CN101837169B - Ultrasound thermal therapy system for superficial tissues - Google Patents
Ultrasound thermal therapy system for superficial tissues Download PDFInfo
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- CN101837169B CN101837169B CN2010101223121A CN201010122312A CN101837169B CN 101837169 B CN101837169 B CN 101837169B CN 2010101223121 A CN2010101223121 A CN 2010101223121A CN 201010122312 A CN201010122312 A CN 201010122312A CN 101837169 B CN101837169 B CN 101837169B
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Abstract
The invention discloses an ultrasound thermal therapy system for superficial tissues, belonging to the technical field of biomedical engineering. The ultrasound thermal therapy system comprises a computer, a microcontroller, a digital frequency synthesis unit, a filtering and preamplification unit, a power amplifier, a power feedback monitoring loop and a combined focusing ultrasound therapy head, wherein the computer is connected with the microcontroller which is connected with the digital frequency synthesis unit; the digital frequency synthesis unit is connected with the filtering and preamplification unit which is connected with the power amplifier; the power amplifier is connected with the combined focusing ultrasound therapy head; one end of the power feedback monitoring loop is connected with the microcontroller; and the other end of the power feedback monitoring loop is connected with the power amplifier. The invention overcomes the defect that the traditional ultrasound thermal therapy system controls the therapy effect only by the experience of doctors; the invention can effectively monitor and accurately adjust the numerical value of high-frequency electric power so as to improve the therapy quality of the superficial tissues in the ultrasound thermal therapy process.
Description
Technical field
What the present invention relates to is the system in a kind of biomedical engineering technology field, specifically is a kind of ultrasound thermal therapy system for superficial tissues.
Background technology
It is another conventional therapy means after surgical operation, radiotherapy and chemotherapy that the thermal therapy system that utilizes Biological Effects of Physical Factors such as ultrasonic, radio frequency or microwave to develop is used for the treatment of tissue.Ultrasound thermal therapy is easy to reach the even heating of tissue tissue, and curative effect is good, has no side effect, and does not have ionization or electromagnetic radiation, neither can bring Health cost also can not cause the pollution of environment to the medical worker, is a kind of means of emerging effective treated tissue.Show that at animal experiment and clinical research in the superficial tissue treatment, ultrasound thermal therapy is one of effective means equally, it not only has direct killing effect to histiocyte, and can strengthen the sensitivity of histiocyte to chemotherapy and radiation.
Through existing literature search is found, Chinese patent application number is: 01144259.X, name is called: supersonic gynopathic and dermatosis therapeutic instrument, this technology realizes the electrical power Self Adaptive Control by control unit, but this technology exists significantly not enough: first, the high-frequency electric power that drives the combined focus ultrasonic therapeutic head lacks effectively monitoring, be that having or not of its electrical power can only be differentiated by system, and can't clearly survey the numerical values recited of its high-frequency electric power, and then may work as electrical power numerical value and cause when out of control the damage of superficial tissue or fall flat, that is to say that safety remains further to be improved; The second, the signal of telecommunication produces part and adopts analogue technique to realize mostly, and the error on indexs such as pulsewidth, frequency and amplitude is big and adjust constantly like this, is unfavorable for system dynamics accurately control in real time, that is to say that the control effectiveness remains further to be improved.
Summary of the invention
The objective of the invention is to overcome the above-mentioned deficiency of prior art, a kind of ultrasound thermal therapy system for superficial tissues is provided, the present invention can monitor and the numerical values recited of adjustment system high-frequency electric power accurately effectively, and then has improved at superficial tissue ultrasound thermal therapy process safe and effectiveness.
The present invention is achieved by the following technical solutions:
The present invention includes: computer, microcontroller, the numerical frequency synthesis unit, filtering and pre-amplifier unit, power amplifier, Feedback of Power monitoring circuit and combined focus ultrasonic therapeutic head, wherein: the computer transmission parameter set information that links to each other with microcontroller, microcontroller links to each other with the numerical frequency synthesis unit and transmits control information, link to each other with filtering and the pre-amplifier unit pulsewidth amplitude modulation information of transmitting discreteization of numerical frequency synthesis unit, filtering and pre-amplifier unit link to each other with power amplifier and transmit the analog quantity information of pulsewidth amplitude modulation(PAM), the power amplifier transmission electric power value information that links to each other with the combined focus ultrasonic therapeutic head, one end of the Feedback of Power monitoring circuit transmission pulse width information that links to each other with microcontroller, the other end of the Feedback of Power monitoring circuit transmission electric power value information that links to each other with power amplifier.
