CN109651026A - A kind of new use for explosive type stimulation medicament and preparation method thereof - Google Patents
A kind of new use for explosive type stimulation medicament and preparation method thereof Download PDFInfo
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- CN109651026A CN109651026A CN201811627596.2A CN201811627596A CN109651026A CN 109651026 A CN109651026 A CN 109651026A CN 201811627596 A CN201811627596 A CN 201811627596A CN 109651026 A CN109651026 A CN 109651026A
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- C—CHEMISTRY; METALLURGY
- C06—EXPLOSIVES; MATCHES
- C06B—EXPLOSIVES OR THERMIC COMPOSITIONS; MANUFACTURE THEREOF; USE OF SINGLE SUBSTANCES AS EXPLOSIVES
- C06B23/00—Compositions characterised by non-explosive or non-thermic constituents
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Abstract
The invention discloses a kind of new use for explosive type stimulation medicaments and preparation method thereof, belong to explosion medicament technical field, including following ingredient: high-purity capsaicine, compounding diatomite, guaiacol sodium, iron hydroxide, nanometer calper calcium peroxide, alcohol compound, azole compounds, lubrication bleeding agent, Hinered phenols antioxidant, surfactant, polyoxyethylene 20 sorbitan monolaurate, stabilization agent, alum, dispersing agent and water.By the present invention in that substitute original stimulant with high-purity capsaicine, which has the characteristics that environmental protection, efficient, using the original chemical synthesis stimulant of novel environment friendly stimulant substitution, by adjusting associated formula.
Description
Technical field
The present invention relates to a kind of stimulation medicament and preparation method thereof, more particularly to a kind of new use for explosive type stimulate medicament and
Preparation method belongs to explosion medicament technical field.
Background technique
Original stimulation medicament mainly uses o-chlorobenzylidene malononitrile, mainly by chemical synthesis, environmental pollution
Seriously, capsaicine 8- methy-N-vanillyl -6- nonenamide is the active constituent of capsicum, capsaicine and more relative
Compound and referred to as capsicum member, are the secondary metabolites that capsicum generates, and pure pepper element is a kind of hydrophobic lipophilic, colourless odorless
Crystallization or waxy compound.
Summary of the invention
The main object of the present invention is to provide for a kind of new use for explosive type stimulation medicament and preparation method thereof, by using
High-purity capsaicine substitutes original stimulant, makes it have environmental protection, efficient feature.
The purpose of the present invention can reach by using following technical solution:
A kind of new use for explosive type stimulation medicament, including following ingredient: high-purity capsaicine, compounding diatomite, guaiacol
Sodium, iron hydroxide, nanometer calper calcium peroxide, alcohol compound, azole compounds, lubrication bleeding agent, Hinered phenols antioxidant, surface
Activating agent, polyoxyethylene 20 sorbitan monolaurate, stabilization agent, alum, dispersing agent and water.
In percentage by weight, including following ingredient: 5~10 parts of high-purity capsaicine, 15~35 parts of diatomite of compounding,
5~10 parts of guaiacol sodium, 5~25 parts of 15~45 part, nanometer calper calcium peroxide of iron hydroxide, 0.5~2 part of alcohol compound, azoles
0.4~0.5 part of class compound, lubrication 2~3 parts of bleeding agent, 0.2~0.4 part of Hinered phenols antioxidant, surfactant 0.5~1
Part, 3~7 parts of polyoxyethylene 20 sorbitan monolaurate, 0.1~0.5 part of stabilization agent, 3~7 parts of alum, dispersing agent 1~5
Part, 15~35 parts of water.
In percentage by weight, including following ingredient: 8 parts of high-purity capsaicine, compounding 25 parts of diatomite, guaiacol
7 parts of sodium, 18 parts of 20 part, nanometer calper calcium peroxide of iron hydroxide, 1.5 parts of alcohol compound, 0.5 part of azole compounds, lubrication infiltration
2.5 parts of agent, 0.3 part of Hinered phenols antioxidant, 0.8 part of surfactant, 5 parts of polyoxyethylene 20 sorbitan monolaurate,
0.3 part of stabilization agent, 5 parts of alum, 3 parts of dispersing agent, 25 parts of water.
