CN109777639B - Preparation for disinfecting and cleaning hard surface of air conditioner and general objects and preparation method thereof - Google Patents
Preparation for disinfecting and cleaning hard surface of air conditioner and general objects and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a preparation for disinfecting and sanitation cleaning of hard surfaces of air conditioners and general objects and a preparation method thereof, wherein the preparation comprises, by mass, 0.2-5 parts of quaternary ammonium salt cationic compounds, 0.01-2 parts of guanidine compounds, 0.1-1 part of chelating agents, 5-18 parts of fatty alcohols, 2-10 parts of active agents and the balance of water. According to the invention, through the combination of cationic active substances guanidine and quaternary ammonium salt active factors, the complementary advantages of the cationic active substances guanidine and quaternary ammonium salt active factors are formed, and the cross composite design of fatty alcohol, an active agent and a chelating agent is adopted, so that a multiple active factor system is formed, the sterilization speed is high, the sterilization spectrum is wide, and the use is convenient; the metal corrosion inhibition capability is strong, so that the product and the technology can be better applied to the surface disinfection and sanitary cleaning of air conditioners, food processing equipment and general objects in public places such as families, hospitals, hotels and the like.
Description
Technical Field
The invention belongs to the technical field of sanitary disinfection and cleaning agents, and particularly relates to a preparation for disinfecting and sanitary cleaning of hard surfaces of air conditioners and general objects and a preparation method thereof.
Background
Air conditioners in families, public environments, production workshops, research rooms, farms and the like are increasingly popular, are frequently used, are densely-populated communication areas, are also silted breeding areas of germs, viruses and dust, and are very easy to cause cross infection among human beings and other animals and overflow of epidemic diseases. The bactericidal active ingredients of the current air-conditioning and general object surface disinfectants are generally pure DP300, PCMX, quaternary ammonium salt, alcohols or guanidine active ingredients, the prepared preparation has narrow bactericidal spectrum, obvious drug resistance and insufficient bactericidal activity along with the variation development of germs and viruses, and the preparation needs longer sterilization time in practical application, so that the product cannot be used conveniently and quickly.
In order to change the current laggard product development technology and application design level, a new generation of air conditioner and a general object surface disinfectant are developed to make up for the defects of the existing products, achieve the optimal effect of the products, and enable the products to be more convenient and fast to use, which is a technical problem to be solved in the field.
Disclosure of Invention
This section is for the purpose of summarizing some aspects of embodiments of the invention and to briefly introduce some preferred embodiments. In this section, as well as in the abstract and the title of the invention of this application, simplifications or omissions may be made to avoid obscuring the purpose of the section, the abstract and the title, and such simplifications or omissions are not intended to limit the scope of the invention.
The present invention has been made in view of the above-mentioned technical drawbacks.
Accordingly, in one aspect of the present invention, the present invention overcomes the deficiencies of the prior art by providing a formulation for disinfection and sanitization of hard surfaces for air conditioning and general objects.
In order to solve the technical problems, the invention provides the following technical scheme: a preparation for disinfection and sanitation of hard surfaces of air conditioners and general objects comprises quaternary ammonium salt cationic compound, guanidine compound, chelating agent, fatty alcohol, active agent and water;
wherein, the composition comprises, by mass, 0.2-5 parts of quaternary ammonium salt cationic compound, 0.01-2 parts of guanidine compound, 0.1-1 part of chelating agent, 5-18 parts of fatty alcohol, 2-10 parts of active agent, and the balance of water;
the quaternary ammonium salt cationic compound includes: one or more of dimethyl bisdodecyl ammonium chloride, dodecyl dimethyl ethylbenzene oxyethyl ammonium bromide, dimethyl bisdecyl ammonium chloride, dimethyl bisdecyl ammonium bromide, dimethyl bisdecyl ammonium carbonate, diethyl bisdodecyl ammonium carbonate, dimethyl bistetradecyl ammonium chloride, dimethyl bishexadecyl ammonium chloride, benzethonium chloride and benzethonium bromide.