Described Feedback of Power monitoring circuit is used for gathering the sampling high-frequency electric power, this loop comprises: sampling and attenuation units, detection processing unit and pulsewidth processing unit, wherein: sampling and the attenuation units transmission electric power value information that links to each other with power amplifier, the detection processing unit amplitude information after the transmission attenuation that links to each other with sampling and attenuation units, the pulsewidth processing unit links to each other with the detection processing unit and transmits pulse width information, and microcontroller links to each other with the pulsewidth processing unit and transmits the digital information of pulsewidth.
Described sampling and attenuation units are transformators.
Described numerical frequency synthesis unit is used to produce the driving signal of pulsewidth amplitude modulation(PAM), this unit comprises: the SPI interface module, frequency dividing circuit, phase accumulator, address selector, address latch, waveform output module and internal storage, wherein: the SPI interface module transmission frequency control word information that links to each other with phase accumulator, phase accumulator links to each other with address selector and transmits the address information of internal storage, address latch links to each other with address selector and transmits the address information of internal storage, address selector links to each other with internal storage and transmits the address information of internal storage, internal storage is connected with the waveform output module and transmits the pulse width signal digital information, and frequency dividing circuit links to each other with phase accumulator and transmits reference clock signal.
Compared with prior art, the invention has the beneficial effects as follows: overcome the deficiency that the conventional ultrasound thermal therapy system can only be controlled therapeutic effect with doctors experience, the present invention can monitor effectively and accurately adjust the numerical values recited of high-frequency electric power, and then has improved the therapeutic quality in superficial tissue ultrasound thermal therapy process.
Description of drawings
Fig. 1 is that system of the present invention forms sketch map;
Wherein: the 1-computer; The 2-microcontroller; 3-numerical frequency synthesis unit; 4-filtering and pre-amplifier unit; The 5-power amplifier; 6-Feedback of Power monitoring circuit; 7-sampling and attenuation units; 8-detection processing unit; 9-pulsewidth processing unit; 10-combined focus ultrasonic therapeutic head.
Fig. 2 is the formation sketch map of numerical frequency synthesis unit of the present invention;
Wherein: the 11-SPI interface module; The 12-frequency dividing circuit; The 13-phase accumulator; The 14-address selector; The 15-address latch; 16-waveform output module; The 17-internal storage.
The specific embodiment
Below in conjunction with accompanying drawing system of the present invention is further described: present embodiment is being to implement under the prerequisite with the technical solution of the present invention, provided detailed embodiment and concrete operating process, but protection scope of the present invention is not limited to following embodiment.
Embodiment
As shown in Figure 1, present embodiment comprises: comprising: computer 1, microcontroller 2, numerical frequency synthesis unit 3, filtering and pre-amplifier unit 4, power amplifier 5, Feedback of Power monitoring circuit 6 and combined focus ultrasonic therapeutic head 10, wherein: computer 1 is by the universal high speed EBI transmission parameter set information that links to each other with microcontroller 2, microcontroller 2 links to each other with numerical frequency synthesis unit 3 and transmits control information, link to each other with filtering and the pre-amplifier unit 4 pulsewidth amplitude modulation information of transmitting discreteization of numerical frequency synthesis unit 3, filtering and pre-amplifier unit 4 link to each other with power amplifier 5 and transmit the analog quantity information of pulsewidth amplitude modulation(PAM), the power amplifier 5 transmission electric power value information that links to each other with combined focus ultrasonic therapeutic head 10, one end of the Feedback of Power monitoring circuit 6 transmission pulse width information that links to each other with microcontroller 2, the other end of the Feedback of Power monitoring circuit 6 transmission electric power value information that links to each other with power amplifier 5.
The model of described microcontroller 2 is: ATMega16.
The model of described filtering and pre-amplifier unit 4 is: AD8002.
The model of described power amplifier 5 is: RCP-100W.
