 hours, and decoction liquor is filtered, and obtains the first filtrate, and the quality of the water that adds is 4 times of the powder quality that obtains of the first step;
In the 3rd step, the filtering residue that second step filter is obtained adds in the cold water again, with slow fire boiling 3 hours, filters and obtains the second filtrate, and the quality of the water that adds is 3 times of the powder quality that obtains of second step;
In the 4th step, the first filtrate and the 3rd that second step is obtained goes on foot the second filtrate mixing that obtains, and concentrating under reduced pressure is except anhydrating, and drying is ground into powder, and granularity is 150 orders;
In the 5th step, add the yellow wine of 100ml, mix homogeneously in the powder in the 4th step.
During use, gavage.
Embodiment 4:
Fructus Toosendan 26g, Radix Bupleuri 19g, Semen Litchi 20g, Fructus Foeniculi 21g, Olibanum 11g, Rhizoma Et Radix Notopterygii 10g, Radix Angelicae Pubescentis 25g, Fructus Evodiae 20g, Radix Astragali 18g, Rhizoma Cimicifugae 20g, Radix Ginseng 12g and Rhizoma Atractylodis Macrocephalae 10g.Preparation method may further comprise the steps:
The first step is mixed in proportion various raw medicinal materials, is ground into powder;
Second step obtains powder with the first step and adds in the cold water and soaked 8 hours, and with slow fire boiling, decocting time is 5 hours, and decoction liquor is filtered, and obtains the first filtrate, and the quality of the water that adds is 3 times of the powder quality that obtains of the first step;
In the 3rd step, the filtering residue that second step filter is obtained adds in the cold water again, with slow fire boiling 4 hours, filters and obtains the second filtrate, and the quality of the water that adds is 4 times of the powder quality that obtains of second step;
In the 4th step, the first filtrate and the 3rd that second step is obtained goes on foot the second filtrate mixing that obtains, and concentrating under reduced pressure is except anhydrating, and drying is ground into powder, and granularity is 200 orders;
In the 5th step, add the yellow wine of 110ml, mix homogeneously in the powder in the 4th step.
During use, gavage.
Acute toxicity test:
Use 120 of NIH mices, the SPF level, male and female half and half, body weight 18～22g carries out acute toxicity testing.Mice is divided into three groups at random, be that (concentration is 6.28g crude drug/ml for the Chinese medicine composition of matched group, the administration embodiment of the invention 1, maximum concentration) (concentration is 6.28g crude drug/ml for administration group 1 and the administration embodiment of the invention 4, the administration group 2 of Chinese medicine composition maximum concentration), fasting is 12 hours before the experiment.Administration group 1 and administration group 2 are dissolved in the water Chinese medicinal powder of embodiments of the invention 1 and embodiment 4 preparations to mouse stomach respectively, the gavage volume is that 5ml/kg (is that single-dose dosage is 31.4g crude drug/kg), matched group gives the equivalent normal saline, administration in 1 day 2 times, delivery time 6 hours, Continuous Observation is 14 days after the administration, and toxic reaction and the death toll of record mice.Experimental result shows: with matched group relatively, mice has no notable difference after the administration, experiment Continuous Observation 14 days, the mice overall health of patients, ingest, drinking-water, body weight gain is all normal.Therefore Chinese medicine acute toxicity of the present invention is low, clinical drug safety.
Clinical trial:
Chinese medicine composition avirulence of the present invention, easy to use, can directly gavage or add in the feedstuff and use.During application, Chinese medicine composition of the present invention directly can be gavaged by per kilogram of body weight 0.4g crude drug, perhaps mix and feed young coltfoal in the feedstuff, and statistical data shows, can fully recover in general the continuous 4-20 of taking days, and treatment time is short, clinical cure rate reaches 95%, and cure rate is high.
Model case 1
Hebei province's veterinary station Mongolian horse
This veterinary station is successively accepted the young coltfoal that 11 examples suffer from groin scrotum hernia for medical treatment, and trouble coltfoal left side scrotum is excessive sagging, and the palpation softness is with sound equipment, in the auscultation scrotum peristaltic sound is arranged, will suffer from coltfoal and lie on the back, deviate from intestinal tube then from being advanced into the abdominal cavity, local without thermal response, intermittent stomachache is arranged, again and again wag the tail etc.Use the Chinese medicine composition of the embodiment of the invention 1, press the dosage in the prescription, add yellow wine 100ml after being ground into powder, gavage that (dosage is 0.4g crude drug/kg), twice on the one; Wherein 4, observe after serveing on respectively 4-6 days, suffer from coltfoal and all fully recover; Wherein 5, take continuously respectively after 7-10 days and observe, suffer from coltfoal and all fully recover; Wherein 2, take continuously respectively and observed afterwards in 12 days and 15 days, suffer from coltfoal and all fully recover; Every example all had no recurrence in 2 months with examining.
Model case 2
Hebei province county peasant household Mongolian horse
This colt was born rear three days, suddenly suffer from abdominal pain, the right side scrotum is excessive, and skin of scrotum is tight, and with swelling, a cold, the Ipsilateral hind leg outwards stretched when fortune went on foot, and the step sample is arrested by force, and inspection right side scrotum is excessive, in the auscultation scrotum peristaltic sound is arranged, can touch annulus inguinalis externalis by the outside, forelimb is planed the ground, and intermittent stomachache is arranged.Use the dosage in the Chinese medicine composition prescription of the embodiment of the invention 4, add yellow wine 110ml after being prepared into powder, gavage that (dosage is 0.4g crude drug/kg).One day twice, serve on five days after, be completely recovered, with examine 2 months not the recurrence.