Nanometer calper calcium peroxide is 25~200nm of partial size powder, and the granular size for compounding diatomite is 100 mesh~5000 mesh,
Compounding diatomite is that FeCl3 compounds diatomite, Al2 (SO4) 3 compounds diatomite or PAM compounds diatomite.
Alcohol compound is any one or any a variety of mixture in methanol, ethyl alcohol, ethylene glycol and glycerine.
Azole compounds are any one in benzotriazole, methylbenzotriazole and mercapto benzothiazole.
Surfactant is anionic surfactant and nonionic surfactant；Anionic surfactant is 12
At least one of sodium alkyl benzene sulfonate, dodecyl trimethyl ammonium bromide, anionic surfactant by mass ratio be 10:(1~
3) neopelex and dodecyl trimethyl ammonium bromide compounding is made；Nonionic surfactant is poly- for alkyl phenol
Ethylene oxide ether, alkyl phenol polyoxyethylene ether include octyl phenol polyoxyethylene ether and nonylphenol polyoxyethylene ether.
Stabilization agent is oxalic acid or phosphoric acid；Lubrication bleeding agent is diethylene glycol monomethyl ether, polysorbate, phthalic anhydride and skin
Any one in resin acid or any a variety of mixture.
Dispersing agent is compounded by sodium carboxymethylcellulose, sodium metasilicate, Sodium Polyacrylate and is made, and mass ratio is 1:(2~4):
(0.3~0.8).
A kind of preparation method of new use for explosive type stimulation medicament, comprising the following steps:
Step 1: the salt acid soak of addition 20% in diatomite is compounded to 15~35 parts, 100 DEG C of heating water baths stir simultaneously
It mixes, adds water to keep stoste 2h, rinsed after cooling with water, filtered, 105 DEG C of drying are spare；
Step 2: the compounding diatomite dried in step 1 being put into ball mill, 5~10 parts of guaiacol sodium, 3 are added
~7 parts of alum and 5~10 parts of high-purity capsaicines, carry out 70~80min of dry grinding, obtain active mixture；
Step 3: under room temperature, water being put into reaction kettle, active mixture, 0.5~2 part of alcohols chemical combination are then sequentially added
Object and 0.2~0.4 part of Hinered phenols antioxidant add 0.1~0.5 part of stabilization agent and stir to dissolution the pH 7.0 for making solution
~8.0, it is stirred for simultaneously rising temperature for dissolving, 60 DEG C~65 DEG C heat preservation 1h is warming up to and obtains dissolved solution for later use；
Step 4: 15~45 parts of iron hydroxides and 3~7 parts of polyoxyethylene sorbitan lists are sequentially added into emulsion pot
Laurate is added 2~3 parts of lubrication bleeding agents after stirring 30~50min, stirs to being completely dissolved, be warming up to 80 DEG C, constant temperature is standby
With；
Step 5: 5~25 parts of nanometer calper calcium peroxides are added into reaction kettle again, 0.5~1 part of surface is added after stirring 60min
Activating agent, stirring and dissolving under the conditions of 70 DEG C~80 DEG C；
Step 6: 0.4~0.5 part of azole compounds is added into reaction kettle again, 1~5 part of dispersion is added after stirring 50min
Agent is stirred under the conditions of 70 DEG C~80 DEG C to being completely dissolved, and is then kept the temperature under the conditions of 70 DEG C~80 DEG C spare；
Step 7: starting emulsion pot stirring, revolving speed is adjusted to 60 turns/min, successively the production of step 3, step 4 and step 6
Object puts into emulsion pot and stirs 20min；
Step 8: the product of step 7 is pumped into homogenizer, homogeneous 3 times, each 3min；
Step 9: after the completion of homogeneous, inspection by sampling discharges filling after the assay was approved.
Advantageous effects of the invention: new use for explosive type stimulation medicament provided by the invention and preparation method thereof passes through
Original stimulant is substituted using high-purity capsaicine, which has the characteristics that environmentally friendly, efficient, uses novel environment friendly
Stimulant substitutes original chemical synthesis stimulant, by adjusting associated formula.
