CN109464337A - Compact anti-wrinkle essence - Google Patents
Compact anti-wrinkle essence Download PDFInfo
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- CN109464337A CN109464337A CN201811576757.XA CN201811576757A CN109464337A CN 109464337 A CN109464337 A CN 109464337A CN 201811576757 A CN201811576757 A CN 201811576757A CN 109464337 A CN109464337 A CN 109464337A
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- wrinkle
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
- A61K8/492—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid having condensed rings, e.g. indol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/645—Proteins of vegetable origin; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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Abstract
The invention discloses a kind of compact anti-wrinkle essence, count by weight percentage, formula mainly includes following components: goosefoot (CHENOPODIUM QUINOA) seed extract 0.5-5%, dipeptides diaminobutyryl benzyl amide diacetin 0.1-1%, hydroxyethyl piperazine ethane sulfonic acid 0.1-2%.Each component is arranged in pairs or groups according to special ratios, and the multiple efficacies ingredient being rich in, which reconciles mutually, to be cooperateed with and play maximum effect, effectively penetrates into skin skin corium, promote cell turnover and collagen synthesis, wrinkle reduction significantly improves the elasticity of skin, has the effect of compact skin.
Description
Technical field
The present invention relates to cosmetic fields, are specifically related to a kind of compact anti-wrinkle essence.
Background technique
Wrinkle is the initial sign of skin aging.After 25 years old, the ageing process of skin starts, and wrinkle occurs gradually.Out
Existing sequence is usually forehead, upper palpebra inferior, paropia, ear proparea, cheek, neck, lower chin, mouth week.With the age increase and
The infringement of external environment, the decline of Skin Cell activity, rate of metabolism slow down, and skin starts obvious aging, thinning of skin, change
Firmly, dry, tension reduces.Corium elastic fibrosis, fracture reduce the tension of skin and elasticity, after expression muscular relaxation,
Skin cannot restore quickly, and long mimetic muscle is not shunk, and wrinkle starts to deepen.Increase with the age, skin and subcutaneous tissue are more
Relaxation, in addition the atrophy of facial supporting tissue or missing and muscle is soft, skin will be slided under gravity
Pendant, forms deeper wrinkle.
In recent years, with the economic development and improvement of living standard of society, people preserve youthful looks to anti-aging, beauty, forever
The youth is preserved increasingly to pay attention to.But due to modern's work, the accelerating rhythm of life, some showed out shortly past 30 years old
The appearance and posture of beginning aging, as lusterless complexion, dark and gloomy raw spot, wrinkle it is wan and sallow.Anti-wrinkle product currently on the market continues to bring out,
Advertisement sentence sentence is tempting, but effect allows people to sigh with feeling.Many cosmetology skin care products largely can only be by skin surface institute
It absorbs, skin corium can not be actually entered and achieve the purpose that profound update and collagen is supplemented, cannot played
The effect of the compact skin of wrinkle.
Summary of the invention
The purpose of the present invention is to provide a kind of compact anti-wrinkle essence, have good compact anti-wrinkle effect.
The object of the invention is achieved through the following technical solutions:
A kind of compact anti-wrinkle essence mainly includes count by weight percentage following components: goosefoot (CHENOPODIUM
QUINOA) seed extract 0.5-5%, dipeptides diaminobutyryl benzyl amide diacetin 0.1-1%, hydroxyethyl piperazine ethane sulfonic acid
0.1-2%。
Further, the compact anti-wrinkle essence mainly includes count by weight percentage following components: Kun Nuoa
Chenopodiaceae (CHENOPODIUM QUINOA) seed extract 2.5%, dipeptides diaminobutyryl benzyl amide diacetin 0.5%, ethoxy
Piperazine ethanesulfonic acid 1%.
Further, the compact anti-wrinkle essence also includes count by weight percentage following components: acetyl group six
The 1 ‰ aqueous solution 0.1-2% of peptide -8, Bacillus acidi lactici/soya-bean milk tunning filtrate 0.1-1%, hydrolytic soya bean protein 0.1-1%, I
Primary gum (ACACIA SENEGAL) glue 0.1-1%.
In wherein some embodiments, the compact anti-wrinkle essence, count by weight percentage, also comprising with the following group
Point: 1 ‰ aqueous solution 1% of Argireline, Bacillus acidi lactici/soya-bean milk tunning filtrate 0.5%, hydrolytic soya bean protein 0.5%, Ah
Draw primary gum (ACACIA SENEGAL) glue 0.5%.
Further, the compact anti-wrinkle essence also includes the ispol of 1.1-5.5wt%.
Further, the ispol is aspartic acid, arginine, serine, alanine, glutamic acid, dried meat
The mixing of propylhomoserin, glycine, lysine, histidine, tryptophan, cystine.