As a preferred embodiment of the preparation according to the invention for disinfecting and hygienically cleaning hard surfaces of air conditioners and objects in general: the guanidine compounds include: one or more of polyhexamethylene biguanide or a derivative of the polyhexamethylene monoguanidine.
As a preferred embodiment of the preparation according to the invention for disinfecting and hygienically cleaning hard surfaces of air conditioners and objects in general: the active agents include: one or more of alkyl glycoside, propyl betaine, dodecyl betaine, fatty alcohol polyoxyethylene ether, oxidized cocamidopropyl amine, polyvinyl alcohol 400 and polyvinyl alcohol 600.
As a preferred embodiment of the preparation according to the invention for disinfecting and hygienically cleaning hard surfaces of air conditioners and objects in general: the fatty alcohols include: one or more of ethanol, ethylene glycol, propanol, isopropanol, propylene glycol, glycerol, butanol, and 1, 3-butanediol.
As a preferred embodiment of the preparation according to the invention for disinfecting and hygienically cleaning hard surfaces of air conditioners and objects in general: the chelating agent comprises: one or more of ethylene diamine tetraacetic acid, ethylene diamine tetraacetic acid disodium, ethylene diamine tetraacetic acid tetrasodium, ethylene diamine tetraacetic acid sodium, sodium nitrilotriacetic acid, and aminotrimethylene phosphoric acid pentasodium.
As a preferred embodiment of the preparation according to the invention for disinfecting and hygienically cleaning hard surfaces of air conditioners and objects in general: also comprises pigment and/or essence; the paint comprises, by mass, 0-1 part of pigment and 0-1 part of essence.
As another aspect of the present invention, the present invention overcomes the disadvantages of the prior art by providing a method for preparing the formulation for disinfecting and sanitizing the hard surfaces of air conditioners and general objects.
In order to solve the technical problems, the invention provides the following technical scheme: the method of the preparation for air conditioning and general object hard surface disinfection and sanitation cleaning comprises the following steps,
adding water into a reaction kettle;
adding the chelating agent into a reaction kettle while stirring, stirring and heating, and controlling the temperature to be 30-70 ℃;
adding the active agent component;
adding the fatty alcohol, and fully stirring to completely and uniformly disperse the fatty alcohol;
adding the guanidine compound, and fully stirring to completely dissolve the guanidine compound;
adding the quaternary ammonium salt cationic compound to completely dissolve and uniformly disperse the quaternary ammonium salt cationic compound, and refluxing for 10-20 min;
accurately monitoring the temperature of the solution at 25 ℃ by using an acidimeter, and adjusting the pH value of the solution to be 5.0-8.0;
adding water, stirring uniformly, and refluxing for 10-20 min.
As a preferred embodiment of the process for the preparation of the preparations according to the invention for disinfecting and hygienically cleaning hard surfaces of air conditioners and objects in general: also comprises adding essence and/or pigment.
The invention has the beneficial effects that: the present invention is based on two cationic actives of different structure and nature: guanidine and quaternary ammonium salt active factor combination, complementary advantages, and the cross composite design of fatty alcohol, active agent and chelating agent, to form multiple active factor synergistic system, to generate excellent bactericidal bioactivity, better metal corrosion inhibition ability, improved stability, no toxicity and stimulation to human body, safety and environmental protection, to expand application field, to conveniently use in air-conditioning, food processing equipment, environment and general object surface disinfection and sanitation in household, hospital, hotel and other public places.
Detailed Description
In order to make the aforementioned objects, features and advantages of the present invention comprehensible, embodiments accompanied with examples are described in detail below.
In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention, but the present invention may be practiced in other ways than those specifically described and will be readily apparent to those of ordinary skill in the art without departing from the spirit of the present invention, and therefore the present invention is not limited to the specific embodiments disclosed below.
Furthermore, reference herein to "one embodiment" or "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment is included in at least one implementation of the invention. The appearances of the phrase "in one embodiment" in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments.
