CN102579818A - Traditional Tibetan medicine composition, preparation method thereof and application - Google Patents
Traditional Tibetan medicine composition, preparation method thereof and application Download PDFInfo
- Publication number
- CN102579818A CN102579818A CN2012100823423A CN201210082342A CN102579818A CN 102579818 A CN102579818 A CN 102579818A CN 2012100823423 A CN2012100823423 A CN 2012100823423A CN 201210082342 A CN201210082342 A CN 201210082342A CN 102579818 A CN102579818 A CN 102579818A
- Authority
- CN
- China
- Prior art keywords
- gets
- tibetan medicine
- kidney
- powder
- parts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 title claims abstract description 99
- 239000000203 mixture Substances 0.000 title claims abstract description 39
- 238000002360 preparation method Methods 0.000 title claims abstract description 19
- 210000003734 kidney Anatomy 0.000 claims abstract description 67
- 230000007812 deficiency Effects 0.000 claims abstract description 41
- 201000010099 disease Diseases 0.000 claims abstract description 27
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 27
- 241001233126 Paralaudakia himalayana Species 0.000 claims abstract description 26
- 238000000034 method Methods 0.000 claims abstract description 25
- 235000013336 milk Nutrition 0.000 claims abstract description 19
- 239000008267 milk Substances 0.000 claims abstract description 19
- 210000004080 milk Anatomy 0.000 claims abstract description 19
- 244000022198 Mirabilis jalapa Species 0.000 claims abstract description 12
- 235000009053 Mirabilis jalapa Nutrition 0.000 claims abstract description 12
- 229940079593 drug Drugs 0.000 claims abstract description 10
- 208000027219 Deficiency disease Diseases 0.000 claims abstract description 9
- 241000608174 Gymnadenia Species 0.000 claims abstract description 4
- 210000001835 viscera Anatomy 0.000 claims abstract description 3
- 239000000843 powder Substances 0.000 claims description 41
- 239000011812 mixed powder Substances 0.000 claims description 18
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 18
- 238000002156 mixing Methods 0.000 claims description 17
- 239000000796 flavoring agent Substances 0.000 claims description 16
- 235000019634 flavors Nutrition 0.000 claims description 16
- 241000977585 Saussurea medusa Species 0.000 claims description 15
- 239000008187 granular material Substances 0.000 claims description 14
- 239000012567 medical material Substances 0.000 claims description 14
- 239000002552 dosage form Substances 0.000 claims description 13
- 239000002775 capsule Substances 0.000 claims description 11
- 241000190633 Cordyceps Species 0.000 claims description 10
- 241000628997 Flos Species 0.000 claims description 10
- 239000000463 material Substances 0.000 claims description 8
- 230000001954 sterilising effect Effects 0.000 claims description 8
- 238000004659 sterilization and disinfection Methods 0.000 claims description 8
- 235000019998 barley wine Nutrition 0.000 claims description 6
- 238000005516 engineering process Methods 0.000 claims description 6
- 206010003549 asthenia Diseases 0.000 claims description 5
- -1 decoction Substances 0.000 claims description 5
- 230000008569 process Effects 0.000 claims description 5
- 210000002700 urine Anatomy 0.000 claims description 5
- 244000153234 Hibiscus abelmoschus Species 0.000 claims description 4
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 claims description 4
- 238000001035 drying Methods 0.000 claims description 4
- 206010022437 insomnia Diseases 0.000 claims description 4
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 4
- 206010036596 premature ejaculation Diseases 0.000 claims description 4
- 201000004384 Alopecia Diseases 0.000 claims description 3
- 230000004087 circulation Effects 0.000 claims description 3
- 238000010411 cooking Methods 0.000 claims description 3
- 239000007788 liquid Substances 0.000 claims description 3
- 238000003672 processing method Methods 0.000 claims description 3
- 235000020183 skimmed milk Nutrition 0.000 claims description 3
- 238000003756 stirring Methods 0.000 claims description 3
- 208000036119 Frailty Diseases 0.000 claims description 2
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 claims description 2
- 231100000360 alopecia Toxicity 0.000 claims description 2
- 230000001684 chronic effect Effects 0.000 claims description 2
- 238000003759 clinical diagnosis Methods 0.000 claims description 2
- 230000000249 desinfective effect Effects 0.000 claims description 2
- 238000003958 fumigation Methods 0.000 claims description 2
- 238000010438 heat treatment Methods 0.000 claims description 2
- 239000006187 pill Substances 0.000 claims description 2
- 230000001568 sexual effect Effects 0.000 claims description 2
- 230000035900 sweating Effects 0.000 claims description 2
- 239000003826 tablet Substances 0.000 claims description 2
- 235000014666 liquid concentrate Nutrition 0.000 claims 4
- 238000001694 spray drying Methods 0.000 claims 4
- 238000000605 extraction Methods 0.000 claims 2
- 238000011049 filling Methods 0.000 claims 2
- 235000008504 concentrate Nutrition 0.000 claims 1
- 239000012141 concentrate Substances 0.000 claims 1
- 238000001802 infusion Methods 0.000 claims 1
- 239000002674 ointment Substances 0.000 claims 1
- 239000006188 syrup Substances 0.000 claims 1
- 235000020357 syrup Nutrition 0.000 claims 1
- 229940098465 tincture Drugs 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 19
- 241001248610 Ophiocordyceps sinensis Species 0.000 abstract description 4
- 235000014360 Punica granatum Nutrition 0.000 abstract description 3
- 230000002265 prevention Effects 0.000 abstract description 3
- 241000305491 Gastrodia elata Species 0.000 abstract description 2
- 241000219991 Lythraceae Species 0.000 abstract description 2
- 241000159213 Zygophyllaceae Species 0.000 abstract description 2
- 241000411851 herbal medicine Species 0.000 abstract description 2
- MUKYLHIZBOASDM-UHFFFAOYSA-N 2-[carbamimidoyl(methyl)amino]acetic acid 2,3,4,5,6-pentahydroxyhexanoic acid Chemical compound NC(=N)N(C)CC(O)=O.OCC(O)C(O)C(O)C(O)C(O)=O MUKYLHIZBOASDM-UHFFFAOYSA-N 0.000 abstract 1
- 235000009165 saligot Nutrition 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 239000008280 blood Substances 0.000 description 8
- 210000004369 blood Anatomy 0.000 description 8
- 208000024891 symptom Diseases 0.000 description 8
- 208000002193 Pain Diseases 0.000 description 7
- 210000004072 lung Anatomy 0.000 description 7
- 238000012360 testing method Methods 0.000 description 7
- 206010039509 Scab Diseases 0.000 description 6
- 238000003745 diagnosis Methods 0.000 description 6
- 210000004185 liver Anatomy 0.000 description 6
- 206010011224 Cough Diseases 0.000 description 5
- 230000006870 function Effects 0.000 description 5
- 201000001881 impotence Diseases 0.000 description 5
- 230000001737 promoting effect Effects 0.000 description 5
- 208000011580 syndromic disease Diseases 0.000 description 5
- 235000013339 cereals Nutrition 0.000 description 4
- 238000005457 optimization Methods 0.000 description 4
- 231100000915 pathological change Toxicity 0.000 description 4
