CN102524776A - Soft capsule health food with auxiliary memory-improving function - Google Patents
Soft capsule health food with auxiliary memory-improving function Download PDFInfo
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Abstract
The invention relates to a soft capsule health food with an auxiliary memory-improving function. The product of the invention employs the following components as main raw materials: fish oil, taurine, zinc gluconate, beeswax, vitamin E, gelatin, glycerol, purified water, caramel and titanium dioxide. The method of the invention comprises the steps of mixing, dissolving gelatin, pelleting, shaping, drying, choosing pills and packaging to obtain the soft capsule. The product of the invention is specially prepared for children, has an auxiliary memory-improving function for children and a health care efficacy of supplementing nutrition for brain, and has the advantages of a high pertinence and an obvious effect of improving memory. In addition, the preparation method of the invention adopts a process which obviates a pill washing step, and the product of the invention has a stable quality and is a health food with good taste and convenience in carrying and eating.
Description
Technical field
The present invention relates to a kind of capsule health food containing, specifically is a kind of capsule health food containing with auxiliary improving memory function.
Background technology
Along with the continuous progress of the modern life, people's rhythm of life is accelerated, and life stress, operating pressure, learning pressure increase the weight of, human memory can receive influence in various degree and cause being losing one's memory, forgetful etc.
For children, elementary and middle school students particularly, the quality of memory function and its growth have comparatively confidential relation; Special more and more fierce along with social competition; It is entered a higher school, the pressure of lessons is also increasing, causes its outer burden heavier within the class period, the overlong time of requiring mental skill; Add the influence of factors such as not had enough sleep simultaneously, problem such as that increasing elementary and middle school students have occurred is absent-minded, decrease of memory.Therefore, children require mental skill and the improvement of memory function has received increasing concern.
Most of father and mother tend to through cultivating child's better learning custom; Or note the nutrition arrangement of scientific and reasonable diet aspect, or select some health products through the brain tonic and intelligence development class of authentications, check come to children require mental skill and memory is carried out auxiliary adjustment.Continuous progress and development along with growth in the living standard and scientific research; Health food with auxiliary improving memory function also day by day increases; But the health food that has auxiliary improving memory function in the market, with respect to other health care foods, its kind, negligible amounts; Through only 46 of the homemade health foods of State Food and Drug Administration approval, and some is that to be suitable for children inapplicable for the elderly.
Summary of the invention
The object of the invention is to provide a kind of children of aiming to develop, and can promote brain development, alleviates brain fag, to children have more significantly improve memory effect have capsule health food containing of auxiliary improving memory function and preparation method thereof.
For addressing the above problem; The technical scheme that the present invention adopted is: a kind of capsule health food containing with auxiliary improving memory function of the present invention; Form by content and capsule material; Wherein, content is made up of following raw material by weight percentage: fish oil 60-80%, taurine 15-30%, zinc gluconate 2.5-6%, beeswax 2-5%, vitamin E 0.3-1.5%.
Said capsule material is made up of following raw material by weight percentage: gelatin 37.5-41.56%, glycerine 16.3-23%, pure water 37.5-41.56%, burnt sugar coloring 0.2-2%, titanium dioxide 0.05-0.5%.
The mass ratio of the gelatin in the said capsule material, glycerine, pure water is: 1:0.4-0.6:1.
Said vitamin E is a natural VE.
A kind of capsule health food containing of the present invention with auxiliary improving memory function, its preparation method comprises following steps:
(1) takes by weighing by weight percentage: after fish oil 60-80%, taurine 15-30%, zinc gluconate 2.5-6%, beeswax 2-5%, vitamin E 0.3-1.5% mix, be prepared into content;
(2) take by weighing by weight percentage: gelatin 37.5-41.56%, glycerine 16.3-23%, pure water 37.5-41.56%, burnt sugar coloring 0.2-2%, titanium dioxide 0.05-0.5% stir, colloidal sol preparation encystation material;
(3) adopt disposable ball prepared: above-mentioned steps (1) is made content and step (2) makes the capsule material; Employing can be controlled the encapsulating machine of flow of lubrication; Through pelleting, typing, drying, select ball, packing, make a kind of capsule health food containing with auxiliary improving memory function.
Vitamin E is a natural VE described in said preparation method's the preparation process (1).
