CN109498145A - A kind of cryoablation balloon system - Google Patents
A kind of cryoablation balloon system Download PDFInfo
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- CN109498145A CN109498145A CN201910009256.1A CN201910009256A CN109498145A CN 109498145 A CN109498145 A CN 109498145A CN 201910009256 A CN201910009256 A CN 201910009256A CN 109498145 A CN109498145 A CN 109498145A
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- sacculus
- tube
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- distal end
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00345—Vascular system
- A61B2018/00351—Heart
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00791—Temperature
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
- A61B2018/0212—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques using an instrument inserted into a body lumen, e.g. catheter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
- A61B2018/0231—Characteristics of handpieces or probes
- A61B2018/0262—Characteristics of handpieces or probes using a circulating cryogenic fluid
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- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
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- General Health & Medical Sciences (AREA)
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- Thermotherapy And Cooling Therapy Devices (AREA)
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Abstract
This application discloses a kind of cryoablation balloon systems, including sacculus assembly, tube assembly, Handleset, sacculus assembly includes outer sacculus and the interior sacculus that is arranged in outer sacculus, outer sacculus and interior sacculus are shrinkable and expansion utricule structure, tube assembly includes the outer tube being successively socketed from outside to inside, intermediate tube and inner tube, the proximal end of outer sacculus and the distal end of outer tube connect, the proximal end of interior sacculus and the distal end of intermediate tube connect, the distal end of outer sacculus and interior sacculus is then connect with the distal end of inner tube, between outer sacculus and interior sacculus, vacuum lumen is formed between outer tube and intermediate tube, several temperature measuring points are additionally provided at the vacuum lumen, between interior sacculus and inner tube, freezing inner cavity is formed between intermediate tube and inner tube.Distal end uses interior sacculus and outer balloon structure, and the vacuum lumen in surgical procedure internally between sacculus and outer sacculus is evacuated to it and fits closely, and temperature measuring point of the setting in vacuo at chamber can accurately measure the cryoablation temperature that outer sacculus is contacted with orifices of pulmonary veins.
Description
Technical field
The present invention relates to the field of medical instrument technology, more particularly to it is a kind of can accurate temperature adjustment cryoablation balloon system.
Background technique
Auricular fibrillation (atrial fibrillation) is the clinically most common pathologic arrhythmia cordis.The disease incidence of atrial fibrillation is whole in recent decades
Body is in rising trend, may be related with the increase of aging of population and incidence of cardiovascular disease, has studies have shown that expect 2050
Year U.S.'s patients with atrial fibrillation will increase to 5,600,000 by 2,300,000 in 2000.It is serious simultaneously that auricular fibrillation may cause cerebral apoplexy etc.
Disease is sent out, is brought about great losses to patient and society, how to treat atrial fibrillation as current research emphasis.The atrial fibrillation cause of disease is complicated, until
Modern not yet complete thoroughly research, it is believed that most of atrial fibrillations are by originating from pulmonary vein and atrium sinistrum intersection or pulmonary vein
What interior fast electric excitement was triggered, therefore it is that conduit disappears that pulmonary vein, which is electrically isolated (Pulmonary Vein Isolation, PVI),
Melt " foundation stone " for the treatment of atrial fibrillation.
Freezing foley's tube (Cryoballoon Catheter, CBA) is to have been used for the maturation the most of atrial fibrillation therapy at present
New catheter ablation techniques, which is reclined orifices of pulmonary veins by full sacculus, when liquid refrigerant (N2O) is in sacculus
When injection caburation, amount of heat is absorbed, so that target ablation spot temperature is reduced to irreversible damage, to realize pulmonary vein electricity
Isolation.But there is also shortcomings for existing product, comprising: on the one hand, since the temperature measuring point of current cryoablation conduit is general
The position for being all disposed within balloon lumen, rather than reclining with cardiac muscle, therefore it is unable to the actual cryoablation temperature of Accurate Determining；It is another
Aspect, during refrigerant is delivered in distal balloon catheter by injection-tube from the proximal end of cryoablation conduit, refrigerant energy
It can cause damages during transportation.The defect of product structure design described above leads to the measurement that system cannot be accurate and tune
Save actual cryoablation temperature.Temperature drift cannot realize that pulmonary vein is electrically isolated well, influence success rate of operation；Temperature
It is relatively low, freezing energy pulmonary vein perienchyma can be acted on, lead to related complication, as diaphragmatic paralysis, vagus nerve injury,
Esophagus fistula etc. carries out pulmonary vein electric isolution, diaphragm using Medtronic Arctic Front Advance product according to reports indicate that
Neural paralysis incidence is up to 13.5%.
