CN109718246A - A kind of nasal cavity cleaning liquid - Google Patents
A kind of nasal cavity cleaning liquid Download PDFInfo
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- CN109718246A CN109718246A CN201910122837.6A CN201910122837A CN109718246A CN 109718246 A CN109718246 A CN 109718246A CN 201910122837 A CN201910122837 A CN 201910122837A CN 109718246 A CN109718246 A CN 109718246A
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- nasal cavity
- cleaning liquid
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- cavity cleaning
- inflammatory
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Abstract
The invention discloses a kind of nasal cavity cleaning liquid, which is comprised the following components in parts by weight: 0.5-2.0 parts of electrolyte, 0.05-0.15 parts of buffer salt, native compound 0.00002-0.01 parts and 75-100 parts of pure water anti-inflammatory.Cleaning nursing is carried out to nasal cavity using cleaning solution of the invention, allergic symptom can not only be mitigated, and pure natural components are mildly non-stimulated, is conducive to the recovery and self-healing of environment in nasal cavity.
Description
Technical field
The present invention relates to nasal cavity cleaning liquid technical fields, and in particular to a kind of nasal cavity cleaning liquid.
Background technique
With the aggravation of air pollution, the disease incidence such as rhinitis, nasosinusitis and nasopharyngitis persistently rise.Contain in urban air
Dust, indusrial toxic gas, vehicle exhaust etc. can increase the respiratory diseases such as rhinitis, nasosinusitis, allergic rhinitis
Occur.For environmental stimuli, nasal cavity can generate secretion to remove the harmful substance of sucking, but when human body nasal cavity can not will continue
When the allergy or harmful components of sucking are excluded or removed, nasal cavity cleaning product will be helpful to remove harmful components or allergic component.
Can effectively clean at present nasal cavity and treat nosal inflammation disease all-natural product there are also to be developed.
Summary of the invention
The purpose of the present invention is to provide a kind of nasal cavity cleaning liquid, containing natural anti-in nasal cavity cleaning liquid provided by the invention
Scorching substance can effectively clean nasal cavity and treatment nosal inflammation disease.
The present invention solves its technical problem and adopts the following technical solutions to realize.
The invention proposes a kind of nasal cavity cleaning liquid, comprise the following components in parts by weight: 0.5-2.0 parts of electrolyte, buffering
It is 0.05-0.15 parts of salt, native compound 0.00002-0.01 parts and 75-100 parts of pure water anti-inflammatory.
The present invention also proposes a kind of preparation method of above-mentioned nasal cavity cleaning liquid, comprising the following steps: by electrolyte, buffer salt
And anti-inflammatory native compound mixes in proportion, and is added to the water and sufficiently dissolves at room temperature, nasal cavity cleaning liquid is made.
The beneficial effects of the present invention are:
The present invention provides a kind of nasal cavity cleaning liquid, carry out cleaning nursing to nasal cavity using cleaning solution of the invention, not only
Allergic symptom can be mitigated, and pure natural components are mildly non-stimulated, be conducive to the recovery and self-healing of various people's environment in nasal cavity.
Specific embodiment
It in order to make the object, technical scheme and advantages of the embodiment of the invention clearer, below will be in the embodiment of the present invention
Technical solution be clearly and completely described.The person that is not specified actual conditions in embodiment, according to normal conditions or manufacturer builds
The condition of view carries out.Reagents or instruments used without specified manufacturer is the conventional production that can be obtained by commercially available purchase
Product.
A kind of nasal cavity cleaning liquid provided in an embodiment of the present invention is specifically described below.
The embodiment of the present invention provides a kind of nasal cavity cleaning liquid, comprises the following components in parts by weight: 0.5-2.0 parts of electrolyte,
It is 0.05-0.15 parts of buffer salt, native compound 0.00002-0.01 parts and 75-100 parts of pure water anti-inflammatory.