The disinfectant comprises the following components in parts by weight: 0.2-5 parts of quaternary ammonium salt cationic compound, 0.01-2 parts of guanidine compound, 0.1-1 part of chelating agent, 5-18 parts of fatty alcohol, 2-10 parts of active agent and the balance of water. The disinfectant is colorless or light yellow transparent liquid when pigment is not added, and the pH value of the solution is 5-8. After the preparation is finished, the method can be applied to the disinfection and cleaning of the surfaces of various general objects such as air conditioners, furniture, clothes, floors, bathrooms, pet raising environments and the like;
the quaternary ammonium salt cationic compounds include: one or more of dimethyl bisdodecyl ammonium chloride, dodecyl dimethyl ethylbenzene oxyethyl ammonium bromide, dimethyl bisdecyl ammonium chloride, dimethyl bisdecyl ammonium bromide, dimethyl bisdecyl ammonium carbonate, diethyl bisdodecyl ammonium carbonate, dimethyl bistetradecyl ammonium chloride, dimethyl bishexadecyl ammonium chloride, benzethonium chloride and benzethonium bromide are used as active ingredients.
The guanidine compound comprises one or more of polyhexamethylene biguanide or a derivative thereof and polyhexamethylene monoguanidine or a derivative thereof as an active ingredient.
The active agents include: one or a mixture of more than two of alkyl glycoside (alkyl carbon number is 8-10), propyl betaine, dodecyl betaine, fatty alcohol polyoxyethylene ether (AEO3), fatty alcohol polyoxyethylene ether (AEO9), cocamidopropyl amine oxide (CAO30), polyvinyl alcohol 400 and polyvinyl alcohol 600 is used as an active auxiliary component.
Fatty alcohols include: one or more of ethanol, ethylene glycol, propanol, isopropanol, propylene glycol, glycerol, butanol, and 1, 3-butanediol as solvent and synergist.
The chelating agent comprises: one or more than two of ethylene diamine tetraacetic acid, ethylene diamine tetraacetic acid disodium, ethylene diamine tetraacetic acid tetrasodium, ethylene diamine tetraacetic acid sodium, sodium nitrilotriacetic acid and aminotrimethylene phosphoric acid pentasodium are used as synergistic auxiliary materials.
Example 1:
weighing 16 parts of deionized water by mass, injecting the deionized water into a reactor, adding 0.2 part of ethylene diamine tetraacetic acid disodium under stirring, controlling the temperature at 40 ℃, after the dissolution is finished, adding 4 parts of fatty alcohol-polyoxyethylene ether (AEO9), adding 11 parts of propylene glycol, adding 0.20 part of polyhexamethylene biguanide under continuous stirring until the polyhexamethylene biguanide is completely dissolved, adding 5 parts of benzethonium chloride, refluxing for 20 minutes, accurately monitoring by using an acidimeter at the solution temperature of 25 ℃, and adjusting the pH value of the solution to be 5.0-7.5. Adding the rest 64 parts of deionized water, 1 part of essence and 1 part of pigment, stirring uniformly, and refluxing for 20 minutes to obtain a clear and transparent colorless liquid product.
Can be prepared into different preparation forms such as aerosol, spray, emulsion and the like according to different use purposes.
Example 2:
weighing 20 parts of deionized water by mass, injecting into a reaction kettle, adding 0.2 part of ethylene diamine tetraacetic acid under stirring, controlling the temperature at 35 ℃, after dissolution, adding 3 parts of polyvinyl alcohol (600), 12 parts of glycerol, adding 2 parts of polyhexamethylene guanidine ammonium carbonate under continuous stirring until the solution is completely dissolved, adding 4 parts of dodecyl dimethyl ethyl phenoxy ethyl ammonium bromide, refluxing for 20 minutes, accurately monitoring by using an acidimeter at the solution temperature of 25 ℃, and adjusting the pH value of the solution to be between 5.0 and 7.5. Adding the rest 60 parts of deionized water, 1 part of essence and 1 part of pigment, stirring uniformly, and refluxing for 10 minutes to obtain a clear and transparent colorless liquid.
Can be prepared into different preparation types such as aerosol, spray, emulsion and the like according to different use purposes.
Example 3:
1. adding 85 parts of deionized water into a reaction kettle by mass.
2. 0.1 part of EDTA4Na chelating agent was added to the kettle with stirring and the temperature was raised with stirring and controlled at 70 ℃.
