CN102727752A - Application of Wu Hu Dan capsules in preparing medicine used for treating gout - Google Patents
Application of Wu Hu Dan capsules in preparing medicine used for treating gout Download PDFInfo
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- CN102727752A CN102727752A CN2012102036155A CN201210203615A CN102727752A CN 102727752 A CN102727752 A CN 102727752A CN 2012102036155 A CN2012102036155 A CN 2012102036155A CN 201210203615 A CN201210203615 A CN 201210203615A CN 102727752 A CN102727752 A CN 102727752A
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- China
- Prior art keywords
- capsules
- gout
- application
- treating gout
- dan
- Prior art date
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Links
- 201000005569 Gout Diseases 0.000 title claims abstract description 21
- 239000002775 capsule Substances 0.000 title claims abstract description 18
- 239000003814 drug Substances 0.000 title claims abstract description 15
- 239000008280 blood Substances 0.000 abstract description 4
- 210000004369 blood Anatomy 0.000 abstract description 4
- 238000009825 accumulation Methods 0.000 abstract description 3
- 230000001684 chronic effect Effects 0.000 abstract description 3
- 241001250596 Pleione Species 0.000 abstract description 2
- 230000017531 blood circulation Effects 0.000 abstract description 2
- 230000006870 function Effects 0.000 abstract description 2
- 201000007094 prostatitis Diseases 0.000 abstract description 2
- JHGWQSGWUPCKNT-UHFFFAOYSA-N 2-tert-butyl-4-methyl-1,3,5-trinitrobenzene Chemical compound CC1=C([N+]([O-])=O)C=C([N+]([O-])=O)C(C(C)(C)C)=C1[N+]([O-])=O JHGWQSGWUPCKNT-UHFFFAOYSA-N 0.000 abstract 1
- 241000846171 Cremastra Species 0.000 abstract 1
- 241000865486 Knoxia Species 0.000 abstract 1
- 244000153955 Reynoutria sachalinensis Species 0.000 abstract 1
- 235000003202 Reynoutria sachalinensis Nutrition 0.000 abstract 1
- 240000003152 Rhus chinensis Species 0.000 abstract 1
- 235000014220 Rhus chinensis Nutrition 0.000 abstract 1
- 241000304195 Salvia miltiorrhiza Species 0.000 abstract 1
- 235000011135 Salvia miltiorrhiza Nutrition 0.000 abstract 1
- 230000003213 activating effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 8
- 201000001431 Hyperuricemia Diseases 0.000 description 5
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 238000003745 diagnosis Methods 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- IAKHMKGGTNLKSZ-INIZCTEOSA-N (S)-colchicine Chemical compound C1([C@@H](NC(C)=O)CC2)=CC(=O)C(OC)=CC=C1C1=C2C=C(OC)C(OC)=C1OC IAKHMKGGTNLKSZ-INIZCTEOSA-N 0.000 description 2
- 208000006820 Arthralgia Diseases 0.000 description 2
- 241000282414 Homo sapiens Species 0.000 description 2
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 241000521257 Hydrops Species 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 206010023215 Joint effusion Diseases 0.000 description 1
- 241000972155 Moschus Species 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- OFCNXPDARWKPPY-UHFFFAOYSA-N allopurinol Chemical compound OC1=NC=NC2=C1C=NN2 OFCNXPDARWKPPY-UHFFFAOYSA-N 0.000 description 1
- 229960003459 allopurinol Drugs 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 208000035850 clinical syndrome Diseases 0.000 description 1
- 229960001338 colchicine Drugs 0.000 description 1
- 238000011443 conventional therapy Methods 0.000 description 1
- 208000029078 coronary artery disease Diseases 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000000378 dietary effect Effects 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 201000001819 hydrarthrosis Diseases 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 210000000088 lip Anatomy 0.000 description 1
- 230000003908 liver function Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000002075 main ingredient Substances 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 description 1
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 208000037920 primary disease Diseases 0.000 description 1
- DBABZHXKTCFAPX-UHFFFAOYSA-N probenecid Chemical compound CCCN(CCC)S(=O)(=O)C1=CC=C(C(O)=O)C=C1 DBABZHXKTCFAPX-UHFFFAOYSA-N 0.000 description 1
- 229960003081 probenecid Drugs 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000004144 purine metabolism Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 208000037816 tissue injury Diseases 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 229940116269 uric acid Drugs 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses an application of Wu Hu Dan capsules in preparing a medicine used for treating gout. The main components of the capsules are giant knotweed rhizome, sargenrgloryvine, salvia miltiorrhiza, appendiculate cremastra pseudobulb or common pleione pseudobulb, knoxia root, Chinese nut-gall, and artificial musk. The capsules are orally taken, 2 capsules once, and three times a day. The capsules provide functions of heat clearing, dampness eliminating, blood circulation activating, and bind dissipating. The capsules can be used in treating chronic nonspecific prostatitis heat accumulation and blood stasis. The capsules can be used for treating gout.
