CN108853702B - Novel intelligent medicine sprinkling system - Google Patents
Novel intelligent medicine sprinkling system Download PDFInfo
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- CN108853702B CN108853702B CN201810462736.9A CN201810462736A CN108853702B CN 108853702 B CN108853702 B CN 108853702B CN 201810462736 A CN201810462736 A CN 201810462736A CN 108853702 B CN108853702 B CN 108853702B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M35/00—Devices for applying media, e.g. remedies, on the human body
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/04—Skin
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- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
The invention discloses a novel intelligent medicine spraying system, which comprises: the image module consists of image acquisition equipment and a light source; a distance measurement module; the main control module consists of an image processing system, a spraying control system and a power control system; the spraying module consists of a comprehensive pressure control system, a nozzle and a liquid storage device; the sliding rail module consists of a motor and an XYZ-axis sliding rail; the intelligent medicine spraying system is constructed by adopting a plurality of modules, so that medicine damage caused by manual operation is effectively avoided, the condition of repeated spraying or missing of a spraying coverage area is avoided, meanwhile, the application prospect is wider, the price is more flexible and the intelligent medicine spraying system is more accordant with market positioning due to free collocation and selection of a plurality of modes.
Description
Technical Field
The invention relates to the biomedical industry, in particular to a novel intelligent medicine spraying system in the treatment of large-area skin defects.
Background
One of the important routes of clinical administration is transdermal administration, which is often used in particular in the treatment of large skin wounds. However, it is difficult to achieve uniform application of the drug solution by visual judgment with the naked eye in the actual administration process, and it is also difficult to judge the relationship between the severity of the wound and the amount of the drug to be administered. On the other hand, the existing coating tool can stimulate the exposed wound, increase the pain of the patient and increase the infection probability.
Disclosure of Invention
To the weak point that exists among the prior art, this case is through carrying out the innovation in coordination in medical instrument technique and medical biotechnology field, has designed a novel medicine sprinkling system, comes intelligent distribution local dose according to wound severity and total medicine volume, very big improvement the medicine utilization efficiency, adopt the low pressure pump to dose simultaneously, with the process of dosing to the amazing of wound to minimize, effectively avoid leading to the damage of expensive medicine because of manual operation reason, stop to spray repeatedly or spray the condition that the overlay area lacked simultaneously.
The invention provides a novel intelligent medicine spraying system, which comprises:
the image module consists of image acquisition equipment and a light source and is used for acquiring a wound image and transmitting the wound image to the main control module;
the distance measuring module is used for measuring the actual distance between the distance measuring equipment and the wound and transmitting the distance data to the main control module;
the main control module consists of an image processing system, a spraying control system and a power control system; the image processing system receives the wound image and the distance data and processes the wound image to obtain wound information; the spraying control system determines spraying parameters according to the wound information; the power control system regulates and controls the on-off and the rotating speed of the motor according to the spraying parameters;
the spraying module consists of a comprehensive pressure control system, a nozzle and a medicine storage device and is regulated and controlled by the main control module; wherein the integrated pressure control system is used for adjusting the type, dosage and pressure of the sprayed medicine; the nozzle is arranged on the sliding rail module and used for spraying target medicines; the drug storage device consists of a plurality of sterile drug storage containers and is controlled by the integrated pressure control system to output the target drug;
the sliding rail module consists of a motor and an XYZ-axis sliding rail; the motor is regulated and controlled by a power control system in the main control module; and a nozzle and distance measuring equipment are mounted at the same height of the Z-axis slide rail.
Preferably, the wound information includes the shape, area and coordinate location of the wound; the spraying parameters comprise the type, dosage, pressure, path and mode of the sprayed medicine; the modes include continuous spraying and intermittent spraying.
Preferably, the image acquisition device is mounted at a fixed height or arranged on a Z-axis slide rail.
Preferably, the integrated pressure control system is a low pressure precision flow control device having an external connector, a piezoelectric actuator, a capillary tube and a drug outlet; wherein the external connector is connected with the medicine storage device; the piezoelectric driver is driven and controlled by the sequence pulses, and the injection quantity of the medicine is quantified by the pulse number; the drug outlet is connected to a nozzle for pumping out the target drug.
