CN108765509B - Rapid image reconstruction method for linear imaging system - Google Patents
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Abstract
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技术领域technical field
本发明属于生物医学成像、无损检测、图像重建等技术领域,特别是涉及一种用于线性成像系统的快速图像重建方法。The invention belongs to the technical fields of biomedical imaging, non-destructive testing, image reconstruction and the like, in particular to a fast image reconstruction method for a linear imaging system.
背景技术Background technique
图像信息是信息工程学科领域中信息量包含最大、内容最丰富的一个分支,现代成像系统综合光学、电子、计算机、机械等技术将客观世界中的信息以各种方式转变成图像信息,极大丰富了人类的视觉世界,已在医学诊断、无损检测、探测、侦查等众多领域获得了广泛的应用。目前,现代成像系统新技术发展的特点主要体现在数字化、多功能化、多维化及信息化等方面的综合应用上,成像的功能与性能很大程度上依赖于所使用的成像算法。因此,成像算法是成像系统的关键,也是成像技术研究的热点。Image information is a branch with the largest amount of information and the most abundant content in the field of information engineering. The modern imaging system integrates optics, electronics, computers, machinery and other technologies to transform the information in the objective world into image information in various ways. It has enriched the human visual world and has been widely used in many fields such as medical diagnosis, non-destructive testing, detection, and reconnaissance. At present, the characteristics of the development of new technologies in modern imaging systems are mainly reflected in the comprehensive application of digitization, multi-functionalization, multi-dimensionalization and informatization. The functions and performance of imaging largely depend on the imaging algorithms used. Therefore, the imaging algorithm is the key to the imaging system, and it is also the hotspot of imaging technology research.
对于许多线性成像系统,在数学上常可以用一个线性模型来建模,其中包含对大规模线性方程组的求解,可采用的成像算法有解析法与迭代求解方法。以计算机断层扫描(CT)成像为例,现阶段的CT成像系统多采用滤波反投影法(FBP),其优点是计算量小,重建速度快,当投影数据完备时能获得良好的重建图像质量。但在实际检测中,由于诸多客观原因,经常出现难以检测完整投影数据的情况。当投影数据不充分时,FBP算法重建的图像质量严重下降,难以满足实际应用需求。For many linear imaging systems, a linear model can often be used to model mathematically, which includes the solution of large-scale linear equations. The imaging algorithms that can be used include analytical and iterative solutions. Taking computed tomography (CT) imaging as an example, the current CT imaging systems mostly use the filtered back projection (FBP) method, which has the advantages of small calculation amount, fast reconstruction speed, and good reconstructed image quality when the projection data is complete. . However, in actual detection, due to many objective reasons, it is often difficult to detect complete projection data. When the projection data is insufficient, the quality of the image reconstructed by the FBP algorithm is seriously degraded, and it is difficult to meet the needs of practical applications.
与FBP为代表的解析法不同,代数重建技术(ART)在成像一开始阶段就将图像重建问题转化为求解(大规模)线性方程组问题,可以结合先验信息,根据不同要求选取不同的目标函数进行迭代求解,在稀疏或不完备投影数据条件下时仍可重建高质量图像。但代数重建法的最大缺点是计算量大,重建速度较慢,算法的时间成本是阻碍其推广的重要因素。Different from the analytical method represented by FBP, Algebraic Reconstruction Technology (ART) transforms the image reconstruction problem into the problem of solving a (large-scale) linear equation system at the beginning of imaging, which can be combined with prior information to select different targets according to different requirements. The function is iteratively solved, and high-quality images can still be reconstructed under the condition of sparse or incomplete projection data. But the biggest disadvantage of the algebraic reconstruction method is the large amount of calculation and the slow reconstruction speed. The time cost of the algorithm is an important factor hindering its popularization.
近年来,计算机技术的进步为图像重建创造了新的硬件环境,代数重建方法的技术优势更加凸显。为了使代数重建算法普遍应用于实际成像系统,急需研究开发简单高效的快速重建算法,结合图像先验信息,在不完备投影数据情况下实现快速精确成像。In recent years, the advancement of computer technology has created a new hardware environment for image reconstruction, and the technical advantages of algebraic reconstruction methods have become more prominent. In order to make the algebraic reconstruction algorithm widely used in the actual imaging system, it is urgent to research and develop a simple and efficient fast reconstruction algorithm, combining with the prior information of the image, to achieve fast and accurate imaging in the case of incomplete projection data.
作为最接近的现有技术,本发明人已申请的专利“一种应用于CT成像的快速代数重建方法”(申请号201510988996.6)公开了在传统代数重建法基础上,任意选择部分超平面,在这些超平面上对由传统代数重建法得到的投影解向量进行进一步的加速调整操作,使调整更新后的解向量在原投影解向量与前一次迭代该超平面上对应向量的连线上最优。该方法明显提高了算法收敛速度,获得了有益效果,但在直接应用于不完备投影数据的图像重建时仍存在一些不足:算法中的加速调整操作依赖于当前向量与前一次迭代同一超平面上向量的关系,若在每次迭代得到的当前向量基础上再结合先验信息执行先验信息优化操作,则由于先验信息优化操作而增加的对向量的扰动或变化将破坏这种依赖关系,导致算法后续的迭代计算失效。因此,已申请的专利(申请号201510988996.6)所公开的方法在与其它先验信息优化算子相结合时会受到一定的限制,需要做专门的处理,这不利于该算法灵活地结合先验信息实现不完备投影数据情况下的快速图像重建。As the closest prior art, the patent "A Fast Algebraic Reconstruction Method Applied to CT Imaging" (application number 201510988996.6) that the inventor has applied for discloses that on the basis of the traditional algebraic reconstruction method, some hyperplanes are arbitrarily selected, On these hyperplanes, the projection solution vector obtained by the traditional algebraic reconstruction method is further accelerated and adjusted, so that the adjusted and updated solution vector is optimal on the connecting line between the original projection solution vector and the corresponding vector on the hyperplane in the previous iteration. This method significantly improves the convergence speed of the algorithm and obtains beneficial effects, but there are still some shortcomings when it is directly applied to image reconstruction of incomplete projection data: the accelerated adjustment operation in the algorithm depends on the current vector on the same hyperplane as the previous iteration. If the prior information optimization operation is performed on the basis of the current vector obtained by each iteration and the prior information is combined, the disturbance or change to the vector due to the prior information optimization operation will destroy this dependency. The subsequent iterative calculation of the algorithm fails. Therefore, the method disclosed in the applied patent (application number 201510988996.6) is subject to certain limitations when combined with other prior information optimization operators, and requires special processing, which is not conducive to the algorithm flexibly combining prior information Enables fast image reconstruction with incomplete projection data.
