CN102754738A - Nano vitamin D3 for producing feed and preparation method thereof - Google Patents
Nano vitamin D3 for producing feed and preparation method thereof Download PDFInfo
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- CN102754738A CN102754738A CN2012102649578A CN201210264957A CN102754738A CN 102754738 A CN102754738 A CN 102754738A CN 2012102649578 A CN2012102649578 A CN 2012102649578A CN 201210264957 A CN201210264957 A CN 201210264957A CN 102754738 A CN102754738 A CN 102754738A
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Abstract
The invention provides a nano vitamin D3 for producing feed and a preparation method thereof. Every 1kg of nano vitamin D3 powder comprises the following nutrients and the contents of the nutrients: 3500,000 IU (International Unit)/g and 900g of carrier. According to the preparation method of the nano vitamin D3, the grain size of vitamin is controlled to be within 100nm and nano vitamin of a new preparation form having nano effect is formed. Compared with the common vitamin D3, the nano vitamin provided by the invention has remarkably improved superior physical properties such as dissolubility, absorptivity, trophism and physiological and biochemical process in an organism.
Description
Technical field
The invention belongs to field of feed, relate to a kind of nanometer vitamin its preparation method, be specifically related to a kind of nanometer vitamin D that is used for Feed Manufacturing
3Its preparation method.
Background technology
Vitamin D is a kind of steroid derivatives, has anti-rachitic effect, so be called antirachitic vitamin.The vitamin D kind is a lot, and wherein more important have a vitamin D
2(ergocalciferol) and vitamin D
3(courage solidifies alcohol), the two structure is quite similar, is soluble in organic solvents such as fat, oil and ether, is not soluted in water, so be called liposoluble vitamin.The vitamin Ds that use in the Feed Manufacturing more
3Be the livestock and poultry vitamin D Can.Vitamin D particularly more is prone to be destroyed when heating, so should be stored in the lucifuge environment to air and photaesthesia.
Vitamin D
3Biological function more extensive: regulate alcium and phosphor metabolization, improve the absorption of body calcium, phosphorus; Promote bone growth; Can suppress multiple histocyte propagation, differentiation and change cell biological function; Bring into play immunological regulation, improve glycometabolism; Prevent that amino acid from passing through the kidney loss.Vitamin D deficiency usually is because the following aspects: 1. by the feed insufficiency of intake; 2. solar radiation is not enough; 3. intestinal absorption is bad; 4. growth of animals or poultry is very fast, and required vitamin D is many.
On the existing feedstuff market, the plain edition vitamin D
3, specification (500,000 IU/g) is dissolved the water-based extreme difference, and for satisfying the vitamin needs of livestock and poultry, therefore use amount is bigger in feed, causes certain wasting of resources.Simultaneously, the employed monomer of drinking water type feed product " the water soluble vitamin D of part
3" specification (500,000 IU/g), molten water-based is good slightly, but utilizes rate variance.And the nano vitamin D
3Can effectively improve this situation.
Summary of the invention
The objective of the invention is to overcome the above-mentioned deficiency of existing in prior technology, a kind of nanometer vitamin D that is used for Feed Manufacturing is provided
3Its preparation method.The nanometer vitamin D that the present invention relates to
3Be meant through certain processing method, the size of vitamin particulate is controlled in the 100nm, form novel form nanometer vitamin D with nanometer effect
3With common vitamin D
3Physical characteristic compare, nanometer vitamin all can be significantly improved in dissolubility, absorptivity, trophism and the superiority that in body, shown in the physiological and biochemical procedure.
Its technical scheme is:
A kind of nanometer vitamin D that is used for Feed Manufacturing
3, per 1 kilogram of nanometer vitamin D
3Nutritional labeling and content are in the powder: vitamin D
350 million international units (IU)/gram (g), surplus is a carrier, content is 900 grams.
Said carrier is the oligoisomaltose powder.
