CN101732517B - Chinese medicinal composition for treating canine distemper and preparation method thereof - Google Patents

Abstract

The invention provides a Chinese medicinal composition for treating canine distemper and a preparation method thereof, and relates to a medicament for treating the canine distemper. The Chinese medicinal composition is prepared by mixing isatis indigotica fort, great burdock achene, Chinese pulsatilla root, astragalus, gambir plant, honeysuckle flower, platycodon root, weeping forsythiae capsule,liquoric root, baical skullcap root, indigowoad leaf, kudzuvine root, rhizoma arisaematis cum bile, halloysit and golden thread; mixing raw materials; adding water to soak and decoct the mixture for certain time; and filtering the mixture. The composition has the advantages of wide materials, low cost, safety, effectiveness, no medicament resistance and convenient use, and has the effects of clearing heat and detoxicating, clearing liver and improving vision, moistening lung and transforming phlegm, cooling blood and checking dysentery, extinguishing wind and resolving tetany, upbearing the clear and downbearing the turbid, and strengthening organic immunologic functions.

Description

A kind of Chinese medicine composition of treating canine distemper and preparation method thereof

Technical field

The invention belongs to Chinese medicine composition, particularly be a kind of treatment dog, Vulpes and Nyctereutes procyonoides canine distemper composition and method of making the same.

Background technology

Canine distemper is a kind of acute, the deadly infectious disease of Canis animals (dog, fox, recoon dog, jackal, the wolf) susceptible that caused by canine distemper virus (CDV).Primary disease can pass through alimentary infection, also can in case the canine distemper case is arranged, often involve full crowd and other raiser very soon through respiratory infectious.Primary disease all can take place throughout the year, and sickness rate and fatality rate are high, is the healthy first infectious disease of harm dog class.In addition, along with the fast development that the Vulpes Nyctereutes procyonoides is cultured, this disease extensively is present in the intensive places of Vulpes Nyctereutes procyonoides raising such as China's North, Northeast China, is called as one of Vulpes Nyctereutes procyonoides three big eqpidemic diseases.In recent years, the trend that this disease all has rising in the sickness rate and the fatality rate of China, in non-immune beast sickness rate and fatality rate higher, and the immuning failure phenomenon happens occasionally.Primary disease does not still have the specific treatment medicine at present, mainly adopts measures such as Western medicine supporting treatment and anti-inflammation clinically, and effect is undesirable.Anti-CDV serum and monoclonal antibody also can only have certain curative effect to the animal of their early stage, in case clinical symptoms appears, the prognosis extreme difference, and the treatment cost is expensive.Have bibliographical information to adopt the method treatment canine distemper of the combination of Chinese and Western medicine, also obtained certain curative effect, high curative rate is 54.2%, but the course of treatment is many more than first quarter moon, and all is that cost is expensive, is difficult to promote to pet dog.The canine distemper special preparation of Zu Kejian is applicable to the treatment of respiratory symptom type canine distemper disease dog, and its range of application is restricted.The Chinese medicine preparation that is used to treat Vulpes Nyctereutes procyonoides canine distemper still belongs to blank at present; Treatment cost and unsatisfactory curative effect that Western medicine is expensive make a lot of Canis animals raisers have to abandon the treatment to this disease; This disease brings serious economy loss for the Canis animals aquaculture, and the Chinese medicine composition of development treatment canine distemper develops in a healthy way significant for dog and Vulpes Nyctereutes procyonoides aquaculture.

Summary of the invention

The object of the invention is exactly the problem that exists to above-mentioned treatment canine distemper, researchs and develops a kind of composition and method of making the same of treating dog and Vulpes Nyctereutes procyonoides canine distemper, reach to improve the canine distemper cure rate, and purpose with low cost, that have no side effect.