发明内容SUMMARY OF THE INVENTION
为了解决上述问题,本发明提供一种用于线性成像系统的快速图像重建方法,该方法在一次迭代内部直接进行多次加速调整与先验信息优化操作,只引入一个辅助向量与辅助标量,几乎不额外增加算法存储量与计算量,在迭代过程不依赖于前次迭代变量,易于直接结合先验信息实现不完备数据情况下的快速图像重建,该方法引入松弛参数并推导了辅助标量更新与加速调整操作的相应公式,适用于噪声环境。本发明采用的技术方案是:In order to solve the above problems, the present invention provides a fast image reconstruction method for a linear imaging system. The method directly performs multiple acceleration adjustments and prior information optimization operations within one iteration, and only introduces an auxiliary vector and auxiliary scalar, which is almost It does not increase the storage and calculation amount of the algorithm, the iteration process does not depend on the previous iteration variables, and it is easy to directly combine the prior information to achieve fast image reconstruction in the case of incomplete data. The method introduces relaxation parameters and derives the auxiliary scalar update and Corresponding formula for speeding up adjustment operations, suitable for noisy environments. The technical scheme adopted in the present invention is:
一种用于线性成像系统的快速图像重建方法,首先建立线性成像系统的离散化数学模型及先验信息数学模型,将线性成像系统的成像问题转化为大规模线性方程组求解与先验信息优化问题,然后结合加速调整算子与先验信息优化算子迭代求解大规模线性方程组,优化先验信息,在稀疏或不完备投影数据条件下重建高质量图像;所求解的大规模线性方程组表示为Ax=b,其中,x为待求图像的向量表示,为N×1向量,由对二维或三维图像按一维重新排列得到,A是M×N系统矩阵,用向量ai表示矩阵A第i行向量的转置,b为M×1测量数据向量,用bi表示向量b的第i个元素;其求解过程包括以下步骤:A fast image reconstruction method for linear imaging systems. First, a discrete mathematical model and a priori information mathematical model of the linear imaging system are established, and the imaging problem of the linear imaging system is transformed into a large-scale linear equation system solution and prior information optimization. Then combine the accelerated adjustment operator and the prior information optimization operator to iteratively solve the large-scale linear equation system, optimize the prior information, and reconstruct high-quality images under the condition of sparse or incomplete projection data; the solved large-scale linear equation system It is expressed as Ax=b, where x is the vector representation of the image to be obtained, which is an N×1 vector, obtained by rearranging a two-dimensional or three-dimensional image in one dimension, A is an M×N system matrix, represented by a vector a i The transposition of the vector in the ith row of matrix A, b is the M×1 measurement data vector, and the ith element of vector b is represented by b i ; the solution process includes the following steps:
步骤一:初始化:设定初始解向量x0,松弛参数ρ、γ,及每次循环迭代内部进行加速调整与先验信息优化操作的个数T,并令迭代数k=0,当前向量(即当前估计解向量)x=x0,辅助标量d=0,辅助向量z=x0;Step 1: Initialization: Set the initial solution vector x 0 , relaxation parameters ρ, γ, and the number T of acceleration adjustment and prior information optimization operations performed inside each loop iteration, and set the number of iterations k=0, the current vector ( That is, the current estimated solution vector) x=x 0 , the auxiliary scalar d=0, and the auxiliary vector z=x 0 ;
步骤二:迭代过程:对第k次迭代重复以下步骤直到满足收敛条件:Step 2: Iterative process: Repeat the following steps for the k-th iteration until the convergence conditions are met:
(2.1)设定超平面投影顺序,用sl表示第l个投影超平面的序号,其中,l=1,2,...M, M表示超平面的个数,并且令t=1,t表示迭代内部第t次进行加速调整与先验信息优化操作;(2.1) Set the hyperplane projection order, and use s l to denote the serial number of the l-th projection hyperplane, where l=1, 2,...M, M denotes the number of hyperplanes, and let t=1, t represents the t-th time to perform acceleration adjustment and prior information optimization operations within the iteration;
(2.2)针对每一个超平面i=sl,l=1,2,...M,对当前向量x依次执行如下操作进行更新:(2.2) For each hyperplane i=s l , l=1, 2,...M, perform the following operations to update the current vector x in sequence:
(2.2.1)对当前向量x执行向超平面i的投影操作,更新当前向量x与对应辅助标量d:(2.2.1) Perform the projection operation on the current vector x to the hyperplane i, and update the current vector x and the corresponding auxiliary scalar d:
[x,d]←proj(x,d,ρ,ai,bi)[x,d]←proj(x,d,ρ,a i ,b i )
其中,[x',d']=proj(x,d,ρ,ai,bi),表示投影与辅助标量d更新操作,“←”为赋值符号;Among them, [x', d']=proj(x, d, ρ, a i , b i ), represents the update operation of projection and auxiliary scalar d, and "←" is the assignment symbol;
(2.2.2)如果则对当前向量x进一步执行加速调整与先验信息优化操作,更新当前向量x,及对应的辅助向量z与辅助标量d:(2.2.2) If Then further perform acceleration adjustment and prior information optimization operations on the current vector x, update the current vector x, and the corresponding auxiliary vector z and auxiliary scalar d:
[x,z,d]←lineAcc(x,z,d,γ)[x,z,d]←lineAcc(x,z,d,γ)
t←t+1;t←t+1;
上式中,表示向上取整;[x',z',d']=lineAcc(x,z,d,γ)表示加速调整与先验信息优化操作;In the above formula, Represents rounding up; [x', z', d']=lineAcc(x, z, d, γ) represents accelerated adjustment and prior information optimization operations;
(2.3)k←k+1。(2.3) k←k+1.