3. 5 parts of CAO30 active ingredient are metered in with stirring.
4. 5 parts of glycerol are added with stirring, and the mixture is fully stirred to be completely and uniformly dispersed.
5. 0.01 part of polyhexamethylene biguanide hydrochloride compound which is accurately metered is added while stirring and fully stirred to be completely dissolved.
6. 0.2 part of diethylditetradecylalmmonium carbonate quaternary ammonium salt in an accurately measured amount is added while stirring to completely dissolve and uniformly disperse the ammonium carbonate quaternary ammonium salt. Refluxing for 15 min.
7. Accurately monitoring the temperature of the solution at 25 ℃ by using an acidimeter, and adjusting the pH value of the solution to be 5.0-7.0.
8. Add 0.4 parts of perfume, 0.6 parts of pigment and the rest 20 parts of deionized water, stir well, reflux for 15 min. The final product is a colorless or brownish yellow transparent liquid.
Example 4:
1. adding 20 parts of deionized water into a reaction kettle in parts by mass.
2. 0.1 part of EDTA4Na chelating agent was added to the kettle with stirring and the temperature was raised with stirring and controlled at 41 ℃.
3. 5 parts of CAO30 active ingredient are metered in with stirring.
4. 5 parts of glycerol are added with stirring, and the mixture is fully stirred to be completely and uniformly dispersed.
5. 0.01 part of polyhexamethylene biguanide hydrochloride compound which is accurately metered is added while stirring and fully stirred to be completely dissolved.
6. 0.2 part of diethylditetradecylalmmonium carbonate quaternary ammonium salt in an accurately measured amount is added while stirring to completely dissolve and uniformly disperse the ammonium carbonate quaternary ammonium salt. Refluxing for 15 min.
7. Accurately monitoring the temperature of the solution at 25 ℃ by using an acidimeter, and adjusting the pH value of the solution to be 5.0-7.0.
8. 0.4 part of perfume, 0.6 part of pigment and the rest 60 parts of deionized water are added, stirred uniformly and refluxed for 15 min. The final product is a colorless or brownish yellow transparent liquid.
The killing log values of the quaternary ammonium salt and guanidine active factor combination of the invention to indicator bacteria are shown in table 1. The R values of the test data for the corrosion rates of metals for different test active components for the combinations of active ingredients of table 1 are shown in table 2. The indicator bacteria killing logarithm values of the sterilization rate screening test after combining non-guanidine and quaternary ammonium salt or guanidine and non-quaternary ammonium salt active factors are shown in table 3.
TABLE 1 comparative analysis of killing log values of guanidine active factors and active factor combinations on indicator bacteria
1. Quantitative sterilization test according to 2002 edition suspension method of the sterilization technical specification of the ministry of health;
2. the contact time t is 1 min;
3. the other component was deionized water in the same proportions.
From the above table, it can be seen that the bactericidal activity of the compound is not enough and can not reach the national standard through test verification after quaternary ammonium salt is not added or other bactericidal active factors are added and are combined with guanidine active factors; preferred quaternary ammonium salts, in combination with a suitable guanidine or guanidine salt, result in excellent biocidal biological activity; the double-chain quaternary ammonium salt disinfectant structurally has 1 hydrophilic group and a plurality of hydrophobic groups, has better water solubility, organic matter dissolving and penetrating capability, good capability of reducing the surface tension of a solution, negative effects of resisting anion activity, hard water, protein organic matters and the like, and few foams. The water solubility is excellent, the influence of water quality is avoided, and the antibacterial spectrum is widened while the good sterilization effect is maintained. Quaternary ammonium salt, guanidine and their salts have positive charges after hydrolysis in water, are adsorbed on the surface of microorganisms to form ion micelles, and gradually permeate into lipid layers and protein layers of cytoplasm, so that the permeability of cell membranes is changed, the cell contents are caused to permeate outwards, and the cells are killed. At the same time, cell protein is coagulated, biological enzyme and structural protein of bacteria are denatured, metabolism of the microorganisms is destroyed, cytoplasmic protein and cell membrane are precipitated, the bacteria cannot normally survive, and finally the microorganisms are killed. The standard of the national ministry of health for killing pathogenic microorganisms by a suspension method is that the killing logarithm value of large intestine and pseudomonas aeruginosa is required to be more than 5; and the product can be judged to be qualified after the white idea is more than 4.
