CN101700029B - Bactericidal composition containing SYP-7017 and carbendazim - Google Patents
Bactericidal composition containing SYP-7017 and carbendazim Download PDFInfo
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- CN101700029B CN101700029B CN 200910185658 CN200910185658A CN101700029B CN 101700029 B CN101700029 B CN 101700029B CN 200910185658 CN200910185658 CN 200910185658 CN 200910185658 A CN200910185658 A CN 200910185658A CN 101700029 B CN101700029 B CN 101700029B
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- carbendazim
- bactericidal composition
- bacterium ester
- chlorine nalidixic
- nalidixic bacterium
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Abstract
The invention discloses a bactericidal composition containing SYP-7017 and carbendazim, which consists of SYP-7017 and carbendazim, has high bactericidal activity and can retard the generation and the development of drug resistance of pathogens, reduce the overall dosage on unit area and further realize the purposes of economy, high efficiency and environmental protection. The bactericidal composition has high effects of preventing and treating the plant fungal diseases, and the two medicaments have significant synergy; the bactericidal composition can replace part of high-price pesticides for use, reduce the dosage, effectively reduce the ecological damage and the environmental pollution and improve the yield and the quality of crops; the SYP-7017 and the carbendazim in the bactericidal composition have low toxicity and are safe to people and animals, beneficial organisms and environmental safety; and the bactericidal composition can retard the drug resistance of the bacteria to the single medicament.
Description
Technical field
The present invention relates to the disinfectant use in agriculture field, specifically a kind of bactericidal composition that contains chlorine nalidixic bacterium ester and carbendazim.
Background technology
Disclose in Chinese invention patent application (CN1814590A) and the PCT patent application (WO2006081759A1) class new have a Fungicidal active compound, wherein the 1 No. 3 compound is shown in structural formula I:
The Universal Chinese character of formula I compound is called chlorine nalidixic bacterium ester, chemical name: N-methoxyl group-N-[2-[[(3,5,6-trichloropyridine-2-yl) oxygen] methyl] phenyl] methyl carbamate is a kind of high-effective broad-spectrum fungicide.The pathogens such as wheat, powdery mildew of cucumber, rice blast, rice green smut, rice sheath blight disease, bakanae disease of rice, wheat sharp eyespot, wheat scab, root rotof flax, corn northern leaf blight and southern leaf blight, sclerotinia rot of colza, graw mold of tomato, apple canker, melon anthracnose, cucumber fusarium axysporum, cotton verticillium wilt, cotton wilt had very high bacteriostatic activity.Main Function mechanism is that impact is melanic synthetic.
Carbendazim has following structural formula:
Chemical name: N-benzimidazolyl-2 radicals-aminocarbamic acid methyl esters, be China's crop fungal disease control agent commonly used, main mechanism is the formation of Spindle in the interference cell mitosis, and most of fungus-caused plant diseases such as botrytis, sickle-like bacteria, Septoria musiva, sclerotinite, Verticillium dahliae, rhizoctonia are had certain control efficiency.
Chlorine nalidixic bacterium ester is methoxy acrylic ester compounds, and carbendazim is carbamate compound, and the two mechanism of action is single, can cause fungi to produce resistance such as long-term single use, causes preventive effect to descend.
Summary of the invention
The invention provides a kind of bactericidal composition that contains chlorine nalidixic bacterium ester and carbendazim, have the bactericidal activity height, delay that the pathogen pesticide resistance produces and development, and dosage total on the unit are is descended, thereby realize purpose economic, efficient, environmental protection.
Technical scheme of the present invention is:
A kind of bactericidal composition that contains chlorine nalidixic bacterium ester and carbendazim is characterized in that: described bactericidal composition is comprised of chlorine nalidixic bacterium ester and carbendazim; The mass ratio of described chlorine nalidixic bacterium ester and carbendazim is 1: 0.5-50.
The described bactericidal composition that contains chlorine nalidixic bacterium ester and carbendazim is characterized in that: described bactericidal composition is prepared into aqueous suspension agent, oil suspending agent, thermal fog, suspension emulsion, wetting powder, granule, water-dispersible granules, effervescent tablet, granula or micro-capsule suspension as the primary raw material component.