进一步的是,所述步骤一中,松弛参数ρ、γ的取值范围为(0,1],加速调整与先验信息优化操作个数T的取值范围为1≤T≤M。Further, in the first step, the value range of the relaxation parameters ρ and γ is (0, 1], and the value range of the number T of acceleration adjustment and prior information optimization operations is 1≤T≤M.
进一步的是,所述步骤(2.1)中采用固定投影顺序或随机投影顺序设定超平面投影顺序。Further, in the step (2.1), a fixed projection order or a random projection order is used to set the hyperplane projection order.
进一步的是,所述步骤(2.1)中若采用固定投影顺序设定超平面投影顺序,每次迭代第 l(l=1,2,...M)个投影超平面的序号i=sl的值是固定的,则每次迭代步骤(2.2.2)中的加速调整与先验信息优化操作针对的是相同的超平面序号;反之,若采用随机投影顺序设定超平面投影顺序,每次迭代第l个投影超平面的序号i=sl是随机的,则每次迭代步骤(2.2.2)中的加速调整与先验信息优化操作针对的是不同的超平面序号。Further, in the step (2.1), if a fixed projection sequence is used to set the hyperplane projection sequence, the sequence number i=s l of the lth (l=1, 2,...M) projection hyperplane in each iteration is fixed, the acceleration adjustment and prior information optimization operation in each iteration step (2.2.2) are aimed at the same hyperplane number; otherwise, if the random projection order is used to set the hyperplane projection order, each The sequence number i=s l of the l-th projection hyperplane in the second iteration is random, and the acceleration adjustment and prior information optimization operations in each iteration step (2.2.2) are aimed at different hyperplane numbers.
进一步的是,所述步骤(2.2.1)中的投影操作[x',d']=proj(x,d,ρ,ai,bi)定义如下:Further, the projection operation [x', d']=proj(x, d, ρ, a i , b i ) in the step (2.2.1) is defined as follows:
[x',d']=proj(x,d,ρ,ai,bi)[x',d']=proj(x,d,ρ,a i ,b i )
λ=bi-<ai,x> (1)λ=b i -<a i ,x> (1)
当ρ=1时,投影操作[x',d']=proj(x,d,λ,ai,bi)的输出x′是当前向量x到超平面i的投影点。执行完投影操作后,满足:||x*-x||2-||x*-x'||2=d-d',其中x*是方程组的真实解,即所有超平面的交集。When ρ=1, the output x' of the projection operation [x', d']=proj(x, d, λ, a i , b i ) is the projection point of the current vector x to the hyperplane i. After performing the projection operation, satisfy: ||x * -x|| 2 -||x * -x'|| 2 =d-d', where x * is the true solution of the system of equations, that is, the intersection of all hyperplanes .
进一步的是,所述步骤(2.2.2)中的加速调整与先验信息优化操作[x',z',d']=lineAcc(x,z,d,γ)定义如下:Further, the acceleration adjustment and prior information optimization operation [x', z', d']=lineAcc(x, z, d, γ) in the step (2.2.2) is defined as follows:
[x',z',d']=lineAcc(x,z,d,γ)[x',z',d']=lineAcc(x,z,d,γ)
u=x-z (4)u=x-z (4)
x″=x+γβu (6)x″=x+γβu (6)
x'=Sup(x″) (7)x'=Sup(x″) (7)
z'=x' (8)z'=x' (8)
d'=0 (9)d'=0 (9)
加速调整与先验信息优化操作[x',z',d']=lineAcc(x,z,d,γ)的式(4)、(5)、(6)执行加速调整操作,当||x*-z||2-||x*-x||2=0-d(该式在算法迭代过程执行加速调整与先验信息优化操作前一直满足)且γ=1时,式(6)得到的x″是向量x与对应辅助向量z的连线上距方程组真实解 x*最近的点;当0<γ≤1时,x″比更新前的向量x离方程组真实解x*的距离更近。其中,x*是所有超平面的交集,即对于i=1,2,…,M,有:<ai,x*>=bi。[x',z',d']=lineAcc(x,z,d,γ)的式(7)执行先验信息优化操作,x'=Sup(x″)返回的x′比x″与图像的先验信息更接近。图像的先验信息有多种表示方式,很多时候会以某种数学变换来描述。比如,一种有效且广泛使用的数学描述方式是图像的全变分(Total variance,TV)范数,一般图像的TV范数是比较小的。当采用TV范数描述先验信息时,本发明方法中的先验信息优化操作x'=Sup(x″)是减小图像的TV范数,即返回的x′比x″具有更小的图像TV范数。[x',z',d']=lineAcc(x,z,d,γ)的式(8)、 (9)分别更新了辅助向量z与辅助标量d。执行加速调整与先验信息优化操作 [x',z',d']=lineAcc(x,z,d,γ)后,总体说来,更新后的向量x′比更新前的向量x具有更小的测量误差,与图像的先验信息更为接近(如TV范数更小)。Accelerated adjustment and prior information optimization operation [x', z', d']=lineAcc(x, z, d, γ) Formulas (4), (5), (6) perform the accelerated adjustment operation, when || x * -z|| 2 -||x * -x|| 2 =0-d (this formula is always satisfied before the acceleration adjustment and prior information optimization operation is performed in the iterative process of the algorithm) and when γ=1, formula (6 ) obtained x″ is the closest point to the real solution x * of the system of equations on the connection line between the vector x and the corresponding auxiliary vector z; when 0<γ≤1, x″ is closer than the vector x before the update to the real solution x of the system of equations * is closer. where x * is the intersection of all hyperplanes, ie for i=1,2,...,M, there are: <a i ,x*> =b i . [x', z', d']=lineAcc(x, z, d, γ) formula (7) performs prior information optimization operation, x'=Sup(x") returns x' ratio x" and the image The prior information is closer. The prior information of the image has many representations, and is often described by some mathematical transformation. For example, an effective and widely used mathematical description method is the Total Variation (TV) norm of the image, and the TV norm of the general image is relatively small. When the TV norm is used to describe the prior information, the prior information optimization operation x'=Sup(x") in the method of the present invention is to reduce the TV norm of the image, that is, the returned x' has a smaller value than x" Image TV norm. Formulas (8) and (9) of [x', z', d']=lineAcc(x, z, d, γ) update the auxiliary vector z and the auxiliary scalar d, respectively. After performing the accelerated adjustment and prior information optimization operation [x', z', d'] = lineAcc(x, z, d, γ), in general, the updated vector x' has more Small measurement error, which is closer to the prior information of the image (eg, the TV norm is smaller).