Summary of the invention
The application technical problems to be solved be to provide it is a kind of can precise temperature control cryoablation balloon system.
In order to solve the above-mentioned technical problem, this application provides a kind of cryoablation balloon systems, including sacculus assembly, pipe
Component, Handleset, the sacculus assembly include outer sacculus and the interior sacculus that is arranged in outer sacculus, and outer sacculus and interior sacculus are
Shrinkable and expansion utricule structure, the tube assembly includes the outer tube, intermediate tube and inner tube being successively socketed from outside to inside, ectosphere
The proximal end of capsule and the distal end of outer tube connect, and the proximal end of interior sacculus and the distal end of intermediate tube connect, the distal end of outer sacculus and interior sacculus
It is then connect with the distal end of inner tube, between the outer sacculus and interior sacculus, forms vacuum lumen between outer tube and intermediate tube, it is described true
It is additionally provided with several temperature measuring points at empty inner cavity, forms freezing inner cavity between interior sacculus and inner tube, between intermediate tube and inner tube.
Preferably, the Handleset includes guidewire interface, gas interface and electric interfaces.
Preferably, temperature measuring point is set on the inner wall of outer sacculus, the diameter maximum of outer sacculus to the distal side of outer sacculus every
Between multiple annular temperature measuring point groups, the temperature measuring point structure that each annular temperature measuring point group is arranged by multiple circumferentially uniform intervals is distributed with
At.
Preferably, the temperature measuring point is thermoelectricity occasionally thermal resistance, and the thermoelectricity occasionally thermal resistance passes through vacuum lumen cloth
It sets and is electrically connected with electric interfaces.
Preferably, intracavitary in the freezing to be disposed with injection-tube, the distal end of the injection-tube is fixed on remote in interior sacculus
End side, the injection-tube distal end are equipped with several injection orifices.
Preferably, the Cryoablation system further includes recording unit, the temperature measured for recording each temperature measuring point in real time
Degree；Unit is adjusted, the temperature for measuring according to temperature measuring point adjusts the conveying of refrigerant in injection-tube.
Preferably, the cryoablation balloon system further includes several vacuum units and refrigerant supply unit, the gas
Body interface includes multiple cavities for being respectively communicated with several vacuum units and refrigerant supply unit, in the vacuum lumen, freezing
The cavity that chamber passes through respectively in gas interface is connect with vacuum unit, and the injection-tube passes through cavity and freezing in gas interface
The connection of agent supply unit gas.
Preferably, the guidewire interface connect with inner tube and can control the movement of inner tube axial reciprocating.
Preferably, the cryoablation foley's tube is built-in with several draught lines, and the distal anchor of the draught line is due to outer
The proximal end of the distal end of pipe, the draught line is connect with knob, and the movement of draught line is driven by Turning knob.
A kind of cryoablation balloon system of the application, has the advantages that
Distal end uses interior sacculus and outer balloon structure, in surgical procedure internally the vacuum lumen between sacculus and outer sacculus take out it is true
Sky is fitted closely to it, and the temperature measuring point at chamber in vacuo, which is arranged, can accurately measure the freezing that outer sacculus is contacted with orifices of pulmonary veins
Temperature is melted, the cryoablation temperature feedback measured to unit is adjusted, is adjusted unit and then pass through adjusting refrigerant by recording unit
Conveying realize precise temperature control.
Outer balloon diameter maximum is circumferentially arranged with several temperature measuring points to distal side, to guarantee that sacculus assembly is quiet with lung
Arteries and veins mouth can accurately measure actual cryoablation temperature in the case where difference reclines state.