Table 2 shows the R values of the test data of the corrosion rates of different test active components to metals
1. The detection basis is as follows: disinfection Specification (2002 edition) 2.2.4.
2. Detection materials: carbon steel (specification is GB 700-65); copper (specification in GB 2060-80); aluminum (specification see GB 1173-74); stainless steel (specification see GB 1220-75). The metal sheet is immersed in the solution and hermetically soaked 72Hrs and the corrosion rate is calculated by treating and weighing the metal sheet.
3. The national standard R <0.0100 basically has no corrosion; 0.0100< R <0.100 mild corrosion; 0.100< R <1.00 moderate corrosion; r >1.00 severe corrosion.
TABLE 3 log kill of non-guanidines in combination with quaternary ammonium salts or guanidines in combination with non-quaternary ammonium salt active factors
1, performing quantitative sterilization test according to a 2002 suspension method of the disinfection technical specification of the ministry of health;
the contact time t is 1 min;
2. the other component was the same deionized water.
As can be seen from the above table, no guanidines, or other bactericidal activity factors in combination with quaternary ammonium salts are added; or adding a new active agent and the active combination of guanidine, and the test result shows that the bactericidal activity of the composition is insufficient and can not reach the national standard; the test data demonstrate that the combination of the preferred guanidines with a portion of the preferred quaternary ammonium salts in a reasonable ratio results in superior germicidal activity.
TABLE 4 analysis of kill log impact data for combinations of quaternary ammonium salts and guanidine active agents with different active agents
As can be seen from the above table, no or other different surface activities have significant effects on the combination of guanidine and quaternary ammonium salt bactericidal active factors, which may cause insufficient bactericidal activity and fail to meet the national standard, because part of the surface activities may have adsorption or encapsulation effects on functional groups of cationic active agents and the whole molecule, and severely restrict and restrict the bactericidal activity of the bactericidal active factors; preferred epiactive guadine and quaternary ammonium salt active agents in combination result in excellent bactericidal biological activity; the mechanism is that proper surface activity is added to generate a complementary combination effect with the chemical structure of the bactericidal factor, on one hand, the dissolving and dispersing capacity of the bactericidal factor in water is enhanced, on the other hand, the proper surface activity can promote the adsorption and permeation of the bactericidal factor on the cell surface and the permeation capacity, and is beneficial to the development attack and the influence of the bactericidal factor on organs inside pathogenic bacteria; and judging the qualification if the white idea is more than 4.
TABLE 5 test data for the effect of alcohol, chelating agent on the combined killing log of quaternary ammonium salt and guanidine active factors
Through the comparison design of biguanide \ quaternary ammonium salt active components and biguanide \ non-quaternary ammonium salt and other active combination systems, the biological activity and the bactericidal activity combination comparison design without adding surface activity or adding other surface activity and guanidine, quaternary ammonium salt and the like are measured through the crossed practical test of adding different surface activities, alcohols, chelating agents and other components, and the results of the systematic test research judge that the bactericidal activity is insufficient and can not reach the national standard; the preferred surfactant pair guanidine and quaternary ammonium salt combination can generate excellent bactericidal biological activity; the mechanism is that the addition of proper surface activity can have complementary combined effect with the chemical structure of the bactericidal factor, on one hand, the dissolving and dispersing capacity of the bactericidal factor in water is enhanced, and on the other hand, the proper surface activity can promote the adsorption and permeation of the bactericidal factor on the cell surface and the permeation capacity of the bacterial cell membrane, thereby being beneficial to the development attack of the bactericidal factor on the internal structural tissues of pathogenic bacteria. The third mechanism is that the side effect of organic matters such as anion active agent, hard water, protein and the like is added properly, so that the water solubility and fat-soluble dispersing ability are enhanced, and the overall efficacy which is not influenced by water quality is improved; the chelating agent and the optimized surfactant/cationic active agent can be combined to form high bactericidal activity and stably enhance corrosion inhibition capability, and the mechanism is that auxiliary agent molecules in the solution can form a film on the surfaces of metals and the like to influence the generation of polarization phenomenon, so that the microbial propagation on the surface of an object can be controlled for a long time, and the corrosion of metal materials can be prevented, which is also a new finding of our test; the chelating agent can complex calcium and magnesium ions to a certain extent, has an inhibiting effect on the biological activity of bacterial enzymes, and assists bactericidal factors to enhance the bactericidal effect, which is a new discovery through a large number of experiments.