Description
Technical field
The present invention relates to a kind of new purposes of Chinese patent medicine, relate in particular to the application of Five Tiger Pellet capsule in preparation treatment gout medicine.
Background technology
Along with the change of The development in society and economy, dietary structure and the prolongation of human longevity, the sickness rate of gout improves day by day, has become the person in middle and old age's of the world today commonly encountered diseases.The existence of gout also can cause the deterioration of coronary heart disease, diabetes, hypertension etc., and human beings'health has been constituted potential threat.Modern medicine does not still have the radical cure method to primary disease at present.
Gout is that long-term purine metabolism obstacle and urate excretion reduce, blood uric acid increases the one group of clinical syndrome that causes tissue injury, and hyperuricemia is the most important biochemical character of gout.At present; Conventional therapy for gout and hyperuricemia is main with Western medicine still; Usually select chemicalses such as colchicine, nonsteroidal antiinflammatory drug, probenecid, allopurinol for use, these medicines reach the purpose of alleviating or treating gout and hyperuricemia with different effect links, though curative effect is all right; But increasing clinical observation finds that they all have certain toxic and side effects, and is especially more serious to person in middle and old age and the unsound patient's of hepatic and renal function side effect.
Chinese medicine and ethnic drug have characteristics such as toxicity is little, treating both the principal and secondary aspects of a disease, can improve symptom in acute stage, can regulate function in chronic phase and catabasis again, play and make body negative and positive of qi and blood balance, reduce effects such as recurrence.Therefore seeking with the Chinese herbal medicine is that the medicine of the treatment gout of primary raw material has caused numerous scientific and technical personnel's close attention, and the Chinese medicine gout has also become a current important topic.The Five Tiger Pellet capsule is the exclusive product of Daqing Huake Company Limited. Pharmacy filiale, does not also have the bibliographical information of its treatment gout at present.
Summary of the invention
Goal of the invention: the object of the present invention is to provide the application of Five Tiger Pellet capsule in preparation treatment gout medicine.
Technical scheme: the application of Five Tiger Pellet capsule in preparation treatment gout medicine.
Five Tiger Pellet capsule Main Ingredients and Appearance is Rhizoma Polygoni Cuspidati, Caulis Sargentodoxae, Radix Salviae Miltiorrhizae, Pseudobulbus Cremastrae Seu Pleiones, Radix Knoxiae, Galla Chinensis, artificial Moschus, and is oral, one time 2; 3 times on the one, ability clearing away heat-damp and promoting diuresis, blood circulation promoting and dispersing pathogen accumulation; Be used for the chronic nonspecific prostatitis damp-heat accumulation syndrome of blood stasis of holding concurrently, the present invention finds it can treat gout.
Beneficial effect: Five Tiger Pellet capsule for treating gout, respond well.