- 230000036285 pathological change Effects 0.000 description 4
- 210000000952 spleen Anatomy 0.000 description 4
- 239000011800 void material Substances 0.000 description 4
- 241000219470 Mirabilis Species 0.000 description 3
- 210000001015 abdomen Anatomy 0.000 description 3
- 230000017531 blood circulation Effects 0.000 description 3
- 210000001124 body fluid Anatomy 0.000 description 3
- 239000010839 body fluid Substances 0.000 description 3
- 208000002173 dizziness Diseases 0.000 description 3
- 230000000857 drug effect Effects 0.000 description 3
- 208000017169 kidney disease Diseases 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 238000012856 packing Methods 0.000 description 3
- 230000001105 regulatory effect Effects 0.000 description 3
- 210000002784 stomach Anatomy 0.000 description 3
- 230000035922 thirst Effects 0.000 description 3
- 238000005303 weighing Methods 0.000 description 3
- 201000000736 Amenorrhea Diseases 0.000 description 2
- 206010001928 Amenorrhoea Diseases 0.000 description 2
- 206010012735 Diarrhoea Diseases 0.000 description 2
- 208000000059 Dyspnea Diseases 0.000 description 2
- 206010013975 Dyspnoeas Diseases 0.000 description 2
- 208000010228 Erectile Dysfunction Diseases 0.000 description 2
- 208000019693 Lung disease Diseases 0.000 description 2
- 241000233855 Orchidaceae Species 0.000 description 2
- 241001468611 Polygonatum cyrtonema Species 0.000 description 2
- 244000294611 Punica granatum Species 0.000 description 2
- 206010037660 Pyrexia Diseases 0.000 description 2
- 210000000593 adipose tissue white Anatomy 0.000 description 2
- 231100000540 amenorrhea Toxicity 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 210000000038 chest Anatomy 0.000 description 2
- 208000013116 chronic cough Diseases 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 230000029087 digestion Effects 0.000 description 2
- 206010013781 dry mouth Diseases 0.000 description 2
- 235000013399 edible fruits Nutrition 0.000 description 2
- 241001233957 eudicotyledons Species 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 230000005714 functional activity Effects 0.000 description 2
- 230000003054 hormonal effect Effects 0.000 description 2
- 208000013403 hyperactivity Diseases 0.000 description 2
- 208000000509 infertility Diseases 0.000 description 2
- 230000036512 infertility Effects 0.000 description 2
- 231100000535 infertility Toxicity 0.000 description 2
- 230000003907 kidney function Effects 0.000 description 2
- 230000033001 locomotion Effects 0.000 description 2
- 210000003141 lower extremity Anatomy 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 230000027939 micturition Effects 0.000 description 2
- 230000036565 night sweats Effects 0.000 description 2
- 206010029410 night sweats Diseases 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 239000008194 pharmaceutical composition Substances 0.000 description 2
- 238000010791 quenching Methods 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 230000035807 sensation Effects 0.000 description 2
- 235000019615 sensations Nutrition 0.000 description 2
- 230000036299 sexual function Effects 0.000 description 2
- 239000002689 soil Substances 0.000 description 2
- 235000014347 soups Nutrition 0.000 description 2
- 208000018556 stomach disease Diseases 0.000 description 2
- 238000005728 strengthening Methods 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 235000015961 tonic Nutrition 0.000 description 2
- 230000001256 tonic effect Effects 0.000 description 2
- 230000002485 urinary effect Effects 0.000 description 2
- 238000010792 warming Methods 0.000 description 2
- 208000008286 Aortic Arch Syndromes Diseases 0.000 description 1
- 241000208173 Apiaceae Species 0.000 description 1
- 241000208306 Apium Species 0.000 description 1
- 241000233788 Arecaceae Species 0.000 description 1
- 208000006820 Arthralgia Diseases 0.000 description 1
- 208000036487 Arthropathies Diseases 0.000 description 1
- 244000248539 Asparagus cochinchinensis Species 0.000 description 1
- 235000009292 Asparagus cochinchinensis Nutrition 0.000 description 1
- 241000208838 Asteraceae Species 0.000 description 1
- 241000193738 Bacillus anthracis Species 0.000 description 1
- 208000008035 Back Pain Diseases 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 241000283690 Bos taurus Species 0.000 description 1
- 208000007333 Brain Concussion Diseases 0.000 description 1
- 244000020518 Carthamus tinctorius Species 0.000 description 1
- 235000003255 Carthamus tinctorius Nutrition 0.000 description 1
- 240000005250 Chrysanthemum indicum Species 0.000 description 1
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 description 1
- 244000192528 Chrysanthemum parthenium Species 0.000 description 1
- 235000000604 Chrysanthemum parthenium Nutrition 0.000 description 1
- 241000221751 Claviceps purpurea Species 0.000 description 1
- 206010010356 Congenital anomaly Diseases 0.000 description 1
- 206010051625 Conjunctival hyperaemia Diseases 0.000 description 1
- 206010011878 Deafness Diseases 0.000 description 1
- 206010013647 Drowning Diseases 0.000 description 1
- 208000005171 Dysmenorrhea Diseases 0.000 description 1
- 206010013935 Dysmenorrhoea Diseases 0.000 description 1
- 206010013954 Dysphoria Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 241000201295 Euphrasia Species 0.000 description 1
- 208000012895 Gastric disease Diseases 0.000 description 1
- 241000608170 Gymnadenia conopsea Species 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 241000130660 Hepialidae Species 0.000 description 1
- 208000031361 Hiccup Diseases 0.000 description 1
- 241000270355 Iguanidae Species 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 208000012659 Joint disease Diseases 0.000 description 1
- 241000234280 Liliaceae Species 0.000 description 1
- 208000008930 Low Back Pain Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 208000021891 Micturition disease Diseases 0.000 description 1
- 241000202902 Mirabilis himalaica Species 0.000 description 1
- 206010062575 Muscle contracture Diseases 0.000 description 1
- 208000007443 Neurasthenia Diseases 0.000 description 1
- 206010059013 Nocturnal emission Diseases 0.000 description 1
- 241000219469 Nyctaginaceae Species 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 206010034568 Peripheral coldness Diseases 0.000 description 1
- 241000233805 Phoenix Species 0.000 description 1
- 241000244271 Pleurospermum Species 0.000 description 1
- 241000037826 Polygonatum kingianum Species 0.000 description 1
- 241000037831 Polygonatum sibiricum Species 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 208000037656 Respiratory Sounds Diseases 0.000 description 1
- 208000025747 Rheumatic disease Diseases 0.000 description 1
- 208000033809 Suppuration Diseases 0.000 description 1
- 208000001106 Takayasu Arteritis Diseases 0.000 description 1
- 241000330896 Thitarodes armoricanus Species 0.000 description 1
- 241001533104 Tribulus terrestris Species 0.000 description 1
- 208000006568 Urinary Bladder Calculi Diseases 0.000 description 1
- 208000012886 Vertigo Diseases 0.000 description 1