Further, each component accounts for compact anti-wrinkle essence total weight percent in the ispol are as follows: asparagus fern
Propylhomoserin 0.1-0.5%, arginine 0.1-0.5%, serine 0.1-0.5%, alanine 0.1-0.5%, glutamic acid 0.1-0.5%, dried meat ammonia
Sour 0.1-0.5%, glycine 0.1-0.5%, lysine 0.1-0.5%, histidine 0.1-0.5%, tryptophan 0.1-0.5%, cystine
0.1-0.5%。
Further, the compact anti-wrinkle essence, consists of the following components in percentage by weight: carbomer 0.1-
0.3%, xanthan gum 0.05-0.15%, polyacrylate cross-linked polymer -6 0.01-0.1%, EDETATE SODIUM 0.01-0.05%, urine
Bursin 0.1-0.3%, methyl propanediol 1-5%, PEG/PPG-17/6 copolymer 0.1-2%, parahydroxyacet-ophenone 0.1-0.5%, thoroughly
Bright matter acid sodium 0.01-0.1%, glycerol caprylate 0.1-0.3%, decoyl hydroximic acid 0.1-0.3%, 1,2- hexylene glycol 0.1-1%, smart ammonia
Sour 0.1-0.3%, aspartic acid 0.1-0.5%, arginine 0.1-0.5%, serine 0.1-0.5%, alanine 0.1-0.5%, paddy ammonia
Sour 0.1-0.5%, proline 0.1-0.5%, glycine 0.1-0.5%, lysine 0.1-0.5%, histidine 0.1-0.5%, tryptophan
0.1-0.5%, cystine 0.1-0.5%, hydrolytic collagen 0.1-0.5%, goosefoot (CHENOPODIUM QUINOA) seed extract
0.5-5%, dipeptides diaminobutyryl benzyl amide diacetin 0.1-1%, hydroxyethyl piperazine ethane sulfonic acid 0.1-2%, acetyl group six
The 1 ‰ aqueous solution 0.1-2% of peptide -8, Bacillus acidi lactici/soya-bean milk tunning filtrate 0.1-1%, hydrolytic soya bean protein 0.1-1%, I
Primary gum (ACACIA SENEGAL) glue 0.1-1%, water surplus.
The present invention has the advantage that and the utility model has the advantages that
1, compact anti-wrinkle essence of the invention contains goosefoot (CHENOPODIUM QUINOA) seed extract, dipeptides diamino
Butyryl benzyl amide diacetin, hydroxyethyl piperazine ethane sulfonic acid, three's compounding share, and mildness is good, and penetration is superior, can have
Effect penetrates into skin skin corium, improves cell activity, promotes cell turnover and collagen synthesis, significantly improves the elasticity of skin,
Have effects that compact skin, wrinkle reduction, and compact anti-wrinkle persistent is effective.
2, compact anti-wrinkle essence of the invention can also add 1 ‰ aqueous solution of Argireline, Bacillus acidi lactici/soya-bean milk
Tunning filtrate, hydrolytic soya bean protein, acacia (ACACIA SENEGAL) glue, can further promote compact anti-wrinkle
Essence wrinkle reduction, the effect for improving skin elasticity.
Specific embodiment
With reference to embodiment to of the invention for a more detailed description, but embodiments of the present invention are not limited to
This can refer to routine techniques progress for not specifically specified technological parameter or condition.
Part material according to the present invention is described as follows:
Goosefoot (CHENOPODIUM QUINOA) seed extract of the present invention is that chenopod goosefoot seed extracts
It arrives.Suitably " goosefoot (CHENOPODIUM QUINOA) seed extract " can be from U.S. TRI-K
The NaturePep of Industries, Inc company®Quinoa product.Goosefoot seed rich in a variety of amino acid and flavonoids,
The multiple beneficials compound such as B family vitamin and E family vitamin, folic acid, linoleic acid, alpha-linolenic acid, beta glucan, can be thin for skin
Born of the same parents provide nutrient, effectively improve cell activity, promote cell turnover and collagen synthesis.
INCI title/the English name of " Bacillus acidi lactici/soya-bean milk tunning filtrate " of the present invention:
LACTOBACILLUS/SOYMILK FERMENT FILTRATE, suitable Bacillus acidi lactici/soya-bean milk tunning filtrate can be
From French Axialys trade name " VEYATECH®It is difficult to understand graceful quick " raw material.It is using soya-bean milk as fermentation substrate, using 35 kinds
Lactobacillus fermentation and the extract obtained have and relax rich in multivitamin and protein and Bacillus acidi lactici active constituent
It is slow, moisturizing, repairing effect.
Acacia (ACACIA SENEGAL) glue of the present invention, is derived from the juice of pulse family sallee Acacia
Liquid condenses.Suitable acacia (ACACIA SENEGAL) glue can be " Arabic gum gum powder " (from Thailand
Pacify city Kai Tong trade Co., Ltd), it is also possible to " gum arabic " (from Zhengzhou Kai Ying Chemical Co., Ltd.).Mainly at
Dividing has D- galactolipin, L-arabinose, D-Glucose aldehydic acid, L- rhamnose, 4-O- methyl-O- glucuronic acid etc..It is Arabic
Gum (ACACIA SENEGAL) glue is a kind of water-soluble natural glue, and in the industry, it is natural thickener, suspending agent, bonding
Agent, film forming agent；Medically gum arabic also has the function of reducing Blood Cholesterol.
