CN109704258A - A kind of filling Aerating needle and packaging process - Google Patents
A kind of filling Aerating needle and packaging process Download PDFInfo
- Publication number
- CN109704258A CN109704258A CN201910023515.6A CN201910023515A CN109704258A CN 109704258 A CN109704258 A CN 109704258A CN 201910023515 A CN201910023515 A CN 201910023515A CN 109704258 A CN109704258 A CN 109704258A
- Authority
- CN
- China
- Prior art keywords
- filling
- needle
- bottle body
- needle tubing
- aeration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000012858 packaging process Methods 0.000 title claims abstract description 15
- 238000005273 aeration Methods 0.000 claims abstract description 46
- 239000003814 drug Substances 0.000 claims abstract description 17
- 229940079593 drug Drugs 0.000 claims abstract description 15
- 239000011261 inert gas Substances 0.000 claims abstract description 13
- 239000007788 liquid Substances 0.000 claims abstract description 10
- 238000007789 sealing Methods 0.000 claims abstract description 8
- 239000007789 gas Substances 0.000 claims description 7
- 239000012530 fluid Substances 0.000 abstract description 18
- 239000000126 substance Substances 0.000 description 9
- 238000010586 diagram Methods 0.000 description 7
- 230000006872 improvement Effects 0.000 description 6
- 239000007921 spray Substances 0.000 description 6
- 230000008859 change Effects 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 238000005538 encapsulation Methods 0.000 description 4
- 239000003708 ampul Substances 0.000 description 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 3
- 238000003286 fusion draw glass process Methods 0.000 description 3
- 230000003434 inspiratory effect Effects 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 239000001301 oxygen Substances 0.000 description 3
- 229910052760 oxygen Inorganic materials 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 238000007664 blowing Methods 0.000 description 2
- 238000010276 construction Methods 0.000 description 2
- 238000006392 deoxygenation reaction Methods 0.000 description 2
- 230000005484 gravity Effects 0.000 description 2
- 238000002844 melting Methods 0.000 description 2
- 230000008018 melting Effects 0.000 description 2
- 238000004806 packaging method and process Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 238000005245 sintering Methods 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000004927 fusion Effects 0.000 description 1
- 238000003754 machining Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
Landscapes
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Vacuum Packaging (AREA)
- Basic Packing Technique (AREA)
Abstract
The invention discloses a kind of filling Aerating needle, including needle tubing, multiple aeration apertures are offered on the tube wall of the needle tubing, the aeration aperture is arranged diagonally downward, along the axial direction of the needle tubing, has spacing between at least two aeration apertures.The present invention further discloses a kind of packaging process, comprising the following steps: inert gas S1, filling preceding inflation: is filled in bottle body；S2, filling: filling needle enters liquid drug in bottle body；S3, filling rear inflation: inert gas is filled in bottle body using filling Aerating needle above-mentioned；S4, the sealing of bottle body melt drawing.The advantages that present invention has structure simple, is conducive to blow off the remaining medical fluid of bottleneck inner wall, guarantees the drug quality after encapsulating.
Description
Technical field
The present invention relates to food, medicine packaging machinery and method more particularly to a kind of filling Aerating needles and packaging process.
Background technique
Medical fluid needs to be filled with inert gas in bottle after pouring into Packaging Bottle, reduces oxygen content in bottle body, prevents from sealing
Oxidation of drug in bottle body afterwards, to enhance shelf lives.The main method inflated at present is using Aerating needle to being filled in bottle body
Inert gas (common such as nitrogen), but Aerating needle air-flow is excessive sometimes that liquid level in bottle body is easy to cause to splash, medical fluid attachment
In bottle wall, filling quality is influenced；On the other hand, when progress medical fluid is filling, medical fluid is also possible to remain on bottle body bottleneck,
Especially when filling to ampoule bottle progress medical fluid, since ampoule bottle-neck is elongated, medical fluid is particularly easy to remain in bottleneck inner wall,
When carrying out high-temperature fusion drawing seal after filling, the medical fluid that bottleneck remains in bottleneck inner wall during high temperature sintering can generation
Variation is learned, while ampoule bottle sealing part is easy to cover because of the substance of high temperature sintering generation black on surface, after largely effecting on encapsulation
Drug quality.Aerating needle lower end air-flow is excessive in order to prevent causes liquid level to splash, while utilizing air-flow by the medicine of bottleneck inner wall
Liquid is blown off, and existing Aerating needle mostly opens up aeration aperture, aeration aperture axis horizontal arrangement on the tube wall of needle tubing.This structure
Aeration aperture gas can not spray, and can generate negative inspiratory pressure phenomenon on the contrary, cause anti-liquid level to splash effect unobvious, can not be true
Guarantor blows off the remaining medical fluid of bottleneck inner wall.