本发明的理论分析为:The theoretical analysis of the present invention is:
代数重建技术的基本思想是:将各方程看作N维空间的一个超平面,从初始解向量x0出发,在每次迭代,按照一定的投影顺序,依次向各超平面进行一轮循环投影操作,逐步逼近方程组的真实解。以顺序投影(依次投影的超平面序号为1,2,…,M)为例,在每次迭代,由当前估计解向量(简称当前向量)x出发,按超平面投影顺序i=1,2,…,M,依次执行如下操作,不断更新估计解向量x:The basic idea of the algebraic reconstruction technique is to regard each equation as a hyperplane in an N-dimensional space, starting from the initial solution vector x 0 , and in each iteration, according to a certain projection sequence, perform a round of cyclic projection to each hyperplane in turn. operation, step-by-step approximation to the true solution of the system of equations. Taking sequential projection (the hyperplane numbers of the sequential projection are 1, 2, ..., M) as an example, in each iteration, starting from the current estimated solution vector (referred to as the current vector) x, according to the hyperplane projection order i=1, 2 ,...,M, perform the following operations in sequence to continuously update the estimated solution vector x:
λ←bi-<ai,x> (10)λ←b i -<a i ,x> (10)
上式中的<·>为内积符号,“←”为赋值符号。式(11)描述了投影操作,式子右边的向量 x为执行投影操作前的向量,式子左边的向量x为执行投影操作后更新的向量。ρ为ART算法的松弛参数,应用于噪声环境,取值范围一般在(0,1]之间。当ρ=1时,式(10)、(11)将当前向量x投影到序号为i的超平面(简称超平面i)上。<·> in the above formula is the inner product symbol, and "←" is the assignment symbol. Equation (11) describes the projection operation, the vector x on the right side of the expression is the vector before the projection operation is performed, and the vector x on the left side of the expression is the vector updated after the projection operation is performed. ρ is the relaxation parameter of the ART algorithm, which is applied to the noise environment. The value range is generally between (0, 1]. When ρ = 1, formulas (10) and (11) project the current vector x to the sequence number i. on the hyperplane (referred to as hyperplane i).
在本发明方法中,若将步骤(2.2.2)的加速调整与先验信息优化操作去掉,或将进行加速调整与先验信息优化操作的个数T设为0,则本发明方法退化为传统的代数重建法。加上步骤(2.2.2)的加速调整与先验信息优化操作后,提高了算法速度,同时在稀疏或不完备投影数据条件下重建高质量图像。In the method of the present invention, if the accelerated adjustment and prior information optimization operations in step (2.2.2) are removed, or the number T of the accelerated adjustment and prior information optimization operations is set to 0, the method of the present invention degenerates into Traditional algebraic reconstruction method. After adding the accelerated adjustment and prior information optimization operations of step (2.2.2), the algorithm speed is improved, and high-quality images are reconstructed under the condition of sparse or incomplete projection data.
首先说明在步骤(2.2.1)中,对当前向量x执行向超平面i的投影操作[x',d']=proj(x,d,ρ,ai,bi)后,有:First, in step (2.2.1), after performing the projection operation [x', d']=proj(x, d, ρ, a i , b i ) on the current vector x to the hyperplane i, there are:
||x*-x||2-||x*-x'||2=d-d' (12)||x * -x|| 2 -||x * -x'|| 2 =dd' (12)
证明如下:The proof is as follows:
当式(2)中的松弛参数ρ=1时,由式(2)得到的向量x′(表示为xp)为当前向量x在超平面i的投影点:When the relaxation parameter ρ=1 in the formula (2), the vector x′ (represented as x p ) obtained by the formula (2) is the projection point of the current vector x on the hyperplane i:
即,xp满足:That is, x p satisfies:
<x-xp,x*-xp>=0 (14)<xx p ,x * -x p >=0 (14)
对应的有:Corresponding to:
||x*-x||2=||x*-xp||2+||x-xp||2 (15)||x * -x|| 2 = ||x * -x p || 2 +||xx p || 2 (15)
||x*-x'||2=||x*-xp||2+||x'-xp||2 (16)||x * -x'|| 2 = ||x * -x p || 2 +||x'-x p || 2 (16)
由式(2)与式(13)可得:From formula (2) and formula (13), we can get:
结合式(15),(16),(17),(18)可得:Combining equations (15), (16), (17), (18), we can get:
由式(19)与式(3)可得:From formula (19) and formula (3), we can get:
||x*-x||2-||x*-x'||2=d-d'||x * -x|| 2 -||x * -x'|| 2 =d-d'
证明完毕。The proof is complete.
