CN101912044A - Composition for promoting muscle generation and preparation method thereof - Google Patents
Composition for promoting muscle generation and preparation method thereof Download PDFInfo
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- CN101912044A CN101912044A CN2010102525097A CN201010252509A CN101912044A CN 101912044 A CN101912044 A CN 101912044A CN 2010102525097 A CN2010102525097 A CN 2010102525097A CN 201010252509 A CN201010252509 A CN 201010252509A CN 101912044 A CN101912044 A CN 101912044A
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- trimethylglycine
- dihydropyridine
- glycocyamine
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Abstract
The invention relates to a composition for promoting muscle generation, which comprises the following components in parts by weight: 7-8 parts of guanidinoacetic acid, 7-8 parts of trimethylglycine, 4-6 parts of dihydropyridine and 78-82 parts of starch. The preparation method of the composition comprises the following steps of: (1) premixing raw materials with vectors; and (2) preparing the composition. The trimethylglycine is used as a methyl donor aiming at the effect of the guanidinoacetic acid on the synthesis of creatine organisms so as to promote the livestock and poultry muscle generation and the growth, and in addition, the dihydropyridine is added and used as a catalyst of a creatine generation reaction to ensure that the effects on promoting the livestock and poultry muscle generation and the growth are further strengthened. The invention has scientific formula and simple preparation process and is suitable for production practices.
Description
Technical field
The present invention relates to the composition and method of making the same that a kind of short muscle generates.
Background technology
Because " clenbuterol hydrochloride " can promote the muscle of pig to generate really, improves ketoboidies dressing percentage and lean meat percentage, therefore, although classified as the forbidding product by country, but still remains incessant after repeated prohibition.Trace it to its cause still main owing to there are not better substitute products.If invent a kind of alternative " clenbuterol hydrochloride ", and non-harmful product is arranged, " clenbuterol hydrochloride " nature will be released feed addictive market so.
Glycocyamine is a kind of material that self exists in animal and the human body, plays the part of important role in the biosynthesis of creatine.Glycocyamine is the synthetic intermediate material of creatine.Synthetic by the arginic base of narrowing in vivo with glycine, further accept Methyl transporters and generate creatine.Phosphocreatine is formed by creatine and ATP, and creatine is then formed Methyl transporters by methionine to glycocyamine, and glycocyamine is then produced by the transfer of the amidino groups between arginine and the glycine.The glycine, arginine, methionine and the glycocyamine that participate in this process are effective for improving muscle function.The research of Degussa company report shows, glycocyamine is as the effect of feed addictive: add the glycocyamine of 0.92kg/ ton in the chicken feed, after feeding 42 days, compare with control group, body weight increases by 7%, and feedstuff-meat ratio descends 6%.The body weight part that increases mainly is to increase muscle rather than fat or water.Even the addition of glycocyamine has only the 0.32kg/ ton, body weight increases by 3% after 42 days, and feedstuff-meat ratio descends 3%, and iff adding methyl amimoacetic acid 0.4kg/ ton, then the identical experiment phase is not observed any weight, feedstuff-meat ratio is different with control group.
Trimethylglycine (betaine) is a kind of biogenic forage additive, has been widely used in fields such as additive, livestock and poultry cultivation, aquaculture.Trimethylglycine main effect in animal body provides methyl, and methyl is the indispensable important substance of various metabolisms in the animal body, participates in multiple biochemical processes such as fat metabolism, amino acid whose transfer directly.Thereby trimethylglycine has played the effect of saving choline and methionine, promotes the biosynthesis of muscle, and can relax stress, promote growth of animals or poultry.
Dihydropyridine be a kind of easy to use, addition is little, it is safe and effective to feed, the novel multifunctional additive that has no side effect., promotion mineral matter anti-oxidant except that having absorbs and improves the BA of animal body immunity, the more important thing is that dihydropyridine can improve the livestock and poultry hormone serum level, have growth promotion, improve weightening finish and improve the animal products quality, promote the effect that muscle generates.
Promote growth of animals or poultry, improve the muscle production rate is the theme of the eternal pursuit of aquaculture always.Glycocyamine, trimethylglycine and dihydropyridine all have the BA that promotes growth of animals or poultry.In addition, glycocyamine is played the part of important role in the biosynthesis of creatine, and trimethylglycine can be as the methyl donor of the synthetic creatine of glycocyamine, and common reaction generates creatine; Dihydropyridine can further promote the biosynthesis of creatine by improving the livestock and poultry hormone serum level.