Test 1 permeability test
Goosefoot (CHENOPODIUM QUINOA) seed extract, dipeptides diaminobutyryl benzyl amide two have been investigated in this experiment
Acetate, hydroxyethyl piperazine ethane sulfonic acid compound permeance property.Reference literature (Chen Lianghong nano-emulsion containing shea butter
The technology of preparing of liquid and its application study [D] Shanghai Institute Of Technology, 2015.) method that 5.2.7 ~ 5.2.8 section is recorded
Carry out following test:
Test specimen therein is prepared according to the following formulation:
Sample A, consists of the following components in percentage by weight: goosefoot (CHENOPODIUM QUINOA) seed extract
0.5%, dipeptides diaminobutyryl benzyl amide diacetin 1%, hydroxyethyl piperazine ethane sulfonic acid 0.1%, water surplus.
Sample B, consists of the following components in percentage by weight: goosefoot (CHENOPODIUM QUINOA) seed extract
5%, dipeptides diaminobutyryl benzyl amide diacetin 0.1%, hydroxyethyl piperazine ethane sulfonic acid 2%, water surplus.
Sample C, consists of the following components in percentage by weight: goosefoot (CHENOPODIUM QUINOA) seed extract
2.5%, dipeptides diaminobutyryl benzyl amide diacetin 0.5%, hydroxyethyl piperazine ethane sulfonic acid 1%, water surplus.
Sample a, consists of the following components in percentage by weight: goosefoot (CHENOPODIUM QUINOA) seed extract
4%, water surplus.
Sample b, consists of the following components in percentage by weight: dipeptides diaminobutyryl benzyl amide diacetin it is water-soluble
Liquid 4%, water surplus.
Sample c, consists of the following components in percentage by weight: the aqueous solution 4% of hydroxyethyl piperazine ethane sulfonic acid, more than water
Amount.
Experimental result is as shown in table 1.(note: in view of the service life of cosmetics is 2 times a day that every minor tick about 12 is small
When, therefore the accumulation infiltration capacity of 12 hours has been investigated in experiment).
1 permeability test result record sheet of table
By upper table 1 it is found that the permeability of sample A, B, C are better than sample a, b, c, it can be seen that, it is used in compounding goosefoot
(CHENOPODIUM QUINOA) seed extract, dipeptides diaminobutyryl benzyl amide diacetin, hydroxyethyl piperazine ethane sulphur
Sour three kinds of raw materials are than being used alone the permeability of wherein some raw material more preferably.
Embodiment 1
A kind of compact anti-wrinkle essence, consists of the following components in percentage by weight: carbomer 0.3%, xanthan gum 0.05%, polypropylene
Acid esters cross-linked polymer -6 0.1%, EDETATE SODIUM 0.01%, allantoin 0.3%, methyl propanediol 1%, PEG/PPG-17/6 copolymerization
Object 2%, parahydroxyacet-ophenone 0.1%, Sodium Hyaluronate 0.1%, glycerol caprylate 0.1%, decoyl hydroximic acid 0.3%, 1,2- hexylene glycol
0.1%, arginine 0.3%, aspartic acid 0.1%, arginine 0.5%, serine 0.1%, alanine 0.5%, glutamic acid 0.1%, dried meat ammonia
Acid 0.5%, glycine 0.1%, lysine 0.5%, histidine 0.1%, tryptophan 0.5%, cystine 0.1%, hydrolytic collagen 0.5%, elder brother
Promise Ah Chenopodiaceae (CHENOPODIUM QUINOA) seed extract 0.5%, dipeptides diaminobutyryl benzyl amide diacetin 1%, hydroxyl second
Base piperazine ethanesulfonic acid 0.1%, water surplus.
Embodiment 2
A kind of compact anti-wrinkle essence, consists of the following components in percentage by weight: carbomer 0.1%, xanthan gum 0.15%, polypropylene
Acid esters cross-linked polymer -6 0.01%, EDETATE SODIUM 0.05%, allantoin 0.1%, methyl propanediol 5%, PEG/PPG-17/6 is total
Polymers 0.1%, parahydroxyacet-ophenone 0.5%, Sodium Hyaluronate 0.01%, glycerol caprylate 0.3%, decoyl hydroximic acid 0.1%, 1,2-
Hexylene glycol 1%, arginine 0.1%, aspartic acid 0.5%, arginine 0.1%, serine 0.5%, alanine 0.1%, glutamic acid 0.5%,
Proline 0.1%, glycine 0.5%, lysine 0.1%, histidine 0.5%, tryptophan 0.1%, cystine 0.5%, hydrolytic collagen
0.1%, goosefoot (CHENOPODIUM QUINOA) seed extract 5%, dipeptides diaminobutyryl benzyl amide diacetin
0.1%, hydroxyethyl piperazine ethane sulfonic acid 2%, water surplus.