The described bactericidal composition that contains chlorine nalidixic bacterium ester and carbendazim is characterized in that: described bactericidal composition is applied in the control crop fungal disease.
The described bactericidal composition that contains chlorine nalidixic bacterium ester and carbendazim is characterized in that: the mass ratio of described chlorine nalidixic bacterium ester and carbendazim is 1: (1-36).
The described bactericidal composition that contains chlorine nalidixic bacterium ester and carbendazim is characterized in that: the mass ratio of described chlorine nalidixic bacterium ester and carbendazim is 1: (4-21).
The described bactericidal composition that contains chlorine nalidixic bacterium ester and carbendazim is characterized in that: the mass ratio of described chlorine nalidixic bacterium ester and carbendazim is 1: (6-13.5).
The present invention has two classes in the bactericide of different mechanism of action, be the methoxy acrylic bactericide chlorine nalidixic bacterium ester and have that to inhale conductive Bavistin in good combined, and be processed into and produce easy-to-use preparation, reduced the risk of disease fungus to single bactericide generation resistance, also reduce cost, prolonged simultaneously the service life of each component in the bactericidal composition.
Chlorine nalidixic bacterium ester of the present invention belongs to methoxy acrylic bactericide, novel structure, mode of action uniqueness; Carbendazim is the carbamate bactericide, mainly disturbs mitosis; The two combination, has in actual use the bactericidal activity height, and two class medicaments possess different structure types and discrepant mechanism of action, the two combination can delay the generation of pathogen pesticide resistance and development to a greater extent, and dosage total on the unit are is descended, thereby realize goal of the invention economic, efficient, environmental protection.
Remarkable result of the present invention and advantage are:
The present invention has higher control efficiency to the crop fungal disease, has the notable synergistic effect between two components; Can replace part high price pesticide species, and reduce dosage, effectively reduce ecological disruption and environmental pollution, and can improve crop yield and quality; Chlorine nalidixic bacterium ester and carbendazim all belong to the toxicity such as low among the present invention, and to people and animals, beneficial organism, Environmental security; Can delay germ to the pesticide resistance of single medicament.
Embodiment
At first measure the EC of chlorine nalidixic bacterium ester and carbendazim two single compounds (hereinafter to be referred as medicament)
50(medicine is to the biopotency safety indexes of target) is according to the EC of two single medicaments
50Set the portfolio ratio of two medicaments by the Horsfall method, and according to Horsfall coefficient of synergism C value, determine suitable composition ratio, then press the abundant method proved of Sun Yun.
The test objective thing is powdery mildew of strawberry, but does not limit so.Test adopts the moisturizing of leaf dish to protect green method.Each processes 4 repetitions, each is processed with the quantitative spraying liquid 2mL of Potter tower, taking out nature after sedimentation is processed dries, 24 hours inoculation powdery mildew of strawberry pathogen conidial powders behind the medicine, postvaccinal strawberry leaves dish moves to (22 ℃ of incubators, 10000LUX illumination 16h and 18 ℃ of dark 8h alternate treatment, relative moisture remain on 75-85%), connect bacterium after 10 days, the investigation preventive effect.The EC of each medicament is obtained in linear regression analysis between probit value by preventive effect and the logarithm value of serial drug concentration
50, and calculate Horsfall coefficient of synergism C and the abundant CTC value of Sun Yun.C value and CTC value calculating method are as follows:
Suppose a, b is that two medicament A, B are at EC
50Actual measurement bacteriostasis rate during dosage, if A and the B shared ratio in composition is respectively pA, pB, then:
Expection bacteriostasis rate (p)=apA+bpB
Coefficient of synergism (C)=actual bacteriostasis rate (P)/expection bacteriostasis rate (p)
Horsfall thinks: synergy when C＞1, and antagonism when C＜1, and Horsfall thinks that the C value is larger, the synergy of built agent is larger.
CTC=100 (1/ composition EC
50)/∑ (single chemical content/corresponding medicament EC
50)
Sun Yunpei thinks: CTC＞120 belong to synergistic effect; CTC＜80 belong to antagonism; Between be summation action.