在算法迭代过程中,向量x与辅助标量d对应,辅助向量z与辅助标量0相对应。结合上述性质,可知在步骤(2.2.2)中执行加速调整与先验信息优化操作前满足下述条件:In the iterative process of the algorithm, the vector x corresponds to the auxiliary scalar d, and the auxiliary vector z corresponds to the auxiliary scalar 0. Combining the above properties, it can be seen that the following conditions are met before the accelerated adjustment and prior information optimization operations are performed in step (2.2.2):
||x*-z||2-||x*-x||2=0-d (20)||x * -z|| 2 -||x * -x|| 2 = 0-d (20)
下面说明,若γ=1,步骤(2.2.2)中执行加速调整与先验信息优化操作[x',z',d']=lineAcc(x,z,d,γ)的式(6)后,返回的x″是向量x与对应辅助向量z的连线上距方程组真实解x*最近的点,即满足In the following, if γ=1, the acceleration adjustment and prior information optimization operation [x', z', d']=lineAcc(x, z, d, γ) is performed in step (2.2.2) in formula (6) After that, the returned x″ is the closest point to the real solution x * of the equation system on the connection line between the vector x and the corresponding auxiliary vector z, that is, it satisfies
<u,x*-x″>=0 (21)<u,x * -x">=0 (21)
上式中的u,x″分别由式(4),(6)定义(令γ=1),即当γ=1时,若由更新x的式(6)返回的 x″是向量x与对应辅助向量z的连线上距方程组真实解x*最近的点,则式(6)中的β由式(5) 定义。u, x″ in the above formula are defined by formulas (4) and (6) respectively (let γ=1), that is, when γ=1, if the x″ returned by formula (6) for updating x is the vector x and Corresponding to the point on the connection line of the auxiliary vector z that is closest to the real solution x * of the equation system, then β in equation (6) is defined by equation (5).
证明如下:The proof is as follows:
结合式(21),(4),(6)可得:Combining formulas (21), (4), (6), we can get:
||x*-x||2=||x*-x″||2+β2||u||2 (22)||x * -x|| 2 =||x * -x″|| 2 +β 2 ||u|| 2 (22)
||x*-z||2=||x*-x″||2+(1+β)2||u||2 (23)||x * -z|| 2 =||x * -x″|| 2 +(1+β) 2 ||u|| 2 (23)
由式(22),(23),可知:From equations (22), (23), we can know that:
||x*-z||2-||x*-x||2=(2β+1)||u||2 (24)||x * -z|| 2 -||x * -x|| 2 =(2β+1)||u|| 2 (24)
结合式(20),(24),可知:Combining formulas (20) and (24), it can be known that:
即为式(5)的计算表达式。It is the calculation expression of formula (5).
证明完毕。The proof is complete.
考虑到噪声原因,式(2)与式(6)中引入了松弛参数ρ,γ。当0<γ≤1时,由加速调整与先验信息优化操作[x',z',d']=lineAcc(x,z,d,γ)式(6)返回的向量x″比更新前的向量x离方程组真实解x*的距离更近。Considering the reason of noise, relaxation parameters ρ and γ are introduced into equations (2) and (6). When 0<γ≤1, the vector x″ returned by the acceleration adjustment and prior information optimization operation [x', z', d']=lineAcc(x, z, d, γ) formula (6) is smaller than before the update The vector x of is closer to the true solution x * of the system of equations.
采用本技术方案的有益效果:The beneficial effects of adopting this technical solution:
1.与现有技术(即本发明人前申请专利(申请号201510988996.6)所公开的方法)相比,本发明方法在一次循环迭代内部直接进行多次加速调整与先验信息优化操作,由于迭代过程不依赖于前次迭代变量,更易于直接结合先验信息实现不完备投影情况下的快速图像重建。1. Compared with the prior art (that is, the method disclosed by the inventor's previous patent application (application number 201510988996.6)), the method of the present invention directly performs multiple acceleration adjustments and priori information optimization operations within one loop iteration, due to the iterative process. It does not depend on the previous iteration variables, and it is easier to directly combine the prior information to achieve fast image reconstruction in the case of incomplete projection.
2.与现有技术(即本发明人前申请专利(申请号201510988996.6)所公开的方法)相比,本发明方法对噪声环境适当引入松弛参数并推导了辅助标量更新与加速调整操作的相应公式,扩大了方法的适用范围。2. Compared with the prior art (that is, the method disclosed by the inventor's previous patent application (application number 201510988996.6)), the method of the present invention appropriately introduces relaxation parameters to the noise environment and derives the corresponding formulas for auxiliary scalar update and accelerated adjustment operations, Expanded the scope of application of the method.
3.提高图像重建算法收敛速度:本发明方法与传统代数重建法相比只增加了一个辅助向量z,所增加的额外存储空间完全可以忽略。实际应用中,每次迭代内部加速调整与先验信息优化操作的个数T可以设得很小(如小于10),这样额外增加的计算量同样可以忽略,且仿真结果表明算法的收敛速度却可以显著提高。3. Improve the convergence speed of the image reconstruction algorithm: compared with the traditional algebraic reconstruction method, the method of the present invention only adds an auxiliary vector z, and the additional storage space added can be completely ignored. In practical applications, the number T of the internal acceleration adjustment and prior information optimization operations in each iteration can be set very small (for example, less than 10), so that the additional calculation amount can also be ignored, and the simulation results show that the convergence speed of the algorithm is not can be significantly improved.
4.能够有效扩展成像系统应用:本发明方法可针对不同线性成像系统应用,灵活利用相应先验信息,实现不完备数据条件下的快速图像重建。4. The application of the imaging system can be effectively expanded: the method of the present invention can be applied to different linear imaging systems, flexibly utilize the corresponding prior information, and realize fast image reconstruction under the condition of incomplete data.
