CN109303743A

CN109303743A - Chinese medicine composition is preparing the application in skin care item

Info

Publication number: CN109303743A
Application number: CN201811394262.5A
Authority: CN
Inventors: 龙致科; 胡永志; 李秋芳; 黄柳云; 海慧清
Original assignee: LIUZHOU LMZ CO Ltd
Current assignee: LIUZHOU LMZ CO Ltd
Priority date: 2018-11-21
Filing date: 2018-11-21
Publication date: 2019-02-05
Anticipated expiration: 2038-11-21
Also published as: CN109303743B

Abstract

The invention discloses Chinese medicine compositions to prepare the application in skin care item, it is related to oral care techniques field, it is added in skin care item i.e. in the technique for preparing skin care item using compound Chinese medicine extract as the sole active agent of effects of antiinflammation and bacteriostasis, the compound Chinese medicine extract is Duanxueliu extract, perilla leaf extract, Herba Patriniae extract, Artemisinin, glabrous sarcandra herb extract, Millettia extract, phellodendron extract, Herba siegesbeckiae extract, Herba Lycopodii extract, cinnamomum cassia extract, Ginger P.E, its mass ratio is 2:5:2:2:3:2:3:2:2:1:1, safety is not used only in Chinese medicine composition, and there is heat clearing and inflammation relieving bacteriostasis efficacy, not only alleviate sore rash, antiallergy, cool blood, anti-inflammatory, antibacterial bacterium, the irritation of product is reduced simultaneously, it is unbalance to be not easy to cause skin micro-ecological environment, There is adjusting and protective effect to skin, and safely and effectively, it can be simple for production with routine use.

Description

Chinese medicine composition is preparing the application in skin care item

Technical field

The present invention relates to washing product technical field, especially a kind of skin care item with clearing heat and cooling blood degerming.

Background technique

With the continuous improvement of living standards, people increasingly focus on the maintenance of autologous skin, and skin care item have become each The necessity of family.Especially for vast female consumer, skin care item why can skin care be because wherein containing big The nutritional ingredient of amount, but be easier to breed bacterium when being coated with skin care item on the skin of people, and the growth of bacterium is easy to Cause dermatitis and skin allergy；In addition the chemical raw material in skin care item may also cause allergy because of long-time contact skin Shape.Although all containing a certain amount of preservative, these product matter used that can only guarantee not break a seal in present skin care item Amount, and preservative itself has very big irritation and sensitization to skin.Later, people after study, improve, in skin care item The middle various Chinese herbal medicines of addition, to reach anti-inflammatory, antianaphylactic purpose；But the Chinese herbal medicine collocation of many skin care item is unreasonable or selects It is improper to select, and anti-inflammatory, antiallergic effect are not obvious.

Summary of the invention

Problems solved by the invention is to provide Chinese medicine composition and is preparing the application scheme in skin care item, this skin care item tool There are apparent anti-inflammatory, bacteriostasis.

Chinese medicine composition of the invention is exactly to incite somebody to action in the technique for preparing skin care item preparing the application scheme in skin care item Compound Chinese medicine extract is added in skin care item as the sole active agent of effects of antiinflammation and bacteriostasis, and the compound Chinese medicine extract is Duanxueliu extract, perilla leaf extract, Herba Patriniae extract, Artemisinin, glabrous sarcandra herb extract, Millettia extract, Phellodendron extract, Herba siegesbeckiae extract, Herba Lycopodii extract, cinnamomum cassia extract, Ginger P.E, the Duanxueliu extract, Perilla leaf extract, Herba Patriniae extract, Artemisinin, glabrous sarcandra herb extract, Millettia extract, phellodendron extract, pig Xian grass extract, Herba Lycopodii extract, cinnamomum cassia extract, Ginger P.E mass ratio be 2:5:2:2:3:2:3:2:2:1:1.

In above-mentioned technical proposal, more specific scheme may also is that the Duanxueliu extract, perilla leaf extract, lose Sauce grass extract, glabrous sarcandra herb extract, Millettia extract, phellodendron extract, Herba siegesbeckiae extract, stretches muscle at Artemisinin Careless extract, cinnamomum cassia extract, Ginger P.E in preparing moisturizing hydraulic art as the sole active of effects of antiinflammation and bacteriostasis at Point, the Duanxueliu extract, perilla leaf extract, Herba Patriniae extract, Artemisinin, glabrous sarcandra herb extract, Caulis Spatholobi Extract, phellodendron extract, Herba siegesbeckiae extract, Herba Lycopodii extract, cinnamomum cassia extract, Ginger P.E are in lotion raw material In weight percent be 10~80%.