Table one chlorine nalidixic bacterium ester and carbendazim composition are to the Horsfall measurement result of powdery mildew of strawberry
Can analyze from above data, the chlorine nalidixic bacterium ester of different proportion and carbendazim composition are different to the control efficiency of powdery mildew of strawberry, and on the whole, its ratio has synergistic effect in 1: 1 to 1: 36 scope, and wherein maximum enhancing proportions is 1: 9,
Table two chlorine nalidixic bacterium ester and carbendazim composition are to the CTC measurement result of powdery mildew of strawberry
For further proved, measured 1: 9 chlorine nalidixic bacterium ester and carbendazim composition to the virulence of powdery mildew of strawberry with the abundant method of Sun Yun, the results are shown in table two, as can be seen from Table II, its synergy is very remarkable, and the CTC value reaches 176.9, and is consistent with above assay method acquired results.
The superiority of this composition that the field control effect of table three and the following example further specifies:
The land for growing field crops drug effect * of table three, several diseases of 35% chlorine nalidixic bacterium ester carbendazim suspending agent (1: 9) control
* the field control effect of other diseases is seen the following example.
The invention will be further described below in conjunction with embodiment, but be not limited to this.
Embodiment 1
With chlorine nalidixic bacterium ester 5g, carbendazim 45g, sodium lignin sulfonate 8g, diffusant sodium methylene bis-naphthalene sulfonate 4g, White Carbon black adds to 100g, mixes, and mixture carries out air-flow crushing, makes wetting powder.Every mu of 80-100g of this wetting powder is used for the control powdery mildew of strawberry, and control efficiency can reach 97.53%, is higher than triazole bactericidal agent triazolone, propiconazole, Difenoconazole and the kresoxim-methyl of conventional amount used.
Embodiment 2
With chlorine nalidixic bacterium ester 3.5g, carbendazim 31.5g, sodium lignin sulfonate 5g, fatty alcohol polyoxy ethyl ether 2g, phenethyl phenol formaldehyde resin APEO 3g, antifreeze urea 6g, antisettling agent xanthans 0.1g, suitable quantity of water is to 100g, mix, through the wet method sand milling, homogenizing makes aqueous suspension agent.Every mu of 1 00g of this aqueous suspension agent is used for the control powdery mildew of strawberry, and control efficiency can reach 94.67%, is higher than triazole bactericidal agent triazolone, propiconazole, Difenoconazole and the kresoxim-methyl of conventional amount used, and can overcome the drug injury problem of triazole bactericidal agent.Every mu of 100-120g is used for control rice green smut effect 81%, and is suitable with propiconazole, and the control efficiency of rice sheath blight disease, rice blast is reached more than 93.33%, is better than jinggangmeisu and the tricyclazole of conventional amount used.The effect of preventing and treating bakanae disease of rice by grain weight 0.2-0.3% seed dressing or seed soaking can reach more than 90%.
Embodiment 3
With chlorine nalidixic bacterium ester 6g, carbendazim 54g, fatty alcohol polyoxy ethyl ether 5g, polyoxyethylene nonylphenol ether 3g, starch 1.2g, sodium bicarbonate 2g, bentonite 10g, kaolin adds to 100g, mixes, and granulation behind the air-flow crushing makes water-dispersible granules.Every mu of 75-80g of this water-dispersible granules is used for control wheat powdery mildew and head blight, and control efficiency can reach 87.67%, is better than the constant control efficiency of carbendazim and triazolone; Being used for preventing and treating the anthracnose of grape effect can reach more than 90%.The climing rot effect of control watermelon reaches more than 85%.
Embodiment 4
With chlorine nalidixic bacterium ester 4g, carbendazim 34g, polyoxyethylene sorbitol oleate 6g, lignosulfonates 2g, polyalkoxylated pure 6g, fatty alcohol-polyoxyethylene ether 5g, dimethyl silicone polymer 0.05g, rapeseed oil or salad oil be to 100g, mixes after broken by the sand mill wet-milling to get oil-suspending agent.This oil suspends, when making thermal fog and using, every mu of 100g to diesel oil or salad oil 50g (being used as smoke agent) with hot mist machine control of maize northern and southern leaf blight or powdery mildew of strawberry, anthracnose; Or to water with conventional medical instruments spraying control of maize northern and southern leaf blight, rust, control efficiency all reaches more than 91.8%.
