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CN101487013A - Ptp1b基因突变的检测以及其在癌症诊断中的应用 - Google Patents

Ptp1b基因突变的检测以及其在癌症诊断中的应用 Download PDF

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Publication number
CN101487013A
CN101487013A CNA2009100461859A CN200910046185A CN101487013A CN 101487013 A CN101487013 A CN 101487013A CN A2009100461859 A CNA2009100461859 A CN A2009100461859A CN 200910046185 A CN200910046185 A CN 200910046185A CN 101487013 A CN101487013 A CN 101487013A
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CN
China
Prior art keywords
ptp1b
seq
gene
sequence
ptp1b gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2009100461859A
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English (en)
Chinese (zh)
Inventor
梅文瀚
郑新民
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shanghai Jiaotong University
Shanghai Jiaotong University School of Medicine
Original Assignee
Shanghai Jiaotong University School of Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Jiaotong University School of Medicine filed Critical Shanghai Jiaotong University School of Medicine
Priority to CNA2009100461859A priority Critical patent/CN101487013A/zh
Publication of CN101487013A publication Critical patent/CN101487013A/zh
Priority to PCT/CN2009/075005 priority patent/WO2010091581A1/fr
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CNA2009100461859A 2009-02-13 2009-02-13 Ptp1b基因突变的检测以及其在癌症诊断中的应用 Pending CN101487013A (zh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CNA2009100461859A CN101487013A (zh) 2009-02-13 2009-02-13 Ptp1b基因突变的检测以及其在癌症诊断中的应用
PCT/CN2009/075005 WO2010091581A1 (fr) 2009-02-13 2009-11-18 Détection de mutations du gène ptp1b et leurs utilisations dans le diagnostic des cancers

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CNA2009100461859A CN101487013A (zh) 2009-02-13 2009-02-13 Ptp1b基因突变的检测以及其在癌症诊断中的应用

Publications (1)

Publication Number Publication Date
CN101487013A true CN101487013A (zh) 2009-07-22

Family

ID=40890074

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2009100461859A Pending CN101487013A (zh) 2009-02-13 2009-02-13 Ptp1b基因突变的检测以及其在癌症诊断中的应用

Country Status (2)

Country Link
CN (1) CN101487013A (fr)
WO (1) WO2010091581A1 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010091581A1 (fr) * 2009-02-13 2010-08-19 上海交通大学医学院 Détection de mutations du gène ptp1b et leurs utilisations dans le diagnostic des cancers
WO2011079668A1 (fr) * 2009-12-29 2011-07-07 上海新号源生物科技有限公司 Groupe de gènes ptpα mutants dans la tumeur maligne et son procédé de production
CN107699620A (zh) * 2017-11-20 2018-02-16 薛守海 甲基化基因组合物及制备诊断预示Luminal B型乳腺癌骨转移试剂盒的用途
CN107904309A (zh) * 2017-11-20 2018-04-13 薛守海 甲基化基因组合物及制备诊断预示三阴性型乳腺癌骨转移试剂盒的用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1275722A1 (fr) * 2001-07-11 2003-01-15 Novo Nordisk A/S La variante P387L de la Protéine Tyrosine Phophatase 1B est associée avec le diabète de type 2 et démontre une phosphorylation réduite de la sérine de PTP-1B in vitro
CA2357559A1 (fr) * 2001-09-19 2003-03-19 Donald A. Fujita Diagnostic et pronostic d'une tumeur faisant appel a la proteine tyrosine phosphatase 1b (ptp 1b)
CN101487013A (zh) * 2009-02-13 2009-07-22 上海交通大学医学院 Ptp1b基因突变的检测以及其在癌症诊断中的应用

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010091581A1 (fr) * 2009-02-13 2010-08-19 上海交通大学医学院 Détection de mutations du gène ptp1b et leurs utilisations dans le diagnostic des cancers
WO2011079668A1 (fr) * 2009-12-29 2011-07-07 上海新号源生物科技有限公司 Groupe de gènes ptpα mutants dans la tumeur maligne et son procédé de production
CN107699620A (zh) * 2017-11-20 2018-02-16 薛守海 甲基化基因组合物及制备诊断预示Luminal B型乳腺癌骨转移试剂盒的用途
CN107904309A (zh) * 2017-11-20 2018-04-13 薛守海 甲基化基因组合物及制备诊断预示三阴性型乳腺癌骨转移试剂盒的用途

Also Published As

Publication number Publication date
WO2010091581A1 (fr) 2010-08-19

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Open date: 20090722