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CN109157204A - A kind of no cuff type wrist artery blood pressure measuring method and system - Google Patents

A kind of no cuff type wrist artery blood pressure measuring method and system Download PDF

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Publication number
CN109157204A
CN109157204A CN201810892505.1A CN201810892505A CN109157204A CN 109157204 A CN109157204 A CN 109157204A CN 201810892505 A CN201810892505 A CN 201810892505A CN 109157204 A CN109157204 A CN 109157204A
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blood pressure
gauger
dbp
sbp
module
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郭承军
何全艺
吕江婷
马建华
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Sichuan Zhizhuo Science And Technology Co Ltd
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Sichuan Zhizhuo Science And Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021Measuring pressure in heart or blood vessels
    • A61B5/02108Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021Measuring pressure in heart or blood vessels
    • A61B5/02108Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics
    • A61B5/02116Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics of pulse wave amplitude

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
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  • Biophysics (AREA)
  • Pathology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)

Abstract

The invention discloses a kind of no cuff type wrist artery blood pressure measuring methods, comprising the following steps: calculates gauger's characteristic index array (HR, PIR, PTT) relevant to blood pressure calculating;The verification of arterial pressure is carried out to the wrist of gauger, measure the reference pressure value (SBP of gauger, DBP), by reference to pressure value (SBP,) and characteristic index array (HR DBP, PIR, PTT) building blood pressure computation model, complete the calculating and preservation of blood pressure checkout coefficient in gauger's blood pressure computation model;The blood pressure checkout coefficient of gauger is obtained, the current characteristic index array (HR, PIR, PTT) of gauger is obtained, and calculates the pressure value (SBP, DBP) at gauger's current time according to blood pressure computation model.The invention also discloses a kind of no cuff type wrist artery blood pressure measuring system, the present invention improves the computational accuracy of wrist artery blood pressure, is particularly suitable for the intelligent wearable device of wrist.