A kind of nanometer vitamin D that is used for Feed Manufacturing
3The preparation method, it is characterized in that, may further comprise the steps:
1) vitamin D
3Nanometer emulsified: by the accurate weighing 100g VD3 oil of prescription, raw material specification is 5,000,000 IU/g, adds 200ml emulsifying agent, stabilizing agent EDTA 10g, under 65 ℃, adopts ultrasonic wave, carries out emulsification earlier, and adding distil water 200ml stirs to clarify bright, forms vitamin D
3Nano-emulsion;
2) by the accurate weighing oligoisomaltose powder 900g of prescription, carry out ultramicro grinding, particle diameter mixes with the nano-emulsion of step 1) gained less than 5 μ m;
3) with wet mixture under 65 ℃, dry and promptly got the nanometer vitamin D in 4 hours
3, granulate or be made as powder and use.
Further preferred, emulsifying agent is Tween 80 and sorbester p18 in the step 1).
Further, Tween 80: sorbester p18=2: 1.
Beneficial effect of the present invention:
Compared with prior art, technical scheme of the present invention has the following advantages:
The nanometer vitamin D that is used for livestock and poultry cultivation of the present invention
3Feed Manufacturing be can be widely used in, spice type feed product and water-soluble feed product comprised, effectively vitamin D Can
3, obviously improve bioavailability, reduce the feed excess and add the plain edition vitamin D
3The wasting of resources that raw material monomer causes etc.
The specific embodiment
Below in conjunction with specific embodiment technical scheme of the present invention is explained further details.
Embodiment 1 the present invention is a kind of nanometer vitamin D that is used for Feed Manufacturing
3, per 1 kilogram of nanometer vitamin D
3Nutrient composition content is in the powder: vitamin D
350 million international units (IU)/gram (g), surplus are carrier oligoisomaltose powder, and content is 900 grams.
Implementation procedure of the present invention divided for three steps:
1) vitamin D
3Nanometer emulsified process; Earlier by the accurate weighing 100g VD3 oil of prescription (raw material specification: 5,000,000 IU/g), add the 200ml emulsifying agent (Tween 80: sapn, 60=2: 1), stabilizing agent EDTA 10g, under 65 ℃; Adopt ultrasonic wave; Carry out emulsification, adding distil water 200ml stirs to clarify bright, forms vitamin D
3Nano-emulsion;
2) by the accurate weighing oligoisomaltose powder 900g of prescription, carry out ultramicro grinding (particle diameter is less than 5 μ m), mix with above-mentioned nano-emulsion the back;
3) with wet mixture under 65 ℃, dry and promptly got the nanometer vitamin D in 4 hours
3, can granulate or be made as powder as required and use.
Emulsifying agent of the present invention, safety, nonhazardous.
Carrier used in the present invention is the oligoisomaltose powder.
Nanometer vitamin D of the present invention
3Interpolation use:
Adding method for using is: when being used to process spice type feed product, use vitamin D by prescription
3, 500,000 IU/g conversion, and mix.When being used to process the drinking water type feed product, use vitamin D by prescription
3, 500,000 IU/g conversion, and mix.
Embodiment 2
The nanometer vitamin D
3, usual vitamin D
3And water soluble vitamin D
3Dissolve the water contrast test.
Result of the test is seen table 1:
Table 1
From table 1, can find out this nanometer vitamin D
3, water-soluble the best, thus in the water-soluble medium in the livestock and poultry body, can be thorough, thus effectively satisfy the needs of body to it.
The above; Be merely the preferable specific embodiment of the present invention; Protection scope of the present invention is not limited thereto; Any technical staff who is familiar with the present technique field is in the technical scope that the present invention discloses, and the simple change of the technical scheme that obtains or equivalence replacement all fall in protection scope of the present invention with may be obvious that.
Claims (5)
1. nanometer vitamin D that is used for Feed Manufacturing
3, it is characterized in that per 1 kilogram of nanometer vitamin D
3Nutritional labeling and content are in the powder: vitamin D
350 million international units (IU)/gram (g), surplus is a carrier, content is 900 grams.
2. the nanometer vitamin D that is used for Feed Manufacturing according to claim 1
3, it is characterized in that said carrier is the oligoisomaltose powder.