The present invention with respect to the beneficial effect of prior art is:
(1) DHA (DHA) is the main component of aliphatic acid in the human brain, can strengthen and improve brain function, improves intelligence; Be essential fatty acid, children replenish DHA, and the contact between the nerve cell is strengthened; The transmission of information is unobstructed, thereby improves memory, therefore; A kind of capsule health food containing with auxiliary improving memory function of the present invention adopts the fish oil contain DHA as one of primary raw material of product in its prescription; Taurine is a kind of micromolecular sulfur-bearing beta-amino acids; Research has confirmed that taurine is not only one of the abundantest free amino acid of in-vivo content, and has the important physical function in vivo, suitably supplementation of taurine; Can strengthen the activity of enzyme in the nerve cell, be of value to and improve memory; Moreover zinc is the indispensable trace element of human body, and zinc supplementation can promote child's torso and intelligence development.A kind of capsule health food containing with auxiliary improving memory function of the present invention has thus adopted fish oil, taurine, these three kinds raw materials with improvement memory of zinc gluconate to unite use, more can bring into play it improves memory to children function;
(2) a kind of capsule health food containing of the present invention with auxiliary improving memory function, disposable ball technology has been adopted in its preparation, owing to adopted the encapsulating machine that can control flow of lubrication; In producing the soft capsule process, can control flow rate of lubricating oil, making in process of production, only there is a spot of lubricating oil on the soft capsule surface; Finished product soft capsule any surface finish after the rotating cage typing; No greasy, therefore need not wash ball in process of production to soft capsule, guarantee constant product quality;
(3) a kind of capsule health food containing with auxiliary improving memory function of the present invention according to Material Characteristics, is chosen as soft capsule with product forms; Have good isolation light, oxygen function and good visual effect, and mouthfeel is good, is prone to swallow; Be prone to false proof; Safe to carry, good looking appearance, characteristics such as easy to use when being suitable for daily house and using, are more suitable for people to be away on a vacation, to use when travelling;
(4) in addition; A kind of capsule health food containing with auxiliary improving memory function according to the invention use as suspending agent with beeswax in its prescription, but soft capsule strengthens the uniformity of content; Make the good fluidity of soft capsule content, guarantee the stable dose of soft capsule.
The specific embodiment
Through embodiment the present invention is explained further details below, these embodiment only are used for explaining the present invention, do not limit the scope of the invention.
Embodiment 1Adopt following raw materials according and preparation method to prepare a kind of capsule health food containing with auxiliary improving memory function: 1, the content raw material is formed (by weight percentage): fish oil 60%, taurine 30%, zinc gluconate 5%, beeswax 4%, natural VE 1%; Capsule material raw material is formed (weight percent meter): gelatin 37.5%, glycerine 22.5%, pure water 37.5%, burnt sugar coloring 2.0%, titanium dioxide 0.5%, the gelatin in the capsule material raw material, glycerine, pure water are chosen by the mass ratio of 1:0.6:1.
2, prepare according to following steps:
(1) get the fish oil 60%, taurine 30%, zinc gluconate 5%, beeswax 4%, the natural VE 1% that take by weighing by weight percentage and mix after, be prepared into content;
(2) get gelatin 37.5%, glycerine 22.5%, pure water 37.5%, burnt sugar coloring 2.0%, the titanium dioxide 0.5% that takes by weighing by weight percentage, stir, colloidal sol, preparation encystation material;
(3) adopt disposable ball prepared: will make content and make the capsule material, employing can be controlled the encapsulating machine of flow of lubrication, through pelleting, typing, drying, select ball, packing, makes a kind of capsule health food containing with auxiliary improving memory function.
Embodiment 2Adopt following raw materials according and preparation method to prepare a kind of capsule health food containing with auxiliary improving memory function: 1, the content raw material is formed (by weight percentage): fish oil 65%, taurine 25%, zinc gluconate 6%, beeswax 2.5%, natural VE 1.5%; Capsule material raw material is formed (weight percent meter): gelatin 40.75%, glycerine 16.3%, pure water 40.75%, burnt sugar coloring 1.8%, titanium dioxide 0.4%, the gelatin in the capsule material raw material, glycerine, pure water are chosen by the mass ratio of 1:0.4:1.
2, prepare according to following steps:
(1) get the fish oil 65%, taurine 25%, zinc gluconate 6%, beeswax 2.5%, the natural VE 1.5% that take by weighing by weight percentage and mix after, be prepared into content;
(2) get gelatin 40.75%, glycerine 16.3%, pure water 40.75%, burnt sugar coloring 1.8%, the titanium dioxide 0.4% that takes by weighing by weight percentage, stir, colloidal sol, preparation encystation material;
(3) adopt disposable ball prepared: will make content and make the capsule material, employing can be controlled the encapsulating machine of flow of lubrication, through pelleting, typing, drying, select ball, packing, makes a kind of capsule health food containing with auxiliary improving memory function.