Description

A kind of no cuff type wrist artery blood pressure measuring method and system
Technical field
The present invention relates to blood pressure measurement technical field, especially a kind of no cuff type wrist artery blood pressure measuring method and it is System.
Background technique
Blood pressure measuring method can be divided into the invasive direct method of measurement and the noninvasive indirect method of measurement, not due to the invasive direct method of measurement Only technical requirements are high, and are difficult to repeatedly measure, and are only applicable to the clinical blood pressure measurement for jeopardizing major operation patient again;Compare and Speech, the noninvasive indirect method of measurement are more widely applied because it is more simple and easy to do.It is common at this stage noninvasive indirect Measurement blood pressure method have: stethoscopy, oscillographic method, angiosthenia method etc., however these measurement methods in actual use there is Various defects, such as: stethoscopy and oscillographic method need to pressurize using cuff, can bring very big sense of discomfort to gauger, and artery The sensor that tensammetry uses has high sensitivity to displacement, requires measuring device and measurement position all harsher.
In recent years, in order to overcome the problems of existing blood pressure measurement technology, many those skilled in the art are proposed It is various to be based on pulse wave (PPG) with electrocardiogram (ECG) signal without cuff blood pressure measuring method, and it is applied to various intelligence On energy wearable device (such as Intelligent bracelet, smartwatch).However, the people that intelligent wearable device measurement on the market obtains at present The anti-interference ability of body blood pressure accuracy rate and entirety is all also urgently promoted.
Summary of the invention
To solve problems of the prior art, the purpose of the present invention is obtained based on PPG with ECG signal for existing Pulse wave transmission time without cuff blood pressure measuring method accuracy rate and the problem of poor anti jamming capability, a kind of no cuff type is provided Wrist blood pressure measurement method and device.
To achieve the above object, the technical solution adopted by the present invention is that: a kind of no cuff type wrist artery blood pressure measurement side Method, comprising the following steps:
S1, gauger's characteristic index array (HR, PIR, PTT) relevant to blood pressure calculating is calculated, wherein HR, PIR, PTT The respectively heart rate of gauger, pulse wave Amplitude Ratio and pulse wave transmission time;
S2, the verification that arterial pressure is carried out to the wrist of gauger, measure the reference pressure value (SBP, DBP) of gauger, Wherein, SBP refers to that systolic pressure, DBP refer to diastolic pressure, the characteristic index number obtained by reference to pressure value (SBP, DBP) and step S1 Group (HR, PIR, PTT) constructs blood pressure computation model, completes the calculating of blood pressure checkout coefficient and guarantor in gauger's blood pressure computation model It deposits;
The blood pressure checkout coefficient for the gauger that S3, obtaining step S2 are obtained obtains the current spy of gauger using step S1 It levies index array (HR, PIR, PTT), and calculates the pressure value (SBP, DBP) at gauger's current time according to blood pressure computation model.
Preferably, the step S1 specifically includes the following steps:
S11, synchronous acquisition gauger's wrist pulse wave PPG original signal and electrocardiogram ECG original signal;
S12, respectively pulse wave PPG original signal and electrocardiogram ECG original signal are filtered to obtain filtered PPG signal And ECG signal;
S13, calculated separately by filtered PPG signal and ECG signal gauger characteristic index array (HR, PIR, PTT)。
Further, the step S2 specifically includes the following steps:
S21, one group of characteristic index array (HR, PIR, PTT) relevant to blood pressure calculating is obtained according to step S13, simultaneously The reference pressure value (SBP, DBP) to one group of gauger is measured by blood pressure measuring;
S22, step S21 is repeated, obtains at least 4 groups of characteristic index arrays (HR, PIR, PTT) and corresponding with reference to pressure value (SBP, DBP);
S23, according to the obtained multi-group data of S22 and blood pressure computation model, carry out linear regression analysis respectively, calculate survey The blood pressure checkout coefficient of amount person simultaneously saves;The blood pressure computation model are as follows:Wherein, (as, bs, cs) is the verification system of SBP Number, (ad, bd, cd, dd) are the checkout coefficient of DBP.
Further, the step S3 specifically includes the following steps:
The blood pressure checkout coefficient of the gauger saved in S31, obtaining step S23: SBP corresponding (as, bs, cs) and DBP Corresponding (ad, bd, cd, dd);
S32, according to step S13 obtain gauger's current time characteristic index array relevant to blood pressure calculating (HR, PIR, PTT);
S32, according to blood pressure computation model: Calculate the pressure value (SBP, DBP) at output gauger's current time.
The present invention also provides a kind of no cuff type wrist artery blood pressure measuring systems, comprising: signal acquisition module, verification ginseng Examine blood pressure input module and control module;
The signal acquisition module includes PPG signal acquisition module and ECG signal acquisition module, wherein PPG signal acquisition Module is for acquiring pulse wave PPG original signal, and ECG signal acquisition module is for acquiring electrocardiogram ECG original signal;
The verification with reference to blood pressure input module is used to measure the reference pressure value (SBP, DBP) of gauger and by its data It is input in control module;
The control module includes data filtering module, characteristic index computing module, blood pressure checkout coefficient computing module, blood Checkout coefficient memory module and blood pressure computing module are pressed, specific:
The data filtering module includes PPG signal filter module and ECG signal filter module, wherein the filtering of PPG signal Module is for being filtered pulse wave PPG original signal, and ECG signal filter module is for being filtered ECG original signal;
The characteristic index computing module includes being counted respectively according to filtered PPG signal and filtered ECG signal The HR computing module, PIR computing module and PTT for calculating heart rate HR, pulse wave Amplitude Ratio PIR and pulse wave transmission time PTT calculate Module;
Multiple groups of the blood pressure checkout coefficient computing module according to verification with reference to the input of blood pressure input module refer to pressure value (SBP, DBP) and pressure value (SBP, DBP) corresponding characteristic index array (HR, PIR, PTT) is referred to multiple groups, is returned using linear Return the blood pressure checkout coefficient for calculating gauger and is saved in the blood pressure checkout coefficient memory module;
The blood pressure computing module includes SBP computing module and DBP computing module, for being stored according to blood pressure checkout coefficient The blood pressure checkout coefficient of gauger and current characteristic index array (HR, PIR, PTT) calculate the current blood of gauger in module Pressure value (SBP, DBP).
Preferably, this further includes display module without cuff type wrist artery blood pressure measuring system, for showing the survey measured The current pressure value of amount person (SBP, DBP).