Embodiment 3
A kind of compact anti-wrinkle essence, consists of the following components in percentage by weight: carbomer 0.2%, xanthan gum 0.1%, polypropylene
Acid esters cross-linked polymer -6 0.05%, EDETATE SODIUM 0.03%, allantoin 0.2%, methyl propanediol 3%, PEG/PPG-17/6 is total
Polymers 1%, parahydroxyacet-ophenone 0.3%, Sodium Hyaluronate 0.05%, glycerol caprylate 0.2%, decoyl hydroximic acid 0.2%, 1,2- oneself
Glycol 0.5%, arginine 0.2%, aspartic acid 0.3%, arginine 0.3%, serine 0.3%, alanine 0.3%, glutamic acid 0.3%,
Proline 0.3%, glycine 0.3%, lysine 0.3%, histidine 0.3%, tryptophan 0.3%, cystine 0.3%, hydrolytic collagen
0.3%, goosefoot (CHENOPODIUM QUINOA) seed extract 2.5%, dipeptides diaminobutyryl benzyl amide diacetin
0.5%, hydroxyethyl piperazine ethane sulfonic acid 1%, water surplus.
Embodiment 4
A kind of compact anti-wrinkle essence, consists of the following components in percentage by weight: carbomer 0.2%, xanthan gum 0.1%, polypropylene
Acid esters cross-linked polymer -6 0.05%, EDETATE SODIUM 0.03%, allantoin 0.2%, methyl propanediol 3%, PEG/PPG-17/6 is total
Polymers 1%, parahydroxyacet-ophenone 0.3%, Sodium Hyaluronate 0.05%, glycerol caprylate 0.2%, decoyl hydroximic acid 0.2%, 1,2- oneself
Glycol 0.5%, arginine 0.2%, aspartic acid 0.3%, arginine 0.3%, serine 0.3%, alanine 0.3%, glutamic acid 0.3%,
Proline 0.3%, glycine 0.3%, lysine 0.3%, histidine 0.3%, tryptophan 0.3%, cystine 0.3%, hydrolytic collagen
0.3%, goosefoot (CHENOPODIUM QUINOA) seed extract 2.5%, dipeptides diaminobutyryl benzyl amide diacetin
0.5%, hydroxyethyl piperazine ethane sulfonic acid 1%, 1 ‰ aqueous solution 0.1% of Argireline, Bacillus acidi lactici/soya-bean milk tunning filter
Liquid 1%, hydrolytic soya bean protein 0.1%, acacia (ACACIA SENEGAL) glue 1%, water surplus.
Embodiment 5
A kind of compact anti-wrinkle essence, consists of the following components in percentage by weight: carbomer 0.2%, xanthan gum 0.1%, polypropylene
Acid esters cross-linked polymer -6 0.05%, EDETATE SODIUM 0.03%, allantoin 0.2%, methyl propanediol 3%, PEG/PPG-17/6 is total
Polymers 1%, parahydroxyacet-ophenone 0.3%, Sodium Hyaluronate 0.05%, glycerol caprylate 0.2%, decoyl hydroximic acid 0.2%, 1,2- oneself
Glycol 0.5%, arginine 0.2%, aspartic acid 0.3%, arginine 0.3%, serine 0.3%, alanine 0.3%, glutamic acid 0.3%,
Proline 0.3%, glycine 0.3%, lysine 0.3%, histidine 0.3%, tryptophan 0.3%, cystine 0.3%, hydrolytic collagen
0.3%, goosefoot (CHENOPODIUM QUINOA) seed extract 2.5%, dipeptides diaminobutyryl benzyl amide diacetin
0.5%, hydroxyethyl piperazine ethane sulfonic acid 1%, 1 ‰ aqueous solution 2% of Argireline, Bacillus acidi lactici/soya-bean milk tunning filtrate
0.1%, hydrolytic soya bean protein 1%, acacia (ACACIA SENEGAL) glue 0.1%, water surplus.
Embodiment 6
A kind of compact anti-wrinkle essence, consists of the following components in percentage by weight: carbomer 0.2%, xanthan gum 0.1%, polypropylene
Acid esters cross-linked polymer -6 0.05%, EDETATE SODIUM 0.03%, allantoin 0.2%, methyl propanediol 3%, PEG/PPG-17/6 is total
Polymers 1%, parahydroxyacet-ophenone 0.3%, Sodium Hyaluronate 0.05%, glycerol caprylate 0.2%, decoyl hydroximic acid 0.2%, 1,2- oneself
Glycol 0.5%, arginine 0.2%, aspartic acid 0.3%, arginine 0.3%, serine 0.3%, alanine 0.3%, glutamic acid 0.3%,
Proline 0.3%, glycine 0.3%, lysine 0.3%, histidine 0.3%, tryptophan 0.3%, cystine 0.3%, hydrolytic collagen
0.3%, goosefoot (CHENOPODIUM QUINOA) seed extract 2.5%, dipeptides diaminobutyryl benzyl amide diacetin
0.5%, hydroxyethyl piperazine ethane sulfonic acid 1%, 1 ‰ aqueous solution 1% of Argireline, Bacillus acidi lactici/soya-bean milk tunning filtrate
0.5%, hydrolytic soya bean protein 0.5%, acacia (ACACIA SENEGAL) glue 0.5%, water surplus.