TABLE 6 test set of corresponding test group disinfectant solution to metal corrosion rate test data R values prepared by laboratory process
From the above table, it can be seen that the addition of a suitable amount of polyhexamethylene biguanide in combination with a suitable amount of bis-long-chain quaternary ammonium salt, a surfactant and an auxiliary agent in a ratio reduces the corrosion rate of the metal and can result in excellent corrosion inhibition capability of the metal.
TABLE 7 results of tests for disinfecting the surface of an object with preferred composition formulations
The sterilization time t is 1min according to the technical specification of the disinfectant of the ministry of health.
TABLE 8 Primary irritation response to Rabbit skin score
The hygienic disinfection is performed by analyzing the data of one-time stimulation response to the rabbit skin, and the rabbit skin is not stimulated.
Toxicology test results:
1. samples for oral LD in female mice50(95% confidence limit) 4300(2950-6260) mg/kgb. wt. belonging to low toxicity level; samples were orally LD to male mice50(95% confidence limit) is 5840 (4300-;
2. 5 times of solution with the highest application concentration for female and male mice to take oral LD50The values are all more than 5000mg/kgb.wt., which is actual non-toxic;
3. mouse marrow pleochromocyte micronucleus test:
the tested dosage of the male and female mice respectively reaches 2150 and 2929mg/kgb.wt, and no micronucleus effect of the sample on the myeloadephagia pleochromocyte of the mice is detected.
The invention forms a multiple active factor and a synergistic system through the combination of two cationic active substances guanidine and quaternary ammonium salt active factors with different structures and properties, the complementary advantages and the cross composite design of fatty alcohol, an active agent and a chelating agent, so that the multi-active factor and synergistic system has excellent bactericidal bioactivity and metal corrosion inhibition capability, simultaneously has improved stability, reduced toxicity, safety and reliability to human bodies and environmental protection, and the product and the technology are mainly applied to the disinfection and sanitary cleaning of air conditioners, food processing equipment, environments and the surfaces of general objects in public places such as families, hospitals, hotels and the like.
The composition stock solution has high-efficiency bioactivity, has high efficiency on gram-negative and gram-positive pathogenic bacteria and fungi, has the biological activity characteristics of wide bactericidal spectrum and high killing speed shown by microbial tests, realizes quick sterilization in 1 minute, provides quick functional service for users, and has the efficacy far exceeding that of similar products; the liquid product can be prepared into spray, aerosol, emulsion and true solution systems, and shows the practical effect, convenience, high efficiency and economic advantages of the use of the invention.
All materials are the most safe and environment-friendly raw materials, are non-toxic and non-irritating to human beings, can be quickly degraded in the nature, belong to environment-friendly products, can be directly applied to the safety and sanitation levels of disinfection and cleaning of air conditioners for families and hospitals, surfaces of food production equipment and furniture, and cannot achieve the effect or be compared with the effect of common disinfectants.
The invention adopts the most advanced innovative design of crossing the quaternary ammonium cation compound and the biguanide compound with environmental protection and high safety, makes up the respective lack of biological activity of the quaternary ammonium cation compound and the biguanide compound, generates strong synergistic effect according to the test result, enhances the biological activity, thereby forming the characteristic of wide bactericidal spectrum and having high efficiency on fungi, which is the advantage of the invention in the prior art compared with other disinfectants with single bactericidal active component. Meanwhile, through a preparation system with cross compatibility, the test result proves the enhancement of the metal corrosion inhibition capability, which shows the final effect of low corrosion rate after the preparation is soaked in various metal samples. The preferable active combination design of the surfactant and the fatty alcohol is combined with the quaternary ammonium salt cation and the guanidine activity, so that the integral effect of the multiple active combination of mutually-assisted and mutually-promoted sterilization and cleaning and metal preservation is formed, and an innovative preparation system is formed.