The beneficial effects of the present invention are:
1, other overwhelming majority are compared based on PPG+ECG signal, only calculate blood pressure (SBP, DBP) by calculating PTT Method, the present invention are directed to wrist artery blood pressure measurement, and in combination with HR, PIR and PTT index establishes more reasonable sphygmomanometer It calculates model and improves the computational accuracy of wrist artery blood pressure to calculate gauger's blood pressure, be particularly suitable for the intelligence wearing of wrist Equipment.
2, it according to different gaugers, carries out verification calculating and saves corresponding blood pressure checkout coefficient, improve blood pressure calculating The versatility and accuracy of model.
3, data filtering is carried out to the original PPG and ECG signal of acquisition, improves the system and verifies and measured in blood pressure Anti-interference ability in journey.
4, it for different gaugers, needs to complete a blood pressure verification, saves corresponding checkout coefficient, then carry out blood pressure Measurement;And to each gauger, it also only needs to carry out a blood pressure verification, multiple blood pressure measurement can be carried out.
Detailed description of the invention
Fig. 1 is the structural block diagram of blood pressure measuring system of the embodiment of the present invention;
Fig. 2 is the process that characteristic index array (HR, PIR, PTT) relevant to blood pressure calculating is obtained in the embodiment of the present invention Block diagram.
Specific embodiment
The embodiment of the present invention is described in detail with reference to the accompanying drawing.
Embodiment
A kind of no cuff type wrist artery blood pressure measuring method, comprising the following steps:
S1, gauger's characteristic index array (HR, PIR, PTT) relevant to blood pressure calculating is calculated, wherein HR, PIR, PTT The respectively heart rate of gauger, pulse wave Amplitude Ratio and pulse wave transmission time;
S2, the verification that arterial pressure is carried out to the wrist of gauger, measure the reference pressure value (SBP, DBP) of gauger, Wherein, SBP refers to that systolic pressure, DBP refer to diastolic pressure, the characteristic index number obtained by reference to pressure value (SBP, DBP) and step S1 Group (HR, PIR, PTT) constructs blood pressure computation model, completes the calculating of blood pressure checkout coefficient and guarantor in gauger's blood pressure computation model It deposits;
The blood pressure checkout coefficient for the gauger that S3, obtaining step S2 are obtained obtains the current spy of gauger using step S1 It levies index array (HR, PIR, PTT), and calculates the pressure value (SBP, DBP) at gauger's current time according to blood pressure computation model.
As shown in Fig. 2, the step S1 specifically includes the following steps:
S11, synchronous acquisition gauger's wrist pulse wave PPG original signal and electrocardiogram ECG original signal;
S12, respectively pulse wave PPG original signal and electrocardiogram ECG original signal are filtered to obtain filtered PPG signal And ECG signal;
S13, calculated separately by filtered PPG signal and ECG signal gauger characteristic index array (HR, PIR, PTT)。
The step S2 specifically includes the following steps:
S21, one group of characteristic index array (HR, PIR, PTT) relevant to blood pressure calculating is obtained according to step S13, simultaneously The reference pressure value (SBP, DBP) to one group of gauger is measured by blood pressure measuring;
S22, step S21 is repeated, obtains at least 4 groups of characteristic index arrays (HR, PIR, PTT) and corresponding with reference to pressure value (SBP, DBP);
S23, according to the obtained multi-group data of S22 and blood pressure computation model, carry out linear regression analysis respectively, calculate survey The blood pressure checkout coefficient of amount person simultaneously saves;The blood pressure computation model are as follows:Wherein, (as, bs, cs) is the verification system of SBP Number, (ad, bd, cd, dd) are the checkout coefficient of DBP.
The step S3 specifically includes the following steps:
The blood pressure checkout coefficient of the gauger saved in S31, obtaining step S23: SBP corresponding (as, bs, cs) and DBP Corresponding (ad, bd, cd, dd);
S32, according to step S13 obtain gauger's current time characteristic index array relevant to blood pressure calculating (HR, PIR, PTT);
S32, according to blood pressure computation model: Calculate the pressure value (SBP, DBP) at output gauger's current time.
A kind of no cuff type wrist artery blood pressure measuring system, (in Fig. 1, blood is marked in solid arrows as shown in Figure 1 The measurement procedure of blood pressure is marked in the checking process of pressure, heavy solid line arrows), comprising: signal acquisition module, verification are defeated with reference to blood pressure Enter module and control module;
The signal acquisition module includes PPG signal acquisition module and ECG signal acquisition module, wherein PPG signal acquisition Module is for acquiring pulse wave PPG original signal, and ECG signal acquisition module is for acquiring electrocardiogram ECG original signal;
The verification with reference to blood pressure input module is used to measure the reference pressure value (SBP, DBP) of gauger and by its data It is input in control module;
The control module includes data filtering module, characteristic index computing module, blood pressure checkout coefficient computing module, blood Checkout coefficient memory module and blood pressure computing module are pressed, specific:
The data filtering module includes PPG signal filter module and ECG signal filter module, wherein the filtering of PPG signal Module is for being filtered pulse wave PPG original signal, and ECG signal filter module is for being filtered ECG original signal;
The characteristic index computing module includes being counted respectively according to filtered PPG signal and filtered ECG signal The HR computing module, PIR computing module and PTT for calculating heart rate HR, pulse wave Amplitude Ratio PIR and pulse wave transmission time PTT calculate Module;
Multiple groups of the blood pressure checkout coefficient computing module according to verification with reference to the input of blood pressure input module refer to pressure value (SBP, DBP) and pressure value (SBP, DBP) corresponding characteristic index array (HR, PIR, PTT) is referred to multiple groups, is returned using linear Return the blood pressure checkout coefficient for calculating gauger and is saved in the blood pressure checkout coefficient memory module;
The blood pressure computing module includes SBP computing module and DBP computing module, for being stored according to blood pressure checkout coefficient The blood pressure checkout coefficient of gauger and current characteristic index array (HR, PIR, PTT) calculate the current blood of gauger in module Pressure value (SBP, DBP).
This further includes display module without cuff type wrist artery blood pressure measuring system in one of the embodiments, is used for Show the current pressure value (SBP, DBP) of the gauger measured.
A specific embodiment of the invention above described embodiment only expresses, the description thereof is more specific and detailed, but simultaneously Limitations on the scope of the patent of the present invention therefore cannot be interpreted as.It should be pointed out that for those of ordinary skill in the art For, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to guarantor of the invention Protect range.

