CN101940221B - Novel sterilizing effervescent tablets and preparation process thereof - Google Patents
Novel sterilizing effervescent tablets and preparation process thereof Download PDFInfo
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- CN101940221B CN101940221B CN201010266093.4A CN201010266093A CN101940221B CN 101940221 B CN101940221 B CN 101940221B CN 201010266093 A CN201010266093 A CN 201010266093A CN 101940221 B CN101940221 B CN 101940221B
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Abstract
The invention relates to an effervescent tablet component treated by water and microorganisms on the object surface and a preparation method thereof, in particular to novel sterilizing effervescent tablets and a preparation process thereof. The novel sterilizing effervescent tablet consists of the following substances in parts by mass: 0.1 to 0.3 part of trivalent silver ion compound, 30 to 60 parts of sodium bicarbonate, 36 to 56 parts of tartaric acid, and 40 to 55 parts of alcohol solution containing 5 percent polyvinylpyrrolidone. The preparation process comprises the following steps: uniformly grinding and mixing 0.1 to 0.3 part of the trivalent silver ion compound, 30 to 60 parts of the sodium bicarbonate and 36 to 56 parts of the tartaric acid after weighting, and adding 40 to 55 parts of the alcohol solution containing 5 percent polyvinylpyrrolidone as an adhesive; drying for 2 to 4 hours at 80 DEG C; and weighing 0.5 to 2g of the mixture to prepare into a tablet at the pressure of between 5 and 15 pounds. The effervescent tables have the effects and characteristics: sterilization which has strong killing capability to fungus, bacteria and the like by selecting the trivalent silver ion compound; and 2, quick and uniform release of effective components of the effervescent tablets in water with different temperatures (20-80).
Description
Technical field:
The effervescent tablet composition and the preparation method that the present invention relates to a kind of water and body surface microbiological treatment, be specially a kind of Novel sterilizing effervescent tablets and preparation technology thereof.
Background technology:
In life, inevitably contact the microorganisms such as noxious bacteria, fungi and virus, they are the main causes of bringing out mankind's communicate illness.In history, the famous event that infectious disease causes mankind's quantity to decline has, and causes Europe 1/3rd human mortalities' plague mid-term 14th century of Christian era, and 20 beginnings of the century caused the influenza of the whole world more than 2,000 ten thousand people's death.Modern age, the development of science and technology health level did not only make infectious disease wither away, and on the contrary, along with mankind's activity exchanges frequently, the density of population increases, and has caused the disease that traditional microorganism causes to increase.
In life, inevitably contact the microorganisms such as noxious bacteria, fungi and virus, they are the main causes of bringing out mankind's communicate illness.In history, the famous event that infectious disease causes mankind's quantity to decline has, and causes Europe 1/3rd human mortalities' plague mid-term 14th century of Christian era, and 20 beginnings of the century caused the influenza of the whole world more than 2,000 ten thousand people's death.Modern age, the development of science and technology health level did not only make infectious disease wither away, and on the contrary, along with mankind's activity exchanges frequently, the density of population increases, and has caused the disease that traditional microorganism causes to increase.
Harmful microorganism is present among human lives's various water bodies and body surface, and in swimming pool, bathing pool, various tablewares, toilet article, surface of denture, be also present in skin surface, thereby cause very large health problem.
Swimming pool is mainly the sterilization of application chlorine-containing disinfectant at present, but the organic chloride that chlorine-containing disinfectant produces when sterilization, as monochloro methane, carrene, chloroform, tetrachloromethane etc., can work the mischief to health.And another alternative is to add a little Chi at swimming pool discrepancy product, before entering swimming pool or after swimming, therefrom dived with sterilization, but plant disinfection way, process trouble and be difficult to management, wherein add not smelling good of active ingredient smell simultaneously, thereby by people institute need not mostly.