- 241000608575 Vespertilio Species 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 208000031971 Yin Deficiency Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 238000007605 air drying Methods 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000001139 anti-pruritic effect Effects 0.000 description 1
- 239000003908 antipruritic agent Substances 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000008827 biological function Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 230000002612 cardiopulmonary effect Effects 0.000 description 1
- 208000026915 cervical aortic arch Diseases 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 208000006111 contracture Diseases 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 239000003866 digestant Substances 0.000 description 1
- 210000002249 digestive system Anatomy 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 235000006694 eating habits Nutrition 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 239000003172 expectorant agent Substances 0.000 description 1
- 230000003419 expectorant effect Effects 0.000 description 1
- 210000003414 extremity Anatomy 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 235000008384 feverfew Nutrition 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 210000004209 hair Anatomy 0.000 description 1
- 230000003676 hair loss Effects 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 208000023513 hiccough Diseases 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 239000002917 insecticide Substances 0.000 description 1
- 210000000629 knee joint Anatomy 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 201000003453 lung abscess Diseases 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 208000004396 mastitis Diseases 0.000 description 1
- 230000035800 maturation Effects 0.000 description 1
- 238000002483 medication Methods 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 235000013379 molasses Nutrition 0.000 description 1
- 210000000653 nervous system Anatomy 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 210000002826 placenta Anatomy 0.000 description 1
- 230000000171 quenching effect Effects 0.000 description 1
- 210000000664 rectum Anatomy 0.000 description 1
- 230000003014 reinforcing effect Effects 0.000 description 1
- 210000004994 reproductive system Anatomy 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 230000000552 rheumatic effect Effects 0.000 description 1
- 201000005404 rubella Diseases 0.000 description 1
- 206010040872 skin infection Diseases 0.000 description 1
- 229960000716 tonics Drugs 0.000 description 1
- 238000012549 training Methods 0.000 description 1
- 230000008736 traumatic injury Effects 0.000 description 1
- 231100000889 vertigo Toxicity 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
Images
Landscapes
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention discloses a traditional Tibetan medicine composition, takes examples by the experience of traditional Tibetan medicine in prevention and treatment of kidney deficiency diseases, selects traditional Tibetan medicines for reasonable matching, and provides the traditional Tibetan medicine composition with herbal medicines serving as main components. The Tibetan medicine composition adopts agama himalayana, radix pleurospermi tibetanic, rhizoma polygonati, Himalaya mirabilis jalapa, caltrop, radix asparagi, medusa maxim and milk as a basic formula, and under a preferable condition, other Tibetan medicine components including seeds of pomegranates, red flowers, cordyceps sinensis, conic gymnadenia tuber, gastrodia elata and the like can be further added. A preparation method of the Tibetan medicine composition and the application of the method in the preparation of the medicine for treating the kidney deficiency diseases are further provided. The traditional Tibetan medicine composition directly acts on a human body visceral organ, is verified by clinic experiments to be capable of being applied to treatment of deficiency of kidney yin and yang diseases, is remarkable in medicine efficiency, short in curative period and free of toxic and side effect.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition, particularly relate to a kind of Tibetan medicine compositions that can be used to prepare treatment kidney deficiency disease drug.
Background technology
The notion of traditional medicine said " kidney " and western medicine said " kidney " have very big-difference.The said kidney of doctor trained in Western medicine is an anatomical concepts, refers to a pair of organ in the urinary system.Kidney in the traditional medicine is a functional concept, the functional activity of a plurality of systems in the general reference human body, and be not a certain certain organs.Kidney in the traditional medicine is participated in most of biological function of the vital movement, particularly regulating and controlling hormonal system of human body hormonal system, nervous system, urinary system, motor system, respiratory system, digestive system, reproductive system 7 big systems.The vital essence of kidney is dominated the whole life process of human growth, growth, maturation, death, so kidney is called " the congenital foundation " by traditional medicine.
Suffering from a deficiency of the kidney is the peculiar notion of traditional medical theory, and general reference is because of the not enough a plurality of systems disease that causes of kidney essense gas negative and positive in the human body.According to the yin or yang excess difference that declines partially of essence in kidney, suffering from a deficiency of the kidney comprises the different performances such as void, instability of kidney QI, failure of the kidney in receiving QI, kidney yin kidney yang two void, deficiency of the kidney yin hyperactivity of fire thanks to of deficiency of kidney-YIN, kidney yang.Clinically, generally be divided into two kinds of syndrome of deficiency of kidney yin and syndrome of deficiency of kidney-YANG briefly.The main performance of suffering from a deficiency of the kidney is: Hiccough and deaf, loss of hairs withered worried, luxated tooth is sparse, aching pain in waist and back, shank are soft, talalgia, sexual function are not normal, CHI-pulse being weak etc.Deficiency of the kidney yin can have dysphoria with feverish sensation in the chest palms and soles, insomnia, dreaminess, night sweat, dry mouth and throat concurrently, has a dizzy spell on the symptom basis of suffering from a deficiency of the kidney, nocturnal emission, afternoon flushed cheeks, the few tongue of red tongue or symptoms such as crackle, thready and rapid pulse are arranged.Insufficiency of kidney-YANG can have pale complexion, cold extremities concurrently, creeping chill, clear urine in large amounts, watery diarrhea with indigested food are arranged below the abdomen, has loose bowels just before dawn on the symptom basis of suffering from a deficiency of the kidney, frequent micturition, emission, impotence and premature ejaculation, the back heeltap of drowning, leukorrhagia are rare clearly, infertility, hydroderma, foot is swollen, lower limb is swollen, light red tongue is fat, white and moist fur, faint and weak pulse and symptom such as slow.