The specific embodiment
The clinical data of Five Tiger Pellet capsule for treating gout
Case is selected: through 30 routine clinical observations.Selecting the tcm diagnosis gout is standard: the patient has hyperuricemia, often in midnight the joint have an intense pain, the joint is red, swollen, hot, bitterly at ordinary times, limitation of activity, articular cavity has hydrops, tophus occurs and precipitates.As above symptom can be made a definite diagnosis.In making a definite diagnosis the object of observation, male's 11 examples, women's 9 examples do not have other serious disease, and the age is 37 years old-62 years old, 48.7 years old mean age.
Efficacy determination: produce effects: body constitution strengthens, on one's body energetically; Hyperuricemia is controlled, and red, swollen, hot, the pain in joint are obviously alleviated; Hydrarthrosis reduces.Effectively: body constitution strengthens, on one's body energetically; Red, swollen, hot, the pain in joint alleviate to some extent.Invalid: the disease no change.
During clinical experiment, take the Five Tiger Pellet capsule, one time 2,3 times on the one, observed 6 months, be a course of treatment, take 6 months after, symptom is obviously improved, 30 philtrums, produce effects 4 people, effective 24 people, invalid 2 people, total effective rate 93.33%.
Claims (1)
1. the application of Five Tiger Pellet capsule in preparation treatment gout medicine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012102036155A CN102727752A (en) | 2012-06-19 | 2012-06-19 | Application of Wu Hu Dan capsules in preparing medicine used for treating gout |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012102036155A CN102727752A (en) | 2012-06-19 | 2012-06-19 | Application of Wu Hu Dan capsules in preparing medicine used for treating gout |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102727752A true CN102727752A (en) | 2012-10-17 |
Family
ID=46984516
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012102036155A Pending CN102727752A (en) | 2012-06-19 | 2012-06-19 | Application of Wu Hu Dan capsules in preparing medicine used for treating gout |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102727752A (en) |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003004608A2 (en) * | 2001-07-06 | 2003-01-16 | Incyte Genomics, Inc. | Drug metabolizing enzymes |
| CN1429615A (en) * | 2003-01-30 | 2003-07-16 | 庹元斌 | Chinese medicine for treating prostatitis |
| US20040087796A1 (en) * | 2001-03-28 | 2004-05-06 | Harper Richard Waltz | Substituted carbazoles as inhibitors of spla2 |
| CN1883626A (en) * | 2006-05-30 | 2006-12-27 | 陕西九州生物科技股份有限公司 | Capsule for treating gout and preparation process thereof |
| CN1899439A (en) * | 2006-06-30 | 2007-01-24 | 杨熠锴 | Chinese medicine composition for treating goat and its use |
| CN101450154A (en) * | 2007-11-28 | 2009-06-10 | 天津金世制药有限公司 | Percutaneous absorption preparation for treating gout and preparation method thereof |
-
2012
- 2012-06-19 CN CN2012102036155A patent/CN102727752A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040087796A1 (en) * | 2001-03-28 | 2004-05-06 | Harper Richard Waltz | Substituted carbazoles as inhibitors of spla2 |
| WO2003004608A2 (en) * | 2001-07-06 | 2003-01-16 | Incyte Genomics, Inc. | Drug metabolizing enzymes |
| CN1429615A (en) * | 2003-01-30 | 2003-07-16 | 庹元斌 | Chinese medicine for treating prostatitis |
| CN1883626A (en) * | 2006-05-30 | 2006-12-27 | 陕西九州生物科技股份有限公司 | Capsule for treating gout and preparation process thereof |
| CN1899439A (en) * | 2006-06-30 | 2007-01-24 | 杨熠锴 | Chinese medicine composition for treating goat and its use |
| CN101450154A (en) * | 2007-11-28 | 2009-06-10 | 天津金世制药有限公司 | Percutaneous absorption preparation for treating gout and preparation method thereof |
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| C06 | Publication | ||
| PB01 | Publication | ||
| DD01 | Delivery of document by public notice |
Addressee: Bian Yuping Document name: Notification of Approving Refund |
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| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20121017 |