Comparative example 1
A kind of compact anti-wrinkle essence, consists of the following components in percentage by weight: carbomer 0.2%, xanthan gum 0.1%, polypropylene
Acid esters cross-linked polymer -6 0.05%, EDETATE SODIUM 0.03%, allantoin 0.2%, methyl propanediol 3%, PEG/PPG-17/6 is total
Polymers 1%, parahydroxyacet-ophenone 0.3%, Sodium Hyaluronate 0.05%, glycerol caprylate 0.2%, decoyl hydroximic acid 0.2%, 1,2- oneself
Glycol 0.5%, arginine 0.2%, aspartic acid 0.3%, arginine 0.3%, serine 0.3%, alanine 0.3%, glutamic acid 0.3%,
Proline 0.3%, glycine 0.3%, lysine 0.3%, histidine 0.3%, tryptophan 0.3%, cystine 0.3%, hydrolytic collagen
0.3%, goosefoot (CHENOPODIUM QUINOA) seed extract 2.5%, water surplus.
Comparative example 2
A kind of compact anti-wrinkle essence, consists of the following components in percentage by weight: carbomer 0.2%, xanthan gum 0.1%, polypropylene
Acid esters cross-linked polymer -6 0.05%, EDETATE SODIUM 0.03%, allantoin 0.2%, methyl propanediol 3%, PEG/PPG-17/6 is total
Polymers 1%, parahydroxyacet-ophenone 0.3%, Sodium Hyaluronate 0.05%, glycerol caprylate 0.2%, decoyl hydroximic acid 0.2%, 1,2- oneself
Glycol 0.5%, arginine 0.2%, aspartic acid 0.3%, arginine 0.3%, serine 0.3%, alanine 0.3%, glutamic acid 0.3%,
Proline 0.3%, glycine 0.3%, lysine 0.3%, histidine 0.3%, tryptophan 0.3%, cystine 0.3%, hydrolytic collagen
0.3%, hydroxyethyl piperazine ethane sulfonic acid 1%, water surplus.
Comparative example 3
A kind of compact anti-wrinkle essence, consists of the following components in percentage by weight: carbomer 0.2%, xanthan gum 0.1%, polypropylene
Acid esters cross-linked polymer -6 0.05%, EDETATE SODIUM 0.03%, allantoin 0.2%, methyl propanediol 3%, PEG/PPG-17/6 is total
Polymers 1%, parahydroxyacet-ophenone 0.3%, Sodium Hyaluronate 0.05%, glycerol caprylate 0.2%, decoyl hydroximic acid 0.2%, 1,2- oneself
Glycol 0.5%, arginine 0.2%, aspartic acid 0.3%, arginine 0.3%, serine 0.3%, alanine 0.3%, glutamic acid 0.3%,
Proline 0.3%, glycine 0.3%, lysine 0.3%, histidine 0.3%, tryptophan 0.3%, cystine 0.3%, hydrolytic collagen
0.3%, dipeptides diaminobutyryl benzyl amide diacetin 0.5%, water surplus.
Comparative example 4
A kind of compact anti-wrinkle essence, consists of the following components in percentage by weight: carbomer 0.2%, xanthan gum 0.1%, polypropylene
Acid esters cross-linked polymer -6 0.05%, EDETATE SODIUM 0.03%, allantoin 0.2%, methyl propanediol 3%, PEG/PPG-17/6 is total
Polymers 1%, parahydroxyacet-ophenone 0.3%, Sodium Hyaluronate 0.05%, glycerol caprylate 0.2%, decoyl hydroximic acid 0.2%, 1,2- oneself
Glycol 0.5%, arginine 0.2%, aspartic acid 0.3%, arginine 0.3%, serine 0.3%, alanine 0.3%, glutamic acid 0.3%,
Proline 0.3%, glycine 0.3%, lysine 0.3%, histidine 0.3%, tryptophan 0.3%, cystine 0.3%, hydrolytic collagen
0.3%, goosefoot (CHENOPODIUM QUINOA) seed extract 2.5%, dipeptides diaminobutyryl benzyl amide diacetin
0.5%, hydroxyethyl piperazine ethane sulfonic acid 1%, 1 ‰ aqueous solution 1% of Argireline, water surplus.