Preferably, the nozzle is a detachable nozzle; the medicine outlet is directly sleeved with the nozzle or is connected with the nozzle carried on the Z-axis slide rail through a hose.
Preferably, the spraying module is detachably assembled in the intelligent system; the spray module is manually set with spray parameters such as type, pressure, dose, mode and path of the sprayed drug after being disengaged from the intelligent system.
Preferably, the target drug is a stem cell or a matrix.
The invention has the beneficial effects that: the novel intelligent medicine spraying system provided by the invention adopts modular operation, the whole system comprises a plurality of modules such as an image module, a distance measuring module, a main control module, a spraying module, a sliding rail module and the like, and the content of each module and the collocation among the modules can be adjusted according to actual requirements in the application process; in clinical application requiring accurate spraying dosage and path or rigorous scientific research, manual spraying is not easy to adopt, a highly automated complete set of modules is required to be configured, the shape and the area of a wound are judged by image processing and artificial intelligence, the coordinate position of the wound and the actual distance between the wound and a nozzle are reversely pushed out according to data measured by a distance measuring device, the optimal spraying dosage, mode and path are calculated according to wound information obtained by image data, the spraying height and the spraying range are accurately controlled by utilizing XYZ-axis slide rail movement, and target medicaments are uniformly sprayed on the surface of the wound with high efficiency; in some simple treatment treatments, the spraying module can be detached from the intelligent system independently, and medical staff can manually control the type, pressure, dosage, mode and path of the sprayed medicine according to experience; according to the invention, the medicine spraying system is constructed by adopting a plurality of modules, so that the medicine damage caused by manual operation is effectively avoided, the repeated spraying or the missing condition of the spraying coverage area is avoided, meanwhile, the application prospect is wider, the price is more flexible and the market positioning is more accordant due to the free collocation and selection of a plurality of modes.
Drawings
FIG. 1 is a flow chart of an automated operation of a sprinkler system;
fig. 2 is a flow chart of an automated operation of a master control module in a sprinkler system.
Detailed Description
The present invention is further described in detail below with reference to the attached drawings so that those skilled in the art can implement the invention by referring to the description text.
It will be understood that terms such as "having," "including," and "comprising," as used herein, do not preclude the presence or addition of one or more other elements or groups thereof.
The invention provides a novel intelligent medicine spraying system which comprises an image module, a distance measuring module, a main control module, a spraying module and a sliding rail module, wherein the connection relation of the image module, the distance measuring module, the main control module, the spraying module and the sliding rail module is shown in figure 1.
The image module comprises a light source and a digital camera serving as an image acquisition device, the wound is photographed, an original wound image is transmitted into the main control system to be subjected to related image processing and wound analysis, the number of pixels of the digital camera is 1300 ten thousand, the storage format is non-compression TIF, wound information loss due to compression of the image is reduced, and the camera is arranged at a fixed height so that all wound surfaces can be shot.
The distance measurement module is a laser distance measurement device, install the same high department on the Z axle of slide rail with the nozzle, in order to deal with the wound that fluctuates, like the arm wound, according to the actual distance of wound, the distance of automatic adjustment nozzle and skin, make the wound obtain more even liquid cover, and when the wound is on human trunk or four limbs, because trunk thickness and four limbs thickness are inequality, the scale in original wound image can produce the error message because the real object of being shot and camera distance change, consequently can utilize the laser to measure the actual distance of wound and further release the distance of camera to the wound.
