CN102512609A - Essential oil with anti-inflammatory, analgesic, cooling, itching-relieving and mosquito-dispelling functions - Google Patents
Essential oil with anti-inflammatory, analgesic, cooling, itching-relieving and mosquito-dispelling functions Download PDFInfo
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- CN102512609A CN102512609A CN2011104592550A CN201110459255A CN102512609A CN 102512609 A CN102512609 A CN 102512609A CN 2011104592550 A CN2011104592550 A CN 2011104592550A CN 201110459255 A CN201110459255 A CN 201110459255A CN 102512609 A CN102512609 A CN 102512609A
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Abstract
The invention relates to an essential oil with anti-inflammatory, analgesic, cooling, itching-relieving and mosquito-dispelling functions, in particular to an essential oil formulation with an improved mosquito bite-preventing function. Based on the formulation of the traditional wind medicated oil, the essential oil uses three plant medicated oils such as citionella oil, patchouli oil and cassia oil, and the essential oil comprises 20-35% of menthol, 13-39% of wintergreen oil, 1-5% of camphor oil, 1-5% of eucalyptus oil, 1-6% of Ocimum gratissimum oil, 3-15% of citionella oil, 1-5% of patchouli oil, 1-5% of cassia oil, a proper amount of paraffin oil, a proper amount of smell-rectifying agent and a proper amount of coloring agent. The essential oil can be prepared into liniment, spray and lotion; and the mosquito-dispelling and mosquito-avoiding effective time is obviously longer than that of the traditional wind medicated oil. The invention discloses a formulation and a preparation method of the essential oil.
Description
Technical field
The present invention relates to a kind of quintessence oil, relate in particular to a kind of quintessence oil prescription that strengthens control mosquito bite effect with anti-inflammatory analgesic, refrigerant antipruritic and function of driving mosquitoes.
Background technology
In daily life; Standing in a lot of families medicine-chest have some medicines oily, and it is red and swollen and uncomfortable that be used for mosquito bite, traumatic injury and being under the weather etc. causes, common product has safety oil, tiger balm, white flower oil and essential balm etc.; These medicine oil; The effect of the malaise symptoms that the elimination mosquito bite produces is more definite, and summer, the refrigerant effect of driving away summer heat was also more powerful, but lacks anophelifuge and anophelifuge effect.Wherein essential balm is a kind of have antiinflammatory, analgesia; The conventional Chinese medicine preparation refrigerant, that itching-relieving efficacies is good; The present invention is the basis with the prescription of traditional essential balm; The plant extract crude oil that adopt increase citronella oil, patchouli oil and Oleum Cinnamomi three flavor plants essential oils more, can significantly strengthen the anophelifuge effect of product.
Citronella oil, patchouli oil and Oleum Cinnamomi are conventional Chinese medicine plant extract medicine oil; Wherein citronella oil is claimed Rhizoma et radix valerianae oil again; Herb by Herba Cymbopogonis Citrari gets through steam distillation. weak yellow liquid. and fragrance is suitable; Main component is citronellal, geraniol and citronellol, mainly as insecticide, anophelifuge and soap perfume, has good control mosquito bite effect.Patchouli oil is the quintessence oil that Labiatae thorn stamen grass platymiscium Herba Pogostemonis obtains through steam distillation; Inhibited to common pathogenic entero becteria, tens kinds of skin pathogenic bacterium and various plants pathogen; Bai Shi plasmodium to parasitizing human body also has the poisoning potentiation; Research shows that it also has stronger prophylactic-therapeutic effect to the poisoning of lineae ablicantes albopictus larvae, adult mosquito smoked kill and repellent etc., and main effectively active component is patchouli alcohol, Pogostone, pinene, patchoulene, caryophyllene etc.Cassia oil is claimed Oleum Cinnamomi, Cortex cinnamomi japonici (Ramulus Cinnamomi) wet goods again, is the volatile oil that the cinnamomic dry branch of canella, skin, leaf or Herb obtain through steam distillation, and the master contains cinnamic aldehyde, the effect that have wind dispelling, is good for the stomach.Three and Mentholum, wintergreen oil, Oleum Camphora, Oleum Eucalypti, Ocimum Basilicum wet goods compatibility use, and can significantly improve the mosquito-proof effect of anophelifuge of product.