Comparative example 5
A kind of compact anti-wrinkle essence, consists of the following components in percentage by weight: carbomer 0.2%, xanthan gum 0.1%, polypropylene
Acid esters cross-linked polymer -6 0.05%, EDETATE SODIUM 0.03%, allantoin 0.2%, methyl propanediol 3%, PEG/PPG-17/6 is total
Polymers 1%, parahydroxyacet-ophenone 0.3%, Sodium Hyaluronate 0.05%, glycerol caprylate 0.2%, decoyl hydroximic acid 0.2%, 1,2- oneself
Glycol 0.5%, arginine 0.2%, aspartic acid 0.3%, arginine 0.3%, serine 0.3%, alanine 0.3%, glutamic acid 0.3%,
Proline 0.3%, glycine 0.3%, lysine 0.3%, histidine 0.3%, tryptophan 0.3%, cystine 0.3%, hydrolytic collagen
0.3%, goosefoot (CHENOPODIUM QUINOA) seed extract 2.5%, dipeptides diaminobutyryl benzyl amide diacetin
0.5%, hydroxyethyl piperazine ethane sulfonic acid 1%, Bacillus acidi lactici/soya-bean milk tunning filtrate 0.5%, water surplus.
Comparative example 6
A kind of compact anti-wrinkle essence, consists of the following components in percentage by weight: carbomer 0.2%, xanthan gum 0.1%, polypropylene
Acid esters cross-linked polymer -6 0.05%, EDETATE SODIUM 0.03%, allantoin 0.2%, methyl propanediol 3%, PEG/PPG-17/6 is total
Polymers 1%, parahydroxyacet-ophenone 0.3%, Sodium Hyaluronate 0.05%, glycerol caprylate 0.2%, decoyl hydroximic acid 0.2%, 1,2- oneself
Glycol 0.5%, arginine 0.2%, aspartic acid 0.3%, arginine 0.3%, serine 0.3%, alanine 0.3%, glutamic acid 0.3%,
Proline 0.3%, glycine 0.3%, lysine 0.3%, histidine 0.3%, tryptophan 0.3%, cystine 0.3%, hydrolytic collagen
0.3%, goosefoot (CHENOPODIUM QUINOA) seed extract 2.5%, dipeptides diaminobutyryl benzyl amide diacetin
0.5%, hydroxyethyl piperazine ethane sulfonic acid 1%, hydrolytic soya bean protein 0.5%, water surplus.
Comparative example 7
A kind of compact anti-wrinkle essence, consists of the following components in percentage by weight: carbomer 0.2%, xanthan gum 0.1%, polypropylene
Acid esters cross-linked polymer -6 0.05%, EDETATE SODIUM 0.03%, allantoin 0.2%, methyl propanediol 3%, PEG/PPG-17/6 is total
Polymers 1%, parahydroxyacet-ophenone 0.3%, Sodium Hyaluronate 0.05%, glycerol caprylate 0.2%, decoyl hydroximic acid 0.2%, 1,2- oneself
Glycol 0.5%, arginine 0.2%, aspartic acid 0.3%, arginine 0.3%, serine 0.3%, alanine 0.3%, glutamic acid 0.3%,
Proline 0.3%, glycine 0.3%, lysine 0.3%, histidine 0.3%, tryptophan 0.3%, cystine 0.3%, hydrolytic collagen
0.3%, goosefoot (CHENOPODIUM QUINOA) seed extract 2.5%, dipeptides diaminobutyryl benzyl amide diacetin
0.5%, hydroxyethyl piperazine ethane sulfonic acid 1%, acacia (ACACIA SENEGAL) glue 0.5%, water surplus.
Blank control group
A kind of compact anti-wrinkle essence, consists of the following components in percentage by weight: carbomer 0.2%, xanthan gum 0.1%, polypropylene
Acid esters cross-linked polymer -6 0.05%, EDETATE SODIUM 0.03%, allantoin 0.2%, methyl propanediol 3%, PEG/PPG-17/6 is total
Polymers 1%, parahydroxyacet-ophenone 0.3%, Sodium Hyaluronate 0.05%, glycerol caprylate 0.2%, decoyl hydroximic acid 0.2%, 1,2- oneself
Glycol 0.5%, arginine 0.2%, aspartic acid 0.3%, arginine 0.3%, serine 0.3%, alanine 0.3%, glutamic acid 0.3%,
Proline 0.3%, glycine 0.3%, lysine 0.3%, histidine 0.3%, tryptophan 0.3%, cystine 0.3%, hydrolytic collagen
0.3%, water surplus.
In order to better illustrate the present invention the advantages of, below to compact anti-wrinkle essence product provided in an embodiment of the present invention into
Row efficacy test.
Test the test of 2 skin elasticities and anti-wrinkle test
By compact anti-wrinkle essence made from blank control group, embodiment 1-6 and comparative example 1-7 be used for wrinkles on one's forehead, river word line,
Crow's feet, decree line and neck line, and face has that skin is loose, volunteer of wrinkle problem tests.Every group is selected 20 respectively
Female volunteers of the age at 35~55 years old, volunteer use 2 times daily, apply after early, late face cleaning at face skin wrinkle position
Given the test agent is smeared, each usage amount is 0.01g/cm2, it is used continuously 3 months.It is surveyed by skinanalysis apparatus (MC750, German CK)
Determine skin of face elasticity, test result is as shown in table 2.After test, volunteer is paid a return visit, asks volunteer according to self
Skin anti-wrinkle effect is given a mark (from 0 to 10 point), and statistics marking obtains final appraisal result as a result, then average,
Being considered as higher than 6 points has anti-wrinkle effect, and being considered as lower than 6 points does not have anti-wrinkle effect, and concrete outcome is shown in Table 3.