Embodiment 3Adopt following raw materials according and preparation method to prepare a kind of capsule health food containing with auxiliary improving memory function:
1, the content raw material is formed (by weight percentage): fish oil 62%, taurine 28%, zinc gluconate 5.5%, beeswax 3.5%, natural VE 1%; Capsule material raw material is formed (weight percent meter): gelatin 38.5%, glycerine 21.18%, pure water 38.5%, burnt sugar coloring 1.6%, titanium dioxide 0.22%, the gelatin in the capsule material raw material, glycerine, pure water are chosen by the mass ratio of 1:0.55:1.
2, prepare according to following steps:
(1) get the fish oil 62%, taurine 28%, zinc gluconate 5.5%, beeswax 3.5%, the natural VE 1% that take by weighing by weight percentage and mix after, be prepared into content;
(2) get gelatin 38.5%, glycerine 21.18%, pure water 38.5%, burnt sugar coloring 1.6%, the titanium dioxide 0.22% that takes by weighing by weight percentage, stir, colloidal sol, preparation encystation material;
(3) adopt disposable ball prepared: will make content and make the capsule material, employing can be controlled the encapsulating machine of flow of lubrication, through pelleting, typing, drying, select ball, packing, makes a kind of capsule health food containing with auxiliary improving memory function.
Embodiment 4Adopt following raw materials according and preparation method to prepare a kind of capsule health food containing with auxiliary improving memory function: 1, the content raw material is formed (by weight percentage): fish oil 67%, taurine 27%, zinc gluconate 3.5%, beeswax 2%, natural VE 0.5%; Capsule material raw material is formed (weight percent meter): gelatin 39.5%, glycerine 19.75%, pure water 39.5%, burnt sugar coloring 1.2%, titanium dioxide 0.05%, the gelatin in the capsule material raw material, glycerine, pure water are chosen by the mass ratio of 1:0.5:1.
2, prepare according to following steps:
(1) get the fish oil 67%, taurine 27%, zinc gluconate 3.5%, beeswax 2%, the natural VE 0.5% that take by weighing by weight percentage and mix after, be prepared into content;
(2) get gelatin 39.5%, glycerine 19.75%, pure water 39.5%, burnt sugar coloring 1.2%, the titanium dioxide 0.05% that takes by weighing by weight percentage, stir, colloidal sol, preparation encystation material;
(3) adopt disposable ball prepared: will make content and make the capsule material, employing can be controlled the encapsulating machine of flow of lubrication, through pelleting, typing, drying, select ball, packing, makes a kind of capsule health food containing with auxiliary improving memory function.
Embodiment 5Adopt following raw materials according and preparation method to prepare a kind of capsule health food containing with auxiliary improving memory function: 1, the content raw material is formed (by weight percentage): fish oil 70%, taurine 22%, zinc gluconate 4.5%, beeswax 3.2%, natural VE 0.3%; Capsule material raw material is formed (weight percent meter): gelatin 40.3%, glycerine 18.14%, pure water 40.3%, burnt sugar coloring 0.82%, titanium dioxide 0.44%, the gelatin in the capsule material raw material, glycerine, pure water are chosen by the mass ratio of 1:0.45:1.
2, prepare according to following steps:
(1) gets the fish oil 70% that takes by weighing by weight percentage, taurine 22%, zinc gluconate 4.5%, beeswax 3.2%, natural VE 0.3% at 25 ℃, mix under the condition of humidity 55%, be prepared into content;
(2) get gelatin 40.3%, glycerine 18.14%, pure water 40.3%, burnt sugar coloring 0.82%, the titanium dioxide 0.44% that takes by weighing by weight percentage, stir, colloidal sol, preparation encystation material;
(3) adopt disposable ball prepared: will make content and make the capsule material, employing can be controlled the encapsulating machine of flow of lubrication, through pelleting, typing, drying, select ball, packing, makes a kind of capsule health food containing with auxiliary improving memory function.