Summary of the invention
The technical problem to be solved by the present invention is to overcome the deficiencies in the prior art, it is simple to provide a kind of structure, be conducive to by
The filling Aerating needle that the remaining medical fluid of bottleneck inner wall is blown off.
The present invention further provides a kind of packaging process.
In order to solve the above technical problems, the invention adopts the following technical scheme:
A kind of filling Aerating needle, including needle tubing offer multiple aeration apertures on the tube wall of the needle tubing, and the aeration aperture is inclined
It is arranged obliquely, along the axial direction of the needle tubing, there is spacing between at least two aeration apertures.
As a further improvement of the above technical scheme: there are three the aeration aperture is set, along the axis projection of the needle tubing,
Three aeration apertures are evenly arranged in 120 ° of angles.
As a further improvement of the above technical scheme: the folder between the axis of the aeration aperture and the axis of the needle tubing
Angle is β, then 20 °≤β≤70 °.
As a further improvement of the above technical scheme: β=30 °.
As a further improvement of the above technical scheme: the needle tubing is hollow structure.
As a further improvement of the above technical scheme: the axial spacing between the aeration aperture is L1, bottle body to be filled
Bottleneck length be L2, then L1≤L2。
As a further improvement of the above technical scheme: the diameter of the aeration aperture is no more than the one of the needle tubing diameter
Half.
A kind of packaging process, comprising the following steps:
S1, filling preceding inflation: inert gas is filled in bottle body；
S2, filling: filling needle enters liquid drug in bottle body；
S3, filling rear inflation: inert gas is filled in bottle body using filling Aerating needle above-mentioned；
S4, the sealing of bottle body melt drawing.
Compared with the prior art, the advantages of the present invention are as follows: filling Aerating needle disclosed by the invention, aeration aperture is diagonally downward
Arrangement can guarantee to spray from the aeration aperture arranged diagonally downward, without going out after inert gas enters needle tubing from top to bottom
Existing negative inspiratory pressure phenomenon, while the air-flow diagonally downward sprayed from aeration aperture cooperates gravity, is conducive to bottle body inner wall
Remaining medical fluid is blown off downwards, and the medical fluid for remaining in bottleneck inner wall when high-temperature fusion drawing seal is avoided to generate chemical change,
The substance that black will not be generated, which covers, guarantees the drug quality after encapsulating on surface；Axial direction between aeration aperture along needle tubing has
Spacing, so as to process the aeration aperture in enough apertures, it is ensured that aeration aperture sprays enough air-flows, guarantees blowing off for residual liquor
Effect.
Packaging process disclosed by the invention is just filled with inert gas before filling, reduces the intracorporal air content of bottle, special
It is not oxygen and the gas that may be dissolved in liquid drug, advantageously ensures that quality and the shelf-life of filling drug；After filling
It is inflated again using above-mentioned filling Aerating needle, deoxygenation while can blow off the remaining medical fluid of bottle body inner wall, avoid high temperature melting
The medical fluid for remaining in bottleneck inner wall when melting drawing seal generates chemical change, and the substance that will not generate black covers on surface,
Drug quality after guaranteeing encapsulation.
Detailed description of the invention
Fig. 1 is the schematic view of the front view of the filling Aerating needle of the present invention.
Fig. 2 is the overlooking structure diagram of the filling Aerating needle of the present invention.
Fig. 3 is the partial enlarged view in Fig. 1.
Structural schematic diagram when Fig. 4 is inflation before packaging process of the present invention is filling.
Fig. 5 is structural schematic diagram when packaging process of the present invention is filling.
Fig. 6 is that filling Aerating needle of the invention enters the structural schematic diagram before bottle body.
Fig. 7 be filling Aerating needle of the invention enter bottle body carry out it is filling after inflation when structural schematic diagram.
Structural schematic diagram when Fig. 8 is packaging process melt drawing of the present invention sealing.
Fig. 9 is the structural schematic diagram after packaging process melt drawing sealing of the present invention.
Each label indicates in figure: 1, needle tubing；11, aeration aperture；2, aeration gas flow；3, bottle body；4, residual liquor；5, filling
Needle.
Specific embodiment
Below in conjunction with Figure of description and specific embodiment, invention is further described in detail.
Fig. 1 to Fig. 3 and Fig. 7 shows a kind of embodiment of the filling Aerating needle of the present invention, the filling inflation of the present embodiment
Needle, including needle tubing 1 offer multiple aeration apertures 11 on the tube wall of needle tubing 1, and aeration aperture 11 is arranged diagonally downward, along the axis of needle tubing 1
To with spacing between at least two aeration apertures 11.