2 skin elasticity test result table of table
Note: skin elasticity coefficients R2Numerical value it is bigger, skin elasticity is better.
By upper table 2 it is found that volunteer using embodiment 1-6 prepared by the present invention compact anti-wrinkle essence after, skin elasticity
Coefficient significantly improves, and shows that compact anti-wrinkle essence of the invention can be improved skin elasticity, increases the compact degree of skin.
And it is compared by embodiment 1-3 and comparative example 1-3 it is found that goosefoot (CHENOPODIUM QUINOA) seed extracts
Better effect when object, dipeptides diaminobutyryl benzyl amide diacetin, hydroxyethyl piperazine ethane sulfonic acid three share.
It is compared by embodiment 4-6 and comparative example 4-7, embodiment 1-3 it is found that 1 ‰ aqueous solution of Argireline, lactic acid
Bacillus/soya-bean milk tunning filtrate, hydrolytic soya bean protein, acacia (ACACIA SENEGAL) the glued used time can be further
Skin elasticity is promoted, when being applied alone, it is unobvious to promote effect.3 volunteer of table scoring record sheet
By self appraisal result of volunteer in upper table 3 it is found that the compact anti-wrinkle essence of embodiment 1-6 preparation all has anti-wrinkle effect
Fruit, hence it is evident that better than comparative example 1-3 (scoring is all lower than 6 points, and it is invalid to be considered as).Statistics uses as a result, analysis is found, prepared by the present invention
Compact anti-wrinkle essence of dispelling with good anti-wrinkle effect, skin smooth can be made fine and smooth, hence it is evident that reduce wrinkle.
Inquiry feedback is carried out to volunteer to learn, it is mild stingless using the compact anti-wrinkle essence of 1-6 of the embodiment of the present invention
Swash, has no adverse reaction, skin sense is good.
Embodiment described above only describe the preferred embodiments of the invention, not to model of the invention
It encloses and is defined, without departing from the spirit of the design of the present invention, those of ordinary skill in the art are to technical side of the invention
The various changes and improvements that case is made should all be fallen into the protection scope that claims of the present invention determines.
Claims (8)
1. a kind of compact anti-wrinkle essence, which is characterized in that count by weight percentage, formula mainly includes following components: elder brother's promise
Ah Chenopodiaceae (CHENOPODIUM QUINOA) seed extract 0.5-5%, dipeptides diaminobutyryl benzyl amide diacetin 0.1-1%,
Hydroxyethyl piperazine ethane sulfonic acid 0.1-2%.
2. compact anti-wrinkle essence according to claim 1, which is characterized in that count by weight percentage, be formulated main packet
Containing following components: goosefoot (CHENOPODIUM QUINOA) seed extract 2.5%, dipeptides diaminobutyryl benzyl amide two
Acetate 0.5%, hydroxyethyl piperazine ethane sulfonic acid 1%.
3. compact anti-wrinkle essence according to claim 1 or 2, which is characterized in that count by weight percentage, formula also wraps
Containing following components: 1 ‰ aqueous solution 0.1-2% of Argireline, Bacillus acidi lactici/soya-bean milk tunning filtrate 0.1-1%, hydrolysis
Soybean protein 0.1-1%, acacia (ACACIA SENEGAL) glue 0.1-1%.
4. compact anti-wrinkle essence according to claim 3, which is characterized in that also the amino acid comprising 1.1-5.5wt% mixes
Object.
5. compact anti-wrinkle essence according to claim 4, which is characterized in that the ispol is asparagus fern ammonia
Acid, arginine, serine, alanine, glutamic acid, proline, glycine, lysine, histidine, tryptophan, cystine it is mixed
It closes.
6. compact anti-wrinkle essence according to claim 5, which is characterized in that the ispol, each component account for
Compact anti-wrinkle essence total weight percent are as follows: aspartic acid 0.1-0.5%, arginine 0.1-0.5%, serine 0.1-0.5%, third
Propylhomoserin 0.1-0.5%, glutamic acid 0.1-0.5%, proline 0.1-0.5%, glycine 0.1-0.5%, lysine 0.1-0.5% organize ammonia
Sour 0.1-0.5%, tryptophan 0.1-0.5%, cystine 0.1-0.5%.
7. compact anti-wrinkle essence according to claim 3, which is characterized in that count by weight percentage, also comprising following
Component: 1 ‰ aqueous solution 1% of Argireline, Bacillus acidi lactici/soya-bean milk tunning filtrate 0.5%, hydrolytic soya bean protein 0.5%,
Acacia (ACACIA SENEGAL) glue 0.5%.