Embodiment 6Adopt following raw materials according and preparation method to prepare a kind of capsule health food containing with auxiliary improving memory function: 1, the content raw material is formed (by weight percentage): fish oil 75%, taurine 17%, zinc gluconate 3%, beeswax .4.2%, natural VE 0.8%; Capsule material raw material is formed (weight percent meter): gelatin 38.33%, glycerine 23%, pure water 38.33%, burnt sugar coloring 0.24%, titanium dioxide 0.1%, the gelatin in the capsule material raw material, glycerine, pure water are chosen by the mass ratio of 1:0.6:1.
2, prepare according to following steps:
(1) get the fish oil 75%, taurine 17%, zinc gluconate 3%, beeswax .4.2%, the natural VE 0.8% that take by weighing by weight percentage and mix after, be prepared into content;
(2) get gelatin 38.33%, glycerine 23%, pure water 38.33%, burnt sugar coloring 0.24%, the titanium dioxide 0.1% that takes by weighing by weight percentage, stir, colloidal sol, preparation encystation material;
(3) adopt disposable ball prepared: will make content and make the capsule material, employing can be controlled the encapsulating machine of flow of lubrication, through pelleting, typing, drying, select ball, packing, makes a kind of capsule health food containing with auxiliary improving memory function.
Embodiment 7Adopt following raw materials according and preparation method to prepare a kind of capsule health food containing with auxiliary improving memory function:
1, the content raw material is formed (by weight percentage): fish oil 80%, taurine 15%, zinc gluconate 2.5%, beeswax 2%, natural VE 0.5%; Capsule material raw material is formed (weight percent meter): gelatin 41.56%, glycerine 16.62%, pure water 41.56%, burnt sugar coloring 0.2%, titanium dioxide 0.06%, the gelatin in the capsule material raw material, glycerine, pure water are chosen by the mass ratio of 1:0.4:1.
2, prepare according to following steps:
(1) get the fish oil 80%, taurine 15%, zinc gluconate 2.5%, beeswax 2%, the natural VE 0.5% that take by weighing by weight percentage and mix after, be prepared into content;
(2) get gelatin 41.56%, glycerine 16.62%, pure water 41.56%, burnt sugar coloring 0.2%, the titanium dioxide 0.06% that takes by weighing by weight percentage, stir, colloidal sol, preparation encystation material;
(3) adopt disposable ball prepared: will make content and make the capsule material, employing can be controlled the encapsulating machine of flow of lubrication, through pelleting, typing, drying, select ball, packing, makes a kind of capsule health food containing with auxiliary improving memory function.
Embodiment 8Adopt following raw materials according and preparation method to prepare a kind of capsule health food containing with auxiliary improving memory function: the content raw material is formed (by weight percentage): fish oil 72%, taurine 17.8%, zinc gluconate 4%, beeswax 5%, natural VE 1.2%; Capsule material raw material is formed (weight percent meter): gelatin 39.8%, glycerine 19.9%, pure water 39.8%, burnt sugar coloring 0.4%, titanium dioxide 0.1%, the gelatin in the capsule material raw material, glycerine, pure water are chosen by the mass ratio of 1:0.5:1.
Prepare according to following steps:
(1) get the fish oil 72%, taurine 17.8%, zinc gluconate 4%, beeswax 5%, the natural VE 1.2% that take by weighing by weight percentage and mix after, be prepared into content;
(2) get gelatin 39.8%, glycerine 19.9%, pure water 39.8%, burnt sugar coloring 0.4%, the titanium dioxide 0.1% that takes by weighing by weight percentage, stir, colloidal sol, preparation encystation material;
(3) adopt disposable ball prepared: will make content and make the capsule material, employing can be controlled the encapsulating machine of flow of lubrication, through pelleting, typing, drying, select ball, packing, makes a kind of capsule health food containing with auxiliary improving memory function.
Experimental exampleBelow further specify the present invention through test: adopt the embodiment of the invention 5 prepared soft capsule health products to carry out the auxiliary improving memory function human feeding trial of product.
1 test material and method.
1.1 sample: adopt the prepared soft capsule health product of the embodiment of the invention 5, No. 1, No. 2, the two is basically identical on packing, outward appearance, color and luster and mouthfeel, and one of them is a soft capsule health product sample of the present invention, and another is a placebo.Human oral RD every day 1 time, each 3.
1.2 the experimenter selects
1.2.1 the standard of including in: the experimenter is from middle school, Hengnan County, Hengyang City; Healthy, no dysnoesia, informed consent; Be ready to give one's cooperation; The healthy students of age between 11 to 14 years old do not accepted similarly test (memory quotient, IQ test), do not take medicine or the health food relevant with improving memory in 1 year.