The embodiment of the present invention provides a kind of nasal cavity cleaning liquid, comprises the following components in parts by weight: 0.5-2.0 parts of electrolyte,
It is 0.05-0.15 parts of buffer salt, native compound 0.00002-0.01 parts and 75-100 parts of pure water anti-inflammatory.The work of electrolyte
Keep the osmotic pressure of cleaning solution and physiological condition (0.9% sodium chloride) close with being, thus achieve the effect that it is mild non-stimulated, therefore
The electrolyte dissolution of 0.5-2.0 parts of selection is in 75-100 parts of water.The effect of buffer salt is the pH and physiological condition for making cleaning solution
(neutral pH) is close, to achieve the effect that mild non-stimulated, stable buffer solution, selects 0.05-0.15 parts in order to obtain
Buffer salt be dissolved in 75-100 parts of water.The effect of anti-inflammatory native compound is to inhibit the inflammation of nasal cavity, it is contemplated that its is water-soluble
Property and effective concentration and price, select 0.00002-0.01 parts of anti-inflammatory native compound.Since all the components are pure natural
Compound does not have irritation and side effect to children and old man, target user is extensive without chemistry or biopharmaceutical ingredients.
In some embodiments, which comprises the following components in parts by weight: 0.9-1.5 parts of electrolyte delays
Rush 0.08-0.12 parts of salt, native compound 0.001-0.004 parts and 90-100 parts of pure water anti-inflammatory.
In some embodiments, which comprises the following components in parts by weight: 1.3 parts of electrolyte, buffer salt
0.1 part, 0.002 part of anti-inflammatory native compound and 97 parts of pure water.
In some embodiments, electrolyte includes sodium chloride.
In some embodiments, buffer salt includes at least two twisted in lemon acid, sodium citrate and sodium bicarbonate.
In some embodiments, anti-inflammatory native compound includes glycyrrhizin, isoliquiritigenin, glycyrrhizic acid and isoliquiritin
At least one of.
Above-mentioned glycyrrhizin, isoliquiritigenin, glycyrrhizic acid and isoliquiritin structural formula be shown below:
These types of compound is the extract in Radix Glycyrrhizae.Radix Glycyrrhizae also known as Herba Hedyotis cantonensis have clearing heat and detoxicating, moistening lung to arrest cough, tune
The effect of with all medicines.Radix Glycyrrhizae is very widely used, has Radix Glycyrrhizae to be used as medicine in many prescriptions of traditional Chinese medicine.Modern pharmacology research table
Bright, Radix Glycyrrhizae has liver protection, anti-inflammatory, antiviral and antitumor, anti-arrhythmia, adjusts a variety of effects such as immunity.Flavones and triterpene
Saponin component is the main active in Radix Glycyrrhizae.Wherein, glycyrrhizic acid and enoxolone are most important in generally acknowledged Radix Glycyrrhizae
Active constituent.And glycyrrhizin, isoliquiritigenin and its corresponding glycosides compound are the highest flavones ingredients of content, and are also had
There is the pharmacological activity of highly significant.Therefore, nasal cavity cleaning liquid provided in an embodiment of the present invention has finally chosen glycyrrhizin, different Radix Glycyrrhizae
Element, glycyrrhizic acid and isoliquiritin are as anti-inflammatory component.
The embodiment of the present invention also provides a kind of preparation method of above-mentioned nasal cavity cleaning liquid, comprising the following steps: by electrolyte,
Buffer salt and anti-inflammatory native compound mix in proportion, and are added to the water and sufficiently dissolve at room temperature, it is clear to obtain nasal cavity
Washing lotion.
In some embodiments, the pH of nasal cavity cleaning liquid is controlled in 6.5-7.5.
In some embodiments, 50%- of the osmotic pressure control of nasal cavity cleaning liquid in physiological condition osmotic pressure
160%.
In some embodiments, above-mentioned nasal cavity cleaning liquid is made i.e. with liquid, be perhaps made concentrated liquid or
Solid mixture is made, then by user face the used time by provided formula be added appropriate amounts of sterilized water and be configured to i.e. with more function
It can nasal cavity cleaning liquid.