Summary of the invention
For addressing the above problem, the present invention provides a kind of and can promote that muscle generates in the livestock and poultry body according to the effect of glycocyamine in the creatine biosynthesis, has the composition and method of making the same of tangible growth promotion and the effect of reduction feedstuff-meat ratio.
The composition that short muscle of the present invention generates is made up of the component of following parts by weight: glycocyamine 7-8 part, trimethylglycine 7-8 part, dihydropyridine 4-6 part, starch 78-82 part.
The preparation of compositions method that short muscle of the present invention generates comprises the steps:
1), the premix of raw material and carrier: add 1/3 starch carrier in the mixer of cleaning, add wherein a kind of of glycocyamine, trimethylglycine or dihydropyridine then, stir 5min, add two kinds of remaining raw materials more successively, each stirs 5min.
2), preparation composition: will remain 2/3 starch carrier and join in the raw material and carrier behind premix, and stir 15min, and make to mix, and be packed as the 500g/ bag then, and be and urge muscle generation composition.
The beneficial effect of the composition and method of making the same that the short muscle of the present invention generates is: short muscle involved in the present invention generates composition at the effect of glycocyamine in the creatine biosynthesis, with the trimethylglycine is methyl donor, generates and growth promotion to promote livestock and poultry muscle.Add dihydropyridine simultaneously,, livestock and poultry muscle generation and growth promoting function are further strengthened its catalyst as the creatine reaction of formation.Scientific composition, preparation technology is simple, is suitable for production practices.
By experimental study and optimization improvement for many years, and animal interpolation evidence, said preparation not only can substitute " clenbuterol hydrochloride ", and short muscle nucleus formation effect is remarkable, and has tangible growth promotion and the effect of reduction feedstuff-meat ratio.
The specific embodiment
The composition and method of making the same that the short muscle of the present invention is generated is described further below.
Embodiment 1
The composition that short muscle of the present invention generates, the component by following parts by weight per ton is formed: glycocyamine 75kg, trimethylglycine 75kg, dihydropyridine 50.0kg, starch 800.0kg.
The preparation of compositions method that short muscle of the present invention generates comprises the steps:
1), the premix of raw material and carrier: add the starch carrier of 240kg in the mixer of cleaning, add the 75kg glycocyamine then, stir 5min, add 75kg trimethylglycine and 50.0kg dihydropyridine more successively, each stirs 5min.
2), preparation composition: will remain the 560kg starch carrier and join in the raw material and carrier behind the step 1) premix, and stir 15min, and make to mix, and be packed as the 500g/ bag then, and be short muscle generation composition, and seal, room temperature storage.
Embodiment 2
The composition that short muscle of the present invention generates, the component by following parts by weight per ton is formed: glycocyamine 70kg, trimethylglycine 70kg, dihydropyridine 40.0kg, starch 820.0kg.
The preparation of compositions method that short muscle of the present invention generates comprises the steps:
1), the premix of raw material and carrier: add the starch carrier of 260kg in the mixer of cleaning, add the 70kg trimethylglycine then, stir 5min, add 70kg glycocyamine and 40.0kg dihydropyridine more successively, each stirs 5min.
2), preparation composition: will remain the 560kg starch carrier and join in the raw material and carrier behind the step 1) premix, and stir 15min, and make to mix, and be packed as the 500g/ bag then, and be short muscle generation composition, and seal, room temperature storage.
Embodiment 3
The composition that short muscle of the present invention generates, the component by following parts by weight per ton is formed: glycocyamine 80kg, trimethylglycine 80kg, dihydropyridine 60.0kg, starch 780.0kg.
The preparation of compositions method that short muscle of the present invention generates comprises the steps:
1), the premix of raw material and carrier: add the starch carrier of 270kg in the mixer of cleaning, add the 60.0kg dihydropyridine then, stir 5min, add 80kg glycocyamine and 80kg trimethylglycine more successively, each stirs 5min.
2), preparation composition: will remain the 510kg starch carrier and join in the raw material and carrier behind the step 1) premix, and stir 15min, and make to mix, and be packed as the 500g/ bag then, and be short muscle generation composition, and seal, room temperature storage.