Described Feedback of Power monitoring circuit 6 is used for gathering the sampling high-frequency electric power, this loop comprises: sampling and attenuation units 7, detection processing unit 8 and pulsewidth processing unit 9, wherein: sampling and the attenuation units 7 transmission electric power value information that links to each other with power amplifier 5, detection processing unit 8 amplitude information after the transmission attenuation that links to each other with sampling and attenuation units 7, pulsewidth processing unit 9 links to each other with detection processing unit 8 and transmits pulse width information, and microcontroller 2 links to each other with pulsewidth processing unit 9 and transmits the digital information of pulsewidth.
Described sampling and attenuation units 7 are transformators.
The model of described detection processing unit 8 is: AD8002.
The model of described pulsewidth processing unit 9 is: Intel8253.
As shown in Figure 2, described numerical frequency synthesis unit 3 is used to produce the driving signal of pulsewidth amplitude modulation(PAM), this unit comprises: SPI interface module 11, frequency dividing circuit 12, phase accumulator 13, address selector 14, address latch 15, waveform output module 16 and internal storage 17, wherein: the SPI interface module 11 transmission frequency control word information that links to each other with phase accumulator 13, phase accumulator 13 links to each other with address selector 14 and transmits the address information of internal storage, address latch 15 links to each other with address selector 14 and transmits the address information of internal storage, address selector 14 links to each other with internal storage 17 and transmits the address information of internal storage 17, internal storage 17 is connected with waveform output module 16 and transmits the pulse width signal digital information, and frequency dividing circuit 12 links to each other with phase accumulator 13 and transmits reference clock signal.
The model of numerical frequency synthesis unit 3 is in the present embodiment: Flex10K10, its inner each module realizes by the Hardware Description Language VHDL programming, microcontroller 2 deposits adjusted Wave data in the internal storage 17 in through address latch 15 and address selector 14 by the bus multiplex mode, microcontroller 2 sends frequency control word to phase accumulator 13 by SPI interface module 11 then, and last phase accumulator 13 reads the data of internal storage 17 and then sends waveform output module 16 to through address latch 15 and address selector 14 according to frequency control word.In addition, frequency dividing circuit 12 is used for producing the reference clock (50MHz) that makes phase accumulator 13 operate as normal and control its precision and waveform quality.
The work process of present embodiment is:
1) computer 1 is sent to microcontroller 2 through the universal high speed EBI with setup parameters such as power, frequency, pulsewidths, and microcontroller 2 is exported corresponding instruction control figure frequency synthesis unit 3 to produce the discrete signal that comprises pulsewidth, frequency and amplitude accurately according to the parameter of setting; This discrete signal produces the high-frequency high-power signal of telecommunication through filtering and pre-amplifier unit 4 rear drive power amplifiers 5 again;
2) the high-frequency high-power signal of telecommunication encourages combined focus ultrasonic therapeutic head 10 on the one hand, feeds back to sampling and attenuation units 7 on the other hand, delivers to detection processing unit 8 after sampling and attenuation units 7 are transformed to small-signal with it; Detection processing unit 8 output useful signals are changed through pulsewidth processing unit 9 again, export the digital signal that microcontroller 2 can be accepted and handle then to;
3) microcontroller 2 internal conditions digital signal that receives and the parameter of originally setting carried out parameter adjustment and corrections such as electrical power, on the one hand send adjustment information universal high speed EBI to computer 1 so that monitoring in real time, on the other hand according to revise adjust back new argument output command adapted thereto control figure frequency synthesis unit 3 until electrical power signal in controlled setting indication range; If the feedback digital signal that microcontroller 2 receives and original parameter basically identical of setting then need not adjusted.
Present embodiment novel structure and scheme are reasonable, have adopted Feedback of Power monitoring circuit 6 to carry out the Self Adaptive Control of electrical power, have improved the safety and the reliability of treatment; In addition current advanced digital frequency synthesis technology is incorporated in the development of control device, improved the precision of technical parameters such as power, frequency, pulsewidth, thereby strengthened the effectiveness of treatment.