Specific embodiment
To make the more clear and clear technical solution of the present invention of those skilled in the art, below with reference to embodiment to this hair
Bright to be described in further detail, embodiments of the present invention are not limited thereto.
Embodiment 1:
The new use for explosive type that the present embodiment 1 provides stimulates medicament, in percentage by weight, including following ingredient: it is high-purity
Spend 5 parts of capsaicine, compounding 15 parts of diatomite, 5 parts of guaiacol sodium, 5 parts of 15 part, nanometer calper calcium peroxide of iron hydroxide, alcohols
Close 0.5 part of object, 0.4 part of azole compounds, lubrication 2 parts of bleeding agent, 0.2 part of Hinered phenols antioxidant, 0.5 part of surfactant,
3 parts of polyoxyethylene 20 sorbitan monolaurate, 0.1 part of stabilization agent, 3 parts of alum, 1 part of dispersing agent, 15 parts of water.
In the present embodiment 1, nanometer calper calcium peroxide is 25~200nm of partial size powder, and the granular size for compounding diatomite is
100 mesh~5000 mesh, compounding diatomite are that FeCl3 compounds diatomite, Al2 (SO4) 3 compounds diatomite or PAM compounds diatomite.
In the present embodiment 1, alcohol compound be in methanol, ethyl alcohol, ethylene glycol and glycerine any one or it is any
A variety of mixtures；Azole compounds are any one in benzotriazole, methylbenzotriazole and mercapto benzothiazole.
In the present embodiment 1, surfactant is anionic surfactant and nonionic surfactant；Anion table
Face activating agent be at least one of neopelex, dodecyl trimethyl ammonium bromide, anionic surfactant by
Mass ratio be 10:(1~3) neopelex and dodecyl trimethyl ammonium bromide compounding be made；Non-ionic surface
Activating agent is alkyl phenol polyoxyethylene ether, and alkyl phenol polyoxyethylene ether includes octyl phenol polyoxyethylene ether and Nonyl pheno
Ether.
In the present embodiment 1, stabilization agent is oxalic acid or phosphoric acid；Lubrication bleeding agent is diethylene glycol monomethyl ether, polysorbate, neighbour
Any one in phthalate anhydride and sebacic acid or any a variety of mixture；Dispersing agent is by sodium carboxymethylcellulose, silicic acid
Sodium, Sodium Polyacrylate compounding are made, and mass ratio is 1:(2~4): (0.3~0.8).
In the present embodiment 1, the preparation method for the new use for explosive type stimulation medicament that the present embodiment 1 provides, including following step
It is rapid:
Step 1: the salt acid soak of addition 20% in diatomite is compounded to 15 parts, 100 DEG C of heating water baths stir simultaneously, add
Water keeps stoste 2h, is rinsed after cooling with water, filters, 105 DEG C of drying, spare；
Step 2: the compounding diatomite dried in step 1 is put into ball mill, add 5 parts of guaiacol sodium, 3 parts it is bright
Alum and 5 parts of high-purity capsaicines, carry out 70~80min of dry grinding, obtain active mixture；
Step 3: under room temperature, water being put into reaction kettle, active mixture, 0.5 part of alcohol compound are then sequentially added
With 0.2 part of Hinered phenols antioxidant, adds 0.1 part of stabilization agent and stir to dissolution the pH 7.0~8.0 for making solution, be stirred for
And rising temperature for dissolving, it is warming up to 60 DEG C~65 DEG C heat preservation 1h and obtains dissolved solution for later use；
Step 4: 15 parts of iron hydroxides and 3 parts of polyoxyethylene sorbitan mono laurates are sequentially added into emulsion pot
Ester is added 2.5 parts of lubrication bleeding agents after stirring 30~50min, stirs to being completely dissolved, be warming up to 80 DEG C, constant temperature is spare；
Step 5: 5 parts of nanometer calper calcium peroxides are added into reaction kettle again, 0.5 part of surfactant is added after stirring 60min,
Stirring and dissolving under the conditions of 70 DEG C~80 DEG C；
Step 6: 0.4 part of azole compounds is added into reaction kettle again, 1 part of dispersing agent is added after stirring 50min, at 70 DEG C
It is stirred under the conditions of~80 DEG C to being completely dissolved, is then kept the temperature under the conditions of 70 DEG C~80 DEG C spare；
Step 7: starting emulsion pot stirring, revolving speed is adjusted to 60 turns/min, successively the production of step 3, step 4 and step 6
Object puts into emulsion pot and stirs 20min；
Step 8: the product of step 7 is pumped into homogenizer, homogeneous 3 times, each 3min；
Step 9: after the completion of homogeneous, inspection by sampling discharges filling after the assay was approved.