The objective of the invention is to realize like this: said composition is prepared by following raw material and consumption: Radix Isatidis 10-20g, Fructus Arctii 10g-20g, Radix Pulsatillae 10g-20g, Radix Astragali 10g-20g, Ramulus Uncariae Cum Uncis 10g-20g, Flos Lonicerae 10g-20g, Radix Platycodonis 5-10g, Fructus Forsythiae 5-10g, Radix Glycyrrhizae 5-10g, Radix Scutellariae 5-10g, Folium Isatidis 5-10g, Radix Puerariae 5-10g, Arisaema Cum Bile 5-10g, Halloysitum Rubrum 3-6g, Rhizoma Coptidis 3-6g.In dosage, add normal-temperature water 2000-2500ml in whole Radix Isatidis, Fructus Arctii, the Radix Pulsatillae, the Radix Astragali, Ramulus Uncariae Cum Uncis, Flos Lonicerae, Radix Platycodonis, Fructus Forsythiae, Radix Glycyrrhizae, Radix Scutellariae, Folium Isatidis, Radix Puerariae, Arisaema Cum Bile, Halloysitum Rubrum, the Rhizoma Coptidis; Soaked 30 minutes; 30-45 at a simmer minute, filter and remove residue got the about 40mL of medicinal liquid; Add 1500-2000mL water in the medicinal residues after filtering again, 30-45 at a simmer minute, cross and filter the about 40mL of medicinal liquid, merge twice medicinal liquid, obtain the Chinese medicine composition of potion treatment canine distemper.

Extensive, with low cost, safe and effective, no Drug resistance, easy to use that this compositions is drawn materials has the effect of heat-clearing and toxic substances removing, liver heat removing and eyesight improving, moistening the lung and resolving phlegm, eliminating pathogenic heat from blood to cure dysentery, the spasmolytic that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., ascending the clear and descending the turbid, enhancing human body immunity function.

The dog, Vulpes, the Nyctereutes procyonoides that suffer from canine distemper are adopted the said composition treatment that makes an experiment, cure over thousands of head, cure rate reaches more than 70%, and is evident in efficacy, so said composition is significant for the sound development of treatment canine distemper, promotion dog and fur-bearing animal aquaculture.

The specific embodiment

Give an actual example below and describe the present invention.

Get Radix Isatidis 20g, Fructus Arctii 15g, Radix Pulsatillae 18g, Radix Astragali 14g, Ramulus Uncariae Cum Uncis 15g, Flos Lonicerae 16g, Radix Platycodonis 6g, Fructus Forsythiae 7g, Radix Glycyrrhizae 8g, Radix Scutellariae 9g, Folium Isatidis 5g, Radix Puerariae 10g, Arisaema Cum Bile 9g, Halloysitum Rubrum 4g, Rhizoma Coptidis 5g respectively.

Process for preparation is following: the above-mentioned solid content that takes by weighing is added the 2300ml normal-temperature water, soaked 40 minutes at a simmer 30 minutes; Filter and remove residue gets the about 40mL of medicinal liquid; Add the 1800mL normal-temperature water in the medicinal residues after filtering again, 40 minutes at a simmer, cross and filter the about 40mL of medicinal liquid; Merge the medicinal liquid of twice filtration gained, obtain the Chinese medicine composition that potion is treated canine distemper.

Method for using is following: the compositions of the above-mentioned treatment canine distemper that is mixed with is reduced to 20-30 ℃ irritate clothes for trouble dog, sick Vulpes, sick Nyctereutes procyonoides; Sooner or later respectively once; 1 dose of every day, 3～7 doses of logotypes take the circumstances into consideration to add and subtract each component dosage according to the state of an illness and the big I of body weight in the prescription claimed range.

Treatment case 1

In May, 2006, the sick ermine that the author suffers from canine distemper for 3 foster Nyctereutes procyonoides families in 3 different villages, Heilongjiang Province county has carried out diagnosis and treatment, and this 3 family is cultured 275,173 and 165 respectively, and ill Nyctereutes procyonoides is all at the 4-6 monthly age; All do not inject canine distemper vaccine, most sick Nyctereutes procyonoides courses of disease are 7-10 days, mainly show refusing to eat, fever; Shed tears, the eye conjunctiva rubescent, purulence nose liquid is arranged, dyspnea appears in the sick Nyctereutes procyonoides that has, most sick Nyctereutes procyonoidess have loose bowels; Instability of gait appears in the development along with the state of an illness, and last whole body is twitched dead.The morbidity of part Nyctereutes procyonoides is more anxious, does not show manifest symptom and just twitches dead suddenly.Local veterinary treats by eperythrozoonosis, and adds that antibiotic and transfusion carry out auxiliary treatment, and the state of an illness is not controlled.When go to a doctor in here, the Nyctereutes procyonoides of 3 the Nyctereutes procyonoides fields nearly first quarter moon of falling ill successively, accumulative total death is respectively 45,25 and 22, and still has new case to occur, and is diagnosed as canine distemper through lab testing.Then advise that the raiser has taked emergency control measure.Sick Nyctereutes procyonoides is used above-mentioned traditional Chinese medicine composition for treating, serve on 7 doses 1 dose of every day, and symptom promptly alleviated after poultry master master stated medication, and 97 examples are treated at three families altogether, cure 69 examples, dead 32 examples, cure rate 71%.