附图说明Description of drawings
下面结合附图对本发明作进一步详细说明。The present invention will be further described in detail below in conjunction with the accompanying drawings.
图1为本发明的一种用于线性成像系统的快速图像重建方法流程示意图;1 is a schematic flowchart of a fast image reconstruction method for a linear imaging system according to the present invention;
图2为本发明方法中针对超平面i=sl,对当前向量x执行更新操作的流程示意图;2 is a schematic flowchart of performing an update operation on a current vector x for hyperplane i=s l in the method of the present invention;
图3为本发明方法的一个实施例重建图像与原始图像的比较图;3 is a comparison diagram of a reconstructed image and an original image according to an embodiment of the method of the present invention;
图4为本发明方法的实施例与结合ART与TV范数优化的算法平方向量误差收敛曲线图。FIG. 4 is an embodiment of the method of the present invention and an algorithm square vector error convergence curve diagram combining ART and TV norm optimization.
具体实施方式Detailed ways
为了使本发明的目的、技术方案和优点更加清楚,下面结合附图和具体实施例对本发明作进一步阐述。In order to make the objectives, technical solutions and advantages of the present invention clearer, the present invention will be further described below with reference to the accompanying drawings and specific embodiments.
在本实施例中,参见图1、图2所示,一种用于CT成像系统的快速图像重建方法,首先建立CT成像系统的离散化数学模型及先验信息数学模型,将CT成像问题转化为大规模线性方程组求解与先验信息优化问题,然后结合加速调整算子与先验信息优化算子迭代求解大规模线性方程组,优化先验信息,在稀疏或不完备投影数据条件下重建高质量图像,所求解的大规模线性方程组表示为Ax=b,其中,x为待求图像的向量表示,为N×1向量,由对二维图像按一维重新排列得到,A是M×N系统矩阵,用向量ai表示矩阵A第i行向量的转置,b为M×1测量数据向量,用bi表示向量b的第i个元素;其求解过程包括以下步骤:In this embodiment, as shown in FIG. 1 and FIG. 2, a fast image reconstruction method for CT imaging system is firstly established to establish a discrete mathematical model and a priori information mathematical model of the CT imaging system, and transform the CT imaging problem into Solve large-scale linear equations and prior information optimization problems, then combine accelerated adjustment operators and prior information optimization operators to iteratively solve large-scale linear equations, optimize prior information, and reconstruct under the condition of sparse or incomplete projection data For high-quality images, the large-scale linear equations to be solved are expressed as Ax=b, where x is the vector representation of the image to be solved, which is an N×1 vector, obtained by rearranging the two-dimensional image in one dimension, and A is M ×N system matrix, the vector a i represents the transpose of the ith row vector of matrix A, b is the M×1 measurement data vector, and b i represents the ith element of vector b; the solution process includes the following steps:
步骤一:初始化:设定初始解向量x0,松弛参数ρ、γ,及每次循环迭代内部进行加速调整与先验信息优化操作的个数T,并令迭代数k=0,当前向量x=x0,辅助标量d=0,辅助向量z=x0;Step 1: Initialization: Set the initial solution vector x 0 , relaxation parameters ρ, γ, and the number T of acceleration adjustment and prior information optimization operations performed in each loop iteration, and set the number of iterations k=0, the current vector x =x 0 , auxiliary scalar d=0, auxiliary vector z=x 0 ;
所述步骤一中,松弛参数ρ、γ的取值范围为(0,1],加速调整与先验信息优化操作个数 T的取值范围为1≤T≤M。In the first step, the value range of the relaxation parameters ρ and γ is (0, 1], and the value range of the number T of acceleration adjustment and prior information optimization operations is 1≤T≤M.
步骤二:迭代过程:对第k次迭代重复以下步骤直到满足收敛条件:Step 2: Iterative process: Repeat the following steps for the k-th iteration until the convergence conditions are met:
(2.1)设定超平面投影顺序,用sl表示第l个投影超平面的序号,其中,l=1,2,...M, M表示超平面的个数,并且令t=1,t用于表示迭代内部第t次进行加速调整与先验信息优化操作;(2.1) Set the hyperplane projection order, and use s l to denote the serial number of the l-th projection hyperplane, where l=1, 2,...M, M denotes the number of hyperplanes, and let t=1, t is used to represent the t-th time to perform accelerated adjustment and prior information optimization operations within the iteration;
所述步骤(2.1)中采用固定投影顺序或随机投影顺序设定超平面投影顺序。In the step (2.1), a fixed projection sequence or a random projection sequence is used to set the hyperplane projection sequence.
(2.2)针对每一个超平面i=sl,l=1,2,...M,对当前向量x依次执行如下操作进行更新:(2.2) For each hyperplane i=s l , l=1, 2,...M, perform the following operations to update the current vector x in sequence:
(2.2.1)对当前向量x执行向超平面i的投影操作,更新当前向量x与对应辅助标量d:(2.2.1) Perform the projection operation on the current vector x to the hyperplane i, and update the current vector x and the corresponding auxiliary scalar d:
[x,d]←proj(x,d,ρ,ai,bi)[x,d]←proj(x,d,ρ,a i ,b i )
其中,[x',d']=proj(x,d,ρ,ai,bi),表示投影与辅助标量d更新操作,“←”为赋值符号;Among them, [x', d']=proj(x, d, ρ, a i , b i ), represents the update operation of projection and auxiliary scalar d, and "←" is the assignment symbol;
所述步骤(2.2.1)中的投影操作[x',d']=proj(x,d,ρ,ai,bi)定义如下:The projection operation [x', d']=proj(x, d, ρ, a i , b i ) in the step (2.2.1) is defined as follows:
[x',d']=proj(x,d,ρ,ai,bi)[x',d']=proj(x,d,ρ,a i ,b i )
λ=bi-<ai,x> (1)λ=b i -<a i ,x> (1)
当ρ=1时,投影操作[x',d']=proj(x,d,λ,ai,bi)的输出x′是当前向量x到超平面i的投影点。执行完投影操作后,满足:||x*-x||2-||x*-x'||2=d-d',其中x*是方程组的真实解。When ρ=1, the output x' of the projection operation [x', d']=proj(x, d, λ, a i , b i ) is the projection point of the current vector x to the hyperplane i. After performing the projection operation, satisfy: ||x * -x|| 2 -||x * -x'|| 2 =d-d', where x * is the true solution of the system of equations.