It is further: the Duanxueliu extract, perilla leaf extract, Herba Patriniae extract, Artemisinin, Glabrous Sarcandra Herb Extract, Millettia extract, phellodendron extract, Herba siegesbeckiae extract, Herba Lycopodii extract, cinnamomum cassia extract, ginger extract As the sole active agent of effects of antiinflammation and bacteriostasis in preparing milky lotion technique, the Duanxueliu extract, perilla leaf mention object Object, Herba Patriniae extract, Artemisinin, glabrous sarcandra herb extract, Millettia extract, phellodendron extract, Common St.Paulswort Herb is taken to extract Object, Herba Lycopodii extract, cinnamomum cassia extract, weight percent of the Ginger P.E in moisturizing dairy milk starting material are 4~40%.

Further, the Duanxueliu extract, perilla leaf extract, Herba Patriniae extract, Artemisinin, Glabrous Sarcandra Herb Extract, Millettia extract, phellodendron extract, Herba siegesbeckiae extract, Herba Lycopodii extract, cinnamomum cassia extract, ginger extract As the sole active agent of effects of antiinflammation and bacteriostasis in preparing skin cream technique, the Duanxueliu extract, perilla leaf mention object Object, Herba Patriniae extract, Artemisinin, glabrous sarcandra herb extract, Millettia extract, phellodendron extract, Common St.Paulswort Herb is taken to extract Object, Herba Lycopodii extract, cinnamomum cassia extract, weight percent of the Ginger P.E in skin cream raw material are 2~20%.

Clinopodium polycephalum of the present invention is Lamiaceae plant Chinese lantern (Cliruo podium polycephalum (Vani-ot) C.Y.Wu et Hsuan) or calamint (Clinopodium chinense (Benth) Q.Kuntze) drying Aerial part, extract have effects that astringing to arrest bleeding, cooling and activating blood.

Perilla leaf of the present invention is the leaf of Lamiaceae plant purple perilla (Perilla frutescens (L.) Britt.) Piece part, extract contain the chemical components such as cinnaldehydrum and other phenols, organic acid, glycoside, have sweating expelling pathogenic factors from muscles and skin, warm promoting menstruation The effect of arteries and veins, and can it is antibacterial, hemostasis, it is anti-oxidant the effects of.

Field pennycress of the present invention, for patrinia herb patrinia scabiosaefolia Fiscs (Patrinia scabiosaefolia Fisch) Or the herb part of patrima villosa (Patrinia villosa Juss), extract have it is clearing heat and detoxicating, it is removing blood stasis and expelling pus, clear Sore analgesic and other effects, and play the role of antibacterial and antiviral.

Sweet wormwood of the present invention is on the dry ground of compositae plant artemisia annua (Artemisia carvifolia L.) Part, extract have effects that clearing heat and cooling blood, clear hot summer weather, preventing malaria；And have good resisting pathogenic microbes, antiendotoxin, The effects of antibacterial anti-inflammatory；Its volatile oil also has killing effect to skin tinea.

Glabrous Sarcandra Herb of the present invention is gold Li Lanke Chloranthus glaber (Sarcandra glabra (Thunb.) Nakai) Dry herb, extract have effects that clearing heat and cooling blood, promoting blood circulation ecchymose removing, dispelling wind and removing obstruction in the meridians；And have good antibacterial, it is antiviral, Anti-inflammatory effect.

Caulis Spatholobi of the present invention is the dry of leguminous plant spatholobus suberectus (Spatholobus suberectus Dunn) Dry rhizome, extract have effects that blood circulation promoting and enriching, menstruction regulating and pain relieving, relaxing tendons and activating collaterals；And there is anti-inflammatory and adjusting immune system Effect.

Cortex Phellodendri of the present invention is the dry of Rutaceae wampee (Phellodendron chinense Schneid.) Dry bark, extract have effects that heat-clearing and damp-drying drug, detoxification sore treatment, purging intense heat, except steaming；And there are resisting pathogenic microbes, anti-inflammatory, solution The effects of hot, anti-oxidant, antiulcer.