Quintessence oil of the present invention is formed (each components based on weight percentage) by following component
Liquid paraffin during the present invention forms can be selected the liquid Paraffin of different viscosities and relative density for use mainly as substrate, is used to regulate zones of different crowd skin feel.Mineral drug oil such as 0.830～0.890 the liquid Paraffin that preferred relative density scope is, light liquid petrolatum.
Flavoring agent can select for use the essence and the specific fragrance of the various odor types of natural extract or synthetic can do the plant extract oil of rectifying smelly usefulness; Flavoring agent promptly can use separately; Can use also not that the essence of odor type of the same race mixes use according to a certain percentage, be preferably the oil soluble perfume of independent use rose scent.
Coloring agent can be selected the pigment of the various models of natural extract or synthetic for use; Promptly can use separately; Can use also not that the pigment of model of the same race mixes use according to a certain percentage, the present invention process the color of quintessence oil or be preferably faint yellow to yellow, yellow green; Light green is to green, more preferably light green.The coloring agent that uses is preferably the oil-soluble chlorophyll.
Quintessence oil of the present invention is processed through following method
Method for making 1: get thin what brain, Oleum Camphora, it is an amount of to add liquid Paraffin, adds Oleum Eucalypti, methyl salicylate, eugenol, citronella oil, patchouli oil, cassia oil again, flavoring agent is an amount of, coloring agent is an amount of; Add liquid paraffin, mixing left standstill 24 hours; Get clear liquor, packing promptly gets.
Method for making 2: get thin what brain, Oleum Camphora, it is an amount of to add liquid Paraffin, add Oleum Eucalypti, methyl salicylate, eugenol, citronella oil, patchouli oil, cassia oil again, rectify smelly an amount of, coloring agent is an amount of, adds liquid paraffin, mixing filters, and gets filtrating, packing promptly gets.
Quintessence oil of the present invention can be processed liniment, spray, the varnish on the pharmaceutics meaning.
The specific embodiment
Below further specify the present invention through embodiment:
Embodiment 1
Get thin what brain, Oleum Camphora, it is an amount of to add liquid Paraffin, adds Oleum Eucalypti, wintergreen oil, Oleum Ocimi Gratissimi, citronella oil, patchouli oil, cassia oil again, essence is an amount of, chlorophyll is an amount of; Add the residue liquid Paraffin, mixing left standstill 24 hours; Get clear liquor, packing promptly gets.
Embodiment 2
Get thin what brain, Camphora, it is an amount of to add light liquid petrolatum, adds Oleum Eucalypti, methyl salicylate, Oleum Ocimi Gratissimi, citronella oil, patchouli oil, cassia oil again, essence is an amount of, chlorophyll is an amount of; Add the residue light liquid petrolatum, mixing filters; Get filtrating, packing promptly gets.
Embodiment 3
Get thin what brain, Oleum Camphora, it is an amount of to add liquid Paraffin, adds Oleum Eucalypti, methyl salicylate, Oleum Ocimi Gratissimi, citronella oil, patchouli oil, cassia oil again, essence is an amount of, hybrid pigment is an amount of; Add the residue liquid Paraffin, mixing filters; Get filtrating, packing promptly gets.
The skin acute toxicity of embodiment 1 is observed
2 groups of 8 branches of rabbit; Wherein the well word is drawn as the damaged skin group with blade by four skin depilatory districts, and other four is the intact skin group, only is applied to the depilation district with embodiment 1 quintessence oil 4.0ml/; Observe by the sky in 14 days; The behavioral activity of two groups of rabbit, diet, fur gloss and body weight have no effect, and no rabbit is dead, any acute toxic reaction do not occur.