Claims (3)
1. ultrasound thermal therapy system for superficial tissues, comprise: computer, microcontroller, filtering and pre-amplifier unit, power amplifier and combined focus ultrasonic therapeutic head, it is characterized in that, also comprise: the numerical frequency synthesis unit, wherein: the computer transmission parameter set information that links to each other with microcontroller, microcontroller links to each other with the numerical frequency synthesis unit and transmits control information, link to each other with filtering and the pre-amplifier unit pulsewidth amplitude modulation information of transmitting discreteization of numerical frequency synthesis unit, filtering and pre-amplifier unit link to each other with power amplifier and transmit the analog quantity information of pulsewidth amplitude modulation(PAM), the power amplifier transmission electric power value information that links to each other with the combined focus ultrasonic therapeutic head, one end of the Feedback of Power monitoring circuit transmission pulse width information that links to each other with microcontroller, the other end of the Feedback of Power monitoring circuit transmission electric power value information that links to each other with power amplifier;
Described numerical frequency synthesis unit produces the driving signal of pulsewidth amplitude modulation(PAM), this unit comprises: the SPI interface module, frequency dividing circuit, phase accumulator, address selector, address latch, waveform output module and internal storage, wherein: the SPI interface module transmission frequency control word information that links to each other with phase accumulator, phase accumulator links to each other with address selector and transmits the address information of internal storage, address latch links to each other with address selector and transmits the address information of internal storage, address selector links to each other with internal storage and transmits the address information of internal storage, internal storage is connected with the waveform output module and transmits the pulse width signal digital information, and frequency dividing circuit links to each other with phase accumulator and transmits reference clock signal.
2. ultrasound thermal therapy system for superficial tissues according to claim 1, it is characterized in that, described Feedback of Power monitoring circuit is used for gathering the sampling high-frequency electric power, this loop comprises: sampling and attenuation units, detection processing unit and pulsewidth processing unit, wherein: sampling and the attenuation units transmission electric power value information that links to each other with power amplifier, the detection processing unit amplitude information after the transmission attenuation that links to each other with sampling and attenuation units, the pulsewidth processing unit links to each other with the detection processing unit and transmits pulse width information, and microcontroller links to each other with the pulsewidth processing unit and transmits the digital information of pulsewidth.
3. ultrasound thermal therapy system for superficial tissues according to claim 2 is characterized in that described sampling and attenuation units are transformators.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010101223121A CN101837169B (en) | 2010-03-12 | 2010-03-12 | Ultrasound thermal therapy system for superficial tissues |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2010101223121A CN101837169B (en) | 2010-03-12 | 2010-03-12 | Ultrasound thermal therapy system for superficial tissues |
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| CN101837169A CN101837169A (en) | 2010-09-22 |
| CN101837169B true CN101837169B (en) | 2011-11-16 |
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| CN2010101223121A Expired - Fee Related CN101837169B (en) | 2010-03-12 | 2010-03-12 | Ultrasound thermal therapy system for superficial tissues |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103027708A (en) * | 2011-10-09 | 2013-04-10 | 北京汇福康医疗技术有限公司 | Monitoring method and monitoring system for operating state of ultrasonic transducer |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2315567Y (en) * | 1998-03-13 | 1999-04-21 | 清华大学 | New supersonic Doppler blood flow detector |
| CN1775328A (en) * | 2005-12-01 | 2006-05-24 | 上海交通大学 | Wide focal domain phased array focusing ultrasonic transducer exciting bunk |
| CN1832350A (en) * | 2006-04-14 | 2006-09-13 | 西安电子科技大学 | Multiple carrier-frequency digital frequency source |
| CN1919146A (en) * | 2006-07-31 | 2007-02-28 | 深圳市德力凯电子有限公司 | Wide band via-skull Doppler system and method for frequency conversion cerebrovascular blood flow rate detection |
-
2010
- 2010-03-12 CN CN2010101223121A patent/CN101837169B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2315567Y (en) * | 1998-03-13 | 1999-04-21 | 清华大学 | New supersonic Doppler blood flow detector |
| CN1775328A (en) * | 2005-12-01 | 2006-05-24 | 上海交通大学 | Wide focal domain phased array focusing ultrasonic transducer exciting bunk |
| CN1832350A (en) * | 2006-04-14 | 2006-09-13 | 西安电子科技大学 | Multiple carrier-frequency digital frequency source |
| CN1919146A (en) * | 2006-07-31 | 2007-02-28 | 深圳市德力凯电子有限公司 | Wide band via-skull Doppler system and method for frequency conversion cerebrovascular blood flow rate detection |
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