1.2.2 exclusion standard: obvious impediment person is arranged, influential hearing, language performance and amentia have obvious spirit, sleep and life style to reach the cooperation gastrointestinal disease patient unusually; Take the medicine relevant in a short time, have influence on judgement person as a result with being tried function; Do not meet the standard of including in,, can't judge effect or data not umbra sound effect or security judgement person not by the edible given the test agent of regulation.
1.3 experimental design and grouping: adopt contrast, double blinding, method for designing at random.From elementary middle school, extract two classes of the same grade through the method for cluster at random, the colony that living environment is close carries out before the clothes appearance testing first time; Just line up by memory quotient; By ordering is strange, even number divides two groups, is test group randomly drawing one group, another group is control group.
1.4 test method: from beginning on 09 27th, 2008, will meet the standard of including in and guarantee the volunteer of compatibility test, and be divided at random and receive examination group and control group.Receive examination group and control group to take the soft capsule health product sample or the placebo of this test, took continuously 40 days by RD.Duration of test does not change original eating habit, normal diet.
1.5 main equipment and method of testing and environment:
1.5.1 test equipment: record has the memory of sensing and the instruction of associative learning and the tape of stimulus; Free recall each 15 in two groups in image picture of picture information, image, totally 30 (dividing first, second two covers); Random shape is re-recognized picture, is equipped with to appear with 20 in goal stimulus picture for the first time, and being equipped with to appear when re-recognizing for the second time with goal stimulus stimulates each 20 in picture with sneaking into, and totally 40, adds up to 60 pictures (branch first, second two covers); Picture is recalled in the contact of portrait characteristics, is used black and white for the first time fully and delineates people's face as 6, and the people's face that appears when recalling fully is as 6, and both contents are identical, and order is different, amounts to 12; Every portrait picture back side indicates characteristics (branch first, second two covers) such as the surname, occupation, hobby of this portrait.Recorder, stopwatch, record-paper.
1.5.2 method of testing and environment:
1.5.2.1 method of testing: forward and backward twice test of each experimenter reduces systematic error by same main examiner's testing.The test time point: each experimenter is forward and backward to be determined at same time point twice and to carry out, and avoids the influence of biological rhythm.When testing for the second time, the main examiner does not see the grouping list, blind method test.
1.5.2.2 the environmental condition during test: the personnel by receiving specialized training test; Testing location is selected in a quiet room to carry out.Except that experimenter and main examiner, avoided other people on the scene as far as possible; This scale has three branch tests relevant with vision, and indoor light can guarantee to see clearly Chu stimulates picture; Get rid of because of hearing or dysphotia as far as possible and influence the memory achievement; The state of mind when close attention experimenter is tested during test, test needs normal in experimenter's mood, does not oppose to accept test, carries out under the situation that notice is relatively concentrated; Whether whether whether the experimenter is tired, and whether notice is concentrated, cooperate, nervous to test, and whether confident the grade all is recorded on the homepage of record-paper; Same experimenter's test is once finished; When comparing the subtest achievement, note what whether different subtests carried out under the same spirit state with the age scale branch.Insert in the original subitem after the original branch check of each item subtest achievement is errorless.
1.5.2.3 data processing method: will record branch (original branch) and be converted into scale score; The scale score of each item subtest between comparing two groups; Calculate total scale score; The memory quotient of looking into is the difference between two groups relatively, and the contrast dual mode carries out statistical analysis between employing own control and group, eliminates the influence of transfer learning.
2 observation index: each measures once each item observation index when test-meal on-test and end.
2.1 safety indexes
2.1.1 ordinary circumstance: perquisition experimenter health status before the test, situation such as understanding experimenter's spirit, sleep, diet, stool and urine.Carry out cardiopulmonary auscultation, liver palpation of spleen, and measure body weight, blood pressure, heart rate.
2.1.2 routine blood test: red blood cell count(RBC), white blood cell count(WBC), content of hemoglobin mensuration etc.
2.1.3 routine urinalysis: pH value, leucocyte etc.
2.1.4 stool for routine: worm's ovum inspection etc.
2.1.5 bad reaction is observed
2.2 effect index: use the test of Clinical Memory scale, look into scale score with the original branch of each subtest after the test; Sensing memory, associative learning, image are freed recall, random shape is re-recognized, the contact of portrait characteristics is recalled.Each subtest scale score addition gets total scale score, looks into memory quotient with total scale score.