Common plunge bath or public place bathtub are not used by people because microorganism is difficult to process, and cause the large wasting of resources, have changed people's bathing mode.And people still show special preference to for bath in a tub, but at present technology be difficult to make people relieved utilize in public places bathing, be difficult in hotel, hotel used bath in a tub.
The sterilization of various tablewares, toilet article and artificial tooth artificial tooth is also a major issue.Table-ware disinfection at present adopts ultraviolet radiation modality mostly, this can reach certain bactericidal action, but this mode need to be used comparison expensive device, simultaneously as everybody knows a little less than ultraviolet penetration capacity, the effect that the sterilization ，Er lower floor that surface tableware can obtain is difficult to reach.
Now China enters aging society, and old man's number accounts for size of population proportion constantly to be increased, and artificial tooth is installed and is on the increase, and take oral disinfecting problem that artificial tooth, mouthwash be representative, becomes a large field of oral health.The take Chinese herbal medicine, organic compound that on market, occur are at present main thimerosal, but formality is incomplete, and effect is bad.
Therefore at present just need to be a kind of safe and reliable, good stability, bactericide easy to use, can be applied to the daily life fields such as water, tableware, oral hygiene, fabric.Silver is known before 2000 as bactericide, and researcher measures the relative efficiency of different metal antibacterial efficacy according to experiment, arranges as follows:
Ag＞Hg＞Cu＞Cd＞Ni＞Co＞Zn＞Fe＞Ca
Silver participates in bactericidal activity effect also the different valence state form of expression, and their sterilization relative ability is by as follows to weak arrangement by force: Ag (III) > Ag (II) > Ag (I) > Ag
Ag
4o
4+ 4NaOH+Na
2s
2o
8=2Ag
2o
3+ 2Na
2sO
4+ 2H
2o or
Ag
4O
4+4KOH+K
2S
2O
8＝2Ag
2O
3+2K
2SO
4+2H
2O
Summary of the invention:
Object of the present invention is exactly for solving sterilization effervescent tablet technical deficiency part at present, facilitating use advantage to unite the high effect broad-spectrum sterilization performance of trivalent silver iron compound and effervescent tablet, thereby a kind of Novel sterilizing effervescent tablets and preparation technology thereof are provided.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Novel sterilizing effervescent tablets, is specifically comprised of following material and quality proportioning:
Trivalent silver iron compound 0.1-0.3 part;
Sodium bicarbonate 30-60 part;
Tartaric acid 36-56 part;
Alcoholic solution 40-55 part containing 5% polyvinylpyrrolidone.
Described trivalent silver iron compound can be silver sesquioxide.
The present invention also provides the preparation technology of above-mentioned Novel sterilizing effervescent tablets simultaneously, its concrete preparation technology is as follows: respectively take trivalent silver iron compound 0.1-0.3 part, sodium bicarbonate 30-60 part, tartaric acid 36-56 part, be ground, separately add the alcoholic solution 40-55 part that contains 5% polyvinylpyrrolidone as adhesive, at 80 ℃, dry 2-4 hour, finally take 0.5-2g with 5-15 pound pressure film-making moulding.
Effervescent tablet of the present invention has following effect and feature:
1, bactericidal action: the trivalent silver iron compound of selecting, has the very strong ability of killing to fungi, bacterium etc.
2, effervescent tablet of the present invention (20-80) in different temperatures water all can discharge effective ingredient quickly and evenly.
Embodiment:
For better explanation the present invention, below in conjunction with case study on implementation and experimental result, the present invention is elaborated.
Embodiment 1:
Sodium bicarbonate 30g
Tartaric acid 36g
Trivalent silver iron compound 0.1g
Containing the molten 40mL of 5%PVP alcohol
Sodium bicarbonate, tartaric acid and the trivalent silver iron compound of getting aforementioned proportion, be ground, and separately adds alcoholic solution 40mL containing 5%PVP (polyvinylpyrrolidone) as adhesive, dries 2 hours for 80 ℃.Get 1g with 5 pounds of pressure film-making moulding.