Embodiment 2:
The new use for explosive type that the present embodiment 2 provides stimulates medicament, in percentage by weight, including following ingredient: it is high-purity
Spend 8 parts of capsaicine, compounding 25 parts of diatomite, 7 parts of guaiacol sodium, 18 parts of 20 part, nanometer calper calcium peroxide of iron hydroxide, alcohols
Close 1.5 parts of object, 0.5 part of azole compounds, lubrication 2.5 parts of bleeding agent, 0.3 part of Hinered phenols antioxidant, surfactant 0.8
Part, 5 parts of polyoxyethylene 20 sorbitan monolaurate, 0.3 part of stabilization agent, 5 parts of alum, 3 parts of dispersing agent, 25 parts of water.
In the present embodiment 2, nanometer calper calcium peroxide is 25~200nm of partial size powder, and the granular size for compounding diatomite is
100 mesh~5000 mesh, compounding diatomite are that FeCl3 compounds diatomite, Al2 (SO4) 3 compounds diatomite or PAM compounds diatomite.
In the present embodiment 2, alcohol compound be in methanol, ethyl alcohol, ethylene glycol and glycerine any one or it is any
A variety of mixtures；Azole compounds are any one in benzotriazole, methylbenzotriazole and mercapto benzothiazole.
In the present embodiment 2, surfactant is anionic surfactant and nonionic surfactant；Anion table
Face activating agent be at least one of neopelex, dodecyl trimethyl ammonium bromide, anionic surfactant by
Mass ratio be 10:(1~3) neopelex and dodecyl trimethyl ammonium bromide compounding be made；Non-ionic surface
Activating agent is alkyl phenol polyoxyethylene ether, and alkyl phenol polyoxyethylene ether includes octyl phenol polyoxyethylene ether and Nonyl pheno
Ether.
In the present embodiment 2, stabilization agent is oxalic acid or phosphoric acid；Lubrication bleeding agent is diethylene glycol monomethyl ether, polysorbate, neighbour
Any one in phthalate anhydride and sebacic acid or any a variety of mixture；Dispersing agent is by sodium carboxymethylcellulose, silicic acid
Sodium, Sodium Polyacrylate compounding are made, and mass ratio is 1:(2~4): (0.3~0.8).
In the present embodiment 2, the preparation method for the new use for explosive type stimulation medicament that the present embodiment 2 provides, including following step
It is rapid:
Step 1: the salt acid soak of addition 20% in diatomite is compounded to 25 parts, 100 DEG C of heating water baths stir simultaneously, add
Water keeps stoste 2h, is rinsed after cooling with water, filters, 105 DEG C of drying, spare；
Step 2: the compounding diatomite dried in step 1 is put into ball mill, add 7 parts of guaiacol sodium, 5 parts it is bright
Alum and 8 parts of high-purity capsaicines, carry out 70~80min of dry grinding, obtain active mixture；
Step 3: under room temperature, water being put into reaction kettle, active mixture, 1.5 parts of alcohol compounds are then sequentially added
With 0.3 part of Hinered phenols antioxidant, adds 0.3 part of stabilization agent and stir to dissolution the pH 7.0~8.0 for making solution, be stirred for
And rising temperature for dissolving, it is warming up to 60 DEG C~65 DEG C heat preservation 1h and obtains dissolved solution for later use；
Step 4: 20 parts of iron hydroxides and 5 parts of polyoxyethylene sorbitan mono laurates are sequentially added into emulsion pot
Ester is added 2.5 parts of lubrication bleeding agents after stirring 30~50min, stirs to being completely dissolved, be warming up to 80 DEG C, constant temperature is spare；
Step 5: 18 parts of nanometer calper calcium peroxides are added into reaction kettle again, 0.8 part of surface-active is added after stirring 60min
Agent, stirring and dissolving under the conditions of 70 DEG C~80 DEG C；
Step 6: 0.5 part of azole compounds is added into reaction kettle again, 3 parts of dispersing agents are added after stirring 50min, at 70 DEG C
It is stirred under the conditions of~80 DEG C to being completely dissolved, is then kept the temperature under the conditions of 70 DEG C~80 DEG C spare；
Step 7: starting emulsion pot stirring, revolving speed is adjusted to 60 turns/min, successively the production of step 3, step 4 and step 6
Object puts into emulsion pot and stirs 20min；
Step 8: the product of step 7 is pumped into homogenizer, homogeneous 3 times, each 3min；
Step 9: after the completion of homogeneous, inspection by sampling discharges filling after the assay was approved.