The filling Aerating needle, aeration aperture 11 arrange diagonally downward, can after inert gas enters needle tubing 1 from top to bottom
Guarantee to spray from the aeration aperture 11 arranged diagonally downward, without negative inspiratory pressure phenomenon, while being sprayed from aeration aperture 11
Air-flow diagonally downward cooperates gravity, is conducive to downwards blow off the residual liquor 4 of 3 inner wall of bottle body, avoids high-temperature fusion
The medical fluid for remaining in bottleneck inner wall when drawing seal generates chemical change, and the substance that will not generate black covers on surface, protects
Drug quality after card encapsulation；There is spacing along the axial direction of needle tubing 1 between aeration aperture 11, so as to process filling for enough apertures
Stomata 11, it is ensured that aeration aperture 11 sprays enough air-flows, and guarantee residual liquor 4 blows off effect.
As a preferred technical solution, in the present embodiment, there are three aeration aperture 11 is set, along the axis projection of needle tubing 1, three
Aeration aperture 11 is evenly arranged in 120 ° of angles, can guarantee that 3 bottleneck inner wall of bottle body can circumferentially be inflated the ejection of hole 11 in this way
Air-flow blow to.
The angle between the axis of the axis and needle tubing 1 of aeration aperture 11 is β as a preferred technical solution, then 20 °≤β
≤70°.Angle β in the range, on the one hand advantageously ensures that the effect of blowing off of residual liquor 4, is on the other hand also convenient for inflating
The machining in hole 11 reduces manufacturing cost.In the present embodiment, β=30 °, so that the air-flow that aeration aperture 11 sprays has enough
Intensity, residual liquor 4, which is blown off, to work well.It certainly in other embodiments can also appropriate adjustment within the above range.
As a preferred technical solution, in the present embodiment, needle tubing 1 is 1 lower ending opening of hollow structure namely needle tubing, rather than
Enclosed construction.Current rate in needle tubing 1, needle can effectively be weakened by the aeration aperture 11 arranged diagonally downward in this present embodiment
Even if 1 lower end of pipe is open, the current rate of ejection will not be excessive, not will lead to medical fluid and splashes；Further, needle tubing 1 uses
Lower ending opening structure, is conducive to improve the speed of gas discharge in bottle body 3, and then improves filling efficiency.Certainly in other implementations
In example, enclosed construction in the prior art is can also be used in 1 lower end of needle tubing, and the speed that only gas is discharged in bottle body 3 is slower.
The axial spacing between aeration aperture 11 is L as a preferred technical solution,1, the bottleneck length of bottle body 3 to be filled is
L2, then L1≤L2, each aeration aperture 11 can be made to be respectively positioned in bottleneck length range in this way.
The diameter of aeration aperture 11 is no more than the half of 1 diameter of needle tubing as a preferred technical solution, can either guarantee to remain
Medical fluid blows off effect, and advantageously ensures that the mechanical strength of needle tubing 1.
Fig. 4 to Fig. 9 shows a kind of embodiment of packaging process of the present invention, the packaging process of the present embodiment, including following
Step:
S1, filling preceding inflation: inert gas is filled in bottle body 3；
S2, filling: filling needle 5 enters liquid drug in bottle body 3；
S3, filling rear inflation: inert gas is filled in bottle body 3 using above-mentioned filling Aerating needle；
S4, the sealing of 3 melt drawing of bottle body.
The packaging process is just filled with inert gas in bottle body 3 before filling, it is possible to reduce the air in bottle body 3 contains
Amount, especially oxygen and the gas that may be dissolved in liquid drug, advantageously ensure that quality and the shelf-life of filling drug；It is filling
It is inflated again using above-mentioned filling Aerating needle later, deoxygenation while can blow off the residual liquor 4 of 3 inner wall of bottle body, avoid
The medical fluid for remaining in bottleneck inner wall when high-temperature fusion drawing seal generates chemical change, and the substance that will not generate black covers
Surface, the drug quality after guaranteeing encapsulation.
Wherein, conventional, only lower ending opening Aerating needle can be used in step S1 to be inflated；It can be used in step S2 often
The filling needle 5 of rule carries out filling.
Although the present invention has been disclosed as a preferred embodiment, however, it is not intended to limit the invention.It is any to be familiar with ability
The technical staff in domain, without deviating from the scope of the technical scheme of the present invention, all using the technology contents pair of the disclosure above
Technical solution of the present invention makes many possible changes and modifications or equivalent example modified to equivalent change.Therefore, all
Without departing from the content of technical solution of the present invention, according to the present invention technical spirit any simple modification made to the above embodiment,
Equivalent variations and modification, all shall fall within the protection scope of the technical scheme of the invention.
Claims (8)
1. a kind of filling Aerating needle, including needle tubing (1), offered multiple aeration apertures (11) on the tube wall of the needle tubing (1), it is special
Sign is: the aeration aperture (11) is arranged diagonally downward, the axial direction along the needle tubing (1), at least two aeration apertures (11)
Between have spacing.