In the Tibetanmedicine rationale, the three big factors that exist in the human body, seven kinds of materials and three kinds of material bases that the common formation of Excreta earns a bare living.Three big factors " are swelled ", among " red crust ", " Baconic ", grand is gas, accumulates in brains, cardiopulmonary and the skeleton, be responsible for breathe, circulation, sensation, motion; Red crust is a fire, is dispersed in liver and the blood generation of facilitating digestion, absorption and heat energy and wisdom; Baconic is a water and soil, is present in spleen, stomach, intravesical, can regulate digestion and water balance, influences people's body weight and disposition.In the human body, kidney has " water ", " soil " character, has the body fluid of generation and metabolic important function.Because grand in the body, red crust, Baconic's three categories of etiologic factors procatarxis are inside and outside, and certain is former thereby occur can causing renal function unbalance when too prosperous or on the decline, and body disease takes place.Particularly human body is in wet environment or reason such as contact cold water etc. for a long time, and has a liking for sweet or have a liking for raw and cold dietary habit etc., all can make the vital essence negative and positive of kidney in the human body not enough, causes the pathological changes of multiple human body physiological system, and causes the disease of suffering from a deficiency of the kidney.Tradition Tibetan medicine theory is divided into 8 major types with kidney disease; Wherein the suffer from a deficiency of the kidney disease of the renal function imbalance that is mainly cold pathological changes, the described deficiency of kidney-YIN of similar Chinese medicine, kidney yang are lost different manifestations such as void, instability of kidney QI, failure of the kidney in receiving QI, kidney yin kidney yang two void, deficiency of the kidney yin hyperactivity of fire.The Tibetan medicine clinically, generally also will suffer from a deficiency of the kidney and briefly be divided into triumphant plan card (insufficiency of kidney-YANG) and two kinds of triumphant normal cards (deficiency of the kidney yin).
Healthwise evaluation with western medicine; The alleged disease of suffering from a deficiency of the kidney of traditional medicine is not special finger kidney organ's a pathological changes, and it belongs to the sub-health state of the multiple functional system function of body comprehensive pathological changes of the uncomfortable body that causes or the decline of animal economy function level in essence.
Tibetanmedicine in the traditional medicine results from area, China Qinghai-Tibet Platean; Long-term specific aim alleviates with control because height above sea level, air drying be thin etc., and the plateau severe environmental conditions takes place with disease to the physical function burden that the local resident causes, and aspect the functional activity adjusting of human body multisystem, is accumulating a large amount of experiences.
Summary of the invention
The object of the invention is exactly the deficiency to prior art, and a kind of Tibetan medicine compositions that can be used to prepare treatment kidney deficiency disease drug is provided.
For realizing above-mentioned purpose, technical scheme of the present invention is following:
A kind of Tibetan medicine compositions is characterized in that: contain 10～60 parts of Agama himalayana, 40～80 parts of Herba pleurospermi thomsoniis, 40～70 parts of Rhizoma Polygonatis, 40～60 parts of Himalaya Mirabilis jalapas, 40～70 parts of Fructus Tribulis, 40～60 parts of Radix Asparagi, 20～50 parts of Saussurea medusa Maxim., 20～40 parts in milk.
In the above-mentioned Tibetan medicine compositions:
Agama himalayana is recorded in " first of the Sanitation Ministry medicine standard Tibetan medicine " (standard numbering WS3-BC-0102-95, Tibetan medicine title: hide crust), is the dry all of Iguanidae animal Agama himalayana (Agama himalayana).Main effect is Yang nourishing-strengthening.Be used for the renal cold disease, sexual impotence, diseases such as seminal emission.
Herba pleurospermi thomsonii (Tibetan medicine title: add) is the dry herb of dicotyledon medicine Umbelliferae rib apium plant Herba pleurospermi thomsonii (Pleurospermum Hoffm).Main effect is regulating QI to relieve pain, blood circulation promoting and blood stasis dispelling.
Rhizoma Polygonati (Tibetan medicine title: La Ni), be the dry rhizome of liliaceous plant Yunnan Rhizoma Polygonati (Polygonatum kingianum Coll.et Hemsl.), Rhizoma Polygonati (P.sibiricum Red.) or Polygonatum cyrtonema Hua (P.cyrtonema Hua).Return spleen, lung, kidney channel.Main effect is spleen reinforcing, the lung moistening and production of body fluid promoting, is used for weakness of the spleen and stomach, deficiency of the lung cough caused by dryness, interior-heat and quenches one's thirst.
Radix Mirabilis himalaicae is recorded in " Tibetan medicine is promulgated by the ministries or commissions of the Central Government " (standard No.: WS3-BC-0103-95, Tibetan language title: crust Zhu), be the dry root of Nyctaginaceae plant Radix Mirabilis himalaicae (Mirabilis himalaica (Edgew.) Heim.).Function is the kidney warming, granulation promoting, diuresis, calculus, yellow fluid reducing with curing mainly.Be used for cold syndrome of the stomach, renal cold, following coldness of the body, sexual impotence edema, vesical calculus, lumbago, arthralgia, yellow fluid pain.
Fructus Tribuli (Tibetan medicine title: Sai Ma), be the dry mature fruit of zygophyllaceae plant Fructus Tribuli (Tribulus terrestris L.).Return Liver Channel.Main effect is the suppressing the hyperactive liver resolving depression, and promoting blood circulation by removing wind makes eye bright, and is antipruritic.It is dizzy to be used to have a headache, distending pain in the chest and hypochondrium, and breast closes acute mastitis, conjunctival congestion cataracta, rubella pruritus.
Radix Asparagi is the tuber of Liliaceae asparagus plant Radix Asparagi (Asparagus cochinchinensis).Main effect is to control the consumptive lung disease lung abscess, and vomiting pus is spitted blood, phlegmatic cough dyspnea with rapid and short breath, the choke universe of quenching one's thirst.The foot burning pain, asthenia hectic fever due to YIN-deficiency, the deficiency of YIN have the card of fire.
Saussurea medusa Maxim. (the Tibetan medicine title: just fruit Soviet Union clings to) is the herb of Compositae phoenix hair Chrysanthemum plant Saussurea medusa Maxim. (Saussurea medusa Maxim.).Main effect is to cure mainly anthrax, contracture of the limbs, and aortic arch syndrome, He Ruhu, rheumatic arthropathy, the old skin infection, sword is hindered hemorrhage, cerebral concussion, amenorrhea, placenta retention.
Milk is the medicinal herbs most in use in the Tibetan medicine.According to " brilliant pearl book on Chinese herbal medicine " record, the flavor of milk and change flavor are all sweet, the property profit; The flourish color of effect, training unit, benefit is smart; Nutrition, long fat, naughty skin, ortho sleep are provided, and property is heavy and cool, and can neutralize is dispersed in heat energy in liver and the blood; Have regulate body temperature, keep complexion, give birth to wisdom, digestant effect.Wherein with the nourishing of cattle milk, sharp lung disease, lung obstinate disease, treatment blood, red crust complication, pestilence with the passing of time, frequent micturition disease, gas have some setbacks, expectorant is unfavorable, tiredly cut down unable, giddy and revolve, and can support Rong Zengli.