In addition, the system can eliminate the static electricity of clothes, soften the clothes and has no oxidation, decoloration and denaturation effects on the clothes; the disinfectant has the advantages of extremely low corrosivity on metals, no stimulation to human skin, multiple effects of machine washing and hand washing, capability of killing pathogenic candida albicans, effective removal of pathogen transmission media, no cross infection, and safer and more reliable use process than other similar products.
The bactericidal active ingredient of the preparation has good stability in the preparation system, the quality guarantee period is more than 24-36 months, the bactericidal active ingredient is not degraded, is not easy to discolor, and has the characteristics of stability, reliability and contribution to long-term storage and transportation which are superior to the technology of other similar products.
It should be noted that the above-mentioned embodiments are only for illustrating the technical solutions of the present invention and not for limiting, and although the present invention has been described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions may be made on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention, which should be covered by the claims of the present invention.
Claims (2)
1. A preparation for disinfection and hygienic cleaning of air-conditioning and general objects hard surfaces, characterized in that: the composition comprises the following components in parts by mass: 0.2 part of diethyl ditetradecyl ammonium carbonate, 0.01 part of polyhexamethylene biguanide hydrochloride, 5 parts of oxidized cocamidopropyl amine, 5 parts of glycerol, 0.1 part of EDTA-4Na, 0.4 part of perfume, 0.6 part of pigment and 80 parts of deionized water.
2. A process for the preparation of a formulation according to claim 1 for the disinfection and hygienic cleaning of hard surfaces of air conditioners and objects in general, characterized in that: the method comprises the following steps of (1),
(1) adding 20 parts of deionized water into a reaction kettle in parts by mass;
(2) adding 0.1 part of EDTA-4Na chelating agent into the reaction kettle under stirring, stirring and heating, and controlling the temperature at 41 ℃;
(3) adding 5 parts of an oxidized cocoamidopropyl amine active agent while stirring;
(4) adding 5 parts of glycerol while stirring, and fully stirring to completely and uniformly disperse the glycerol;
(5) adding 0.01 part of polyhexamethylene biguanide hydrochloride compound while stirring, and fully stirring to completely dissolve the polyhexamethylene biguanide hydrochloride compound;
(6) adding 0.2 part of diethyl ditetradecyl ammonium carbonate quaternary ammonium salt while stirring to completely dissolve and uniformly disperse the ammonium salt, and refluxing for 15 min;
(7) accurately monitoring the temperature of the solution at 25 ℃ by using an acidimeter, and adjusting the pH value of the solution to 5.0-7.0;
(8) 0.4 part of perfume, 0.6 part of pigment and 60 parts of deionized water are added, stirred uniformly and refluxed for 15 min.
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| CN111073772A (en) * | 2019-12-17 | 2020-04-28 | 河南绿澳化工科技有限公司 | Air conditioner cleaning agent and preparation method thereof |
| CN111642512A (en) * | 2020-03-12 | 2020-09-11 | 天天向上(宁波)医疗科技有限公司 | High-efficiency disinfectant and preparation method and use method thereof |
| CN111493073A (en) * | 2020-05-28 | 2020-08-07 | 李学军 | Surface disinfection film covering agent and preparation method thereof |
| CN111771886A (en) * | 2020-08-20 | 2020-10-16 | 开平市美康泉生物科技有限公司 | Double-long-chain compound quaternary ammonium salt disinfectant for indoor and air-conditioning ventilation systems |
| CN114246180A (en) * | 2020-09-24 | 2022-03-29 | 湖南五指峰生化有限公司 | Foam cleaning disinfectant and preparation method thereof |
| CN113136040B (en) * | 2021-05-08 | 2022-07-19 | 中国科学院华南植物园 | Cationic starch gel and preparation method and application thereof |
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