Feature and performance of the invention are described in further detail with reference to embodiments.
Embodiment 1
A kind of preparation method of nasal cavity cleaning liquid, comprising the following steps:
With pure water and various raw materials by following weight ratio addition container: 400 grams of pure water, 5.65 grams of sodium chloride, carbonic acid
0.277 gram of hydrogen sodium, 0.045 gram of citric acid, 0.125 gram of sodium citrate, sufficiently dissolution is then mixed, adjustment pH value of solution is 6.9,
Prepare 400 milliliters of nasal cavity cleaning liquid.
Embodiment 2
A kind of preparation method of nasal cavity cleaning liquid, comprising the following steps:
With pure water and various raw materials by following weight ratio addition container: 400 grams of pure water, 5.64 grams of sodium chloride, carbonic acid
0.27 gram of hydrogen sodium, 0.12 gram of sodium citrate, 0.04 gram of citric acid, 0.008 gram of glycyrrhizin, sufficiently dissolution is then mixed, is adjusted molten
Liquid pH is 6.9, prepares 400 milliliters of nasal cavity cleaning liquid.
Embodiment 3
With pure water and various raw materials by following weight ratio addition container: 400 grams of pure water, 5.64 grams of sodium chloride, carbonic acid
0.27 gram of hydrogen sodium, 0.12 gram of sodium citrate, 0.04 gram of citric acid, 0.008 gram of isoliquiritigenin, then mix sufficiently dissolution, adjustment
PH value of solution is 7.0, prepares 400 milliliters of nasal cavity cleaning liquid.
Embodiment 4
With pure water and various raw materials by following weight ratio addition container: 400 grams of pure water, 5.64 grams of sodium chloride, carbonic acid
0.27 gram of hydrogen sodium, 0.12 gram of sodium citrate, 0.04 gram of citric acid, 0.008 gram of isoliquiritin, then mix sufficiently dissolution, adjustment
PH value of solution is 7.0, prepares 400 milliliters of nasal cavity cleaning liquid.
Embodiment 5
With pure water and various raw materials by following weight ratio addition container: 400 grams of pure water, 5.64 grams of sodium chloride, carbonic acid
0.27 gram of hydrogen sodium, 0.12 gram of sodium citrate, 0.04 gram of citric acid, 0.008 gram of glycyrrhizic acid, sufficiently dissolution is then mixed, is adjusted molten
Liquid pH is 7.0, prepares 400 milliliters of nasal cavity cleaning liquid.
Embodiment 6
The application example of nasal cavity cleaning liquid in above embodiments 1-5:
Four bit length phases after the knowledge that the cook of rear kitchen cooking has understood pure natural nasal cavity cleaning liquid, were agreed on probation by implementing
Cleaning solution made by example 1 carries out nasal nursing, and the oil smoke sucked in nasal cavity and secretion are cleaned out.After use they
Dirt in nasal cavity disappears, and nose smell is sensitiveer, all pleases oneself to the effect of pure natural nasal cavity cleaning liquid.
Two traffic-polices have learnt the knowledge in relation to pure natural nasal cavity cleaning liquid, it has been agreed that on probation by 2 institute of embodiment
The cleaning solution of production carries out nasal nursing.Due on duty outdoors for a long time, the nasal cavity of this two traffic police have more secretion with
Dust is wrapped up, pure natural nasal cavity cleaning liquid is After Hours commonly used and nasal cavity is nursed, nasal cavity becomes cleaner, breathes more suitable
Freely.
Two have the university student of allergic rhinitis often to have a running nose in Changes in weather, they have read related pure natural nose
The cleaning solution on probation as made by embodiment 2 is agreed to after chamber cleaning solution data, the trial employment period is through common watering can hydro-peening nasal cavity, nose
It is dredged, symptom snotty is mitigated.