Above-mentioned Tibetan medicine compositions is the basis with traditional Tibetanmedicine to the pathological study of the disease of suffering from a deficiency of the kidney; To aching pain in waist and back, shank is soft, sexual function is not normal, insomnia, dreaminess, night sweat, dry mouth and throat, have a dizzy spell, frequent micturition, emission, impotence and premature ejaculation, infertility, hydroderma, foot is swollen, lower limb is swollen, light red tongue is fat, white and moist fur, faint and weak pulse and men and women's property such as slow are suffered from a deficiency of the kidney disease the temperature compensation of suiting the medicine to the illness and this Therapeutic Principle being processed support smart, the combined pharmaceutical formulation of QI and blood mediation.Analysis is by the cause of disease, the focus of the various disease conditions due to the kidney essense QI-insufficiency; Choose several flavors such as Rhizoma Polygonati, Herba pleurospermi thomsonii, Fructus Tribuli, Radix Mirabilis himalaicae, Radix Asparagi and be widely used in traditional Tibetan medicine material of suffering from a deficiency of the kidney and treating, selected Agama himalayana, Saussurea medusa Maxim., milk 3 flavor Tibetan medicine materials simultaneously for use.Wherein, though Agama himalayana records the effect of " being used for the renal cold disease " in Tibetan medicine standard promulgated by the ministries or commissions of the Central Government, be not disclosed at present any treatment and suffer from a deficiency of the kidney in the Tibetan medicine composition component of disease.This Tibetan medicine compositions, is carried out many-sided body function to the disease of suffering from a deficiency of the kidney and is regulated through the rational proportion to selected medical material according to the medical knowledge of traditional medicine " warming and recuperating the kidney-YANG nourishes kidney yin ", reaches therapeutic purposes.
With above-mentioned 8 flavor medicines is basic recipe, and this Tibetan medicine composite formula can also be expanded optimization, to strengthen drug effect.Specifically be also to contain 30～50 parts of Semen Granati, 28～50 parts on Flos Carthami, 1～5 part of Cordyceps, 20～50 parts of Rhizoma Gymnadeniaes, 14～30 parts in Rhizoma Gastrodiae.
Semen Granati is recorded in " first of the Sanitation Ministry medicine standard Tibetan medicine " (standard numbering WS3-BC-0026-95, Tibetan medicine title: match Zhu), be Punicaceae plant pomegranate (Punica granatum L.) dry seed.Cure mainly Baconic's sympotoms caused by cold factors, cold syndrome of the stomach disease and all gastropathy.
Flos Carthami, the another name Flos Carthami is the tubular flower of dicotyledon medicine feverfew Flos Carthami (Carthamus tinctorius L.).Main effect be to invigorate blood circulation latus rectum, eliminating stasis to stop pain.Be used for that amenorrhea, dysmenorrhea, lochia are not all right, lump in the abdomen mass in the abdomen, traumatic injury.
Cordyceps has another name called Cordyceps, Cordyceps, Cordyceps sinensis.Be that section ergot fungus cordyceps sinensis bacterium (Cordyceps sinensis) colonizes in Stroma and the larva cadaveric complex on Hepialidae insecticide Vespertilio moth (the Hepialus armoricanus Oberthur) larva that survives the winter.Return lung, kidney channel.Main effect is invigorating the lung and the kidney, hemostasis and phlegm.Be used for the chronic cough dyspnea due to deficiency, the chronic cough spitting of blood, impotence and seminal emission, soreness of waist and knee joint is the famousst and precious strengthening by means of tonics medicine that has won fame both at home and abroad.
Rhizoma Gymnadeniae is recorded in " Tibetan medicine is promulgated by the ministries or commissions of the Central Government " (standard No.: WS3-BC-0015-95, Tibetan language title: prosperous drawing); Have another name called Rhizoma Gymnadeniae; Be the dry tuber of orchid Rhizoma Gymnadeniae (Gymnadenia conopsea R.Br.), have the effect of benefiting vital QI and blood, promoting the production of body fluid to quench thirst, to cough and asthma due to lung deficiency, asthenia become thin, aspect such as neurasthenia has very high health preserving and is worth; Mainly edible on Tibet and other places as tonic, commonly usedly steep in wine, praise soup or boil.
Rhizoma Gastrodiae is the dry tuber of orchid Rhizoma Gastrodiae (Gastrodia elata Bl.).Rhizoma Gastrodiae embellishes but not dry, and the master goes into Liver Channel, is longer than suppressing the hyperactive liver to relieve the wind syndrome, and the disease of all liver-wind stirring up internallys, the vertigo is no matter deficiency and excess all is important medications.
The present invention also provides the application of above-mentioned Tibetan medicine compositions in preparation treatment kidney deficiency disease drug.
Tibetan medicine compositions provided by the invention comprises the insufficiency of kidney-YANG (triumphant plan disease) or the deficiency of the kidney yin (triumphant normal disease) of clinical diagnosis through the disease of suffering from a deficiency of the kidney that the clinical trial checking can be applied to prevent and treat multiple crowd.Particularly with have a delicate constitution, tired, the chronic problem of spirit, urine are not normal, alopecia, forgetful, sweating due to debility, insomnia, sexual hypofunction, urine urgency-frequency, premature ejaculation etc. serve as multiple crowd's kidney deficiency disease of showing disease.
The present invention also provides above-mentioned Tibetan medicine preparation of compositions method simultaneously, and concrete scheme is following:
Above-mentioned Tibetan medicine preparation of compositions method is characterized in that: each medical material component is disposed in proportion, according to traditional patent medicine processing method, add in case of necessity that acceptable auxiliary is prepared into different dosage form on the pharmaceutics.
Specific dosage forms for oral administration can be a variety of dosage forms such as capsules, powders, granules, pills, tablets, soups, creams, wine, molasses, oil cakes drugs, etc. You concentrated.
Compared with prior art, the invention has the beneficial effects as follows: tradition medical material common, commonly used is prepared from according to traditional Tibetan medicine concocting method in (1) this Tibetan medicine compositions employing Tibetan medicine and pharmacology, is that former medicine of medical material or method for preparing are all safe and reliable; (2) the Tibetan medicine compositions be applied to prevent and treat multiple crowd suffer from a deficiency of the kidney the disease drug effect significantly, short treating period, have no side effect.
Description of drawings
Fig. 1 is basic components capsule, powder preparation flow figure.
Fig. 2 is expansion optimization of C capsule, powder preparation flow figure.
Fig. 3 is basic components granule preparation flow figure.
Fig. 4 is expansion optimization of C granule preparation flow figure.
The specific embodiment
Below in conjunction with accompanying drawing, the preferred embodiments of the present invention are further described.
Embodiment one
As shown in Figure 1, the preparation of Tibetan medicine composition capsule dosage form.
Tibetan medicine composition component and weight proportion thereof are: 10～60 parts of Agama himalayana, 40～80 parts of Herba pleurospermi thomsoniis, 40～70 parts of Rhizoma Polygonatis, 40～60 parts of Himalaya Mirabilis jalapas, 40～70 parts of Fructus Tribulis, 40～60 parts of Radix Asparagi, 20～50 parts of Saussurea medusa Maxim., 20～40 parts in milk.