The skin irritation of embodiment 1 is observed
2 groups of 6 branches of rabbit, wherein the well word is drawn as the damaged skin group with blade by 3 skin depilatory districts, and other 3 is the intact skin group; The QUMAO district is coated with embodiment 1 quintessence oil 1ml, and administration was removed remnants with warm water and tried thing after 24 hours; And in 1h, 24h, 48h; 72h hour, record was smeared the position and is had or not situation such as erythema, edema.The intact skin group was put in each observing time does not as a result all have erythema and the generation of edema phenomenon.The embodiment 1 quintessence oil smear zone of damaged skin has inadequate visible erythema at 1h, recovers in 24 hours; These article of explanation are to rabbit skin nonirritant, but can recover.
The skin hypersensitivity of embodiment 1 is observed
Albino guinea-pig back left side QUMAO is pressed the skin semar technique and is given embodiment 1 quintessence oil 0.2ml, continues 6 hours, and in administration after 24 hours; Excited administration, embodiment 1 quintessence oil 0.2ml is applied in QUMAO district, guinea pig back right side in the 28th day with the method repeat administration in the 14th day; Flush away is tried thing after 6 hours, observes at once, then in 24h; 48h, 72h observes once more, and skin does not have allergic phenomena generations such as erythema as a result.It is thus clear that embodiment 1 quintessence oil does not produce sensitization.
The anophelifuge test of embodiment 1
Four testers that attack is qualified wear the altex glove that arm exposes 40mm * 40mm, by 1.5 μ l/cm
2Dosage evenly smear embodiment 1, behind the 2h, hands is stretched into 2min in the qualified Aedes albopictus adult mosquito cage of attack, observe and to have or not mosquito to come to stop to fall to sucking blood.Every afterwards interval 1h test once.Do anophelifuge and lost efficacy as long as have a mosquito to come to suck blood promptly to declare.Write down its effective protecting time (h).The meansigma methods of effective protecting time of getting four bit test persons is tested traditional essential balm with method as the effective protecting time of embodiment 1.Acetonideexample 1 effective protecting time is 6 hours, and the effective protecting time of traditional essential balm is 3 hours.
The crowd of embodiment 1 is on probation
38 crowds that suffer from the red and swollen heat pain that mosquito bite causes use the quintessence oil of embodiment 1, and 38 patients are through treatment pruritus and all obviously improvement of local red and swollen phenomenon.In use do not produce uncomfortable sensation.
Claims (4)
1. quintessence oil with anti-inflammatory analgesic, refrigerant antipruritic and function of driving mosquitoes is characterized in that its formula components is made up of Mentholum, wintergreen oil, Oleum Camphora, Oleum Eucalypti, Oleum Ocimi Gratissimi, citronella oil, patchouli oil, cassia oil, liquid paraffin, flavoring agent and coloring agent etc.
2. quintessence oil formula components according to claim 1 is characterized in that its component percentages is Mentholum (20%～35%), wintergreen oil (13%～39%), Oleum Camphora (1%～5%), Oleum Eucalypti (1%～5%), Oleum Ocimi Gratissimi (1%～6%), citronella oil (3%～15%), patchouli oil (1%～5%), cassia oil (1%～5%), liquid paraffin is an amount of, flavoring agent is an amount of, coloring agent is an amount of.
3. quintessence oil formula components according to claim 1 is characterized in that coloring agent can be the pigment of natural extract or synthetic, promptly can use separately, also can use multiple pigment to mix composite use.The color of essential oil product is preferably faint yellow to yellow, yellow green, and light green is to green, more preferably light green.