3 data statistics: this test data is a measurement data, can analyze with the t check two groups of each subtest scale scores and memory quotient.Own control can adopt paired t-test; The parallel t check of relatively adopting two sample means between group, the latter need carry out homogeneity test of variance, and the data of Non-Gaussian Distribution or heterogeneity of variance are carried out suitable variable conversion; Wait to satisfy normal state or variance neat after, carry out the t check with data converted; If translation data still can not satisfy the neat requirement of normal state variance, use t check or rank test instead; But the data of the coefficient of variation too big (like CV>50%) is used rank test.Add up with SPSS, INSTAT statistical software.
4 results judge: under the prerequisite that two groups of memory quotient are balanced before test; The memory quotient of test-meal group is higher than control group after the test-meal; And difference has conspicuousness; Memory quotient after the test-meal group test simultaneously is higher than the memory quotient before its test, and difference has conspicuousness, can judge that this given the test agent has the effect of auxiliary improving memory function.
5 results: double-blind study is observed and is finished to make known: take No. 1 person and be this test soft capsule health product sample, take No. 2 persons and be placebo.
5.1 ordinary circumstance: initial trial crowd's test group 53 examples; Control group 53 examples; After test in 40 days, test group has 0 routine experimenter to receive test product or can't be screened out by determine effect because of being interrupted to take, and control group has 0 routine experimenter to receive test product or can't be screened out by determine effect because of being interrupted to take.Last efficiency test crowd test group 53 examples, control group 53 examples.Control group age 1 l. 96 ± 0.59 years old, 11.98 ± 0.57 years old test group age; Control group: man/woman is 32/21, test group: man/woman is 31/22.Equal Non Apparent Abnormality such as experimenter's mental status, diet situation, sleep quality and mental activity before and after the test.
5.2 security is observed
5.2.1 cardiopulmonary auscultation, liver palpation of spleen, body weight, heart rate, routine blood test, routine urinalysis, stool routine examination: see table l.The edible examination before and after the thing; Test-meal group and control group body weight, heart rate, routine blood test, routine urinalysis, stool routine examination etc. are not all seen obvious abnormal change; Cardiopulmonary auscultation, liver palpation of spleen no abnormality seen point out this test soft capsule health product sample that body health is not had obvious damage.
Cardiopulmonary auscultation before and after this test of table 1 soft capsule health product sample human feeding trial; The liver palpation of spleen; Body weight; Heart rate; Routine blood test; Routine urinalysis; Stool routine examination testing result (
± s)
5.2.2 do not see obvious adverse reaction during the test-meal
5.3 this test soft capsule health product sample is to the influence of human body memory effect index
This test of table 2 soft capsule health product sample is to pointing to the influence (
± s) of memory scale score
| ? | Number | Before the test | After the test | P value (self) |
| Control group | 53 | 14.55±5.33 | 18.55±7.56 | 0.0021 |
| Test group | 53 | 14.02±5.55 | 20.87±5.05 | 0.0000 |
| P value (between group) | —— | 0.6171 | 0.0660 | —— |
Visible by table 2, the sensing memory scale score of test group compares with control group before the clothes appearance, and difference does not have conspicuousness (P>0.05); Relatively, difference has conspicuousness (P < 0.05) before the sensing memory scale score of clothes appearance back test group and self the clothes appearance, compares with a clothes appearance back control group, and difference does not have conspicuousness (P>0.05).
This test of table 3 soft capsule health product sample to the influence of associative learning scale score (± s)
| ? | Number | Before the test | After the test | P value (self) |
| Control group | 53 | 15.66±5.81 | 19.85±7.79 | 0.0022 |
| Test group | 53 | 15.94±5.73 | 23.74±5.29 | 0.0000 |
| P value (between group) | —— | 0.8032 | 0.0033 | —— |
Visible by table 3, the associative learning scale score of test group compares with control group before the clothes appearance, and difference does not have conspicuousness (P>0.05); Relatively, difference has conspicuousness (P < 0.05) before the associative learning scale score of clothes appearance back test group and self the clothes appearance, compares with a clothes appearance back control group, and difference has conspicuousness (P < 0.05).
This test of table 4 soft capsule health product sample is to the free recall influence (
± s) of scale score of image
| ? | Number | Before the test | After the test | P value (self) |
| Control group | 53 | 15.81±5.57 | 16.11±5.47 | 0.7802 |
| Test group | 53 | 16.26±4.98 | 16.85±5.16 | 0.5505 |
| P value (between group) | —— | 0.6620 | 0.4753 | —— |
Visible by table 4, the image of the test group scale score of freeing recall compares with control group before the clothes appearance, and difference does not have conspicuousness (P>0.05); The image of clothes appearance back test group is freed recall before scale score and self the clothes appearance and a clothes appearance back control group compares, and difference does not all have conspicuousness (P>0.05).