Embodiment 5
With chlorine nalidixic bacterium ester 5g, carbendazim 20g, lauryl sodium sulfate 6g, pull open powder 9g, Sodium Benzoate 6g, bentonite 15g, mixing and air-flow crushing are to crossing 400 mesh sieves, pulverized citric acid 20g, the potash 20g of 80 mesh sieves with drying, mix, compacting namely gets 25% effervescent tablet in flakes in tablet press machine.This effervescent tablet is automatically disintegration in water, and forms uniform suspension, every mu with the 100-150g effervescent tablet with spray-on process prevent and treat sclerotinia rot of colza, pears anthracnose effect reaches more than 87%.
Claims (5)
1. bactericidal composition that contains chlorine nalidixic bacterium ester and carbendazim, it is characterized in that: described bactericidal composition is to contain chlorine nalidixic bacterium ester and carbendazim; The mass ratio of described chlorine nalidixic bacterium ester and carbendazim is 1: 1-36.
2. a kind of bactericidal composition that contains chlorine nalidixic bacterium ester and carbendazim according to claim 1, it is characterized in that: described bactericidal composition is prepared into aqueous suspension agent, oil suspending agent, wetting powder, water-dispersible granules, effervescent tablet by the primary raw material component.
3. the bactericidal composition that contains chlorine nalidixic bacterium ester and carbendazim according to claim 1, it is characterized in that: described bactericidal composition is applied to prevent and treat crop fungal disease.
4. the bactericidal composition that contains chlorine nalidixic bacterium ester and carbendazim according to claim 1, it is characterized in that: the mass ratio of described chlorine nalidixic bacterium ester and carbendazim is 1: 4-21.
5. the bactericidal composition that contains chlorine nalidixic bacterium ester and carbendazim according to claim 1, it is characterized in that: the mass ratio of described chlorine nalidixic bacterium ester and carbendazim is 1: 6-13.5.
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| CN 200910185658 CN101700029B (en) | 2009-11-27 | 2009-11-27 | Bactericidal composition containing SYP-7017 and carbendazim |
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| CN 200910185658 CN101700029B (en) | 2009-11-27 | 2009-11-27 | Bactericidal composition containing SYP-7017 and carbendazim |
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| CN101700029B true CN101700029B (en) | 2013-03-20 |
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| CN104054731B (en) * | 2014-06-21 | 2016-03-16 | 安徽省农业科学院植物保护与农产品质量安全研究所 | A kind of bactericidal composition and application thereof containing chlorine nalidixic bacterium ester and probenazole |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005104847A1 (en) * | 2004-04-30 | 2005-11-10 | Basf Aktiengesellschaft | Fungicidal mixtures |
| CN101258852A (en) * | 2008-04-10 | 2008-09-10 | 江苏宝灵化工股份有限公司 | Carbamate and prochloraz fungicidal composition |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005104847A1 (en) * | 2004-04-30 | 2005-11-10 | Basf Aktiengesellschaft | Fungicidal mixtures |
| CN101258852A (en) * | 2008-04-10 | 2008-09-10 | 江苏宝灵化工股份有限公司 | Carbamate and prochloraz fungicidal composition |
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Owner name: PLANT PROTECTION AND QUALITY + SAFETY OF AGRICULTU Free format text: FORMER NAME: INSTITUTE OF BOTANY PROTECTION;ANHUI ACADEMY OF AGRICULTURAL SCIENCES |
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Address after: Hefei City, Anhui Province Agricultural Road 230031 No. 40 Patentee after: Plant Protection and Quality & Safety of Agricultural Products Institute, Anhui Academy of Agricultural Sciences Address before: Hefei City, Anhui Province Agricultural Road 230031 No. 40 Patentee before: Plant Protection Institute, Anhui Academy of Agricultural Sciences |
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