Short muscle involved in the present invention generates composition at the effect of glycocyamine in the creatine biosynthesis, is methyl donor with the trimethylglycine, generates and growth promotion to promote livestock and poultry muscle.Add dihydropyridine simultaneously,, livestock and poultry muscle generation and growth promoting function are further strengthened its catalyst as the creatine reaction of formation.Scientific composition, preparation technology is simple, is suitable for production practices.
The application process that short muscle involved in the present invention generates composition is:
Pig: this product 500g/T spice is fed;
Chicken: this product 1000g/T spice is fed.
Above embodiment is described preferred implementation of the present invention; be not that scope of the present invention is limited; design under the prerequisite of spirit not breaking away from the present invention; various distortion and improvement that the common engineers and technicians in this area make technical scheme of the present invention all should fall in the definite protection domain of claims of the present invention.
Claims (2)
1. the composition that short muscle generates is characterized in that, is made up of the component of following parts by weight: glycocyamine 7-8 part, trimethylglycine 7-8 part, dihydropyridine 4-6 part, starch 78-82 part.
2. the preparation of compositions method that short muscle generates is characterized in that, comprises the steps:
1), the premix of raw material and carrier: add 1/3 starch carrier in the mixer of cleaning, add wherein a kind of of glycocyamine, trimethylglycine or dihydropyridine then, stir 5min, add two kinds of remaining raw materials more successively, each stirs 5min.
2), preparation composition: will remain 2/3 starch carrier and join in the raw material and carrier of step 1) behind premix, and stir 15min, and make to mix, and be the composition of urging the muscle generation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010102525097A CN101912044A (en) | 2010-08-13 | 2010-08-13 | Composition for promoting muscle generation and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010102525097A CN101912044A (en) | 2010-08-13 | 2010-08-13 | Composition for promoting muscle generation and preparation method thereof |
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| CN101912044A true CN101912044A (en) | 2010-12-15 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2010102525097A Pending CN101912044A (en) | 2010-08-13 | 2010-08-13 | Composition for promoting muscle generation and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111990546A (en) * | 2020-08-17 | 2020-11-27 | 固安君德同创生物工程有限公司 | Composition of guanidinoacetic acid and synergist thereof, preparation method and application |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1964633A (en) * | 2004-06-09 | 2007-05-16 | 底古萨股份公司 | Guanidino acetic acid used as a food additive |
| CN101132786A (en) * | 2005-03-04 | 2008-02-27 | 澳泽化学特罗斯特贝格有限公司 | Salts, addition compounds and complex compounds of guanidinoacetic acid |
| CN101267746A (en) * | 2005-08-02 | 2008-09-17 | 澳泽化学特罗斯特贝格有限公司 | Liquid formulation based on a guanidinoacetic acid component |
-
2010
- 2010-08-13 CN CN2010102525097A patent/CN101912044A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1964633A (en) * | 2004-06-09 | 2007-05-16 | 底古萨股份公司 | Guanidino acetic acid used as a food additive |
| CN101132786A (en) * | 2005-03-04 | 2008-02-27 | 澳泽化学特罗斯特贝格有限公司 | Salts, addition compounds and complex compounds of guanidinoacetic acid |
| CN101267746A (en) * | 2005-08-02 | 2008-09-17 | 澳泽化学特罗斯特贝格有限公司 | Liquid formulation based on a guanidinoacetic acid component |
Non-Patent Citations (1)
| Title |
|---|
| 《国外畜牧学（猪与禽）》 20100125 王志军 摘 利用几种营养元素合理搭配彻底赶走"瘦肉精" 第108-109页 1-2 第30卷, 第1期 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111990546A (en) * | 2020-08-17 | 2020-11-27 | 固安君德同创生物工程有限公司 | Composition of guanidinoacetic acid and synergist thereof, preparation method and application |
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| DD01 | Delivery of document by public notice |
Addressee: Zhao Jinping Document name: Notification of Passing Preliminary Examination of the Application for Invention |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| DD01 | Delivery of document by public notice |
Addressee: Qingdao Tiantong Bio-Tech Co., Ltd. Document name: Notification of Publication and of Entering the Substantive Examination Stage of the Application for Invention |
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| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20101215 |