Several vacuum units vacuumize vacuum lumen and freezing inner cavity, so that injection-tube is in refrigerant transmission process
In obtain dual insulated heat, on the one hand can reduce the thermal loss of injection-tube, what another aspect refrigerant more can be stable is defeated
It send to sacculus assembly, the conveying of refrigerant can accurately more be adjusted by adjusting unit, to realize precise temperature control.
Detailed description of the invention
Fig. 1 is cryoablation balloon catheter structure schematic diagram of the invention；
Fig. 2 is cryoablation foley's tube distal structure schematic diagram of the invention；
Fig. 3 is the corresponding right view of Fig. 2；
Fig. 4 is the schematic diagram of cryoablation foley's tube in use.
In the figures above: 1, sacculus assembly；2, tube assembly；3, Handleset；31, knob；32, push rod；33, seal wire connects
Mouthful；34, gas interface；35, electric interfaces；11, temperature measuring point；12, outer sacculus；13, interior sacculus；21, outer tube；22, intermediate tube；
23, inner tube；24, injection-tube；14, vacuum lumen；15, inner cavity is freezed；100, pulmonary vein；200, atrium sinistrum.
Specific embodiment
The application is described further in the following with reference to the drawings and specific embodiments, so that those skilled in the art can be with
It more fully understands the application and can be practiced, but illustrated embodiment is not as the restriction to the application.
As shown in Figures 1 to 4, it is a kind of can precise temperature control cryoablation balloon system, including cryoablation foley's tube,
Cryoablation foley's tube includes the sacculus assembly 1, tube assembly 2 and Handleset 3 being sequentially connected, and Handleset includes that seal wire connects
Mouth 33, gas interface 34 and electric interfaces 35, sacculus assembly 1 include outer interior sacculus sacculus 12 and be arranged in outer sacculus 12
13, outer sacculus 12 and interior sacculus 13 are utricule structure and shrinkable and expansion；Interior sacculus 13 is dimensioned slightly smaller than outer sacculus 12, examines
Consider the individual difference of patient, different size can be set into interior sacculus 13 and outer sacculus 12, and such as outer balloon diameter can be
23mm or 28mm, sacculus 13 selects PET/Pebax/PA/Tpu material in outer sacculus 12/.
Tube assembly 2 includes outer tube 21, intermediate tube 22 and the inner tube 23 being successively socketed, proximal end and the outer tube 21 of outer sacculus 12
Distal end connects, and the proximal end of interior sacculus 13 connect with the distal end of intermediate tube 22, the distal end of outer sacculus 12 and interior sacculus 13 then with inner tube
Thermal weld or bonding way can be used in 23 distal end connection, connection type.
Between outer sacculus 12 and interior sacculus 13, vacuum lumen 14 is formed between outer tube 21 and intermediate tube 22, in clinical use
In the process, by adjusting the vacuum degree of vacuum lumen 14 outer sacculus 12 and interior sacculus 13 are fitted closely, at vacuum lumen 14
Several temperature measuring points 11 are additionally provided with, form freezing inner cavity 15 between interior sacculus 13 and inner tube 23, between intermediate tube 21 and inner tube 23,
By injecting refrigerant/pumping in freezing inner cavity 15, the expansion/contraction of sacculus assembly 1 is realized.
Temperature measuring point 11 is arranged at the inner wall of outer sacculus 12, the diameter maximum of outer sacculus 12 to the distal side of outer sacculus 12
Multiple annular temperature measuring point groups, the temperature measuring point that each annular temperature measuring point group is arranged by multiple circumferentially uniform intervals is distributed in compartment
It constitutes, temperature measuring point 11 is thermocouple/thermal resistance, and thermocouple/thermal resistance is arranged by vacuum lumen and is electrically connected with electric interfaces 35
It connects.As shown in figure 4, temperature measuring point 11 using this kind of structure arrangement, guarantees that 100 mouthfuls of sacculus assembly and pulmonary vein recline state in difference
Under, it can accurately measure actual cryoablation temperature.