8. compact anti-wrinkle essence according to claim 1-7, which is characterized in that by the group of following weight percent
It is grouped as: carbomer 0.1-0.3%, xanthan gum 0.05-0.15%, polyacrylate cross-linked polymer -6 0.01-0.1%, EDTA
Disodium 0.01-0.05%, allantoin 0.1-0.3%, methyl propanediol 1-5%, PEG/PPG-17/6 copolymer 0.1-2%, to hydroxyl
Acetophenone 0.1-0.5%, Sodium Hyaluronate 0.01-0.1%, glycerol caprylate 0.1-0.3%, decoyl hydroximic acid 0.1-0.3%, 1,2-
Hexylene glycol 0.1-1%, arginine 0.1-0.3%, aspartic acid 0.1-0.5%, arginine 0.1-0.5%, serine 0.1-0.5%, third
Propylhomoserin 0.1-0.5%, glutamic acid 0.1-0.5%, proline 0.1-0.5%, glycine 0.1-0.5%, lysine 0.1-0.5% organize ammonia
Sour 0.1-0.5%, tryptophan 0.1-0.5%, cystine 0.1-0.5%, hydrolytic collagen 0.1-0.5%, goosefoot
(CHENOPODIUM QUINOA) seed extract 0.5-5%, dipeptides diaminobutyryl benzyl amide diacetin 0.1-1%, hydroxyl second
Base piperazine ethanesulfonic acid 0.1-2%, 1 ‰ aqueous solution 0.1-2% of Argireline, Bacillus acidi lactici/soya-bean milk tunning filtrate
0.1-1%, hydrolytic soya bean protein 0.1-1%, acacia (ACACIA SENEGAL) glue 0.1-1%, water surplus.
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| CN110115699A (en) * | 2019-04-16 | 2019-08-13 | 上海悦目化妆品有限公司 | A kind of eye essence and preparation method thereof |
| CN110613662A (en) * | 2019-10-22 | 2019-12-27 | 广东密尚生物科技有限公司 | Skin tightening composition and application thereof, skin tightening essence and preparation method thereof |
| CN110711171A (en) * | 2019-11-03 | 2020-01-21 | 上海悦目化妆品有限公司 | Mirror cream with wrinkle removing and repairing effects |
| CN111329784A (en) * | 2020-04-02 | 2020-06-26 | 广州市逸轩精细化工有限公司 | Wrinkle-removing essence cream and preparation method thereof |
| CN111529428A (en) * | 2020-06-17 | 2020-08-14 | 上海佐姿美容化妆品有限公司 | Wrinkle removing cosmetic containing hydrolyzed collagen derived from fish skin |
| CN114555043A (en) * | 2019-08-21 | 2022-05-27 | 株式会社Lg生活健康 | Cosmetic composition comprising a eutectic mixture |
| CN114588062A (en) * | 2022-03-14 | 2022-06-07 | 富丽诗(厦门)健康科技有限公司 | Essence for facial care matched with 5D carved fascia therapy |
| CN115670982A (en) * | 2022-11-25 | 2023-02-03 | 南京科技职业学院 | Essential oil-containing liquid crystal hand cream and preparation method thereof |
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| CN109875913A (en) * | 2019-04-04 | 2019-06-14 | 广州丽彦妆生物科技有限公司 | A kind of look tired rescue stoste and preparation method thereof |
| CN110115699A (en) * | 2019-04-16 | 2019-08-13 | 上海悦目化妆品有限公司 | A kind of eye essence and preparation method thereof |
| CN114555043A (en) * | 2019-08-21 | 2022-05-27 | 株式会社Lg生活健康 | Cosmetic composition comprising a eutectic mixture |
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| CN114555043B (en) * | 2019-08-21 | 2024-04-12 | 株式会社Lg生活健康 | Cosmetic composition comprising a eutectic mixture |
| CN110613662A (en) * | 2019-10-22 | 2019-12-27 | 广东密尚生物科技有限公司 | Skin tightening composition and application thereof, skin tightening essence and preparation method thereof |
| CN110711171A (en) * | 2019-11-03 | 2020-01-21 | 上海悦目化妆品有限公司 | Mirror cream with wrinkle removing and repairing effects |
| CN111329784A (en) * | 2020-04-02 | 2020-06-26 | 广州市逸轩精细化工有限公司 | Wrinkle-removing essence cream and preparation method thereof |
| CN111529428A (en) * | 2020-06-17 | 2020-08-14 | 上海佐姿美容化妆品有限公司 | Wrinkle removing cosmetic containing hydrolyzed collagen derived from fish skin |
| CN114588062A (en) * | 2022-03-14 | 2022-06-07 | 富丽诗(厦门)健康科技有限公司 | Essence for facial care matched with 5D carved fascia therapy |
| CN115670982A (en) * | 2022-11-25 | 2023-02-03 | 南京科技职业学院 | Essential oil-containing liquid crystal hand cream and preparation method thereof |
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