The following prepared of concrete employing:
Step S1, get Herba pleurospermi thomsonii, Himalaya Mirabilis jalapa, Fructus Tribuli, Rhizoma Polygonati, Radix Asparagi, Saussurea medusa Maxim. 6 flavor medical materials and adopt the decocting cooking methods to extract, extracting solution;
Amount of water is 11～13 times of medical material volume during decoction, decocts 100 ℃～107 ℃ of temperature; Decoct twice, each 3.5～4.5hr; It is subsequent use to get twice decoction extracting solution mixing.
Step S2, get step S1 gained extracting solution and add the milk mixing while hot and boil 20～40min altogether, boil liquid altogether and be concentrated into 0.8～1.0 ° of B é of Baume degrees, spray-dried again extract powder;
Milk is preferably fresh not skim milk.Extracting solution and milk boil for 88 ℃～105 ℃ altogether.
Step S3, get Agama himalayana and be processed as fine powder, with step 2 gained extract powder mixing, mixed powder.
The optimum condition of extract powder and Agama himalayana powder married operation is for to mix 30～40min in the 85rpm grinder-mixer.
Step S4, get step 3 gained mixed powder and cross 80 mesh sieves, sterilization, capsule charge 0.4g/ grain.
Disinfecting action is selected the ozone fumigation for use, and operating condition is density 1.68, circulation 2hr, arranges 18 ℃～26 ℃ of 2hr, temperature, humidity 45%～65% entirely.
Embodiment two
As shown in Figure 2, the preparation of Tibetan medicine composition capsule dosage form.
Tibetan medicine composition component and weight proportion thereof are: 10～60 parts of Agama himalayana, 40～80 parts of Herba pleurospermi thomsoniis, 40～70 parts of Rhizoma Polygonatis, 40～60 parts of Himalaya Mirabilis jalapas, 40～70 parts of Fructus Tribulis, 40～60 parts of Radix Asparagi, 20～50 parts of Saussurea medusa Maxim., 20～40 parts in milk, 30～50 parts of Semen Granati, 28～50 parts on Flos Carthami, 1～5 part of Cordyceps, 20～50 parts of Rhizoma Gymnadeniaes, 14～30 parts in Rhizoma Gastrodiae.
Step S1～step S2 is with embodiment one.
Step S3, get Agama himalayana, Semen Granati, Flos Carthami, Cordyceps, Rhizoma Gymnadeniae, Rhizoma Gastrodiae 6 flavor medical materials and be processed as fine powder, with step 2 gained extract powder mixing, mixed powder.
The optimum condition of extract powder and medical material fine powder married operation is for to mix 30～40min in the 85rpm grinder-mixer.
Step S4, get step 3 gained mixed powder and cross 80 mesh sieves, sterilization, capsule charge 0.4g/ grain.
Embodiment three
As shown in Figure 2, the preparation of Tibetan medicine compositions powder.
Tibetan medicine composition component and weight proportion thereof are with embodiment two.
Step S1～step S3 is with embodiment two.
Step S4, get step 3 gained mixed powder and cross 80 mesh sieves, sterilization, packing.
Embodiment four
As shown in Figure 3, the preparation of Tibetan medicine composition grain dosage form.
Tibetan medicine composition component and weight proportion thereof are with embodiment one.
Step S1, get Herba pleurospermi thomsonii, Rhizoma Polygonati, Himalaya Mirabilis jalapa, Fructus Tribuli, Radix Asparagi, Saussurea medusa Maxim. 6 flavor Tibetan medicine materials according to formula proportion and adopt the decocte with water methods to extract, extracting solution.
Amount of water is 11～13 times of medical material volume during decoction, decocts 100 ℃～107 ℃ of temperature; Decoct twice, each 3.5～4.5hr; It is subsequent use to get twice decoction extracting solution mixing.
Step S2, get step S1 gained extracting solution and add the milk mixing while hot and boil 20～40min altogether, boil liquid altogether and be concentrated into 0.8～1.0 ° of B é of Baume degrees, spray-dried again extract powder.
Milk is preferably fresh not skim milk.Extracting solution and milk boil for 88 ℃～105 ℃ altogether.
Step S3, get Agama himalayana and be processed as fine powder, with step 2 gained extract powder mixing, mixed powder.
The optimum condition of extract powder and Agama himalayana powder married operation is for to mix 30～40min in the 85rpm grinder-mixer.
Step S4, get step S3 gained mixed powder and cross 80 mesh sieves, according to medicated powder: water (W/W)=ratio added water in 2: 1, granulate, drying, granulate is crossed 24 mesh sieves, sterilization, granule, packing.
Be excipient with water in this step.Dry moisture is controlled to be 2% according to conventional index.
Embodiment five
As shown in Figure 4, the preparation of Tibetan medicine composition grain dosage form.
Tibetan medicine composition component and weight proportion thereof are with embodiment two.
Step S1, get Herba pleurospermi thomsonii, Rhizoma Polygonati, Himalaya Mirabilis jalapa, Fructus Tribuli, Radix Asparagi, Saussurea medusa Maxim., Semen Granati, Flos Carthami, Cordyceps, Rhizoma Gymnadeniae, Rhizoma Gastrodiae 12 flavor Tibetan medicine materials according to formula proportion and adopt the decocte with water methods to extract, extracting solution.
Amount of water is 11～13 times of medical material volume during decoction, decocts 100 ℃～107 ℃ of temperature; Decoct twice, each 3.5～4.5hr; It is subsequent use to get twice decoction extracting solution mixing.
Step S2～step S4 is with embodiment four.
Embodiment six
The process of preparing Chinese medicine of Agama himalayana.
In the Tibetan medicine preparation of compositions method of above-mentioned each embodiment record, the concocting method of Agama himalayana can be improved, to strengthen its drug effect.Concrete grammar is: earlier Agama himalayana is put to death, remove internal organs, head, afterbody, clear water is cleaned, and bubble is gone into traditional highland barley wine; In barley wine, add Moschus, stir while adding, addition is for beginning to smell the Moschus flavor, and container is added a cover and soaked 8～10hr; Heating barley wine to 60 ℃～70 ℃ is cooled to 25 ℃～35 ℃, takes out Agama himalayana, and cold water is cleaned, and it is subsequent use to dry in the shade.
This Tibetan medicine compositions can be processed multiple peroral dosage form according to traditional Tibetan medicine processing method, is not limited to the technical scheme of above each embodiment record.
Test Example one
Embodiment one, four makes the Tibetan medicine compositions and processes the application of agent in disease is suffered from a deficiency of the kidney in treatment with prevention.Table 1 seen in sufferer diagnosis and treatment record.
Table 1 sufferer diagnosis and treatment records (13 example)
Test Example two
Embodiment two, three, five makes the Tibetan medicine compositions and processes the application of agent in disease is suffered from a deficiency of the kidney in treatment with prevention.
Table 2 seen in sufferer diagnosis and treatment record.Curative effect determinate standard is divided into reference to " new Chinese medicine clinical research guideline ": clinical recovery: the symptom of suffering from a deficiency of the kidney, sign disappear; Produce effects: the symptom of suffering from a deficiency of the kidney, sign are obviously improved; Effectively: the symptom of suffering from a deficiency of the kidney, sign all take a favorable turn, and be invalid: the symptom of suffering from a deficiency of the kidney, sign no change.Sufferer diagnosis and treatment curative effect statistics is seen table 3.