This test of table 5 soft capsule health product sample is re-recognized the influence (
± s) of scale score to random shape
| ? | Number | Before the test | After the test | P value (self) |
| Control group | 53 | 18.51±8.35 | 19.53±7.31 | 0.5049 |
| Test group | 53 | 18.49±8.92 | 21.30±6.17 | 0.0621 |
| P value (between group) | —— | 0.9905 | 0.1809 | —— |
Visible by table 5, the random shape of test group is re-recognized scale score and is compared with control group before the clothes appearance, and difference does not have conspicuousness (P>0.05); The random shape of clothes appearance back test group is re-recognized before scale score and self the clothes appearance and a clothes appearance back control group compares, and difference does not all have conspicuousness (P>0.05).
This test of table 6 soft capsule health product sample is recognized the influence (
± s) of scale score to portrait characteristics contact memory
| ? | Number | Before the test | After the test | P value (self) |
| Control group | 53 | 11.11±6.51 | 13.64±5.67 | 0.0352 |
| Test group | 53 | 11.06±6.47 | 16.47±5.09 | 0.0000 |
| P value (between group) | —— | 0.9684 | 0.0080 | —— |
Visible by table 6, the portrait characteristics contact of test group is recalled scale score and is compared with control group before the clothes appearance, and difference does not have conspicuousness (P>0.05); The portrait characteristics contact of clothes appearance back test group is recalled before scale score and self the clothes appearance and a clothes appearance back control group compares, and difference all has conspicuousness (P < 0.05).
This test of table 7 soft capsule health product sample is to the influence (
± s) of memory quotient
| ? | Number | Before the test | After the test | P value (self) |
| Control group | 53 | 70.26±15.78 | 78.72±16.57 | 0.0083 |
| Test group | 53 | 70.30±16.03 | 88.64±14.56 | 0.0000 |
| P value (between group) | -- | 0.9897 | 0.0014 | -- |
Visible by table 7, the memory quotient of test group compares with control group before the clothes appearance, and difference does not have conspicuousness (P>0.05); The memory quotient of clothes appearance back test group is significantly higher than control group (P < 0.05); Before memory quotient after the test group clothes appearance is significantly higher than clothes appearance (P 0.05).
6 brief summaries:
Human feeding trial is the result show; The experimenter takes this test soft capsule health product sample after 40 days continuously; Test group is pointed to and to be compared before scale score and memory quotient and clothes appearance are recalled in memory, associative learning, the contact of portrait characteristics, all be higher than test before, and difference has conspicuousness (P < 0.05); Scale score is recalled in the contact of test group associative learning, portrait characteristics and memory quotient all is higher than control group, and difference has conspicuousness (P < 0.05).According to " health food check and assessment technique standard " (version in 2003) evaluation criterion, point out the effect that sample has auxiliary improvement human body memory function of this test soft capsule health product.
Claims (6)
1. capsule health food containing with auxiliary improving memory function; Be made up of content and capsule material, it is characterized in that: said content is made up of following raw material by weight percentage: fish oil 60-80%, taurine 15-30%, zinc gluconate 2.5-6%, beeswax 2-5%, vitamin E 0.3-1.5%.
2. the capsule health food containing with auxiliary improving memory function according to claim 1 is characterized in that: said capsule material is made up of following raw material by weight percentage: gelatin 37.5-41.56%, glycerine 16.3-23%, pure water 37.5-41.56%, burnt sugar coloring 0.2-2%, titanium dioxide 0.05-0.5%.
3. the capsule health food containing with auxiliary improving memory function according to claim 1 and 2 is characterized in that: the mass ratio of the gelatin in the said capsule material, glycerine, pure water is: 1:0.4-0.6:1.
4. according to each described capsule health food containing with auxiliary improving memory function among the claim 1-3, it is characterized in that: said vitamin E is a natural VE.