Embodiment 3:
The new use for explosive type that the present embodiment 3 provides stimulates medicament, in percentage by weight, including following ingredient: it is high-purity
Spend 10 parts of capsaicine, compounding 35 parts of diatomite, 10 parts of guaiacol sodium, 25 parts of 45 part, nanometer calper calcium peroxide of iron hydroxide, alcohols
2 parts of compound, 3 parts of bleeding agent of lubrication, 0.4 part of Hinered phenols antioxidant, 1 part of surfactant, gathers 0.5 part of azole compounds
7 parts of ethylene oxide sorbitan mono-laurate, 0.5 part of stabilization agent, 7 parts of alum, 5 parts of dispersing agent, 35 parts of water.
In the present embodiment 3, nanometer calper calcium peroxide is 25~200nm of partial size powder, and the granular size for compounding diatomite is
100 mesh~5000 mesh, compounding diatomite are that FeCl3 compounds diatomite, Al2 (SO4) 3 compounds diatomite or PAM compounds diatomite.
In the present embodiment 3, alcohol compound be in methanol, ethyl alcohol, ethylene glycol and glycerine any one or it is any
A variety of mixtures；Azole compounds are any one in benzotriazole, methylbenzotriazole and mercapto benzothiazole.
In the present embodiment 3, surfactant is anionic surfactant and nonionic surfactant；Anion table
Face activating agent be at least one of neopelex, dodecyl trimethyl ammonium bromide, anionic surfactant by
Mass ratio be 10:(1~3) neopelex and dodecyl trimethyl ammonium bromide compounding be made；Non-ionic surface
Activating agent is alkyl phenol polyoxyethylene ether, and alkyl phenol polyoxyethylene ether includes octyl phenol polyoxyethylene ether and Nonyl pheno
Ether.
In the present embodiment 3, stabilization agent is oxalic acid or phosphoric acid；Lubrication bleeding agent is diethylene glycol monomethyl ether, polysorbate, neighbour
Any one in phthalate anhydride and sebacic acid or any a variety of mixture；Dispersing agent is by sodium carboxymethylcellulose, silicic acid
Sodium, Sodium Polyacrylate compounding are made, and mass ratio is 1:(2~4): (0.3~0.8).