Above 8 volunteers are made of 4 males and 4 women, and age distribution is between -70 years old 20 years old.Volunteer is equal
There is not adverse reaction, the irritative responses such as sneezing, rhinorrhea do not occur, therefore the incidence of adverse reaction is 0%,
This has the characteristics that safe, mild statistics indicate that nasal cavity cleaning liquid of the invention does not have irritation to mid-aged population.
Nasal cavity cleaning liquid provided in an embodiment of the present invention is suitable for rhinitis and sinusitis in patients and the work under poor environment
The special occupation crowd of work.Cleaning nursing is carried out to nasal cavity using cleaning solution provided by the invention, allergic symptom can not only be mitigated,
And pure natural components are mildly non-stimulated, are conducive to the recovery and self-healing of various people's environment in nasal cavity.Therefore, the embodiment of the present invention
The nasal cavity cleaning liquid of offer has good market prospects and popularizing value.
As it can be seen that the embodiment of the present invention provides a kind of nasal cavity cleaning liquid, comprise the following components in parts by weight: electrolyte 0.5-
2.0 parts, it is 0.05-0.15 parts of buffer salt, native compound 0.00002-0.01 parts and 75-100 parts of pure water anti-inflammatory.This hair
Nasal cavity cleaning liquid in bright embodiment is reference with the physiological environment of human body and environment in nasal cavity, by water, electrolyte, buffer salt and pure
Natural anti-inflammatory compound carries out rational proportion, and pure natural nasal cavity cleaning liquid is made.The characteristics of these cleaning solutions are as follows: the acid with nasal cavity
Basicity and osmotic pressure are consistent, mild non-stimulated；It is able to maintain the wet of environment in nasal cavity；With in removing nasal cavity, nasal sinus and nasopharynx
The function of pollutant and secretion；Have the function of dredging nasal cavity and then improves breathing quality；Can gradually eliminate nose allergy and
Inflammatory reaction.
The crowd that cleaning solution in the embodiment of the present invention is applicable in is the people for needing to clean nasal cavity, especially rhinitis and nasal sinus
Scorching patient and dust suck more crowd, such as fire fighter, traffic police, sweeper and cement, coal industry worker.Nasal surgery
Patient afterwards can be used the cleaning solution and nasal cavity and nasal sinus effectively cleaned and nursed.Anaphylactogen in environment is generated
The crowd of allergy and inflammatory reaction can be used the cleaning solution and be nursed nasal cavity to mitigate allergy and inflammatory symptom.
Embodiments described above is a part of the embodiment of the present invention, instead of all the embodiments.Reality of the invention
The detailed description for applying example is not intended to limit the range of claimed invention, but is merely representative of selected implementation of the invention
Example.Based on the embodiments of the present invention, obtained by those of ordinary skill in the art without making creative efforts
Every other embodiment, shall fall within the protection scope of the present invention.
Claims (10)
1. a kind of nasal cavity cleaning liquid, which is characterized in that comprise the following components in parts by weight: 0.5-2.0 parts of electrolyte, buffer salt
0.05-0.15 parts, it is native compound 0.00002-0.01 parts and 75-100 parts of pure water anti-inflammatory.
2. nasal cavity cleaning liquid according to claim 1, which is characterized in that comprise the following components in parts by weight: electrolyte
0.9-1.5 parts, it is 0.08-0.12 parts of buffer salt, native compound 0.001-0.004 parts and 90-100 parts of pure water anti-inflammatory.
3. nasal cavity cleaning liquid according to claim 2, which is characterized in that comprise the following components in parts by weight: electrolyte 1.3
Part, 0.1 part of buffer salt, 0.002 part of anti-inflammatory native compound and 97 parts of pure water.
4. nasal cavity cleaning liquid according to claim 1-3, which is characterized in that the electrolyte includes sodium chloride.
5. nasal cavity cleaning liquid according to claim 1-3, which is characterized in that the buffer salt include twist lemon acid,
At least two in sodium citrate and sodium bicarbonate.