The main control module is responsible for managing other modules, collecting data feedback of each module and processing the data feedback, so that the modules cooperate with each other. The main control module is mainly divided into an image processing system, a spraying control system and a power control system, and meanwhile, a manual operation mode is provided, so that a doctor or a worker directly operates the spraying system to spray stem cells or matrixes according to actual needs. An automatic work flow chart of the whole main control module is shown in fig. 2, and 1) after an image processing system receives an original wound image transmitted by an image module, the image processing system measures data of the distance between a camera and skin by combining a laser range finder, calculates a picture scale, calibrates coordinate parameters of a wound, processes the wound image, filters noise and interference information in a picture, extracts a wound boundary and wound characteristics, and calculates the area and shape of the wound; 2) the spraying control system obtains accurate information of the wound according to the calculation, intelligently plans a spraying path according to an irregular wound shape, controls the sliding rail module to cover all wound areas by the minimum spraying path, avoids the occurrence of repeated spraying or missing of the spraying coverage area, simultaneously synthesizes wound information values obtained after the processing of the wound image after inputting the values of the liquid medicine amount, the type, the density and the like, calculates the required spraying dosage by the system, and the calculation structure is reflected on a display interface, so that a user can further adjust according to the actual condition; 3) the power control system commands the power controller of the slide rail module to control the motor according to the spraying data planned by the spraying control system, so that the mechanical slide block can wake up to move according to a set value. The main control module can also control the hydraulic pressure change of the comprehensive pressure control system in the whole spraying process, so that the medicine is not damaged by excessive pressure, and in order to meet the function of multi-path mixed spraying, an automatic multi-path spraying mode can be provided to meet different requirements of users, such as continuous spraying, for example, the stem cells are sprayed firstly and then the matrix is sprayed; or intermittently sprayed, for example, by spraying stem cells at one spot followed by spraying the substrate, and then moving to the next spot to repeat the above procedure.
The spraying module consists of a comprehensive pressure control system, a nozzle and a liquid storage device. The comprehensive pressure control system is a core module of the whole intelligent medicine spraying equipment, is preferably in a spray pump gun shape, is used for being used independently after being separated from the system, has the main functions of controlling pressure intensity, adjusting spraying dosage and switching spraying liquid, can be accurately controlled to the liquid volume variation with the minimum volume of 50 mu L per second and the maximum volume of more than 1mL, can stably suck and pump out the medicine under certain pressure, and has good liquid medicine output stability; the spray nozzle is mainly responsible for spraying the target medicine liquid, when the intelligent medicine spraying is applied, the spray nozzle is hung on a Z axis of the sliding rail module, the comprehensive pressure control system provides hydraulic pressure to convey the target medicine to the spray nozzle through a hose, and the spray flow is mainly determined by pressure, the size of the spray nozzle, a flow coefficient and a flow velocity coefficient; when the spraying module is detached independently for manual operation setting, the nozzle is sleeved on the medicine outlet of the comprehensive pressure control system, so that manual operation is facilitated. In practical application, the size and the shape of the nozzle can be adjusted for different medicament suspension densities, wound sizes and the like to determine the unit time area of spraying and the spraying speed, meanwhile, the nozzle is of a replaceable structure, the nozzle can be replaced quickly to meet different types of application requirements, and each type of nozzle corresponds to different pressure modes to ensure that the spraying pressure meets the requirements; the medicine storage device adopts a plurality of closed aseptically designed containers, respectively contains different medicines, such as stem cell liquid or matrix liquid, and outputs target medicines under the control of the comprehensive pressure control system.
The slide rail module comprises a motor and an XYZ-axis three-axis movable slide rail, the length of the slide rail can be upgraded and lengthened as required, the slide rail module is controlled by the main control module, the spraying path and the spraying area are accurately controlled through mechanical movement according to calculated spraying parameters, the intelligent system in the scheme can automatically spray the whole human body area within a specified time, drug failure caused by overlong time is avoided, and the intelligent system has good stability and accuracy.
While embodiments of the invention have been described above, it is not limited to the applications set forth in the description and the embodiments, which are fully applicable in various fields of endeavor to which the invention pertains, and further modifications may readily be made by those skilled in the art, it being understood that the invention is not limited to the details shown and described herein without departing from the general concept defined by the appended claims and their equivalents.