Experiment 1
The effervescent tablet of embodiment 1 is got to 1 and be put in 500ml that the room temperature places (bacteria containing amount 100 in running water that carries disease germs, 000cpu/mL, test organisms is respectively Escherichia coli), allow effervescent tablet Spontaneous release, after 1 minute, from wherein respectively getting at random 20 μ l, evenly coat three aseptic flat boards, cultivate 16-18 hour, colony counting, the non-processor bacterium liquid of take is contrast.Result shows that it all can kill trial microorganism 100%.
Embodiment 2:
Sodium bicarbonate 60g
Tartaric acid 56g
Trivalent silver iron compound 0.3g
Containing the molten 55mL of 5%PVP alcohol
Get sodium bicarbonate, tartaric acid and trivalent silver iron compound, be ground, separately add alcoholic solution containing 5%PVP (polyvinylpyrrolidone) as adhesive, dry 2-4 hour for 80 ℃.Get 1g with 5-15 pound pressure film-making moulding.
Experiment 2:
The effervescent tablet of embodiment 2 is got to 3 and be invested at random the 2m that room temperature is placed
3carry disease germs (bacteria containing amount 10,000cpu/mL, test organisms staphylococcus aureus) in running water, allow effervescent tablet Spontaneous release, after 5 minutes, from wherein respectively getting at random 20 μ l, evenly coat three aseptic flat boards, cultivate 16-18 hour, colony counting, the non-processor bacterium liquid of take is contrast.Result shows that it all can kill trial microorganism 100%.
Test 3:
The effervescent tablet of embodiment 2 is got to 1 to be invested in the basin that a cotton towel and 5L running water are housed that room temperature places at random, and put into test organisms staphylococcus aureus, make final bacteria concentration reach 10,000cpu/mL, allows effervescent tablet Spontaneous release, after 15 minutes, from wherein respectively getting at random 20 μ l, evenly coat three aseptic flat boards, cultivate 16-18 hour, colony counting, take do not add effervescent tablet for contrasting.Result shows that it all can kill trial microorganism 100%.Such treatment samples and the control sample that do not add effervescent tablet are placed and to be spent the night simultaneously, towel peculiar smell not in treatment samples, and the control sample taste that gives out a foul smell.
Above-mentioned trivalent silver iron compound can be prepared by the following method: sodium hydroxide (potassium) 0.1-0.3 part, Tetrasilver tetroxide 1-2 part, sodium peroxydisulfate (potassium) 1-3 part, fully grind and be mixed evenly, grain fineness is 100-200 order, every 10 parts of upper mixtures add 3～5 parts of deionized waters (w/v), furnishing semi-fluid condition, after 50～80 ℃ of insulation 1～2h, filter, and with distilled water flushing at least three times, to wash away unreacted sodium peroxydisulfate (potassium) and sodium hydroxide (potassium) and product sodium sulphate (potassium) impurity, obtain nanometer trivalent silver iron compound.Described trivalent silver iron compound can be silver sesquioxide.
Claims (2)
1. a Novel sterilizing effervescent tablets, is characterized in that: described Novel sterilizing effervescent tablets is comprised of following material and quality proportioning:
The preparation technology of described Novel sterilizing effervescent tablets, respectively take trivalent silver iron compound 0.1-0.3 part, sodium bicarbonate 30-60 part, tartaric acid 36-56 part, be ground, separately add the alcoholic solution 40-55 part that contains 5% polyvinylpyrrolidone as adhesive, at 80 ℃, dry 2-4 hour, finally take 0.5-2g with 5-15 pound pressure film-making moulding.