It there also is provided injection-tube 24 in freezing inner cavity 15, injection-tube 24 uses elastomeric NiTi material, injection-tube 24
Distal end is located at the distal side for the cavity that interior sacculus 13 is formed, and injection-tube 24 distal end is equipped with several injection orifices, in order to more evenly
Refrigerant is sent to sacculus 13 and is formed in volume cavity, the arrangement of injection orifice can use helical form, ring-type along the axial direction of inner tube 23
Deng design.The injection-tube 24 is by between the intermediate tube 22 and inner tube 23, the distal end of the injection-tube 24 is fixed
On the outside of the inner tube.
Cryoablation system further include: recording unit, recording unit can record the temperature that each temperature measuring point 11 measures in real time；
Unit is adjusted, the conveying of refrigerant in injection-tube 24 is adjusted according to the temperature measured, in one embodiment, unit is adjusted and uses
Valve class formation adjusts the conveying of refrigerant by controlling the flow of refrigerant.
Gas interface 34 includes multiple independent cavities, and cryoablation balloon system further includes several vacuum units and freezing
Agent supply unit, vacuum lumen 14/ freeze inner cavity 15 and are connect by gas interface 34 with vacuum unit gas, and injection-tube 24 passes through
Gas interface 34 is connect with refrigerant supply unit gas.
Guidewire interface 33 connect with inner tube 23 and is axially reciprocal movement, adjusts sacculus assembly by movable wire guide interface 33
1 shape.
Cryoablation foley's tube is also built-in with several draught lines, and the distal anchor of draught line schedules the distal end of outer tube 21, leads
The proximal end of lead is connect with knob 31, the movement of draught line is driven by Turning knob 31, to realize that cryoablation sacculus is led
Deflection/bending of pipe distal end.The draught line can be embedded in the outer tube wall, also can be by the outer tube in
Between between pipe.
It is as follows to the mechanism of cryoablation temperature progress fine adjustment in the present embodiment:
Refrigerant is sent to interior sacculus 13 by injection-tube, interior sacculus 13 and outer sacculus are in expanded state；
In refrigerant injection process, vacuum unit vacuumizes (such as Fig. 2 arrow institute vacuum lumen 14 and freezing inner cavity 15
Show) so that injection-tube 24 obtains dual insulated heat in refrigerant transmission process, the heat of injection-tube 24 on the one hand can be reduced
Amount loss, what another aspect refrigerant more can be stable is delivered in sacculus assembly 1；
Outer balloon diameter maximum and distal side are circumferentially arranged with several temperature measuring points, to guarantee that sacculus assembly is quiet with lung
100 mouthfuls of arteries and veins, in the case where difference reclines state, can accurately measure actual cryoablation temperature；
Temperature measuring point records the cryoablation temperature that outer sacculus is contacted with 100 mouthfuls of pulmonary vein, and will be warm by electric interfaces 35
Degree signal is sent to recording unit, and temperature signal is fed back to adjusting unit again by recording unit, is adjusted unit and is then passed through adjusting freezing
The feed flow of agent realizes precise temperature control.
Alleged proximal end refers to one end close to patient in the course of surgery in the present invention, distally refers in surgical procedure
One end far from patient.
Embodiment described above is only the preferred embodiment lifted to absolutely prove the application, the protection model of the application
It encloses without being limited thereto.Those skilled in the art made equivalent substitute or transformation on the basis of the application, in the application
Protection scope within.The protection scope of the application is subject to claims.
Claims (9)
1. a kind of cryoablation balloon system, including sacculus assembly, tube assembly, Handleset, which is characterized in that
The sacculus assembly includes outer sacculus and the interior sacculus that is arranged in outer sacculus, and outer sacculus and interior sacculus are shrinkable and expand
The utricule structure opened,
The tube assembly includes the outer tube, intermediate tube and inner tube being successively socketed from outside to inside, the proximal end of outer sacculus and outer tube it is remote
End connection, the proximal end of interior sacculus and the distal end of intermediate tube connect, and the distal end of outer sacculus and interior sacculus is then connect with the distal end of inner tube,
Vacuum lumen is formed between the outer sacculus and interior sacculus, between outer tube and intermediate tube, is also set up at the vacuum lumen
There are several temperature measuring points, forms freezing inner cavity between interior sacculus and inner tube, between intermediate tube and inner tube.