Claims (6)

1. a kind of no cuff type wrist artery blood pressure measuring method, which comprises the following steps:
S1, gauger's characteristic index array (HR, PIR, PTT) relevant to blood pressure calculating is calculated, wherein HR, PIR, PTT difference For the heart rate, pulse wave Amplitude Ratio and pulse wave transmission time of gauger;
S2, the verification that arterial pressure is carried out to the wrist of gauger, measure the reference pressure value (SBP, DBP) of gauger, wherein SBP refers to that systolic pressure, DBP refer to diastolic pressure, the characteristic index array that is obtained by reference to pressure value (SBP, DBP) and step S1 (HR, PIR, PTT) building blood pressure computation model, complete the calculating and preservation of blood pressure checkout coefficient in gauger's blood pressure computation model;
The blood pressure checkout coefficient for the gauger that S3, obtaining step S2 are obtained obtains the current feature of gauger using step S1 and refers to It marks array (HR, PIR, PTT), and calculates the pressure value (SBP, DBP) at gauger's current time according to blood pressure computation model.
2. no cuff type wrist artery blood pressure measuring method according to claim 1, which is characterized in that the step S1 tool Body the following steps are included:
S11, synchronous acquisition gauger's wrist pulse wave PPG original signal and electrocardiogram ECG original signal;
S12, respectively to pulse wave PPG original signal and electrocardiogram ECG original signal filter to obtain filtered PPG signal and ECG signal;
S13, the characteristic index array (HR, PIR, PTT) that gauger is calculated separately by filtered PPG signal and ECG signal.
3. no cuff type wrist artery blood pressure measuring method according to claim 2, which is characterized in that the step S2 tool Body the following steps are included:
S21, one group of characteristic index array (HR, PIR, PTT) relevant to blood pressure calculating is obtained according to step S13, passed through simultaneously Blood pressure measuring measures the reference pressure value (SBP, DBP) to one group of gauger;
S22, step S21 is repeated, obtains at least 4 groups of characteristic index arrays (HR, PIR, PTT) and corresponding with reference to pressure value (SBP, DBP);
S23, according to the obtained multi-group data of S22 and blood pressure computation model, carry out linear regression analysis respectively, calculate gauger Blood pressure checkout coefficient and save;The blood pressure computation model are as follows:Wherein, (as, bs, cs) is the verification system of SBP Number, (ad, bd, cd, dd) are the checkout coefficient of DBP.
4. no cuff type wrist artery blood pressure measuring method according to claim 3, which is characterized in that the step S3 tool Body the following steps are included:
The blood pressure checkout coefficient of the gauger saved in S31, obtaining step S23: SBP corresponding (as, bs, cs) is corresponding with DBP (ad, bd, cd, dd);
S32, according to step S13 obtain gauger's current time characteristic index array relevant to blood pressure calculating (HR, PIR, PTT);
S32, according to blood pressure computation model:It calculates Export the pressure value (SBP, DBP) at gauger's current time.
5. a kind of no cuff type wrist artery blood pressure measuring system characterized by comprising signal acquisition module, verification reference Blood pressure input module and control module;
The signal acquisition module includes PPG signal acquisition module and ECG signal acquisition module, wherein PPG signal acquisition module For acquiring pulse wave PPG original signal, ECG signal acquisition module is for acquiring electrocardiogram ECG original signal;
The verification is used to measure the reference pressure value (SBP, DBP) of gauger with reference to blood pressure input module and inputs its data Into control module;
The control module includes data filtering module, characteristic index computing module, blood pressure checkout coefficient computing module, blood pressure school Coefficient memory module and blood pressure computing module are tested, specific:
The data filtering module includes PPG signal filter module and ECG signal filter module, wherein PPG signal filter module For being filtered to pulse wave PPG original signal, ECG signal filter module is for being filtered ECG original signal;
The characteristic index computing module includes calculating separately the heart according to filtered PPG signal and filtered ECG signal The HR computing module of rate HR, pulse wave Amplitude Ratio PIR and pulse wave transmission time PTT, PIR computing module and PTT computing module;
The blood pressure checkout coefficient computing module according to verification with reference to blood pressure input module input multiple groups with reference to pressure value (SBP, DBP pressure value (SBP, DBP) corresponding characteristic index array (HR, PIR, PTT)) and with multiple groups is referred to, utilizes linear regression meter It calculates the blood pressure checkout coefficient of gauger and is saved in the blood pressure checkout coefficient memory module;
The blood pressure computing module includes SBP computing module and DBP computing module, for according to blood pressure checkout coefficient memory module The blood pressure checkout coefficient of middle gauger and current characteristic index array (HR, PIR, PTT) calculate the current pressure value of gauger (SBP, DBP).
6. no cuff type wrist artery blood pressure measuring system according to claim 5, which is characterized in that this is without cuff type wrist Portion's arterial blood pressure measuring system further includes display module, for showing the current pressure value of the gauger measured (SBP, DBP).
CN201810892505.1A 2018-08-07 2018-08-07 A kind of no cuff type wrist artery blood pressure measuring method and system Pending CN109157204A (en)