(2.2.2)如果则对当前向量x进一步执行加速调整与先验信息优化操作,更新当前向量x,及对应的辅助向量z与辅助标量d:(2.2.2) If Then further perform acceleration adjustment and prior information optimization operations on the current vector x, update the current vector x, and the corresponding auxiliary vector z and auxiliary scalar d:
[x,z,d]←lineAcc(x,z,d,γ)[x,z,d]←lineAcc(x,z,d,γ)
t←t+1;t←t+1;
上式中,表示向上取整;[x',z',d']=lineAcc(x,z,d,γ)表示加速调整与先验信息优化操作;In the above formula, Represents rounding up; [x', z', d']=lineAcc(x, z, d, γ) represents accelerated adjustment and prior information optimization operations;
所述步骤(2.2.2)中的加速调整与先验信息优化操作[x',z',d']=lineAcc(x,z,d,γ)定义如下:The acceleration adjustment and prior information optimization operation [x', z', d']=lineAcc(x, z, d, γ) in the step (2.2.2) is defined as follows:
[x',z',d']=lineAcc(x,z,d,γ)[x',z',d']=lineAcc(x,z,d,γ)
u=x-z (4)u=x-z (4)
x″=x+γβu (6)x″=x+γβu (6)
x'=Sup(x″) (7)x'=Sup(x″) (7)
z'=x' (8)z'=x' (8)
d'=0 (9)d'=0 (9)
加速调整与先验信息优化操作[x',z',d']=lineAcc(x,z,d,γ)的式(4)、(5)、(6)执行加速调整操作,当||x*-z||2-||x*-x||2=0-d(该式在算法迭代过程执行加速调整与先验信息优化操作前一直满足)且γ=1时,式(6)得到的x″是向量x与对应辅助向量z的连线上距方程组真实解 x*最近的点;当0<γ≤1时,x″比更新前的向量x离方程组真实解x*的距离更近。[x',z',d']=lineAcc(x,z,d,γ)的式(7)执行先验信息优化操作,x'=Sup(x″)返回的x′一般比x″与图像的先验信息更接近。图像的先验信息有多种表示方式,很多时候会以某种数学变换来描述,比如全变分(Total variance,TV)范数。当采用TV范数描述先验信息时,本发明方法中的先验信息优化操作x'=Sup(x″)是减小图像的TV范数,即返回的x′比x″具有更小的图像TV范数。[x',z',d']=lineAcc(x,z,d,γ)的式(8)、(9)分别更新了辅助向量z与辅助标量d。执行加速调整与先验信息优化操作[x',z',d']=lineAcc(x,z,d,γ)后,总体说来,更新后的向量x′比更新前的向量x具有更小的测量误差,与图像的先验信息更为接近(如TV范数更小)。Accelerated adjustment and prior information optimization operation [x', z', d']=lineAcc(x, z, d, γ) Formulas (4), (5), (6) perform the accelerated adjustment operation, when || x * -z|| 2 -||x * -x|| 2 =0-d (this formula is always satisfied before the acceleration adjustment and prior information optimization operation is performed in the iterative process of the algorithm) and when γ=1, formula (6 ) obtained x″ is the closest point to the real solution x * of the system of equations on the connection line between the vector x and the corresponding auxiliary vector z; when 0<γ≤1, x″ is closer than the vector x before the update to the real solution x of the system of equations * is closer. Formula (7) of [x', z', d']=lineAcc(x, z, d, γ) performs a priori information optimization operation, and x' returned by x'=Sup(x") is generally better than x" and The prior information of the image is closer. The prior information of an image has various representations, and is often described by some mathematical transformation, such as the Total Variation (TV) norm. When the TV norm is used to describe the prior information, the prior information optimization operation x'=Sup(x") in the method of the present invention is to reduce the TV norm of the image, that is, the returned x' has a smaller value than x" Image TV norm. Formulas (8) and (9) of [x', z', d']=lineAcc(x, z, d, γ) update the auxiliary vector z and the auxiliary scalar d, respectively. After performing the accelerated adjustment and prior information optimization operation [x', z', d'] = lineAcc(x, z, d, γ), in general, the updated vector x' has more Small measurement error, which is closer to the prior information of the image (eg, the TV norm is smaller).
所述步骤(2.1)采用固定投影顺序设定超平面投影顺序,每次迭代第l(l=1,2,...M) 个投影超平面的序号i=sl的值是固定的,则每次迭代下面步骤(2.2.2)中的加速调整与先验信息优化操作针对的是相同的超平面序号;反之,若采用随机投影顺序设定超平面投影顺序,每次迭代第l个投影超平面的序号i=sl是随机的,则每次迭代下面步骤(2.2.2)中的加速调整与先验信息优化操作针对的是不同的超平面序号。The step (2.1) adopts a fixed projection sequence to set the hyperplane projection sequence, and the value of the serial number i=s l of the l (l=1, 2,...M)th projection hyperplane in each iteration is fixed, Then the acceleration adjustment and prior information optimization operations in the following step (2.2.2) in each iteration are aimed at the same hyperplane number; otherwise, if the random projection order is used to set the hyperplane projection order, the lth in each iteration The sequence number i =sl of the projection hyperplane is random, and the acceleration adjustment and prior information optimization operations in the following step (2.2.2) in each iteration are aimed at different hyperplane numbers.