Claims (7)
1. A novel intelligent drug spraying system, comprising:
the image module consists of image acquisition equipment and a light source and is used for acquiring a wound image and transmitting the wound image to the main control module;
the distance measuring module is used for measuring the actual distance between the distance measuring equipment and the wound and transmitting the distance data to the main control module;
the main control module consists of an image processing system, a spraying control system and a power control system; the image processing system receives the wound image and the distance data, calculates a picture scale, calibrates the coordinate parameters of the wound, processes the wound image, filters noise and interference signals, extracts the wound boundary and the wound characteristics, and calculates the wound area and shape; the spraying control system determines spraying parameters according to the wound information; the power control system regulates and controls the on-off and the rotating speed of the motor according to the spraying parameters;
the spraying module consists of a comprehensive pressure control system, a nozzle and a medicine storage device and is regulated and controlled by the main control module; wherein the integrated pressure control system is used for adjusting the type, dosage and pressure of the sprayed medicine; the nozzle is arranged on the sliding rail module and used for spraying target medicines; the drug storage device consists of a plurality of sterile drug storage containers and is controlled by the integrated pressure control system to output the target drug;
the sliding rail module consists of a motor and an XYZ-axis sliding rail; the motor is regulated and controlled by a power control system in the main control module; and a nozzle and distance measuring equipment are mounted at the same height of the Z-axis slide rail.
2. The spraying system of claim 1, wherein the spray parameters include a type, dose, pressure, path, and mode of spraying the medicament; the modes include continuous spraying and intermittent spraying.
3. The spraying system of claim 1, wherein the image capture device is mounted at a fixed height or disposed on a Z-axis slide.
4. The spray system of claim 1 wherein said integrated pressure control system is a low pressure precision flow control device having an external connector, a piezoelectric actuator, a capillary tube and a drug outlet; wherein the external connector is connected with the medicine storage device; the piezoelectric driver is driven and controlled by the sequence pulses, and the injection quantity of the medicine is quantified by the pulse number; the drug outlet is connected to a nozzle for pumping out the target drug.
5. The spraying system of claim 4 wherein said nozzle is a removable nozzle; the medicine outlet is directly sleeved with the nozzle or is connected with the nozzle carried on the Z-axis slide rail through a hose.
6. The spraying system of claim 1, wherein said spraying module is removably mounted in an intelligent system; the spraying module is manually set spraying parameters after being separated from the intelligent system.
7. The spraying system of claim 1, wherein the target drug is a stem cell or a matrix.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810462736.9A CN108853702B (en) | 2018-05-15 | 2018-05-15 | Novel intelligent medicine sprinkling system |
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| CN201810462736.9A CN108853702B (en) | 2018-05-15 | 2018-05-15 | Novel intelligent medicine sprinkling system |
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| CN108853702A CN108853702A (en) | 2018-11-23 |
| CN108853702B true CN108853702B (en) | 2021-02-26 |
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| CN108624581A (en) * | 2018-05-15 | 2018-10-09 | 中国科学院苏州生物医学工程技术研究所 | A kind of microballoon and brainpower insufflation system of mescenchymal stem cell materials for binding biological |
| CN109847155B (en) * | 2019-01-21 | 2021-04-09 | 陶淑娟 | Adaptive disease processing platform |
| CN110051914B (en) * | 2019-04-29 | 2021-02-23 | 青岛大学附属医院 | Automatic medicine device that spouts of department of anesthesia |
| CN111420255A (en) * | 2020-03-19 | 2020-07-17 | 德阳市人民医院 | Medicine feeding device for gynecological nursing for avoiding secondary infection of wound |
| CN111358618A (en) * | 2020-03-20 | 2020-07-03 | 上海交通大学医学院附属新华医院 | Intelligent eye drop atomizer |
| CN112089422A (en) * | 2020-07-02 | 2020-12-18 | 王兆英 | Self-adaptive medical system and method based on wound area analysis |
| CN112245789A (en) * | 2020-11-04 | 2021-01-22 | 江苏师范大学 | Body surface scald nursing instrument |
| CN114984431B (en) * | 2022-06-08 | 2024-03-15 | 黑龙江中医药大学 | Traditional chinese medical science dermatological medicine smearing device |
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