In the present embodiment 3, the preparation method for the new use for explosive type stimulation medicament that the present embodiment 3 provides, including following step
It is rapid:
Step 1: the salt acid soak of addition 20% in diatomite is compounded to 35 parts, 100 DEG C of heating water baths stir simultaneously, add
Water keeps stoste 2h, is rinsed after cooling with water, filters, 105 DEG C of drying, spare；
Step 2: the compounding diatomite dried in step 1 being put into ball mill, 10 parts of guaiacol sodium, 7 parts are added
Alum and 10 parts of high-purity capsaicines, carry out 70~80min of dry grinding, obtain active mixture；
Step 3: under room temperature, will water put into reaction kettle in, then sequentially add active mixture, 2 parts of alcohol compounds and
0.4 part of Hinered phenols antioxidant adds 0.5 part of stabilization agent and stirs to dissolution the pH 7.0~8.0 for making solution, is stirred for simultaneously
Rising temperature for dissolving is warming up to 60 DEG C~65 DEG C heat preservation 1h and obtains dissolved solution for later use；
Step 4: 45 parts of iron hydroxides and 7 parts of polyoxyethylene sorbitan mono laurates are sequentially added into emulsion pot
Ester is added 3 parts of lubrication bleeding agents after stirring 30~50min, stirs to being completely dissolved, be warming up to 80 DEG C, constant temperature is spare；
Step 5: 25 parts of nanometer calper calcium peroxides are added into reaction kettle again, 1 part of surfactant is added after stirring 60min,
Stirring and dissolving under the conditions of 70 DEG C~80 DEG C；
Step 6: 0.5 part of azole compounds is added into reaction kettle again, 5 parts of dispersing agents are added after stirring 50min, at 70 DEG C
It is stirred under the conditions of~80 DEG C to being completely dissolved, is then kept the temperature under the conditions of 70 DEG C~80 DEG C spare；
Step 7: starting emulsion pot stirring, revolving speed is adjusted to 60 turns/min, successively the production of step 3, step 4 and step 6
Object puts into emulsion pot and stirs 20min；
Step 8: the product of step 7 is pumped into homogenizer, homogeneous 3 times, each 3min；
Step 9: after the completion of homogeneous, inspection by sampling discharges filling after the assay was approved.
In the above-described embodiments, new use for explosive type provided by the above embodiment stimulates medicament, by using high-purity capsicum
Element substitutes original stimulant, which has the characteristics that environmental protection, efficient, original using novel environment friendly stimulant substitution
Chemical synthesis stimulant, by adjusting associated formula.
The above, further embodiment only of the present invention, but scope of protection of the present invention is not limited thereto, and it is any
Within the scope of the present disclosure, according to the technique and scheme of the present invention and its design adds those familiar with the art
With equivalent substitution or change, protection scope of the present invention is belonged to.
Claims (10)
1. a kind of new use for explosive type stimulates medicament, which is characterized in that including following ingredient: high-purity capsaicine, compounding diatomite,
Guaiacol sodium, iron hydroxide, nanometer calper calcium peroxide, alcohol compound, azole compounds, lubrication bleeding agent, Hinered phenols are anti-
Oxygen agent, surfactant, polyoxyethylene 20 sorbitan monolaurate, stabilization agent, alum, dispersing agent and water.
2. a kind of new use for explosive type as described in claim 1 stimulates medicament, which is characterized in that in percentage by weight, packet
Include following ingredient: 5~10 parts of high-purity capsaicine, compounding 15~35 parts of diatomite, 5~10 parts of guaiacol sodium, iron hydroxide
15~45 5~25 parts of part, nanometer calper calcium peroxides, 0.5~2 part of alcohol compound, 0.4~0.5 part of azole compounds, lubrication infiltration
2~3 parts of agent, 0.2~0.4 part of Hinered phenols antioxidant, 0.5~1 part of surfactant, polyoxyethylene sorbitan list laurel
3~7 parts of acid esters, 0.1~0.5 part of stabilization agent, 3~7 parts of alum, 1~5 part of dispersing agent, 15~35 parts of water.
3. a kind of new use for explosive type as claimed in claim 2 stimulates medicament, which is characterized in that in percentage by weight, packet
Include following ingredient: 8 parts of high-purity capsaicine, compounding 25 parts of diatomite, 7 parts of guaiacol sodium, 20 part, nanometer peroxide of iron hydroxide
Change 18 parts of calcium, 1.5 parts of alcohol compound, 0.5 part of azole compounds, lubrication 2.5 parts of bleeding agent, 0.3 part of Hinered phenols antioxidant,
0.8 part of surfactant, 5 parts of polyoxyethylene 20 sorbitan monolaurate, 0.3 part of stabilization agent, 5 parts of alum, dispersing agent 3
Part, 25 parts of water.
4. a kind of new use for explosive type as claimed in claim 2 stimulates medicament, which is characterized in that nanometer calper calcium peroxide is partial size 25
~200nm powder, compound diatomite granular size be 100 mesh~5000 mesh, compounding diatomite be FeCl3 compound diatomite,
Al2 (SO4) 3 compounds diatomite or PAM compounds diatomite.