(2.3)k←k+1,即迭代数加1,准备进行下一次迭代。(2.3) k←k+1, that is, the number of iterations is increased by 1, and the next iteration is ready.
下面结合1个具体例子对本发明做进一步的说明。The present invention will be further described below with reference to a specific example.
本实施例对应投影数据不完备的情况,待重建CT图像是一个128×128的二维图像,即图3中的原始图像,对应表示成16384×1的向量x*,A是维度为7200×16384的系统矩阵,即M=7200,N=16384,b=Ax*+e为16384×1的测量数据向量(矩阵A当中含有少量全零的行,处理时将剔除这些数据)。e为零均值高斯白噪声向量,幅值强度为测量数据b的1%。This embodiment corresponds to the situation where the projection data is incomplete. The CT image to be reconstructed is a 128×128 two-dimensional image, that is, the original image in FIG. 3 , which corresponds to a 16384×1 vector x * , and A is a dimension of 7200× The system matrix of 16384, that is, M=7200, N=16384, b=Ax * +e is a 16384×1 measurement data vector (matrix A contains a small number of all-zero rows, which will be eliminated during processing). e is a zero-mean white Gaussian noise vector with an amplitude intensity of 1% of the measured data b.
在不完备投影情况下,为了重建高质量图像,还需要引入一些先验知识进行正则化。本实例中采用全变分(TV)正则化技术,正则化后CT图像重建问题转化为如下目标函数的最小化问题:In the case of incomplete projection, in order to reconstruct high-quality images, it is also necessary to introduce some prior knowledge for regularization. In this example, total variation (TV) regularization technique is used, and the CT image reconstruction problem after regularization is transformed into the minimization problem of the following objective function:
在本实施例中,η=0.004,初始化阶段本发明方法的参数设置为:ρ=1,γ=1,初始向量 x0设为全零向量,每次循环迭代内进行的加速调整与先验信息优化操作个数T=4,采用随机投影顺序。In this embodiment, η=0.004, the parameters of the method of the present invention in the initialization stage are set as: ρ=1, γ=1, the initial vector x 0 is set as an all-zero vector, and the acceleration adjustment and a priori performed in each loop iteration The number of information optimization operations is T=4, and a random projection sequence is used.
在每次迭代过程,首先产生一组1,2,...M的随机排列组合作为投影顺序,然后按随机产生的投影顺序对各超平面进行投影与加速调整与先验信息优化操作。In each iteration process, a group of random permutations and combinations of 1, 2, ... M are generated as the projection order, and then the projection and acceleration adjustment and prior information optimization operations are performed on each hyperplane according to the randomly generated projection order.
对于第1800、3600、5400、7200(即)以外的投影超平面,只执行投影操作(2.2.1),不执行加速调整与先验信息优化操作(2.2.2);对于第1800、3600、5400、7200投影超平面,在执行投影操作(2.2.1)后还执行加速调整与先验信息优化操作(2.2.2)。由于采用的是随机投影顺序,每次迭代第1800、3600、5400、7200投影超平面的序号一般不同。比如,在第一次迭代第1800个投影超平面的序号为353,在第二次迭代第1800个投影超平面的序号为3478,这表示在第一次迭代时对序号为353的超平面进行加速调整与先验信息优化操作,而在第二次迭代时对序号为3478的超平面进行加速调整与先验信息优化操作。For the 1800th, 3600th, 5400th, 7200th (ie ), only the projection operation (2.2.1) is performed, and the acceleration adjustment and prior information optimization operations (2.2.2) are not performed; for the 1800th, 3600, 5400, and 7200 projection hyperplanes, the projection operation is performed After (2.2.1), the accelerated adjustment and prior information optimization operations (2.2.2) are also performed. Due to the random projection order, the serial numbers of the 1800th, 3600th, 5400th, and 7200th projection hyperplanes are generally different in each iteration. For example, the sequence number of the 1800th projection hyperplane in the first iteration is 353, and the sequence number of the 1800th projection hyperplane in the second iteration is 3478, which means that in the first iteration, the hyperplane with sequence number 353 is processed. Accelerate adjustment and prior information optimization operations, and perform accelerated adjustment and prior information optimization operations on the hyperplane with serial number 3478 in the second iteration.
由于本发明方法在迭代过程不依赖于前次迭代变量,因此易于直接结合先验信息实现不完备投影情况下的快速图像重建。本发明方法重建得到的图像与原始图像的对比图如图3所示,本发明方法与结合ART与TV范数优化的算法的平方向量误差收敛曲线图如图4所示,从图中可以看出本发明方法显著提高了收敛速度。Since the method of the present invention does not depend on the previous iteration variable in the iterative process, it is easy to directly combine the prior information to realize the fast image reconstruction under the condition of incomplete projection. The comparison diagram of the image reconstructed by the method of the present invention and the original image is shown in Figure 3, and the square vector error convergence curve diagram of the method of the present invention and the algorithm combining ART and TV norm optimization is shown in Figure 4. It can be seen from the figure The method of the present invention significantly improves the convergence speed.
以上显示和描述了本发明的基本原理、主要特征和本发明的优点。本行业的技术人员应该了解,本发明不受上述实施例的限制,上述实施例和说明书中描述的只是说明本发明的原理,在不脱离本发明精神和范围的前提下,本发明还会有各种变化和改进,这些变化和改进都落入要求保护的本发明范围内。本发明要求保护范围由所附的权利要求书及其等效物界定。The foregoing has shown and described the basic principles, main features and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited by the above-mentioned embodiments, and the descriptions in the above-mentioned embodiments and the description are only to illustrate the principle of the present invention. Without departing from the spirit and scope of the present invention, the present invention will have Various changes and modifications fall within the scope of the claimed invention. The claimed scope of the present invention is defined by the appended claims and their equivalents.
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