2. a kind of cryoablation balloon system as described in claim 1, which is characterized in that the Handleset includes that seal wire connects
Mouth, gas interface and electric interfaces.
3. a kind of cryoablation balloon system as claimed in claim 2, which is characterized in that temperature measuring point is set to the inner wall of outer sacculus
On, multiple annular temperature measuring point groups, each annular thermometric is distributed in the distal side compartment of diameter maximum to the outer sacculus of outer sacculus
Point group is made of the temperature measuring point that multiple circumferentially uniform intervals are arranged.
4. a kind of cryoablation balloon system as claimed in claim 3, which is characterized in that the temperature measuring point is that thermoelectricity is occasionally warm
Resistance, the thermoelectricity occasionally thermal resistance are arranged by vacuum lumen and are electrically connected with electric interfaces.
5. a kind of cryoablation balloon system as claimed in claim 2, which is characterized in that intracavitary in the freezing to be disposed with note
Pipe is penetrated, the distal side in interior sacculus is fixed in the distal end of the injection-tube, and the injection-tube distal end is equipped with several injection orifices.
6. a kind of cryoablation balloon system as described in claim 1, which is characterized in that the Cryoablation system also wraps
It includes,
Recording unit, the temperature measured for recording each temperature measuring point in real time；
Unit is adjusted, the temperature for measuring according to temperature measuring point adjusts the conveying of refrigerant in injection-tube.
7. a kind of cryoablation balloon system as claimed in claim 5, which is characterized in that the cryoablation balloon system is also
Including several vacuum units and refrigerant supply unit, the gas interface includes multiple several vacuum units and cold of being respectively communicated with
Freeze the cavity of agent supply unit, the vacuum lumen, freezing inner cavity pass through cavity and vacuum unit company in gas interface respectively
It connects, the injection-tube is connect by the cavity in gas interface with refrigerant supply unit gas.
8. a kind of cryoablation balloon system as claimed in claim 2, which is characterized in that the guidewire interface is connect with inner tube
And it is mobile to control inner tube axial reciprocating.
9. a kind of cryoablation balloon system as described in claim 1, which is characterized in that in the cryoablation foley's tube
Several draught lines are equipped with, the distal anchor of the draught line schedules the distal end of outer tube, and the proximal end of the draught line is connect with knob, leads to
Cross the movement that Turning knob drives draught line.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910009256.1A CN109498145B (en) | 2019-01-04 | 2019-01-04 | Cryoablation balloon system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910009256.1A CN109498145B (en) | 2019-01-04 | 2019-01-04 | Cryoablation balloon system |
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| CN109498145A true CN109498145A (en) | 2019-03-22 |
| CN109498145B CN109498145B (en) | 2023-07-18 |
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| CN201910009256.1A Active CN109498145B (en) | 2019-01-04 | 2019-01-04 | Cryoablation balloon system |
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Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110269674A (en) * | 2019-06-27 | 2019-09-24 | 深圳北芯生命科技有限公司 | Automatic Cryoablation system |