This intellectual property of primary enforcement that all are above-mentioned is not set restriction this new product of other forms of enforcement and/or new method.Those skilled in the art will utilize this important information, and foregoing is revised, to realize similar implementation status.But all modifications or transformation belong to the right of reservation based on new product of the present invention.
The above only is preferred embodiment of the present invention, is not to be the restriction of the present invention being made other form, and any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the equivalent embodiment of equivalent variations.But every technical solution of the present invention content that do not break away to any simple modification, equivalent variations and remodeling that above embodiment does, still belongs to the protection domain of technical solution of the present invention according to technical spirit of the present invention.
Claims (10)
1. a Chinese medicine composition for the treatment of young coltfoal scrotum hernia is characterized in that described Chinese medicine composition comprises following raw medicinal material: Fructus Toosendan, Radix Bupleuri, Semen Litchi, Fructus Foeniculi, Olibanum, Rhizoma Et Radix Notopterygii and Radix Angelicae Pubescentis.
2. the Chinese medicine composition of the young coltfoal scrotum for the treatment of as claimed in claim 1 hernia, it is characterized in that: the ratio of weight and number of the various raw medicinal materials in the described Chinese medicine composition is, 20～30 parts of 20～30 parts of Fructus Toosendans, 15～25 parts of Radix Bupleuri, 15～25 parts of Semen Litchis, 15～25 parts in Fructus Foeniculi, 7～15 parts of Olibanums, 7～15 parts of Rhizoma Et Radix Notopterygiis and Radix Angelicae Pubescentiss.
3. the Chinese medicine composition of the young coltfoal scrotum for the treatment of as claimed in claim 1 or 2 hernia, it is characterized in that: the ratio of weight and number of the various raw medicinal materials in the described Chinese medicine composition is, 24～26 parts of 24～26 parts of Fructus Toosendans, 19～21 parts of Radix Bupleuri, 19～21 parts of Semen Litchis, 19～21 parts in Fructus Foeniculi, 9～11 parts of Olibanums, 9～11 parts of Rhizoma Et Radix Notopterygiis and Radix Angelicae Pubescentiss.
4. such as the Chinese medicine composition of the young coltfoal scrotum of the described treatment of claims 1 to 3 hernia, it is characterized in that: the ratio of weight and number of the kind raw medicinal material in the described Chinese medicine composition is, 25 parts of 25 parts of Fructus Toosendans, 20 parts of Radix Bupleuri, 20 parts of Semen Litchis, 20 parts in Fructus Foeniculi, 10 parts of Olibanums, 10 parts of Rhizoma Et Radix Notopterygiis and Radix Angelicae Pubescentiss.
5. such as the Chinese medicine composition of the young coltfoal scrotum of the described treatment of claim 1 to 4 hernia, it is characterized in that: described Chinese medicine composition also further comprises Fructus Evodiae, and the ratio of weight and number of described Fructus Evodiae is 15～20 parts.
6. such as the Chinese medicine composition of the young coltfoal scrotum of the described treatment of claim 1 to 5 hernia, it is characterized in that: described Chinese medicine composition also further comprises the Radix Astragali, Rhizoma Cimicifugae, Radix Ginseng and the Rhizoma Atractylodis Macrocephalae, and ratio of weight and number is respectively Radix Astragali 15-20 part, 15～20 parts of Rhizoma Cimicifugaes, Radix Ginseng 8-15 part and Rhizoma Atractylodis Macrocephalae 10-15 part.
7. such as the Chinese medicine composition of the young coltfoal scrotum of the described treatment of claim 1 to 6 hernia, it is characterized in that: the preparation method of described Chinese medicine composition is,
Step 1: take by weighing various raw medicinal materials according to percentage by weight, mix, be ground into powder, granularity is the 20-200 order;
Step 2: add 90 ~ 110 parts yellow wine in the powder of step 1, mix homogeneously.
8. the Chinese medicine composition of the young coltfoal scrotum for the treatment of as claimed in claim 7 hernia, it is characterized in that: the granularity in the described step 1 is the 150-200 order.
9. such as the Chinese medicine composition of the young coltfoal scrotum of the described treatment of claim 1 to 6 hernia, it is characterized in that:
The preparation method of described Chinese medicine composition may further comprise the steps,
The first step is mixed in proportion described component, is ground into powder;
Second step obtains powder with the first step and adds in the cold water and soaked 6 hours～12 hours, and with slow fire boiling, decocting time is 3 hours～5 hours, and decoction liquor is filtered, and obtains the first filtrate, and the quality of the water that adds is 2～4 times of the powder quality that obtains of the first step;
In the 3rd step, the filtering residue that second step filter is obtained adds in the cold water again, with slow fire boiling 2 hours～4 hours, filters and obtains the second filtrate, and the quality of the water that adds is 2～4 times of the powder quality that obtains of second step;
In the 4th step, the first filtrate and the 3rd that second step is obtained goes on foot the second filtrate mixing that obtains, and concentrating under reduced pressure is except anhydrating, and drying is ground into powder, and granularity is 20～200 orders;
In the 5th step, in the powder in the 4th step, add 90 ~ 110 parts yellow wine, mix homogeneously.
10. the Chinese medicine composition of the young coltfoal scrotum for the treatment of as claimed in claim 9 hernia is characterized in that: the granularity in described the 5th step is the 150-200 order.
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Granted publication date: 20131225 |
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| CF01 | Termination of patent right due to non-payment of annual fee |