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CN109872820A (en) * 2019-03-29 2019-06-11 广州视源电子科技股份有限公司 Cuff-free blood pressure measuring method, cuff-free blood pressure measuring device, cuff-free blood pressure measuring equipment and storage medium
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CN112827061A (en) * 2021-02-26 2021-05-25 中山大学 Drug release control device, control method thereof, and computer-readable storage medium
CN114027810A (en) * 2021-03-31 2022-02-11 北京超思电子技术有限责任公司 Method for generating blood pressure calculation model containing arteriosclerosis classification and blood pressure measuring system
CN114027811A (en) * 2021-04-28 2022-02-11 北京超思电子技术有限责任公司 Blood pressure calculation model and blood pressure measurement system based on BImp pulse wave

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Publication number Priority date Publication date Assignee Title
CN109872820A (en) * 2019-03-29 2019-06-11 广州视源电子科技股份有限公司 Cuff-free blood pressure measuring method, cuff-free blood pressure measuring device, cuff-free blood pressure measuring equipment and storage medium
CN109872820B (en) * 2019-03-29 2023-12-08 广州视源电子科技股份有限公司 Method, device, equipment and storage medium for measuring blood pressure without cuff
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CN110292370B (en) * 2019-07-03 2020-12-15 浙江大学 Chest non-invasive blood pressure detection method based on pulse wave conduction time
CN112827061A (en) * 2021-02-26 2021-05-25 中山大学 Drug release control device, control method thereof, and computer-readable storage medium
CN114027810A (en) * 2021-03-31 2022-02-11 北京超思电子技术有限责任公司 Method for generating blood pressure calculation model containing arteriosclerosis classification and blood pressure measuring system
CN114027810B (en) * 2021-03-31 2024-03-26 北京超思电子技术有限责任公司 Blood pressure calculation model generation method containing arteriosclerosis classification and blood pressure measurement system
CN114027811A (en) * 2021-04-28 2022-02-11 北京超思电子技术有限责任公司 Blood pressure calculation model and blood pressure measurement system based on BImp pulse wave
CN114027811B (en) * 2021-04-28 2024-05-14 北京超思电子技术有限责任公司 BImp pulse wave-based blood pressure calculation model and blood pressure measurement system

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Application publication date: 20190108