3. described nanometer vitamin D that is used for Feed Manufacturing of claim 1
3The preparation method, it is characterized in that, may further comprise the steps:
1) vitamin D
3Nanometer emulsified: by the accurate weighing 100g VD3 oil of prescription, raw material specification is 5,000,000 IU/g, adds 200ml emulsifying agent, stabilizing agent EDTA 10g, under 65 ℃, adopts ultrasonic wave, carries out emulsification earlier, and adding distil water 200ml stirs to clarify bright, forms vitamin D
3Nano-emulsion;
2) by the accurate weighing oligoisomaltose powder 900g of prescription, carry out ultramicro grinding, particle diameter mixes with the nano-emulsion of step 1) gained less than 5 μ m;
3) with wet mixture under 65 ℃, dry and promptly got the nanometer vitamin D in 4 hours
3, granulate or be made as powder and use.
4. the nanometer vitamin D that is used for Feed Manufacturing according to claim 3
3The preparation method, it is characterized in that emulsifying agent is Tween 80 and sorbester p18 in the step 1).
5. the nanometer vitamin D that is used for Feed Manufacturing according to claim 4
3The preparation method, it is characterized in that Tween 80: sorbester p18=2: 1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012102649578A CN102754738A (en) | 2012-07-27 | 2012-07-27 | Nano vitamin D3 for producing feed and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012102649578A CN102754738A (en) | 2012-07-27 | 2012-07-27 | Nano vitamin D3 for producing feed and preparation method thereof |
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|---|---|
| CN102754738A true CN102754738A (en) | 2012-10-31 |
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| CN2012102649578A Pending CN102754738A (en) | 2012-07-27 | 2012-07-27 | Nano vitamin D3 for producing feed and preparation method thereof |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103520102A (en) * | 2013-10-14 | 2014-01-22 | 陕西科技大学 | Vitamin D nano-emulsion and preparation method thereof |
| CN103636942A (en) * | 2013-11-11 | 2014-03-19 | 陕西金冠牧业有限公司 | Nanometer nutrient compound for broiler chicken farming |
| CN104686812A (en) * | 2014-11-18 | 2015-06-10 | 陕西金冠牧业有限公司 | Preparation method of nano vitamin D3 for coating of feed |
| CN105053561A (en) * | 2015-07-29 | 2015-11-18 | 山东迅达康生物科技有限公司 | Nano-level feed additive and preparation method thereof |
| CN105104759A (en) * | 2015-09-23 | 2015-12-02 | 陕西金冠牧业有限公司 | Preparation method of nano vitamin A used for feed production |
| CN112970946A (en) * | 2021-03-16 | 2021-06-18 | 陕西金冠牧业有限公司 | New generation of compound vitamin AD for feed3Preparation of E |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103520102A (en) * | 2013-10-14 | 2014-01-22 | 陕西科技大学 | Vitamin D nano-emulsion and preparation method thereof |
| CN103636942A (en) * | 2013-11-11 | 2014-03-19 | 陕西金冠牧业有限公司 | Nanometer nutrient compound for broiler chicken farming |
| CN103636942B (en) * | 2013-11-11 | 2015-10-28 | 陕西金冠牧业有限公司 | A kind of element of the nano nutrient for broiler breeding compound |
| CN104686812A (en) * | 2014-11-18 | 2015-06-10 | 陕西金冠牧业有限公司 | Preparation method of nano vitamin D3 for coating of feed |
| CN104686812B (en) * | 2014-11-18 | 2020-01-03 | 陕西金冠牧业有限公司 | Coated nano vitamin D for feed3Preparation method of (1) |
| CN105053561A (en) * | 2015-07-29 | 2015-11-18 | 山东迅达康生物科技有限公司 | Nano-level feed additive and preparation method thereof |
| CN105104759A (en) * | 2015-09-23 | 2015-12-02 | 陕西金冠牧业有限公司 | Preparation method of nano vitamin A used for feed production |
| CN112970946A (en) * | 2021-03-16 | 2021-06-18 | 陕西金冠牧业有限公司 | New generation of compound vitamin AD for feed3Preparation of E |
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