Table 2 sufferer diagnosis and treatment records (26 example)
The continuous table of going up
Table 3 sufferer diagnosis and treatment curative effect statistics (100 example)
| Clinical recovery | Produce effects | Effectively | Invalid | Amount to | |
| Sufferer number (example) | 10 | 30 | 50 | 10 | 100 |
| Curative effect ratio (%) | 10 | 30 | 50 | 10 | 100 |
Test Example one, two data show Tibetan medicine compositions of the present invention basic recipe and expansion optimization of C all can effectively be applied to prevent and treat the preparation of kidney deficiency disease drug.
Test Example three
The test of mixed powder measurement of water-content coefficient.
Each dosage form prepares the gained mixed powder and carries out the measurement of water-content coefficient test, and every kind of dosage form repeats 2 tests, and data record sees attached list 4.Each dosage form machines the preceding moisture content of packing capsule＜9.0%, powder moisture content＜9.0%, granule moisture content＜6.0%, all meets the NF standard.
Subordinate list 4 mixed powder moisture content
Annotate: the empty weighing botle weight of W1-; Empty weighing botle weight of W2-and medicated powder weight; Empty weighing botle and medicated powder weight after the W3-drying.
Claims (10)
1. a Tibetan medicine compositions is characterized in that: contain 10～60 parts of Agama himalayana, 40～80 parts of Herba pleurospermi thomsoniis, 40～70 parts of Rhizoma Polygonatis, 40～60 parts of Himalaya Mirabilis jalapas, 40～70 parts of Fructus Tribulis, 40～60 parts of Radix Asparagi, 20～50 parts of Saussurea medusa Maxim., 20～40 parts in milk.
2. Tibetan medicine compositions according to claim 1 is characterized in that: also contain 30～50 parts of Semen Granati, 28～50 parts on Flos Carthami, 1～5 part of Cordyceps, 20～50 parts of Rhizoma Gymnadeniaes, 14～30 parts in Rhizoma Gastrodiae.
3. Tibetan medicine preparation of compositions method according to claim 1 and 2 is characterized in that: each medical material component is disposed in proportion, according to traditional patent medicine processing method, add in case of necessity that acceptable auxiliary is prepared into different dosage form on the pharmaceutics.
4 according to the method of claim 3, wherein: said dosage forms include capsules, powders, granules, pills, tablets, decoction, ointment, tincture, syrup, oil cakes drugs, You concentrate.
5. method for preparing according to claim 3 is characterized in that: prepare according to one of following process:
Technology one: step S1 gets Herba pleurospermi thomsonii, Himalaya Mirabilis jalapa, Fructus Tribuli, Rhizoma Polygonati, Radix Asparagi, Saussurea medusa Maxim. 6 flavor medical materials employing decocting cooking methods extractions according to formula proportion, gets extracting solution; Step S2 gets step S1 gained extracting solution and adds the milk mixing and boil altogether, boils altogether that liquid concentrates, spray drying gets extract powder; Step 3 is got Agama himalayana and is processed as fine powder, with step 2 gained extract powder mixing, gets mixed powder; Step S4, step 3 gained mixed powder sieves, and sterilization makes powder or filling becomes capsule;
Technology two: step S1 gets Herba pleurospermi thomsonii, Himalaya Mirabilis jalapa, Fructus Tribuli, Rhizoma Polygonati, Radix Asparagi, Saussurea medusa Maxim. 6 flavor medical materials employing decocting cooking methods extractions according to formula proportion, gets extracting solution; Step S2 gets step S1 gained extracting solution and adds the milk mixing and boil altogether, boils altogether that liquid concentrates, spray drying gets extract powder; Step 3 is got Agama himalayana, Semen Granati, Flos Carthami, Cordyceps, Rhizoma Gymnadeniae, Rhizoma Gastrodiae 6 flavor medical materials and is processed as fine powder, gets mixed powder with step 2 gained extract powder mixing; Step S4, step 3 gained mixed powder sieves, and sterilization makes powder or filling becomes capsule;
Technology three: step S1, get Herba pleurospermi thomsonii, Rhizoma Polygonati, Himalaya Mirabilis jalapa, Fructus Tribuli, Radix Asparagi, Saussurea medusa Maxim. 6 flavor Tibetan medicine materials according to formula proportion and adopt the decocte with water methods to extract, extracting solution; Step S2 gets step S1 gained extracting solution and adds the milk mixing and boil altogether, boils altogether that liquid concentrates, spray drying gets extract powder; Step S3 gets Agama himalayana and is processed as fine powder, with step 2 gained extract powder mixing, gets mixed powder; Step S4, step S3 gained mixed powder sieves, and adding entry is excipient, granulate, drying, granulate sieves, and sterilization gets granule;
Technology four: step S1, get Herba pleurospermi thomsonii, Rhizoma Polygonati, Himalaya Mirabilis jalapa, Fructus Tribuli, Radix Asparagi, Saussurea medusa Maxim., Semen Granati, Flos Carthami, Cordyceps, Rhizoma Gymnadeniae, Rhizoma Gastrodiae 12 flavor Tibetan medicine materials according to formula proportion and adopt the decocte with water methods to extract, extracting solution; Step S2 gets step S1 gained extracting solution and adds the milk mixing and boil altogether, boils altogether that liquid concentrates, spray drying gets extract powder; Step S3 gets Agama himalayana and is processed as fine powder, with step 2 gained extract powder mixing, gets mixed powder; Step S4, step S3 gained mixed powder sieves, and adding entry is excipient, granulate, drying, granulate sieves, and sterilization gets granule.
6. method according to claim 5 is characterized in that: among the said step S2, extracting solution adds fresh not skim milk mixing, and 88 ℃～105 ℃ are boiled 20～40min altogether, boil liquid altogether and are concentrated into 0.8～1.0 ° of B é of Baume degrees, the spray-dried again extract powder that gets; Said step 3 extract powder is in the 85rpm grinder-mixer, to mix 30～40min with medicated powder married operation condition; Said disinfecting action is the ozone fumigation, and operating condition is density 1.68, circulation 2hr, arranges 18 ℃～26 ℃ of 2hr, temperature, humidity 45%～65% entirely; In the said technology three or four, the excipient addition is a medicated powder: water (W/W)=2: 1.
7. according to claim 5 or 6 described methods, it is characterized in that: said Agama himalayana concocting method is: Agama himalayana is put to death, and removes internal organs, head, afterbody, cleans; Bubble is gone into traditional highland barley wine, in barley wine, adds Moschus, stirs while adding, and addition is for beginning to smell the Moschus flavor; Infusion 8～10hr, heating barley wine to 60 ℃～70 ℃ is cooled to 25 ℃～35 ℃; Take out Agama himalayana, cold water is cleaned, and it is subsequent use to dry in the shade.