4. quintessence oil according to claim 1 is characterized in that its dosage form is liniment, spray, varnish.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011104592550A CN102512609A (en) | 2011-12-27 | 2011-12-27 | Essential oil with anti-inflammatory, analgesic, cooling, itching-relieving and mosquito-dispelling functions |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2011104592550A CN102512609A (en) | 2011-12-27 | 2011-12-27 | Essential oil with anti-inflammatory, analgesic, cooling, itching-relieving and mosquito-dispelling functions |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102793753A (en) * | 2012-08-29 | 2012-11-28 | 刘晓平 | Health care conditioning oil |
| CN103004902A (en) * | 2012-11-21 | 2013-04-03 | 徐曼丽 | Traditional Chinese medicine scented sachet for dispelling mosquitoes and other insects |
| CN103920057A (en) * | 2014-05-04 | 2014-07-16 | 曹宏伟 | Medicament for treating otitis interna and use method thereof |
| CN105902453A (en) * | 2016-06-26 | 2016-08-31 | 黄植毅 | Mosquito-repellent spray |
| CN106614827A (en) * | 2016-12-28 | 2017-05-10 | 深圳市鸿邦礼品有限公司 | Mosquito-repelling combination and preparation method thereof and application |
| CN106726871A (en) * | 2016-11-18 | 2017-05-31 | 重庆市日用化学工业研究所 | Sweet wormwood mosquito-expelling and antipruritic floral water and preparation method thereof |
| CN108113929A (en) * | 2018-03-01 | 2018-06-05 | 遵义医学院 | A kind of mosquito-expelling and antipruritic compound essential oil of pure plant |
| CN108117929A (en) * | 2017-12-21 | 2018-06-05 | 漳州水仙药业股份有限公司 | A kind of essential oil and preparation method thereof |
| CN108850005A (en) * | 2018-05-27 | 2018-11-23 | 贵州省雷山县萌牛文创发展有限公司 | A kind of anophelifuge and preparation method thereof with Miao ethnic group's characteristic |
| CN113854285A (en) * | 2021-10-25 | 2021-12-31 | 成都彩虹电器（集团）股份有限公司 | Mosquito-repelling volatile core and preparation method thereof |
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| CN1631170A (en) * | 2004-11-05 | 2005-06-29 | 上海应用技术学院 | Anophelifuge essence combination with fruity odor and preparation method thereof |
| CN1745640A (en) * | 2005-10-18 | 2006-03-15 | 江苏隆力奇生物科技股份有限公司 | Preparation containing natural anophelifuge essence |
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- 2011-12-27 CN CN2011104592550A patent/CN102512609A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1631170A (en) * | 2004-11-05 | 2005-06-29 | 上海应用技术学院 | Anophelifuge essence combination with fruity odor and preparation method thereof |
| CN1745640A (en) * | 2005-10-18 | 2006-03-15 | 江苏隆力奇生物科技股份有限公司 | Preparation containing natural anophelifuge essence |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102793753A (en) * | 2012-08-29 | 2012-11-28 | 刘晓平 | Health care conditioning oil |
| CN102793753B (en) * | 2012-08-29 | 2014-09-17 | 刘晓平 | Health care conditioning oil |
| CN103004902A (en) * | 2012-11-21 | 2013-04-03 | 徐曼丽 | Traditional Chinese medicine scented sachet for dispelling mosquitoes and other insects |
| CN103920057A (en) * | 2014-05-04 | 2014-07-16 | 曹宏伟 | Medicament for treating otitis interna and use method thereof |
| CN105902453A (en) * | 2016-06-26 | 2016-08-31 | 黄植毅 | Mosquito-repellent spray |
| CN106726871A (en) * | 2016-11-18 | 2017-05-31 | 重庆市日用化学工业研究所 | Sweet wormwood mosquito-expelling and antipruritic floral water and preparation method thereof |
| CN106614827A (en) * | 2016-12-28 | 2017-05-10 | 深圳市鸿邦礼品有限公司 | Mosquito-repelling combination and preparation method thereof and application |
| CN108117929A (en) * | 2017-12-21 | 2018-06-05 | 漳州水仙药业股份有限公司 | A kind of essential oil and preparation method thereof |
| CN108113929A (en) * | 2018-03-01 | 2018-06-05 | 遵义医学院 | A kind of mosquito-expelling and antipruritic compound essential oil of pure plant |
| CN108850005A (en) * | 2018-05-27 | 2018-11-23 | 贵州省雷山县萌牛文创发展有限公司 | A kind of anophelifuge and preparation method thereof with Miao ethnic group's characteristic |
| CN113854285A (en) * | 2021-10-25 | 2021-12-31 | 成都彩虹电器（集团）股份有限公司 | Mosquito-repelling volatile core and preparation method thereof |
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Application publication date: 20120627 |