2. Novel sterilizing effervescent tablets according to claim 1, is characterized in that: described trivalent silver iron compound is silver sesquioxide.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201010266093.4A CN101940221B (en) | 2010-08-30 | 2010-08-30 | Novel sterilizing effervescent tablets and preparation process thereof |
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| CN201010266093.4A CN101940221B (en) | 2010-08-30 | 2010-08-30 | Novel sterilizing effervescent tablets and preparation process thereof |
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| CN101940221A CN101940221A (en) | 2011-01-12 |
| CN101940221B true CN101940221B (en) | 2014-02-26 |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103845303B (en) * | 2014-02-24 | 2017-10-03 | 西安亮剑科技有限公司 | It is a kind of for high valency silver ion effervescent tablet of gynecological disease and preparation method thereof |
| CN105906005A (en) * | 2016-07-05 | 2016-08-31 | 山东建筑大学 | Compound effervescent tablets for water purification and disinfection and preparation method thereof |
| CN105883989A (en) * | 2016-07-05 | 2016-08-24 | 山东建筑大学 | Novel water purification and disinfection effervescent tablet and preparation method thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1234176A (en) * | 1999-01-15 | 1999-11-10 | 中国科学院生态环境研究中心 | Effervescence farm-chemical composition and production method thereof |
| CN1389436A (en) * | 2002-07-24 | 2003-01-08 | 唐山惠达陶瓷(集团)股份有限公司 | Sanitary ware with nano self-cleaning enamel and its making process |
| CN1628523A (en) * | 2003-12-16 | 2005-06-22 | 武汉绿世纪生物工程有限责任公司 | Effect enhanced sterilization composition and effervescence agent thereof |
| CN1653908A (en) * | 2005-01-14 | 2005-08-17 | 西北大学 | Method for preparing superfine composite inorganic antimicrobial agent |
| CN1751577A (en) * | 2004-09-24 | 2006-03-29 | 深圳市清华源兴生物医药科技有限公司 | Composite sterilizing agent contg. silver and zinc, prepn. method and application thereof |
-
2010
- 2010-08-30 CN CN201010266093.4A patent/CN101940221B/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1234176A (en) * | 1999-01-15 | 1999-11-10 | 中国科学院生态环境研究中心 | Effervescence farm-chemical composition and production method thereof |
| CN1389436A (en) * | 2002-07-24 | 2003-01-08 | 唐山惠达陶瓷(集团)股份有限公司 | Sanitary ware with nano self-cleaning enamel and its making process |
| CN1628523A (en) * | 2003-12-16 | 2005-06-22 | 武汉绿世纪生物工程有限责任公司 | Effect enhanced sterilization composition and effervescence agent thereof |
| CN1751577A (en) * | 2004-09-24 | 2006-03-29 | 深圳市清华源兴生物医药科技有限公司 | Composite sterilizing agent contg. silver and zinc, prepn. method and application thereof |
| CN1653908A (en) * | 2005-01-14 | 2005-08-17 | 西北大学 | Method for preparing superfine composite inorganic antimicrobial agent |
Non-Patent Citations (2)
| Title |
|---|
| 游泳池用二价与三价银消毒剂;黄汉生;《日用化学品科学》;19960430(第02期);第7页第3段 * |
| 黄汉生.游泳池用二价与三价银消毒剂.《日用化学品科学》.1996,(第02期), |
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Owner name: SUZHOU TNY SANJIA NANOMETER TECHNOLOGY CO., LTD. Free format text: FORMER OWNER: JIANGSU BANG'AN NEW MATERIALS TECHNOLOGY CO., LTD. Effective date: 20130515 |
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Effective date of registration: 20130515 Address after: 06. 215006, Room 501, northwest of Suzhou nanometer City, 99 Jinji Road, Suzhou Industrial Park, Jiangsu, Suzhou, China Applicant after: SUZHOU TAILI SANJIA NANO TECHNOLOGY CO., LTD. Address before: Double road Suzhou Industrial Park Suzhou city Jiangsu province 215122 No. 2 Applicant before: Jiangsu Bang'an New Materials Technology Co., Ltd. |
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