| CN110575243A (en) * | 2019-09-30 | 2019-12-17 | 科塞尔医疗科技（苏州）有限公司 | Balloon catheter and cryoablation instrument |
| CN111329575A (en) * | 2020-03-04 | 2020-06-26 | 上海微创电生理医疗科技股份有限公司 | Freezing sacculus pipe system |
| CN112294420A (en) * | 2019-08-02 | 2021-02-02 | 深圳北芯生命科技有限公司 | Cryoablation device with sensor array |
| WO2021027682A1 (en) * | 2019-08-14 | 2021-02-18 | 心诺普医疗技术（北京）有限公司 | Temperature-controllable cryoablation system |
| CN113425402A (en) * | 2021-08-27 | 2021-09-24 | 上海安钛克医疗科技有限公司 | Catheter capable of judging balloon adhesion and ablation system |
| CN113760003A (en) * | 2021-09-07 | 2021-12-07 | 苏州海宇新辰医疗科技有限公司 | Temperature control method, device and storage medium |
| CN113796945A (en) * | 2021-10-29 | 2021-12-17 | 苏州海宇新辰医疗科技有限公司 | Cryoablation tube |
| CN113827336A (en) * | 2021-10-26 | 2021-12-24 | 苏州海宇新辰医疗科技有限公司 | Freezing sacculus pipe |
| CN113842205A (en) * | 2021-11-11 | 2021-12-28 | 上海导向医疗系统有限公司 | Cryoablation needle with position-adjustable J-T groove |
| CN113876413A (en) * | 2021-11-17 | 2022-01-04 | 苏州海宇新辰医疗科技有限公司 | Injection tube for freezing sacculus and freezing sacculus catheter system |
| CN113925594A (en) * | 2021-10-15 | 2022-01-14 | 杭州心创医疗器械有限公司 | Balloon catheter |
| CN116898558A (en) * | 2023-06-26 | 2023-10-20 | 苏州海宇新辰医疗科技有限公司 | Balloon catheter for cardiac cryoablation |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110269674B (en) * | 2019-06-27 | 2024-05-28 | 深圳北芯生命科技股份有限公司 | Automatic cryoablation system |
| CN110269674A (en) * | 2019-06-27 | 2019-09-24 | 深圳北芯生命科技有限公司 | Automatic Cryoablation system |
| CN112294420A (en) * | 2019-08-02 | 2021-02-02 | 深圳北芯生命科技有限公司 | Cryoablation device with sensor array |
| WO2021027682A1 (en) * | 2019-08-14 | 2021-02-18 | 心诺普医疗技术（北京）有限公司 | Temperature-controllable cryoablation system |
| CN110575243A (en) * | 2019-09-30 | 2019-12-17 | 科塞尔医疗科技（苏州）有限公司 | Balloon catheter and cryoablation instrument |
| CN111329575A (en) * | 2020-03-04 | 2020-06-26 | 上海微创电生理医疗科技股份有限公司 | Freezing sacculus pipe system |
| CN113425402A (en) * | 2021-08-27 | 2021-09-24 | 上海安钛克医疗科技有限公司 | Catheter capable of judging balloon adhesion and ablation system |
| CN113760003A (en) * | 2021-09-07 | 2021-12-07 | 苏州海宇新辰医疗科技有限公司 | Temperature control method, device and storage medium |
| CN113760003B (en) * | 2021-09-07 | 2022-03-29 | 苏州海宇新辰医疗科技有限公司 | Temperature control method, device and storage medium |
| CN113925594A (en) * | 2021-10-15 | 2022-01-14 | 杭州心创医疗器械有限公司 | Balloon catheter |
| CN113925594B (en) * | 2021-10-15 | 2024-04-19 | 杭州心创医疗器械有限公司 | Balloon catheter |
| CN113827336B (en) * | 2021-10-26 | 2023-09-01 | 苏州海宇新辰医疗科技有限公司 | Freezing sacculus pipe |
| CN113827336A (en) * | 2021-10-26 | 2021-12-24 | 苏州海宇新辰医疗科技有限公司 | Freezing sacculus pipe |
| CN113796945B (en) * | 2021-10-29 | 2023-08-18 | 苏州海宇新辰医疗科技有限公司 | Cryoablation tube |
| CN113796945A (en) * | 2021-10-29 | 2021-12-17 | 苏州海宇新辰医疗科技有限公司 | Cryoablation tube |
| CN113842205A (en) * | 2021-11-11 | 2021-12-28 | 上海导向医疗系统有限公司 | Cryoablation needle with position-adjustable J-T groove |
| CN113876413A (en) * | 2021-11-17 | 2022-01-04 | 苏州海宇新辰医疗科技有限公司 | Injection tube for freezing sacculus and freezing sacculus catheter system |
| CN113876413B (en) * | 2021-11-17 | 2023-08-08 | 苏州海宇新辰医疗科技有限公司 | Injection tube for freezing saccule and freezing saccule catheter system |
| CN116898558A (en) * | 2023-06-26 | 2023-10-20 | 苏州海宇新辰医疗科技有限公司 | Balloon catheter for cardiac cryoablation |
| CN116898558B (en) * | 2023-06-26 | 2024-04-30 | 苏州海宇新辰医疗科技有限公司 | Balloon catheter for cardiac cryoablation |
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| CN109498145B (en) | 2023-07-18 |
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