5. preparation method with capsule health food containing of auxiliary improving memory function as claimed in claim 1, it is characterized in that: this method comprises following steps:
Take by weighing by weight percentage: after fish oil 60-80%, taurine 15-30%, zinc gluconate 2.5-6%, beeswax 2-5%, vitamin E 0.3-1.5% mix, be prepared into content;
Take by weighing by weight percentage: gelatin 37.5-41.56%, glycerine 16.3-23%, pure water 37.5-41.56%, burnt sugar coloring 0.2-2%, titanium dioxide 0.05-0.5% stir, colloidal sol preparation encystation material;
Adopt disposable ball prepared: above-mentioned steps (1) is made content and step (2) makes the capsule material; Employing can be controlled the encapsulating machine of flow of lubrication; Through pelleting, typing, drying, select ball, packing, make a kind of capsule health food containing with auxiliary improving memory function.
6. the preparation method with capsule health food containing of auxiliary improving memory function according to claim 5 is characterized in that: vitamin E is a natural VE in the said preparation process (1).
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| CN2011104204911A CN102524776A (en) | 2011-12-15 | 2011-12-15 | Soft capsule health food with auxiliary memory-improving function |
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| CN2011104204911A CN102524776A (en) | 2011-12-15 | 2011-12-15 | Soft capsule health food with auxiliary memory-improving function |
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| CN102524776A true CN102524776A (en) | 2012-07-04 |
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| CN2011104204911A Pending CN102524776A (en) | 2011-12-15 | 2011-12-15 | Soft capsule health food with auxiliary memory-improving function |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103238840A (en) * | 2013-05-16 | 2013-08-14 | 汤臣倍健股份有限公司 | Ginkgo biloba extract and fish oil soft capsule and preparation method thereof |
| CN103349291A (en) * | 2013-06-24 | 2013-10-16 | 汤臣倍健股份有限公司 | Composition and capsule with good stability and function of improving faculty of memory and preparation method thereof |
| CN104147081A (en) * | 2014-08-20 | 2014-11-19 | 哈尔滨顺亿堂医药生物科技开发有限公司 | Blueberry lutein soft capsule for improving eyesight and manufacturing method thereof |
| CN104189014A (en) * | 2014-09-03 | 2014-12-10 | 汤臣倍健股份有限公司 | Soybean phospholipid soft capsule and preparation method thereof |
| CN106692166A (en) * | 2015-11-18 | 2017-05-24 | 珠海宝德润生健康科技有限公司 | Composition with memory improving function, and preparation method thereof |
| CN114601166A (en) * | 2022-03-02 | 2022-06-10 | 江苏盛世康禾生物技术有限公司 | Health food for strengthening brain and improving memory and preparation method thereof |
| CN116458644A (en) * | 2022-01-12 | 2023-07-21 | 国珍健康科技（北京）有限公司 | Health food for improving memory and preparation method thereof |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103238840A (en) * | 2013-05-16 | 2013-08-14 | 汤臣倍健股份有限公司 | Ginkgo biloba extract and fish oil soft capsule and preparation method thereof |
| CN103238840B (en) * | 2013-05-16 | 2014-10-29 | 汤臣倍健股份有限公司 | Ginkgo biloba extract and fish oil soft capsule and preparation method thereof |
| CN103349291A (en) * | 2013-06-24 | 2013-10-16 | 汤臣倍健股份有限公司 | Composition and capsule with good stability and function of improving faculty of memory and preparation method thereof |
| CN103349291B (en) * | 2013-06-24 | 2015-05-27 | 汤臣倍健股份有限公司 | Composition and capsule with good stability and function of improving faculty of memory and preparation method thereof |
| CN104147081A (en) * | 2014-08-20 | 2014-11-19 | 哈尔滨顺亿堂医药生物科技开发有限公司 | Blueberry lutein soft capsule for improving eyesight and manufacturing method thereof |
| CN104189014A (en) * | 2014-09-03 | 2014-12-10 | 汤臣倍健股份有限公司 | Soybean phospholipid soft capsule and preparation method thereof |
| CN104189014B (en) * | 2014-09-03 | 2018-01-02 | 汤臣倍健股份有限公司 | A kind of soybean lecithin soft capsule and preparation method thereof |
| CN106692166A (en) * | 2015-11-18 | 2017-05-24 | 珠海宝德润生健康科技有限公司 | Composition with memory improving function, and preparation method thereof |
| CN116458644A (en) * | 2022-01-12 | 2023-07-21 | 国珍健康科技（北京）有限公司 | Health food for improving memory and preparation method thereof |
| CN114601166A (en) * | 2022-03-02 | 2022-06-10 | 江苏盛世康禾生物技术有限公司 | Health food for strengthening brain and improving memory and preparation method thereof |
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