This invention Suo Shu Common St.Paulswort Herb is composite family Zhi Wu pig Xian (Siegesbeckia orientalis L.), Xian Geng pig Xian (Siegesbeckia pubescens Makino) or siegesbeckia glabrescens Makino (Siegesbeckia glabrescens Makino) Dry aerial parts, extract has effects that clearing heat and detoxicating, wind-damp dispelling, sharp joint；And have anti-inflammatory, anti-herpesvirus, The effect of antibacterial.

Lycopodium calvatum of the present invention is the dry of lycopsid lycopod (Lycopodium jaPonicum Thunb.) Dry herb, extract have effects that dispelling wind and eliminating dampness, relaxing tendons and activating collaterals；And there are antibacterial, anti-inflammatory, analgesia, oxidation resistant effect.

Cortex cinnamomi of the present invention is the dry bark of lauraceae plant cortex cinnamomi (Cinnamomum cassia Presl), Extract has effects that mends fire supporing yang, guiding fire to origin, eliminating cold to stop pain, warming meridian；And there is antipyretic, analgesic effect.

Ginger of the present invention is the fresh rhizome of zingiber (Zingiber officinale Rosc.), Extract has effects that inducing sweat and dispelling exogenous evils；And have the effects that anti-inflammatory, antipyretic, antibacterial analgesia, antiulcer well.

The extracting method of Chinese medicine of the present invention are as follows: the Chinese medical extract is extracted using ethyl alcohol, by obtaining Chinese medical extract: mixed Crude drug=1:2-1:5 mass ratio is closed to extract.

Above-mentioned Chinese medicine composition be joined in skin care item product preparation process of the invention as active constituent, there is heat-clearing Anti-inflammatory bacteriostasis efficacy not only alleviates sore rash, antiallergy, cool blood, anti-inflammatory, antibacterial bacterium, while reducing the irritation of product, is not easy to draw It is unbalance to play skin micro-ecological environment, there is adjusting and protective effect to skin, and safely and effectively, can be made with routine use It is easy.

Specific embodiment

Below with reference to embodiment, the present invention will be further described, in following examples, related percentage unless It is otherwise noted, is calculated in weight percent.

Lotion constitutive material and weight percent content such as table 1 of the embodiment 1 into embodiment 6:

In following examples, in Chinese medicine anti-inflammatory antipathogenic composition, each Chinese medical extract is Duanxueliu extract, perilla leaf extraction Object, Herba Patriniae extract, Artemisinin, glabrous sarcandra herb extract, Millettia extract, phellodendron extract, Herba siegesbeckiae extract, Herba Lycopodii extract, cinnamomum cassia extract, Ginger P.E are in preparing moisturizing hydraulic art as unique work of effects of antiinflammation and bacteriostasis Property ingredient, the Duanxueliu extract, perilla leaf extract, Herba Patriniae extract, Artemisinin, glabrous sarcandra herb extract, chicken Blood boisiana extract, phellodendron extract, Herba siegesbeckiae extract, Herba Lycopodii extract, cinnamomum cassia extract, Ginger P.E, embodiment 1 In, the ratio of each Chinese medical extract are as follows: 0:0:0:0:0:0:0:0:0:0:0；In embodiment 2~4, the ratio of each Chinese medical extract By said sequence are as follows: 2:5:2:2:3:2:3:2:2:1:1；In embodiment 5, the ratio of each Chinese medical extract presses said sequence are as follows: 2:5:2:2:3:2:0:2:0:1:1；In embodiment 6, the ratio of each Chinese medical extract presses said sequence are as follows: 2:5:2:2:0:0:3: 2:2:1:1；

Table 1:

Milky lotion constitutive material and weight percent content such as table 2 of the embodiment 7 into embodiment 12:

In following examples, each Chinese medical extract is blood flow extract, perilla leaf extract, loses in Chinese medicine anti-inflammatory anti-itch ingredient Sauce grass extract, glabrous sarcandra herb extract, Millettia extract, phellodendron extract, Herba siegesbeckiae extract, stretches muscle at Artemisinin The sole active agent of careless extract, cinnamomum cassia extract, Ginger P.E in preparing perfumed soap technique as anti-inflammatory anti-itch effect, The Duanxueliu extract, perilla leaf extract, Herba Patriniae extract, Artemisinin, glabrous sarcandra herb extract, Caulis Spatholobi are extracted Object, phellodendron extract, Herba siegesbeckiae extract, Herba Lycopodii extract, cinnamomum cassia extract, Ginger P.E, in embodiment 7, it is each in The ratio of medicament extract are as follows: 0:0:0:0:0:0:0:0:0:0:0；In embodiment 8~10, the ratio of each Chinese medical extract is by above-mentioned Sequentially are as follows: 2:5:2:2:3:2:3:2:2:1:1；In embodiment 11, the ratio of each Chinese medical extract presses said sequence are as follows: 2:5:2: 2:3:2:0:2:0:1:1；In embodiment 12, the ratio of each Chinese medical extract presses said sequence are as follows: 2:5:2:2:0:0:3:2:2: 1:1；

Table 2:

Skin cream constitutive material and weight percent content such as table 3 of the embodiment 13 into embodiment 18:

In following examples, each Chinese medical extract is blood flow extract, perilla leaf extract, loses in Chinese medicine anti-inflammatory anti-itch ingredient Sauce grass extract, glabrous sarcandra herb extract, Millettia extract, phellodendron extract, Herba siegesbeckiae extract, stretches muscle at Artemisinin The sole active agent of careless extract, cinnamomum cassia extract, Ginger P.E in preparing perfumed soap technique as anti-inflammatory anti-itch effect, The Duanxueliu extract, perilla leaf extract, Herba Patriniae extract, Artemisinin, glabrous sarcandra herb extract, Caulis Spatholobi are extracted Object, phellodendron extract, Herba siegesbeckiae extract, Herba Lycopodii extract, cinnamomum cassia extract, Ginger P.E, in embodiment 13, it is each in The ratio of medicament extract are as follows: 0:0:0:0:0:0:0:0:0:0:0；In embodiment 14~16, the ratio of each Chinese medical extract is by upper State sequence are as follows: 2:5:2:2:3:2:3:2:2:1:1；In embodiment 17, the ratio of each Chinese medical extract presses said sequence are as follows: 2:5: 2:2:3:2:0:2:0:1:1；In embodiment 18, the ratio of each Chinese medical extract presses said sequence are as follows: 2:5:2:2:0:0:3:2: 2:1:1；

Table 3:

Clinical trial part:

1, bacteriostatic experiment (by bacteriostasis rate method test in " Disposable Sanitary Accessory sanitary standard " GB15979), as a result such as Table 4:

The result shows that in embodiment 2-4, embodiment 8-10 and embodiment 14-16, compound Chinese medicine extract and matched with the extract Manufactured skin care item have good inhibiting effect to staphylococcus aureus and excrement colibacillus group, with compound Chinese medicine extract Ratio increases, and bacteriostasis is more obvious；In embodiment 5,6,10,11,17,18, mentioned in the herbal mixture for taking same percentage Object is taken, but every kind of Chinese medical extract has lacked one or two taste Chinese medical extract therein, to staphylococcus aureus and excrement large intestine The inhibiting effect of flora is relatively low.

2, anti-inflammatory effect is tested

The zoopery of anti-inflammatory anti-itch skin care item

Experimental animal: small white mouse, 18-22g of weight.

Test drug: Fluonex；The embodiment 1 of this patent, embodiment 4, embodiment 7, is implemented embodiment 2 The sample of example 8, embodiment 13, embodiment 16, embodiment 5, embodiment 10, embodiment 17.

Test method: the anti-inflammatory effect of paraxylene cause small white mouse auricle acute inflammation swelling.

As a result such as table 5:

The experimental results showed that the sample of embodiment 2,4,8,16 has apparent anti-inflammatory effect, embodiment 1,7 and embodiment 13 (being not added with traditional Chinese medicine ingredients) anti-inflammatory effect is weak, and embodiment 5, embodiment 10 and embodiment 17 are in the compound for taking same percentage Medicament extract, but every kind of compound Chinese medicine extract has lacked one or two taste Chinese medical extract therein, and anti-inflammatory effect is weaker.

3, itching-relieving action is tested

The zoopery of anti-inflammatory anti-itch skin care item

Experimental animal: Hartley cavy, 250-400g of weight.

Test drug: San Wei Qing Re Zhi Yang Xiji；Embodiment 1, embodiment 2, embodiment 4, embodiment 6, the reality of this patent Apply the sample of example 8, embodiment 10, embodiment 12, embodiment 14, embodiment 16, embodiment 18.