8. the application of Tibetan medicine compositions according to claim 1 and 2 in preparation treatment kidney deficiency disease drug.
9. application according to claim 8 is characterized in that: deficiency of the kidney yin that the said disease of suffering from a deficiency of the kidney is clinical diagnosis or insufficiency of kidney-YANG disease.
10. application according to claim 9 is characterized in that: the said disease of suffering from a deficiency of the kidney be with have a delicate constitution, tired, the chronic problem of spirit, urine are not normal, alopecia, forgetful, sweating due to debility, insomnia, sexual hypofunction, urine urgency-frequency, premature ejaculation etc. serve as multiple crowd's kidney deficiency disease of showing disease.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210082342.3A CN102579818B (en) | 2012-03-26 | 2012-03-26 | Traditional Tibetan medicine composition, preparation method thereof and application |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210082342.3A CN102579818B (en) | 2012-03-26 | 2012-03-26 | Traditional Tibetan medicine composition, preparation method thereof and application |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102579818A true CN102579818A (en) | 2012-07-18 |
| CN102579818B CN102579818B (en) | 2014-01-08 |
Family
ID=46469419
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210082342.3A Active CN102579818B (en) | 2012-03-26 | 2012-03-26 | Traditional Tibetan medicine composition, preparation method thereof and application |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102579818B (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103961565A (en) * | 2014-05-22 | 2014-08-06 | 卢祥平 | Externally-applied medicine for enhancing renal function |
| CN107714955A (en) * | 2017-11-14 | 2018-02-23 | 乡城藏青兰药业有限公司 | The concocting method of rhizoma Gastrodiae |
| CN111821379A (en) * | 2020-07-17 | 2020-10-27 | 西藏藏医药大学 | Preparation method of Tibetan medicine Basang mu ghee pill soft capsule for improving immunity |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1899565A (en) * | 2006-07-04 | 2007-01-24 | 洛嘎 | Morning oral administration Tibetan medicine for treating diabetes and its preparing method |
| CN1919225A (en) * | 2006-09-18 | 2007-02-28 | 中国人民解放军军事医学科学院生物工程研究所 | Application of cultured saussurea medusa and extract thereof in preparation of medicine for treating II type diabetes and its complications |
| CN102366540A (en) * | 2011-09-28 | 2012-03-07 | 久美彭措 | Medicine for treating diabetes and its preparation method |
-
2012
- 2012-03-26 CN CN201210082342.3A patent/CN102579818B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1899565A (en) * | 2006-07-04 | 2007-01-24 | 洛嘎 | Morning oral administration Tibetan medicine for treating diabetes and its preparing method |
| CN1919225A (en) * | 2006-09-18 | 2007-02-28 | 中国人民解放军军事医学科学院生物工程研究所 | Application of cultured saussurea medusa and extract thereof in preparation of medicine for treating II type diabetes and its complications |
| CN102366540A (en) * | 2011-09-28 | 2012-03-07 | 久美彭措 | Medicine for treating diabetes and its preparation method |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103961565A (en) * | 2014-05-22 | 2014-08-06 | 卢祥平 | Externally-applied medicine for enhancing renal function |
| CN107714955A (en) * | 2017-11-14 | 2018-02-23 | 乡城藏青兰药业有限公司 | The concocting method of rhizoma Gastrodiae |
| CN111821379A (en) * | 2020-07-17 | 2020-10-27 | 西藏藏医药大学 | Preparation method of Tibetan medicine Basang mu ghee pill soft capsule for improving immunity |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102579818B (en) | 2014-01-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101804166B (en) | Traditional Chinese medicine composition for treating dermatitis and eczema of infants | |
| CN103751633A (en) | Traditional Chinese medicinal composition for treating varicose vein of lower limb and preparation method thereof | |
| CN103690919A (en) | Medicine for treating piglet iron-deficiency anemia and preparation method of medicine | |
| CN102000164A (en) | Traditional Chinese medicine composition for treating psoriasis and preparation method thereof | |
| CN102772712A (en) | Traditional Chinese medicine composition for treating heat-toxicity, flourishing and blood stasis type diabetic foot | |
| CN102908474B (en) | Medicinal liquor for treating neurosis | |
| CN102579818B (en) | Traditional Tibetan medicine composition, preparation method thereof and application | |
| CN104721582A (en) | Medicine for treating hypomenorrhea due to deficiency of kidney and preparation method thereof | |
| CN102178781A (en) | Chinese medicine composition for treating scrotum eczema and preparation method thereof | |
| CN104258300A (en) | Traditional Chinese medicine preparation for treating apoplexy sequela due to vital energy deficiency and blood stasis and preparation method of traditional Chinese medicine preparation | |
| CN102805825B (en) | Drug for curing cutaneous pruritus and preparation method thereof | |
| CN104800610A (en) | Traditional Chinese medicine preparation for treating Parkinson's disease and preparation method thereof | |
| CN104906526A (en) | Chinese medicine preparation for premature ovarian failure and preparation method of Chinese medicine preparation | |
| CN104984049A (en) | Traditional Chinese medicine capsule for treating severe acute pancreatitis | |
| CN102091254A (en) | Traditional Chinese medicine composition for relieving swelling after cosmetic surgery and preparation method thereof | |
| CN106177736A (en) | A kind of alleviate gastrointestinal upset Chinese mugwort leaf health care tea causing constipation and preparation method thereof | |
| CN104940777A (en) | Electuary capable of treating liver-yang hyperactivity and spleen weakness type diarrhea during menstruation and preparation method thereof | |
| CN105267895A (en) | Medicine for treating bovine postpartum blood stasis type placenta retension and preparing method thereof | |
| CN104688855A (en) | Coptidis rhizome and donkey-hide glue composition for the treatment of chronic fatigue syndrome and application thereof | |
| CN104208366A (en) | Chinese medicinal drug for treating marrow depletion and kidney deficiency syndrome tinnitus cerebri | |
| CN104740396A (en) | Traditional Chinese medicine for treating kidney stones and preparation method of traditional Chinese medicine | |
| CN105288473A (en) | Traditional Chinese medicine composition for treating lupus erythematosus and application thereof | |
| CN104225506A (en) | Medicinal preparation for treating thrombocytopenia after chemotherapy | |
| CN103536883B (en) | The Chinese medicine for the treatment of heart kidney qi Yin bivacuity pattern of syndrome spleen fatiguing disease | |
| CN104474440A (en) | Pharmaceutical composition for treatment of nutritional anemia of piglets and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20151104 Address after: Lin Qionggang road Lhasa 851400 Tibet autonomous region economic and Technological Development Zone No. 15 Patentee after: TIBET GANLU TIBETAN MEDICINE CO., LTD. Address before: 850000, 23 hot road, Lhasa, Tibet Patentee before: Ci Wang |