Treatment case 2

In year JIUYUE in March, 2005 to 2009, the author successively accepts canine distemper positive case 62 examples altogether for medical treatment, and wherein 44 examples are respiratory symptom type canine distemper; 8 examples are digestion symptom type hundstaupe, and 6 examples are nervous symptoms type canine distemper, mixed type canine distemper 8 examples; Kind has its dog of the scholar of Kazakhstan, Alaska dog and Sa Moye dog, Canis lupus familiaris, Jing Ba and hybrid dog etc.; Relate to 26 kinds altogether, public dog sickness rate accounts for 57%, and the bitch sickness rate accounts for 43%.Through above-mentioned traditional Chinese medicine composition for treating, be clearly better behind most sick dog 3d, recover normal behind the 7d, after one week of drug withdrawal, detect negative with canine distemper antigen quick detection test paper bar.Cure rate is 48 examples, dead 14 examples, and cure rate is 77%.

Treatment case 3

On May 9th, 2008, a raiser buys a collection of arctic fox in the breed sub-district, Heilongjiang Province from the other places, the cage house of just putting into the sub-district without quarantining.May 14, original young Vulpes began morbidity, and involved full crowd rapidly, all death of a Vulpes surplus in the of 100 of its livestock on hand in the 11d.Because the householder do not notify epidemic situation at once, epidemic situation further enlarges, and a Vulpes surplus May whole sub-district on the 26th column memory 10,000 falls ill 890; Sick Vulpes mainly shows hyperpyrexia, subtracts food, vomiting, and asoscope is dry; Eye conjunctiva flushing, swelling, in addition purulent conjunctivitis appears, around eyes is come off by hair, palpebra inferior is bonded together by purulent secretion on the weight person, the nose sexual secretion of suppurating; Dyspnea, cough, diarrhoea is mixed with blood sometimes.The sick Vulpes of epilepsy symptom appears in the spasm that has, tic, more than dead in the 1-2d.Through the urgent consultation of doctors and lab testing, be diagnosed as canine distemper.The suggestion raiser takes emergency control measure, and sick Vulpes is treated with above-mentioned Chinese medicine composition, by June 7, treats 973 morbidity foxes altogether, cures 678, and cure rate is 72%.

Claims (2)

1. Chinese medicine composition of treating canine distemper is characterized in that said composition is by following raw material and consumption preparation: Radix Isatidis 10-20g, Fructus Arctii 10g-20g, Radix Pulsatillae 10g-20g, Radix Astragali 10g-20g, Ramulus Uncariae Cum Uncis 10g-20g, Flos Lonicerae 10g-20g, Radix Platycodonis 5-10g, Fructus Forsythiae 5-10g, Radix Glycyrrhizae 5-10g, Radix Scutellariae 5-10g, Folium Isatidis 5-10g, Radix Puerariae 5-10g, Arisaema Cum Bile 5-10g, Halloysitum Rubrum 3-6g, Rhizoma Coptidis 3-6g.

2. the Chinese medicine composition method for preparing of a treatment canine distemper as claimed in claim 1; It is characterized in that adding in Radix Isatidiss whole in dosage, Fructus Arctii, the Radix Pulsatillae, the Radix Astragali, Ramulus Uncariae Cum Uncis, Flos Lonicerae, Radix Platycodonis, Fructus Forsythiae, Radix Glycyrrhizae, Radix Scutellariae, Folium Isatidis, Radix Puerariae, Arisaema Cum Bile, Halloysitum Rubrum, the Rhizoma Coptidis normal-temperature water 2000-2500ml; Soaked 30 minutes; 30-45 at a simmer minute, filter and remove residue got the about 40mL of medicinal liquid; Add 1500-2000mL water in the medicinal residues after filtering again, 30-45 at a simmer minute, cross and filter the about 40mL of medicinal liquid, merge twice medicinal liquid, obtain the Chinese medicine composition of potion treatment canine distemper.