5. a kind of new use for explosive type as claimed in claim 2 stimulates medicament, which is characterized in that alcohol compound is methanol, second
Any one in alcohol, ethylene glycol and glycerine or any a variety of mixture.
6. a kind of new use for explosive type as claimed in claim 2 stimulates medicament, which is characterized in that azole compounds are parallel three nitrogen of benzene
Any one in azoles, methylbenzotriazole and mercapto benzothiazole.
7. a kind of new use for explosive type as claimed in claim 2 stimulates medicament, which is characterized in that surfactant is anion table
Face activating agent and nonionic surfactant；Anionic surfactant is neopelex, trimethyl
At least one of ammonium bromide, anionic surfactant by mass ratio be 10:(1~3) neopelex and 12
Alkyl trimethyl ammonium bromide compounding is made；Nonionic surfactant is alkyl phenol polyoxyethylene ether, alkyl phenol polyoxyethylene ether
Including octyl phenol polyoxyethylene ether and nonylphenol polyoxyethylene ether.
8. a kind of new use for explosive type as claimed in claim 2 stimulates medicament, which is characterized in that stabilization agent is oxalic acid or phosphoric acid；
Lubrication bleeding agent be in diethylene glycol monomethyl ether, polysorbate, phthalic anhydride and sebacic acid any one or it is any a variety of
Mixture.
9. a kind of new use for explosive type as claimed in claim 2 stimulates medicament, which is characterized in that dispersing agent is by carboxymethyl cellulose
Sodium, sodium metasilicate, Sodium Polyacrylate compounding are made, and mass ratio is 1:(2~4): (0.3~0.8).
10. a kind of preparation method of new use for explosive type stimulation medicament as described in any one of claims 1-9, feature exist
In, comprising the following steps:
Step 1: the salt acid soak of addition 20% in diatomite is compounded to 15~35 parts, 100 DEG C of heating water baths stir simultaneously, add
Water keeps stoste 2h, is rinsed after cooling with water, filters, 105 DEG C of drying, spare；
Step 2: the compounding diatomite dried in step 1 being put into ball mill, 5~10 parts of guaiacol sodium, 3~7 are added
Part alum and 5~10 parts of high-purity capsaicines, carry out 70~80min of dry grinding, obtain active mixture；
Step 3: under room temperature, will water put into reaction kettle in, then sequentially add active mixture, 0.5~2 part of alcohol compound and
0.2~0.4 part of Hinered phenols antioxidant, add 0.1~0.5 part of stabilization agent stir to dissolution make the pH 7.0 of solution~
8.0, it is stirred for simultaneously rising temperature for dissolving, 60 DEG C~65 DEG C heat preservation 1h is warming up to and obtains dissolved solution for later use；
Step 4: 15~45 parts of iron hydroxides and 3~7 parts of polyoxyethylene sorbitan list laurels are sequentially added into emulsion pot
Acid esters is added 2~3 parts of lubrication bleeding agents after stirring 30~50min, stirs to being completely dissolved, be warming up to 80 DEG C, constant temperature is spare；
Step 5: 5~25 parts of nanometer calper calcium peroxides are added into reaction kettle again, 0.5~1 part of surface-active is added after stirring 60min
Agent, stirring and dissolving under the conditions of 70 DEG C~80 DEG C；
Step 6: 0.4~0.5 part of azole compounds is added into reaction kettle again, 1~5 part of dispersing agent is added after stirring 50min,
It stirs under the conditions of 70 DEG C~80 DEG C to being completely dissolved, is then kept the temperature under the conditions of 70 DEG C~80 DEG C spare；
Step 7: starting emulsion pot stirring, revolving speed is adjusted to 60 turns/min, successively the product of step 3, step 4 and step 6 is thrown
Enter emulsion pot stirring 20min；
Step 8: the product of step 7 is pumped into homogenizer, homogeneous 3 times, each 3min；
Step 9: after the completion of homogeneous, inspection by sampling discharges filling after the assay was approved.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113135812A (en) * | 2021-05-20 | 2021-07-20 | 江西省李渡烟花集团有限公司 | Low-temperature safe and environment-friendly firework with carmine and yellow green light |
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