2. filling Aerating needle according to claim 1, it is characterised in that: there are three the aeration aperture (11) sets, along described
The axis projection of needle tubing (1), three aeration apertures (11) are evenly arranged in 120 ° of angles.
3. filling Aerating needle according to claim 1 or 2, it is characterised in that: the axis of the aeration aperture (11) with it is described
Angle between the axis of needle tubing (1) is β, then 20 °≤β≤70 °.
4. filling Aerating needle according to claim 3, it is characterised in that: β=30 °.
5. filling Aerating needle according to claim 1 or 2, it is characterised in that: the needle tubing (1) is hollow structure.
6. filling Aerating needle according to claim 1 or 2, it is characterised in that: between the axial direction between the aeration aperture (11)
Away from for L1, the bottleneck length of bottle body (3) to be filled is L2, then L1≤L2。
7. filling Aerating needle according to claim 1 or 2, it is characterised in that: the diameter of the aeration aperture (11) is no more than
The half of needle tubing (1) diameter.
8. a kind of packaging process, it is characterised in that: the following steps are included:
S1, filling preceding inflation: inert gas is filled in bottle body (3)；
S2, filling: filling needle (5) enters bottle body (3) interior liquid drug；
S3, filling rear inflation: inertia is filled in bottle body (3) using filling Aerating needle described in any one of any one of claims 1 to 77
Gas；
S4, the sealing of bottle body (3) melt drawing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910023515.6A CN109704258B (en) | 2019-01-10 | 2019-01-10 | Filling air needle and filling method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910023515.6A CN109704258B (en) | 2019-01-10 | 2019-01-10 | Filling air needle and filling method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN109704258A true CN109704258A (en) | 2019-05-03 |
| CN109704258B CN109704258B (en) | 2024-05-14 |
Family
ID=66260014
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910023515.6A Active CN109704258B (en) | 2019-01-10 | 2019-01-10 | Filling air needle and filling method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109704258B (en) |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4840014A (en) * | 1985-11-28 | 1989-06-20 | The Coca-Cola Company | Process for producing bottled beverages |
| CN201660423U (en) * | 2010-02-09 | 2010-12-01 | 芜湖康奇制药有限公司 | Needle tube for small-volume injection filling and sealing machine |
| CN201912451U (en) * | 2011-01-07 | 2011-08-03 | 张兰英 | Powder needle for preparing liquid medicine |
| CN102317163A (en) * | 2009-04-08 | 2012-01-11 | 日清奥利友集团株式会社 | Method and device for producing liquid food packed in container |
| DE102013107573A1 (en) * | 2013-07-16 | 2015-01-22 | Khs Gmbh | Filling element and filling machine with such a filling element |
| CN205419749U (en) * | 2016-03-14 | 2016-08-03 | 江西傲新生物科技有限公司 | Ampoule wire drawing filling and sealing machine |
| CN206064449U (en) * | 2016-09-18 | 2017-04-05 | 北京亿昊基因技术有限公司 | A kind of biological test vessel for preventing liquid splash |
| CN107539937A (en) * | 2016-06-28 | 2018-01-05 | 张银华 | A kind of three syringe needle group formula liquid filling and sealing machines |
| CN209367786U (en) * | 2019-01-10 | 2019-09-10 | 楚天科技股份有限公司 | A kind of filling Aerating needle |
-
2019
- 2019-01-10 CN CN201910023515.6A patent/CN109704258B/en active Active
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4840014A (en) * | 1985-11-28 | 1989-06-20 | The Coca-Cola Company | Process for producing bottled beverages |
| CN102317163A (en) * | 2009-04-08 | 2012-01-11 | 日清奥利友集团株式会社 | Method and device for producing liquid food packed in container |
| CN201660423U (en) * | 2010-02-09 | 2010-12-01 | 芜湖康奇制药有限公司 | Needle tube for small-volume injection filling and sealing machine |
| CN201912451U (en) * | 2011-01-07 | 2011-08-03 | 张兰英 | Powder needle for preparing liquid medicine |
| DE102013107573A1 (en) * | 2013-07-16 | 2015-01-22 | Khs Gmbh | Filling element and filling machine with such a filling element |
| CN205419749U (en) * | 2016-03-14 | 2016-08-03 | 江西傲新生物科技有限公司 | Ampoule wire drawing filling and sealing machine |
| CN107539937A (en) * | 2016-06-28 | 2018-01-05 | 张银华 | A kind of three syringe needle group formula liquid filling and sealing machines |
| CN206064449U (en) * | 2016-09-18 | 2017-04-05 | 北京亿昊基因技术有限公司 | A kind of biological test vessel for preventing liquid splash |
| CN209367786U (en) * | 2019-01-10 | 2019-09-10 | 楚天科技股份有限公司 | A kind of filling Aerating needle |
Also Published As
| Publication number | Publication date |
|---|---|
| CN109704258B (en) | 2024-05-14 |
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