Test method: the influence to the antipruritic reaction of Hartley cavy histamine phosphate.

As a result such as table 6:

The experimental results showed that embodiment 2,4,8,16 has an apparent itching-relieving action, embodiment 1,7,13(be not added with Chinese medicine at Point) having no obvious itching-relieving action, embodiment 6, embodiment 11, embodiment 17 take the compound Chinese medicine extract of same percentage, But every kind of Chinese medical extract has lacked one or two taste Chinese medical extract therein, and itching-relieving action is weaker.

Summarize: 11 taste Chinese medical extracts of the invention are correctly used in skin care item necessarily to scale, have lacked any taste, Its anti-inflammatory antipruritic, antibacterial does not reach requirement.

Claims

1. Chinese medicine composition is preparing the application in skin care item, i.e., compound Chinese medicine extract is made in the technique for preparing skin care item It is added in skin care item for the sole active agent of effects of antiinflammation and bacteriostasis, the compound Chinese medicine extract is Duanxueliu extract, purple Perilla leaf extract, Herba Patriniae extract, Artemisinin, glabrous sarcandra herb extract, Millettia extract, phellodendron extract, pig Xian Careless extract, Herba Lycopodii extract, cinnamomum cassia extract, Ginger P.E, the Duanxueliu extract, lose perilla leaf extract Sauce grass extract, glabrous sarcandra herb extract, Millettia extract, phellodendron extract, Herba siegesbeckiae extract, stretches muscle at Artemisinin Careless extract, cinnamomum cassia extract, Ginger P.E mass ratio be 2:5:2:2:3:2:3:2:2:1:1.

2. Chinese medicine composition according to claim 1 is preparing the application in skin care item, it is characterised in that: the clinopodium polycephalum Extract, perilla leaf extract, Herba Patriniae extract, Artemisinin, glabrous sarcandra herb extract, Millettia extract, Cortex Phellodendri mention It takes object, Herba siegesbeckiae extract, Herba Lycopodii extract, cinnamomum cassia extract, Ginger P.E to be used as in preparing moisturizing hydraulic art to disappear The sole active agent of scorching bacteriostasis, the Duanxueliu extract, perilla leaf extract, Herba Patriniae extract, sweet wormwood extract Object, glabrous sarcandra herb extract, Millettia extract, phellodendron extract, Herba siegesbeckiae extract, Herba Lycopodii extract, cinnamomum cassia extract, Weight percent of the Ginger P.E in lotion raw material is 10~80%.

3. Chinese medicine composition according to claim 1 is preparing the application in skin care item, it is characterised in that: the clinopodium polycephalum Extract, perilla leaf extract, Herba Patriniae extract, Artemisinin, glabrous sarcandra herb extract, Millettia extract, Cortex Phellodendri mention It takes Wu, Herba siegesbeckiae extract, Herba Lycopodii extract, cinnamomum cassia extract, Ginger P.E to be used as in preparing milky lotion technique to disappear The sole active agent of scorching bacteriostasis, the Duanxueliu extract, perilla leaf extract, Herba Patriniae extract, sweet wormwood extract Object, glabrous sarcandra herb extract, Millettia extract, phellodendron extract, Herba siegesbeckiae extract, Herba Lycopodii extract, cinnamomum cassia extract, Weight percent of the Ginger P.E in moisturizing dairy milk starting material is 4~40%.

4. Chinese medicine composition according to claim 1 is preparing the application in skin care item, it is characterised in that: the clinopodium polycephalum Extract, perilla leaf extract, Herba Patriniae extract, Artemisinin, glabrous sarcandra herb extract, Millettia extract, Cortex Phellodendri mention It takes Wu, Herba siegesbeckiae extract, Herba Lycopodii extract, cinnamomum cassia extract, Ginger P.E to be used as in preparing skin cream technique to disappear The sole active agent of scorching bacteriostasis, the Duanxueliu extract, perilla leaf extract, Herba Patriniae extract, sweet wormwood extract Object, glabrous sarcandra herb extract, Millettia extract, phellodendron extract, Herba siegesbeckiae extract, Herba Lycopodii extract, cinnamomum cassia extract, Weight percent of the Ginger P.E in skin cream raw material is 2~20%.