6. nasal cavity cleaning liquid according to claim 1-3, which is characterized in that the anti-inflammatory native compound includes
At least one of glycyrrhizin, isoliquiritigenin, glycyrrhizic acid and isoliquiritin.
7. a kind of preparation method of nasal cavity cleaning liquid according to claim 1-6, which is characterized in that including following
Step: the electrolyte, the buffer salt and the anti-inflammatory native compound are mixed in proportion, are added in the water simultaneously
Sufficiently dissolution at room temperature, is made the nasal cavity cleaning liquid through aseptic packaging.
8. the preparation method of nasal cavity cleaning liquid according to claim 7, which is characterized in that the pH of the nasal cavity cleaning liquid is controlled
System is in 6.5-7.5.
9. the preparation method of nasal cavity cleaning liquid according to claim 7, which is characterized in that the infiltration of the nasal cavity cleaning liquid
50%-160% of the voltage-controlled system in physiological condition osmotic pressure thoroughly.
10. -9 described in any item nasal cavity cleaning liquid according to claim 1, which is characterized in that the nasal cavity cleaning liquid to be made
Liquid is used, concentrated liquid is perhaps made or solid mixture is made, the used time is then faced by provided formula by user
Appropriate amounts of sterilized water is added and is configured to i.e. with functional nasal cleaning solution.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910122837.6A CN109718246A (en) | 2019-02-19 | 2019-02-19 | A kind of nasal cavity cleaning liquid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910122837.6A CN109718246A (en) | 2019-02-19 | 2019-02-19 | A kind of nasal cavity cleaning liquid |
Publications (1)
| Publication Number | Publication Date |
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| CN109718246A true CN109718246A (en) | 2019-05-07 |
Family
ID=66300554
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910122837.6A Pending CN109718246A (en) | 2019-02-19 | 2019-02-19 | A kind of nasal cavity cleaning liquid |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112691118A (en) * | 2021-02-25 | 2021-04-23 | 河南比福制药股份有限公司 | Disinfectant for rhinitis |
| CN113975223A (en) * | 2021-08-06 | 2022-01-28 | 华中科技大学 | Nasal cavity cleaning solution |
| WO2022110619A1 (en) * | 2020-11-26 | 2022-06-02 | 江苏泰德医药有限公司 | Product and preparation method for prevention and treatment of novel coronavirus |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63156728A (en) * | 1986-12-19 | 1988-06-29 | Eisai Co Ltd | Aqueous solution pharmaceutical containing lysozyme chloride and dipotassium glycyrrhetinate |
| CN102204926A (en) * | 2011-05-31 | 2011-10-05 | 江苏富林医疗设备有限公司 | Nasal cavity cleaning agent |
-
2019
- 2019-02-19 CN CN201910122837.6A patent/CN109718246A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63156728A (en) * | 1986-12-19 | 1988-06-29 | Eisai Co Ltd | Aqueous solution pharmaceutical containing lysozyme chloride and dipotassium glycyrrhetinate |
| CN102204926A (en) * | 2011-05-31 | 2011-10-05 | 江苏富林医疗设备有限公司 | Nasal cavity cleaning agent |
Non-Patent Citations (2)
| Title |
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| 吴敏曼等: "甘草提取物防治变应性鼻炎的实验研究", 《中国民族民间医药》 * |
| 张明发等: "甘草及其活性成分抗炎与抗炎机制的研究进展", 《现代药物与临床》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022110619A1 (en) * | 2020-11-26 | 2022-06-02 | 江苏泰德医药有限公司 | Product and preparation method for prevention and treatment of novel coronavirus |
| CN112691118A (en) * | 2021-02-25 | 2021-04-23 | 河南比福制药股份有限公司 | Disinfectant for rhinitis |
| CN113975223A (en) * | 2021-08-06 | 2022-01-28 | 华中科技大学 | Nasal cavity cleaning solution |
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Application publication date: 20190507 |